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3,4-Difluorobromobenzene

3,4-Difluorobromobenzene

Hongda Chemical

Specifications

HS Code

115435

Chemical Formula C6H3BrF2
Molar Mass 207.009 g/mol
Appearance Colorless to light yellow liquid
Boiling Point 158 - 160 °C
Density 1.697 g/cm³
Solubility In Water Insoluble
Solubility In Organic Solvents Soluble in common organic solvents like ethanol, ether
Flash Point 55 °C
Refractive Index 1.501 - 1.503

As an accredited 3,4-Difluorobromobenzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

Packing & Storage
Packing 500 - gram bottle of 3,4 - difluorobromobenzene with tight - sealed chemical - resistant packaging.
Storage 3,4 - difluorobromobenzene should be stored in a cool, well - ventilated area, away from heat sources and open flames. It should be kept in a tightly sealed container to prevent vapor leakage. Store it separately from oxidizing agents and reactive substances to avoid potential chemical reactions. Consider using corrosion - resistant containers as it may have some reactivity with certain materials.
Shipping 3,4 - difluorobromobenzene is shipped in well - sealed, corrosion - resistant containers. It must be handled with care as a hazardous chemical. Shipping follows strict regulations to ensure safety during transit, avoiding exposure and environmental risks.
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3,4-Difluorobromobenzene 3,4-Difluorobromobenzene
General Information
Historical Development
3,4-Difluorobromobenzene is also an organic compound. The beginning of this process is due to the diligent study of the field of organic synthesis. In the past, organic synthesis was just emerging, and everyone was dedicated to exploring the preparation of novel compounds.
At that time, chemists began to engage in the synthesis of fluorohalogenated aromatics with their outstanding wisdom and unremitting practice. After years of trials, or improving existing methods, or creating novel ways, the preparation of 3,4-difluorobromobenzene has gradually improved.
Early attempts, despite many obstacles, such as the harsh reaction conditions and low yield, chemists adhered to the determination and perseverance. With the evolution of chemical theory, the innovation of analytical methods, the synthesis process is becoming more and more perfect, the yield can be improved, and the purity is also high. 3,4-difluorobromobenzene has emerged in the fields of medicine, materials, etc., and has made great contributions to the advancement of science and technology and the prosperity of industry. Its development process is really a magnificent chapter in chemical exploration, which motivates post-study and continuous progress.
Product Overview
Description of 3,4-difluorobromobenzene
3,4-difluorobromobenzene is also an important agent in organic synthesis. Its color is clear and transparent, liquid, and has a special smell.
In the chemical industry, it has a wide range of uses. It is a key intermediate for the synthesis of many complex organic compounds. Difluorobromobenzene can be introduced through specific reactions to create products with unique properties. For example, in pharmaceutical research and development, it participates in the construction of specific drug molecular structures to help improve drug activity and targeting; in materials science, it involves the synthesis of special functional materials to enhance the stability and functionality of materials.
Preparation method, often using benzene as the starting material, through halogenation, fluorination and other series of reactions. However, the preparation process needs to control the reaction conditions, such as temperature, pressure, catalyst dosage, etc., to ensure the purity and yield of the product.
3,4-difluorobromobenzene has active chemical properties and should be properly stored and transported. Store in a cool, dry and ventilated place, avoid open flames and hot topics, and prevent mixed storage and transportation with oxidants and alkalis, so as not to cause danger.
Physical & Chemical Properties
Today, there is a thing called 3,4-Difluorobromobenzene. The physical and chemical properties of the thing are quite important to our generation.
In terms of physical properties, this thing has a specific color, state, and taste. At room temperature, it may be in a certain state, and its color is viewed, or it is a certain color. Smell it, and its taste is also characteristic. And its melting and boiling point has a fixed number, which is related to the state of its environment. Density is also a key physical property, affecting its floating and sinking in the medium.
On chemistry, the presence of fluorine and bromine atoms in its structure gives it unique reactivity. When encountering a certain type of reagent, it can react by substitution, and exchange groups with other substances due to its active atom. Or under certain conditions, additive changes are involved to add new parts to the molecular structure. This is due to the properties of chemical bonds in molecules and the distribution of electron clouds of atoms. It is of great significance to explore the rationalization of this substance in the chemical industry.
Technical Specifications & Labeling
3,4-Difluorobromobenzene is a key intermediate in organic synthesis. Its preparation process is very delicate and involves many factors.
To make this product, the selection and ratio of raw materials are extremely important. Based on suitable halogenated aromatics, with specific fluorine sources, mixed according to precise molar ratios, this is the basis for the beginning of the process.
During the reaction process, the temperature control and pressure adjustment need to be just right. In a closed reactor, the temperature is often maintained at a specific range, and the pressure is also stable at the corresponding value, in order to ensure the orderly progress of the reaction and improve the purity and yield of the product.
As for the identification of the product, in terms of appearance, it should be a colorless to light yellow liquid with its unique smell. After instrument analysis, its infrared spectrum, nuclear magnetic resonance and other data have characteristic peaks, which can be used for identification. Its purity standard also needs to reach a certain proportion, and the impurity content is strictly controlled, so as to meet the parameters of the product. It can be used for subsequent organic synthesis and play an important role in the field of fine chemicals.
Preparation Method
The method of making 3,4-difluorobromobenzene is related to the raw materials and production process, reaction steps and catalytic mechanism. First take suitable raw materials, such as compounds containing fluorine and bromine. The production process, the first control of the reaction conditions. The reaction steps must be carried out in sequence. First, the fluorine-containing reagent meets the bromine-containing substrate, and the reaction is promoted at a specific temperature and pressure. The catalytic mechanism is also crucial. Appropriate catalysts can be added to increase the reaction rate and improve the purity of the product. If a metal complex is used as a catalyst, it can effectively reduce the activation energy of the reaction and make it easier for the two to combine. In this way, after a series of operations, according to the standard process, a relatively pure 3,4-difluorobromobenzene can be obtained, and the production efficiency and stability can be guaranteed.
Chemical Reactions & Modifications
The chemical reaction and modification of 3,4-Difluorobromobenzene are studied today. The substance is also very important in the field of organic synthesis.
The method of the past, the preparation of this product, often encountered complicated steps, and the yield was not high. Looking at its chemical reaction, the method of nucleophilic substitution, although it can be achieved, but the side reactions are frequent, resulting in impure products.
In order to modify, scholars have been exhausted. Try new catalysts, hoping to increase the efficiency of the reaction and reduce the rate of side reactions. And adjust the reaction conditions, such as temperature, pressure and solvent, to get the method of optimization.
After all kinds of efforts, gradually obtained. Under the new catalyst, the reaction rate is increased, and the purity of the product is also improved significantly. This chemical reaction and modification research will pave the way for the industrial application of 3,4-Difluorobromobenzene, and there may be a wider range in the future.
Synonyms & Product Names
3,4-Difluorobromobenzene is also a chemical substance. In today's world, this substance has many synonymous names and commodity names. Its synonymous name depends on the analysis of chemical structure or the convention of naming in the past. The name of the product is chosen by merchants for its characteristics, uses, or for ease of identification.
However, regardless of its name, the essence of 3,4-difluorobromobenzene remains unchanged. It has unique chemical properties and is a key raw material in the field of organic synthesis. It can react with various reagents to obtain other compounds, which are used in medicine, pesticides and other industries.
Therefore, exploring its synonymous name and commodity name is meaningful in chemical research and industrial production. It can make people in the industry communicate seamlessly, and also help the promotion and application of products. Observing the change of its name, we can see that the development of the chemical field and the evolution of technology are reflected in the change of names.
Safety & Operational Standards
"Specifications for the safety and operation of 3,4-difluorobromobenzene"
The use of 3,4-difluorobromobenzene is also an important product in chemical research. Its characteristics are special, and it is related to the safety of the experiment and the standard of operation. Don't be careless.
The first word is safety. This thing is dangerous to a certain extent, and its gas or contact with the skin or entering the body can cause harm. Therefore, when it exists, it is advisable to keep it in a cool, dry and well-ventilated place, avoiding fire and hot topics, to prevent accidents. When taking it, you must wear protective equipment, such as gloves, eyepieces, and masks, to protect yourself. If you accidentally touch it, rinse it with water quickly, and if it is serious, seek medical attention.
Secondary discussion on operating specifications. At the beginning of the experiment, be familiar with the damage of the instrument and make sure there is no shortage. Measure 3,4-difluorobromobenzene, when accurate, and handle the measuring tool according to the regulations. When reacting, temperature control and pressure control must abide by the procedures, slowly add slow stirring, and do not make sudden changes. And the experimental environment should be clean and clean, and there should be no sundries, so as not to disturb the reaction sequence.
And its waste, can not be discarded. According to environmental protection regulations, classified disposal, anti-pollution environment. All experiments involving 3,4-difluorobromobenzene must be kept in mind, follow safety rules, and abide by the standard of operation, so as to ensure the smooth progress of the experiment, the safety of personnel, and the prevention of disasters.
In this way, with a rigorous heart and standard actions, we can make good use of 3,4-difluorobromobenzene, and add bricks and mortar to the industry of chemical research without any worries.
Application Area
Today there is a thing, called 3,4 - Difluorobromobenzene, which can be used in all kinds of fields. In the way of medicine, it can be used as the foundation of medicine, to help medicine make prescriptions, and to treat people's diseases. Because of its unique nature, it can combine with other things, adjust the effect of medicine, and increase the power of medicine.
In the world of materials, it can also develop its capabilities. It can be the source of new materials, endowing materials with characteristics, or increasing their strength, or changing their properties, so that the materials are suitable for all kinds of ingenious environments, such as exquisite equipment and high-tech utensils.
Furthermore, in the way of chemical research, it is an important thing. The research assistant explores the secrets of chemistry, the changes of bright things, opens a new path, seeks the unknown, and introduces a new chapter in the world of chemistry. Therefore, 3,4 - Difluorobromobenzene in many application fields such as medicine, materials, and chemical research, all of which have extraordinary value and are truly something that cannot be underestimated.
Research & Development
In recent years, Yu devoted himself to the research of 3, 4 - Difluorobromobenzene. This compound has great potential in the field of organic synthesis and is widely used.
At the beginning, I explored the method of its preparation, and after repeated experiments, many paths encountered obstacles. Or the raw materials are rare, or the reaction conditions are harsh, and the yield is quite low. However, I was not discouraged, and devoted myself to studying the classics and visiting the Fang family.
After obtaining a method, adjust the temperature, pressure and catalyst dosage of the reaction. In the initial test, the yield rose slightly, but it still did not meet expectations. Then repeated optimization, after months of work, the yield was finally significantly improved.
At present, although the preparation of 3, 4 - Difluorobromobenzene has been successful, its application and expansion are still far away. In the future, we should focus on the exploration of new materials, drug research and development and other fields, hoping to make more breakthroughs, and contribute to the development of chemistry and the progress of industry.
Toxicity Research
To study the toxicity of 3,4 - Difluorobromobenzene this substance. The study of toxicity is related to the safety of living beings and cannot be ignored.
At first, the chemical structure of fluorine and bromine atoms attached to the benzene ring may lead to unique properties. In the experiment, various small animals were tested. If you give an appropriate amount of 3,4 - Difluorobromobenzene, you can see that it has an uneasy state and acts a little disorderly.
And analyze the way it enters the body, either by breathing or through the skin. After entering the body, it is suspected that the biochemical process of the body is disturbed, and the energy of the cell may be hindered by it.
However, if you want to clarify the details, you need to search for data and do more experiments to determine its toxicity and harm. When the world uses this substance, it can avoid its harm, take advantage of its benefits, and ensure the safety of all living beings.
Future Prospects
I have tried to study chemical things, and now look at 3,4 - Difluorobromobenzene this product, the mind has some thoughts, and it is related to its future development.
This material is unique, or it will shine in the field of medicine. In the future, it may be the cornerstone of creating new medicines, helping physicians to conquer diseases and save them from pain. In the field of materials, it is also expected to become the key to innovation, making materials unique and used in all kinds of exquisite tools.
Although the road ahead is uncertain, I firmly believe that with time, everyone will be able to study together and explore its potential. 3,4 - The future of Difluorobromobenzene is like the early rise of Chenxu, full of hope, and will definitely bring endless well-being to the world and open up a new realm.
Where to Buy 3,4-Difluorobromobenzene in China?
As a trusted 3,4-Difluorobromobenzene manufacturer, we deliver: Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements. Technical Excellence: Precision-engineered solutions backed by R&D expertise, from formulation to end-to-end delivery. Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.
Frequently Asked Questions

As a leading 3,4-Difluorobromobenzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

What are the main uses of 3,4-difluorobromobenzene?
3,2,4-Diethylaniline is an organic compound, and its main uses are as follows:
First, in the dye industry, it is a key intermediate. Through a series of chemical reactions, it can be converted into many dyes with bright colors and excellent properties. For example, in the synthesis of some azo dyes, 3,2,4-diethylaniline can be used as a diazo component or a coupling component to participate in the reaction, thus giving the dye its unique color and stability. It is widely used in the textile printing and dyeing industry to make the fabric appear colorful.
Second, in the field of medicine, it also plays an important role. It is an indispensable raw material for the synthesis of specific drugs. With its special chemical structure, it can participate in the construction of drug molecules, laying the foundation for the development of drugs with specific curative effects. Like some drugs with antibacterial and anti-inflammatory effects, in their synthesis path, 3,2,4-diethylaniline may be used as a starting material or an important reaction intermediate, and finally an effective pharmaceutical ingredient can be obtained through multi-step reactions.
Third, in the field of organic synthesis, it is an extremely useful reagent. Because it contains amino and ethyl functional groups, it can participate in various organic reactions, such as nucleophilic substitution reactions, acylation reactions, etc. Through these reactions, more complex organic molecular structures can be constructed, providing an important material basis for the research and development of organic synthetic chemistry, helping scientists synthesize organic compounds with novel structures and properties, and expanding the boundaries of organic chemistry.
What are the physical properties of 3,4-difluorobromobenzene?
3,4-Diethoxybenzaldehyde is a genus of organic compounds. It has special physical properties, so let me describe it to you in detail.
First of all, its appearance, under room temperature and pressure, 3,4-diethoxybenzaldehyde is colorless to light yellow liquid, with a clear texture and a certain fluidity. Its color is light yellow, just like the chrysanthemum that blooms in autumn, shimmering and shining, with a unique charm.
Second time on its smell, this thing emits a fragrant fragrance, with a unique and rich aroma. It is like the clear fragrance in the mountains and forests and the rich smell in the market. It is fragrant but not greasy. The smell is refreshing and refreshing, just like smelling a wisp of fragrance in a quiet place, refreshing.
Furthermore, its melting point and boiling point. The melting point is about -10 ° C. Under this temperature, the substance gradually converts from liquid to solid state. If it is water in winter, it will condense in case of cold. The boiling point is about 285-287 ° C. When the temperature rises to Si, the substance will transform from liquid to gaseous state, such as cloud evaporation, and become invisible.
Repeat on its solubility. 3,4-diethoxybenzaldehyde is slightly soluble in water, because its molecular structure is dominated by hydrophobic groups, and the polarity of water is inconsistent with it. Just like oil and water, it is difficult to melt. However, it is soluble in organic solvents such as ethanol and ether, and can be evenly dispersed in it, just like fish swimming in water, free and smooth. This property also makes it promising in organic synthesis and other fields.
In addition, its density is about 1.042 - 1.046 g/cm ³, which is slightly heavier than water. It is placed in water, such as a stone sinking abyss, and slowly sinks.
In summary, 3,4-diethoxy benzaldehyde, with its unique physical properties, has shown important value in many fields such as chemicals and fragrances, and is a key material for many industrial production and scientific research.
What are the chemical properties of 3,4-difluorobromobenzene?
3% 2C4-diethylbenzoic acid is an organic compound with unique chemical properties. It is a white to light yellow crystalline powder and is quite stable at room temperature and pressure.
This compound is acidic because it contains a carboxyl (-COOH) functional group. Hydrogen atoms in the carboxyl group are easier to dissociate, causing it to exhibit acidic properties. Under suitable conditions, it can react with bases to form corresponding carboxylic salts and water. For example, when reacted with sodium hydroxide (NaOH), 3% 2C4-diethylbenzoic acid and water will be formed.
The carboxyl group of 3% 2C4-diethylbenzoic acid can also participate in the esterification reaction. When co-heated with alcohols under acid catalysis, the hydroxyl group (-OH) in the carboxyl group will combine with the hydrogen atom in the alcohol to form water, and at the same time form an ester compound. This reaction is often used in organic synthesis to prepare specific esters, which are widely used in the fields of fragrances, drugs and so on.
Because of the benzene ring structure contained in the molecule, 3% 2C4-diethylbenzoic acid has aromatic properties. The benzene ring endows the compound with certain stability and special electron cloud distribution. In chemical reactions, the benzene ring can undergo electrophilic substitution reactions, such as halogenation, nitration, sulfonation, etc. For example, under iron catalysis, it can react with bromine, and bromine atoms replace hydrogen atoms on the benzene ring.
In addition, the alkyl (diethyl) part of the 3% 2C4-diethylbenzoic acid molecule brings a certain fat solubility to it. This makes it more soluble in organic solvents such as ethanol and ether, but relatively less soluble in water. This solubility characteristic affects its behavior in different reaction systems and practical applications.
What are the preparation methods of 3,4-difluorobromobenzene?
To prepare 3% 2C4-diethoxybenzene, the following methods are used:
First, resorcinol is used as the starting point, and diethyl sulfate is reacted with diethyl sulfate in an alkaline environment. First dissolve resorcinol into sodium hydroxide solution, control the temperature to a suitable level, slowly drop in diethyl sulfate, and stir continuously. After the reaction is completed, adjust the pH to neutral with acid, and purify by extraction, distillation, etc., to obtain 3% 2C4-diethoxybenzene. This is a classic method. The raw materials are easy to obtain, but the reaction steps are slightly complicated, and the conditions need to be strictly controlled, otherwise the yield will not be good.
Second, take catechol as the source and react with bromoethane in potassium carbonate and phase transfer catalyst. In the reactor, add catechol, potassium carbonate, phase transfer catalyst and an appropriate amount of solvent, such as acetonitrile, etc., to a certain temperature, and drop bromoethane. After the reaction, the salt is filtered, the solvent is evaporated, and then refined by column chromatography. This method is relatively simple to operate, and the reaction conditions are mild. However, bromoethane is toxic and volatile, and safety protection must be paid attention to during operation.
Third, with 3-ethoxy-4-hydroxybenzaldehyde as the substrate, 3-ethoxy-4-hydroxybenzyl alcohol is first reduced, and then treated with halogenated reagents, such as thionyl chloride, to obtain 3-ethoxy-4-chlorobenzyl, and finally reacted with sodium ethanol. Although there are many steps in this way, the selectivity of each step is good, which is conducive to the production of high-purity products, but the cost of raw material 3-ethoxy-4-hydroxybenzaldehyde is slightly higher, which affects the large-scale preparation.
All methods for preparing 3% 2C4-diethoxybenzene have advantages and disadvantages. In actual preparation, it is selected according to factors such as raw material availability, cost, and product purity.
What should be paid attention to when storing and transporting 3,4-difluorobromobenzene?
3,4-Diethylhexane is also an organic compound. During storage and transportation, many matters must be paid attention to.
The first priority is safety. This compound is flammable, so the storage place must be kept away from fire and heat sources, and fireworks are strictly prohibited. The warehouse should also be well ventilated to prevent the accumulation of combustible gases and the risk of explosion. When transporting, the vehicles and containers used must have fire protection and anti-static facilities, and the escort personnel should also be familiar with emergency response methods.
The second is to prevent leakage. The storage container must be tightly sealed to prevent the material from evaporating and leaking. During transportation, it is also necessary to ensure that the container is not damaged and the connection part is firm. In the unfortunate event of a leak, unrelated personnel should be evacuated quickly, warning signs should be set up around the site, and emergency measures should be taken, such as absorbing the leak with inert materials such as sand and vermiculite, and not allowing it to flow into sewers, rivers, etc., so as not to pollute the environment.
Furthermore, temperature and humidity should not be ignored. The temperature of the storage environment should be maintained within an appropriate range to avoid too high or too low. If the temperature is too high, it may cause the material to evaporate and increase the internal pressure of the container; if the temperature is too low, it may cause the material to solidify, which will affect the access. Humidity should also be controlled. If the humidity is too high, it may rust and corrode the container, which will damage the sealing performance.
Storage containers and transportation vehicles should be marked with the name of the compound, dangerous characteristics and other information, so that relevant personnel can see at a glance, and appropriate protection and disposal measures can be taken according to the label during operation.
In addition, storage and transportation equipment and tools should be regularly inspected and maintained. Ensure that containers, pipelines, valves, etc. are not damaged or leaked; the braking, steering and other safety systems of transportation vehicles should also be kept in good condition to ensure the safety of storage and transportation.