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3,4,5-Trifluorobenzenesulfonyl Chloride

3,4,5-Trifluorobenzenesulfonyl Chloride

Hongda Chemical

    Specifications

    HS Code

    866002

    Chemical Formula C6H2ClF3O2S
    Molecular Weight 230.59
    Appearance Typically a colorless to pale yellow liquid
    Physical State At Room Temperature Liquid
    Boiling Point Data may vary, generally in a certain range depending on purity
    Melting Point Specific value depends on purity and conditions
    Density Specific density value relevant to its liquid state
    Solubility Soluble in some organic solvents
    Vapor Pressure Characteristic vapor pressure value
    Stability Can be reactive, sensitive to moisture and certain substances
    Hazard Class Corrosive, may cause burns to skin and eyes

    As an accredited 3,4,5-Trifluorobenzenesulfonyl Chloride factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing 100 - gram vial of 3,4,5 - trifluorobenzenesulfonyl chloride, well - sealed for protection.
    Storage 3,4,5 - trifluorobenzenesulfonyl chloride should be stored in a cool, dry, well - ventilated area, away from heat and ignition sources. It should be kept in a tightly - sealed container, preferably made of corrosion - resistant materials due to its reactive nature. Store it separately from incompatible substances like oxidizing agents, bases, and moisture - containing materials to prevent dangerous reactions.
    Shipping 3,4,5 - trifluorobenzenesulfonyl chloride is a hazardous chemical. It should be shipped in accordance with strict regulations, using specialized containers. Ensure proper labeling and handling to prevent spills and ensure safe transportation.
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    3,4,5-Trifluorobenzenesulfonyl Chloride 3,4,5-Trifluorobenzenesulfonyl Chloride
    General Information
    Historical Development
    The industry of chemical industry is changing with each passing day, and the research of substances is full of fun. Today there are 3, 4, 5 - Trifluorobenzenesulfonyl Chloride, which began to appear. It was the sages who worked hard and tried hard. In the experimental environment, they repeatedly pushed for it. At the beginning, only a small amount was obtained, the performance was unknown, and the use was not obvious.
    However, the road of scientific research, although full of thorns, the aspiring people did not stop. After years of delay, the researchers used their efforts to improve their techniques and optimize the process. Gradually, the yield of this product has been promoted, the characteristics are clear, and it has emerged in the fields of medicine and materials, and its use is becoming more and more widespread.
    From the ignorance of the past to the present day, the development of 3, 4, 5 - Trifluorobenzenesulfonyl Chloride is a witness to the progress of scientific research, and also paves the way for future chemical innovation, which makes my generation look forward to it, and I hope that it will bloom again in various fields.
    Product Overview
    There is a substance called 3,4,5-trifluorobenzenesulfonyl chloride. This is a key reagent for organic synthesis. It may be a colorless to pale yellow liquid with a stimulating smell.
    Looking at its structure, there are trifluoro groups and sulfonyl chloride groups attached to the benzene ring, which give it unique chemical activity. The trifluoro group has strong electron absorption, which reduces the electron cloud density of the benzene ring and makes the sulfonyl chloride group more likely to participate in nucleophilic substitution reactions.
    In the field of organic synthesis, it has a wide range of uses. It can react with alcohols to prepare sulfonates, which is an important step in building an organic molecular skeleton; it can also react with amines to form sulfonamides, which are of great concern in medicinal chemistry and materials science.
    However, this substance is corrosive and toxic. When operating, you need to be careful and wear protective equipment in a well-ventilated place to prevent injury.
    Physical & Chemical Properties
    3,4,5-Trifluorobenzenesulfonyl chloride is also an organic compound. Its physical and chemical properties are related to many aspects. Looking at its properties, it is often in the state of a colorless to slightly yellow liquid, which is relatively stable at room temperature. However, it may react in case of heat or open flame, so it should be handled with caution.
    On its solubility, it can be soluble in a variety of organic solvents, such as ether, dichloromethane, etc. This property helps it to be used as a reactant or solvent in organic synthesis reactions. Its boiling point and melting point have fixed numbers. The value of the boiling point is determined according to the experiment, and it is in a specific range. The melting point is also marked accordingly.
    In addition, its chemical properties are active, and the sulfonyl chloride group is easily substituted with nucleophiles. It can be introduced into other compounds and has a wide range of uses in drug synthesis, materials science and other fields. Through this, a variety of products with specific properties can be prepared, making a lot of contributions to the development of chemical industry.
    Technical Specifications & Labeling
    "On the Technical Specification and Identification of 3,4,5-Trifluorobenzenesulfonyl Chloride (Product Parameters) "
    There are 3,4,5-trifluorobenzenesulfonyl chloride today, and its technical specifications are related to the preparation method. It is necessary to use a precise process to control the temperature and time of the reaction, and select the appropriate raw materials in an appropriate proportion to make the reaction smooth. The preparation environment should also be clean to prevent impurities from mixing and causing quality damage.
    In terms of identification, the product parameters must be clear. Mark it with the name "3,4,5-trifluorobenzenesulfonyl chloride" and list the number of purity to prove the quality. Also remember the physical and chemical properties, such as color, state, melting point, etc. And the standard storage method, depending on its nature, may need to be protected from light, moisture-proof, and low temperature to ensure its stability for later use, which is also essential for technical specifications and labeling.
    Preparation Method
    The method of preparing 3,4,5-trifluorobenzenesulfonyl chloride is crucial to the raw materials and production process, reaction steps and catalytic mechanism.
    The raw materials need to be carefully selected. Find suitable fluoroaromatic hydrocarbons, coupled with specific sulfonating reagents, the proportion and purity of the two are exquisite, which is the basis for the reaction.
    In the production process, the control of the reaction environment is extremely important. The temperature needs to be stable in a certain range, or under moderate heating, so that the reaction can be advanced in an orderly manner. The reaction steps are also complicated. First, the raw materials are put into a special reactor in sequence, stirred evenly, and then mixed initially. Then the catalysts are added in sequence.
    The catalytic mechanism is the key to accelerating the reaction. Selecting the appropriate catalyst can change the chemical reaction path, reduce the activation energy, and promote the efficient occurrence of the reaction. After various operations, careful separation and purification, pure 3,4,5-trifluorobenzenesulfonyl chloride products can be obtained to meet the needs of all parties.
    Chemical Reactions & Modifications
    Yu Taste Yan 3, 4, 5-Trifluorobenzenesulfonyl Chloride This substance, its chemical reaction and modification, has many thoughts.
    Its reaction is also strong and changeable. Combined with various substances, strange things often occur. In the way of nucleophilic substitution, halogen ions, hydroxyl groups, etc. tend to form new bonds, form new substances, like stars, and show the beauty of chemistry. However, its intensity also needs to be carefully controlled. Temperature, pressure, and the amount of agent are all about success or failure.
    As for modification, you can add groups to adjust its properties. Or increase its solubility, or change its stability. If the craftsman crafts jade, fine grinding. Adding an aryl group can strengthen its conjugation and change its light and electricity properties; adding an alkyl group can adjust its affinity and remoteness, and it is suitable for different situations.
    All these are the charm of chemistry. Between reaction and modification, explore new realms of matter, seek unknown possibilities, and unremitting research, hoping to obtain more wonders of creation.
    Synonyms & Product Names
    3,4,5-Trifluorobenzenesulfonyl chloride, the synonym and trade name of this substance, is really related to the important matter of our generation of chemical research. Let's discuss it in detail today.
    Fu 3,4,5-trifluorobenzenesulfonyl chloride has a prominent position in the field of chemical synthesis. Although there are many synonyms, they all refer to the same substance. Some are named after their chemical structure characteristics, and some are named according to their properties and uses. As for trade names, merchants have their own names, or they are easy to remember, or they are trying to show their characteristics.
    Although there are many synonyms and trade names, the essence is 3,4,5-trifluorobenzenesulfonyl chloride. In organic synthesis, it is often a key reagent, can participate in many reactions, and is an important part of the preparation of compounds with special structures. Our chemical researchers, when using it, must distinguish its synonyms and trade names to avoid confusion, ensure the accuracy of research, promote the progress of chemical research, and contribute to the prosperity of science.
    Safety & Operational Standards
    3,4,5-Trifluorobenzenesulfonyl chloride is also used in chemical products. In order to investigate its safe operation, it is necessary to increase the degree of corrosion.
    This thing has the property of corrosion, and if it is damaged or violated, it will also suffer from it. Therefore, when handling it, keep protective equipment, such as corrosion-resistant clothing, gloves, and eyes, to protect yourself.
    It is in the air, or in the biochemical environment, to create harmful waste. The room where it is placed must be passed through, so that the poison can be dispersed, so as not to gather and cause damage. And do not approach fire sources and coal sources to prevent ignition and explosion. If this product encounters water, the reaction will be strong, so it will be stored, and it will seek dryness.
    Use it, the equipment must be stale and dry, the operation is not urgent, and do not be impatient. Take the amount and take the essence to meet the needs.
    If you are not careful about your body, quickly use a lot of water to treat it. If there is any leakage, first remove the source, and then according to its nature, clean up carefully, and do not allow the stain to spread.
    In this case, handle 3,4,5-trifluorobenzenesulfonyl chloride to ensure safety and follow the operation. Only then can you avoid risks and ensure people's safety and physical integrity.
    Application Area
    Wenfu 3, 4, 5 -Trifluorobenzenesulfonyl Chloride This substance has a wide range of uses. In the field of medicine, it can be used as a key material for the synthesis of wonderful medicines. With its unique properties, it can make a good medicine to resist diseases and remove diseases for the sick.
    In the field of materials, it also has extraordinary uses. It can help develop new materials, make materials specific, or increase their strength, or add their toughness, or give them unique chemical stability. It is widely used in many industries.
    In the process of chemical synthesis, it is an important reagent. It can trigger delicate reactions, shape complex molecular structures, expand the possibility of synthesis, and make chemical technology even better. These are all 3, 4, 5 -Trifluorobenzenesulfonyl the application field of Chloride, which is indispensable for chemical, pharmaceutical, materials and other industries.
    Research & Development
    Modern chemistry has been refined, and all kinds of new substances have emerged one after another. I focus on the research of 3, 4, 5 - Trifluorobenzenesulfonyl Chloride. When I first studied its properties, I felt that its reaction was specific, and it had great potential in organic synthesis.
    After months of study, I tried to explore its changes in various ways. Looking at its combination with various reagents, whether warm or strong, various new substances are formed. Every time I get it, I record it in detail, think about it, and investigate its source.
    And seek to increase its yield and improve the process. After many adjustments, the process is gradually improved, and the yield is also increasing.
    However, the research path is not smooth, and every time I encounter a problem, I devote myself to it. Or refer to ancient books, or visit colleagues, in order to solve doubts.
    Now the research of this substance has gradually become successful. Hope that it can be widely used in medicine and materials in the future, and develop its growth, which will contribute to the progress of chemistry.
    Toxicity Research
    Recently, I have been studying the toxicity of "3, 4, 5 - Trifluorobenzenesulfonyl Chloride". This is the priority of chemical research, which is related to the health of all beings and the safety of the environment.
    After many inquiries, we have the first clue. It has certain toxicity and may have various effects on biological bodies. Look at its interaction with biological cells, or disturb the normal metabolism of cells, causing changes in physiological functions.
    The depth of toxicity depends on many factors. The dose and duration of exposure, the type and constitution of organisms are all related to it. Exposure to high doses may cause serious harm, while long-term exposure to low doses should not be underestimated, or lead to chronic diseases.
    In the future, we should use rigorous methods to deeply explore its toxicity mechanism, understand its chain reaction in the ecosystem, and hope to find a good strategy for protection and governance, so as to protect the world from its harm and keep the environment clean.
    Future Prospects
    Today there is a product called 3,4,5 - Trifluorobenzenesulfonyl Chloride, which is a raw material for chemical industry and has potential in many fields. Looking at this product, its future development is quite promising.
    In the process of scientific research, it may be the key to the development of new drugs. With its characteristics, it can make special drugs and treat difficult diseases in the world. On the industrial level, it can optimize material properties and make products more sophisticated.
    Although the current application of this product may have limitations, it will be able to expand its use over time with the advancement of science and technology and the depth of research and development. In the future, it may be widely used in high-end manufacturing, and the production industry will take off; or it may emerge in the field of green chemistry and contribute to environmental protection. I firmly believe that the future of this material will rise like the sun, shining brightly, with infinite possibilities and extraordinary achievements.
    Where to Buy 3,4,5-Trifluorobenzenesulfonyl Chloride in China?
    As a trusted 3,4,5-Trifluorobenzenesulfonyl Chloride manufacturer, we deliver: Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements. Technical Excellence: Precision-engineered solutions backed by R&D expertise, from formulation to end-to-end delivery. Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.
    Frequently Asked Questions

    As a leading 3,4,5-Trifluorobenzenesulfonyl Chloride supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

    What are the physical properties of 3,4,5-trifluorobenzenesulfonyl chloride?
    3,4,5-Trihydroxybenzaldehyde oxime is a special compound. Its physical properties are as follows:
    This compound is at room temperature and pressure, or in a solid state. Looking at its color, or in the form of white to light yellow powder, the appearance of this color is related to the distribution of electron clouds within its molecular structure and electron transitions. The powder is fine in texture and has a slightly greasy feel to the touch.
    When it comes to odor, or has a slight special smell, the smell is not pungent and unpleasant, but is caused by volatile substances produced by the interaction between various atoms in its molecular structure.
    As for its solubility, it may show a certain solubility in organic solvents, such as ethanol, acetone, etc. Ethanol, as a common organic solvent, can be combined with 3,4,5-trihydroxybenzaldehyde oxime molecules by hydrogen bonding and other interaction forces, so that the compound can be dissolved in ethanol to a certain extent. In water, due to the difference in the force between the water molecule and the compound molecule, its solubility is poor. Although there are hydroxyl groups in the compound molecule that can form hydrogen bonds with water, the existence of hydrophobic parts such as benzene rings limits its solubility in water.
    Its melting point is also one of the important physical properties. After determination, its melting point may be in a specific temperature range, and the value of this melting point depends on the strength of the intermolecular force. Intermolecular hydrogen bonds and van der Waals forces together determine that a certain amount of heat is required to disintegrate the lattice structure and transform the substance from solid to liquid.
    In summary, the physical properties of 3,4,5-trihydroxybenzaldehyde oxime are determined by their molecular structure, and these properties play a key role in various chemical reactions and practical applications.
    What are the chemical properties of 3,4,5-trifluorobenzenesulfonyl chloride?
    3,4,5-Trihydroxybenzaldehyde is an organic compound. It has the following chemical properties:
    1. ** Acidic **: The hydrogen in the phenolic hydroxyl group can be partially ionized and is weakly acidic. In water, the hydrogen of the phenolic hydroxyl group can be dissociated, making the solution acidic, but its acidity is weaker than that of common inorganic acids. In case of alkali, the phenolic hydroxyl group can react with the base to form phenolic salts and water. If it reacts with sodium hydroxide, 3,4,5-trihydroxybenzoate and water are formed, which is a typical property of phenolic compounds.
    2. ** Oxidation reaction **: The phenolic hydroxyl group is easily oxidized. In air, 3,4,5-trihydroxybenzaldehyde can be slowly oxidized by oxygen, and the color gradually darkens. When oxidized with strong oxidants such as potassium permanganate, phenolic hydroxyl groups can be further oxidized to quinones and other substances. Quinones have special colors and chemical activities, and this oxidation reaction is very important in organic synthesis and chemical analysis.
    3. ** Nucleophilic Substitution Reaction **: The aldehyde group is electrophilic and vulnerable to attack by nucleophilic reagents. Nucleophilic reagents such as alcohols can undergo nucleophilic addition reactions with aldehyde groups to generate hemiacetal, acetal and other products. Under appropriate conditions, the aldehyde group of 3,4,5-trihydroxybenzaldehyde can react with alcohol to form an acetal structure. This reaction is often used to protect aldehyde groups in organic synthesis.
    4. ** Condensation reaction **: The aldehyde group can undergo condensation reaction with compounds containing active hydrogen. For example, with aldol and ketone with α-hydrogen, the condensation reaction of hydroxyaldehyde can occur under alkali catalysis to generate β-hydroxyaldehyde or β-hydroxyketone. After dehydration, α, β-unsaturated aldehyde or ketone can be obtained. 3,4,5-trihydroxybenzaldehyde condensation reaction with suitable aldol and ketone can construct organic compounds with more complex structures, which are widely used in the field of organic synthesis.
    5. ** Color reaction **: Phenolic hydroxyl groups can undergo color reaction with ferric chloride solution. When 3,4,5-trihydroxybenzaldehyde meets ferric chloride solution, it can form a complex with a specific color, usually purple or blue. This reaction is often used to test the presence of phenolic hydroxyl groups and is commonly used in chemical analysis and identification of phenolic compounds.
    What are the common synthesis methods of 3,4,5-trifluorobenzenesulfonyl chloride?
    The common synthesis methods of 3,4,5-trifluorobenzoic anhydride are as follows:
    First, 3,4,5-trifluorobenzoic acid is used as the starting material to react with acetic anhydride. In this reaction, 3,4,5-trifluorobenzoic acid and acetic anhydride undergo acyl exchange reaction under heating conditions. The principle is that the acyl group activity of acetic anhydride is high, which can promote the dehydration of carboxyl groups in 3,4,5-trifluorobenzoic acid to form acid anhydride. The reaction process needs to be controlled by temperature. Generally, it is heated to an appropriate temperature range and maintained for a certain period of time to achieve a higher yield. After the reaction, the purified 3,4,5-trifluorobenzoic anhydride can be obtained through distillation, recrystallization and other purification steps.
    Second, 3,4,5-trifluorobenzoic acid is used to react with phosphorus oxychloride. Phosphorus oxychloride is a strong dehydrating agent, which can promote the intermolecular dehydration of 3,4,5-trifluorobenzoic acid to form anhydrides. This reaction is usually carried out in suitable organic solvents, such as dichloromethane. During the reaction, phosphorus oxychloride is slowly added dropwise to a solution containing 3,4,5-trifluorobenzoic acid, and stirred at low temperature to control the reaction rate and prevent side reactions. When the reaction is complete, the target product can be obtained through a series of operations such as hydrolysis, extraction, drying and distillation.
    Third, 3,4,5-trifluorobenzoyl chloride is used to react with anhydrous sodium carbonate. First, 3,4,5-trifluorobenzoyl chloride is prepared from 3,4,5-trifluorobenzoic acid, and then it interacts with anhydrous sodium carbonate. The reaction of 3,4,5-trifluorobenzoyl chloride with anhydrous sodium carbonate in an appropriate solvent, the carbonate ion promotes the condensation of benzoyl chloride molecules to form an acid anhydride. After the reaction is completed, after separation and purification, 3,4,5-trifluorobenzoic anhydride can be obtained.
    The above methods have advantages and disadvantages. In the actual synthesis, it is necessary to comprehensively consider the availability of raw materials, cost, yield and purity requirements, and choose the appropriate method.
    What are the main applications of 3,4,5-trifluorobenzenesulfonyl chloride?
    3,4,5-Trihydroxybenzaldehyde sulfonic acid is mainly used in many fields. In the field of medicine, it is a key intermediate for the preparation of specific drugs. The hydroxyl and aldehyde groups contained in this substance can be combined with other compounds through chemical reactions to synthesize drugs with special curative effects. For example, in the synthesis process of some antibacterial drugs, it can be used as a starting material to build the core structure of the drug through a series of chemical transformations, laying the foundation for the endowment of antibacterial activity.
    In the chemical industry, 3,4,5-trihydroxybenzaldehyde sulfonic acid also plays an important role. Because of its unique chemical structure and properties, it can act as an excellent catalyst or additive. In the synthesis process of polymer materials, adding an appropriate amount of this substance can effectively regulate the reaction rate and product properties, and improve the quality and performance of the material. Like in the synthesis of polyester, it may participate in the reaction, optimize the molecular structure of polyester, and enhance the stability and mechanical properties of polyester.
    In the field of materials science, this substance can be used to prepare functional materials. Its special functional groups can interact with other materials to give new functions to the material. For example, when preparing materials with adsorption properties, 3,4,5-trihydroxybenzaldehyde sulfonic acid can be used as an active check point to enhance the adsorption capacity of the material to specific substances, and play an important role in wastewater treatment, gas purification, etc.
    In summary, 3,4,5-trihydroxybenzaldehyde sulfonic acid has shown important application value in many fields such as medicine, chemical industry, and materials science due to its unique chemical structure and properties, and has promoted technological progress and development in various fields.
    What are the precautions for storing and transporting 3,4,5-trifluorobenzenesulfonyl chloride?
    3,4,5-Trifluorobenzoyl chloride is an important chemical substance. When storing and transporting, many matters must be taken into account.
    When storing, the first environment. When placed in a cool, dry and well-ventilated place, do not approach fire or heat sources. Cover because of its flammability, in case of heat or open flame, it may be dangerous. The temperature of the warehouse should be controlled within a specific range to prevent its chemical properties from changing due to excessive temperature. And it must be kept away from oxidants, alkalis and other substances. Because of its high chemical activity, contact with them can easily cause chemical reactions, damage its quality, or even be dangerous.
    Furthermore, storage containers are also crucial. Containers of suitable materials, such as corrosion-resistant metal or special plastic containers, must be selected to ensure their tightness and prevent leakage. Containers must be checked regularly to see if they are damaged or leaking. If so, they must be disposed of in time.
    When transporting, it is necessary to follow relevant regulations and standards. Vehicles must have good protective measures to ensure that they are not damaged by vibration and collision during transportation. And transport personnel should be professionally trained to be familiar with the characteristics of this substance and emergency treatment methods. During transportation, they must also pay attention to weather conditions. In case of severe weather such as high temperature and rainstorm, they should be properly dealt with, choose a safe place to temporarily shelter, and wait for the weather to be suitable before transporting.
    Also, whether it is storage or transportation, a complete emergency treatment plan should be in place. In the event of an accident such as a leak, it should be able to respond quickly and take effective measures, such as evacuating personnel, sealing the scene, and using appropriate materials to absorb the leak, etc., to minimize the harm. In this way, the safety of 3,4,5-trifluorobenzoyl chloride during storage and transportation is guaranteed.