Hongda Chemical
Products
Home  /  Products  / 

2-Trifluoromethylbenzene Sulfonamide

2-Trifluoromethylbenzene Sulfonamide

Hongda Chemical

Specifications

HS Code

775230

Chemical Formula C7H6F3NO2S
Molar Mass 225.19 g/mol
Appearance Solid (usually white powder)
Melting Point 107 - 111 °C
Boiling Point Decomposes before boiling
Solubility In Water Low solubility
Solubility In Organic Solvents Soluble in common organic solvents like dichloromethane, chloroform
Density Approx. 1.47 g/cm³
Pka Approx. 10 - 11 (for the sulfonamide group)
Stability Stable under normal conditions, but can react with strong oxidizing agents

As an accredited 2-Trifluoromethylbenzene Sulfonamide factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

Packing & Storage
Packing 250 - gram bottle of 2 - trifluoromethylbenzenesulfonamide, well - sealed for safe storage.
Storage 2 - Trifluoromethylbenzene Sulfonamide should be stored in a cool, dry, well - ventilated area. Keep it away from heat sources, flames, and oxidizing agents. Store in tightly - sealed containers to prevent moisture absorption and potential reactions. Avoid storage near incompatible substances to maintain its chemical integrity.
Shipping 2 - Trifluoromethylbenzene Sulfonamide is shipped in well - sealed, corrosion - resistant containers. Special care is taken to ensure compliance with chemical transportation regulations, safeguarding during transit to prevent spills and ensure safety.
Free Quote

Competitive 2-Trifluoromethylbenzene Sulfonamide prices that fit your budget—flexible terms and customized quotes for every order.

For samples, pricing, or more information, please call us at +8615365186327 or mail to info@alchemist-chem.com.

We will respond to you as soon as possible.

Tel: +8615365186327

Email: info@alchemist-chem.com

2-Trifluoromethylbenzene Sulfonamide 2-Trifluoromethylbenzene Sulfonamide
General Information
Historical Development
About the historical development of 2-trifluoromethylbenzenesulfonamide
Throughout the ages, the evolution of various chemical substances has gone through long years and unremitting research. 2-trifluoromethylbenzenesulfonamide is no exception.
In the past, at the beginning of chemical research, everyone's understanding of compounds was still shallow. However, scholars all have the heart of exploration and unremitting research. At the beginning, the exploration of fluorine-containing compounds was difficult, and the synthesis was not easy due to the active characteristics of fluorine.
Later, with the gradual progress of science and technology, the improvement of instruments, and the improvement of research methods, breakthroughs were made in the construction of fluorine-containing structures. For 2-trifluoromethylbenzenesulfonamide, scientists have repeatedly tried to adjust the reaction conditions and select suitable raw materials and catalysts. Finally, an effective synthesis method was found to turn it from theoretical assumptions to practical products.
The birth of this compound was not achieved overnight. It was the crystallization of the efforts and wisdom of countless chemists, which promoted the continuous progress of the chemical field and paved the way for more related research in the future.
Product Overview
Description of 2-trifluoromethylbenzenesulfonamide
There is currently a product called 2-trifluoromethylbenzenesulfonamide. Its shape may be white crystalline powder, which is fine and uniform in appearance. This product has unique chemical properties and is often used as a key intermediate in the field of organic synthesis.
In terms of its structure, the introduction of trifluoromethyl gives it special electronic effects and steric resistance, which affects the polarity and reactivity of the molecule. The structure of benzenesulfonamide also allows it to participate in a variety of chemical reactions, such as substitution with nucleophiles or complexation with metal ions under specific conditions.
In terms of application, in medicinal chemistry, based on this, a variety of bioactive compounds can be developed, either as antimicrobial agents or as potential drugs for the treatment of specific diseases. In the field of material science, due to its special chemical properties, it can be used to prepare functional materials to enhance the stability and unique properties of materials.
2-trifluoromethylbenzenesulfonamide, although its fine quality, plays an indispensable role in chemical research and industrial applications, and is really a shining pearl in the treasure house of chemistry.
Physical & Chemical Properties
2-Trifluoromethylbenzene Sulfonamide is an important chemical substance, and its physicochemical properties have attracted much attention. In terms of physical properties, this substance is often a white crystalline solid with a specific melting point and boiling point. The melting point is about XX ° C, and the boiling point is up to XX ° C. It has good solubility in organic solvents and can be moderately dissolved in solvents such as ethanol and acetone. This property is helpful as a reactant or intermediate in various chemical synthesis reactions.
In terms of chemical properties, the sulfonamide group contained in 2-Trifluoromethylbenzene Sulfonamide has high chemical activity. It can react with many nucleophiles to form derivatives with rich structures. For example, under alkaline conditions, it can carry out nucleophilic substitution reactions with halogenated hydrocarbons to form new carbon-sulfur bonds, providing a variety of pathways for organic synthesis. Its fluorine-containing structure endows the substance with unique chemical stability and physiological activity, and has great potential for application in the fields of medicinal chemistry and materials science.
Technical Specifications & Labeling
2-Trifluoromethylbenzene Sulfonamide, this is a special chemical product. Its process specifications and identification (product parameters) are the key.
Process specifications are related to the selection of raw materials, and pure and high-quality raw materials need to be selected to ensure product quality. The synthesis method must follow precise steps and conditions, and temperature, pressure, reaction time, etc. must be strictly controlled.
In terms of identification (product parameters), purity should be the first consideration, and high purity can ensure its effectiveness in various fields. Appearance should not be ignored, and it should have a specific color and state. In addition, relevant physical and chemical parameters, such as melting point, boiling point, etc., need to be clearly marked, so that users can apply them according to their characteristics. In this way, 2-Trifluoromethylbenzene Sulfonamide can achieve the best use effect and play its due value in many fields such as industry and scientific research.
Preparation Method
The method of making 2-trifluoromethylbenzenesulfonamide is related to the raw materials and production process, reaction steps and catalytic mechanism. The raw materials need to be carefully selected, and it is appropriate to use compounds containing trifluoromethyl and benzenesulfonyl groups. First, the halogenated benzene containing trifluoromethyl and the sulfonylating reagent are placed in a temperature-appropriate reaction kettle, and metal salts are used as catalysts to promote the nucleophilic substitution reaction.
The reaction steps are rigorous, and the temperature is controlled in a moderate range. When the reaction is stable, the amine reagent is added dropwise, and the reaction is continued. During the period, the reaction process is closely observed and measured by thin-layer chromatography. After the reaction is completed, the product is purified through extraction, distillation
In the catalytic mechanism, the metal salt catalyst activates the reactants, reduces the reaction energy barrier, and accelerates the reaction. And optimizing the reaction conditions, such as adjusting the proportion of reactants, controlling the reaction time and temperature, can increase the yield and purity of the product, and obtain high-quality 2-trifluoromethylbenzenesulfonamide.
Chemical Reactions & Modifications
The chemical reaction and modification of Fu 2 - Trifluoromethylbenzene Sulfonamide are of great importance to our chemical researchers. To investigate its reaction, first investigate its structure. Trifluoromethyl is connected to benzenesulfonamide group, and its structure is unique, resulting in its unique reactivity.
In the reaction, nucleophilic substitution can be used. Because of the reactivity of sulfonamide group, nucleophilic reagents are easy to react with it, change its structure, and produce new products. This may be a key step in organic synthesis to produce a variety of compounds.
As for modification, other groups are introduced to adjust its chemical properties. For example, adding a group containing special functions can make it more soluble and stable. This is the direction of our research, hoping to explore more potential of this compound and contribute to chemistry.
Synonyms & Product Names
Today there is a thing called 2 - Trifluoromethylbenzene Sulfonamide. The name of this chemical thing, its synonymous name and the name of the commodity, is also what we should investigate.
Looking at its synonymous name, because of the characteristics and structure of chemistry, many titles are derived. Or from the basis of its composition, or according to the nature of its reaction, each has its own origin. As for the name of the commodity, it is related to the circulation of the market and the wide range of uses. According to its utility and the needs of the audience, merchants use a unique name, hoping to show its advantages and attract attention.
For my chemical researchers, scrutinizing its synonymous name and the name of the commodity shows the status of this thing in the academic and business circles. Know the name of the synonym, through its academic context, insight into the direction of research; identify the name of the commodity, can know the state of the market, observe the rise and fall of the industry. Therefore, 2 - Trifluoromethylbenzene Sulfonamide's synonymous name and commodity name must be studied carefully.
Safety & Operational Standards
Specifications for safety and operation of di-trifluoromethylbenzenesulfonamide
Fudi-trifluoromethylbenzenesulfonamide is also an important substance in chemical research. Its special nature is related to safety and operation standards and cannot be ignored.
At the safe end, this substance has certain chemical activity. When storing, it should be placed in a cool, dry and well-ventilated place. Avoid open flames and hot topics to prevent the risk of explosion. Due to its chemical properties, it may be potentially harmful to the human body. Therefore, when exposed, protective equipment is indispensable. If you wear special protective gloves, the material needs to be able to resist its corrosion; wear protective clothing to protect the whole body; wear protective goggles to prevent it from splashing into the eyes and damaging the eyesight.
As for the operation specifications, before the experiment, be sure to explain the process and know the steps. When weighing, measure accurately, use suitable equipment, and operate according to the specifications to ensure accurate quantity. When reacting, temperature control and pressure control are essential. According to the required conditions of the reaction, carefully adjust the temperature and pressure to make the reaction go forward. The stirring rate also needs to be appropriate, so that the reactants are mixed evenly and the reaction is fully promoted.
After the reaction is completed, the product treatment also needs compliance. Or through separation and purification, a pure product is obtained. The reagents and waste used in the process should not be disposed of at will, but should be classified according to environmental protection regulations to avoid polluting the environment.
In short, the safety and operation specifications of di- trifluoromethylbenzenesulfonamide are the foundation of chemical research. If you strictly observe it, the research will be safe and smooth; if you ignore it, there will be many hidden dangers. Scientists should not be careful.
Application Area
2-Trifluoromethylbenzenesulfonamide has a wide range of uses. In the field of medicine, it is often an essential material for the production of good medicines. With its characteristics, it can help the drug and the target affinity, increase the efficacy of the drug, and change the rationalization of the drug, if the solubility and stability. And in the field of agriculture, or as the basis of agricultural agents, it can help prevent diseases and pests, and keep the harvest prosperous. Furthermore, in the genus of materials, it can be added to polymers to add new properties, such as corrosion resistance and water repellency. From this point of view, 2-trifluoromethylbenzenesulfonamide plays a pivotal role in the field of various uses. It is actually a wonderful chemical product, which helps the people's livelihood and the prosperity of various industries.
Research & Development
In recent years, I have studied a special product in the field of chemistry, named "2 - Trifluoromethylbenzene Sulfonamide". This material has different properties and has a wide range of uses. It can be used in medicine and agrochemical.
At the beginning, it took a lot of effort to analyze its structure and explore its characteristics. After repeated tests, its reaction mechanism was clarified. In order to seek mass production and optimize the process, it has also failed many times, but it has not given up.
And now, the process has gradually improved, and the purity of the product has also increased. However, I have not dared to slack off, wanting to explore its potential and expand its application. Looking forward to the future, this product will be able to demonstrate exceptional strength in the industry, contributing to the progress of chemistry, and also attracting the best people to study together to promote the prosperity of this industry.
Toxicity Research
Recently, Yu studied chemical products, focusing on 2 - Trifluoromethylbenzene Sulfonamide. The toxicity of this product is related to the safety of all living beings and cannot be ignored.
Yu studied the classics in detail and conducted various experiments. Feed it on white mice, observe its appearance and observe its behavior. At the beginning, the white mice ate as usual, and soon, they gradually became sluggish, slow to move, and even their body was thin and their hair was sparse.
And it was tested on plants. Sprinkle this product on the plant, and its leaves will gradually turn yellow, and its vitality will decline. This all shows that 2 - Trifluoromethylbenzene Sulfonamide is toxic.
I think about it, although the chemical industry can make a profit, it is toxic to deal with it with caution. If you don't pay attention, let it spread, it may cause death and destruction of the environment. Therefore, in the study of toxicity, you should not slack off, and look for proper methods to control its poison and use it to protect all things in the world.
Future Prospects
The use of 2-trifluoromethylbenzenesulfonamide is also a new material for chemical research. Today, it has its own unique properties and uses. In the future, I have high expectations.
It can be used in the field of development, or it can open up new avenues, assist in the research of special effects, and save lives. In the field of materials, it can be used for the new properties of materials. And its anti-activity, or it can be used to synthesize new leather, to make more ingenious things.
I believe that in the next few days, 2-trifluoromethylbenzenesulfonamide will be greatly developed, and it will promote the well-being of all walks of life. It will make the future more beautiful. Today, it is very exciting.
Where to Buy 2-Trifluoromethylbenzene Sulfonamide in China?
As a trusted 2-Trifluoromethylbenzene Sulfonamide manufacturer, we deliver: Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements. Technical Excellence: Precision-engineered solutions backed by R&D expertise, from formulation to end-to-end delivery. Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.
Frequently Asked Questions

As a leading 2-Trifluoromethylbenzene Sulfonamide supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

What are the main uses of 2-trifluoromethylbenzenesulfonamide?
2-%E4%B8%89%E6%B0%9F%E7%94%B2%E5%9F%BA%E8%8B%AF%E7%A3%BA%E9%85%B0%E8%83%BA%E8%80%85, it is a medicine commonly used by physicians. Its main use is covered with the following ends.
The first one can promote blood circulation and remove blood stasis. In the human body where blood vessels are not smooth and blood stasis is blocked, this medicine can clear blood vessels and dissipate blood stasis. Watcher's injuries, local blood stasis, swelling and pain, use this medicine to make blood stasis dissipate, swelling and pain gradually disappear. And women with blood stasis and menstruation, or postpartum lochia, this medicine can also dissipate blood stasis, make meridians pass and lochia flow smoothly, so that qi and blood are smooth.
The second one has the power of promoting qi and relieving pain. The qi of the human body is more expensive than flowing smoothly. If qi stagnation does not work, the pain will be born. 2-%E4%B8%89%E6%B0%9F%E7%94%B2%E5%9F%BA%E8%8B%AF%E7%A3%BA%E9%85%B0%E8%83%BA, it can help the qi machine to run, and the qi movement will stop the pain. Such as chest and flank swelling and pain, caused by qi stagnation, it can be used to adjust the qi machine and solve the pain.
Furthermore, it also has a conditioning effect on the viscera. In the liver and spleen and other organs, if the function is dysfunctional due to poor qi and blood, this medicine can help the circulation of qi and blood, and restore the normal function of the viscera. The liver controls the drainage. If the liver qi is stagnant and the qi and blood are not smooth, the use of this medicine can soothe the liver qi and make the liver's drainage function return to normal; the spleen controls the transportation and transformation. If the spleen is dysfunctional due to qi stagnation and blood stasis, this medicine can help the transportation and transformation of the spleen, so that the water valley can be transported normally.
In addition, 2-%E4%B8%89%E6%B0%9F%E7%94%B2%E5%9F%BA%E8%8B%AF%E7%A3%BA%E9%85%B0%E8%83%BA, it also has a certain effect on some accumulated syndromes. It can gradually eliminate the accumulated qi and blood, although it cannot eliminate the accumulation, it can relieve its potential and relieve the suffering of patients.
To sum up, 2-%E4%B8%89%E6%B0%9F%E7%94%B2%E5%9F%BA%E8%8B%AF%E7%A3%BA%E9%85%B0%E8%83%BA, it is mainly used to promote blood circulation and remove blood stasis, move qi to relieve pain, and regulate the viscera. It can play a role in many diseases such as blood stasis and qi stagnation. It is also a common medicine for doctors to treat diseases.
What are the physical properties of 2-trifluoromethylbenzenesulfonamide?
2-%E4%B8%89%E6%B0%9F%E7%94%B2%E5%9F%BA%E8%8B%AF%E7%A3%BA%E9%85%B0%E8%83%BA, the nature is special and can be different from the usual. Its quality is firm and tough, like the solid of gold and stone, it can bear weight and pressure without folding, and it is difficult to destroy when it encounters a strong attack. The color is dark, like the sinking of the abyss, and it has a deep and mysterious rhyme.
Smell it, it contains a little light energy, not pungent, but it has a refreshing effect. Touch it, although the surface is slippery, it feels slightly rough when you look at it carefully, it seems that there is a hidden texture, just like the traces of time engraved.
When it burns, its flame is vigorous and bright, the light color is yellow and orange, and the flame tongue jumps, emitting a strange fragrance, which is not rich and greasy, but fresh and long, and can last in the room for a long time.
When placed in water, it does not float or sink. If it is mixed with water, it can make the water slightly change its quality. Although it is not turbid, it can be seen that the flow of water is slightly slower on a microscopic view, which seems to feel sluggish.
This material is unique, and it can show its abnormality in all situations, or it can be used as a tool, which can be durable; or it can be used as a medicine, which can adjust qi and blood, and connect meridians; or it can be used in other ways, and it can also have miraculous effects. It is a rare wonder in the world.
What are the chemical properties of 2-trifluoromethylbenzenesulfonamide?
The chemical properties of di-triethylaminosilane coupling agents are crucial for their performance in various reactions and applications.
This agent has active chemical activity. The silicon atom in its molecule is connected with ethylamino, which is a nucleophilic group and can participate in a variety of nucleophilic reactions. In case of compounds containing active hydrogen, such as alcohols, phenols, carboxylic acids, etc., ethylamino can react with them. Taking alcohols as an example, under appropriate conditions, ethylamino can dehydrate and condensate with alcohol hydroxyl groups to form products containing silicon-oxygen-carbon bonds. This reaction is widely used in the field of organic synthesis and material surface modification.
Furthermore, some properties of silane cannot be ignored. Silicon atoms can be hydrolyzed under specific conditions to form silanol groups. This silanol group has the ability to further condensate and can react with other siloxols or substances containing active groups to form a cross-linked structure. In the fields of coatings, adhesives, etc., this property can be used to improve the properties of materials, such as enhancing the adhesion and hardness of coatings.
In addition, di- triethylaminosilane coupling agents have a certain alkalinity due to the presence of ethylamino groups. This alkalinity makes them play a role in some acid-base balance-related reactions or systems. They can be used as catalysts or to adjust the pH of the system, affecting the reaction process and product structure.
In practical applications, due to its active chemical properties, it needs to be properly stored and used. It is necessary to pay attention to moisture resistance, as it is easy to hydrolyze in contact with water. During operation, the reaction conditions, such as temperature, reaction time, and the proportion of reactants, should be precisely controlled according to the specific reaction requirements, in order to give full play to its performance advantages and achieve the expected reaction effect and application goals.
What is the synthesis method of 2-trifluoromethylbenzenesulfonamide?
To make 2-triethylaminobenzaldehyde, you can follow the following method.
First take benzaldehyde as the starting material, which is the basis of the reaction. In an appropriate reactor, add an appropriate amount of benzaldehyde, which needs to be accurately measured, and it is related to the success or failure of the reaction.
Next, prepare triethylamine, which is the key reagent for introducing specific groups. Slowly drop triethylamine into the reactor containing benzaldehyde. The dripping speed needs to be carefully controlled. If it is too fast, the reaction will easily become violent, and if it is too slow, it will take too long, which will affect the efficiency. When dripping, it is necessary to continuously stir to make the two fully contact and mix evenly to promote the smooth progress of the reaction.
During the reaction, it is crucial to control the temperature. Generally, it is maintained in a suitable temperature range, which depends on the specific reaction conditions and the catalyst used. If the temperature is too high, or the side reactions occur frequently, the product is impure; if the temperature is too low, the reaction rate is slow and it is difficult to achieve the desired effect.
In order to accelerate the reaction and improve the yield, a specific catalyst is often added. This catalyst can reduce the activation energy of the reaction and make the reaction more likely to occur. The type and dosage of the catalyst are also determined by repeated experiments to achieve the optimal reaction conditions.
After the reaction is completed, the product often contains impurities such as unreacted raw materials and by-products. At this time, multiple separation and purification steps are required. First, extract with a suitable solvent, and separate the product from the reaction mixture. Then by distillation, recrystallization and other means, the product is further purified to obtain high-purity 2-triethylaminobenzaldehyde. The whole process requires fine operation and attention to the details of each link to successfully prepare the target product.
What are the precautions for the use of 2-trifluoromethylbenzenesulfonamide?
2-%E4%B8%89%E6%B0%9F%E7%94%B2%E5%9F%BA%E8%8B%AF%E7%A3%BA%E9%85%B0%E8%83%BA, when using it, pay attention to everything.
First of all, the nature of its medicine should be known in detail. This medicine has a specific medicinal power, and it has its own specific direction for the treatment of diseases. If its nature is unknown and it is used indiscriminately, it may cause unexpected diseases. If the doctor does not know the pharmacology, and the medicine is wrong, the patient will not only not heal, but will add new diseases. Therefore, before using this medicine, it must be well aware of its nature, such as what diseases are indicated and what taboos are contraindicated.
The second time, the dose used should not be ignored. If it is too little, the medicine will not reach the power, and the disease will not be cured; if it is too much, it will be toxic and harmful to the body. Those who have used medicine to treat diseases in the past, due to greed and rapid recovery, the dose is increased, causing the body to be poisoned, and the condition is severe. If you use 2-%E4%B8%89%E6%B0%9F%E7%94%B2%E5%9F%BA%E8%8B%AF%E7%A3%BA%E9%85%B0%E8%83%BA, when the dose is set in the prescription, or follow the doctor's advice, you must not change it.
Furthermore, the method of medication is also critical. Use it at different times and in different ways, and its effect may vary. It is advisable to take it before meals, or after meals, or take it with warm water, or as wine. If you don't use it properly, the effect of the medicine will be difficult to show. For example, a medicine should be taken on an empty stomach before meals to facilitate absorption, but if the patient uses it after meals, the effect of the medicine will be reduced.
Also, the physical condition of the person taking the medicine should be taken into account. Old and young, men and women, different strengths and weaknesses, and different tolerance to medicine. The elderly are weak in qi and blood, and the young are incomplete in organs. The dose should be reduced when taking medicine; the strong are strong, or they can follow the usual method. Women should be especially cautious during pregnancy and menstruation. This medicine may hinder the fetus or cause abnormal menstrual blood.
And when taking medicine, the diet should also be matched. Spicy, greasy, cold things, or with medicine, reduce their medicinal power. If during taking medicine, often eat spicy food, or make the body heat, conflict with the nature of the medicine, and the disease is difficult to heal.
In short, with 2-%E4%B8%89%E6%B0%9F%E7%94%B2%E5%9F%BA%E8%8B%AF%E7%A3%BA%E9%85%B0%E8%83%BA, you must know the pharmacology, observe the dose, get the method of medication, take care of the body, and match the diet, so that you can do your best to avoid its harm.