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3,4-Difluorobenzenesulphonyl Chloride

3,4-Difluorobenzenesulphonyl Chloride

Hongda Chemical

    Specifications

    HS Code

    156018

    Chemical Formula C6H3ClF2O2S
    Molecular Weight 226.60
    Appearance Typically a colorless to pale yellow liquid
    Boiling Point Around 240 - 245 °C
    Density Approximately 1.6 - 1.7 g/cm³
    Solubility Reacts with water, soluble in many organic solvents like dichloromethane
    Purity Can be available in high purity grades, e.g., 98%+
    Flash Point Highly flammable, flash point data may vary
    Hazard Corrosive, can cause severe burns to skin and eyes, harmful if inhaled or ingested

    As an accredited 3,4-Difluorobenzenesulphonyl Chloride factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing 500g of 3,4 - difluorobenzenesulphonyl chloride in a sealed, corrosion - resistant container.
    Storage 3,4 - difluorobenzenesulphonyl chloride should be stored in a cool, dry, well - ventilated area, away from heat sources and open flames. It should be kept in a tightly - sealed container, preferably made of corrosion - resistant materials. Due to its reactivity, store it separately from incompatible substances like bases, oxidizing agents, and reducing agents to prevent hazardous reactions.
    Shipping 3,4 - difluorobenzenesulphonyl chloride is a chemical that requires careful shipping. It should be packaged in corrosion - resistant containers. Shipment must follow hazardous chemical regulations, ensuring proper labeling and secure transportation to prevent spills and ensure safety.
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    3,4-Difluorobenzenesulphonyl Chloride 3,4-Difluorobenzenesulphonyl Chloride
    General Information
    Historical Development
    3,4-Difluorobenzenesulfonyl chloride, the development of this compound has gone through years of changes. At the beginning, the exploration of chemistry was like a night in ignorance, and everyone explored the mysteries of matter. Later, as the technology gradually refined, researchers gained insight into its characteristics. In the past, the synthesis method was still simple, and the yield was also minimal. However, scholars worked tirelessly to improve the process, so that the yield gradually increased and the quality was better. From the initial crude attempt to the precise preparation of today, it all depends on the efforts of countless chemists. Its application has also gradually expanded, and it has emerged in the fields of medicine and materials. The evolution of this compound is like a shining star in the long river of history, witnessing the long journey of chemical development from bleak to shining.
    Product Overview
    3,4-Difluorobenzenesulfonyl chloride is an important material involved in chemical research. Its color is pure and pure, it is white crystalline, and has a pungent smell.
    This substance has outstanding functions in the field of organic synthesis. Often used as a sulfonylating agent, it can combine with a variety of organic compounds to form new compounds. Its reactivity is quite good, which can make the reaction efficient and accurate.
    When preparing, strict process regulations are required. Control the temperature, pressure and ratio of materials in the reaction to obtain high-purity products. And because of its corrosive nature, it is necessary to pay attention to protection during operation to avoid contact with human skin, eyes, etc.
    Caution should also be used when storing. It should be placed in a cool, dry and well-ventilated place, away from fire and heat sources to prevent deterioration or danger. This 3,4-difluorobenzenesulfonyl chloride is an indispensable material in chemical research and production.
    Physical & Chemical Properties
    3,4-Difluorobenzenesulfonyl chloride is also a chemical substance. Its physical properties are colorless to slightly yellow liquids at room temperature, with a pungent odor. The melting point also has its own characteristics, the melting point is about [specific value], and the boiling point is near [specific value]. Looking at its chemical properties, it is very active. Sulfonyl chloride bases are very easy to react with many nucleophiles. If they meet alcohols, they become sulfonates; when they meet amines, they form sulfonamides. And because of the fluorine atom, its chemical stability and reactivity are unique, which can be used to create novel organic compounds. It is very useful in the synthesis of medicines and pesticides. It can add special properties to many compounds. It is a substance that cannot be ignored in chemical research and industrial production.
    Technical Specifications & Labeling
    Today there is a thing called 3,4-difluorobenzenesulfonyl chloride. The technical procedures and identification (product parameters) for the production of this thing are very important.
    Its technical procedures need to follow the fine method. From the selection of various raw materials, the precise amount should be controlled, and the steps of harmony, or temperature or pressure, are fixed. There should be no slight difference in the heat and time, so that the reaction is stable and orderly, so that a pure product can be obtained.
    As for the identification (product parameters), it is related to the characteristics of this thing. Color, taste and state should be detailed. Its purity geometry is particularly critical, and it must meet the highest standard. Impurities must be minimal. In addition, parameters such as melting point and solubility should also be clearly marked to ensure that users can make good use of them. This is also essential for technical procedures and identification (product parameters).
    Preparation Method
    In this paper, I would like to describe the preparation method of 3,4-difluorobenzenesulfonyl chloride. The raw materials and production process first need to select suitable starting materials, such as fluorobenzene compounds and sulfonating reagents. In the reaction step, the fluorobenzene and sulfonating agent should be reacted under specific conditions first, or temperature and pressure should be controlled to ensure the smooth reaction. The catalytic mechanism is also the key. The selection of suitable catalysts can promote the efficient reaction and improve the yield of products. If a specific metal salt or organic base is used as a catalyst, the reaction rate and direction can be precisely regulated. Through the synergy of such raw materials, steps and catalytic mechanisms, 3,4-difluorobenzenesulfonyl chloride is expected to be efficiently prepared, laying the foundation for its industrial production.
    Chemical Reactions & Modifications
    Wenfu wants to study 3,4 - Difluorobenzenesulphonyl Chloride, which is related to chemical reaction and modification. The beauty of chemistry lies in the change of the product, changing its properties and leading to new uses.
    In 3,4 - Difluorobenzenesulphonyl Chloride, its reaction path may involve nucleophilic substitution, and the activity of chlorine atoms is quite good. It can react with many nucleophilic reagents, easily introduce new groups, and change its molecular structure. This change can also adjust its physical and chemical properties.
    And think about its modification, you can use the reaction to add functional groups and give it new energy. or increase its solubility, or change its stability, so that it needs to be suitable and diverse.
    However, the way of chemistry is fine and careful. Each step of the reaction requires detailed investigation of conditions, temperature control, speed regulation, and agent selection are all related to success or failure. Only by careful research can we understand the mystery of the 3,4-Difluorobenzenesulphonyl Chloride reaction and modification, which is the foundation of the world.
    Synonyms & Product Names
    Today there is a product called 3,4-difluorobenzenesulfonyl chloride. This product is widely used in the field of chemical industry. Its aliases are also numerous, all of which are synonymous names and are closely related to the trade name.
    This 3,4-difluorobenzenesulfonyl chloride is a key material in organic synthesis. In the way of pharmaceutical research and development, it can be the cornerstone of the creation of new drugs; in the way of materials science, it can help the birth of new materials. Its synonymous name is either derived from its chemical structure or based on its characteristics. Although it is different, it actually refers to the same substance as the trade name.
    In our study and research of chemistry, it is essential to understand its synonymous names and trade names. It can make me accurate and avoid confusion when I am equal to academic exchanges and experimental operations. Therefore, when you explore carefully and are familiar with your heart, you can travel unimpeded and make achievements in the world of chemistry.
    Safety & Operational Standards
    Specifications for the safety and operation of 3,4-difluorobenzenesulfonyl chloride
    For those with 3,4-difluorobenzenesulfonyl chloride, chemical products are also used. It is strong in nature, and it must be operated in accordance with regulations to ensure safety.
    Where this object is involved, the first protection should be given. Operators wear special clothes to prevent its rot; wear masks and gloves to protect their eyes and skin. When entering the operation room, first pass the fresh air to dissipate its filth and make the air clear.
    When storing, it should be placed in a cool and dry place to avoid fire and heat. Do not mix with alkalis and alcohols, for fear of drama. After use, the utensil must be cleaned, and the residue should be properly disposed of, and it should not be discarded at will.
    When operating, handle with care and do not splash out. If it accidentally gets on the body, flush it with water quickly and then treat it with medicine. If it enters the eye, wash it with water urgently, and seek medical attention without delay.
    Furthermore, the reaction temperature control should be cautious. According to its nature, set the temperature in an appropriate area to avoid its boiling or runaway. And stir well to make it uniform.
    The discharge of exhaust gas must be treated and released in compliance. Waste residue and waste liquid should also be handled according to the law to avoid polluting the environment.
    In short, in 3,4-difluorobenzenesulfonyl chloride, the operator must understand its properties and follow safety and operation regulations. In this way, the purpose of scientific research can be achieved without risk of accidents.
    Application Area
    3,4-Difluorobenzenesulfonyl chloride is an important chemical compound. Its application field is quite extensive. In the field of pharmaceutical synthesis, it is often a key intermediate. Based on this substance, it can make special drugs, treat various diseases, and benefit the medical system. In the field of pesticide creation, it also plays an important role. With its participation, it can become an efficient pesticide, protect agricultural products from pests, and protect crops. And in the field of material science, 3,4-difluorobenzenesulfonyl chloride also has wonderful uses. It can help develop novel materials with specific properties to meet diverse needs. From this point of view, it is indispensable in many fields, promoting the progress of science and technology and production, and is sincerely a chemical treasure.
    Research & Development
    Today there is a product named 3,4-difluorobenzenesulfonyl chloride. As a chemical researcher, I have devoted myself to studying this product for a long time. Its research and development have a lot of experience.
    3,4-difluorobenzenesulfonyl chloride has unique properties and has potential in many fields of chemical industry. When I first came into contact with this product, I felt that its reaction mechanism was complex, and repeated experiments were required to clarify its properties. Every time I prepare a reagent and observe the reaction, it is a way to explore its mysteries.
    After long-term research, I gradually realized that it can be used as a key intermediate in organic synthesis. The reactions it participates in can derive a variety of compounds, opening up new paths for materials science, drug research and development, etc.
    Looking forward to its development, if the preparation process can be optimized, the purity and yield can be improved, and it will definitely shine in the industry. I will make unremitting efforts to promote the research of this product to a higher level and contribute to the development of chemistry.
    Toxicity Research
    Today there is a thing, called 3,4 - Difluorobenzenesulphonyl Chloride, in our chemical research. The study of its toxicity is crucial.
    This thing has chemical activity, but the signs of toxicity cannot be ignored. We test its effect on various things according to scientific methods. Try it with all kinds of living beings to observe its physiological changes and behavioral differences.
    After repeated tests, we found that this thing is quite toxic. Or damage the organs of living beings and disrupt their physiological order. Although it may be useful in industry, its toxicity risk must not be prevented.
    We chemical researchers should deeply investigate the reasons for its toxicity and seek preventive measures, in order to use it favorably and avoid its harm. Make sure that this chemical is beneficial to the development of mankind and not harmful.
    Future Prospects
    Wuguanfu 3,4 - Difluorobenzenesulphonyl Chloride This product is unique and has a wide range of uses. In this world, although it has been useful, there is still a vast space for future development.
    It can be used in various organic synthesis and is an important substance in the chemical industry. In the future, it may be able to make major breakthroughs in the way of pharmaceutical creation and cure more diseases. Or in the process of material research and development, it will emerge and make more sophisticated materials, which will be applied to the field of high technology.
    Although the current preparation method still has refinement, researchers will continue to study it. It is expected that in the future, better processes will be found, costs will be reduced, and productivity will be increased. Make this product more ubiquitous, shining brightly at all ends of industry and people's livelihood, and its achievements are limitless. It is indeed a bright star for future development.
    Where to Buy 3,4-Difluorobenzenesulphonyl Chloride in China?
    As a trusted 3,4-Difluorobenzenesulphonyl Chloride manufacturer, we deliver: Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements. Technical Excellence: Precision-engineered solutions backed by R&D expertise, from formulation to end-to-end delivery. Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.
    Frequently Asked Questions

    As a leading 3,4-Difluorobenzenesulphonyl Chloride supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

    What are the main uses of 3,4-difluorobenzenesulfonyl chloride?
    3,4-Diethoxybenzaldehyde is a key raw material in organic synthesis, and is widely used in many fields such as medicine, fragrances, and dyes.
    In the field of medicine, it is an important intermediate for many drug synthesis. For example, in the preparation of some cardiovascular disease drugs, 3,4-diethoxybenzaldehyde can participate in key reaction steps, and through a series of chemical reactions, a molecular structure with specific pharmacological activity is constructed, which plays a decisive role in drug activity and curative effect.
    In the field of fragrances, it gives fragrances a special aroma by virtue of its unique chemical structure. It can be used to prepare a variety of fragrances, such as floral and oriental fragrances, etc., to add unique charm and layering to fragrances, and enhance the quality and attractiveness of fragrances.
    In terms of dyes, 3,4-diethoxybenzaldehyde can be used as the starting material for synthesizing specific dyes. By reacting with other compounds, dye molecules with specific colors and dyeing properties are formed, which are widely used in textile, printing and dyeing industries, making fabrics show rich colors.
    In short, 3,4-diethoxybenzaldehyde plays an indispensable role in many industrial fields due to its unique chemical properties and structure, and is of great significance to promoting the development of related industries.
    What are the physical properties of 3,4-difluorobenzenesulfonyl chloride?
    3,4-Diethylbenzothiazolium iodide is an organic compound with many unique physical properties and applications in many fields. The following will describe its physical properties in detail in the style of ancient proverbs.
    This substance is solid under normal conditions, and its appearance may have a specific color or a crystalline form. Its texture is solid and stable, which is a characterization of its physical appearance. Looking at its solubility, it is soluble in specific organic solvents. This property is caused by the interaction between its molecular structure and solvent molecules. In case of polar organic solvents, it may be well miscible due to the matching of intermolecular forces, just like fish-water.
    Furthermore, its melting point and boiling point are also important physical properties. The melting point is the critical temperature at which a substance changes from a solid state to a liquid state. The melting point of 3,4-diethylbenzothiazolium iodide is constant, and this temperature reflects the strength of its intermolecular forces. When the external temperature reaches this melting point, the thermal motion of the molecules intensifies enough to overcome the lattice energy, causing the solid structure to disintegrate and turn into a liquid state. Similarly, the boiling point is the critical temperature at which the liquid state changes to a gaseous state. This temperature depends on the relationship between the intermolecular forces and the vapor pressure.
    In addition, density is also one of its characteristics. Density, the mass per unit volume of a substance is also. The density of 3,4-diethylbenzothiazolium iodide is established, reflecting the tight arrangement of its molecules. If the molecules are closely arranged, the mass contained in the unit volume is high, and the density is also high; otherwise, it is low.
    And its optical properties cannot be ignored. Or it has specific light absorption characteristics. Under specific wavelengths of light, the electrons in the molecule transition to absorb specific energy. This characteristic makes it useful in optical materials and other fields. For example, in some optical detection methods, its light absorption characteristics can be used to identify and analyze.
    In summary, the physical properties of 3,4-diethylbenzothiazolium iodide, such as appearance, solubility, boiling point, density, and optical properties, are determined by its molecular structure, and each property is interrelated, which together constitute its unique physical properties and lay the foundation for its application in chemical, materials, and other fields.
    What are the chemical properties of 3,4-difluorobenzenesulfonyl chloride?
    3,4-Diethylbenzaldehyde oxime is an organic compound with unique chemical properties. Its appearance is often white to light yellow crystalline solid or powder, and it is relatively stable at room temperature and pressure.
    In terms of physical properties, it has a specific melting point and boiling point, the melting point is about [specific value], and the boiling point is about [specific value]. It is insoluble in water, but soluble in organic solvents such as ethanol, ether, and chloroform. This solubility makes it a solute or a reaction medium in organic synthesis reactions.
    From the perspective of chemical properties, because the molecule contains an aldehyde oxime functional group, it has significant reactivity. In the aldehyde oxime group, the electronegativity of the nitrogen atom and the oxygen atom is very different, making it a nucleophilic reaction check point. It can react with many electrophilic reagents, such as reacting with halogenated hydrocarbons to form N-substituted aldoxime derivatives, which is of great significance in the construction of complex organic molecular structures.
    Under acidic or alkaline conditions, 3,4-diethylbenzaldehyde oxime can undergo hydrolysis. In acidic hydrolysis, aldoxime is converted into aldose and hydroxylamine salts; in basic hydrolysis, aldose and hydroxylamine are generated. This hydrolysis property can be used as a protection and deprotection strategy in organic synthesis, that is, the aldehyde group is protected by the formation of aldoxime, and then hydrolyzed to release the aldehyde group under suitable conditions.
    In addition, its oxime group can participate in the Beckmann rearrangement reaction. Under the action of a specific catalyst, oxime undergoes intramolecular rearrangement to form amide compounds, providing an effective way for the synthesis of amides.
    Due to its active chemical properties, 3,4-diethylbenzaldehyde oxime is widely used in organic synthesis, medicinal chemistry and materials science, and is often used as a key intermediate for the synthesis of biologically active compounds or functional materials.
    What is the preparation method of 3,4-difluorobenzenesulfonyl chloride?
    3,4-Diethylbenzaldehyde oxime is an organic compound. The preparation method is as follows:
    Take 3,4-diethylbenzaldehyde as the initial raw material. This aldehyde compound is a key starting material in many organic synthesis reactions. After preparing, place it in an appropriate reaction vessel, such as a round-bottom flask.
    Take a hydroxylamine reagent at a time, such as hydroxylamine hydrochloride, and dissolve it in an appropriate amount of solvent (such as ethanol, water, etc.) with an alkaline substance (such as sodium acetate) in an appropriate ratio to prepare a reaction solution. In this step, the basic substance acts to adjust the pH of the reaction system and assist the conversion of hydroxylamine into a more active nucleophile.
    Then, under stirring, the prepared hydroxylamine reaction solution is slowly dropped into the reaction vessel containing 3,4-diethylbenzaldehyde. Stirring can make the reactants fully contact, making the reaction easier to proceed. This reaction is a nucleophilic addition-elimination process. The nitrogen atom in the hydroxylamine has a lone pair of electrons, and launches a nucleophilic attack on the partially positively charged carbon atom in the aldehyde group. The intermediate is first formed, and then the intermediate eliminates a molecule of water to generate 3,4-diethylbenzaldehyde oxime.
    During the reaction process, it can be monitored by means of thin layer chromatography (TLC). When the raw material point disappears or reaches the expected reaction level, the reaction is stopped. Then, the reaction mixture is post-treated. Generally, the liquid separation operation is carried out first. If the product is layered with the reaction solvent, the organic phase containing the product can be directly separated; if it is not layered, an appropriate extractant (such as dichloromethane, etc.) needs to be added for extraction to collect the organic phase.
    The organic phase often contains impurities, and it needs to be dried with a desiccant such as anhydrous sodium sulfate to remove the residual water. Subsequently, the solvent and low boiling point impurities are removed by reduced pressure distillation to obtain a crude product. The crude product can be further purified by column chromatography and other methods. Appropriate stationary phase and mobile phase are selected. According to the difference in the distribution coefficient of the product and impurities between the stationary phase and the mobile phase, the separation is achieved, and the final pure 3,4-diethyl
    What are the precautions for storing and transporting 3,4-difluorobenzenesulfonyl chloride?
    3% 2C4-diethylaniline hydrochloride, when storing and transporting, there are various things to pay attention to.
    Its properties have specific chemical properties, and when storing, the first environment. It should be placed in a cool, dry and well-ventilated place. If it is in a humid place, it is prone to moisture and deterioration, which will damage its quality. And because it may react to air components, it needs to be sealed and stored to avoid excessive contact with air to prevent oxidation and other reactions from changing its properties.
    When transporting, be sure to follow relevant regulations and standards. Because it may be dangerous goods, the packaging should be firm and compliant to prevent leakage. The loading and unloading process must be handled with caution, light loading and light unloading, so as not to subject the package to severe impact or vibration, so as to avoid package damage and leakage. The means of transportation should also be clean and dry, and there should be no adverse reactions with other chemical residues. Transportation personnel also need to be professionally trained, familiar with the characteristics of this substance and emergency disposal methods. In case of emergencies, such as leakage, they can be handled quickly and properly to minimize harm. In short, whether it is storing or transporting 3% 2C4-diethylaniline hydrochloride, it needs to be treated with caution and operated in accordance with regulations to ensure safety and quality.