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3,5-Bis(Trifluoromethyl) Iodobenzene

3,5-Bis(Trifluoromethyl) Iodobenzene

Hongda Chemical

    Specifications

    HS Code

    465120

    Chemical Formula C8H3F6I
    Molar Mass 349.99 g/mol
    Appearance Colorless to light yellow liquid
    Boiling Point Around 172 - 174 °C
    Density 1.986 g/cm³
    Solubility Soluble in common organic solvents like dichloromethane, chloroform
    Purity Typically available in high purity, e.g., 98%+
    Cas Number 678-37-5

    As an accredited 3,5-Bis(Trifluoromethyl) Iodobenzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing 100g of 3,5 - bis(trifluoromethyl) Iodobenzene in a sealed, labeled glass bottle.
    Storage Store 3,5 - bis(trifluoromethyl) iodobenzene in a cool, dry place away from heat and ignition sources. Keep it in a tightly sealed container to prevent evaporation and exposure to air or moisture. As it's a chemical, store it in a designated chemical storage area, separated from incompatible substances to avoid potential reactions.
    Shipping 3,5 - bis(trifluoromethyl) Iodobenzene is shipped in well - sealed, corrosion - resistant containers. Strict adherence to hazardous chemical shipping regulations ensures safe transport, minimizing risks during transit.
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    3,5-Bis(Trifluoromethyl) Iodobenzene 3,5-Bis(Trifluoromethyl) Iodobenzene
    General Information
    Historical Development
    Those who have heard of the chemistry of ancient times have tried to study a thing called 3,5-bis (trifluoromethyl) iodobenzene. This substance has its origin, but no one knows its nature. At the beginning, the sages explored its traces in the micro-end, and studied its quality with simple tools. Although the journey was difficult and difficult, their determination has not changed.
    The years have passed, and the wisdom of the masters has gradually gathered. Its nature and its system have all been gained. It was made by rough method at first, and then the technique has become more refined, and the yield has also increased. It was rare to ask in the past, but it can be used in all kinds of ways today. From this perspective, the path of chemistry is like sailing against the current, making unremitting progress, so as to have the prosperity of this substance.
    Product Overview
    There is now a substance called 3,5-bis (trifluoromethyl) iodobenzene. Its shape may be colorless to light yellow liquid, with special chemical properties. In this compound, on the benzene ring, there are trifluoromethyl groups at the 3rd and 5th positions, respectively, and iodine atoms at the 1st position. Because of its fluorine-containing atoms, it has high electronegativity, so this substance exhibits unique reactivity and stability.
    From the perspective of application, 3,5-bis (trifluoromethyl) iodobenzene is quite important in the field of organic synthesis. It is often used as a key intermediate for the preparation of various fluorine-containing fine chemicals, or drugs, pesticides, etc. Due to its special structure, it can participate in many organic reactions, such as palladium-catalyzed coupling reactions, which assist chemists in constructing complex organic molecular structures and lay the foundation for the creation of novel active compounds.
    Physical & Chemical Properties
    3,5-Bis (trifluoromethyl) iodobenzene, an organic compound. Its physical and chemical properties are crucial to chemical research. The shape of this substance is at room temperature or in a liquid state, with a clear and transparent color and a special odor. Looking at its physical properties, the melting point and boiling point have fixed numbers. The melting point is about [X] ° C, the boiling point is about [X] ° C, and the density is heavier than water, about [X] g/cm ³. Its solubility is easily soluble in organic solvents such as ethanol and ether, but it is difficult to dissolve in water.
    On its chemical properties, it has unique activity due to the presence of iodine atoms and trifluoromethyl. Iodine atoms can undergo nucleophilic substitution reactions. When encountering nucleophilic reagents, iodine is easily replaced to form new compounds. Trifluoromethyl has strong electron absorption, which reduces the electron cloud density of benzene ring, making it difficult for its electrophilic substitution reactions to occur. These physical and chemical properties can be important raw materials in the field of organic synthesis, helping to form a variety of complex organic molecules and promoting the progress of chemical research.
    Technical Specifications & Labeling
    There is a substance today, named 3,5-bis (trifluoromethyl) iodobenzene. If you want to clarify its technical specifications and identification (product parameters), you should check it carefully.
    On its technical specifications, it is necessary to determine its purity geometry and a number of impurities. Its properties may be distinct in color, or it may have a specific taste. In terms of chemical properties, its stability should be tested. In case of changes in temperature, light, humidity, etc., how to react.
    As for the label, it should be marked with an accurate name and a chemical formula to clarify its structure. Mark it with a hazard warning. If it is toxic or corrosive, it must be notified in detail. In addition, in the product parameters, the packaging specifications and storage conditions should not be ignored to ensure its quality and use it correctly. This is all about the technical specifications and labeling of 3,5-bis (trifluoromethyl) iodobenzene.
    Preparation Method
    In the process of making 3,5-bis (trifluoromethyl) iodobenzene, the raw materials and production process, reaction steps and catalytic mechanism are the key. Take a certain raw material and mix it in a suitable reaction vessel according to a specific ratio. First, prereact under a certain mild condition to make the raw materials initially blend. Then heat up to a certain degree and add a special catalyst, which is the key to accelerating the reaction. The catalytic mechanism is that the catalyst activity check point interacts ingeniously with the raw material to reduce the reaction energy barrier and promote the efficient progress of the reaction. After multiple precise reactions, the reaction conditions are adjusted one after another, such as temperature control and pressure regulation, so that the reaction follows the established path and finally obtains 3,5-bis (trifluoromethyl) iodobenzene. This production process involves fine-tuning each step to achieve high-efficiency, high-purity production.
    Chemical Reactions & Modifications
    Taste the wonders of chemical industry, it is related to the change of substances, and the reaction and properties are particularly important. This paper discusses the reaction and modification of 3,5-bis (trifluoromethyl) iodobenzene.
    The way of its reaction often involves nucleophilic substitution and coupling reactions. During nucleophilic substitution, iodine atoms have good activity and can be replaced by nucleophilic reagents, introducing other groups to open up its derivation path. In the coupling reaction, it can be combined with conjugated systems such as alkenes and alkynes to build a complex structure.
    As for modification, it is to achieve special properties, or to add functional groups to the benzene ring to adjust its electron cloud distribution and change its polarity and solubility. In this way, it can increase its stability or give it photoelectric activity, which is of great use in various fields of materials and medicine. Viewing and modifying it is the key to exploring a new path in chemical industry, and it is necessary to delve into it.
    Synonyms & Product Names
    3,5-Bis (trifluoromethyl) iodobenzene, which is quite important in the field of chemical industry today. Its synonymous names are also many. Many other names have been passed down in the world due to their appearance, properties, or uses and production methods.
    Although the ancient craftsmen did not hear of this exact name, the principles of chemical industry are in the same vein. Looking at today's 3,5-bis (trifluoromethyl) iodobenzene, its uses are widely involved in medicine and materials. In the past, the production of medicinal stones and the choice of materials all relied on the wisdom of craftsmen. Today's product, with its specificity, can guide the direction of reaction and increase the effect of medicine in the synthesis of medicine; in the preparation of materials, it can change the quality of materials and expand their use.
    Its trade name is also an industry logo. Different brands, with their quality and craftsmanship, give this product a unique name. However, the root cause is this 3,5-bis (trifluoromethyl) iodobenzene. In the city, the names of various products compete, and their essence is the same, all of which are to promote the progress of chemical industry and benefit people's livelihood.
    Safety & Operational Standards
    "On the safety and operation specifications of 3,5-bis (trifluoromethyl) iodobenzene"
    There are chemical substances 3,5-bis (trifluoromethyl) iodobenzene today. Its preparation and use are related to safety and operation standards, and should not be careless.
    This substance has unique chemical properties. When preparing, the ratio of all raw materials must be accurate, and the heat control must be just right. The utensils used must be clean and dry to prevent impurities from mixing in, causing reaction deviations and endangering safety.
    When operating, the experimenter should wear protective clothing, goggles and gloves to avoid contact with the skin and eyes. Because it may be irritating, if accidentally contaminated, quickly rinse with plenty of water and seek medical treatment.
    Operate in a well-ventilated place to prevent the accumulation of harmful gases. If there is gas escaping, do not panic, quickly turn off the relevant equipment, and take ventilation to disperse.
    When storing, it should be placed in a cool, dry and ventilated place, away from fire sources and oxidants. Classified storage, do not mix with other things to prevent mutual reaction and cause danger.
    During transportation, strict regulations must also be followed. Packaging must be sturdy, clearly marked, and indicate its characteristics and precautions.
    In short, when treating 3,5-bis (trifluoromethyl) iodobenzene, it is necessary to prepare it for use, storage, and transportation in accordance with safety and operating standards, so that scientific research can be carried out smoothly.
    Application Area
    In today's world, there is a name of 3,5 - Bis (Trifluoromethyl) Iodobenzene. This chemical substance has a wide range of uses. In the field of medicine, it can be the basis for creating new agents. With its special structure, it can be linked with various molecules to help form specific drugs and cure various diseases.
    In the context of material science, it also shows its ability. It can be used to prepare materials with specific properties, such as those with excellent electrical and optical properties, to meet the needs of electronics, optics and other industries.
    In the process of organic synthesis, it is an important intermediate. With its lively chemistry, it can trigger a variety of reactions, build complex organic molecular structures, expand the boundaries of organic synthesis, and provide assistance for the development of many fields.
    Research & Development
    There is a chemical substance today, called 3,5-bis (trifluoromethyl) iodobenzene. I am a chemical researcher and study it carefully. The properties of this substance are specific and it is quite useful in organic synthesis.
    I first investigated its structure. The position of trifluoromethyl and iodine atoms affects its reactivity. After repeated experiments, I explored its reaction with various reagents. Or with the help of catalysts, it combines with alkenes to form novel compounds.
    In the process of research, there are many difficulties. The control of reaction conditions is very critical. Temperature, pressure, and solvent selection are all related to the quality and quantity of the product. However, I have worked tirelessly to gain the essentials.
    Looking to the future, this substance has infinite potential. It is expected to shine in the field of drug synthesis. It will contribute to the progress of medicine and the development of chemical research.
    Toxicity Research
    Today there is a substance called 3,5-bis (trifluoromethyl) iodobenzene. I am a chemical researcher who specializes in the toxicity of this substance. The structure of this substance is unique, containing trifluoromethyl and iodine atoms, and its physical and chemical properties or toxicity are special.
    After many investigations, it has been observed that its reaction in living organisms may affect cell metabolism and damage organs. However, the depth of toxicity varies depending on the route of exposure and dosage. If ingested orally, the stomach bears the brunt; if exposed to the skin, it may cause irritation and allergies.
    Although current research has not fully solved its toxicology, we should be cautious. In the experimental and production room, strictly abide by the procedures to prevent leakage and ensure safety. The deeper the follow-up research, the better the toxicity, and the safety of people and the environment.
    Future Prospects
    I have tried to study chemical things, and now I look at 3,5 - Bis (Trifluoromethyl) Iodobenzene. Its unique nature may have extraordinary uses in various fields of chemical industry. Although the current understanding is limited, my heart is looking to the future.
    In the future, this thing may emerge in the creation of new materials, which help materials have specific properties, such as better corrosion resistance and heat resistance. Or add bricks to the research and development of medicine, lead to new ways for the formation of new drugs, and treat various diseases in the world. It may also shine in the field of electronics and promote the performance of electronic devices.
    I am convinced that with time and detailed investigation, 3,5-Bis (Trifluoromethyl) Iodobenzene will be able to show its brilliance, bring many surprises to all karma, and bring many surprises to the future world, and achieve extraordinary results.
    Where to Buy 3,5-Bis(Trifluoromethyl) Iodobenzene in China?
    As a trusted 3,5-Bis(Trifluoromethyl) Iodobenzene manufacturer, we deliver: Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements. Technical Excellence: Precision-engineered solutions backed by R&D expertise, from formulation to end-to-end delivery. Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.
    Frequently Asked Questions

    As a leading 3,5-Bis(Trifluoromethyl) Iodobenzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

    What are the main uses of 3,5-bis (trifluoromethyl) iodobenzene?
    3,5-Bis (triethylamino) pyridine, which has a wide range of uses and has its presence in many fields.
    In the field of organic synthesis, it is often used as a catalyst. Due to its unique electronic structure and basic properties, it can effectively catalyze many organic reactions. For example, in esterification reactions, it can speed up the reaction process, improve the reaction efficiency, and convert carboxylic acids and alcohols into ester compounds more rapidly. In nucleophilic substitution reactions, it can also play a key catalytic role, promoting the reaction between halogenated hydrocarbons and nucleophiles, promoting the formation of new chemical bonds, and assisting in the synthesis of various organic compounds, providing strong support for the development of organic synthesis chemistry.
    In the field of materials science, 3,5-bis (triethylamino) pyridine also has important uses. It can participate in the preparation of functional materials, such as the synthesis process of some polymer materials. By using it rationally, the structure and properties of the material can be regulated, and the solubility, thermal stability, mechanical properties of the material can be changed. For example, when preparing specific conductive polymer materials, adding this substance may optimize the electrical conductivity of the material and broaden the application range of the material in the field of electronic devices, such as in the manufacture of electronic components such as new batteries and sensors.
    In the field of medicinal chemistry, it also plays an important role. It can be used as a key intermediate in drug synthesis, and its special chemical structure can be used to construct and modify drug molecules. For some biologically active drug molecules, 3,5-bis (triethylamino) pyridine is used as the starting material or key reagent in the synthesis path, and through a series of chemical reactions, drugs with specific pharmacological activities are obtained, providing an effective way for drug research and development and innovation, and promoting the progress of the pharmaceutical field.
    What are the synthesis methods of 3,5-bis (trifluoromethyl) iodobenzene?
    There are various methods for the synthesis of Fu 3,5-bis (triethoxysilyl) benzene, which are described in this article.
    First, benzene is used as the starting material. First, benzene and halosilane are substituted in the presence of a specific catalyst, such as a suitable metal complex catalyst, under certain temperature and pressure conditions. This reaction requires precise temperature control to ensure that the reaction proceeds in the direction of generating 3-halo-5- (triethoxysilyl) benzene to avoid excessive side reactions. The target product 3,5-bis (triethoxysilyl) benzene was obtained by substituting the 3-halogen atom with triethoxysilyl group through suitable reagents and reaction conditions.
    Second, it can be started from the silane derivative containing benzene ring. This derivative undergoes a specific functional group conversion reaction, for example, by selecting a suitable base and reaction solvent, some groups on the silane are eliminated or replaced, and the desired triethoxysilyl group is gradually introduced. In this process, the polarity of the solvent, the strength and dosage of the base all have a great influence on the reaction process and the purity of the product, which needs to be carefully regulated.
    Third, the benzene substitute is used as the starting point. If the substituent is in the right position on the benzene ring, the hydrosilylation reaction can be used to add the hydrosilica reagent to the specific position of the benzene ring under the action of the catalyst, and then the triethoxy silicon group can be introduced. This reaction requires attention to the activity and selectivity of the catalyst. At the same time, the anhydrous and oxygen-free conditions of the reaction system also need to be strictly controlled to prevent the ineffective decomposition of the hydrosilica reagent and the oxidation of the product.
    When synthesizing this compound, the purity of the raw material, the precise regulation of the reaction conditions, and the separation and purification steps are all crucial. Different synthesis methods have their own advantages and disadvantages. According to the actual experimental conditions, the availability of raw materials, and the purity requirements of the target product, etc., the best one should be selected and used.
    What are the physical properties of 3,5-bis (trifluoromethyl) iodobenzene?
    3,5-Bis (triethoxysilyl) benzoic acid is a class of organosilicon compounds. Its physical properties are unique and are described as follows:
    Looking at its properties, under room temperature and pressure, it is mostly white to white powder, with a fine texture, just like frost and snow. This appearance is easy to observe and operate.
    When it comes to melting point, it is usually in a specific temperature range. The characteristics of this melting point are of great significance for the identification, purity judgment and related processing of compounds. When the temperature gradually rises to the melting point, the substance gradually melts from a solid state to a liquid state. This phase transition process follows the laws of physics and lays the foundation for its application.
    Solubility is also an important physical property. It exhibits good solubility in many organic solvents, such as toluene, xylene and other aromatic solvents. This property makes it possible to disperse it uniformly with the help of these solvents in the preparation of coatings, adhesives and other products, and then exert its unique properties. However, in water, its solubility is very small, which is due to the large proportion of organic groups in its molecular structure and the weak interaction between water molecules.
    In addition, the compound has certain thermal stability. In the moderate temperature range, its chemical structure can remain relatively stable, preventing rapid decomposition or other chemical reactions due to heat. This thermal stability is crucial in application scenarios in high temperature environments, such as high temperature coatings, electronic packaging materials, etc., to ensure that the material maintains stable performance during use.
    Its density is also a specific value, and this physical quantity reflects the mass per unit volume of a substance. Accurately knowing its density is indispensable in product formulation design, quality control, etc., and is related to product performance and quality.
    What are the chemical properties of 3,5-bis (trifluoromethyl) iodobenzene?
    3,5-Bis (triethylamino) pyridine is an organic compound. Its chemical properties are particularly critical and it has important uses in many fields. In ancient Chinese, it is described as follows:
    acid-base
    This compound is weakly basic. The nitrogen atom of the pyridine ring has a pair of lone pairs of electrons, which can accept protons, so it is alkaline. If it is in a suitable solution environment, it can react with acids to form corresponding salts. Due to the electronegativity of the nitrogen atom, the pyridine ring exhibits a certain electron cloud density, which is easy to attract protons. This is the root of its alkalinity.
    Nucleophilicity
    3,5-bis (triethylamino) pyridine exhibits a certain degree of nucleophilicity because it contains nitrogen atoms, and the triethylamino groups around the nitrogen atoms can enhance its electron cloud density. In organic synthesis reactions, it can be used as a nucleophilic reagent to attack electrophilic reagents such as halogenated hydrocarbons. The mechanism of this nucleophilic reaction is that the nitrogen atom of the nucleophilic reagent attacks the electron-deficient center of the electrophilic reagent with its lone pair of electrons, and then forms a new chemical bond, which is of great significance in the construction of organic molecular structures.
    Coordination
    Its nitrogen atom can form a coordination bond with metal ions. Since the lone pair of electrons of the nitrogen atom can be supplied to the metal ion, the sharing of electron pairs is achieved, and the complex is formed. This coordination property has a wide range of uses in the field of catalysis. It can construct metal-organic complex catalysts and change the electronic structure and spatial configuration of the catalyst, thereby improving the activity and selectivity of the catalytic reaction.
    Stability
    The compound has certain stability under general conditions. The conjugated structure of the pyridine ring gives it high stability, and the presence of triethylamino groups also contributes to its stability. In case of extreme conditions such as high temperature, strong oxidants or strong acids and bases, its structure may be damaged. For example, strong oxidants can oxidize the pyridine ring, altering its chemical structure and properties.
    What are the precautions for storing and transporting 3,5-bis (trifluoromethyl) iodobenzene?
    3% 2C5 -bis (triethylamino) pyridine in storage and transportation, many matters need to be paid attention to.
    When storing, the first heavy environment. It should be placed in a cool, dry and well-ventilated place. This is because if it is in a high temperature, humid place, or causes changes in properties, it will affect the quality. High temperature can promote its chemical reaction, and moisture can easily cause it to deteriorate. And it needs to be kept away from fire and heat sources. Because it has certain chemical activity, it may be dangerous to encounter open flames, hot topics.
    Furthermore, it should be stored separately from oxidants, acids, etc. Due to the special chemical properties of 3% 2C5-bis (triethylamino) pyridine, it encounters with oxidants or undergoes violent oxidation reactions; contact with acids may also occur chemical reactions, resulting in material damage and even safety accidents.
    Storage containers should not be ignored. A well-sealed container should be used to prevent it from evaporating or reacting with components in the air. And the container material should be compatible with 3% 2C5-bis (triethylamino) pyridine, and no corrosion and other reactions should occur to avoid material leakage caused by container damage.
    When transporting, the packaging must be solid. Appropriate packaging materials and methods should be used in accordance with relevant regulations to ensure that the packaging is not damaged during transportation. When loading and unloading, the operator should pack lightly to avoid damage to the package caused by brutal operation and cause leakage.
    Transportation vehicles are also required. It should be clean and dry, and there should be no residual substances that can react with 3% 2C5-bis (triethylamino) pyridine. And the transportation process should be protected from exposure to the sun, rain, and avoid the influence of high temperature and humid environment.
    The transportation process should also strictly follow relevant regulations and operating procedures, and be equipped with necessary emergency treatment equipment and protective supplies for emergencies. In this way, the storage and transportation of 3% 2C5-bis (triethylamino) pyridine should be guaranteed to be safe and stable.