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3,5-Bis(Trifluoromethyl)Nitrobenzene

3,5-Bis(Trifluoromethyl)Nitrobenzene

Hongda Chemical

    Specifications

    HS Code

    320408

    Chemical Formula C8H3F6NO2
    Molecular Weight 261.105
    Appearance Colorless to light yellow liquid
    Boiling Point 195 - 196 °C
    Melting Point N/A
    Density 1.549 g/mL at 25 °C
    Solubility Insoluble in water, soluble in organic solvents like ethanol, ether
    Vapor Pressure N/A
    Flash Point 80.6 °C
    Refractive Index 1.427

    As an accredited 3,5-Bis(Trifluoromethyl)Nitrobenzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing 1 kg of 3,5 - bis(trifluoromethyl)nitrobenzene packaged in a sealed, chemical - resistant container.
    Storage 3,5 - bis(trifluoromethyl)nitrobenzene should be stored in a cool, dry, well - ventilated area away from heat sources, open flames, and oxidizing agents. Keep it in a tightly sealed container to prevent leakage. Store it separately from incompatible substances, preferably in a dedicated chemical storage cabinet, following all safety regulations to ensure safe handling and storage.
    Shipping 3,5 - bis(trifluoromethyl)nitrobenzene is shipped in sealed, corrosion - resistant containers. It's transported with strict adherence to hazardous chemical regulations, ensuring proper handling and safety during transit.
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    3,5-Bis(Trifluoromethyl)Nitrobenzene 3,5-Bis(Trifluoromethyl)Nitrobenzene
    General Information
    Historical Development
    I have heard of the chemical industry, there are many categories and different substances. Today, 3,5-bis (trifluoromethyl) nitrobenzene, its evolution in the history of chemical industry, also has traces to be found.
    In the past, chemical industry was just emerging, exploration was unknown, and all kinds of substances were waiting to be studied. Although it was not as good as this thing at that time, the road of scientific evolution gradually began. Years have passed, and researchers have been diligent and unremitting, and technology has advanced. The research on fluorine chemistry and nitro compounds has deepened, and the insight into the reaction mechanism and synthesis path has gradually become clear.
    After years of experiments and unremitting attempts, the method of synthesizing 3,5-bis (trifluoromethyl) nitrobenzene was obtained. Since its birth, it has emerged in various fields such as medicine and materials, contributing to the development of the industry. Its historical evolution has witnessed the brilliance of chemical science and opened up more possibilities in the future.
    Product Overview
    3,5-Bis (trifluoromethyl) nitrobenzene is a compound that has attracted much attention in the field of organic synthesis. Its appearance is colorless to light yellow liquid and has a special odor. This compound is widely used in many fields such as medicine, pesticides and materials science.
    As far as the synthesis path is concerned, m-xylene is often used as the starting material and is prepared through multiple steps such as halogenation, nitrification and trifluoromethylation. Each step of the reaction requires precise control of the reaction conditions, such as temperature, catalyst and reactant ratio, to ensure the purity and yield of the product.
    In the field of medicine, it can be used as a key intermediate to synthesize drug molecules with specific biological activities. In terms of pesticides, it can help to develop new pesticides with high efficiency and low toxicity. In the field of materials science, it can also contribute to the synthesis of materials with special properties.
    In conclusion, 3,5-bis (trifluoromethyl) nitrobenzene has broad application prospects in many fields due to its unique structure and properties, which is of great significance to promoting the development of related industries.
    Physical & Chemical Properties
    "On the physical properties and chemical properties of 3,5-bis (trifluoromethyl) nitrobenzene"
    Fu 3,5-bis (trifluoromethyl) nitrobenzene is an important intermediate in organic synthesis. Its physical properties are colorless to light yellow liquid at room temperature, with a special odor. The boiling point is quite high, about a specific temperature range, due to intermolecular forces. And the density is greater than water, insoluble in water, but soluble in common organic solvents, such as ethanol, ether, etc. This is the reason why it is similar to miscibility.
    On its chemical properties, the presence of nitro groups makes it highly oxidizing. The benzene ring is connected with trifluoromethyl, and the electron cloud density of the benzene ring is reduced due to the strong electronegativity of fluorine, and the electrophilic substitution reaction activity is weakened. However, under appropriate conditions, many reactions can still occur, such as the reaction with nucleophiles, showing unique chemical properties and being widely used in the field of organic synthesis.
    Technical Specifications & Labeling
    There is a product named 3,5-Bis (trifluoromethyl) nitrobenzene. The technical specifications and identification (commodity parameters) for its preparation are the requirements of our research. To make this product, we must first understand the purity of the raw materials and control its dosage, such as the method of harmony, which is accurate. When reacting, the degree of temperature and pressure should not be ignored, but should be stable and suitable, so that the transformation should be smooth.
    As for the label, its characteristics, such as color, taste, and state, should be specified, and its danger should be noted to warn everyone. It is also written that the number of its main components and the accuracy of the scalar quantity should not be different. In this way, in the preparation and application, there are all dependencies, and the quality can be guaranteed, and it can be used safely.
    Preparation Method
    The preparation method of 3,5-bis (trifluoromethyl) nitrobenzene is related to the raw materials and production process, reaction steps and catalytic mechanism.
    First take the appropriate raw materials and mix them in a specific ratio. If the compound containing trifluoromethyl is based on the nitrogenation reagent, according to the ancient method, it is necessary to precisely control the proportion of materials to make the reaction smooth.
    The reaction step is crucial. In an appropriate reaction vessel, adjust it to a specific temperature and pressure to make the raw materials chemically react. Or initiate a substitution reaction first, so that the trifluoromethyl is firmly connected to the benzene ring, and then carry out the nitrogenation step. The two are orderly and cannot be disrupted.
    Catalytic mechanism is also key. Selecting suitable catalysts can promote the reaction to proceed efficiently. Such as metal catalysts or acid-base catalysts, with its activity check point, reduce the activation energy of the reaction, increase the reaction rate, and make the product yield and purity good. In this way, the best products of 3,5-bis (trifluoromethyl) nitrobenzene can be obtained.
    Chemical Reactions & Modifications
    Nowadays, there is a chemical substance called 3,5-bis (trifluoromethyl) nitrobenzene. The study of its chemical reaction and modification is very important.
    Looking at this chemical substance, its structure is unique, containing trifluoromethyl and nitro groups. To make it have better characteristics, it is necessary to study the reaction carefully. The method of the past may have drawbacks, the product is not pure, and the efficiency is also low.
    Today's chemists are dedicated to improving the reaction. Using a new catalyst can change the reaction path, making the reaction conditions mild and the product pure. There are also those who start with the reaction solvent, which can promote the reaction rate and make the reaction easier to control.
    There are also ways to explore modification, introducing other groups into the benzene ring to change its physical and chemical properties. It can increase its stability or change its solubility, all of which are ways to expand its use.
    All of these are to make 3,5-bis (trifluoromethyl) nitrobenzene have better performance and play a greater role in chemical, pharmaceutical and other fields.
    Synonyms & Product Names
    3,5-Bis (trifluoromethyl) nitrobenzene is also a chemical product. It is used in the chemical industry and has a wide range of uses. There are many aliases for this product, all of which are well known in the industry.
    As far as commercial names are concerned, there are also various titles, which are commonly used by merchants and traders. The study of its aliases and trade names is crucial to our chemical researchers.
    Looking at the method of its preparation, it has undergone various explorations. In the past, the predecessors worked hard to find the best way. Today's preparation process has been refined, but the sorting of its aliases and trade names cannot be slack. Because of chemical transactions and academic exchanges, accurate appellations can only be correct.
    This 3,5-bis (trifluoromethyl) nitrobenzene, with its characteristics, has made a name for itself in the pharmaceutical, materials and other industries. Detailed distinctions between its synonyms and trade names can show its status in market circulation, and also help industry norms and promote the progress of chemical research and application.
    Safety & Operational Standards
    "Specification for safety and operation of 3,5-bis (trifluoromethyl) nitrobenzene"
    Fu 3,5-bis (trifluoromethyl) nitrobenzene is an important compound in chemical research. During its research and preparation process, safety and operation standards are of paramount importance.
    First, safety, this compound is dangerous. Its nature is active, or it reacts violently with other things. When storing, it must be in a cool, dry and well-ventilated place, away from fire and heat sources to prevent accidents. The storage container must also be firmly sealed to prevent its leakage. If it leaks accidentally, it should be disposed of according to the established method as soon as possible. Small leaks can be collected by adsorption of inert materials such as sand and vermiculite; large leaks need to be delineated as a warning area, evacuated, and properly handled by professionals.
    As for the operation specifications, the operator must first be familiar with its properties and reaction mechanism. During operation, protect yourself in front of suitable protective equipment, such as protective clothing, gloves, goggles, etc. During the experimental process, strictly control the temperature and pressure, and operate according to a precise process. Stirring, heating and other steps must be done with caution to avoid runaway reaction. And the operating environment needs to have good ventilation facilities to drain harmful gases.
    Furthermore, after the experiment, the remaining 3,5-bis (trifluoromethyl) nitrobenzene and related wastes should not be discarded at will. They must be collected in accordance with environmental protection regulations and handed over to professional institutions for treatment to avoid polluting the environment.
    In short, in the research and application of 3,5-bis (trifluoromethyl) nitrobenzene, strict adherence to safety and operating standards can achieve the purpose of research and ensure personal and environmental safety.
    Application Area
    3,5-Bis (trifluoromethyl) nitrobenzene is also a product of the chemical industry. Its application field is quite extensive. In pharmaceutical chemistry, it is often the key raw material for the synthesis of special drugs. With its unique chemical structure, it can create many drugs for difficult diseases. In the field of materials science, based on this, materials with special properties can be developed, such as protective materials that are resistant to extreme environments. In the field of agricultural chemistry, it can help synthesize highly efficient and low-toxicity pesticides to protect crops from pests and diseases. Its application in various fields depends on its unique chemical properties, or participates in specific reactions, or endows products with unique characteristics. Therefore, 3,5-bis (trifluoromethyl) nitrobenzene plays a crucial role in many industries, promoting continuous evolution and innovation in related fields.
    Research & Development
    Today, we are studying 3,5-bis (trifluoromethyl) nitrobenzene, which is of great significance in the field of chemistry. We are dedicated to exploring its preparation methods and analyzing the effects of different reaction conditions on its yield. After repeated experiments, with specific raw material ratio, precise control of temperature and reaction time, a better synthesis path was found.
    In terms of property research, it is essential to investigate its physical and chemical properties in detail, clarify its stability and reactivity, and provide a basis for its application. At the same time, consider its solubility in different solvents to provide a basis for subsequent applications.
    Looking to the future, it is expected to further optimize the synthesis process, improve yield and reduce costs. We are actively exploring its potential applications in new materials, drug research and development, and hope that this material can promote the progress and development of science and technology in more aspects, and contribute to chemical research and practical applications.
    Toxicity Research
    Study on the toxicity of 3,5-bis (trifluoromethyl) nitrobenzene
    In the chemical industry, new products emerge, but the research on its toxicity is related to people's health and cannot be ignored. Today, 3,5-bis (trifluoromethyl) nitrobenzene is the object of research.
    This compound may have its unique appearance, but its toxicity needs to be investigated in detail. In the experimental environment, take various living beings as a test, and observe the changes it feels when it is affected by this substance. Or see the differences in its physiological functions and behavior.
    After research, it is known that it may enter the body of living beings, disturb the order of metabolism and damage the ability of its viscera. If you accidentally touch it, it may be irritating to the skin; if you inhale its qi, it may hurt your breathing.
    Therefore, when producing and using this product, strict precautions should be taken to ensure people's safety and avoid the danger of poison. This is the heavy responsibility of my chemical researchers.
    Future Prospects
    Wuguanfu 3,5-Bis (trifluoromethyl) nitrobenzene is unique in its properties and has a wide range of uses. In today's chemical research and development, it has been obtained, but there is still a long way to go in the future.
    It can be used as a key raw material in the field of synthesis, and it can open up a new way in the chemical industry. With the advance of science and technology, the research method should improve the refinement, and the yield will definitely rise again. And its derivatives are also expected to show their edge in medicine and materials.
    In the future, the power of new technologies may be used to make the preparation of this product simpler and the cost will drop. In terms of environmental protection, it is also expected to achieve a better environment, harmless to heaven and earth, and beneficial to all people. Therefore, the future of 3,5-bis (trifluoromethyl) nitrobenzene will be as bright as the sun, bringing endless joy to our generation of chemical researchers.
    Where to Buy 3,5-Bis(Trifluoromethyl)Nitrobenzene in China?
    As a trusted 3,5-Bis(Trifluoromethyl)Nitrobenzene manufacturer, we deliver: Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements. Technical Excellence: Precision-engineered solutions backed by R&D expertise, from formulation to end-to-end delivery. Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.
    Frequently Asked Questions

    As a leading 3,5-Bis(Trifluoromethyl)Nitrobenzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

    What are the main uses of 3,5-bis (trifluoromethyl) nitrobenzene?
    The main use of 3,5-bis (triethoxysilyl) benzene is in materials science and related fields.
    In materials science, one of them is used to prepare high-performance organic-inorganic hybrid materials. Because it contains siloxane groups, it can be hydrolyzed and condensed to form a siloxane network, which can be combined with organic polymers or other inorganic components. For example, introducing it into polymer matrices, such as epoxy resins, polyurethane, etc., can significantly improve the mechanical properties, thermal stability and chemical resistance of the material. This is because the siloxane network can enhance the interaction within the material to form a stable structure.
    Second, it has important uses in the field of coatings. The addition of this compound can improve the adhesion, wear resistance and weather resistance of the coating. The siloxane group can react with the hydroxyl group and other groups on the surface of the substrate to enhance the chemical bonding between the coating and the substrate, so that the coating adheres more firmly. And the formed siloxane structure can improve the compactness of the coating and resist external environmental erosion.
    Third, it is also used in the preparation of functional fillers. The surface of the inorganic filler can be modified to make it more compatible with the polymer matrix. When the filler modified by this compound is dispersed in the polymer, it can be evenly distributed, enhancing the interfacial bonding force between the filler and the polymer, thereby improving the comprehensive properties of the composite.
    Furthermore, in the field of self-assembly and template synthesis, due to its unique molecular structure, it can participate in the self-assembly process as a construction unit to form ordered nanostructures. It can also provide a specific spatial environment for template synthesis, guiding the generation of materials with special morphologies and properties.
    In summary, 3,5-bis (triethoxysilyl) benzene plays a key role in material preparation and modification, promoting the development of materials science and related industries.
    What are the synthesis methods of 3,5-bis (trifluoromethyl) nitrobenzene?
    The synthesis of 3,5-bis (triethylamino) carbonyl benzoic acid has various paths, let me go through them one by one.
    First, it can be initiated through benzoic acid. First, the benzoic acid undergoes a substitution reaction with a suitable halogenated alkane under specific reaction conditions, and a halogen atom is introduced. Then, the halogenated benzoic acid undergoes a nucleophilic substitution reaction with triethylamine, so that the triethylamine group is connected to the specific position of the benzoic acid, and then the synthesis of 3,5-bis (triethylamino) carbonyl benzoic acid is achieved. The key to this path is to precisely control the substitution reaction conditions to ensure that the halogen atom is introduced in the right position and the nucleophilic substitution reaction can be carried out efficiently.
    Second, benzaldehyde is used as the starting material. First, benzaldehyde is oxidized into benzoic acid. In this oxidation step, a suitable oxidizing agent and reaction environment need to be selected to ensure the selectivity and yield of the oxidation reaction. Then, like the method of benzoic acid initiation, the benzoic acid is connected to a bis (triethylamino) group through halogenation, nucleophilic substitution, etc., and the final product is obtained. In this way, the oxidation step of benzaldehyde is very important, and the type, dosage, reaction temperature, time and other factors have a significant impact on the formation of the product.
    Third, benzene can also be used. The carboxyl group is introduced into the benzene ring through the Fu-Ke acylation reaction. This step requires the selection of suitable acylation reagents and catalysts to promote the reaction in the desired direction. The subsequent steps are similar to the previous two. The structure of 3,5-bis (triethylamino) carbonylbenzoic acid is constructed through reactions such as halogenation and nucleophilic substitution. In this path, the Fu-Ke acylation reaction is the key reaction of initiation, and the regulation of reaction conditions has a great influence on the yield and purity of the product.
    All kinds of synthesis methods have their own advantages and disadvantages. The choice of starting materials depends on factors such as the availability of raw materials, cost, and difficulty of reaction. The fine regulation of reaction conditions is also the key to the synthesis of high purity 3,5-bis (triethylamino) carbonylbenzoic acid.
    What are the physical properties of 3,5-bis (trifluoromethyl) nitrobenzene?
    3% 2C5-bis (triethylamino) carbonyl benzoic acid, this material has the following physical properties:
    Viewed, it is often in the state of white to slightly yellow crystalline powder, like fine powder, uniform texture, in sunlight, it can be seen that its delicate luster, shining. Its powder particle size is fine and uniform, good fluidity, easy to pour and mix.
    Smell, the smell is extremely light, almost odorless, placed under the nose to smell, only a slight smell, no pungent, odor and other uncomfortable taste, this characteristic makes it advantageous in many application scenarios sensitive to odor.
    Measure its melting point, which is within a specific temperature range. This temperature is the critical value for its transformation from solid to liquid. At this temperature, the solid crystal gradually melts into a clear liquid. This melting point characteristic is of great significance to its synthesis, purification and identification, and is one of the key physical parameters.
    Its solubility is also an important property. In organic solvents, such as common ethanol, acetone, etc., it exhibits good solubility and can quickly dissolve to form a uniform solution; however, in water, the solubility is relatively weak and only slightly soluble. This difference in solubility determines its application direction in different systems. It can be used as a good reactant or intermediate in organic phase reactions, while in aqueous phase systems, special treatment is required.
    In addition, density is also its inherent property. The specific density makes it follow the corresponding physical law distribution when mixed with other substances, which affects the stability and properties of the mixture. Its stability is good, and it can be stored for a long time without significant chemical changes under conventional environmental conditions, providing convenience for its storage and transportation.
    What are the chemical properties of 3,5-bis (trifluoromethyl) nitrobenzene?
    3% 2C5-bis (triethylamino) quinolinyl naphthalene, this material has unique properties and is common to organic compounds. Its appearance is often crystalline, the color may be white to yellowish, and the texture is fine.
    In terms of solubility, it has good solubility in organic solvents such as dichloromethane, chloroform, N, N-dimethylformamide, but it is difficult to dissolve in water. This characteristic is due to its molecular structure rich in hydrophobic groups, which has a weak force on water molecules, but is easy to form van der Waals forces or other weak interactions with organic solvent molecules.
    Thermal stability, the properties are stable before reaching a certain temperature. If the temperature is too high, the molecular structure will be damaged and the decomposition reaction will be triggered. This is due to the intensification of the vibration of the intramolecular chemical bond at high temperature, and the bond energy is insufficient to maintain the integrity of the structure.
    The chemical activity is significant, and its nitrogen-containing heterocyclic structure and alkyl substituent give special reactivity. Nitrogen atoms have solitary pairs of electrons, which can act as electron donors and react with electrophilic reagents. For example, in nucleophilic substitution reactions, they can attack electrophilic centers to form new chemical bonds.
    In addition, the conjugate system gives it unique optical properties. When excited by light, the electron transition produces fluorescence phenomenon, which has broad application prospects in the field of fluorescent materials. Due to its structure and electron distribution characteristics, the characteristics of fluorescence wavelength, intensity and quantum yield are related to the degree of conjugation and the type of substituent.
    Due to its special physicochemical properties, it has potential application value in the fields of materials science, organic synthesis and biomedicine. It can be used as a fluorescent probe for biological imaging or as an intermediate in organic synthesis to construct complex compounds.
    What should be paid attention to when storing and transporting 3,5-bis (trifluoromethyl) nitrobenzene?
    When storing and transporting 3,5-bis (triethylamino) carbonylbenzoic acid, the following key points should be paid attention to.
    Storage, the first choice of environment. This substance should be placed in a cool, dry and well-ventilated place to prevent moisture and heat. Because moisture is prone to chemical reactions such as hydrolysis, heat may accelerate its decomposition and damage its quality. And it must be kept away from fire and heat sources. Because the substance may have certain flammability, it may cause danger in case of open flames and hot topics.
    Furthermore, storage containers are also crucial. Choose corrosion-resistant materials, such as glass or specific plastic containers, to avoid their reaction with the container. At the same time, the container must be tightly sealed to prevent the intrusion of air, moisture, etc.
    For transportation, the packaging must be stable and reliable. According to transportation regulations, suitable packaging materials should be used to ensure that there will be no damage and leakage due to vibration and collision during transportation. And transportation vehicles should be equipped with corresponding fire equipment and leakage emergency treatment equipment, just in case.
    In addition, transportation and storage should strictly avoid mixing with oxidants, acids, alkalis and other substances. Due to its chemical properties, contact with these substances or react violently, endangering safety. At the same time, relevant operators should be professionally trained and familiar with the characteristics of the substance and emergency treatment methods, so as to ensure the safety of 3,5-bis (triethylamino) carbonylbenzoic acid during storage and transportation.