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2-(Trifluoromethyl)Benzene-1,4-Diamine

2-(Trifluoromethyl)Benzene-1,4-Diamine

Hongda Chemical

Specifications

HS Code

820245

Chemical Formula C7H7F3N2
Molecular Weight 176.14
Appearance Solid (usually white to off - white powder)
Melting Point Specific value depends on purity, typically in a certain range
Solubility In Water Low solubility
Solubility In Organic Solvents Soluble in some polar organic solvents like DMSO, DMF
Density Calculated or experimentally determined value
Flash Point Relevant value indicating fire hazard
Pka Value Value related to its acidic - basic properties
Vapor Pressure Low vapor pressure

As an accredited 2-(Trifluoromethyl)Benzene-1,4-Diamine factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

Packing & Storage
Packing 250g of 2-(trifluoromethyl)benzene - 1,4 - diamine in sealed plastic bags for safe storage.
Storage 2-(Trifluoromethyl)benzene - 1,4 - diamine should be stored in a cool, dry, well - ventilated area. Keep it away from heat sources, open flames, and oxidizing agents. Store in a tightly sealed container, preferably in a corrosion - resistant material, to prevent moisture and air from degrading the chemical. Avoid storage near incompatible substances to ensure safety.
Shipping 2-(Trifluoromethyl)benzene - 1,4 - diamine is shipped in sealed, corrosion - resistant containers. Strict compliance with chemical shipping regulations ensures safe transport, safeguarding against spills and environmental exposure.
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2-(Trifluoromethyl)Benzene-1,4-Diamine 2-(Trifluoromethyl)Benzene-1,4-Diamine
General Information
Historical Development
The past, the field of chemistry, has not been explored yet. There is a thing called 2 - (trifluoromethyl) benzene-1,4 - diamine, and when it began, its properties were not known to everyone. The wise men thought hard and studied unremitting.
At the beginning, only a little bit of its appearance was known, but its function was at a loss. Afterwards, after countless trials and errors, it gradually became clear of its characteristics. At that time, the equipment was simple, and the analysis was difficult. However, those who were determined were not hindered.
With the passage of time and the advancement of science and technology, the method of studying this thing is getting better and better. In medicine and materials, it gradually shows its amazing ability. Or it is the basis for new agents, or it helps materials to rejuvenate.
Looking at the process of its development, from the unknown to the insight, the hearts of all people are blood coagulated. Today, 2- (trifluoromethyl) benzene-1,4-diamine has become an indispensable item in the chemical treasure house, and future generations should also carry on the ambition of the past and continue to explore the mystery of chemistry.
Product Overview
2 - (trifluoromethyl) benzene - 1,4 - diamine is a unique chemical substance. Its color is pure, in a crystalline state, shining under the light, as if the stars are falling.
This substance has stable properties, but it can also exhibit its active chemical activity in a specific reaction environment. It plays a crucial role in the field of organic synthesis. It can be used as a key intermediate, and many compounds with special properties can be derived through ingenious chemical reactions.
Due to its molecular structure, the introduction of trifluoromethyl gives this substance unique physical and chemical properties. It has potential application value in materials science, medicinal chemistry and many other fields. Chemists are making great efforts to explore its characteristics in depth, hoping to open up a wider application world for the benefit of human production and life.
Physical & Chemical Properties
The physical and chemical properties of 2 - (trifluoromethyl) benzene - 1,4 - diamine are related to many aspects. The appearance of this substance may be in a specific state, or in a crystalline form, and whether it is pure or not is its physical appearance. Its melting point and boiling point also have key characteristics. The melting point is also related to the temperature of its phase transition, the number of boiling points, and the energy required for its gasification.
On chemical properties, because it contains specific groups, such as trifluoromethyl and diamine, its reactivity is unique. The strong electron absorption of trifluoromethyl makes the distribution of molecular electron clouds unusual, which affects its nucleophilic and electrophilic reactions. Diamine groups can participate in many condensation and substitution reactions. In the field of organic synthesis, they can be used as important intermediates to react with alcaldes and ketones to construct various heterocycles or macromolecular structures. Its solubility varies in different solvents. In polar solvents or non-polar solvents, the dissolution performance is an important characterization of its physical and chemical properties.
Technical Specifications & Labeling
For 2 - (trifluoromethyl) benzene-1,4-diamine, it is also a chemical compound. Its technical quality is high (product quality) to the most important. Only when it is high in quality, high in quality, and low in quality can it be suitable for use. Its outer appearance, shape, or crystal shape, and color must also be uniform. As for the product, the name of the product, its ingredients, and warnings of danger are all clear and clear. In this way, its properties and uses can be known, so that it can be used properly in production and production, avoiding its harm and obtaining its benefits, so as to study the work of manufacturing.
Preparation Method
The method of making 2 - (trifluoromethyl) benzene - 1,4 - diamine is crucial to the raw materials and production process, reaction steps and catalytic mechanism. The raw materials are selected from high-quality products to ensure the purity of the product. In the production process, an appropriate amount of fluorine-containing reagents is first taken, and the specific benzene derivatives are put into the reactor according to the precise ratio. The appropriate temperature and pressure are controlled, and the high-efficiency catalyst is used to fully blend the two. At the beginning of the reaction step, the two slowly combine and the molecular structure gradually changes. After several hours, the reaction stabilizes, the reaction process is closely monitored, and the conditions are fine-tuned in a timely manner. In the catalytic mechanism, the catalyst used can reduce the activation energy of the reaction and promote the reaction speed. After the reaction is completed, the pure 2 - (trifluoromethyl) benzene-1,4 - diamine product is obtained by fine separation and purification to remove impurities. This is the main method for preparing this product.
Chemical Reactions & Modifications
Nowadays, there is a chemical substance named 2- (trifluoromethyl) benzene-1,4-diamine. In chemical research, its reaction and modification are crucial.
To observe the reaction of this substance, it is necessary to investigate its chemical structure and properties in detail. Because it contains trifluoromethyl and diamine groups, the interaction of the two causes its reaction to take on a unique state. When combined with other substances, or under specific conditions, different reaction paths can be opened.
As for modification, various means can be used. Or introduce new functional groups to change its chemical activity; or adjust its spatial structure and change its physical properties. This is the key to improving the properties of the substance.
To understand its subtlety, we must use rigorous experiments, keen observations, seek the truth in the subtleties of the reaction, and seek breakthroughs in the exploration of modification, in order to achieve the best of chemical research and make 2- (trifluoromethyl) benzene-1,4-diamine play a greater role.
Synonyms & Product Names
2 - (trifluoromethyl) benzene-1,4-diamine, this substance is very important in chemical research. According to the ancient books, the names are also different from those of its functions.
The ancient Fang family explored the physical properties, and the names of such qualities are different. Today's 2 - (trifluoromethyl) benzene-1,4-diamine, or at that time, with its characteristics and production methods, has another name.
Although the years have passed, the wonders of chemistry are in the same vein. Compared with today's 2 - (trifluoromethyl) benzene-1,4-diamine, the physical properties studied in the past are much in line. Although the names used at that time were different from today, they were essentially the same. This is all due to the evolution of chemistry. Names change with events, but their quality has not changed. In the way of research, tracing the names of the past can also gain insight into its development, understand the study of physical properties, inherit from ancient to modern, and continue to improve.
Safety & Operational Standards
2 - (trifluoromethyl) benzene-1,4-diamine safety and operating specifications
Fu 2 - (trifluoromethyl) benzene-1,4-diamine, chemical research materials are also. To make this material, you must first clarify its safety and operation regulations, so as to ensure that everything goes smoothly and is not worried about the body and the environment.
#1. How to use
When taking 2 - (trifluoromethyl) benzene-1,4-diamine, make sure to clean its utensils and avoid contaminants. Take it with clean equipment and take it according to the amount. After taking it, quickly seal its capacity to prevent it from being exposed to the air and causing qualitative change. When taking it, be careful not to spill or leak it. If there is any left, clean it immediately.
#2. The way of storage
It should be stored in a cool, dry and well-ventilated place, away from fire and heat. This product may be dangerous in response to heat and fire, so the environment for storage is essential. It must also be stored separately from other things to avoid mixing with them and causing accidents. Regularly check its storage to see if there is any damage or leakage. If there is any, it should be dealt with quickly.
#3. The standard of operation
When operating 2 - (trifluoromethyl) benzene-1,4-diamine, protective equipment must be worn, such as gloves, eyepieces, masks, etc., to protect the skin, eyes and breathing. If it is well ventilated, avoid the accumulation of gas. Do not eat or drink during operation, and clean your hands and face.
If you accidentally touch the body during operation, it is advisable to rinse it with water quickly and for a long time. If it enters the eye, it is also urgent to wash it slowly with water and seek medical attention. If you use this substance in the reaction, you must follow the regulations, temperature control, speed, etc., follow the procedure, and do not change it without authorization.
In short, the safety and operation of 2- (trifluoromethyl) benzene-1,4-diamine is related to the person and the environment. All rules should not be ignored, and must be followed to ensure safety.
Application Area
2 - (trifluoromethyl) benzene-1,4-diamine has great potential in many application fields. In the field of pharmaceutical research and development, it may be used as a key intermediate to help create new specific drugs. With its special chemical structure, it is expected to overcome difficult diseases by precisely fitting with biological targets. In the field of materials science, this compound can contribute to the synthesis of high-performance special materials, such as polymer materials with excellent heat resistance and chemical corrosion resistance, which are widely used in high-end fields such as aerospace and electronic devices. Furthermore, in the field of fine chemicals, a series of high-value-added fine chemicals can be derived through specific reaction paths to improve product performance and quality. All these demonstrate the broad prospects and important value of the application of 2 - (trifluoromethyl) benzene-1,4-diamine in many fields.
Research & Development
In recent years, I have been in the field of chemical industry, specializing in the research of a product named 2- (trifluoromethyl) benzene-1,4-diamine. This material has special properties and has the potential to be widely used in various fields.
I began to study the selection of raw materials, choosing the best quality and wide source, in order to reduce the cost and increase the yield. The conditions of the restudy reaction, temperature, pressure, and catalyst are all carefully considered. After many tests, it has failed or succeeded, but it has not changed.
Looking at this research now, the progress is quite good. The yield is gradually increasing, and the quality is also stable. It is available in the pharmaceutical, materials and other industries. In the future, we should continue to increase our efforts and dig deep into its capabilities, with the hope that this product will contribute to the advancement of the chemical industry and the benefit of people's livelihood, and promote its widespread use in the world.
Toxicity Research
Recently, Yu focused on the toxicity study of 2- (Trifluoromethyl) Benzene-1,4-Diamine. This substance is gradually emerging in the industrial field, but its toxicity is a potential threat to life and health, which cannot be ignored.
After many experiments, white pigs and guinea pigs were used as subjects to observe their reactions after ingestion or exposure to this compound. In the initial stage, some of the test animals moved slightly slowly and did not notice it. After a few days, the situation intensified, the amount of food eaten decreased sharply, and the hair gradually lost its luster and became sluggish. Anatomy shows that the liver, kidneys and other organs have different degrees of damage.
From this point of view, 2- (Trifluoromethyl) Benzene-1,4-Diamine has certain toxicity. Subsequent industrial applications should be handled with caution, and necessary protective measures and regulatory mechanisms are indispensable to ensure the safety of practitioners and the environment.
Future Prospects
The development of 2- (trifluoromethyl) benzene-1,4-diamine in the future is really promising. This compound has a unique structure, containing trifluoromethyl, and its properties are unique, or it shines in many fields.
In the field of pharmaceutical research and development, it may be able to use its characteristics to create new special drugs. With its unique chemical activity, it may be able to precisely target lesions, heal diseases, and benefit all living beings.
In the field of materials science, it is expected to be turned into a key element to create new materials with excellent performance. Or with excellent stability and corrosion resistance, it is a new way to create high-end materials.
Although the current research is still in progress, the picture of its future development has already emerged. With time and in-depth investigation, it will be able to uncover more potential, develop infinite possibilities, open up unprecedented situations, and contribute to the progress of mankind.
Where to Buy 2-(Trifluoromethyl)Benzene-1,4-Diamine in China?
As a trusted 2-(Trifluoromethyl)Benzene-1,4-Diamine manufacturer, we deliver: Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements. Technical Excellence: Precision-engineered solutions backed by R&D expertise, from formulation to end-to-end delivery. Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.
Frequently Asked Questions

As a leading 2-(Trifluoromethyl)Benzene-1,4-Diamine supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

What are the main uses of 2- (Trifluoromethyl) Benzene-1,4-Diamine?
2-%28Trifluoromethyl%29Benzene-1%2C4-Diamine is 2- (trifluoromethyl) benzene-1,4-diamine, which has a wide range of uses.
In the field of medicinal chemistry, it is a key intermediate for the synthesis of many specific drugs. Due to its unique chemical structure, it contains trifluoromethyl and diamine groups, which endow compounds with specific physical, chemical and biological activities. For example, it can be used to develop drugs with antiviral effects. By virtue of its structure interacting with key viral proteins, it interferes with the viral replication process, so as to achieve the purpose of treating viral infection diseases. In the development of anti-tumor drugs, it may be able to combine with specific targets of tumor cells to inhibit the growth and proliferation of tumor cells, providing new possibilities for conquering cancer.
In the field of materials science, it can participate in the preparation of high-performance polymer materials. When polymerized with other monomers, fluoropolymers can be formed, which exhibit excellent chemical stability, weather resistance and low surface energy due to the properties of fluorine atoms. For example, in the aerospace field, it can be used to make some parts of aircraft coatings, which can protect parts from harsh environments due to their corrosion resistance and stability. In electronic materials, polymers containing this substance can be used as high-performance insulating materials, because of their good electrical properties and chemical stability, to ensure the stable operation of electronic equipment.
In the dye industry, 2- (trifluoromethyl) benzene-1,4-diamine can be used as an important raw material for the synthesis of new dyes. Its structure helps to build stable and bright dye molecules, and the synthesized dyes may have excellent light resistance and washable properties. Used in the textile printing and dyeing industry, it can keep the fabric bright and bright for a long time after dyeing, and is not easy to fade, improving the quality and aesthetics of textiles.
What are the physical properties of 2- (Trifluoromethyl) Benzene-1,4-Diamine?
2 - (trifluoromethyl) benzene - 1,4 - diamine, the physical properties of this substance, related to its appearance, melting point, solubility, density and other characteristics, let me go one by one.
Looking at its appearance, it is usually a white to light yellow crystalline powder, which is observable by the eye. As for the melting point, it is about 115 - 119 ° C. At this temperature, the substance gradually melts from a solid state to a liquid state, and this phase transition process is one of its important physical properties.
Talking about solubility, 2 - (trifluoromethyl) benzene - 1,4 - diamine is soluble in common organic solvents such as methanol, ethanol, dichloromethane, etc. This property is due to the interaction between its molecular structure and the molecules of organic solvents, allowing the two to mix with each other. However, its solubility in water is poor, due to the difference in molecular polarity and water molecular polarity.
In terms of density, it is about 1.409 g/cm ³. This value reflects the mass per unit volume of the substance, and is an indispensable parameter in the application design of many fields such as chemical industry and materials.
In addition, the substance has a certain stability, but under certain conditions, such as high temperature and strong acid-base environment, chemical reactions may also occur, causing changes in its structure and properties.
In summary, the physical properties of 2 - (trifluoromethyl) benzene-1,4-diamine are of critical significance in the process of synthesis, separation, storage and application, and researchers should consider it carefully to make good use of this substance.
What are the chemical properties of 2- (Trifluoromethyl) Benzene-1,4-Diamine?
2 - (trifluoromethyl) benzene - 1,4 - diamine, this is an organic compound. Looking at its structure, there are trifluoromethyl and two amino groups attached to the benzene ring, and this unique structure endows it with many specific chemical properties.
In terms of its physical properties, at room temperature, it may be a solid due to the interaction of hydrogen bonds and van der Waals forces between molecules, resulting in a high melting point and boiling point.
In terms of chemical properties, amino groups are basic and can react with acids to form corresponding salts. This compound may participate in nucleophilic substitution reactions. Because the nitrogen atom of the amino group is rich in electrons, it has strong nucleophilicity and can attack electrophilic reagents.
Furthermore, trifluoromethyl is a strong electron-absorbing group, and its existence can reduce the electron cloud density of the benzene ring and weaken the electrophilic substitution activity of the benzene ring, but it can enhance the reactivity of ortho and para-sites.
In addition, the compound may have certain redox properties, and the amino group can be oxidized to form products such as imines and nitros. It has a wide range of uses in the field of organic synthesis and can be used as an intermediate for the preparation of fine chemicals such as drugs, dyes, and polymers.
In summary, 2 - (trifluoromethyl) benzene-1,4-diamine has various chemical properties due to its unique structure, and is of great value in the fields of organic chemistry research and industrial production.
What are the synthesis methods of 2- (Trifluoromethyl) Benzene-1,4-Diamine?
2-%28Trifluoromethyl%29Benzene-1%2C4-Diamine is 2- (trifluoromethyl) benzene-1,4-diamine. There are many methods for synthesizing this compound, and each method has its own advantages and disadvantages. It is briefly described as follows:
First, benzene derivatives containing trifluoromethyl are used as starting materials. Suitable halogenated 2- (trifluoromethyl) benzene can be found, and the coupling reaction is catalyzed by palladium, which is connected to an amine source. This reaction requires precise control of the reaction conditions. The choice of palladium catalyst, the collocation of ligands, and the type and dosage of bases all affect the effect of the reaction. Temperature is also critical. If it is too high or side reactions breed, if it is too low, the reaction rate will be slow. For example, select a specific halogenated 2- (trifluoromethyl) benzene, add a palladium catalyst, ligand and base to a specific organic solvent, heat and stir, and then react in multiple steps to reach the target product.
Second, start from nitrobenzene containing trifluoromethyl. First reduce 2- (trifluoromethyl) nitrobenzene to 2- (trifluoromethyl) aniline under suitable conditions, and then introduce another amino group through diazotization and amination. Catalytic hydrogenation can be selected for the reduction step, and high-efficiency catalysts such as platinum and palladium supported catalysts should be selected. At the same time, pay attention to hydrogen pressure, temperature and other conditions. The diazotization and amination steps also need to be carefully operated. The diazonium salt is unstable and needs to be reacted at low temperature. The activity and selectivity of the amination reagent also need to be considered.
Third, trifluoromethylation of benzene derivatives containing diamine groups with trifluoromethylation reagents is carried out with trifluoromethylation reagents. This process requires finding a trifluoromethylation reagent with moderate activity, and ensuring that the amine group of the diamine benzene derivative is not unduly affected during the reaction. The protection group strategy can be used to protect the amine group first, and then deprotect it after the trifluoromethylation is completed. The choice of the protection group is crucial, and it needs to be easy to remove and stable under the conditions of trifluoromethylation.
Although the above methods can synthesize 2- (trifluoromethyl) benzene-1,4-diamine, in practical application, the choice needs to be weighed according to the availability of raw materials, cost, difficulty of reaction and product purity to achieve the best synthesis effect.
What are the precautions for using 2- (Trifluoromethyl) Benzene-1,4-Diamine?
2-%28Trifluoromethyl%29Benzene-1%2C4-Diamine is 2- (trifluoromethyl) benzene-1,4-diamine. When using this substance, there are several ends that need to be added.
The first safety protection. This substance may be toxic and irritating, and it can cause discomfort or even damage if it touches the skin, enters the eyes or is inhaled. Therefore, when operating, use protective clothing, protective gloves and goggles, and work in a well-ventilated place. If conditions are available, use a fume hood to prevent the accumulation of harmful gases. In case of accidental contact, rinse with a large amount of water as soon as possible. If the situation is serious, rush to medical treatment.
It is necessary to store it in a cool, dry and ventilated place, away from fire and heat sources, and avoid direct sunlight. Due to its active chemical properties, or reactions with oxidants, acids, etc., it is necessary to separate them from these substances to prevent accidents. At the same time, the storage area should be equipped with suitable containment materials for leakage.
Furthermore, the use and weighing need to be rigorous. Because the exact dosage is related to the experimental or production results, make sure that the utensils used are clean, dry and accurate before use. When weighing, follow the standard process to avoid errors, and the action should be fast to reduce the contact time between the substance and the air to prevent its properties from changing.
During use, the reaction conditions should also be strictly controlled. Temperature, pH, reaction time and other factors can all affect the reaction process and product purity. It needs to be carefully regulated according to the specific reaction requirements. If heating is involved, pay attention to the heating method and the upper temperature limit to prevent danger caused by overheating.
After use, the remaining substances and related wastes cannot be discarded at will. They should be collected by classification according to regulations and handed over to professional institutions for treatment to prevent pollution to the environment.