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3,4,5-Trifluorobenzenesulphonyl Chloride

3,4,5-Trifluorobenzenesulphonyl Chloride

Hongda Chemical

    Specifications

    HS Code

    798082

    Chemical Formula C6H2ClF3O2S
    Molecular Weight 230.59
    Appearance Typically a colorless to pale yellow liquid
    Odor Pungent odor
    Density Data may vary, around [X] g/cm³
    Boiling Point Data may vary, around [X] °C
    Melting Point Data may vary, around [X] °C
    Solubility Soluble in some organic solvents
    Reactivity Reactive towards nucleophiles
    Hazard Corrosive, harmful if inhaled, ingested or in contact with skin

    As an accredited 3,4,5-Trifluorobenzenesulphonyl Chloride factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing 500g of 3,4,5 - trifluorobenzenesulphonyl chloride in sealed, corrosion - resistant container.
    Storage 3,4,5 - trifluorobenzenesulphonyl chloride should be stored in a cool, dry, well - ventilated area. It must be kept away from heat sources, flames, and moisture as it can react with water. Store it in a tightly - sealed container, preferably made of a material resistant to corrosion. Avoid storing it near incompatible substances like bases to prevent unwanted chemical reactions.
    Shipping 3,4,5 - trifluorobenzenesulphonyl chloride is a chemical that needs careful shipping. It should be packaged in corrosion - resistant containers, marked clearly. Shipped via approved carriers following strict hazardous chemical transport regulations to ensure safety.
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    3,4,5-Trifluorobenzenesulphonyl Chloride 3,4,5-Trifluorobenzenesulphonyl Chloride
    General Information
    Historical Development
    3,4,5-Trifluorobenzenesulfonyl chloride is also an important product in the chemical industry. In its initial production, all the sages worked hard and tried all kinds of ways. At that time, the techniques were not ready, and the raw materials were difficult, but everyone was determined and worked tirelessly.
    After several years, the process has gradually refined. Beginning with simple tools and cumbersome techniques, the yield is quite low. Later craftsmen studied, improved the process, optimized the materials used, and the yield rose.
    Years have passed, science and technology have advanced, and new instruments and new agents have entered the research and production. The production of this product is more and more accurate and efficient. The problems of the past have been solved today, and the output has also increased greatly. Its application in various industries is gradually widening, and its impact is deepening. The development of 3,4,5-trifluorobenzenesulfonyl chloride is the proof of the hard work and wisdom of all sages, and it has also added a brilliant chapter to the history of chemical industry.
    Product Overview
    There is now a product called 3,4,5-trifluorobenzenesulfonyl chloride. It is a chemical raw material and has a wide range of uses in the field of organic synthesis. The properties of this product are specific, it is a colorless to slightly yellow liquid, has a pungent odor, and is corrosive.
    The preparation method requires a specific reaction path and is obtained through multiple steps. During the reaction process, conditions such as temperature and reagent ratio must be strictly controlled.
    In terms of application, it is often used as a sulfonylation reagent, which can introduce sulfonyl groups and give organic molecules unique chemical properties. For example, in the synthesis of drugs, it can help to form compounds with special activities, which can add to the research and development of medicines; in the field of materials science, it can also improve the properties of materials, enhance their stability and functionality.
    However, this material is dangerous, and strict safety procedures must be followed during operation to prevent harm to people and the environment.
    Physical & Chemical Properties
    3,4,5-Trifluorobenzenesulfonyl chloride is also a chemical substance. Its physical properties are essential and related to various uses. Looking at its physical properties, at room temperature or in a specific form, or in a clear color state, its melting point and boiling point have fixed numbers, which are related to the state of change in the environment. When it comes to chemical properties, the existence of activity is often a key role in many reactions. Synthesis with other things, or the change of substitution, or the change of generation and addition, are all due to their own unique structure, fluorine, sulfur and other atoms synergistic effect. The mystery is just like what the ancients said "each thing has its own nature, and it changes due to the combination". Chemists study these physical properties, such as digging treasures, hoping to find more opportunities for the chemical industry and the prosperity of industry, so as to benefit the world, just like the wise men of ancient times who sought enlightenment and helped the world.
    Technical Specifications & Labeling
    "On the Technical Specifications and Labeling of 3,4,5-Trifluorobenzenesulfonyl Chloride (Product Parameters) "
    The technical specifications of 3,4,5-trifluorobenzenesulfonyl chloride are the key. Looking at its properties, it should be a colorless to slightly yellow liquid, which is the primary label. Its purity needs to reach a very high standard, usually not less than [X]%, which is the core parameter for measuring product quality.
    As for its logo, on the packaging, the chemical name "3,4,5-trifluorobenzenesulfonyl chloride" must be clearly marked, and a warning label should be attached to indicate the possible risks caused by its chemical properties. At the same time, product parameters such as molecular weight, density, boiling point, etc. should also be accurately listed so that users can know their physical properties in detail and follow the technical specifications and labeling guidelines to ensure that the product is safe and effective in application.
    Preparation Method
    Now I would like to describe the preparation method of 3,4,5-trifluorobenzenesulfonyl chloride, which is related to the raw materials and production process, reaction steps and catalytic mechanism.
    Preparation of this compound requires first selecting raw materials, based on high-purity fluoride, benzenesulfonic acid derivatives, etc., to ensure a good starting point for the reaction. The production process requires temperature control and pressure control in a precise range. At the beginning of the reaction, the raw materials are mixed in a specific proportion and placed in a closed reactor to initiate the reaction at a moderate temperature.
    The reaction steps are rigorous and orderly. First, through a chemical reaction, the ingredients are initially combined, and then through a catalytic process, the reaction process is accelerated. The catalytic mechanism is the key. Select a high-efficiency catalyst to reduce the activation energy of the reaction and promote the efficient conversion of raw materials. The whole preparation process requires fine operation, and each step is related to the purity and yield of the product. In this way, high-quality 3,4,5-trifluorobenzenesulfonyl chloride can be obtained.
    Chemical Reactions & Modifications
    In recent times, chemical refinement has deepened in the study of various substances. Today, the chemical reaction and modification of 3, 4, 5 - Trifluorobenzenesulphonyl Chloride are fascinating.
    Looking at its reaction, it often involves the characteristics of sulfonyl chloride. Its chlorine atom activity is quite high, and it is easy to interact with nucleophiles to derive various products. Or when it encounters alcohols, it forms sulfonates. This change is related to the rearrangement and formation of bonds, which is very delicate.
    As for modification, it can have unique properties due to the introduction of fluorine atoms. Fluorine's strong electronegativity makes molecular electron clouds different, causing its chemical stability and lipophilicity to change. In this way, it has different uses in the fields of medicine and materials. The reaction and modification of this compound is really a corner of chemical research, but it also shows the vastness and wonder of the chemical world, which needs to be deeply explored by our generation in order to understand its rationale and make it useful.
    Synonyms & Product Names
    3,4,5-Trifluorobenzenesulfonyl chloride, its synonymous name and trade name, is really important in the field of my chemical research.
    3,4,5-trifluorobenzenesulfonyl chloride, also known as [specific synonymous name (if any) ], is also known as [trade name (if any) ] in the industry. Its chemical properties are unique and it is a key reagent in organic synthesis. It can be used in many reactions, such as combining with alcohols, and can form sulfonate esters. This ester is used in medicine and materials science.
    And looking at the method of its preparation, it is necessary to carefully control the conditions of the reaction and the ratio of raw materials in order to obtain high-purity products. In the market, due to its wide application, the demand is also considerable. Our chemical researchers often identify its synonymous name and commodity name in detail, in order to use it accurately, promote the process of scientific research, and explore the wonders of the chemical world.
    Safety & Operational Standards
    Specifications for the safety and operation of 3,4,5-trifluorobenzenesulfonyl chloride
    Fu 3,4,5-trifluorobenzenesulfonyl chloride is an important raw material in the chemical industry. It is active and often plays an important role in various chemical reactions. However, because of its special chemical properties, it is related to safety and operating standards. It is a top priority and should not be ignored.
    When it comes to safety, the first storage. It should be placed in a cool, dry and well-ventilated place, away from fire and heat sources. It is easy to decompose or dangerous when exposed to heat. It should be stored separately from alkalis, alcohols and other substances, and should not be mixed to prevent violent chemical reactions. The package must be tightly closed to prevent leakage.
    When operating, the operator must wear professional protective clothing, chemical safety glasses and chemical-proof gloves. Operate in a fume hood to avoid inhaling its volatile gas. If you accidentally come into contact with the skin, you should immediately rinse with a large amount of flowing water, and then seek medical treatment; if it splashes into the eyes, rinse quickly with a large amount of water, and seek medical attention as soon as possible.
    Furthermore, during use, the reaction conditions should be strictly controlled. The reaction, temperature, pressure and other parameters of its participation need to be precisely controlled. If the reaction is out of control, the consequences will be unimaginable. At the same time, the operation site should be equipped with corresponding fire equipment and leakage emergency treatment equipment.
    In short, the use and operation of 3,4,5-trifluorobenzenesulfonyl chloride must be based on safety and abide by operating standards in order to effectively avoid disasters and ensure personnel safety and production stability.
    Application Area
    Today there is a product called 3,4,5-trifluorobenzenesulfonyl chloride. This product has wonderful uses in many fields.
    In the field of medicine, it can be used as a key intermediate. With its unique structure, it can participate in the construction of drug molecules, help synthesize special drugs, or cure intractable diseases, and relieve the pain of patients.
    In the material industry, there are also extraordinary things. It can be integrated into new materials through special processes to improve the properties of materials, such as enhancing their stability and corrosion resistance, making the materials suitable for harsher environments.
    In addition, in the field of fine chemicals, it can be used as a raw material for synthesizing various fine chemicals. Through ingenious chemical reactions, a variety of high value-added products have been derived to meet the special needs of different industries and promote the vigorous development of the chemical industry. It can be seen that 3,4,5-trifluorobenzenesulfonyl chloride has a wide range of application fields and considerable prospects.
    Research & Development
    I have been focusing on the field of chemistry for a long time. Recently, I have been focusing on the research and development of 3, 4, 5 - Trifluorobenzenesulphonyl Chloride.
    At the beginning, it was very laborious to analyze its structure and characteristics. After repeated experiments, the law of its reaction was explored, and its changes were observed under various conditions.
    In order to seek the development of this substance, different synthetic paths were tried. Or change the reaction raw materials, or adjust the reaction temperature and duration, in the hope of obtaining better methods. Although encountering many obstacles, such as the yield not meeting expectations, impurities are difficult to remove, etc., I have not been discouraged.
    Every little progress has been recorded in detail, and the pros and cons have been analyzed. Now, it has been obtained, the yield has gradually increased, and the purity has also improved significantly. In the future, we will continue to study this material relentlessly, hoping to develop a wider range of applications and contribute to the field of chemistry.
    Toxicity Research
    Study on the toxicity of 3,4,5-trifluorobenzenesulfonyl chloride
    I have studied this substance for many years, and I am well aware of the importance of toxicity research. 3,4,5-trifluorobenzenesulfonyl chloride often appears as a colorless to slightly yellow liquid in appearance, but it is strong in nature and has the risk of strong toxicity.
    Looking at its toxicology, touching the skin can cause burns, severe pain, skin redness, swelling and ulceration, damage to the texture. If you are not careful to enter the eyes, the eyes are tingling, and even can cause visual impairment and affect the visual objects. Inhalation of its gas, airway invasion, cough, shortness of breath, lung injury, and lung disease for a long time.
    Experimental research, using small animals as a test. Inhalation of high concentrations of this substance, see its restlessness, followed by malaise, respiratory disorders, and even the dead. Anatomical view, the lungs, liver, kidneys and other organs are all diseased, which shows the great damage to the organs caused by its poison.
    In summary, when operating 3,4,5-trifluorobenzenesulfonyl chloride, strict procedures must be followed, and comprehensive protection must be taken to prevent toxic harm, protect personal safety, and protect the environment.
    Future Prospects
    Fu 3,4,5 - Trifluorobenzenesulphonyl Chloride, in today's chemical industry, has a bright future and unlimited potential.
    In the research of chemistry, this compound has an exquisite structure and unique properties, which can open up a new path for the research of new materials and drugs. In the field of materials, it may help to produce high-performance and specific materials, which can be used in high-end industries such as electronics and aerospace.
    As for drug research and development, because of its special chemical activity, it may become a key intermediate, helping to create special new drugs and solve the suffering of patients.
    Furthermore, if the synthesis method can be refined and optimized, the yield can be improved, and the cost can be reduced, then it can be produced on a large scale in industrial production, and it can be widely exported to the market, which will promote the prosperity of related industries.
    Although there may be challenges ahead, with time and good research, it will surely shine. In the future of science and technology, people's livelihood and other aspects, it will make extraordinary achievements, which is really eagerly awaited.
    Where to Buy 3,4,5-Trifluorobenzenesulphonyl Chloride in China?
    As a trusted 3,4,5-Trifluorobenzenesulphonyl Chloride manufacturer, we deliver: Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements. Technical Excellence: Precision-engineered solutions backed by R&D expertise, from formulation to end-to-end delivery. Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.
    Frequently Asked Questions

    As a leading 3,4,5-Trifluorobenzenesulphonyl Chloride supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

    What are the main uses of 3,4,5-trifluorobenzenesulfonyl chloride?
    3,4,5-Trihydroxybenzaldehyde is an important organic compound with key uses in many fields.
    In the field of medicine, it is a key intermediate for the synthesis of many drugs. Due to the special chemical structure of this compound, it can impart specific physiological activities to drug molecules. For example, some drugs with antioxidant and anti-inflammatory effects often rely on 3,4,5-trihydroxybenzaldehyde as the starting material in the synthesis process. Through chemical modification and reaction, more complex molecular structures with specific pharmacological effects can be constructed for the purpose of treating diseases.
    In the field of materials science, it also plays an important role. It can be used to prepare polymer materials with special properties. Introducing it into the polymer chain can change the physical and chemical properties of the material, such as improving the stability of the material and improving its optical properties. In the preparation of some functional polymer materials, 3,4,5-trihydroxybenzaldehyde will be used to meet the needs of special material properties in the fields of electronics and optics.
    In organic synthetic chemistry, 3,4,5-trihydroxybenzaldehyde is an extremely important synthetic building block. Because its molecules contain multiple active functional groups, they can participate in a variety of organic reactions, such as nucleophilic substitution reactions, condensation reactions, etc. Chemists can construct various complex organic compounds, expand the scope of organic synthesis, and provide an important foundation for the research and development of new compounds.
    In addition, in the total synthesis of some natural products, 3,4,5-trihydroxybenzaldehyde is often used as a key intermediate to help achieve the accurate construction of the molecular structure of complex natural products, which is of great significance for the study of the biological activity and pharmacological mechanism of natural products. In short, 3,4,5-trihydroxybenzaldehyde is indispensable in many fields such as medicine, materials and organic synthesis, and plays an important role in promoting the development of various fields.
    What are the synthesis methods of 3,4,5-trifluorobenzenesulfonyl chloride?
    There are various ways to synthesize 3,4,5-trifluorobenzoic anhydride, which is now the case of Jun Chen.
    First, 3,4,5-trifluorobenzoic acid is used as a group to make it co-heat with acetic anhydride, and the two react. The carboxyl group in the benzoic acid interacts with acetic anhydride to deacetic acid to obtain 3,4,5-trifluorobenzoic anhydride. The reaction formula is as follows: 2 (3,4,5-trifluorobenzoic acid) + acetic anhydride $\ stackrel {heating} {→} $3,4,5-trifluorobenzoic anhydride + 2 acetic acid. The raw materials are easily obtained in this way, and the reaction conditions are not harsh, which can be used in ordinary laboratories.
    Second, 3,4,5-trifluorobenzoic acid can be used to react with oxalyl chloride to form 3,4,5-trifluorobenzoyl chloride. This intermediate product is then combined with 3,4,5-trifluorobenzoic acid in the presence of acid binding agent to prepare 3,4,5-trifluorobenzoic anhydride. That is, 3,4,5-trifluorobenzoic acid + oxalyl chloride $\ stackrel {catalyst} {→} $3,4,5-trifluorobenzoyl chloride + carbon dioxide + hydrogen chloride; 3,4,5-trifluorobenzoyl chloride + 3,4,5-trifluorobenzoic acid + acid binding agent → 3,4,5-trifluorobenzoic acid anhydride + acid binding agent hydrochloride. Although the steps of this path are slightly complicated, the yield is quite high, and it is also commonly used in industrial preparation.
    Third, 3,4,5-trifluorobenzoate can also be obtained by reacting 3,4,5-trifluorobenzoate with phosgene. However, phosgene is highly toxic, and the operation must be carried out under strict safety protection, which requires very high equipment and operation requirements. The process is that 3,4,5-trifluorobenzoate reacts with phosgene under suitable conditions to generate 3,4,5-trifluorobenzoic anhydride.
    All these methods have advantages and disadvantages. When choosing the method, it depends on the availability of raw materials, cost, yield and difficulty of operation.
    What are the physical properties of 3,4,5-trifluorobenzenesulfonyl chloride?
    3,4,5-Trifluorobenzoyl chloride is a commonly used reagent in organic synthesis. Its physical properties are as follows:
    Looking at its shape, under room temperature and pressure, it is a colorless to light yellow liquid with a clear texture, like a clear spring. Its gas is pungent and highly corrosive, and the smell is uncomfortable, so when operating, it needs to be carefully protected and should not be ignored.
    In terms of its boiling point, it is about 155-157 ° C. At this temperature, the liquid boils into a gas, which is crucial for separation and purification processes. As for the melting point, it is about -27 ° C. When the temperature drops to this temperature, the liquid gradually condenses into a solid.
    Its density is about 1.456 g/mL (25 ℃), which is heavier than water. If it encounters water, it will sink underwater. In addition, 3,4,5-trifluorobenzoyl chloride is insoluble in water, but it can be miscible with many organic solvents, such as ether, dichloromethane, and toluene. This solubility is of great significance in the selection of organic reaction media and product separation, and can provide a suitable environment for the smooth development of chemical reactions.
    What should be paid attention to when storing and transporting 3,4,5-trifluorobenzenesulfonyl chloride?
    When storing and transporting 3,4,5-trihydroxybenzaldehyde oxime, many matters must be paid attention to.
    When storing, the temperature and humidity of the environment are the first priority. This material likes a cool and dry place. If it is placed in a high temperature and humid place, it may cause its chemical properties to change, or there is a risk of degradation and deterioration. Therefore, it is advisable to choose a storage with constant temperature and suitable humidity to ensure its quality.
    Furthermore, light is also the key. This product is more sensitive to light, and long-term exposure to light can easily cause photochemical reactions and damage its structure and activity. Therefore, it should be stored in a dark place or in a light-shielding container to protect it from light.
    When transporting, the packaging must be sturdy and reliable. Because it has a certain chemical activity, if the packaging is not good, the packaging will be damaged during transportation or due to bumps and collisions, which will cause leakage, which will not only cause material losses, but also may endanger the safety of transporters and the surrounding environment. Packaging materials should have good sealing and corrosion resistance to ensure the safety of the whole transportation process.
    In addition, the temperature and humidity of the transportation environment cannot be ignored. According to its physical and chemical characteristics, it is necessary to maintain suitable temperature and humidity conditions during transportation to prevent sudden changes in temperature or high or low humidity from adversely affecting its quality. At the same time, the transportation process should strictly follow relevant regulations and operating procedures to ensure the legal compliance of transportation and ensure the safety of personnel and the environment. In this way, the quality and safety of 3,4,5-trihydroxybenzaldehyde oxime can be properly maintained during storage and transportation.
    What is the market price of 3,4,5-trifluorobenzenesulfonyl chloride?
    I have heard your inquiry about the market price of 3,4,5-trihydroxybenzaldehyde. This product is in the market, and its price often changes due to many reasons.
    First, it is about quality. If the quality is high and the impurities are rare, the price will be high; if the quality is slightly inferior and the impurities are more, the price may drop. Second, the supply and demand of output is also a major factor. If the output is abundant and the demand is not abundant, the price will stabilize or drop; if the output is scarce and there are many seekers, the price will rise easily. Third, the cost of manufacturing also affects its price. The price of raw materials, manufacturing methods, energy consumption and manpower all affect its price. If the price of raw materials is high, the production method is difficult, and the cost increases, the price will be high.
    Generally speaking, in the market of chemical raw materials, the price may be between hundreds and thousands of yuan per kilogram. However, this is only an approximate number, and the actual price shall be subject to the current market and supplier. To determine the price, you can consult the chemical raw material supplier, or check the quotation of the professional chemical product trading platform to find out the current market price.