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3,4-Difluorobenzenethiol

3,4-Difluorobenzenethiol

Hongda Chemical

Specifications

HS Code

201183

Chemical Formula C6H4F2S
Molecular Weight 146.16
Appearance Typically a colorless to light - yellow liquid
Boiling Point Approximately 180 - 182°C
Density Around 1.31 - 1.33 g/cm³
Solubility In Water Insoluble in water
Solubility In Organic Solvents Soluble in common organic solvents like ethanol, acetone, and dichloromethane
Odor Characteristic, strong, sulfur - containing odor
Flash Point Relatively low, a potential fire hazard

As an accredited 3,4-Difluorobenzenethiol factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

Packing & Storage
Packing 100g of 3,4 - difluorobenzenethiol packaged in a sealed, corrosion - resistant bottle.
Storage 3,4 - difluorobenzenethiol should be stored in a cool, dry, well - ventilated area, away from heat sources and open flames. Keep it in a tightly sealed container to prevent vapors from escaping. Store it separately from oxidizing agents and incompatible substances to avoid potential reactions. Use appropriate secondary containment to catch any spills.
Shipping 3,4 - difluorobenzenethiol is shipped in specialized, corrosion - resistant containers. It's carefully packed to prevent leakage during transit, following strict chemical shipping regulations to ensure safety.
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3,4-Difluorobenzenethiol 3,4-Difluorobenzenethiol
General Information
Historical Development
3,4-Difluorothiophenol is also a chemical substance. The history and evolution of its substance can be described. The first time, the exploration of chemical substances, and this product. In the early days, there were many studies, because of the nature of the analyte and the method of making the substance, all need to be carefully researched.
The craftsman has been working for years and months, using different methods to find the solution. Or change the solution, or easy to use, hoping to find a good method to make 3,4-difluorothiophenol. In the process, there are setbacks, and there are small achievements. The month has changed, the technology has changed, and the method of making this substance is exquisite, and its quantity and degree are both sufficient. Therefore, 3,4-difluorothiophenol has been used in the field of chemical engineering, and has been used in many studies and workshops to promote the new process of chemical engineering.
Product Overview
3,4-Difluorothiophenol is an organic compound. It may be a colorless to light yellow liquid with a special mercaptan odor. This compound is widely used in the field of organic synthesis.
Its preparation method is often prepared from the corresponding halogenated aromatic hydrocarbons and sulfur-containing reagents through a specific reaction process. During the reaction, it is necessary to pay attention to the reaction conditions, such as temperature, catalyst dosage, etc., which are all related to the purity and yield of the product.
3,4-Difluorothiophenol has important applications in pharmaceutical chemistry, materials science, etc. In the field of medicine, it may be used as a key intermediate for the synthesis of specific drugs, assisting the development of new drugs. In materials science, or can participate in the preparation of materials with special properties, contributing to the improvement and innovation of materials.
Physical & Chemical Properties
3,4-Difluorobenzenethiol are organic compounds whose physical and chemical properties are particularly important. Looking at its physical properties, at room temperature, this substance is often in a liquid state and has a special odor. Its boiling point is in a specific range, which is related to its volatilization characteristics; the melting point is also fixed, characterizing its state transition temperature.
As for chemical properties, because it contains thiol groups, it has active chemical activity. It is easy to react with electrophilic reagents, such as with halogenated hydrocarbons. The sulfur atom of the thiol group attacks the carbon atom of the halogenated hydrocarbons with its lone pair of electrons, and the halogen ions leave to form new organic sulfur compounds. Under the action of oxidizing agents, the thiol group is oxidized, and the structure and properties are changed. These physical and chemical properties provide a key foundation and possible path for the preparation of special functional materials, pharmaceutical intermediates, etc. in the field of organic synthesis.
Technical Specifications & Labeling
3,4-Difluorothiophenol is an important product of the chemical industry. Its process specifications and identification (product parameters) are related to the quality of production.
Process specifications, starting from the selection of raw materials, must be carefully selected, impurities must be micro. The reaction conditions should be precisely controlled, and the temperature, pressure, and reaction time are all fixed. Such as the reaction temperature, or controlled in a specific range, to promote the smooth reaction and increase the yield. The pressure also needs to be adapted to make the reaction stable.
In terms of identification (product parameters), purity is the key, it should reach a high standard, and the impurity content must be strictly controlled. Appearance, odor and other characteristics are also clearly defined. These standards and logos are like the beacons of a boat, guiding products on the right track of quality, helping industrial production move forward in an orderly manner and ensuring their competitiveness in the market.
Preparation Method
To make 3,4 - Difluorobenzenethiol, we should prepare the raw materials first. Take the genus of fluorobenzene, combine it with other agents, and adjust it by a wonderful method. The process is as follows: First, mix fluorobenzene with a certain agent according to the square, put it into a special device, and control the temperature. When it is finished, analyze the product, purify it several times, remove impurities and store sperm.
The steps should be followed, and the regulations must be observed. The level of temperature and the length of time are all important. Control the temperature in moderation, do not make it too much or too little, and cause it to be biased. The duration should also be appropriate, the long time will be expensive, and the short time will not be fully met.
As for the mechanism of catalysis, it is based on a certain catalyst to induce it, promote the speed of response, and reduce the ability of response. The amount of catalyst is also fixed, and the amount is not suitable. Make good use of this system, it can become a good product for all uses.
Chemical Reactions & Modifications
The chemical change and modification of 3,4-Difluorobenzenethiol. The chemical reaction of this substance is related to the chemical industry and plays an important role in the synthesis.
At the beginning, the reaction path was mostly based on the ancient method, although it was effective, the drawbacks were also obvious. The yield was not ideal, and the by-products were complicated, and the separation was time-consuming and laborious.
After careful study, the method of change gradually emerged. With the introduction of new catalysts, the reaction conditions were fine-tuned, and the effect was miraculous. The yield was greatly increased, and the by-products were sharply reduced.
The modification was aimed at optimizing the performance. After modifying the structure, the stability and solubility of this substance were improved. This revolutionary move, in the field of chemistry, such as the stone hitting the water, the ripples scattered, paving a new way for follow-up research, and hoping to lead the way for colleagues to explore the mystery of chemistry together.
Synonyms & Product Names
3,4-Difluorothiophenol is also the name of the chemical compound. Its name is not the same, or the same name. The same name, so it shows its characteristics and special characteristics, making it easy to use.
This substance is an important raw material in the field of chemical research. Its use is not enough, and it can be used in general chemical products. Or it is the opposite of the synthesis, and it is the molecule of the original.
Its trade names are also different, depending on the home and use. However, what is the name, its original nature is not good. For a chemist, being familiar with its same name and trade name is the basis of research. Knowing its name can only be used to obtain materials and promote the research process to explore the secrets of the world.
Safety & Operational Standards
"Safety and Operation Specifications for 3,4-Difluorothiophenol"
3,4-Difluorothiophenol is an important substance in chemical research. In terms of experimental operation and storage, safety and operation specifications must be strictly followed to ensure the well-being of personnel and the smooth operation of the experiment.
First words storage. This substance should be stored in a cool and ventilated warehouse. Keep away from fire and heat sources, and the storage temperature should not exceed 30 ° C. It should be stored separately from oxidants, acids, and bases, and should not be mixed. The storage area should be equipped with suitable materials to contain leaks.
The operation is described again. Operators must be specially trained and strictly abide by the operating procedures. It is recommended that operators wear self-priming filter gas masks (half masks), chemical safety glasses, anti-poison penetration work clothes, and rubber oil-resistant gloves. Keep away from fires and heat sources. Smoking is strictly prohibited in the workplace. Use explosion-proof ventilation systems and equipment. Prevent steam leakage into the air of the workplace. Avoid contact with oxidants, acids, and alkalis. When handling, pack and unload lightly to prevent damage to packaging and containers. Equip with the appropriate variety and quantity of fire-fighting equipment and leakage emergency treatment equipment. Harmful substances may remain in the empty container.
If a leak occurs accidentally, in the event of a small leak, it can be mixed with sand, dry lime or soda ash and collected in a dry, clean, covered container. In the event of a large number of leaks, build a dike or dig a pit to contain it, cover it with foam, and reduce vapor hazards. Transfer it to a tanker or special collector with an explosion-proof pump, and recycle it or transport it to a waste disposal site for disposal.
In short, in all kinds of activities involving 3,4-difluorothiophenol, safety should be given top priority, and strict operating practices should be followed, so as to ensure that everything goes smoothly and avoid accidents.
Application Area
3,4-Difluorothiophenol is a special chemical substance. Its application field is quite wide, in the field of medicinal chemistry, it is the key raw material for the preparation of special drugs. It can help chemists make drugs for specific diseases, act precisely on lesions, and improve curative effect.
In the field of materials science, it also plays an important role. Through special reactions, it can be combined with other substances to create new materials with excellent performance, such as those with high stability and unique optical properties, for high-end electronic devices.
In addition, in organic synthetic chemistry, it is a powerful tool for building complex organic molecules. Chemists have skillfully designed reaction pathways to synthesize organic compounds with novel structures and unique functions, promoting cutting-edge research in organic chemistry. This highlights the key applications and potential of 3,4-difluorothiophenol in many fields.
Research & Development
In recent years, I have focused on the research of 3, 4 - Difluorobenzenethiol. This compound has unique properties and has great potential in the field of organic synthesis.
At the beginning, the preparation method was difficult and the yield was not as satisfactory. However, I and my colleagues worked tirelessly, checked the classics, and tried various paths. After months of hard work, we improved the synthesis process, optimized the reaction conditions, and studied the temperature, pressure, and reagent ratio carefully.
The effort paid off, the yield gradually increased, and the product purity was also good. This achievement is not only the joy of our generation, but also paves the way for its wide application. In the future, it is hoped to expand its application in the fields of medicine, materials, etc., promote the development of the industry, and contribute to the academic and industrial circles, in order to achieve greater success.
Toxicity Research
The study of toxic substances is related to people's health and health, and must be observed. Today there are 3,4 - Difluorobenzenethiol of this substance, and the study of its toxicity is quite important.
To observe this substance, in the field of chemistry, its properties are unique. To understand its toxicity, we should first examine its structure and explore its response to other things. Its molecular structure, or the cause of toxicity. Also observe its interaction with biological systems in different environments. In vitro experiments, observe its shadow on cells, or damage to cell structure, or disorderly metabolism. Re-enter the body to observe whether animal signs cause physiological violations and abnormal behavior.
The study of toxicity cannot be done overnight. It is necessary to apply multiple methods and investigate carefully in order to obtain the true meaning, so as to avoid its harm and ensure the peace of all beings.
Future Prospects
Today there is a thing called 3, 4 - Difluorobenzenethiol. I look at this thing, which is unique in nature and has unlimited potential. Although its use today may be limited, it has great expectations for future development.
This physicality can be the key to various reactions, in the field of organic synthesis, or can open up new paths. With its unique structure, it may be possible to produce unprecedented compounds, in pharmaceutical research and development, or can lead to miraculous drugs; in materials science, or can create excellent materials.
Our chemical researchers should study diligently and explore its mysteries with scientific methods. With time, it will be able to tap its maximum value, make 3,4-Difluorobenzenethiol shine in the future, for the well-being of the world, and for the progress of science.
Where to Buy 3,4-Difluorobenzenethiol in China?
As a trusted 3,4-Difluorobenzenethiol manufacturer, we deliver: Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements. Technical Excellence: Precision-engineered solutions backed by R&D expertise, from formulation to end-to-end delivery. Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.
Frequently Asked Questions

As a leading 3,4-Difluorobenzenethiol supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

What are the main uses of 3,4-difluorothiophenol?
3,2,4-Diethylbenzoic anhydride is an important raw material in organic synthesis. It has a wide range of uses and can be used as a key intermediate in the field of pharmaceutical synthesis to help create a variety of drugs. For example, when synthesizing compounds with specific pharmacological activities, the structural properties of 3,2,4-diethylbenzoic anhydride can enable the reaction to follow the established direction and build the key skeleton of drug molecules, laying the foundation for subsequent drug research and development.
In the field of materials science, it also plays an important role. It can participate in the synthesis process of polymer materials, giving materials unique properties by polymerizing with other monomers. For example, improving the heat resistance and mechanical properties of materials. Due to the ethyl and benzene ring structures in its molecular structure, it can affect the arrangement and interaction of polymer chains, thereby optimizing the overall properties of the material.
Furthermore, in the fragrance industry, 3,2,4-diethylbenzoic anhydride also has a place. Because it can be used as a raw material for fragrance synthesis, through a series of chemical reactions, compounds with unique aromas can be generated. These fragrances can be applied to perfumes, cosmetics and other products to add unique flavor and enhance product quality and market competitiveness.
In addition, in the field of fine chemicals, this compound is often used in the synthesis of various fine chemicals. With its special chemical structure, it can participate in complex organic reactions to generate fine chemicals with unique structures and excellent properties, meeting the needs of different industries for special chemicals. Overall, 3,2,4-diethylbenzoic anhydride has important uses in many fields and plays an indispensable role in promoting the development of related industries.
What are the physical properties of 3,4-difluorothiophenol?
3,4-Diethylbenzoic anhydride is an organic compound. Its physical properties are quite important, and I will describe them in detail for you today.
Looking at its appearance, at room temperature, 3,4-diethylbenzoic anhydride is mostly colorless to light yellow liquid, with uniform texture and fluidity, just like a clear spring, which can be seen from people. This appearance feature makes it easy to mix evenly with other substances in many reaction systems, laying a good foundation for subsequent reactions.
When it comes to odor, this substance emits a special aromatic smell. Although it is not as fragrant and sweet as flowers, it has a unique fragrance of a chemical substance, giving people a unique sense of smell.
Furthermore, its boiling point is one of the important physical constants. According to scientific determination, the boiling point of 3,4-diethylbenzoic anhydride is within a certain range. This boiling point characteristic determines its behavior during operations such as heating or distillation. When the temperature of the system gradually rises to near the boiling point, the substance will change from liquid to gaseous state, achieving the purpose of separation and purification of the substance.
In terms of melting point, under specific conditions, 3,4-diethylbenzoic anhydride will appear in a solid state. The exact value of its melting point is of great significance for maintaining the stability of the material's morphology during storage and transportation. If the external temperature is lower than the melting point, the substance will exist in a solid state for easy storage and transportation; conversely, if it is higher than the melting point, it will be in a liquid state.
Solubility is also a key property. 3,4-Diethylbenzoic anhydride is soluble in common organic solvents, such as ethanol, ether, etc. In organic solvents, it can be uniformly dispersed in molecular state, thus providing a homogeneous reaction environment for the reactants in the organic synthesis reaction, which greatly promotes the reaction progress, improves the reaction efficiency and product purity.
In addition, density is another physical property of the substance. Its density value reflects the mass of the substance per unit volume. This property plays an indispensable role in practical applications, such as solution preparation, measurement, etc., which helps to precisely control the amount of reaction materials and ensure the accuracy and stability of the experiment or production process.
Is the chemical properties of 3,4-difluorothiophenol stable?
The chemical properties of 3,2,4-diethylbenzoic anhydride are quite stable.
In this compound, the structure of diethyl gives it a certain steric hindrance, which changes its chemical activity. The conjugate system of benzene ring makes it aromatic, while the structure of benzoic anhydride gives it the general characteristics of acid anhydride. For acid anhydride, it can react with water, alcohol, amine, etc. However, 3,2,4-diethylbenzoic anhydride can increase the steric hindrance due to its substitution of diethyl group, and the reaction activity is slightly reduced than that of benzoic anhydride itself.
Under normal temperature and pressure, 3,2,4-diethylbenzoic anhydride can maintain a relatively stable state in the air, and it is not easy to spontaneously undergo significant chemical changes. It also has a certain tolerance to heat, and under moderate heating conditions, it is not easy to decompose.
In the field of organic synthesis, it is often used as an intermediate for specific reactions because of its stability. Because of its stability, it can exist under many reaction conditions without easy deterioration, providing a stable starting material for subsequent reactions.
In terms of storage, because of its stable nature, it can be stored for a long time without changing quality under conventional storage conditions, in a cool, dry and well-ventilated place. Although its properties are stable, it is still necessary to follow the safety procedures of general chemical substances when operating, avoid contact with strong oxidizing agents, strong reducing agents, etc., to prevent accidental chemical reactions.
What are the preparation methods of 3,4-difluorothiophenol?
The preparation method of 3,4-diethylbenzoic anhydride is mostly obtained by co-heating of acid chloride and carboxylate.
First prepare acid chloride, take an appropriate amount of 3,4-diethylbenzoic acid, place it in a clean reactor, add an appropriate amount of sulfoxide chloride, and use pyridine as a catalyst to heat and stir. Sulfoxide chloride reacts with benzoic acid to form 3,4-diethylbenzoyl chloride, and at the same time escapes sulfur dioxide and hydrogen chloride gas. After the reaction is completed, distillation and purification are completed to obtain pure 3,4-diethylbenzoyl chloride.
Reproduce carboxylate, take an appropriate amount of 3,4-diethylbenzoic acid, dissolve it in an appropriate amount of alkaline solution, such as sodium carbonate or sodium hydroxide solution, stir the reaction, make benzoic acid into carboxylate, after evaporation and crystallization, 3,4-diethylbenzoate can be obtained.
Then 3,4-diethylbenzoyl chloride and 3,4-diethylbenzoate are co-placed in the reaction vessel, heated and stirred. The two undergo nucleophilic substitution reaction, and then obtain 3,4-diethylbenzoic anhydride through intramolecular dehydration. After the reaction, the product is purified by extraction, washing, distillation and other steps.
It is also prepared by acid anhydride exchange method. Take 3,4-diethylbenzoic acid and acetic anhydride in a reaction kettle, add an appropriate amount of catalyst, such as sulfuric acid or p-toluenesulfonic acid, heat and stir. The acid anhydride exchange reaction between benzoic acid and acetic anhydride occurs to generate 3,4-diethylbenzoic anhydride and acetic acid. After the reaction, the acetic acid and unreacted acetic anhydride are removed by distillation, and then purified by recrystallization and other steps, and pure 3,4-diethylbenzoic anhydride can also be obtained.
What are the precautions for the storage and transportation of 3,4-difluorothiophenol?
3,4-Diethylbenzoic anhydride is an organic compound. The following things should be paid attention to during storage and transportation:
First, when storing, find a cool, dry and well-ventilated place. Because it is quite sensitive to heat, if placed in a high temperature environment, it may decompose or cause other chemical reactions, so the temperature should be maintained at a low level, usually no more than 30 ° C. And it is necessary to keep away from fires and heat sources to prevent open flames, static electricity and other factors that may cause fires.
Second, the substance should be stored separately from oxidants, acids, bases, etc., and must not be mixed. Due to its active chemical properties, contact with these substances is prone to violent reactions, and even the risk of explosion. For example, if it encounters an oxidizing agent, it may trigger an oxidation reaction, resulting in a sudden rise in temperature and an increase in pressure.
Third, the storage container must be tightly sealed to prevent leakage. Corrosion-resistant materials, such as glass, specific plastics, etc., should be selected to avoid corrosion and leakage of the container. And regular inspection of the storage container is required to check for signs of damage and leakage.
Fourth, when transporting, ensure that the packaging is complete and the loading is secure. The transportation vehicle should be equipped with the corresponding variety and quantity of fire-fighting equipment and leakage emergency treatment equipment. During driving, it should be protected from exposure to the sun, rain, and high temperature. When road transportation, drive according to the specified route, and do not stop in residential areas and densely populated areas.
Fifth, during storage and transportation, operators should take protective measures and wear appropriate protective gloves, protective glasses and gas masks. In the event of an unexpected situation such as a leak, personnel from the leaked contaminated area should be quickly evacuated to a safe area, quarantined, and strictly restricted access. Emergency personnel should wear self-contained positive pressure breathing apparatus and protective clothing. Do not let leaks come into contact with combustible substances (such as wood, paper, oil, etc.), and cut off the source of leaks as much as possible to prevent them from flowing into restricted spaces such as sewers and drainage ditches. Small leaks can be mixed with sand, dry lime or soda ash, or they can be rinsed with a lot of water. After the washing water is diluted, it can be placed in the wastewater system. A large number of leaks require construction of embankments or digging pits to contain them, covering them with foam to reduce steam hazards, and then transferring them to tankers or special collectors for recycling or transportation to waste disposal sites.