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(2R,3S)-2-[(1R)-L-[3,5-Bis(Trifluoromethyl)Phenyl]Ethoxy]-3-(4-Fluorophenyl)-Morpholine, 4-Methylbenzenesulfonate

(2R,3S)-2-[(1R)-L-[3,5-Bis(Trifluoromethyl)Phenyl]Ethoxy]-3-(4-Fluorophenyl)-Morpholine, 4-Methylbenzenesulfonate

Hongda Chemical

Specifications

HS Code

343867

Chemical Name (2R,3S)-2-[(1R)-L-[3,5-Bis(trifluoromethyl)phenyl]ethoxy]-3-(4-fluorophenyl)morpholine, 4-methylbenzenesulfonate

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Packing & Storage
Packing 100g of (2R,3S)-2-[(1R)-l-[3,5 -bis(trifluoromethyl)phenyl]ethoxy]-3-(4 -fluorophenyl)morpholine, 4 -methylbenzenesulfonate in sealed container.
Storage Store (2R,3S)-2-[(1R)-1-[3,5 - bis(trifluoromethyl)phenyl]ethoxy]-3-(4 - fluorophenyl)morpholine, 4 - methylbenzenesulfonate in a cool, dry place away from direct sunlight and heat sources. Keep it in a tightly sealed container to prevent moisture absorption and potential reaction with air components. Ensure storage area is well - ventilated and separated from incompatible substances.
Shipping Ship (2R,3S)-2-[(1R)-1-[3,5 - bis(trifluoromethyl)phenyl]ethoxy]-3-(4 - fluorophenyl)morpholine, 4 - methylbenzenesulfonate in suitable, chemically - resistant packaging. Ensure compliance with regulations for chemical shipping.
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(2R,3S)-2-[(1R)-L-[3,5-Bis(Trifluoromethyl)Phenyl]Ethoxy]-3-(4-Fluorophenyl)-Morpholine, 4-Methylbenzenesulfonate (2R,3S)-2-[(1R)-L-[3,5-Bis(Trifluoromethyl)Phenyl]Ethoxy]-3-(4-Fluorophenyl)-Morpholine, 4-Methylbenzenesulfonate
General Information
Historical Development
(2R, 3S) -2- [ (1R) -L- [3,5-Bis (trifluoromethyl) phenyl] ethoxy] -3- (4-fluorophenyl) morpholine-4-methylbenzene sulfonate The historical development of this compound has its roots. In the past, all kinds of chemists spared no effort in the exploration of compounds. At the beginning, the study of such structures was still ignorant and only scratched the surface. After years of pondering, the skills improved day by day, and the analysis was subtle. Gradually understand its molecular structure and gain insight into the relationship between atoms. With the passage of time, the synthesis method has also changed from simple to complex, from coarse to fine. Many ingenious methods have emerged, making the preparation of this compound more smooth and the purity has also been improved. In the past, it was unattainable, but now it can be reached. This is the condensation of the efforts of researchers of all generations, so that this product can show its unique brilliance in the field of chemistry.
Product Overview
There is now a substance named\ ((2R, 3S) -2- [ (1R) -L- [3,5-bis (trifluoromethyl) phenyl] ethoxy] -3- (4-fluorophenyl) morpholine, 4-methylbenzene sulfonate\). This substance has a unique spatial configuration due to its delicate structure. The specific chirality of the 2nd and 3rd positions, as well as the various special groups connected, make it unique in the field of chemistry. 3,5-bis (trifluoromethyl) phenyl and 4-fluorophenyl give it special electronic effects and spatial steric resistance, while the morpholine ring structure adds specific chemical activity and reaction check points. 4-Methylbenzene sulfonate can also affect its physical and chemical properties, such as solubility and stability. Such a unique structure may show unique value in many fields such as drug development and materials science, and it is worth further exploring its properties and applications.
Physical & Chemical Properties
(2R, 3S) 2- [ (1R) -L- [3,5-Bis (trifluoromethyl) phenyl] ethoxy] -3- (4-fluorophenyl) morpholine-4-methylbenzene sulfonate, the physical and chemical properties of this compound are the key to our research. Its physical properties, or its crystalline state, whether the color is pure or not, depends on the purity geometry. Its melting point and boiling point values, under specific conditions, demonstrate its stability and volatility.
In terms of chemical properties, the functional group of this compound determines its reactivity. The benzene ring structure gives it aromatic properties, which can be used in organic reactions, or can participate in reactions such as electrophilic substitution. The presence of morpholine ring affects the spatial configuration of molecules and the distribution of electron clouds. Trifluoromethyl, fluorophenyl and methyl benzenesulfonic acid groups all have unique effects on their chemical behavior, or promote specific reactions or inhibit other reaction pathways. All of these need to be further explored to clarify the full picture of their physical and chemical properties and lay the foundation for subsequent research and application.
Technical Specifications & Labeling
There is now a product with the name (2R, 3S) - 2 - [ (1R) - L - [3,5 - bis (trifluoromethyl) phenyl] ethoxy] - 3 - (4 - fluorophenyl) morpholine, 4 - methylbenzene sulfonate. To clarify its technical specifications and identification (product parameters), it is necessary to study its manufacturing process in detail.
Its preparation also requires precise methods. The material ratio must be suitable, and the reaction conditions must also be carefully observed. The control of temperature is related to the quality of the product. If it is too high or too low, it can lead to deviation. The reaction time is also the key. If it is too short, it will not be fully responded, too long or miscellaneous.
In terms of identification, clarity and accuracy are essential. Product parameters, such as purity and characteristics, should be detailed so that viewers can see at a glance, so as to distinguish their advantages and disadvantages and know their suitability. In this way, the technical specifications and identification of this product can be obtained, which is beneficial for research and use.
Preparation Method
The raw materials of (2R, 3S) -2- [ (1R) -L- [3,5-bis (trifluoromethyl) phenyl] ethoxy] -3- (4-fluorophenyl) morpholine, 4-methylbenzene sulfonate are the key to the production process, reaction steps and catalytic mechanism.
The raw materials for making this drug need to be carefully selected, and the purity and characteristics are strictly required. The production process is such as tenon-mortise fit, and each step affects the quality of the finished product.
The reaction steps must be carried out in sequence, and the temperature, time and material ratio must be precisely controlled. First, the specific raw materials are mixed and stirred at a suitable temperature to promote the reaction. After the reaction reaches a certain level, follow-up operations are carried out.
The catalytic mechanism cannot be ignored. Selecting the right catalyst can accelerate the reaction, improve the yield and purity. With exquisite catalysis, the reaction is like a boat on the water, and this product is efficiently obtained, which contributes to medical research and can benefit patients.
Chemical Reactions & Modifications
There is now a thing named (2R, 3S) -2- [ (1R) -L- [3,5 -bis (trifluoromethyl) phenyl] ethoxy] -3- (4 -fluorophenyl) morpholine, 4 -methylbenzene sulfonate. In the field of chemistry, we observe its chemical reaction and modification.
Look at this compound, its structure is unique, and each group interacts to form its own characteristics. The beauty of its reaction lies in the change of electron clouds between atoms and groups, and the disconnection of bonds. Either nucleophilic or electrophilic, depending on its structure and external conditions.
As for modification, it is to change its physical and chemical properties to suit different purposes. Or increase its stability, or change its solubility, or adjust its activity. This all depends on a deep understanding of its reaction mechanism, choosing appropriate methods, such as substitution, addition, elimination and other reactions, in order to achieve the purpose of modification, and to contribute to the development of chemistry and practical products.
Synonyms & Product Names
There is now a substance with the name (2R, 3S) - 2 - [ (1R) - L - [3,5 - bis (trifluoromethyl) phenyl] ethoxy] - 3 - (4 - fluorophenyl) morpholine, 4 - methylbenzene sulfonate. In the field of chemistry, it is the key to research. The synonym of this substance and the trade name also have important meanings. Synonyms refer to those whose names are different but refer to the same substance; trade names are related to market labels. In the course of my chemical research, clarifying the synonyms and trade names of this object is like holding a lamp to explore the path, which can help us accurately identify and use it, and proceed unimpeded in our research without confusion, thus promoting the process of research and exploring deeper chemical mysteries.
Safety & Operational Standards
(2R, 3S) -2- [ (1R) -L- [3,5-Bis (trifluoromethyl) phenyl] ethoxy] -3- (4-fluorophenyl) morpholine, 4-methylbenzene sulfonate is a chemical we have studied. Its safety and operating standards are of paramount importance, and it is crucial to the success or failure of the experiment and the safety of personnel.
In the operating place, it is essential to maintain air circulation. Because some components of the chemical may be volatile, accumulate in closed spaces, or pose a risk of poisoning. Therefore, ventilation equipment should be installed to ensure fresh air.
Furthermore, operators need professional protective equipment. Protective gloves must be worn to prevent skin contact. This chemical may be irritating and corrosive to the skin. If it is contaminated, rinse with plenty of water quickly and seek medical attention. Also wear goggles, the eyes are fragile, and chemicals splash in, or cause serious damage.
When operating, strictly follow the procedures. Accurate weighing and proportioning are related to the purity of the product and the reaction effect. The experimental instrument must be clean and dry to avoid the influence of impurities. The reaction temperature, time and other conditions should also be precisely controlled and must not be changed without authorization.
Store the chemical in a cool, dry and ventilated place. Keep away from fire and heat sources because it may be flammable. Different ingredients should be stored in categories to prevent mutual reaction. And clearly marked, indicating the name, nature, harm and other information should be posted.
Disposal should also not be ignored. It should not be dumped at will. It should be collected in accordance with relevant regulations and handed over to professional institutions for treatment to avoid polluting the environment.
In short, the safety and operation specifications of (2R, 3S) 2- [ (1R) -L- [3,5-bis (trifluoromethyl) phenyl] ethoxy] -3- (4-fluorophenyl) morpholine, 4-methylbenzenesulfonate need to be kept in mind and practiced carefully to ensure the safety and smoothness of the experiment.
Application Area
(2R, 3S) - 2 - [ (1R) - L - [3,5 - bis (trifluoromethyl) phenyl] ethoxy] - 3 - (4 - fluorophenyl) morpholine, 4 - methylbenzene sulfonate This substance is widely used in chemical research today. Its application field involves a corner of medical drug research and development. With the understanding of pharmacy, or with its special molecular structure, it can explore the preparation of new drugs, hoping to be helpful in the treatment of diseases. For example, the development of drugs for treating certain kinds of difficult and miscellaneous diseases, or based on this, through exquisite synthesis, the drug has better efficacy and safety. And in the field of chemical synthesis, it is also useful. It can be a key intermediate for the synthesis of other substances. With its unique properties, it can guide the reaction to the desired path to obtain materials with specific properties, and it also has a role in promoting the progress of materials science.
Research & Development
I have studied (2R, 3S) -2- [ (1R) -L- [3,5-bis (trifluoromethyl) phenyl] ethoxy] -3- (4-fluorophenyl) morpholine, 4-methylbenzenesulfonate for a long time. This substance has unique characteristics and has great potential in various fields.
The initial research, analyzing its structure, gaining insight into the delicate molecular structure, lays the foundation for subsequent exploration. Then study its synthesis path, and strive for an efficient and pure method through repeated attempts and optimization. In the experiment, the effects of reaction conditions, such as temperature and catalyst dosage, on the product were carefully observed.
Through unremitting efforts, the synthesis process has been improved day by day, and the purity and yield of the product have been improved. However, there are still challenges in the road of research, such as the control of side reactions. In the future, we hope to further optimize the process, expand the application scope, and realize the leap from laboratory to actual production. We will promote the wide application of this substance in various fields and contribute to scientific research and industrial development.
Toxicity Research
The toxicity of (2R, 3S) -2- [ (1R) -L- [3,5-bis (trifluoromethyl) phenyl] ethoxy] -3- (4-fluorophenyl) morpholine, 4-methylbenzene sulfonate is studied today. It has a unique structure and contains trifluoromethyl, fluorophenyl and other groups. Toxicity studies are related to the safety of living beings, such as entering the human body, or through breathing, ingestion, skin contact and other routes. First observe its acute toxicity, take animals as tests, and observe their short-term reactions, such as behavioral, physical signs, and organ changes. Then explore chronic toxicity, long-term low-dose exposure, and analyze the effects on body function and histopathology. And it is necessary to study its mutagenicity to see if it leads to changes in genes and chromosomes to break genotoxicity. The road to toxicity research is long, and it is related to the survival of all things. We should be cautious and explore unremitting for the well-being of all living beings.
Future Prospects
There is a compound named (2R, 3S) -2- [ (1R) -L- [3,5-bis (trifluoromethyl) phenyl] ethoxy] -3- (4-fluorophenyl) morpholine, 4-methylbenzene sulfonate. As researchers of chemicals, we look forward to the future of this compound with great expectations.
This compound has a unique structure and may shine in the field of medicine. In the future, it may be possible to use its characteristics to develop new agents to treat intractable diseases and relieve the suffering of patients. It may become a key material in the process of organic synthesis and lead to the innovation of chemical technology.
Although the road ahead is long, our researchers must have a determined heart and persevere. With unremitting efforts, we hope to maximize the potential of this compound, contribute to human well-being and scientific progress, and create a brilliant future.
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Frequently Asked Questions

As a leading (2R,3S)-2-[(1R)-L-[3,5-Bis(Trifluoromethyl)Phenyl]Ethoxy]-3-(4-Fluorophenyl)-Morpholine, 4-Methylbenzenesulfonate supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

What is the chemical structure of (2R, 3S) -2- [ (1R) -L- [3,5-bis (trifluoromethyl) phenyl] ethoxy] -3- (4-fluorophenyl) morpholine, 4-methylbenzenesulfonate?
(The structure of this compound is quite complex, let me go through it in detail.) This compound is named after it ((2R, 3S) -2- [ (1R) -L- [3,5-bis (trifluoromethyl) phenyl] ethoxy] -3- (4-fluorophenyl) butene, 4-methylbenzenesulfonate), and its structure can be gradually analyzed.
First, the main chain is a butene structure containing double bonds, with specific substituents at the 2nd and 3rd positions, respectively, and the configurations are R and S. The substituent at the 2nd position is ethoxy, and the ethoxy group is connected with a structure, namely (1R) -L- [3,5-bis (trifluoromethyl) phenyl]. This benzene is based on trifluoromethyl at the 3rd and 5th positions, and the structure has a specific R configuration. The 3rd position is connected with 4-fluorophenyl. The 4th position of the butene structure is connected with 4-methylbenzene sulfonate group.
In this way, the chemical structure of this compound can be outlined by connecting the structure of each part according to the position and configuration shown in the name. In this structure, each atom and group are connected to each other to form a specific spatial arrangement to meet its stereochemical requirements and overall structural characteristics.
What are the physical properties of (2R, 3S) -2- [ (1R) -L- [3,5-bis (trifluoromethyl) phenyl] ethoxy] -3- (4-fluorophenyl) morpholine, 4-methylbenzene sulfonate?
(This is an extremely complex organic compound, which is (2R, 3S) -2- [ (1R) -L - [3,5-bis (trifluoromethyl) phenyl] ethoxy] -3- (4-fluorophenyl) pentene, 4-methylbenzenesulfonate. Its physical properties are quite important and are related to many applications of this compound.)
The physical properties of this compound, the first is the melting point. The melting point is the temperature at which a substance changes from a solid state to a liquid state. However, due to the extremely complex structure involved, the spatial resistance and intermolecular forces are intertwined, so the determination of its melting point requires fine operation. Or because of the high electronegativity of fluorine atoms, coupled with the influence of the benzene ring conjugation system, the intermolecular force is enhanced, and the melting point may be in a higher range. However, the exact value needs to be accurately determined by experiments.
Second words boiling point. The boiling point is restricted by the intermolecular force and the relative molecular weight. This compound contains many functional groups and a large benzene ring structure, and has a relatively large molecular weight. In addition to van der Waals force, there may be special interactions such as hydrogen bonds between molecules. Therefore, its boiling point may be considerable. Due to the complex structure, more energy is required for molecular separation, but the specific boiling point also depends on experimental investigation.
In terms of solubility, because it contains hydrophobic phenyl groups and trifluoromethyl groups, it may have good solubility in non-polar organic solvents such as toluene and dichloromethane. In polar solvents such as water, the solubility may be poor due to the relatively small proportion of polar functional groups in the structure. However, factors such as solvent polarity and temperature will also affect the solubility.
The density is related to the mass per unit volume of the substance. In view of the complex atomic composition and spatial arrangement of this compound, the density may be different from that of common organic compounds. Its exact density needs to be determined by precise experimental instruments, or due to the presence of heavy atoms such as fluorine, the density increases.
In addition, the refractive index of this compound is also an important physical property. The refractive index is related to the molecular structure and the distribution of electron clouds. The complex benzene ring structure and the electronic effect of fluorine atoms may give the refractive index a unique value, which is of great significance for its optical applications. However, the specific value still needs to be obtained experimentally.
What is the synthesis method of (2R, 3S) -2- [ (1R) -L- [3,5-bis (trifluoromethyl) phenyl] ethoxy] -3- (4-fluorophenyl) morpholine, 4-methylbenzene sulfonate?
To prepare (2R, 3S) - 2 - [ (1R) - L - [3,5 - bis (trifluoromethyl) phenyl] ethoxy] - 3 - (4 - fluorophenyl) pentadiene, 4 - methylbenzoic anhydride, the method is as follows:
First take an appropriate amount of (1R) - L - [3,5 - bis (trifluoromethyl) phenyl] ethanol, in a suitable reaction vessel, add an appropriate amount of base, such as potassium carbonate, etc., to activate the alcohol hydroxyl group. Then slowly add the halogenate containing 2-halogenated ethyl-3- (4-fluorophenyl) pentadiene structure, control the reaction temperature and time, and make the two undergo nucleophilic substitution reaction to obtain (2R, 3S) -2- [ (1R) -L- [3,5-bis (trifluoromethyl) phenyl] ethoxy] -3- (4-fluorophenyl) pentadiene precursor.
Then, the obtained precursor is appropriately purified, and column chromatography can be used to remove impurities.
As for the preparation of 4-methylbenzoic anhydride, take 4-methylbenzoic acid, add an appropriate amount of dehydrating agent, such as the mixture of acetic anhydride and concentrated sulfuric acid, heat and stir to promote the dehydration reaction to generate 4-methylbenzoic anhydride. After the reaction is completed, the pure 4-methylbenzoic anhydride can be obtained through cooling, liquid separation, washing and other steps.
Thus, according to the above steps, the desired (2R, 3S) - 2 - [ (1R) - L - [3,5 - bis (trifluoromethyl) phenyl] ethoxy] - 3 - (4 - fluorophenyl) pentadiene and 4 - methylbenzoic anhydride can be prepared.
What are the uses of (2R, 3S) -2- [ (1R) -L- [3,5-bis (trifluoromethyl) phenyl] ethoxy] -3- (4-fluorophenyl) morpholine, 4-methylbenzene sulfonate?
(This is a very complex organic compound naming, in order to clarify its use, and let me explain it in detail.) The path involved in this compound is the first in the field of medicine. Because of its unique structure or specific biological activity, it can be used as a key intermediate for drug research and development. In the path of drug synthesis, based on this, through delicate chemical reactions, it may be able to produce new drugs with excellent efficacy and strong targeting, providing assistance for the treatment of difficult diseases.
Furthermore, in the field of organic synthetic chemistry, it is also of great significance. With its complex and unique structure, chemists can use it to explore new synthetic methods and strategies. By modifying and modifying it, the mechanism of organic reactions can be deeply studied, the boundaries of organic synthesis can be expanded, and the foundation for the creation of more novel and complex organic compounds can be laid.
In addition, in the field of materials science, if some of its properties are properly regulated, it may be applied to the creation of new functional materials. If it has special optical and electrical properties, it is expected to be used to manufacture high-performance optoelectronic materials and promote technological innovation in related fields.
In short, although the structure of this compound is complex and difficult to distinguish, it has unlimited possibilities in many fields such as medicine, chemistry, and materials. It is waiting for scientific researchers to deeply explore and tap its hidden value, so as to contribute to human well-being.
What are the market prospects for (2R, 3S) -2- [ (1R) -L- [3,5-bis (trifluoromethyl) phenyl] ethoxy] -3- (4-fluorophenyl) morpholine, 4-methylbenzene sulfonate?
Guanfu (2R, 3S) -2- [ (1R) -L- [3,5-bis (trifluoromethyl) phenyl] ethoxy] -3- (4-fluorophenyl) butene, 4-methylbenzenesulfonate. The market prospect of this product is quite promising.
In today's world, the pharmaceutical and chemical industry is booming, and the demand for fine chemicals is increasing day by day. This compound has a unique structure and may be of extraordinary use in pharmaceutical research and development. It has a complex spatial configuration or can accurately fit with specific biological targets. When new drugs are created, it is a key intermediate, such as the development of targeted anti-cancer drugs and drugs for the treatment of nervous system diseases.
Furthermore, in the field of materials science, it may have potential value. Due to its fluorine content and specific phenyl structure, it may endow materials with unique physical and chemical properties, such as improving material stability, corrosion resistance, and even optical properties, so it may emerge when high-performance materials are prepared.
However, its market prospects also pose challenges. The synthesis process may be difficult due to complex structures, and cost control and yield increase are all priorities. And the market competition is fierce. If similar substitutes or exist, if they want to gain a place in the market, they must work quickly on technological innovation and cost optimization.
In summary, (2R, 3S) -2- [ (1R) -L- [3,5-Bis (trifluoromethyl) phenyl] ethoxy] -3- (4-fluorophenyl) butene, 4-methylbenzenesulfonate Although promising, it also needs to face challenges in order to shine in the market.