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2-(Trifluoromethyl)Benzene-1-Carbonyl Chloride

2-(Trifluoromethyl)Benzene-1-Carbonyl Chloride

Hongda Chemical

    Specifications

    HS Code

    457453

    Chemical Formula C8H4ClF3O
    Molecular Weight 210.564
    Appearance Colorless to light yellow liquid
    Boiling Point 193 - 194 °C
    Melting Point N/A
    Density 1.387 g/mL at 25 °C
    Flash Point 74.4 °C
    Solubility Reacts with water, soluble in organic solvents
    Vapor Pressure N/A
    Refractive Index 1.472

    As an accredited 2-(Trifluoromethyl)Benzene-1-Carbonyl Chloride factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing 500g of 2-(trifluoromethyl)benzene - 1 - carbonyl chloride in sealed glass bottle.
    Storage 2-(Trifluoromethyl)benzene - 1 - carbonyl chloride should be stored in a cool, dry, well - ventilated area, away from heat, ignition sources, and moisture. It must be stored in a tightly sealed container, preferably made of corrosion - resistant materials. Keep it separate from incompatible substances like bases, alcohols, and water to prevent hazardous reactions.
    Shipping 2-(Trifluoromethyl)benzene - 1 - carbonyl chloride is a hazardous chemical. Shipping requires proper containment in corrosion - resistant containers, following strict regulations for handling and transporting corrosive and toxic substances to ensure safety during transit.
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    2-(Trifluoromethyl)Benzene-1-Carbonyl Chloride 2-(Trifluoromethyl)Benzene-1-Carbonyl Chloride
    General Information
    Historical Development
    In the field of chemical industry, substances proliferate, and today there is 2- (trifluoromethyl) benzoyl chloride. Its beginning is also due to the fact that many wise men studied at the end of the micro and went through various trials, and then they found clues. At the beginning, the skills were not refined, and if you wanted to make this thing, it was difficult to reach the sky. All kinds of attempts, or fruitless, or little success.
    However, the heart of a scholar, perseverance, reluctant to give up day and night, to introduce new ones on the ancient method. Looking at the documents of the past, studying the losses of predecessors, changing to new agents, adjusting their heat, and changing their order. After years of work, gradually achieved success. Since then, the preparation of 2- (trifluoromethyl) benzoyl chloride has become increasingly perfect, the output has gradually increased, and the application has also been wide. It has shown its ability in the pharmaceutical and material industries, becoming a brilliant stroke in the history of chemical industry.
    Product Overview
    Today there is a substance called 2- (trifluoromethyl) benzoyl chloride. Its shape may be colorless to light yellow liquid with a pungent smell. This substance has a wide range of uses in the field of organic synthesis.
    The cap is active because it contains trifluoromethyl and benzoyl chloride groups. In chemical reactions, benzoyl chloride groups can participate in many acylation reactions, interact with alcohols, amines, etc., to form esters, amides and other compounds, which are crucial in the synthesis of drugs and fragrances. The introduction of trifluoromethyl can significantly change the physical and chemical properties of compounds, such as improving fat solubility and enhancing stability.
    However, this compound is corrosive. When operating, you must be careful and well protected to avoid hurting yourself. And its storage also needs to pay attention to the environment, avoid moisture and heat, and prevent deterioration. In this way, this compound can be used well for chemical research and industrial production.
    Physical & Chemical Properties
    2 - (trifluoromethyl) benzene - 1 - carbonyl chloride, the physical and chemical properties of this substance are the key. It has special physical properties, and it may take a specific form at room temperature, or have a unique color and taste. From the perspective of chemical properties, due to the specific functional groups it contains, its activity is unique. The existence of trifluoromethyl gives it some special chemical activities, making it behave differently in various chemical reactions. The carbonyl chloride functional group also allows it to participate in a variety of classic organic synthesis reactions, such as acylation reactions. It can react with many nucleophiles to form new chemical bonds, thereby deriving a variety of organic compounds. Only by studying its physical and chemical properties in detail can we make good use of it in the fields of chemical synthesis and material preparation, tap its potential value, and contribute to the development of related fields.
    Technical Specifications & Labeling
    "On the Process Specification and Identification (Product Parameters) of Bis (Trifluoromethyl) Benzene-1-formyl Chloride"
    This is an important chemical product. The process specification is related to the preparation process. First, the raw materials need to be selected and the purity controlled. For example, the benzene and fluorinated reagents used must meet specific standards. The reaction conditions are also critical. The temperature should be controlled in a certain range, and the pressure needs to be consistent, so as to ensure the efficient and stable reaction.
    In terms of identification, the product parameters should be clear. Its appearance and color need to be accurately described, and the content data should be accurately marked. On the packaging, there should be a conspicuous label indicating the name, chemical formula, and warning information to clarify its characteristics and risks, so that the user can understand the details, ensure safe operation, and ensure the orderly circulation of this product in industrial applications.
    Preparation Method
    To prepare 2 - (trifluoromethyl) benzoyl chloride, the method is as follows:
    Take the raw material first, and prepare 2 - (trifluoromethyl) benzoic acid, which is the key. Sulfuryl chloride is used as the reaction reagent, and the two are mixed in an appropriate proportion.
    Reaction step, place the above mixture in a reactor, slowly heat up, to a moderate temperature, about [X] ° C, keep constant temperature, so that it can fully react. This process needs to pay attention to the control of temperature, do not make it too high or too low, so as not to affect the yield.
    Catalytic mechanism, sulfuryl chloride is a good agent in this reaction, its chlorine atom is active, and it can interact ingeniously with the carboxyl group of benzoic acid to convert the carboxyl group into an acyl chloride group.
    After this operation, 2 - (trifluoromethyl) benzoyl chloride can be obtained. However, the product or impurities need to be purified to obtain high purity.
    Chemical Reactions & Modifications
    In recent years, the chemical product has been studied to obtain 2- (trifluoromethyl) benzoyl chloride. Observing its chemical reaction and property change, I have some insight.
    At the beginning, when looking at the chemical reaction of this chlorine, it mostly follows the conventional way. When it meets with alcohol, it will form an ester, and it will also be smooth, if it is in line. However, if you want to find the beauty of its property change, you need to study it further.
    If you want to change its properties, think of different ways to adjust it. Or change the environment, control the temperature and pressure; or add other agents to introduce new bases into it. If you add a certain agent to it, you will get a different product, and its properties are very different from usual. This change is also like the light in the dark night, opening up a new path for us.
    Although the gains are still shallow, the way to change and change is gradually becoming more and more reasonable. Those who look forward to the future will follow my exploration and use it to make the best use of this chlorine to the world, adding brilliance and brilliance to the chemical industry.
    Synonyms & Product Names
    2 - (trifluoromethyl) benzene-1-formyl chloride, this substance is used in the field of chemical industry and has a wide range of uses. Its synonym and trade name are also important in the industry.
    Looking back at the past, chemists have given different names to identify different chemicals when exploring the properties and uses of substances. 2 - (trifluoromethyl) benzene-1-formyl chloride, its synonym or according to its structural characteristics and synthesis path. Or due to different raw materials and reaction conditions, its name is different.
    As for the trade name, in order to make the product stand out in the market and attract customers, merchants often take easy-to-remember and identifiable names. The trade name of this chemical, or related to its application field and unique properties, helps users quickly identify its value.
    At the moment, knowing the synonym and trade name of 2 - (trifluoromethyl) benzene-1 - formyl chloride is of key significance in chemical production and scientific research. It can avoid communication and misunderstanding and promote the smooth development of the industry.
    Safety & Operational Standards
    Safety and Handling Specifications for 2- (Trifluoromethyl) Benzoyl Chloride
    2- (Trifluoromethyl) benzoyl chloride is a common chemical in chemical research. Its nature is lively, and many safety and regulatory matters must be carefully paid attention to during use and operation.
    First word safety protection. This chemical is corrosive and can cause serious burns when it touches the skin and eyes. Therefore, when operating, complete protective equipment must be worn, such as acid and alkali resistant protective clothing, protective gloves, and goggles must be worn to prevent liquid from splashing into the eyes. If you accidentally touch the skin, you should immediately rinse with a large amount of water, and then seek medical treatment; if you splash into the eyes, you need to rinse with a large amount of flowing water immediately, for not less than 15 minutes, and quickly seek treatment in the ophthalmology department.
    Furthermore, it is related to the operating environment. Because of its irritating odor and possible volatilization of harmful gases, the operation should be carried out in a well-ventilated environment, preferably in a fume hood. At the same time, it should be kept away from fire and heat sources, because it is exposed to open flames, hot topics, or the risk of combustion and explosion.
    Operating specifications should not be ignored. When taking this chemical, be sure to measure it accurately to avoid waste and excessive use. After use, properly seal and store in a cool, dry and ventilated place, away from incompatible substances to prevent chemical reactions. If there is any discarded 2- (trifluoromethyl) benzoyl chloride, it must not be discarded at will, and it must be treated harmlessly in accordance with relevant regulations.
    In short, the use of 2- (trifluoromethyl) benzoyl chloride in chemical research can only ensure the safety of researchers and ensure the smooth conduct of experiments to avoid accidents.
    Application Area
    2 - (trifluoromethyl) benzene - 1 - carbonyl chloride, this compound has a wide range of uses. In the field of medicine, it can be used as a key intermediate to help synthesize drugs with specific curative effects to cure a variety of diseases. In the field of materials science, with its unique chemical properties, it can improve material properties, such as enhancing material stability and corrosion resistance. In the field of organic synthesis, it is an important building block for building complex organic molecules. With its active groups, it can be reacted to construct complex organic compounds, providing assistance for the development of organic synthetic chemistry. It has many uses and is of great value in many application fields, promoting the progress and development of related industries.
    Research & Development
    Today, there is a product named 2- (trifluoromethyl) benzoyl chloride, which is very important in the field of my chemical research. Our generation devoted themselves to studying its characteristics, production methods and applications, hoping to make progress in the chemical industry.
    At the beginning of the study, we carefully observed its physicochemical properties. How this material is, the point of melting and dissolution are all important concerns. Explore its structure, clarify chemical bonds, and lay the foundation for subsequent research.
    Then study the method of preparation. Or there are old methods to follow, but strive to innovate, hoping to achieve high efficiency and environmental protection. Improving the process, reducing energy consumption and reducing pollution are the pursuit of our generation.
    As for the application, it can involve many fields such as medicine and materials. In medicine, it may be a key raw material for synthesizing new drugs; in materials, it may give it specific properties.
    We persevere and study this substance, hoping to promote the development of the chemical field, leaving usable results for future generations, so that this research can be continuously passed down and increasingly refined.
    Toxicity Research
    Toxicity Study of 2- (Trifluoromethyl) Benzoyl Chloride
    Recent research on the toxicity of 2- (trifluoromethyl) benzoyl chloride, which is related to people's livelihood and the environment, is a matter of great importance. The appearance of this compound is colorless to slightly yellow liquid, and it has a pungent smell.
    Experiments have shown that it has many effects on animals. If mice are used as a test, inhaling this gas, mice may suffer from shortness of breath and coughing, which can cause lung damage for a long time. When the skin touches it, there may be redness, swelling, and burning, indicating that it is irritating.
    Analyze its impact on the environment, in aquatic ecology, or endanger aquatic organisms. Due to its chemical properties, it degrades slowly in the natural environment and is easy to accumulate.
    Overall, the toxicity of 2- (trifluoromethyl) benzoyl chloride should not be underestimated. During production and use, strict protective measures should be taken to reduce its harm to life and the environment, and to maintain ecological safety and people's livelihood.
    Future Prospects
    Today, there is a thing called 2- (trifluoromethyl) benzoyl chloride. I am optimistic about it, and its future development can be seen. This thing has extraordinary potential in the field of organic synthesis.
    With its chemical properties, it can be used as a raw material for many exquisite syntheses. In the future, it may shine on the road of pharmaceutical creation. It can assist researchers in making special drugs to treat difficult diseases in the world. It is also expected to emerge in the road of materials science, giving rise to novel materials, and responding to diverse needs.
    Although there may be thorns in the road ahead, but technology is advancing day by day, I believe it will be able to break through the obstacles. With time, it will be able to contribute to the well-being of mankind and develop an infinite future.
    Where to Buy 2-(Trifluoromethyl)Benzene-1-Carbonyl Chloride in China?
    As a trusted 2-(Trifluoromethyl)Benzene-1-Carbonyl Chloride manufacturer, we deliver: Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements. Technical Excellence: Precision-engineered solutions backed by R&D expertise, from formulation to end-to-end delivery. Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.
    Frequently Asked Questions

    As a leading 2-(Trifluoromethyl)Benzene-1-Carbonyl Chloride supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

    What are the main uses of 2- (trifluoromethyl) benzoyl chloride?
    The main use of (triethyl) silicoethylboronic acid is an important function in the multi-domain.
    First, it can be used for the fabrication of semi-components, liquid crystal displays and other sub-components. Because of its qualitative properties, it can effectively improve the performance and reliability of sub-components. For example, in the semi-fabrication process, (triethyl) silicoethylboronic acid can be used to form high-quality products, blocking different channels, preventing leakage, and ensuring semi-normal operation.
    Second, in terms of optical materials, this compound also has a high value. It has good optical properties and can be used in optical glass, optical materials and other materials. With the obtained optical material, it can effectively improve the refraction of the optical device and improve the image quality of the optical device. For example, in high-resolution optical materials, adding (triethyl) silicoethylboronic acid can improve the light transmittance and dispersion properties of the film, making the image of the film clearer and more realistic.
    Furthermore, in the bonding field of the material, (triethyl) silicoethylboronic acid is also important. Adding it to the material can increase the hardness, wear resistance, chemical corrosion resistance, and service life of the film. In bonding, it can improve the adhesion and weather resistance of the adhesive, making the bonding effect stronger and longer lasting.
    In addition, in the catalytic domain, (triethyl) silicoethylboronic acid can be used as a catalyst or catalyst for some synthetic reactions. With its special properties, it can effectively promote the reaction, improve the reaction rate, and promote the development of synthetic reactions.
    What are the physical properties of 2- (trifluoromethyl) benzoyl chloride?
    (Trisemethyl) silylacetonitrile oxide is an important compound in organic synthesis. Its physical properties are as follows:
    Looking at its appearance, under room temperature and pressure, (Trisemethyl) silylacetonitrile oxide is mostly colorless to light yellow liquid, uniform and clear in texture, good light transmittance, and no obvious suspended solids or precipitation.
    When it comes to boiling point, the boiling point of this compound is in a specific range. Due to factors such as intermolecular forces, its boiling point causes the substance to change from liquid to gaseous at a certain temperature. Accurately knowing the boiling point is of great significance in experimental operations such as separation and purification. It can be precisely separated from the mixture by distillation and other means according to the difference in boiling points.
    Besides the melting point, the melting point of (trisesomethyl) silylacetonitrile oxide is also a key physical parameter. The melting point defines the temperature node of the transformation of a substance from a solid to a liquid state, which has a great impact on the determination of storage and use conditions. If the storage temperature is higher than the melting point, the substance is in a liquid state, and it needs to be prevented from leaking; if it is lower than the melting point, it is in a solid state. When taking it, you need to pay attention to the way of taking it.
    Its density is also a physical property that cannot be ignored. At a specific temperature and pressure, (trisesomethyl) silylacetonitrile oxide has a specific density value. This value is of great significance for operations such as accurate measurement and calculation of the proportion of reaction materials. For example, in a chemical reaction, the mass of the substance can be accurately obtained according to the density and volume, thereby ensuring that the reaction proceeds according to the expected stoichiometric ratio, and the reaction yield and product purity are improved.
    In terms of solubility, (trisesomethyl) silyl acetonitrile oxide exhibits good solubility in some organic solvents, such as common ether, dichloromethane, etc. This solubility characteristic provides convenience for organic synthesis reactions. Appropriate solvents can be selected to make the compound fully contact and mix with other reactants to promote the smooth occurrence of the reaction. In water, its solubility is poor, and this characteristic can be exploited in post-reaction treatment and other processes to achieve preliminary purification of the product through the separation of aqueous and organic phases.
    What are the chemical properties of 2- (trifluoromethyl) benzoyl chloride?
    (Sanxiang methyl) naphthalene methyl ether iodide, its chemical properties can be investigated. In this compound, the naphthalene ring is aromatic, giving it a certain stability and a special electron cloud distribution. The methyl group attached to the naphthalene ring can affect its electron cloud density, resulting in different reactivity at specific positions of the naphthalene ring. The existence of
    ether bonds makes the molecule have a certain polarity, which affects its solubility and intermolecular forces. As a leaving group, the iodine atom has high electronegativity, and under suitable conditions, it is easy to leave and initiate reactions such as nucleophilic substitution.
    In the nucleophilic substitution reaction, after the iodine ion leaves, the nucleophilic reagent can attack the carbon atom connected to the methyl group of the naphthalene ring. Due to the distribution of the electron cloud of the naphthalene ring, the attack check point has a certain selectivity. And ether bonds also affect the reactivity, which can be promoted or hindered by electronic effects or spatial effects.
    When encountering basic reagents, the part of the molecule may be affected or eliminated. Its chemical properties are controlled by the synergy of various groups in the molecule, and the groups interact with each other. Under different reaction conditions, it exhibits a variety of chemical behaviors. It is an important object of organic chemistry research. The exploration of its properties is of great significance in many fields such as organic synthesis and drug development.
    What is the preparation method of 2- (trifluoromethyl) benzoyl chloride?
    The method of preparing triethylbenzyl chlorophenyl ether is obtained by reacting benzyl chloride with triethoxybenzene under appropriate conditions.
    First take an appropriate amount of benzyl chloride, which is the starting material for the reaction. Benzyl chloride has active chemical properties and can provide benzyl moiety in the reaction. It is prepared or obtained from the reaction of the corresponding benzyl alcohol with a chlorination reagent. The chlorination reagent used, such as thionyl chloride, phosphorus trichloride, etc., is at a suitable temperature and reaction environment. The hydroxyl group of the benzyl alcohol is replaced by a chlorine atom to obtain benzyl chloride.
    Another triethoxybenzene is prepared, which is also the key raw material. The synthesis of triethoxylbenzene, or the substitution reaction between benzene and ethanol under the action of a specific catalyst, the hydrogen atom on the benzene ring is replaced by ethoxy group, so as to obtain.
    The benzyl chloride and triethoxylbenzene are placed in the reaction vessel, and an appropriate amount of catalyst, such as some metal salts or organic bases, is added. The reaction temperature needs to be carefully controlled, generally maintained in a moderate range. Too high or too low temperature can affect the reaction rate and the purity of the product. During the reaction, the benzyl part of the benzyl chloride will undergo a nucleophilic substitution reaction with triethoxylbenzene, and the benzyl group will replace the atom at a certain position on the triethoxylbenzene ring to gradually generate triethylbenzyl chlorophenyl ether
    After the reaction is completed, the product needs to go through the steps of separation and purification. The crude product can be separated by methods such as distillation, using the boiling point difference between the product and the unreacted raw materials and by-products. Then it is further purified by recrystallization or column chromatography to remove impurities and improve the purity of the product. Finally, pure triethylbenzyl chlorophenyl ether is obtained.
    What are the precautions for the storage and transportation of 2- (trifluoromethyl) benzoyl chloride?
    In the storage and transportation of (trichloromethyl) siloxy silane, many key matters need to be paid attention to.
    One is the storage environment. This substance should be stored in a cool, dry and well-ventilated place. Because the substance is quite sensitive to humidity, humid environments are prone to hydrolysis and deterioration. If stored in a humid place, moisture intrusion will trigger chemical reactions, change its chemical structure and properties, and greatly affect the subsequent use effect.
    The second is about temperature control. High temperature environments should be avoided, and storage temperatures should not be too high. High temperatures will accelerate the rate of chemical reactions, resulting in adverse reactions such as decomposition or polymerization. When the temperature is too high, the molecular activity will increase, which is easy to cause self-reaction, and may even cause safety hazards, such as combustion and explosion.
    The third is the packaging requirements. Packaging materials with good sealing performance must be used. Sealed packaging can effectively isolate air and moisture and prevent external factors from interfering. If the packaging is not well sealed and air and moisture seep in, it will affect the stability of the material and reduce the quality of the product.
    Fourth, in terms of transportation. It is necessary to ensure that the packaging is intact during transportation. The bumps in the road may cause damage to the packaging. Once the packaging is damaged and the material leaks, it will not only cause losses, but also pose a threat to the transportation personnel and the surrounding environment. And the transportation vehicle needs to have corresponding protective measures to prevent the external environment from adversely affecting it.
    Fifth, it should be stored and transported separately from other chemicals. Due to its unique chemical properties, contact with certain chemicals may cause violent chemical reactions, resulting in dangerous conditions. Therefore, during storage and transportation, it is necessary to strictly follow relevant specifications to ensure the safety and stability of (trichloromethyl) siloxysilane.