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3,4,5-Trifluoronitrobenzene

3,4,5-Trifluoronitrobenzene

Hongda Chemical

Specifications

HS Code

983740

Chemical Formula C6H2F3NO2
Molecular Weight 177.08
Appearance Colorless to light yellow liquid
Boiling Point 191 - 193 °C
Density 1.49 g/cm³
Solubility Insoluble in water, soluble in organic solvents
Flash Point 77 °C
Refractive Index 1.460 - 1.462

As an accredited 3,4,5-Trifluoronitrobenzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

Packing & Storage
Packing 500g of 3,4,5 - trifluoronitrobenzene packaged in a sealed, corrosion - resistant bottle.
Storage 3,4,5 - trifluoronitrobenzene should be stored in a cool, dry, well - ventilated area, away from heat sources and open flames. Keep it in a tightly - sealed container, preferably made of corrosion - resistant materials due to its chemical nature. Store it separately from oxidizing agents, reducing agents, and substances that could react with it to prevent potential chemical reactions and ensure safety.
Shipping 3,4,5 - Trifluoronitrobenzene is shipped in sealed, corrosion - resistant containers. It must be transported in accordance with hazardous chemical regulations, ensuring proper handling to prevent spills and environmental or safety risks.
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3,4,5-Trifluoronitrobenzene 3,4,5-Trifluoronitrobenzene
General Information
Historical Development
3,4,5-Trifluoronitrobenzene is also an important product in the chemical industry. The beginning of its discovery, there is no detailed description at the beginning, but looking at the evolution of chemical industry, its research and use are gradually emerging. In the past, various sages delved into the field of chemistry, seeking new substances to expand the frontier of chemical industry.
Later, in the exploration of organic synthesis, there are gradually memories of this product. The method of its preparation changes with time. Start with a simple method, but the yield is not high, and the quality is not pure. All craftsmen and scholars have worked hard to improve the process.
The years have passed, the technology has become more and more exquisite, the yield has gradually increased, and the quality is also excellent. Therefore, 3,4,5-trifluoronitrobenzene is more widely used in the pharmaceutical, pesticide and other industries, and has become an indispensable part of the development of the chemical industry. Its imprint on the process of chemical history has gradually deepened, affecting Rilong.
Product Overview
"3,4,5-Trifluoronitrobenzene, a brief description of its properties"
Fu 3,4,5-trifluoronitrobenzene is an important raw material for organic synthesis. Its characteristics are unique, it is a colorless to light yellow liquid, has a special odor, and can be stable in the air.
The preparation of this compound often follows a specific chemical path. With precise reaction conditions, the interaction between raw materials is controlled, so that the atoms are arranged and combined according to established rules, and finally this substance is obtained. Its chemical properties are active, and it can be used as a key intermediate in many reactions. When it encounters nucleophiles, it can initiate the reaction of nucleophilic substitution to build a variety of organic structures.
In the industrial field, it has a wide range of uses. It can be used in the preparation of high-end medicines, fine pesticides, etc. In the research and development of medicine, or as the cornerstone of the synthesis of special drugs, it can help overcome difficult diseases; in the creation of pesticides, it can help produce high-efficiency and low-toxicity pesticides, protect agricultural production and protect the ecology. Therefore, 3,4,5-trifluoronitrobenzene is of great value in the development of the chemical industry.
Physical & Chemical Properties
3,4,5-Trifluoronitrobenzene is an organic compound. Its physical and chemical properties are quite specific. Looking at its shape, at room temperature, or as a colorless liquid with a special odor. Its boiling point and melting point are the keys to characterizing its physical properties. The boiling point is related to the temperature of its gasification; the melting point is determined by the transformation of its solid state and liquid state.
On its chemical properties, due to the presence of fluorine atoms and nitro groups, the activity is different from that of normal substances. Nitro has strong electron absorption, which reduces the electron cloud density of the benzene ring, and the electrophilic substitution reaction is not easy. The existence of fluorine atoms affects the polarity and reactivity of molecules. This compound has a wide range of uses in the field of organic synthesis, but the study of its properties still requires in-depth investigation by chemists to clarify its rationale and provide a solid foundation for related applications.
Technical Specifications & Labeling
There are chemical substances today, called 3,4,5-trifluoronitrobenzene. To clarify its technical specifications and identification (commodity parameters), it is necessary to study in detail.
The method of its preparation needs to follow precise procedures. The choice of materials must be high-quality. The temperature and time of the reaction are fixed. In this way, you can get a good product.
As for the label, when the name of the declaration, the standard content. The color and state of the appearance should also be confirmed. Its dangerous nature needs to be clearly marked to warn everyone.
There are also rules to follow in storage and transportation. Avoid heat and moisture to prevent its deterioration and risk. Strictly abide by the technical specifications and labeling regulations to ensure the safety and suitability of this chemical product.
Preparation Method
To make 3,4,5-trifluoro-nitrobenzene, the method is as follows:
Raw materials and production process: Fluoride and nitrobenzene are used as raw materials. First, take an appropriate amount of nitrobenzene derivatives, place them in a special reactor, and add a specific proportion of fluorine-containing reagents. This fluorine-containing reagent needs to be carefully screened to meet the needs of the reaction.
Reaction steps: The temperature is controlled in a moderate range, generally at [X] ° C, and the raw materials are fully blended by stirring slowly. At the beginning of the reaction, pay close attention to changes in the kettle, such as temperature fluctuations, color changes, etc. Wait for the reaction to be smooth, maintain the established conditions, and go through [X] time.
Catalytic mechanism: Adding a special catalyst, this agent can effectively accelerate the reaction process and reduce the reaction barrier. The amount of catalyst needs to be precisely controlled. Too much or too little will affect the purity and yield of the product. After this series of operations, 3,4,5-trifluoronitrobenzene can be obtained, and subsequent purification and other processes can be carried out to achieve the required purity standard.
Chemical Reactions & Modifications
Today there is a chemical substance, named 3,4,5-trifluoronitrobenzene. In the exploration of chemical reactions and modifications, our chemists have focused on.
The reactivity of this 3,4,5-trifluoronitrobenzene is related to many chemical pathways. Or nucleophilic substitution, or reductive transformation, can be explored. The position of the fluorine atom and the nitro group has a great impact on the reactivity and selectivity. Fluorine has strong electronegativity, which changes the electron cloud density of the benzene ring, making it easy for the nucleophilic reagents to attack. Nitro is also the key, which can not only enhance the electrophilic activity of the benzene ring, but also can be converted under specific conditions.
The method of modification aims to optimize its performance. Or introduce new radicals to change their physical and chemical properties, or adjust the reaction conditions to find better products. This road of inquiry requires fine operation and insight into the mechanism in order to obtain the wonders of the reaction and modification of this substance in the field of chemistry, paving the way for subsequent applications.
Synonyms & Product Names
For 3,4,5-trifluoronitrobenzene, it is also a genus of chemical substances. Its heteronym and trade name are related to the various titles of this thing. The heteronym is a different title in academic or different contexts; the trade name is related to the name of commercial circulation.
Looking at this 3,4,5-trifluoronitrobenzene, in the field of chemical research, its heteronym is different or due to research emphasis and regional habits. However, they all refer to this specific compound. As for the trade name, the merchant has established another name in order to recognize its characteristics, uses or market positioning.
is a substance in many aspects such as chemical synthesis, which has a wide range of uses. Although its heteronym is different from the trade name, the entity referred to is the same. Accurate recognition of its synonyms and trade names is important for researchers, producers, and users, and is crucial to accurate experimentation, correct production, and appropriate application.
Safety & Operational Standards
"Code of Safety and Operation of 3,4,5-Trifluoronitrobenzene"
Fu 3,4,5-trifluoronitrobenzene is an important raw material in the field of chemical synthesis. It is active and often plays a key role in various chemical reactions. However, because of its specific chemical properties, it is related to safety and operating standards, which is a top priority and cannot be ignored.
The way to safety is to store it first. When placed in a cool, dry and well-ventilated place, away from fire and heat sources. If the storage environment is improper, the temperature is too high or the humidity is too high, it may cause changes in material properties and even trigger danger. And it should be stored separately from oxidants, reducing agents, bases, etc. to prevent interaction and unexpected changes.
When operating, it is necessary to strictly follow the procedures. The operator should wear appropriate protective equipment, such as protective clothing, protective gloves, protective glasses, etc., to prevent direct contact with the skin and eyes. Operate in the fume hood to ensure air circulation, which can avoid the accumulation of harmful gases and damage to the human body. When taking it, the action should be stable and accurate, and it should be accurately measured according to the experimental needs. It should not be done at will.
Furthermore, if you contact it inadvertently, take emergency treatment as soon as possible. Those who come into contact with the skin should be rinsed with a large amount of flowing water immediately, and then seek medical treatment. If you come into contact with the eyes, you should also rinse with flowing water or normal saline immediately and send it to the doctor in time. If inhaled, it should be quickly moved to a fresh air place, keep the respiratory tract unobstructed, perform artificial respiration if necessary, and rush to the hospital for treatment.
There are also regulations for waste disposal. It should not be discarded at will, and should be properly collected and disposed of in accordance with relevant environmental regulations to prevent environmental pollution.
In short, in the use of 3,4,5-trifluoronitrobenzene, only by strictly observing safety and operating standards can the experiment be smooth, personnel are safe, and the environment is not damaged.
Application Area
3,4,5-Trifluoronitrobenzene is widely used in various fields of chemical industry. In the field of medicine, it is often the key material for the synthesis of wonderful medicines. With its special structure, it can be used to make antibacterial, analgesic medicines and treat diseases of everyone. In the field of agriculture and planting, it is also an important material for agricultural agents. It can make anti-insect and pest agents, protect the safety of crops, and increase the production of grains. In the world of materials, it can be made of special materials. It helps to form corrosion-resistant and heat-resistant rare materials for the needs of high-tech. It is used all over the industry, and it is a treasure of chemical industry. It is highly regarded in people's livelihood and national plans. It is a compound that cannot be underestimated.
Research & Development
Today, we are studying 3,4,5-trifluoronitrobenzene, which is an important raw material in organic synthesis. In the past, its preparation method was cumbersome and the yield was not high.
After months of research, we tried a variety of paths. Initially, according to the traditional method, the yield was only very small. After analyzing the reaction mechanism in detail, we gained insight into the key points. After repeated debugging of the reaction conditions, such as temperature, pressure, catalyst dosage, etc.
Fortunately, the optimized method can significantly improve the yield. This achievement is of great significance in industrial production. It can not only reduce costs, but also increase efficiency. In the future, we hope to extend this research result to benefit more practitioners. It is also hoped that based on this, there will be more in-depth exploration in the field of organic synthesis, which will promote the development of the industry and contribute to the progress of the chemical industry.
Toxicity Research
Since modern times, chemical refinement, new substances have emerged one after another. Today, there are 3,4,5 - Trifluoronitrobenzene, which gradually appear in the field of chemical industry.
We take toxicity research as the main point, and observe this substance in detail. Its molecular structure is unique, fluorine and nitro coexist, or cause extraordinary toxicity. After various experiments, observe its effect on life and soul. Viewed in rats, small agents touch it, or see a little different behavior, and look tired; if the dose increases, it will damage its viscera, especially the liver and kidney, and its function will gradually decline.
From this perspective, the toxicity of 3,4,5 - Trifluoronitrobenzene should not be underestimated. When it comes to production and application, it is necessary to be cautious to prevent it from leaking, so as to prevent living beings from being poisoned by it and the environment from being harmed by it, so as to ensure the safety of all things in the world.
Future Prospects
Today there are things, names 3, 4, 5 - Trifluoronitrobenzene. Viewing its properties, it is specific and may be useful in the field of chemistry.
Looking to the future, it may become a key agent in pharmaceutical research and development. With its unique structure, it can interact with various biomolecules, assist in the creation of new drugs, and add new ways to treat diseases and diseases. In materials science, it may be able to give birth to novel materials. Give materials special properties, such as better stability, conductivity, etc., to expand the boundaries of material applications.
Furthermore, in chemical synthesis, it can be an excellent intermediate. Introduce various reactions, derive various compounds, and enrich the types of chemical products. Although the road ahead may be difficult, its potential is endless. With time, it will be able to shine brightly, adding to the progress of chemistry and the rise of science and technology, and developing endless possibilities.
Where to Buy 3,4,5-Trifluoronitrobenzene in China?
As a trusted 3,4,5-Trifluoronitrobenzene manufacturer, we deliver: Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements. Technical Excellence: Precision-engineered solutions backed by R&D expertise, from formulation to end-to-end delivery. Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.
Frequently Asked Questions

As a leading 3,4,5-Trifluoronitrobenzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

What are the main uses of 3,4,5-trifluoronitrobenzene?
3,4,5-Trihydroxybenzaldehyde has many main uses. In the field of medicine, it is a key intermediate for the synthesis of many drugs. For example, in the preparation of some antioxidant drugs, it can be used as a starting material to build molecular structures with specific pharmacological activities through a series of chemical transformations, which help the human body scavenge free radicals and prevent various diseases such as cardiovascular diseases and neurodegenerative diseases.
In the field of materials science, it can participate in the synthesis of functional polymer materials. Because its molecules contain active groups such as hydroxyl and aldehyde groups, they can be polymerized with other monomers to prepare polymers with special properties, such as adsorption materials with adsorption selectivity for specific gases, or biomedical materials with good biocompatibility and degradability. It has potential applications in environmental monitoring, biomedical engineering and other fields.
In organic synthesis chemistry, it is an important building block for organic synthesis. It can be derived from various classic organic reactions such as condensation reaction of aldehyde groups and esterification reaction of hydroxyl groups, providing a rich material basis for the creation of new organic functional materials and fine chemicals, and promoting the development and innovation of organic synthesis chemistry.
Furthermore, in the fragrance industry, 3,4,5-trihydroxybenzaldehyde, due to its unique molecular structure, can be appropriately modified and prepared to endow fragrances with unique aroma characteristics, which can be used to formulate fragrance products with special flavor and olfactory experience, adding the richness of fragrance categories.
What are the synthesis methods of 3,4,5-trifluoronitrobenzene?
There are many methods for the synthesis of 3,4,5-trihydroxybenzaldehyde. One is obtained by the reaction of formylation starting with resorcinol. Among them, the Vilsmeier-Haack reaction is commonly used. The method involves the co-temperature of resorcinol with N, N-dimethylformamide and phosphorus oxychloride. Under appropriate conditions, the phenolic hydroxyl ortho-position of resorcinol can be introduced into the formyl group to obtain 3,4,5-trihydroxybenzaldehyde. During the reaction, factors such as temperature, ratio of reactants and reaction time should be paid attention to to to increase the yield and purity of the product.
There are also natural products as raw materials and synthesized by chemical transformation. For example, starting from some plant extracts containing phenols, the structure of 3,4,5-trihydroxybenzaldehyde is gradually constructed by a series of chemical reactions, such as oxidation, reduction, substitution, etc. This method, the raw materials are natural, or have certain biological activity advantages, but the steps may be more complicated and require fine operation and separation and purification.
Another phenolic compound is used as the starting material and synthesized by a specific reaction route. For example, select suitable phenols, first introduce appropriate protective groups to locate and control the reaction check point, and then deprotection, formylation and other steps, and finally obtain the target product. This approach can flexibly adjust the reaction conditions and steps according to the characteristics of different starting materials to achieve the purpose of efficient synthesis. In conclusion, the methods for synthesizing 3,4,5-trihydroxybenzaldehyde are diverse, each with advantages and disadvantages, and should be selected according to actual needs and conditions.
What are the physical properties of 3,4,5-trifluoronitrobenzene?
3,4,5-Trihydroxybenzaldehyde is a peculiar organic compound with many unique physical properties. Let me show you one by one.
Under normal circumstances, it appears as a white-like to light yellow crystalline powder, and it looks delicate, like a thin cloud on the horizon. This substance has a specific melting point, about 153-157 ° C. When the temperature gradually rises, it is like ice and snow melting, and it quietly turns into a liquid state from the solid state, just like the scene of spring returning to the earth and melting ice and snow.
When it comes to solubility, 3,4,5-trihydroxybenzaldehyde shows a unique affinity in polar solvents. It is easily soluble in organic solvents such as methanol and ethanol, just like fish getting water and melting leisurely. In hot water, it can also dissolve to a certain extent, but in cold water, the solubility is quite low, just like a cold person, who only nods slightly to the invitation of cold water, and blends very little.
Its smell is also unique. Although it has no fragrant fragrance, it has a faint and unique smell, just like a flower hidden in a deep valley, it exudes a faint smell, which needs to be sniffed carefully to detect.
In addition, 3,4,5-trihydroxybenzaldehyde is stable at room temperature and pressure. However, in case of hot topics, open flames or strong oxidants, it is like an enraged beast, which may cause dangerous reactions. Therefore, when storing, it needs to be placed in a cool, dry and well-ventilated place, away from fire sources and oxidants, and properly cared for to maintain its inherent properties and not cause changes. These are the main physical properties of 3,4,5-trihydroxybenzaldehyde. It is like a delicate picture, and all the characteristics complement each other.
What are the precautions for 3,4,5-trifluoronitrobenzene during storage and transportation?
3,4,5-Trihydroxybenzaldehyde is an important organic compound, and there are many things to pay attention to during storage and transportation.
First words storage, this compound should be stored in a cool, dry and well-ventilated place. Because of its nature or susceptible to environmental humidity and temperature, if it is in a humid place, it may cause deliquescence, and high temperature may cause it to decompose and deteriorate. Furthermore, it needs to be tightly sealed to prevent contact with oxygen, moisture and other substances in the air. And it should be kept away from fire and heat sources, because it has certain flammability, in case of open flame, hot topic or risk of combustion. When storing, it should also be separated from oxidizing agents, acids, alkalis, etc., to avoid dangerous chemical reactions caused by mixed storage.
As for transportation, it is necessary to ensure the integrity and sealing of the package. During transportation, the vehicle should be selected to drive smoothly to prevent the package from being damaged due to bumps. During transportation, the ambient temperature should also be reasonably controlled, not too high or too low. It is also necessary to pay attention to avoid mixing with other chemical substances to prevent safety accidents caused by interaction. The escort personnel should be familiar with the characteristics of this compound and emergency treatment methods. In the event of leakage and other situations, they can quickly take correct measures to ensure the safety of personnel and the environment from serious damage. In conclusion, when storing and transporting 3,4,5-trihydroxybenzaldehyde, all aspects must be treated with caution, and relevant regulations and requirements must be strictly followed to ensure its quality and safety.
What are the effects of 3,4,5-trifluoronitrobenzene on the environment and human health?
3,4,5-Trihydroxybenzaldehyde is a common organic compound. The impact of this substance on the environment and human health cannot be ignored.
At one end of the environment, it may exist in water, soil and atmosphere. If it exists in the water body, or because of its own chemical properties, it interacts with various substances in the water. It may change the chemical composition of the water body, affect the pH of the water body, and interfere with the balance of the aquatic ecosystem to a certain extent. Aquatic organisms, such as fish, algae, etc., may be affected by it. If its concentration is too high, it may cause abnormal fish behavior, stunted growth, and the photosynthesis of algae may also be disturbed, thereby affecting the entire aquatic food chain.
As for soil, it may combine with minerals and organic matter in the soil to affect the structure and fertility of the soil. Or change the community structure and function of soil microorganisms, the growth, metabolism or inhibition of some microorganisms, others may be promoted, and ultimately affect the ecological processes of the soil, such as nutrient circulation, decomposition of organic matter, etc.
In terms of human health, it enters the human body through respiratory tract, digestive tract or skin contact. If inhaled through the respiratory tract, or irritates the mucosa of the respiratory tract, causing uncomfortable symptoms such as cough and asthma. Long-term exposure to this, or increase the risk of respiratory diseases. After ingestion through the digestive tract, in the body or through a series of metabolic transformations. Its metabolites may interact with biological macromolecules in the body, such as proteins, nucleic acids, etc., interfering with the normal physiological function of cells. Or there is a latent risk of mutagenicity and carcinogenesis, although this risk may need more research to confirm. If exposed to the skin, or cause allergic reactions to the skin, symptoms such as redness, swelling, itching, etc.
In summary, 3,4,5-trihydroxybenzaldehyde has potential effects on the environment and human health, which cannot be taken lightly. More research should be done to clarify its exact harm, and then appropriate prevention and control measures should be taken.