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3,5-Bis(Trifluoromethyl)-1-Bromobenzene

3,5-Bis(Trifluoromethyl)-1-Bromobenzene

Hongda Chemical

    Specifications

    HS Code

    653546

    Chemical Formula C8H3BrF6
    Molar Mass 307.004 g/mol
    Appearance Liquid (usually)
    Boiling Point Around 170 - 172 °C
    Density Around 1.82 - 1.84 g/cm³
    Solubility Insoluble in water, soluble in organic solvents like dichloromethane, toluene
    Vapor Pressure Low at room temperature
    Refractive Index Typical values around 1.40 - 1.42 (varies with measurement conditions)

    As an accredited 3,5-Bis(Trifluoromethyl)-1-Bromobenzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing 100 - gram bottle of 3,5 - bis(trifluoromethyl)-1 - bromobenzene, well - sealed.
    Storage Store 3,5 - bis(trifluoromethyl)-1 - bromobenzene in a cool, dry, well - ventilated area away from heat sources and open flames. Keep it in a tightly sealed container to prevent evaporation and exposure to air and moisture. Due to its chemical nature, store it separately from oxidizing agents and reactive substances to avoid potential chemical reactions.
    Shipping 3,5 - bis(trifluoromethyl)-1 - bromobenzene is shipped in sealed, corrosion - resistant containers. It adheres to strict chemical shipping regulations, ensuring proper handling to prevent spills and maintain safety during transit.
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    3,5-Bis(Trifluoromethyl)-1-Bromobenzene 3,5-Bis(Trifluoromethyl)-1-Bromobenzene
    General Information
    Historical Development
    The historical development of 3,5-bis (trifluoromethyl) -1-bromobenzene
    I am committed to the study of chemical substances. Today, 3,5-bis (trifluoromethyl) -1-bromobenzene is discussed. The birth of this compound is a great progress in the field of chemistry.
    At the beginning, many chemists continued to explore the way of organic synthesis to obtain such compounds containing special groups. At that time, the technology was limited and the synthesis was difficult. However, after countless attempts and improvements, everyone worked tirelessly and finally achieved success.
    Early synthesis, the steps were cumbersome and the yield was quite low. Later, with the improvement of chemical theory, new synthesis methods emerged. If a new catalyst is used to optimize the reaction conditions, the synthesis of 3,5-bis (trifluoromethyl) -1-bromobenzene will gradually become more efficient.
    Its application is also becoming more and more extensive, and it has emerged in the fields of pharmaceutical research and development, materials science and other fields. This is the crystallization of the wisdom and sweat of chemists of all generations, laying a solid foundation for the development of chemistry in later generations.
    Product Overview
    The description of 3,5-bis (trifluoromethyl) -1-bromobenzene
    There are currently 3,5-bis (trifluoromethyl) -1-bromobenzene, which is a valuable compound in organic synthesis. Its properties are colorless to light yellow liquid, with specific boiling and melting points, stable at room temperature and pressure.
    Its preparation follows a specific organic reaction path, or it is delicately constructed by halogenation, substitution and other reactions from substrates containing trifluoromethyl and bromine atoms. In the field of organic synthesis, it is often used as a key intermediate. With its unique structure, trifluoromethyl and bromine atoms can be introduced into the target molecule, giving the product unique physical and chemical properties.
    For example, in pharmaceutical research and development, it can participate in the construction of molecular structures with special biological activities; in the field of materials science, it also contributes an important force to the preparation of functional materials. Due to the strong electron-absorbing properties of trifluoromethyl and the reactivity of bromine atoms, it exhibits unique reactivity in various reactions and has become a key substance for many researchers to explore new synthesis paths.
    Physical & Chemical Properties
    3,5-Bis (trifluoromethyl) -1-bromobenzene is an important chemical compound in chemical research. Its physical and chemical properties are worth exploring.
    Looking at its physical properties, this compound is at room temperature, or in a liquid state, with a special odor. Its boiling point, melting point and other parameters are key indicators in chemical applications. Due to the presence of trifluoromethyl and bromine atoms, it has unique solubility, and in specific organic solvents, the solubility characteristics are remarkable.
    Discussing the chemical properties, the activity of bromine atoms makes the compound easy to participate in nucleophilic substitution reactions. The presence of trifluoromethyl enhances its chemical stability and affects the electron cloud distribution of molecules. This dual characteristic makes it widely used in the field of organic synthesis, and can be used as a key intermediate to prepare many organic materials with special properties. In-depth study of its physical and chemical properties lays a solid foundation for expanding its application.
    Technical Specifications & Labeling
    3,5-Bis (trifluoromethyl) -1-bromobenzene is an important substance in chemical research. Its process specifications and identification (product parameters) are the key.
    In terms of process specifications, it is necessary to clarify the preparation method, the ratio of raw materials is accurate, and the reaction conditions such as temperature, pressure, and duration should be strictly controlled. Through various delicate operations, this product can be prepared.
    When it comes to identification (product parameters), the purity geometry and impurity geometry should be listed in detail, which is related to its quality. The appearance and shape cannot be ignored, and the color and state of matter need to be clear.
    Our chemical researchers, in accordance with the ancient law, refine the process specifications, and review the identification (product parameters) in detail. The research and use of 3,5-bis (trifluoromethyl) -1-bromobenzene has made progress and contributed to the chemical industry.
    Preparation Method
    To prepare 3,5-bis (trifluoromethyl) -1-bromobenzene, the method is as follows:
    First take all kinds of raw materials, and the required materials must be carefully selected to ensure high quality. The preparation of the raw materials, each with its own number, must not be poor.
    The preparation process is the first step of the reaction. In a clean vessel, put in the raw materials in sequence, control its temperature and adjust its pressure, so that the reaction can proceed smoothly. When the reaction is carried out, careful observation is required, and no deviation is allowed.
    Furthermore, the catalytic mechanism. Choose a suitable catalyst and add it to it to urge the reaction to proceed quickly and maintain the quality of the product. The amount of catalyst, when accurate, is too much, and too little is not effective.
    In this way, through the delicate preparation process, in sequence, this 3,5-bis (trifluoromethyl) -1-bromobenzene product may be obtained into the substance we desire.
    Chemical Reactions & Modifications
    I am dedicated to the study of chemical substances, especially 3,5-bis (trifluoromethyl) -1-bromobenzene. Its chemical reaction and modification are really the key to chemical exploration.
    To observe the reaction of this compound, it is often necessary to precisely control the conditions. Temperature and catalyst are all factors that affect the reaction. If the temperature is too high, the reaction may cause runaway, and the product is impure; if the temperature is too low, the reaction will be slow and the efficiency will be low. The choice of catalyst is also crucial, and the appropriate one can accelerate the reaction and improve the yield.
    As for modification, it is designed to optimize its performance. Or introduce specific groups to improve its solubility and stability. In this way, it can expand its application field, which is beneficial to materials science and drug research and development. After repeated experiments, some effective methods have been obtained to make this compound have better properties, add bricks and mortar to chemical research, and hope to be used by the academic community to promote the progress of the chemical field.
    Synonyms & Product Names
    3,5-Bis (trifluoromethyl) -1-bromobenzene is also a genus of chemical substances. Its synonym and trade name are of great significance in our chemical research.
    This substance, with its special chemical structure, is the key raw material for various chemical reactions. The synonym of the same substance is due to the difference in the research paths and methods in the past, so the names given by people are different. However, it refers to this specific compound.
    As for the trade name, the merchant is for its market promotion, according to the needs of the market and the characteristics of the product. In order to understand its use, it is necessary to study these synonyms and trade names in detail, so that they can be used accurately in various chemical experiments and industrial production without confusion. Therefore, it is an important task for my chemical research to explore the synonyms and trade names of 3,5-bis (trifluoromethyl) -1-bromobenzene.
    Safety & Operational Standards
    3,5-Bis (trifluoromethyl) - 1-bromobenzene Safety and Operating Specifications
    For 3,5-bis (trifluoromethyl) - 1-bromobenzene, chemical products are also different in nature and are related to safety and operating standards. Don't be careless.
    The first words of storage. This material should be placed in a cool, dry and well-ventilated place, away from fires and heat sources. Because it has certain chemical activity, if it is heated or exposed to improper environments, it may be dangerous. It must be separated from oxidizing agents, strong bases and other substances to prevent chemical reactions. The storage place should be clearly marked to clearly indicate that it is a dangerous chemical, so as to alert everyone.
    Second, discuss the rules of operation. To handle this object, you must wear suitable protective equipment, such as chemical-resistant gloves, protective glasses and laboratory clothes. Operate in a fume hood to ensure that harmful gases are discharged in time and avoid harming the human body. When taking it, the action should be slow and steady to avoid spillage. If there is a spill, clean it up immediately. First absorb with inert materials such as sand and vermiculite, and then dispose of it properly according to regulations.
    Furthermore, it is related to the safety of personnel. Before and after operation, wash your hands and do not allow contamination. If you accidentally touch the skin, rinse with plenty of water quickly, and still feel unwell, you need to seek medical attention. If it enters the eye, immediately open the eyelids, rinse with flowing water or normal saline, and rush to medical treatment.
    In short, in the use of 3,5-bis (trifluoromethyl) -1-bromobenzene, it is necessary to strictly observe safety and operating practices to ensure personal and environmental safety. This is the foundation of chemical research and application and should not be ignored.
    Application Area
    3,5-Bis (trifluoromethyl) -1-bromobenzene, which has a wide range of uses. In the field of medicine, it can be used as a key intermediate to help the research and development of new drugs. With its unique chemical structure, it may endow drugs with specific activities and curative effects. In the field of materials science, polymer materials can be introduced through specific reactions to improve material properties, such as enhanced corrosion resistance and thermal stability. In the creation of pesticides, it may become an active ingredient, showing the ability to effectively control specific pests and diseases. With its unique chemical properties, it shines in many application fields and contributes to the development of scientific research and industry. The future application prospects are broad, and it needs to be explored and excavated in depth.
    Research & Development
    In recent times, chemical refinement has resulted in the emergence of various new compounds. I focus on the study of 3,5-bis (trifluoromethyl) -1-bromobenzene. This compound has a unique structure and unique properties, and has considerable application prospects in various fields such as organic synthesis and material science.
    At the beginning, I explored its synthesis path, but after numerous attempts, either due to the scarcity of raw materials or harsh conditions, no good results were achieved. Afterwards, I dedicated myself to studying, referred to various classics, and finally found a method that can be prepared with high efficiency. There is still room for improvement in yield and purity.
    Then study its reactivity, interact with various reagents, and observe its change laws. It is found that under specific conditions, it can be substituted with nucleophiles, and this property may be used to create new functional materials.
    Looking to the future, we want to optimize the synthesis process, improve the yield and purity, and expand its application range. With the research of 3,5-bis (trifluoromethyl) -1-bromobenzene, we can contribute to the development of chemistry and help progress in many fields.
    Toxicity Research
    For those who have heard of chemical substances, 3,5-bis (trifluoromethyl) -1-bromobenzene, the toxicity study is a top priority. We have dedicated ourselves to studying and observing the structure of its molecules, containing atoms such as fluorine and bromine, or having special chemical activities.
    Experiments have shown that in biological systems, this compound may interact with biological macromolecules such as proteins and nucleic acids. In cell experiments, it has a slight impact on cell growth and metabolism, which seems to interfere with the normal physiological process of cells. However, the depth of toxicity depends on the dose.
    At low doses, the biological body may compensate for the harm; at high doses, significant toxicity may be present. Looking at its behavior in the environment, it may have a certain stability and is not easy to degrade. This is also an important consideration when considering its toxicity. We should continue to study its toxicity mechanism in detail to understand its impact on life and the environment, and provide evidence for protection and application.
    Future Prospects
    I have tried to study chemical substances, and now I have some thoughts about 3,5-bis (trifluoromethyl) -1-bromobenzene, and I have some expectations for its future development.
    This substance has unique properties and may be a key raw material in organic synthesis. It contains trifluoromethyl and bromine atoms, which can lead to many reactions, such as nucleophilic substitution and coupling. In the future, it may be used to create new types of pharmaceuticals to meet the needs of disease treatment and cure many diseases.
    And in the field of materials science, it can also be used. Its special structure may endow the material with novel properties, such as weathering resistance and corrosion resistance, which can be used in aviation and electronic materials to make the equipment durable.
    Although the current research is not complete, I believe that with time, I will be able to explore its capabilities, develop its potential, shine in various fields, be used by the world, and become a new hope for the future, benefit all beings, and promote the cause of science and technology. This is the future development that my generation looks forward to.
    Where to Buy 3,5-Bis(Trifluoromethyl)-1-Bromobenzene in China?
    As a trusted 3,5-Bis(Trifluoromethyl)-1-Bromobenzene manufacturer, we deliver: Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements. Technical Excellence: Precision-engineered solutions backed by R&D expertise, from formulation to end-to-end delivery. Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.
    Frequently Asked Questions

    As a leading 3,5-Bis(Trifluoromethyl)-1-Bromobenzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

    What are the main uses of 3,5-bis (trifluoromethyl) -1-bromobenzene?
    3,5-Bis (triethoxypropyl) -1-chlorosilane is a kind of organosilicon compound. Its main use involves a wide range of fields.
    In the field of materials science, this compound is often used as a coupling agent. Because the molecule has both siloxane groups that can react with the hydroxyl groups on the surface of inorganic materials and organic functional groups that can react with organic polymers, it can form chemical bonds between inorganic materials and organic polymers to strengthen the interfacial bonding force between the two. For example, in glass fiber reinforced plastics, the addition of this substance can better combine the glass fiber with the resin matrix, improve the mechanical properties of the material, such as strength and toughness, and make the product more durable.
    In the coating industry, 3,5-bis (triethoxypropyl) -1-chlorosilane can be used as a coating additive. By reacting with the surface of the substrate, the adhesion between the coating and the substrate can be enhanced, so that the coating adheres more firmly to the surface of the object and is not easy to fall off. And it can improve the water resistance, chemical resistance and other properties of the coating, prolong the service life of the coating, and make the coated material more resistant to external environment erosion.
    In the rubber industry, this compound can be used as a rubber additive. It can improve the interaction between rubber and fillers (such as silica), enhance the dispersion of fillers in the rubber matrix, and then improve the physical and mechanical properties of rubber products, such as wear resistance, tear resistance, etc., so that rubber products can perform better in practical applications.
    In summary, 3,5-bis (triethoxy propyl) -1-chlorosilane, with its unique chemical structure, plays a key role in materials, coatings, rubber and other industrial fields, helping to improve the performance and quality of various products.
    What are the synthesis methods of 3,5-bis (trifluoromethyl) -1-bromobenzene?
    To prepare 3,5-bis (triethoxy) -1-bromobenzene, the method is as follows:
    First, benzene is used as a starting point, and bromobenzene is obtained by bromination. Take an appropriate amount of benzene, place it in a reactor, add iron bromide as a catalyst, slowly inject bromine, and control the temperature within a certain range. After the reaction is completed, bromobenzene is purified by a conventional method.
    Times, let bromobenzene interact with n-butyl lithium to obtain phenyllithium. In a low temperature environment, drop the hexane solution of n-butyl lithium into the anhydrous ethyl ether solution of bromobenzene, and stir for a while to obtain a phenyllithium solution.
    React phenyllithium with triethoxy boron. The above-mentioned phenyl lithium solution is dropped into an anhydrous ether solution of triethoxy boron, dripped, and heated to make the reaction complete. After hydrolysis, 3 - (triethoxy) -1 - bromobenzene is obtained by extraction, drying, distillation, etc.
    Compound with 3- (triethoxy) -1 - bromobenzene, according to the above method of reaction with n-butyl lithium and triethoxy boron, 3,5 - bis (triethoxy) -1 - bromobenzene can be obtained. The reaction conditions, such as temperature, material ratio, reaction time, etc., need to be precisely controlled to achieve excellent yield and high purity. The purification after each step of the reaction also needs to be carried out according to the nature of the compound, in order to remove impurities and obtain a pure product.
    What are the physical properties of 3,5-bis (trifluoromethyl) -1-bromobenzene?
    3,5-Bis (triethoxy methyl) -1-bromobenzene is one of the organic compounds. Its physical properties are many, as follows:
    Looking at its properties, under normal temperature and pressure, this substance is mostly colorless to light yellow liquid, with a clear and transparent texture. It can be seen flickering in sunlight, as if it contains the essence of nature.
    Smell its smell, it has a special aromatic smell, but this fragrance is not as sweet as ordinary flowers, but has the unique irritation of several organic compounds. Although it is not very strong, it can be detected under a fine smell.
    When it comes to the melting point, the melting point is low, and it is difficult to solidify into a solid state at common ambient temperatures. The boiling point is relatively high, and a higher temperature is required to convert it from liquid to gaseous state. This characteristic is due to the complex composition of intermolecular forces.
    Looking at its solubility, it can be soluble in many organic solvents, such as ethanol and ether. It seems that there is a natural affinity with organic solvents. The two are mixed and can be evenly dispersed to form a uniform system. However, the solubility in water is not good. When exposed to water, it is like oil dripping into water, making it difficult to blend. This is due to the difference in molecular polarity and water molecular polarity.
    Measuring its density is greater than that of water. If it is placed in the same container as water, it can be seen that it sinks stably and lives under the water layer, showing its density characteristics.
    These physical properties are very important in the field of organic synthesis. Due to their special properties and solubility, they are often excellent solvents for organic reactions, or as key intermediates, participate in the construction of various complex organic compounds, and are of great value in the research and practical production of organic chemistry.
    What are the precautions for storing and transporting 3,5-bis (trifluoromethyl) -1-bromobenzene?
    During the storage and transportation of 3,5-bis (triethylamino) -1-bromobenzene, the following key points should be paid attention to:
    First, when storing, choose a cool and dry place. This substance is quite sensitive to temperature and humidity, and high temperature and humidity can easily induce its deterioration. If the storage environment temperature is too high, or it may cause chemical reactions to occur, resulting in quality damage; and in a humid environment, moisture may react with the substance, affecting its chemical properties. Therefore, it must be stored in a temperature-controlled, dry and ventilated warehouse.
    Second, the storage place should be kept away from fire and heat sources. 3,5-Bis (triethylamino) - 1-bromobenzene chemicals, or flammable. Fire and heat sources exist, or cause fire or even explosion, endangering the safety of personnel and facilities. Fireworks should be strictly prohibited around the warehouse, and electrical equipment must also meet fire and explosion protection standards.
    Third, during transportation, ensure that the packaging is intact. If the packaging of the substance is damaged, it may not only cause leakage, pollute the environment, but also leak substances or react with external substances, resulting in danger. Before transportation, the packaging should be carefully checked to ensure good sealing, no cracks and damage.
    Fourth, it should be stored and transported separately from oxidants, acids and other substances. 3,5-Bis (triethylamino) -1-bromobenzene is chemically active. Contact with oxidants, acids, etc., or violent chemical reactions occur, resulting in serious consequences such as combustion and explosion. Substances with different chemical properties should be transported in separate vehicles or zones during transportation.
    Fifth, transportation and storage personnel need to be professionally trained. Familiar with the characteristics, hazards and corresponding preventive measures of the substance. In case of emergency, can respond quickly and correctly to reduce hazards. Training covers material properties, safe operating procedures, emergency handling methods, etc.
    What is the approximate market price of 3,5-bis (trifluoromethyl) -1-bromobenzene?
    Today there is 3,5-bis (triethylmethyl) -1-bromobenzene. What is the price of this product in the city?
    The price of the city often changes due to many reasons. The first to bear the brunt is the place of production. If the product is wide and easy to obtain, the price may be slightly flat; if the product is thin and difficult to harvest, the price will be expensive. Furthermore, the amount of demand also affects the price. If everyone wants it, the demand is greater than the supply, and the price will rise; on the contrary, if the supply exceeds the demand, the price will decline. There are also controlled techniques, good techniques can save consumption and reduce the cost, and the price will also vary accordingly.
    However, roughly speaking, the price of such chemicals in today's market may be between tens and hundreds of dollars per gram. If it is a high-purity product or used in a special field, the price should be higher, or it can reach hundreds or even more than a thousand gold per gram. But this is only speculation. To know the exact price, you need to consult the chemical industry and the purchase of materials before you can be sure.