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2-Trifluoromethylnitrobenzene

2-Trifluoromethylnitrobenzene

Hongda Chemical

Specifications

HS Code

522480

Chemical Formula C7H4F3NO2
Molecular Weight 191.11
Appearance Colorless to light yellow liquid
Boiling Point 207 - 208 °C
Melting Point 10 - 11 °C
Density 1.439 g/cm³
Flash Point 92 °C
Solubility In Water Insoluble
Vapor Pressure Low
Odor Characteristic aromatic odor

As an accredited 2-Trifluoromethylnitrobenzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

Packing & Storage
Packing 100 - gram bottles of 2 - trifluoromethylnitrobenzene, well - sealed for chemical storage.
Storage 2 - Trifluoromethylnitrobenzene should be stored in a cool, dry, and well - ventilated area, away from heat sources and open flames. It should be stored in a tightly - sealed container to prevent leakage. Keep it separate from oxidizing agents, reducing agents, and combustible materials. Storage areas should be equipped with appropriate spill - containment facilities.
Shipping 2 - trifluoromethylnitrobenzene is shipped in sealed, corrosion - resistant containers. Due to its chemical nature, it requires careful handling. Shipments follow strict regulations to ensure safety during transport.
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2-Trifluoromethylnitrobenzene 2-Trifluoromethylnitrobenzene
General Information
Historical Development
2-Trifluoromethyl nitrobenzene is also an organic compound. The beginning of its research was curiosity and knowledge, hoping to explore the wonders of physical properties. In the past, Zhu Xian Da thought hard, with simple tools and tenacity, began to glimpse the secret.
At the beginning, the synthesis method was difficult and abnormal, the yield was low and impurities were abundant. However, everyone was reluctant to give up, and it was easier to follow and improve the steps. Gradually, the new method appeared, and the yield gradually increased.
Over the years, more and more researchers have come to understand it. In the reaction mechanism, it is clear in detail; in the field of application, it is widely expanded. From medical chemistry to materials science, it can be seen. From this perspective, the evolution of 2-trifluoromethyl nitrobenzene is the blood coagulation of all wise people, which adds to the progress of chemistry. The future path will definitely become more and more brilliant.
Product Overview
Product Overview of 2-Trifluoromethylnitrobenzene
2-Trifluoromethylnitrobenzene is a crucial compound in the field of organic synthesis. Its appearance is colorless to light yellow liquid, with a special odor, and it is widely used in many fields of chemical industry.
The preparation of this product often uses specific aromatic hydrocarbons as the starting material and is carefully synthesized by multi-step reaction. The reaction conditions need to be precisely controlled to obtain high yield and purity.
In the field of pharmaceutical synthesis, 2-trifluoromethylnitrobenzene is a key intermediate. It can be converted in a series to produce a variety of specific drugs, which contribute greatly to human health. In the field of materials science, it can participate in the preparation of high-performance polymer materials, giving them excellent properties such as corrosion resistance and heat resistance.
However, when using 2-trifluoromethyl nitrobenzene, it is necessary to pay attention to safety. Because of its certain toxicity and irritation, strict safety procedures must be followed during operation, and protective measures must be taken to ensure the safety of personnel and the environment is not polluted. In this way, the advantages of this product can be better utilized to promote the vigorous development of chemical-related industries.
Physical & Chemical Properties
2, -Trifluoromethyl nitrobenzene, an organic compound. Its physical and chemical properties are worth studying. Looking at its physical properties, at room temperature, it is a colorless liquid with a special odor. Its boiling point is moderate, which is conducive to separation and purification. As for chemical properties, due to the presence of nitro groups and trifluoromethyl groups, the activities are different. Nitro groups are highly oxidizing and can participate in many nucleophilic substitution reactions. Trifluoromethyl, on the other hand, has strong electron absorption properties, which affect the electron cloud distribution of molecules, causing the electron cloud density of the benzene ring to decrease and the reaction activity to change. In the process of synthesis, it is often a key intermediate, and through various reactions, a variety of high-value-added products can be prepared. From this point of view, 2-trifluoromethyl nitrobenzene plays an important role in the field of organic synthesis, and the study of its physicochemical properties can lay the foundation for its wider application.
Technical Specifications & Labeling
2-Trifluoromethyl nitrobenzene is also a chemical product. Its technical specifications and identification (product parameters) are related to the quality and use of this substance.
To make this 2-trifluoromethyl nitrobenzene, specific regulations must be followed. The ratio of raw materials, the temperature and time of the reaction are all fixed. If the raw material is pure, it must meet the standard, otherwise it will affect the product. If the reaction temperature is too high, the side should be produced, and if it is too low, the speed will be slow.
In terms of identification, the product parameters must be specified. The geometry and purity of the impurities contained should be detailed. In this way, the user can judge whether it is suitable or not according to the parameters. Proper technical specifications and identification (product parameters) can ensure the superiority of 2-trifluoromethyl nitrobenzene for use in various industries and promote its progress.
Preparation Method
This product is made of 2-Trifluoromethylnitrobenzene, first take the raw materials. Fluoride and nitrobenzene are used as the basis, and the two are matched to react.
The preparation method first places the raw materials in a special reactor according to a certain amount ratio. The kettle needs to be temperature and pressure resistant to prevent the reaction from escaping. Then adjust the temperature in the kettle to gradually rise to a suitable degree, about [X] degrees Celsius, and control the pressure at [X] Pascal.
When reacting, stir to allow the raw materials to be fully mixed to accelerate the reaction process. After this reaction has passed for several times, until the reaction is complete, the state of the product, whether liquid or solid, varies according to conditions.
After the reaction is completed, the product is taken out from the kettle. After separation and purification, its impurities are removed to obtain 2-Trifluoromethylnitrobenzene of purity. In this process, filtration, distillation, etc. are used to make the product reach the required purity. In this way, the refined 2-Trifluoromethylnitrobenzene is obtained to meet the needs of all parties.
Chemical Reactions & Modifications
2-Trifluoromethyl nitrobenzene is also an organic compound. In the field of chemical synthesis, its reaction and modification are quite important to scholars.
To prepare this compound, a specific reaction path is often used. For example, after halogenation, nitrification and other steps, the organic reagents are complemented to make the reaction proceed in sequence. However, in the reaction, the control of conditions is the key. Temperature, pressure, and the amount of catalyst can all affect the rate of the reaction and the purity of the product.
And there are various ways to modify it. New groups can be introduced by means of the conversion of functional groups to change their chemical properties. If you want to increase its hydrophilicity, you can introduce hydroxyl groups and the like; if you want it to have special reactivity, you can add functional groups containing nitrogen and phosphorus. All of this depends on chemists studying the mechanism in detail and adjusting the parameters carefully, in order to obtain ideal products for use in chemical, pharmaceutical and other industries.
Synonyms & Product Names
"Same noun and trade name of" 2-trifluoromethyl nitrobenzene "
Fu" 2-trifluoromethyl nitrobenzene "is an important substance in the chemical industry. In the industry, the same noun and trade name have their own names. The chemical name of this compound is established, but it has practical application, or it has different names due to different manufacturers and regions.
may have a separate product name due to its characteristics, which highlights its uniqueness. Although the names are different, the actual quality is the same. A chemist should clearly refer to the same thing, and should not be confused by the different names. Although the same noun and the trade name are different, its chemical nature and use have not changed greatly.
In the path of chemical exploration, it is essential to accurately grasp this thing, no matter what it is called, to be able to understand its rationale and use it.
Safety & Operational Standards
"Code of Safety and Operation of Difluoromethyl Nitrobenzene"
Difluoromethyl nitrobenzene is also a chemical product. Its characteristics are different, and it is related to safe operation. Do not be careless.
At the beginning of preparation, all utensils must be clean and dry to prevent impurities from interfering with their reactions and causing accidental changes. The raw materials used should be carefully selected to check their purity. If the quality is poor, the reaction will be difficult to control and may be dangerous.
When operating, it is appropriate to be in a well-ventilated place. This substance may be toxic and irritating. If it enters the lungs in the gas-depressed room, it will damage health. And the operator, in front of protective equipment, such as protective clothing, gloves, goggles, etc., do not let the skin and eyes contact it.
When heating, the heat must be stable. If the fire is hot, it may cause overreaction and cause the risk of bursting. Stirring should also be at a constant speed to make the reaction uniform and avoid local overheating.
When storing, it should be placed in a cool, dry and ventilated place. Keep away from fire and heat sources and avoid direct sunlight. Because of its explosive nature, if there is a slight carelessness, it will cause an instant disaster.
Disposal should not be ignored. Do not pour it into the ditch at will, and handle it properly in accordance with relevant regulations to avoid polluting the environment and harming life.
In short, the safety and operating standards of difluoromethylnitrobenzene are interlinked, which are related to personal safety and environmental well-being. Operators must abide by its regulations in order to avoid danger and ensure all things go smoothly.
Application Area
2-Trifluoromethyl nitrobenzene is also a chemical product. Its application field is quite wide. In the field of pharmaceutical synthesis, it can be used as a key intermediate to help create special drugs to treat various diseases. In the field of agrochemical, it can be the cornerstone of the synthesis of high-efficiency pesticides, protecting the village to control pests and increase the yield of crops. It is also used in materials science to assist in the research of new materials, making them specific, such as better weather resistance and wear resistance. Therefore, 2-trifluoromethyl nitrobenzene has great value in many practical fields, and can be used for the development of various industries. Its function in the world should not be underestimated.
Research & Development
The chemical industry is changing with each passing day, and new products are emerging one after another. In this sentence 2 - Trifluoromethylnitrobenzene this product, its research and development are quite important.
At the beginning, this compound was studied to explore its chemical properties. After repeated experiments, it was found that its structure is exquisite and its reaction is unique. Chemists have worked hard to observe its changes under different conditions, hoping to understand its laws.
As for development, its prospects are broad. In the field of materials, materials with special properties can be made to increase their stability and functionality. In medicine, it is also expected to become a key ingredient in new drugs, bringing new opportunities for the treatment of diseases.
The road to research is full of thorns. The method of synthesis needs to be more efficient and environmentally friendly; the exploration of nature still needs to be deepened. Scientists should persevere and move forward with determination, hoping to make the research and development of 2-Trifluoromethylnitrobenzene reach a high level and benefit the world.
Toxicity Research
"On the toxicity of 2-trifluoromethyl nitrobenzene"
Fu 2-trifluoromethyl nitrobenzene is also a chemical substance. For our generation of chemical researchers, the study of its toxicity is crucial.
The molecular structure of this substance is unique, containing trifluoromethyl and nitro groups. According to various experiments, it has a certain toxicity. In terms of biological effects, it may be able to damage the normal operation of cells. In small animal experiments, it was found that after exposure to this substance, some physiological functions of the body were abnormal.
And it is also potentially dangerous in the environment. If accidentally released, or dirty soil and water sources. Although it has its use in the chemical industry, the risk of toxicity should not be ignored. We should study its toxicity mechanism in depth and strive to find proper ways to reduce its harm, so as to achieve a balance between chemical development and safety.
Future Prospects
The future prospect concerns 2-trifluoromethyl nitrobenzene. In today's chemical research, this substance has shown extraordinary quality. Its unique structure, containing trifluoromethyl and nitro groups, has different properties, and is emerging in the field of materials and pharmaceutical research and development.
Looking at the future, in the field of materials, it is expected to use its characteristics to create new materials with better performance, or with excellent stability and weather resistance, which will contribute to the construction, aviation and other industries. In terms of medicine, based on it, in-depth research may lead to the development of new drugs with special effects to overcome difficult diseases and benefit the common people.
Although there may be thorns in the road ahead, science has advanced, and it is not afraid of obstacles. Our chemical researchers, with enthusiasm and diligence, hope to expand their potential with wisdom and sweat, develop a bright future for 2-trifluoromethyl nitrobenzene, and make immeasurable contributions to human well-being.
Where to Buy 2-Trifluoromethylnitrobenzene in China?
As a trusted 2-Trifluoromethylnitrobenzene manufacturer, we deliver: Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements. Technical Excellence: Precision-engineered solutions backed by R&D expertise, from formulation to end-to-end delivery. Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.
Frequently Asked Questions

As a leading 2-Trifluoromethylnitrobenzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

What are the main uses of 2-trifluoromethylnitrobenzene?
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First, it can be used to treat diseases. It is unique and has certain medicinal effects. According to many medical records, it has the ability to regulate and treat certain diseases. It can help regulate the flow of qi and blood in the body and relieve some discomfort caused by poor qi and blood. For diseases caused by dysfunction of the viscera, it can also play a certain role in improving, helping the viscera to restore its normal transportation ability, and returning the body to the balance of yin and yang.
Second, it is beneficial for health preservation. The ancients attached great importance to the way of health, 2-%E4%B8%89%E6%B0%9F%E7%94%B2%E5%9F%BA%E7%A1%9D%E5%9F%BA%E8%8B%AF%E7%9A%84%E characteristics, which can help nourish the body and keep fit. Taking it regularly can enhance the body's ability to resist external evil, just like building a protective barrier for the body. It can improve the integrity of the human body, fill the qi and blood, and be full of spirit, thereby delaying the process of aging, so that people can maintain a good mental and physical state.
Third, it is also useful in the field of alchemy and pharmaceuticals. Ancient alchemists deeply explored the characteristics of various types of drugs, 2-%E4%B8%89%E6%B0%9F%E7%94%B2%E5%9F%BA%E7%A1%9D%E5%9F%BA%E8%8B%AF%E7%9A%84 certain ingredients, which can interact with other drugs during alchemy, or change the texture of pills, or enhance the efficacy of pills. Its unique chemical properties provide the possibility to refine pills of good quality and strange effects, and occupy a certain position in the development of ancient alchemy and pharmaceuticals.
What are the physical properties of 2-trifluoromethylnitrobenzene?
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This medicine is hard and brittle, and it is easy to break when touched. The color is light yellow, and it looks like the first blooming of autumn chrysanthemum, with a light and elegant color. Smell it, it has a special smell, although it is not rich and pungent, it is different from other things, and it can be distinguished by smelling it. Its taste is slightly bitter, and the tip of the tongue has a slight astringent feeling, which does not dissipate for a long time.
In case of fire, it will burn. When burning, the flame is bright, accompanied by light smoke rising, burning, and the embers are white and delicate like powder. In water, it initially floats on the surface, gradually sinks, and the water color changes slightly, showing a yellowish shape, and a faint medicinal fragrance dissolves into the water. If it is decocted in hot soup, its effective ingredients gradually dissolve in the soup, making the soup turn dark yellow and the smell more intense.
Its density is slightly lighter than that of ordinary wood and stone, and when held in the hand, it has a light feeling, not as heavy as gold and stone. Although its texture is hard and brittle, it can be cut with a sharp blade, and it can also be crushed. The crumbs are fine and uniform.
Looking at its physical properties, they all have unique characteristics, which are very different from common things. When a doctor uses medicine, he should also observe its properties carefully, so as to make good use of it, in order to receive its effect and treat people's diseases.
Is the chemical property of 2-trifluoromethylnitrobenzene stable?
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This compound contains special atomic groups, and its structure results in high chemical activity. From the molecular structure analysis, in 2-trifluoromethyl pyridyl thiazole, trifluoromethyl has strong electron absorption and will change the distribution of molecular electron clouds. The interaction between the pyridine ring and the thiazole ring conjugate system affects the electron density and reactivity check point of the compound.
Due to the strong electron absorption effect of trifluoromethyl, the compound is prone to nucleophilic substitution at a specific check point. When encountering nucleophilic reagents, the low electron cloud density part is easy to be attacked, which prompts the reaction to occur. At the same time, the existence of a conjugated system makes the molecule more likely to participate in electron transfer-related reactions, which further reflects its active chemical properties.
In many chemical reaction scenarios, 2-trifluoromethylpyridyl thiazole exhibits high reactivity and is difficult to maintain its own structural stability. This unstable chemical property makes it an important intermediate in the field of organic synthesis. It participates in the construction of a variety of complex organic compounds by virtue of its reactivity characteristics. By rationally designing the reaction path, the target product can be efficiently synthesized.
What are the synthesis methods of 2-trifluoromethyl nitrobenzene?
To prepare 2-triethylaminobenzoic acid, the following methods can be followed.
First, 2-halobenzoic acid is used as the starting material. Shilling 2-halobenzoic acid is co-heated with dichlorosulfoxide to obtain 2-halobenzoyl chloride. In this step, attention should be paid to the control of the reaction temperature to prevent side reactions. Then 2-halobenzoyl chloride is reacted with triethylamine in a suitable solvent, such as dichloromethane, to obtain 2-triethylaminobenzoic halobenzene. Then 2-triethylaminoformyl halobenzene is treated with n-butyllithium to form a lithium reagent. After reacting with borate esters, such as trimethyl borate, 2-triethylaminoformylphenylboronic acid is obtained by hydrolysis.
Second, 2-aminobenzoic acid is used as the starting material. First, 2-aminobenzoic acid is diazotized, and sodium nitrite and dilute acid are used to obtain diazonium salts. Diazonium salts react with halogenated hydrocarbons catalyzed by copper salts to introduce halogenated atoms to obtain 2-halogenated benzoic acid. The subsequent steps are as described above by using 2-halogenated benzoic acid as the starting material to prepare the target product.
Third, the phenylboronic acid derivative is used as the base. If there is a suitable phenylboronic acid derivative, there are modifiable groups on it, such as ester groups. First hydrolyze the ester group to obtain the corresponding carboxylic acid. After acylation and reaction with triethylamine, 2-triethylaminoformylphenylboronic acid can also be obtained.
All kinds of production methods have advantages and disadvantages. Using 2-halobenzoic acid as the starting material, the raw materials are easy to buy, but the steps are slightly complicated, and multiple steps are required for the reaction and the purification of the intermediate product. With 2-aminobenzoic acid as the starting material, the diazotization reaction requires fine operation and strict reaction conditions. The method based on phenylboronic acid derivatives is simple, but suitable phenylboronic acid derivatives are not easy to obtain and the cost is high. In actual preparation, the most suitable method is selected according to the factors of raw material availability, cost, yield and purity.
What are the precautions for storing and transporting 2-trifluoromethylnitrobenzene?
When storing and transporting di-triethylmethylacetaminobenzene, pay attention to many matters. This is a fine chemical with special properties. When storing and transporting, a little carelessness can easily cause danger, so extreme caution is required.
When it comes to storage, the first priority environment. It must be placed in a cool, dry and well-ventilated place, away from fire and heat sources. Because of its flammability, if the ambient temperature is too high, or in case of open flame, it is very easy to cause combustion or even explosion. And humid environment is not suitable, moisture may react with the substance, causing it to deteriorate, affecting quality and performance.
Furthermore, storage containers need to be carefully selected. Corrosion-resistant materials should be used. Di- triethylacetaminobenzene may react chemically with certain materials, causing damage to the container and leading to leakage. At the same time, the container must be tightly sealed to prevent oxidation and other reactions from coming into contact with air.
As for transportation, it should not be taken lightly. Transportation vehicles must be equipped with complete fire fighting equipment and leakage emergency treatment equipment for emergencies. During loading and unloading, operators should handle it with care, and it is strictly forbidden to drop or pressure to avoid packaging damage. And during transportation, it is necessary to pay close attention to changes in temperature and humidity, and take timely control measures.
In addition, whether it is storage or transportation, it is necessary to strictly follow relevant regulations and standards, and make good signs and records. Make sure that the entire process from storage to transportation is under safe and standardized control, so as to effectively avoid accidents and ensure the safety of personnel and the environment.