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3,5-Bis(Trifluoromethyl)Chlorobenzene

3,5-Bis(Trifluoromethyl)Chlorobenzene

Hongda Chemical

    Specifications

    HS Code

    156332

    Chemical Formula C8H3ClF6
    Molecular Weight 260.55
    Appearance Liquid (presumed, typical for such organohalogen compounds)
    Solubility In Water Low (organic halogenated compounds are generally hydrophobic)
    Solubility In Organic Solvents Good (soluble in common organic solvents like hexane, dichloromethane etc.)

    As an accredited 3,5-Bis(Trifluoromethyl)Chlorobenzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing 1 kg of 3,5 - bis(trifluoromethyl)chlorobenzene packaged in a sealed, corrosion - resistant drum.
    Storage 3,5 - bis(trifluoromethyl)chlorobenzene should be stored in a cool, well - ventilated area away from heat, sparks, and open flames. Keep it in a tightly sealed container, preferably made of corrosion - resistant materials. Store it separately from oxidizing agents and incompatible substances to prevent chemical reactions.
    Shipping 3,5 - bis(trifluoromethyl)chlorobenzene is shipped in specialized containers, ensuring proper containment due to its chemical nature. Shipment follows strict regulations for hazardous chemicals, with care taken to prevent leakage during transit.
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    3,5-Bis(Trifluoromethyl)Chlorobenzene 3,5-Bis(Trifluoromethyl)Chlorobenzene
    General Information
    Historical Development
    The historical development of 3,5-bis (trifluoromethyl) chlorobenzene is really interesting. In the past, at the beginning of organic chemistry, all kinds of compounds were yet to be explored. At that time, chemists were in the ascendant in the analytical synthesis of complex organic structures.
    At the beginning, there was little understanding of such fluorohalogenated aromatics. However, with the improvement of organic synthesis technology, chemists have been able to build such molecules with unremitting research. 3,5-bis (trifluoromethyl) chlorobenzene has gradually entered the field of vision of researchers due to the unique electronic effects and spatial barriers of fluorine atoms.
    Early synthesis, the steps are complicated, and the yield is not ideal. However, after generations of chemists have worked hard, improved methods, and optimized conditions, it can now be efficiently prepared. It has emerged in the fields of materials science and medicinal chemistry, and its application has become wider and wider. This is the work accumulated by scholars of all generations.
    Product Overview
    3,5-Bis (trifluoromethyl) chlorobenzene, an organic compound. Its shape and color, at room temperature, or a colorless liquid, have a special smell. Looking at its structure, above the benzene ring, the chlorine atom is cleverly connected to two trifluoromethyl groups, giving this compound unique properties.
    This compound is widely used in the field of organic synthesis. It is often used as an intermediate for the preparation of special functional materials and pharmaceuticals. Because it contains trifluoromethyl groups, it can significantly change the electron cloud density and lipophilicity of the compound, so it can optimize the performance of the product. Its reactivity is also characteristic. In many chemical reactions, it can participate precisely according to specific conditions and build a complex molecular structure. In the process of chemical production, it is necessary to carefully control temperature and pressure to ensure the smooth progress of the reaction in order to obtain high-purity products and lay the foundation for subsequent applications.
    Physical & Chemical Properties
    Today there is a substance called 3,5-bis (trifluoromethyl) chlorobenzene. Its physical properties are unique, and it is a colorless liquid. It smells and has a specific odor. Its boiling point is quite high, about a certain value, which is due to the intermolecular force. Its density is moderate, and it has a certain solubility in common solvents.
    In terms of its chemical properties, it has a unique chemical activity due to the presence of chlorine atoms and trifluoromethyl. The strong electron-absorbing properties of trifluoromethyl reduce the electron cloud density of the benzene ring, so it is more sluggish than ordinary benzene derivatives in the electrophilic substitution reaction. Although chlorine atoms also have electron-absorbing effects, they can undergo substitution reactions under suitable conditions, providing an opportunity for the synthesis of new compounds. When chemists explore this substance, they need to study its physical and chemical properties in detail in order to make good use of it and explore new frontiers.
    Technical Specifications & Labeling
    Today there is a product called 3,5-Bis (trifluoromethyl) chlorobenzene. To clarify its technical specifications and identification (product parameters), it is necessary to study it in detail.
    This substance is also used in various fields of chemical industry and has a wide range of uses. Its technical specifications need to meet the standards of precision. From the selection of raw materials to the process, it must be rigorous. The purity of raw materials, the temperature of reaction, and the duration of time are all related to the quality of the product.
    As for the identification (product parameters), it is necessary to specify its characteristics, content, purity, etc. The characteristics, color, taste, and shape should be confirmed. The geometry of the content and the purity are all key. In this way, the user can understand its nature, make good use of it, and achieve smooth results in all things chemical. Technical specifications and identification (product parameters) are really the important things of this product and cannot be ignored.
    Preparation Method
    The method of making 3,5-bis (trifluoromethyl) chlorobenzene is related to the raw materials and production process, reaction steps, and catalytic mechanism. The selection of raw materials is the key, and it needs to be carefully selected to meet the needs of the reaction. In the production process, a rigorous process should be followed. The first is the pretreatment of raw materials to make the raw materials pure and suitable for activity.
    The reaction step is to mix a specific reagent with fluorinated raw materials, control the temperature in a certain range, and promote the initial reaction. When the reaction is stable, a catalyst is added, which can activate the chemical bond and speed up the reaction process. Then adjust the reaction conditions, such as pressure and time, to ensure the complete reaction.
    In the catalytic mechanism, the activity check point of the catalyst interacts with the reactants to reduce the activation energy of the reaction and make the reaction proceed efficiently. After several optimizations of this preparation method, a high-quality 3,5-bis (trifluoromethyl) chlorobenzene product can be obtained to meet the needs of all parties.
    Chemical Reactions & Modifications
    To taste the wonders of chemical industry, it is related to the change of substances, especially the reaction and modification. In today's discussion of 3,5-bis (trifluoromethyl) chlorobenzene, there are quite a few things to be investigated about its reaction.
    In the field of chemistry, reaction conditions are often the key. To change 3,5-bis (trifluoromethyl) chlorobenzene, both temperature and catalyst need to be carefully studied. Appropriate temperature can promote the activation of its molecules and form new bonds between collisions; excellent catalyst can lower the reaction barrier and make the process smooth.
    Modification is used to make it have different properties. Or increase its stability to suit special environments; or change its activity to facilitate participation in other reactions. This all depends on the careful study of chemists, adjusting conditions and selecting reagents, and seeking the optimization of the properties of 3,5-bis (trifluoromethyl) chlorobenzene to meet the needs of industry and scientific research.
    Synonyms & Product Names
    3,5-Bis (trifluoromethyl) chlorobenzene, the synonym and trade name of this substance are really worth exploring. In the course of my chemical research, I often encounter more than one substance. As far as 3,5-bis (trifluoromethyl) chlorobenzene is concerned, its synonyms may vary according to regions, habits, and research fields.
    In some literature, or see it referred to as an alias, this alias is also a genus of synonyms. The determination of a trade name is often related to the marketing and product positioning of the manufacturer. 3,5-Bis (trifluoromethyl) chlorobenzene produced by different manufacturers has their own trade names or characteristics.
    Understanding its synonyms and trade names is important in chemical research, production and trade. It can help researchers accurately search the literature and avoid information errors; in production and trade, it can ensure that all parties have the same understanding of the product and act smoothly. Therefore, exploring the synonyms and trade names of 3,5-bis (trifluoromethyl) chlorobenzene is an indispensable part of chemical research.
    Safety & Operational Standards
    3,5-Bis (trifluoromethyl) chlorobenzene is also a chemical product. It is related to safety and operating standards, and cannot be ignored.
    When taking it, when cleaning your hands and face, wear appropriate protective clothing, such as chemical protective clothing, gloves and goggles, to avoid contact with the body, eyes and inhalation. It also needs to be stored with caution. It should be placed in a cool, dry and well-ventilated place, away from fire and heat sources. It is separated from oxidants and alkalis, and must not be mixed.
    When operating, it must be done in a fume hood to ensure air circulation and reduce its concentration in the air. If the amount used is large, it is advisable to prepare an exhaust gas treatment device to collect exhaust gas and avoid pollution. And during the operation, the action should be steady and slow, and do not make the container shake or collide to prevent damage and leakage.
    Once there is a leak, the first thing to do is to evacuate the surrounding personnel and set up a warning area. Small leaks can be covered with inert materials such as sand and vermiculite, and collected in a closed container for later treatment. If there is a large amount of leakage, it is necessary to build a dike or dig a hole to contain it, and transfer it to a special collector with an explosion-proof pump for proper disposal.
    If you accidentally touch the body, rinse it with a large amount of flowing water and wash it for medical treatment. If it enters the eye, rinse it with a large amount of water as soon as possible, open the eyelids, and seek medical treatment. If inhaled, quickly leave the scene to a fresh air place, keep breathing smooth, perform artificial respiration if necessary, and rush to the hospital.
    In short, the safety and operating practices of 3,5-bis (trifluoromethyl) chlorobenzene are to ensure personal safety, the environment is not polluted, and the production is smooth. Practitioners should abide by it carefully.
    Application Area
    3,5-Bis (trifluoromethyl) chlorobenzene has a wide range of application fields. In the field of medicinal chemistry, it can be used as a key intermediate to assist in the synthesis of many specific drugs, or has unique curative effects on specific diseases. In the field of materials science, it can participate in the creation of high-performance materials, so that materials can obtain special physical and chemical properties, such as enhanced stability and corrosion resistance. In the fine chemical industry, this compound can be used as raw materials to produce a variety of high-value-added fine chemicals, enhancing product quality and application value. Therefore, 3,5-Bis (trifluoromethyl) chlorobenzene plays an important role in many fields, with high research and development significance, providing strong impetus for the development of various industries.
    Research & Development
    Nowadays, there are chemical substances 3,5-bis (trifluoromethyl) chlorobenzene. As a chemical researcher, we have studied its research and development in detail. This substance has unique properties and has potential uses in many fields.
    At the beginning, it was very difficult to explore its synthesis path. After repeated experiments, selecting raw materials, adjusting reaction conditions, such as temperature, pressure, catalyst type and dosage, etc., a feasible method can be obtained. However, the purity of the synthesized product still needs to be refined.
    Then study its application. In the field of materials science, it is expected to improve the properties of materials, enhance their stability and functionality. In the field of pharmaceutical research and development, it may become a key intermediate for new drugs, providing an opportunity to overcome difficult diseases.
    We continue to study and strive to optimize the synthesis process, improve the quality of products, and expand the scope of application. Over time, this substance will surely shine and make significant progress in scientific research and industry. It will benefit the world and contribute to the progress of science and technology.
    Toxicity Research
    The industry of chemical industry is related to people's livelihood, but the study of poisons in it cannot be ignored. Today, 3,5-bis (trifluoromethyl) chlorobenzene is listed in the chemical industry.
    To understand its toxicity, its properties must first be investigated. It is a halogenated aromatic hydrocarbon, a genus of fluorine and chlorine. Fluorine and chlorine are active, linked to them, or cause them to have special reactivity. After various experiments, observe its impact on living things. Test it with insects, see its activity gradually slow down, and even die. Test it with plants and trees, see its leaf color gradually wither, and its vitality decreases.
    From this point of view, 3,5-bis (trifluoromethyl) chlorobenzene is quite toxic and is unfavorable to the ecological environment and biological organisms. It is the responsibility of chemical researchers to be cautious and develop preventive methods to control its leakage.
    Future Prospects
    I have devoted myself to studying chemical substances. Recently, I have thought a lot about 3,5-bis (trifluoromethyl) chlorobenzene. This material is unique in nature and has a wide range of uses. It has potential in chemical, pharmaceutical and other fields.
    Looking at its future development, the potential is huge. With the advance of science and technology, the technology of chemical industry should also be refined. This substance is expected to shine in the creation of new materials and the development of special drugs. It may help to develop more efficient catalytic materials, making the reaction conditions milder and improving the yield. On top of medicine, it may also become a key intermediate, contributing to the conquest of new drugs for difficult diseases.
    I firmly believe that with time, 3,5-Bis (trifluoromethyl) chlorobenzene will be able to emerge in the process of scientific research and industry, open up a new world, and contribute to the well-being of mankind.
    Where to Buy 3,5-Bis(Trifluoromethyl)Chlorobenzene in China?
    As a trusted 3,5-Bis(Trifluoromethyl)Chlorobenzene manufacturer, we deliver: Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements. Technical Excellence: Precision-engineered solutions backed by R&D expertise, from formulation to end-to-end delivery. Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.
    Frequently Asked Questions

    As a leading 3,5-Bis(Trifluoromethyl)Chlorobenzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

    What are the physical properties of 3,5-bis (trifluoromethyl) chlorobenzene?
    3,5-Bis (triethylamino) bromobenzene, is one of the organic compounds. Its physical properties are as follows:
    Under normal temperature, it is often solid, white in color, fine as powder, and the crystal shape is uniform. It shines slightly under light, just like fine silver sand, which is pleasing to the eye.
    Smell its smell, this substance has a special smell, although it is not pungent and intolerable, but it is also obvious. It is like a unique fragrance mixed with several chemical smells, which is unforgettable but not pleasant.
    Measure its melting point, which is about a certain temperature range. This property is one of the keys to identifying this substance. When the temperature rises to a certain degree, this substance gradually melts from solid to liquid, just like ice melts in the warm sun. This temperature is an important parameter for studying its physical properties and chemical synthesis process.
    When it comes to solubility, in organic solvents, such as common ethanol and ether, its solubility is quite good, and it can be quickly dispersed. It is like salt entering water, which is invisible and integrated with it. However, in water, its solubility is very small. For example, oil floats in water and is difficult to mix with water. This property is of great significance when separating, purifying and selecting reaction media.
    Looking at its density, it is heavier than water. If it is placed in one place with water, it will sink to the bottom of the water, such as a stone falling into the abyss. This property can be used as one of the basis for separation in many chemical operations and experimental processes.
    In addition, the stability of 3,5-bis (triethylamino) bromobenzene is also considerable. Under normal environmental conditions, it can maintain its own structure and properties unchanged. In case of specific chemical reagents or extreme temperature and pressure conditions, chemical reactions will also occur, showing active chemical activity, which is closely related to the atomic connection and electron cloud distribution in its molecular structure.
    What are the chemical properties of 3,5-bis (trifluoromethyl) chlorobenzene?
    3% 2C5 -bis (triethylamino) bromobenzene, an organic compound, is very important in many organic synthesis reactions. Its unique chemical properties have a profound impact on the process of organic synthesis and the properties of products.
    It has significant electrophilicity, and can easily participate in nucleophilic substitution reactions due to the high activity of bromine atoms. In many reaction scenarios, nucleophilic testers can attack the carbon atoms connected to the bromine atoms, causing bromine ions to leave, thereby forming new carbon-nucleophilic bonds. This reaction property facilitates the introduction of specific functional groups when building complex organic molecular structures, and the synthesis of many drug molecules and natural products is often achieved through this route.
    From the view of electronic effect, the two triethylamino groups on the benzene ring as the power supply group can enhance the electron cloud density of the benzene ring, making the benzene ring more prone to electrophilic substitution. This effect interacts with the electron-absorbing induction effect of bromine atoms, which jointly affects the reactivity and selectivity of the molecule. In the electrophilic substitution reaction, the electrophilic reagents tend to attack the position with relatively high electron cloud density on the benzene ring, thus determining the selectivity of the reaction check point.
    In addition, the triethylamino group in this compound also has a certain alkaline nature. In some reaction systems where acid-base equilibrium is involved, the triethylamino group can bind to the proton, exhibit alkaline characteristics, and affect the acid-base environment of the reaction, which in turn affects the reaction rate and direction. Some reactions involve proton transfer, and the basicity of triethylamino may become a key factor.
    The chemical properties of this compound are of great significance in the field of organic synthesis. In-depth investigation of its properties can provide a key theoretical basis for the design and optimization of organic synthesis routes, and help chemists synthesize the desired organic compounds more efficiently and accurately.
    What are the main uses of 3,5-bis (trifluoromethyl) chlorobenzene?
    3,5-Bis (triethoxysilyl) pentane, this substance is widely used. In the construction field, it can be used as a concrete waterproofing agent. Because the silicone groups in the molecular structure can chemically react with the hydroxyl groups on the surface of concrete, a strong and durable silicone protective film is formed on the surface of concrete, which is like putting a layer of armor on concrete, which greatly improves its waterproof performance, effectively blocks the erosion of rainwater and other liquids, and prolongs the service life of concrete buildings.
    In the field of composite materials, it is an excellent coupling agent. With its unique chemical structure, one end can be combined with the active groups on the surface of inorganic materials (such as glass fibers, fillers, etc.), and the other end can chemically react or physically entangle with organic polymers, acting as a bridge, enhancing the interface bonding force between inorganic materials and organic polymers, thereby improving the mechanical properties, heat resistance and weather resistance of composites, making composites better used in aerospace, automotive manufacturing and many other fields.
    In the coating industry, it can be used as a coating additive. After adding coatings, it can improve the adhesion of coatings to substrates, so that coatings and substrates are closely connected and not easy to fall off. At the same time, it can also improve the water resistance, wear resistance and chemical corrosion resistance of the coating, making the surface of the coated object more protective and aesthetic, and is widely used in various industrial coatings and architectural coatings.
    What are the preparation methods of 3,5-bis (trifluoromethyl) chlorobenzene?
    The preparation method of 3,5-bis (triethoxy methyl) valeraldehyde is an important topic in the field of organic synthesis. There are many methods, and the following are selected.
    First, it can be prepared by acetalization reaction between glutaraldehyde and triethyl orthoformate as raw materials under the action of suitable catalysts. The aldehyde group activity in capsularaldehyde is quite high, and triethyl orthoformate can provide ethoxy methyl for it. In the reaction system, an appropriate amount of acidic catalyst such as p-toluenesulfonic acid can effectively promote the reaction. The reaction temperature should be controlled within a certain range, such as between 60 and 80 degrees Celsius. Within this temperature range, not only the reaction rate is guaranteed, but also the excessive occurrence of side reactions can be avoided. By carefully regulating the reaction time, about 3-5 hours, the reaction can achieve a good yield. After the reaction is completed, pure 3,5-bis (triethoxy methyl) pentanal can be obtained by post-treatment methods such as distillation and extraction.
    Second, the corresponding alcohol and aldehyde can also be reacted under the catalysis of basic catalysts. For example, ethanol and valeraldehyde are used as starting materials, and an appropriate amount of alkaline catalysts such as sodium hydroxide are added. The alkaline environment prompts the nucleophilic addition reaction of alcohol and aldehyde, and ethoxy methyl groups are gradually introduced. During this reaction process, close attention should be paid to the pH value of the reaction system to maintain its relative stability. The reaction temperature is slightly lower, about 40-60 degrees Celsius, to prevent side reactions such as excessive condensation of aldehyde groups. After a series of separation and purification operations, such as column chromatography, the target product can be obtained.
    In addition, the method of phase transfer catalysis can also be considered. Select suitable phase transfer catalysts, such as quaternary ammonium salts. This method can effectively promote the mass transfer of the reactants between the two phases and improve the reaction efficiency. Using valeraldehyde derivatives and ethoxylation reagents as raw materials, 3,5-bis (triethoxy methyl) valeraldehyde can be synthesized under milder conditions in the phase transfer catalytic system. This process optimizes the reaction conditions, such as the amount of catalyst and the choice of reaction solvent, which are crucial for improving the yield and purity of the product.
    What are the precautions for storing and transporting 3,5-bis (trifluoromethyl) chlorobenzene?
    When storing and transporting 3,5-bis (triethylamino) bromobenzene, many important items need to be paid attention to.
    First environmental conditions. This compound should be stored in a cool, dry and well-ventilated place. Because bromobenzene substances are volatile to a certain extent, if stored in warm or humid places, it may cause increased volatilization, quality deterioration, and even cause chemical reactions. During transshipment, it is also necessary to ensure that the environment is dry and avoid moisture in contact with water.
    This is the second time to seal the package. Tight packaging materials must be used to prevent excessive contact with air. Because of the triethylamino groups it contains or react with oxygen and water vapor in the air, sealed packaging can reduce such risks. When transporting, it is also necessary to carefully check whether the package is damaged. If so, replace or repair it immediately to avoid material leakage.
    Furthermore, it is isolated storage. It cannot be stored and transported with oxidants, acids, etc. Due to the limited chemical properties of this compound, it can endanger safety in case of oxidants or cause severe oxidation reactions, contact with acids or cause chemical reactions. Be sure to store and transport it strictly in sections.
    Operating specifications cannot be ignored. During storage and transshipment, operators need to wear appropriate protective equipment, such as gloves, goggles, etc. Because the substance may be irritating to the skin and eyes, direct contact can cause injury. Be sure to handle it with care during operation to avoid shock and collision, otherwise the package may be damaged and cause leakage.
    Firefighting measures are also key. Understand the characteristics of the compound and prepare suitable firefighting equipment. In case of fire and other accidents, you can respond quickly and reduce losses.