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2-(Trifluoromethyl)-4-Fluoro Nitrobenzene

2-(Trifluoromethyl)-4-Fluoro Nitrobenzene

Hongda Chemical

    Specifications

    HS Code

    981447

    Chemical Formula C7H3F4NO2
    Molecular Weight 209.1
    Appearance Typically a liquid
    Boiling Point Around 185 - 187 °C
    Density Approx. 1.5 g/cm³
    Solubility Poorly soluble in water, soluble in organic solvents
    Vapor Pressure Low at room temperature
    Flash Point Relatively high, around 77 °C
    Stability Stable under normal conditions, but reactive with strong oxidants

    As an accredited 2-(Trifluoromethyl)-4-Fluoro Nitrobenzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing 500g of 2-(trifluoromethyl)-4-fluoro nitrobenzene packaged in a sealed, chemical - resistant bottle.
    Storage 2-(Trifluoromethyl)-4-fluoro nitrobenzene should be stored in a cool, dry, well - ventilated area, away from heat sources and ignition points. Keep it in a tightly closed container, preferably made of corrosion - resistant materials due to its chemical nature. Store it separately from oxidizing agents and reducing substances to prevent potential reactions.
    Shipping 2-(Trifluoromethyl)-4 -fluoro nitrobenzene is shipped in specialized, leak - proof containers. It follows strict regulations due to its chemical nature. Shipment ensures proper packaging to prevent damage and spillage during transit.
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    2-(Trifluoromethyl)-4-Fluoro Nitrobenzene 2-(Trifluoromethyl)-4-Fluoro Nitrobenzene
    General Information
    Historical Development
    "Remembering the Past of (2- (Trifluoromethyl) -4 -Fluoronitrobenzene) "
    Taste the industry of chemical industry, there is a name (2- (Trifluoromethyl) -4 -Fluoronitrobenzene). It is also the beginning, and all the sages have devoted themselves to trying to understand its properties and explore its uses.
    At the beginning, researchers were in the dark room, using subtle materials, trying all kinds of methods to obtain this thing. Although there are many mistakes, they are determined to persevere.
    As the years go by, the masters gradually understand the technique of making it, its quality is wonderful. Or used for the production of medicinal stones, or to help the renewal of materials. Therefore, in the field of chemical industry, this thing gradually became more and more important, which was needed by various industries, and its merits were also written in the current world. People in future generations should inherit the ambitions of the previous sages and carry on the past and open up the future, so that the use of this thing can be beneficial to the wider and better.
    Product Overview
    Today there is a product called 2- (trifluoromethyl) -4-fluoronitrobenzene. This is a key raw material for organic synthesis and has extraordinary uses in the fields of medicine, pesticides and materials science.
    Looking at its shape, it is mostly a colorless to light yellow liquid at room temperature, with a unique smell. Its activity can be used as an active intermediate in many chemical reactions. Because its molecular structure contains trifluoromethyl and fluorine atoms, it is endowed with unique physical and chemical properties. Trifluoromethyl has strong electron absorption, which can change the electron cloud distribution of compounds, improve their stability and fat solubility; the introduction of fluorine atoms also significantly affects the reactivity and biological activity of compounds.
    Preparation of this product is carefully prepared by the organic synthesis path specified by Chang Wright through multi-step reaction. However, the preparation process requires strict compliance with operating procedures and attention to safety matters, because some raw materials may be toxic and corrosive.
    2- (trifluoromethyl) -4-fluoronitrobenzene, which is important in the chemical industry, is the cornerstone of many cutting-edge research and innovative applications, and promotes the vigorous development of related industries.
    Physical & Chemical Properties
    2- (trifluoromethyl) -4 -fluoronitrobenzene is an important substance for chemical research. Its physical properties, in terms of normal temperature, are colorless to light yellow liquid with unique odor. Its boiling point is quite high, about a certain temperature range, which makes it require specific conditions for separation and purification.
    Discussing chemical properties, because it contains functional groups such as fluorine, nitro and trifluoromethyl, its chemical activity is prominent. Nitro has strong electron absorption, which reduces the electron cloud density of the benzene ring and increases the difficulty of electrophilic substitution reactions; fluorine atoms have high electronegativity, which affects the electron cloud distribution of molecules and enhances the stability of compounds. The existence of trifluoromethyl greatly enhances the fat solubility of this substance, and has great potential for application in the fields of organic synthesis and medicinal chemistry. The physicochemical properties of this substance lay the foundation for in-depth research in related fields.
    Technical Specifications & Labeling
    Today there is a product named 2- (trifluoromethyl) -4-fluoronitrobenzene. Its preparation method needs to follow certain technical specifications and standards. To make this product, when the ratio of its materials is clear in advance, all the materials used need to be accurately weighed. When reacting, in a suitable container, control the appropriate temperature, pressure and time. Looking at the material, it should be pure and free of impurities to ensure the quality of the product.
    After making it, it needs to be tested in detail according to the parameters of the product. Measure its purity without the slightest deviation; looking at its properties, it should conform to the established rules. If there is any discrepancy, it is necessary to carefully check the reason and adjust it. In this way, the product can meet the requirements of technical specifications and labeling (commodity parameters) for use where required.
    Preparation Method
    The method of making 2 - (trifluoromethyl) - 4 - fluoronitrobenzene is related to the raw materials and production process, reaction steps and catalytic mechanism. The raw materials need to be carefully selected, such as selecting a specific halogenated aromatic hydrocarbon, with a reagent containing trifluoromethyl and fluorine. At the beginning of the reaction, with the help of a suitable temperature and a catalyst, the halogenated aromatic hydrocarbon is fused with the reagent containing trifluoromethyl. This step requires precise temperature control to promote the smooth substitution reaction. Then, the fluorine reagent is added, and after another round of reaction, the fluorine atom is just in the predetermined position. The catalyst used needs to be highly active and selective to improve the yield and purity. Between each reaction step, fine separation and purification are appropriate to remove impurities. Thus, high purity 2 - (trifluoromethyl) - 4 - fluoronitrobenzene was obtained.
    Chemical Reactions & Modifications
    Nowadays, there are chemical substances called 2- (trifluoromethyl) -4-fluoronitrobenzene. It is crucial for chemical reactions and modifications.
    Past studies have shown that this compound can undergo many wonderful changes under specific reaction conditions. The structure of fluorine and trifluoromethyl affects the distribution of its electron cloud, resulting in unique reactivity. In case of nucleophiles, it often reacts at specific positions in the benzene ring to form new derivatives.
    However, there are many difficulties in improving its properties. Due to the complex steric resistance and electronic effects of the substituents, it is not easy to regulate the reaction direction and product selectivity. Although the reaction process can be adjusted slightly by changing the reaction temperature, solvent, catalyst type and dosage, it is still necessary for chemists to repeatedly study and explore in order to clarify its chemical essence and expand its application.
    Synonyms & Product Names
    2024 is the era of rapid development of organofluorine chemistry, and I have been focusing on the research of fluorine-containing nitrobenzene compounds for a long time. Today there is a thing called 2- (trifluoromethyl) -4-fluoronitrobenzene, which has extraordinary uses in many fields.
    This 2- (trifluoromethyl) -4-fluoronitrobenzene, also known as Yizhong. Or 4-fluoro-2- (trifluoromethyl) nitrobenzene, which is named after its atomic arrangement and structural characteristics. Its trade name, also known as [specific trade name, because no more information is temporarily missing], is circulated in the chemical market under this name and is well known to all industry players.
    This compound has unique properties and high reactivity. It can be used as a key intermediate in the synthesis of medicine to help create new special drugs. In the field of materials science, it can also contribute to the development of high-performance materials. I often think that if we can deeply explore its mysteries and optimize the preparation method, it will definitely make it better serve the world and contribute to human well-being.
    Safety & Operational Standards
    2 - (trifluoromethyl) -4 -fluoronitrobenzene safety and operating specifications
    Fu 2 - (trifluoromethyl) -4 -fluoronitrobenzene, a common compound in chemical preparation. Its properties are special, related to safety and operation, and should not be careless.
    At the storage end, it is appropriate to choose a cool, dry and well-ventilated place. This product is prone to danger when exposed to heat, open flames or oxidants, so it must be kept away from all heat sources and fires. And should be separated from oxidants and food chemicals, and must not be mixed in storage to prevent interaction and cause accidents.
    When it comes to operation, operators must wear appropriate protective equipment. Protective clothing, gloves, and goggles are all essential to prevent contact with human skin and eyes. In the operating room, ventilation must be smooth to prevent gas accumulation.
    If it unfortunately touches the skin, it should be quickly rinsed with a large amount of flowing water, followed by medical treatment. If it enters the eye, it should also be immediately rinsed with flowing water or normal saline, and quickly seek medical assistance.
    Furthermore, during use, accurate weighing and access are extremely important. It must not be used in excess, causing the reaction to get out of control. The control of reaction conditions should not be ignored, and parameters such as temperature and pressure must be strictly regulated in accordance with established procedures.
    When disposing of, it must also be in accordance with relevant regulations. Do not dump at will, when handed over to a professional organization, handle it in a proper manner to protect the environment.
    In short, the safety and operation specifications of 2- (trifluoromethyl) -4 -fluoronitrobenzene are the basis for ensuring personnel safety, environmental safety and smooth experimentation, and must not be slack. Operators should be well aware of the principles and abide by the procedures to avoid danger.
    Application Area
    2- (trifluoromethyl) -4-fluoronitrobenzene is also an organic compound. Its application field is quite wide. In the field of medicinal chemistry, it can be a key intermediary. With its special structure, it can participate in a variety of reactions and help synthesize drug molecules with unique pharmacological activities.
    In materials science, it also has potential applications. It can be chemically modified to introduce polymer materials to improve their properties, such as enhancing the stability and weather resistance of materials.
    In the field of pesticide chemistry, it can be used as a raw material for synthesizing new pesticides. Because of its structural characteristics, it may give pesticides better insecticidal and bactericidal effects, and the impact on the environment is controllable. Due to its unique properties, this compound has shown important value in various fields, opening up many possibilities for scientific research and industrial production.
    Research & Development
    There is a substance today, named 2- (trifluoromethyl) -4-fluoronitrobenzene. I am a chemical researcher, and I am concerned about its research.
    This compound has unique properties, and its structure is exquisite. It contains trifluoromethyl, fluorine and nitro groups. To explore the method of its synthesis, it is necessary to check the reaction conditions and the proportion of raw materials. Optimize the process to improve the yield and purity.
    Its application prospects are wide, in the field of medicine, or as a key raw material for the creation of new pharmaceuticals; in materials science, it can be the cornerstone of the research and development of special performance materials.
    We should study it diligently, use scientific methods to explore its mysteries, and promote its development, so that this compound can enhance the well-being of mankind. We will move forward steadily and unremittingly on the road of scientific research.
    Toxicity Research
    Nowadays, there are chemical substances, named 2- (trifluoromethyl) -4-fluoronitrobenzene, and we focus on toxicological research. This substance has a special structure, composed of trifluoromethyl, fluorine atoms and nitro groups. The study of its toxicity is related to the well-being of all living beings and cannot be ignored.
    After testing, this substance may disturb the physiological functions of living beings. At the cellular level, or affect its metabolism and division process. Ingestion by organisms may damage organs such as liver, kidneys, etc. And its toxicity may accumulate along the food chain, endangering the ecology.
    However, to clarify its details, extensive research is needed. Multiple methods are applied to explore the path of toxicology and the degree of harm. The theory of certainty of period provides evidence for protection and governance, ensuring the safety of all living beings and the balance of ecology.
    Future Prospects
    In the future, it is especially important for chemical substances. Today, there is 2- (trifluoromethyl) -4-fluoronitrobenzene, and its unseen future can be seen.
    This compound has unique properties and is exquisite, and it is expected to be greatly improved in many fields. In the field of research and development, it may be possible to use new foundations and their characteristics to help overcome problems. In the field of material science, it may also be able to spawn novel materials to meet the needs of various industries.
    As science and technology continue to evolve, the power of research is not good. In time, we will be able to better understand its properties and make good use of its capabilities. The function of 2- (trifluoromethyl) -4-fluoronitrobenzene is to improve the well-being of the world, to increase the amount of work, and this is not yet possible.
    Where to Buy 2-(Trifluoromethyl)-4-Fluoro Nitrobenzene in China?
    As a trusted 2-(Trifluoromethyl)-4-Fluoro Nitrobenzene manufacturer, we deliver: Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements. Technical Excellence: Precision-engineered solutions backed by R&D expertise, from formulation to end-to-end delivery. Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.
    Frequently Asked Questions

    As a leading 2-(Trifluoromethyl)-4-Fluoro Nitrobenzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

    What are the main uses of 2- (Trifluoromethyl) -4-Fluoro Nitrobenzene?
    2 - (trifluoromethyl) - 4 - fluoronitrobenzene, this substance has a wide range of uses and is often a key raw material in chemical synthesis.
    From the perspective of the field of pharmaceutical creation, its importance is highlighted. Due to its unique chemical structure, it can introduce specific functional groups into drug molecules, thereby improving the physical and chemical properties of drugs, such as lipophilicity and stability. With its fluorine-containing and trifluoromethyl properties, it can enhance the binding force between drugs and targets and enhance the efficacy of drugs. Therefore, it has many applications in the process of new drug development, which is of great help.
    In the field of materials science, it is also indispensable. With it as a starting material, through a specific reaction path, polymer materials with special properties can be synthesized. The resulting materials, either with excellent corrosion resistance or good thermal stability, have great potential in aerospace, electronic information and other fields that require strict material properties, and can meet the needs of special environments.
    Furthermore, in the preparation of fine chemical products, it is also commonly used. It can participate in many organic reactions, and through ingenious design and synthesis, it can be converted into various fine chemicals, such as high-performance dyes, functional additives, etc., which contribute to the development of the fine chemical industry and promote the continuous innovation and progress of this field.
    In summary, 2 - (trifluoromethyl) - 4 - fluoronitrobenzene plays an important role in many branches of the chemical industry and plays a key role in promoting the development of various industries.
    What are the physical properties of 2- (Trifluoromethyl) -4-Fluoro Nitrobenzene
    2 - (trifluoromethyl) - 4 - fluoronitrobenzene, an organic compound, is widely used in the chemical industry. Its physical properties are unique, with the following characteristics:
    - ** Appearance and Properties **: Under normal conditions, it is mostly colorless to light yellow liquid, with a clear and transparent texture. Looking at it, it is no different from ordinary colorless liquids, but it contains a special chemical structure, giving it a unique chemical activity.
    - ** Odor **: Emissions a special aromatic odor, although not pungent, it has a unique recognition. This odor is derived from the interaction of benzene rings and substituents in the molecular structure, and can be used as a distinguishing sign in specific environments.
    - ** Melting point and boiling point **: The melting point is about -27 ° C, and the boiling point is about 184-186 ° C. The melting point is low, resulting in a liquid state at room temperature and pressure; the boiling point indicates that it needs to reach a certain temperature before it can be converted from liquid to gaseous state. This property is of great significance in separation, purification and control of reaction conditions.
    - ** Density **: The density is about 1.52 g/cm ³, which is heavier than water. When it comes to liquid-liquid separation operations, the substance will sink to the bottom of the water, providing an important basis for practical chemical operations.
    - ** Solubility **: Slightly soluble in water, but can be well miscible with most organic solvents, such as ethanol, ether, acetone, etc. This solubility is due to the difference between its molecular polarity and that of water molecules, as well as the principle of similar miscibility with organic solvent molecules, and is widely used in organic synthesis reactions and extraction and separation.
    - ** Volatility **: It has a certain degree of volatility, and some molecules will escape into the air at room temperature. When using, pay attention to ventilation conditions to ensure the safety of the operating environment and prevent health damage caused by inhalation of this substance vapor.
    What are the synthesis methods of 2- (Trifluoromethyl) -4-Fluoro Nitrobenzene
    There are many ways to synthesize 2 - (trifluoromethyl) - 4 - fluoronitrobenzene. The following are the common methods:
    First, the method of initiating the halogenation reaction. The benzene derivative containing (trifluoromethyl) is used as the starting material, and the fluorine atom is first introduced through the halogenation reaction. If a suitable halogenating reagent is selected, under suitable reaction conditions, a fluorination reaction occurs at a specific position in the benzene ring. Among these, the control of reaction conditions is the key, such as temperature, catalyst selection and dosage. If the temperature is too high or side reactions are frequent, if it is too low, the reaction rate will be delayed. The activity and selectivity of the halogenating reagent used also deeply affect the purity and yield of the product.
    Second, the method of subsequent modification of nitrogenation. First, nitrogenation of the benzene ring is carried out, and nitro groups are introduced. Then, under specific conditions, other positions of the benzene ring are (trifluoromethyl) and fluorinated. During the nitrogenation reaction, attention should be paid to the position and amount of nitro groups introduced, which is related to the difficulty of the subsequent reaction and the structure of the product. The (trifluoromethyl) and fluorination steps also require precise regulation of the reaction conditions. The (trifluoromethyl) reagents and fluorination reagents used have their own unique reactivity and requirements.
    Third, it is constructed by coupling reaction. Using different organic fragments containing fluorine, (trifluoromethyl) and nitro groups, by coupling reaction, they are connected to form the target product. Coupling reactions often require specific catalysts and ligands to promote the reaction. Different types of coupling reactions, such as Suzuki coupling, Stille coupling, etc., have their own scope of application and advantages. When selecting an appropriate coupling reaction, many factors such as the structure of the starting material, the difficulty of the reaction conditions, and the separation and purification of the product need to be considered.
    All these methods have advantages and disadvantages. In the actual synthesis, when considering the availability of starting materials, the feasibility of the reaction conditions, the purity and yield requirements of the product, etc., the optimal synthesis path is selected to achieve the purpose of efficient preparation of 2 - (trifluoromethyl) -4 -fluoronitrobenzene.
    What are the precautions for 2- (Trifluoromethyl) -4-Fluoro Nitrobenzene during storage and transportation?
    2-%28Trifluoromethyl%29-4-Fluoro+Nitrobenzene is 2- (trifluoromethyl) -4 -fluoronitrobenzene. When storing and transporting this substance, pay attention to many matters.
    Its properties are dangerous chemicals, toxic and irritating. When storing, the first environment is selected. It should be placed in a cool and ventilated warehouse, away from fire and heat sources, to prevent the temperature from rising and causing changes in its chemical properties and causing danger. And the temperature and humidity of the warehouse should be strictly controlled. Usually, the temperature should be maintained in a specific range, and the humidity should not be too high to avoid damage to its quality or chemical reactions due to moisture.
    Furthermore, storage must follow the principle of isolation. Do not mix with oxidizing agents, reducing agents, alkalis, etc. Because of its active chemical properties, contact with the above substances is prone to violent reactions, and even explosions. Storage containers are also very critical, be sure to choose suitable materials to ensure good sealing and prevent leakage.
    During transportation, safety is also a top priority. Transport vehicles must have corresponding qualifications and protective equipment, and escorts should be familiar with their characteristics and emergency disposal methods. The handling process should be light and light, and it is strictly forbidden to drop and heavy pressure to prevent the container from breaking. During transportation, you should also follow the specified route to avoid densely populated areas and important facilities. In case of leakage, effective measures can be taken quickly to reduce hazards.
    In short, the storage and transportation of 2 - (trifluoromethyl) -4 - fluoronitrobenzene is related to personnel safety and environmental safety, and all links must be operated in strict accordance with regulations and treated with caution to ensure safety.
    What is the market price of 2- (Trifluoromethyl) -4-Fluoro Nitrobenzene?
    2-%28Trifluoromethyl%29-4-Fluoro+Nitrobenzene, that is, 2 - (trifluoromethyl) -4 -fluoronitrobenzene, the market price often changes for a variety of reasons.
    The first to bear the brunt, and the price of raw materials for the preparation of this compound has a significant impact. If the price of various starting materials required for preparation rises, such as specific fluorine-containing and trifluoromethyl-containing basic raw materials, or the price of various reagents used in the reaction process rises, it will undoubtedly lead to an increase in production costs, which in turn drives up product prices. Conversely, if the supply of raw materials is sufficient, the price is stable or decreases, and the product price may also decrease accordingly.
    Furthermore, differences in production processes have a significant impact on costs and prices. Advanced and efficient production processes can improve the output efficiency of products, reduce energy consumption, and reduce the occurrence of side reactions, thus effectively controlling costs. If a company develops a more optimized synthesis route to produce high-quality 2- (trifluoromethyl) -4 -fluoronitrobenzene at a lower cost, then its pricing may be more advantageous in the market competition.
    Market supply and demand conditions are also key factors. If this compound is in high demand in many fields, such as medicine, pesticides, materials, etc., but the number of producers is limited and the supply is difficult to meet the demand, its price will inevitably rise. On the contrary, if the market demand is weak, and there are many production enterprises and excess capacity, enterprises may lower prices to promote sales in order to compete for market share.
    In addition, the macroeconomic situation, policies and regulations, and transportation costs will also have an impact on their market prices. The economic situation is improving and the industry is developing rapidly, which may drive demand growth and affect prices. As environmental protection policies become stricter, enterprises will increase environmental protection investment in order to meet environmental protection requirements, which will also increase costs and affect prices. Changes in transportation costs due to factors such as oil price fluctuations and transportation distances will also affect the final market price. Therefore, the market price of 2 - (trifluoromethyl) -4 -fluoronitrobenzene is in a dynamic state, and it is difficult to give a fixed value. Therefore, it is necessary to consider the above factors comprehensively.