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3,4-Difluoro-(Isothiocyanato)-Benzene

3,4-Difluoro-(Isothiocyanato)-Benzene

Hongda Chemical

    Specifications

    HS Code

    760183

    Chemical Formula C7H3F2NS
    Molecular Weight 171.17
    Appearance Typically a solid (description may vary based on purity and handling)
    Melting Point Data may vary, needs specific experimental determination
    Boiling Point Data may vary, needs specific experimental determination
    Solubility In Common Solvents Solubility characteristics depend on the solvent, may be soluble in some organic solvents like dichloromethane
    Density Data may vary, needs specific experimental determination
    Vapor Pressure Data may vary, needs specific experimental determination
    Flash Point Data may vary, needs specific experimental determination
    Stability Can react with nucleophiles due to the isothiocyanate group, may require proper storage conditions

    As an accredited 3,4-Difluoro-(Isothiocyanato)-Benzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing 100g of 3,4 - difluoro-(isothiocyanato) - benzene packaged in air - tight glass vials.
    Storage Store 3,4 - difluoro-(isothiocyanato) - benzene in a cool, dry, well - ventilated area away from heat sources and ignition sources. Keep it in a tightly sealed container, preferably made of corrosion - resistant materials. Due to its potential reactivity, store it separately from incompatible substances like strong acids, bases, and oxidizing agents to prevent hazardous reactions.
    Shipping 3,4 - difluoro - (isothiocyanato) - benzene is shipped in accordance with hazardous chemical regulations. It's packaged securely in suitable containers, labeled clearly, and transported by carriers experienced in handling such chemicals to ensure safety during transit.
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    3,4-Difluoro-(Isothiocyanato)-Benzene 3,4-Difluoro-(Isothiocyanato)-Benzene
    General Information
    Historical Development
    The origin of 3,4-difluoro (isothiocyanate) benzene was unknown at the beginning, but it was only felt that the chemical substances were changeable. On the way to exploration, there were gradually clues.
    In the past, all the sages studied the mystery of chemistry, studying day and night, and using all kinds of tricks to analyze the properties of substances and explore the rules of reaction. Occasionally, new substances were obtained, and after repeated examination, they began to know the characteristics of 3,4-difluoro (isothiocyanate) benzene.
    At first, it was only a wonder in the laboratory, and then after in-depth research, they found it in various fields of industry and medicine, or it was of great use. Everyone then united their hearts and used the art of improvement to seek the method of mass production. Over the years, technology has gradually refined, and the use of this compound has also expanded day by day, adding a touch of color to the history of chemistry and opening up a new path for future research.
    Product Overview
    Today, there is a substance called 3,4-difluoro- (isothiocyanate) -benzene. This compound has a unique structure. In its molecule, fluorine atoms and isothiocyanate radicals are cleverly connected to the benzene ring.
    This substance has great potential in the chemical industry. Its unique structure gives it special chemical activity, or it can be used to prepare new materials or play a key intermediate in organic synthesis. With its activity, it can react with a variety of compounds to derive products with novel structures.
    In the process of research and development, scientists have deeply studied its properties. Strive to clarify its reaction law, explore the optimal synthesis path, and improve yield and purity. It is hoped that through the research on 3,4-difluoro- (isothiocyanate) -benzene, a new field of chemical innovation and application will be opened up, which will contribute to the development of chemical industry.
    Physical & Chemical Properties
    The physical and chemical properties of 3,4-difluoro- (isothiocyanate) -benzene can be studied. Looking at its shape, under normal conditions, it may be a colorless to slightly yellow liquid, clear and with a special smell, and its smell can be known. Its melting point is also one of its characteristics. The melting point is about [specific value], and the boiling point is at [specific value], which is related to the change of its phase state.
    Furthermore, solubility is an important property. In organic solvents such as ethanol and ether, it is quite soluble, which has a suitable interaction with organic solvent molecules due to the characteristics of molecular structure. In water, the solubility is relatively limited, which is caused by its hydrophobicity. The presence of isothiocyanate makes it easy to react with compounds containing active hydrogen, such as alcohols, amines, etc., which can be derived into many new compounds, which have great potential for application in the field of organic synthesis. All these physical and chemical properties are the cornerstones for in-depth investigation of this substance and the basis for its application in various fields.
    Technical Specifications & Labeling
    For 3-, 4-difluoro- (isothiocyanate) -benzene, the process specification and identification (product parameters) are the key. The process specification needs to be accurate, from the selection of raw materials, the selection of fine and pure materials, to the synthesis steps, when in accordance with strict regulations, the reaction temperature, duration, and material ratio must be carefully controlled, and a slight difference in the pool is a thousand miles away.
    On the label, the product parameters should be detailed and clear. Its appearance and properties need to be accurately described, such as pure impurities in color and solid-liquid in state. The proportion of ingredients contained must be without any ambiguity, and the purity geometry and impurity geometry should be clearly marked. In this way, the user can be aware of the application, operate properly, and ensure that the product plays its due role in various fields, living up to the difficulties of technological research, indicating the intention.
    Preparation Method
    There are currently methods for preparing 3,4-difluoro- (isothiocyanate) -benzene, which are described in detail as follows.
    Raw materials and production process: Fluorobenzene-containing compounds are used as starting materials, and halogen atoms are introduced through halogenation reaction. This is the key starting step. The halogenation reagent used needs to be precisely selected, depending on the reaction conditions and the characteristics of the target product.
    Reaction steps: First, fluorobenzene is added to a specific solvent, and under the action of a suitable temperature and catalyst, it is fully reacted with the halogenating agent to generate a halogenated fluorobenzene-containing intermediate. After that, the intermediate is substituted with thiocyanate to construct the isothiocyanate structure. This step requires fine regulation of reaction conditions, such as reaction temperature, time, and the proportion of reactants, to improve the purity and yield of the product.
    Activation mechanism: In order to make the reaction proceed efficiently, the raw material or intermediate is activated. By introducing activating groups, the activity of the reactants is enhanced, and the reaction is more likely to occur. At the same time, the reaction system is optimized, such as the selection of appropriate catalysts and auxiliaries, to reduce the activation energy of the reaction, improve the reaction rate and selectivity, so that 3,4-difluoro- (isothiocyanate) -benzene products can be obtained.
    Chemical Reactions & Modifications
    There is now a substance called 3,4-difluoro (isothiocyanate) benzene. In the field of chemistry, its reaction and modification are very important. The reaction of this compound, or involving nucleophilic substitution, the isothiocyanate group is quite active, and it is easy to interact with electron-rich groups, resulting in the formation of new bonds.
    As for modification, it can be changed by introducing specific functional groups. For example, adding a polar group may increase its solubility in polar solvents; adding a conjugate system may change its optical properties.
    Through various reactions and modifications, 3,4-difluoro (isothiocyanate) benzene can be used in various fields such as materials science and drug research and development, or it can show its unique effects and contribute to the progress of scientific research.
    Synonyms & Product Names
    "The same name and trade name of 3,4-difluoro- (isothiocyanate) -benzene"
    Today there is a product called 3,4-difluoro- (isothiocyanate) -benzene. In the field of chemistry, the same name or have various expressions. The composition of this substance is unique, fluorine and isothiocyanate are combined on the benzene ring.
    Chemical substances have many names of the same name, or vary depending on the focus of research, the order of discovery, and the region. The 3,4-difluoro- (isothiocyanate) -benzene, or other names, all refer to this specific compound.
    As for the product name, the merchant will promote it to the market, or take a name that is easy to identify and remember. Although the name is different, the quality of the reference remains unchanged. Chemical researchers need to specify the same name and product name in order to be accurate and not confused when researching and applying.
    Safety & Operational Standards
    3,4-Difluoro (isothiocyanate) benzene This chemical is very important for safety and operation standards. As chemical researchers, we must explain in detail.
    This chemical is dangerous. Its isothiocyanate root is highly chemically active. If it comes into contact with the skin or causes irritation, it will be redness, itching, and severe or blisters and ulceration. It is especially harmful to the eyes, or damage the vision, causing redness, swelling, severe pain, and even blindness. If it is inadvertently inhaled, it can irritate the respiratory tract, cause coughing, asthma, and even breathing difficulties, and damage lung function.
    When operating, strictly abide by the regulations. Work in a well-ventilated place and set up strong ventilation equipment to disperse volatile gas in time to prevent it from accumulating in space. Operators must wear protective equipment, such as protective clothing, which must be resistant to corrosion by this chemical and airtight; wear protective blindfolds, which are tough in texture and can effectively block chemical splashing; wear protective gloves to ensure complete protection of the hands.
    When taking it, the action should be slow and stable to prevent spills. If there is a spill, clean it up quickly according to a specific process. First cover it with materials with good adsorption, such as vermiculite and sand, then carefully collect it, put it in a special container, and dispose of it according to regulations.
    When storing, also use caution. It should be stored in a cool, dry and well-ventilated place, away from fire and heat sources. Separate from oxidizing agents, acids and other chemicals to prevent danger caused by mutual reaction.
    Only by strictly observing safety and operating standards can we ensure the safety of personnel and avoid accidents, so that the research and application of this chemical is smooth and secure.
    Application Area
    Today there is a thing named 3,4-difluoro- (isothiocyanate) -benzene, which has wonderful uses in various fields. In the path of medicine, it can help physicians make good medicines and treat various diseases in the world. With its unique properties, it can accurately act on the source of disease and help restore health.
    In the field of materials, it also exhibits extraordinary capabilities. It can participate in the preparation of novel materials to increase its toughness, corrosion resistance and other characteristics, adding new materials for engineering to meet the needs of all parties.
    In the realm of scientific research, it is a powerful tool for scholars to explore mysteries. With this material, it can expand the realm of cognition, open the door of the unknown, and promote the progress of science. The wide range of its applications and the depth of its influence are truly something that cannot be underestimated. It shines brightly in many fields and benefits the world.
    Research & Development
    Wutao is dedicated to the research of 3,4-difluoro (isothiocyanate) benzene. This substance has unique properties and has great potential in the field of organic synthesis.
    At the beginning, the method of its preparation was explored. After many attempts, the proportion of raw materials was prepared and the reaction conditions were regulated, all of which required fine work. In the control of reaction temperature and duration, a slight difference will affect the purity and yield of the product.
    Then, study its application prospects. Considering its chemical activity, it can react with a variety of compounds, and is expected to be used to create new drugs and functional materials.
    However, the road to research is not smooth, and it is faced with difficulties such as difficult removal of impurities and poor reaction selectivity. We study tirelessly, consult ancient books, and learn from the stones of other mountains, hoping to find a way to solve the problem, so as to promote the development of this material and make it better serve the world.
    Toxicity Research
    The study of the toxicity of this substance, Fu 3,4 - Difluoro- (Isothiocyanato) - Benzene, is a top priority today. Looking at the past, it is prudent to investigate the toxicity of various chemicals.
    Today's study of this 3,4 - Difluoro- (Isothiocyanato) - Benzene should be carefully observed for its physicochemical properties. It may show different toxicity characteristics under specific environments and conditions. And its contact routes, such as inhalation, skin contact, ingestion, etc., must be carefully investigated to understand the differences in toxicity caused by each route.
    Also consider its impact on the organism, from the cellular level to the overall function, all should be considered. It may cause cell damage, dysfunction, or even life-threatening. Therefore, the study of its toxicity should be based on scientific methods, rigorous and prudent, to clarify its harm, and provide evidence for protection, governance, etc., to ensure the well-being of all beings and the tranquility of the environment.
    Future Prospects
    Fu 3,4 - Difluoro - (Isothiocyanato) - Benzene This product has made a name for itself in today's chemical research. Looking at its characteristics, exquisite structure and specific performance, it has extraordinary potential.
    Looking to the future, it may have great potential in the field of materials science. With its unique chemistry, it is expected to develop new functional materials for use in electronic devices, which will greatly improve its performance, such as screen resolution and chip computing speed.
    In the biomedical industry, there is also infinite reverie. With its activity, it may be able to create special new drugs to accurately fight difficult diseases and bring good news to patients. And in the field of environmental protection, it may help to develop efficient purification materials and protect the peace of the world. In short, 3,4 - Difluoro - (Isothiocyanato) - Benzene has a bright future in the future, and it will be able to bloom in various fields and become a great cause.
    Where to Buy 3,4-Difluoro-(Isothiocyanato)-Benzene in China?
    As a trusted 3,4-Difluoro-(Isothiocyanato)-Benzene manufacturer, we deliver: Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements. Technical Excellence: Precision-engineered solutions backed by R&D expertise, from formulation to end-to-end delivery. Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.
    Frequently Asked Questions

    As a leading 3,4-Difluoro-(Isothiocyanato)-Benzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

    What is the main use of 3,4-difluoro- (isothiocyanate) -benzene?
    3,2,4-Diene- (isothiocyanate) -benzene has a wide range of uses. It has unique capabilities in the field of medicine. It can interact with various biomolecules in the body due to its unique structure. In the field of drug research and development, it can be used as a lead compound, modified by chemists, and is expected to become a special medicine, or to fight serious diseases, such as some difficult tumors. With its special activity, it can precisely target the source of the disease and curb the growth and spread of cancer cells.
    In the field of materials science, it also has extraordinary uses. It can participate in the synthesis of polymer materials, and through ingenious design, it can give materials new characteristics. If the material has specific optical properties, it can be used in optical display devices to make the image clearer and the color more gorgeous; or if the material has excellent adsorption properties, it can be used for environmental purification, adsorption of harmful gases and impurities, and to make the world fresh and clean.
    Furthermore, in the field of agriculture, it may also make contributions. Raw materials that can be used as special pesticides, after reasonable configuration, may be able to produce high-efficiency, low-toxicity and targeted pesticides, protect crops from pests and diseases, ensure abundant crops, help the prosperity of agriculture, and contribute to the foundation of people's lives. In short, this compound has infinite possibilities in many fields such as medicine, materials, agriculture, etc., and awaits further exploration by the world to benefit the world.
    What are the physical properties of 3,4-difluoro- (isothiocyanate) -benzene
    3% 2C4-diene- (isothiocyanate) -benzene, its physical properties are particularly important. This substance is either liquid or solid at room temperature, depending on its specific structure and surrounding environment.
    Look at its color, or colorless and transparent, or slightly yellowish, like the purity of morning dew, and like the shimmer of the early sun. Its smell, or pungent, is caused by the nature of isothiocyanate, and the smell is alarming, as if it were in a spicy environment.
    As for its density, it may be different from water. If it is larger than water, it will sink to the bottom of the water, like a pearl falling on the abyss; if it is smaller than water, it will float on the water, like a light boat floating on the blue waves. Its melting point and boiling point are also fixed. When the melting point is, solid and liquid change, just like ice and snow melting; when the boiling point is, the liquid and gas change, just like clouds rising.
    Solubility is also an important physical property. In organic solvents, it may be soluble, slightly soluble, or insoluble. Organic solvents such as ethanol and ether may be able to blend with them, just like water emulsion; while in water, it may have poor solubility, just like oil and water, difficult to mix.
    In addition, its volatility cannot be ignored. It may have a certain degree of volatility and gradually dissipate in the air, such as the curl of light smoke; the rate of volatilization may be slow or rapid, depending on temperature, air pressure and many other factors.
    These physical properties are of great significance in many fields such as chemical industry and medicine. Only by knowing its properties can it be used well, or it can be used as a raw material for synthesizing new substances, or as a good medicine for treating diseases and saving people. It has a wide range of uses and should not be underestimated.
    What are the chemical properties of 3,4-difluoro- (isothiocyanate) -benzene
    3% 2C4-diene- (isothiocyanate) -benzene organic compounds have complex chemical properties. In this compound, the presence of alkenyl groups and isothiocyanate gives it unique reactivity.
    alkenyl groups are unsaturated and can often participate in addition reactions. In terms of electrophilic addition, new carbon-halogen bonds or carbon-heteroatom bonds can be formed when encountering hydrogen chloride. In case of hydrogen chloride, the double bond of the alkenyl group can be opened, and chlorine and hydrogen atoms are added to the carbon atoms at both ends of the double bond to form halogenated hydrocarbon derivatives. This reaction is greatly affected by electronic effects and steric resistance, and different substituents will change the reaction rate and regioselectivity.
    In isothiocyanate, the triple bond between carbon and nitrogen is the active check point. It is nucleophilic and can react with electrophilic reagents. It can undergo nucleophilic substitution with compounds containing active hydrogen such as alcohols and amines. When reacting with alcohol, the sulfur atom in isothiocyanate attacks the hydroxyl carbon of the alcohol, and the hydroxyl group leaves to form thiocarbamates. Reacting with amines, thiourea derivatives are formed. This reaction is often used in organic synthesis to construct nitrogen-containing heterocyclic compounds or biologically active molecules.
    In addition, the conjugation system of the benzene ring in this compound also affects its chemical properties. The benzene ring can undergo electrophilic substitution reactions, such as halogenation, nitrification, sulfonation, etc. Due to the localization effect of alkenyl and isothiocyanate, the position selectivity of the substitution reaction is different from that of benzene itself. When alkenyl and isothiocyanate are electron-withdrawing groups, the electrophilic substitution reaction mostly occurs in the interposition of the benzene ring; if it is a power supply group, the ortho and para-position products are mostly.
    3% 2C4-diene- (isothiocyanate) -benzene is rich in chemical properties and has potential application value in organic synthesis, pharmaceutical chemistry and other fields. It can be diversified and converted through rational design of reaction conditions, providing an important intermediate for new functional materials and drug development.
    What is the production method of 3,4-difluoro- (isothiocyanate) -benzene?
    The preparation of 3,2,4-diene- (isothiocyanate) -benzene is an important task in the field of organic synthesis. The method is detailed as follows:
    First of all, suitable starting materials need to be prepared. Usually based on compounds containing benzene rings, such as benzene derivatives, which have functional groups that can be chemically converted to introduce dienes and isothiocyanate groups.
    As for the construction of diene structures, olefin metathesis reactions or related alkene-forming reactions are often used. If olefin metathesis is used, an alkenyl halide or an alkenol ether compound with a specific substituent should be selected and placed in a suitable reaction solvent together with a suitable metal carbene catalyst. Under a suitable temperature and inert gas protection atmosphere, the metal carbene catalyst promotes the rearrangement of the carbon-carbon double bond, and then forms the target conjugated diene structure.
    There are also multiple methods for the introduction of isothiocyanate groups. The amino-containing benzene derivative can first react with sulphosgene or carbon disulfide and an appropriate base. Taking carbon disulfide as an example, under the catalysis of alkali, the nucleophilic addition of amino groups and carbon disulfide occurs to form a dithiocarbamate intermediate, which is then reacted with halogenated hydrocarbons and converted into isothiocyanate groups through substitution, elimination, etc., to obtain the isothiocyanate complex structure.
    In the entire synthesis process, the conditions of each step of the reaction need to be precisely regulated. Temperature, reaction time, the proportion of reactants, and the solvent and catalyst used all have a profound impact on the yield and selectivity of the reaction. At the same time, in order to ensure the purity of the product, separation and purification methods such as column chromatography and recrystallization are often used in the reaction process to remove impurities such as unreacted raw materials, by-products and catalyst residues. In this way, 3,2,4-diene- (isothiocyanate) -benzene can be obtained efficiently and with high purity.
    What are the precautions for the use of 3,4-difluoro- (isothiocyanate) -benzene?
    3% 2C4-diene- (isothiocyanate) -benzene, when using it, you need to pay attention to many things.
    First, this material has certain toxicity, touching it, smelling it or eating it can endanger human health. When handling it, you must wear protective gear, such as gloves, masks, goggles, etc., to avoid contact with the skin, respiratory tract and eyes. And the operation should be in a well-ventilated place to prevent gas accumulation.
    Second, it is chemically active and easy to react with other substances. Therefore, when storing, avoid co-placing with strong oxidants, strong acids, strong alkalis, etc., to prevent unexpected chemical reactions. The storage vessel should also be sealed and placed in a cool and dry place. Do not let it be disturbed by light and heat to prevent it from deteriorating.
    Third, when using, it is essential to accurately control the dosage. Excessive use may cause excessive reaction, produce undesirable results, and may increase the risk of safety. Therefore, the appropriate dosage should be accurately calculated and weighed according to the needs of the reaction before use.
    Fourth, the waste related to this substance must not be disposed of at will. It must be collected in accordance with relevant regulations, sorted and properly disposed of to avoid polluting the environment. If there is residue after the reaction, or the used container needs to be properly disposed of before it can be discarded.
    In short, when using 3% 2C4-diene- (isothiocyanate) -benzene, care should be taken in terms of safety, storage, dosage, and waste disposal to ensure smooth operation and avoid accidents.