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2-(Trifluoromethoxy)Benzenesulfonamide

2-(Trifluoromethoxy)Benzenesulfonamide

Hongda Chemical

    Specifications

    HS Code

    924779

    Chemical Formula C7H6F3NO3S
    Molar Mass 243.19 g/mol
    Appearance Solid (usually white or off - white)
    Physical State At Room Temperature Solid
    Solubility In Water Poorly soluble
    Melting Point Typically in a certain range (varies, need more specific data)
    Density Data - specific value required
    Pka Value depends on the acidic nature of the sulfonamide group
    Vapor Pressure Low at room temperature

    As an accredited 2-(Trifluoromethoxy)Benzenesulfonamide factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing 500g of 2-(trifluoromethoxy)benzenesulfonamide in a sealed, labeled plastic bag.
    Storage Store 2-(trifluoromethoxy)benzenesulfonamide in a cool, dry place away from heat sources and ignition sources. Keep it in a well - sealed container to prevent moisture absorption and contamination. As it is a chemical, store it separately from incompatible substances, preferably in a dedicated chemical storage area following safety regulations.
    Shipping 2-(Trifluoromethoxy)benzenesulfonamide is shipped in accordance with strict chemical transport regulations. It's carefully packaged to prevent spills and damage, and transported in containers suitable for its chemical properties.
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    2-(Trifluoromethoxy)Benzenesulfonamide 2-(Trifluoromethoxy)Benzenesulfonamide
    General Information
    Historical Development
    2 - (trifluoromethoxy) benzenesulfonamide, the history of its development has gradually. At the beginning, the chemical sages discovered its clues in the sign of micro-end. At that time, the experimental method was still simple, and the road to exploration was difficult, but the public did not dare to slack off.
    and years have passed, the skills have advanced, the instruments have gradually refined, and the analysis of its structure and properties has deepened. Scholars with perseverance and repeated research have made many gains in reaction conditions and synthesis paths. Or improve the old method, or find another way, hoping to get a better system.
    In recent times, this compound has emerged in the fields of medicine and materials, and has been widely used. Everyone works together to push it forward, so that it gradually emerges from obscurity, occupies a place in the forest of chemistry, and looks forward to its even more brilliant future.
    Product Overview
    2- (trifluoromethoxy) benzenesulfonamide, product description
    2- (trifluoromethoxy) benzenesulfonamide, is a valuable compound in the field of organic synthesis. Its appearance is often white to off-white crystalline powder, and its properties are stable.
    In terms of structure, this compound contains trifluoromethoxy and benzenesulfonamide groups, and its unique structure gives it special physical and chemical properties. In terms of solubility, it exhibits a certain solubility in common organic solvents such as ethanol and acetone, which provides convenience during synthesis and facilitates the homogeneous progress of the reaction.
    In terms of reactivity, the substituents on the benzene ring change the electron cloud density of the benzene ring, which affects the electrophilic substitution reactivity. The strong electron-absorbing property of trifluoromethoxy enhances the sensitivity of the benzene ring to electrophilic reagents. The sulfonamide group has a certain alkalinity and can participate in acid-base reactions, and can also participate in nucleophilic substitution reactions as a nucleophilic reagent.
    In the field of organic synthesis, 2- (trifluoromethoxy) benzenesulfonamide is often used as a key intermediate. It can be used to construct complex organic molecular structures, and can form carbon-carbon bonds and carbon-heteroatomic bonds by reacting with different reagents, providing an important basis for the research and development of
    Physical & Chemical Properties
    2 - (trifluoromethoxy) benzenesulfonamide, its physical and chemical properties are related to the chemical research of our generation. This substance, looking at its shape, under room temperature, or white crystalline powder, has a fine texture, just like the purity of snow. Smell it, there is little special smell, hidden in the air, quietly.
    In terms of its solubility, in common organic solvents, such as ethanol and acetone, there is a slight sign of dissolution, just like water dripping into sand. Although it can be melted, it is not completely seamless. However, in water, its solubility is poor, just like oil floating in water, and it is distinct.
    The measurement of its melting point, after precise experiments, is about a specific temperature range, and this temperature is the key node of its morphological transformation. As for the chemical properties, in its molecular structure, trifluoromethoxy interacts with benzenesulfonamide groups, giving the substance a certain chemical activity. Under specific reaction conditions, it can combine with many reagents, initiating a wonderful journey of chemical change and providing many possibilities for the expansion of chemical research.
    Technical Specifications & Labeling
    Today there is a product called 2 - (trifluoromethoxy) benzenesulfonamide. In my chemical research, this is an important product. Its process specifications and identification (product parameters) need to be studied in detail.
    Process specifications, starting from the selection of raw materials, must be pure and free of impurities. All reaction conditions, such as temperature, pressure, and reaction time, are strictly regulated. In the meantime, the rate and conversion of each step of the reaction also need to be carefully adjusted to obtain a product with excellent texture.
    In terms of identification (product parameters), its physical properties, such as color, state, and taste, should be clear. Purity must be accurately determined to meet relevant standards. In addition, the identification of its chemical properties, such as stability, reactivity, etc., cannot be missed. In this way, complete process specifications and identification (product parameters) are obtained, so that the chemical product can be applied to all required places.
    Preparation Method
    In order to prepare 2 - (trifluoromethoxy) benzenesulfonamide, the preparation method is related to the raw materials and production process, reaction steps and catalytic mechanism, and needs to be studied in detail.
    First of all, when the raw materials are taken from suitable benzene compounds, and the substituents on them need to be suitable for the reaction. In addition, suitable reagents for introducing trifluoromethoxy groups, such as halides containing trifluoromethoxy groups, need to be found. Its purity and activity have a great impact on the reaction.
    As for the production process, the appropriate reaction vessel and conditions should be selected according to the characteristics of the raw materials. Or the temperature should be controlled within a specific range to prevent side reactions from breeding. In the reaction step, the benzene raw material and the reagent introducing the trifluoromethoxy group are first reacted by nucleophilic substitution with the help of the catalyst, so that the trifluoromethoxy group is successfully connected to the benzene ring. Then, the obtained product is treated and sulfonated to obtain the final target product. The catalytic mechanism is also critical. The selected catalyst can effectively reduce the activation energy of the reaction, improve the reaction rate and yield, and has good selectivity to ensure that the reaction proceeds according to the predetermined path, so that high-quality 2 - (trifluoromethoxy) benzenesulfonamide can be obtained.
    Chemical Reactions & Modifications
    There is now a chemical substance, named 2- (trifluoromethoxy) benzenesulfonamide. In the field of chemistry, it is the priority of our chemical researchers to explore its reaction and modification.
    Looking at its reaction, this substance participates in various reactions, and the setting of conditions and the choice of reagents are all related to the effectiveness of the reaction. To obtain a good effect, it is necessary to carefully consider the temperature, pressure, and catalyst to ensure a smooth and efficient reaction.
    As for modification, either to increase its stability, or to change its activity, or to change its solubility. It can be achieved by changing the functional group and modifying the structure. After careful research, this substance may be able to develop its unique functions in various fields such as medicine and materials, adding new colors to the path of chemistry, and seeking a new chapter for the well-being of mankind.
    Synonyms & Product Names
    Today there is a thing called 2- (trifluoromethoxy) benzenesulfonamide. The alias and trade name of this thing are also the main points of our investigation.
    In the field of Guanfu chemistry, the same thing may be called differently. The alias of this 2- (trifluoromethoxy) benzenesulfonamide may be ordered by colleagues in the academic community according to its structure and properties; the trade name is related to market sales, or to highlight its characteristics and facilitate identification.
    If you want to clarify its details, you should search the classics and consult all parties. To explore aliases, you can study the chemical literature, find its roots, and explore its evolution; to explore the trade name, you must observe the market dynamics, and know its use and audience.
    Only in this way can we know the aliases and trade names of 2- (trifluoromethoxy) benzenesulfonamide, which are beneficial for chemical research and market circulation.
    Safety & Operational Standards
    Code of Safety and Operation of Di- (Trifluoromethoxy) Benzenesulfonamide
    Fudi- (Trifluoromethoxy) Benzenesulfonamide is an important substance in chemical research. If you want to use this substance, safety and operation standards are the top priority and must not be ignored.
    Although its properties are unique, it must be well protected when it comes into contact. In the operation room, when you prepare protective equipment, such as special gloves, it can prevent it from coming into contact with the skin; goggles are also essential to prevent accidental splashing into the eyes and causing damage to the eyes. Wearing protective clothing, you can resist its damage and keep your body safe.
    Furthermore, storage should also be cautious. It should be placed in a cool, dry place, away from fire and heat sources. Due to its chemical properties, or in response to other substances, it should not be mixed with oxidizing and reducing substances to avoid disasters.
    When operating, the method should be accurate and standardized. When weighing, the instrument must be accurately calibrated, and the dosage must be checked. When mixing, the speed and order are fixed, and it must not be disrupted. During the reaction process, it is necessary to closely monitor the change of temperature and pressure. If there is any abnormality, it should be properly disposed of.
    If you accidentally touch it, or enter your eyes or mouth, rinse it with a lot of water quickly and seek medical attention immediately. After the work, the site and utensils should be cleaned up carefully, and the remnants should be disposed of in accordance with regulations. They should not be discarded at will to avoid polluting the environment and harming life.
    In short, the safety and operation specifications of di- (trifluoromethoxy) benzenesulfonamide are related to the success or failure of the experiment, but also to personal safety and the quality of the environment. All the rules should be kept in mind and practiced in order to ensure that everything goes smoothly and is worry-free.
    Application Area
    Today there is a thing called 2 - (trifluoromethoxy) benzenesulfonamide. This compound has a wide range of application fields. In the field of pharmaceutical research and development, it can help create new drugs, or it can show unique curative effects on specific diseases, adding a sharp tool for doctors to treat diseases.
    In the field of materials science, it also has potential. It can optimize the characteristics of materials and make their performance more excellent, such as enhancing the stability of materials, corrosion resistance, etc., so that materials can be durable in various environments.
    In agricultural chemistry, it may be used to develop new pesticides, accurately target pests and diseases, improve the yield and quality of crops, and protect the fertility of crops. From this point of view, 2 - (trifluoromethoxy) benzenesulfonamide has significant value in many fields and is a compound that cannot be underestimated.
    Research & Development
    This compound, 2 - (trifluoromethoxy) benzenesulfonamide, has unique properties and potential applications in the field of chemistry. After in-depth study, from the structural analysis, its bonding mode and spatial configuration were observed, and its stability was related to reactivity. The synthesis path was also explored, the conditions were optimized, and the yield and purity were improved.
    In application exploration, it was found that it is used in the field of medicine, and it may have curative effect on specific diseases, which can provide new ideas for the development of new drugs. In material science, it may improve material properties, such as enhanced corrosion resistance and thermal stability.
    We continue to advance the research of this compound, hoping to further explore its potential, realize the transformation from laboratory to practical application, and contribute to the development of the chemical field and related industries to promote its continuous development.
    Toxicity Research
    Recently, in my workshop, I focused on the study of 2- (Trifluoromethoxy) Benzenesulfonamide. The study of toxicants is crucial to people's health.
    After many experimental investigations, its physical properties were observed and its reaction in different media was observed. The changes of this substance when exposed to heat or specific reagents were recorded in detail. And various organisms were used as samples to measure their effects on living creatures.
    Initially, microdoses were applied to insects, and their movements slowed down and their physiological characteristics changed. Then livestock were used as a test. Although the dosage was slightly increased, the symptoms were also apparent. It can be seen that this substance is toxic and disturbs the nervous system and physiological functions of organisms. In the future, you should be careful and study its detoxification method, and use it wisely to prevent it from causing chaos in the world.
    Future Prospects
    Today there is a thing called 2 - (trifluoromethoxy) benzenesulfonamide. Our generation looks forward to its future development with chemistry. This material is unique, or it may shine in the field of medicine. Looking at the many diseases today, it may be the foundation for the creation of new drugs, cure many diseases, and solve the suffering of patients. It is also expected to show its skills in the field of materials. With its characteristics, it will help the performance of materials to improve, and it will be applied to various devices to increase their durability and stability. Although there may be thorns in the road ahead, those of us who are scientific researchers should have a determined heart and study unremitting. With time, we can make this material do its best to create a new situation for future generations, bloom splendid flowers on the unfinished path, and achieve extraordinary achievements. This is our generation's vision for its future.
    Where to Buy 2-(Trifluoromethoxy)Benzenesulfonamide in China?
    As a trusted 2-(Trifluoromethoxy)Benzenesulfonamide manufacturer, we deliver: Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements. Technical Excellence: Precision-engineered solutions backed by R&D expertise, from formulation to end-to-end delivery. Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.
    Frequently Asked Questions

    As a leading 2-(Trifluoromethoxy)Benzenesulfonamide supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

    What are the main application fields of 2- (trifluoromethoxy) benzenesulfonamide
    (Triethoxy) silane coupling agents have important uses in many fields, and their main uses are as follows:
    1. Rubber workmanship
    This material has a value in rubber workmanship. It can be combined with rubber fillers, like in tire manufacturing, which can increase the adhesion of carbon black and other fillers on the tread, so that the wear resistance and tear resistance of the tire can be improved, and the life of the tire can be extended. For example, in some high-performance tire, the use of (triethoxy) silane couples can reduce the degree of wear and improve the safety.
    2. Plastics workmanship
    In plastics workmanship, its role should not be small. It can improve the compatibility of plastic-based fillers. For example, when glass is filled in plastics, the use of (triethoxy) silane coupling to treat glass can make glass plastics better compatible, improve the mechanical properties of the composite material, such as tensile strength and curvature. Some engineering plastic products, such as this treatment, can withstand a large external force, and even produce cracking and the like.
    Third, the material work
    is very effective in the material work. It can improve the adhesion of the material substrate and make the film adhere more firmly to the surface of the material. For example, adding it to the gold material can effectively prevent the film from falling off and increase the anti-corrosion performance of the material. For some gold parts used outside the country, the adhesive material containing this material is used. After a long exposure to rain, the film still maintains good adhesion, and the anti-corrosion effect lasts.
    Fourth, the bonding work
    is important for the bonding work field. It can improve the adhesion of different substrates, whether it is gold, ceramics, glass and other materials, the use of bonding materials containing (triethoxy) silane couples can achieve a high degree of adhesion. Like the bonding of some sub-products and parts, the use of this bonding can ensure that the bonding of parts is fixed during the use of the product, and it is not easy to loosen.
    What are the physical and chemical properties of 2- (trifluoromethoxy) benzenesulfonamide?
    The physical and chemical properties of (triethoxy) silane coupling agent are as follows:
    The appearance of this agent is often colorless and transparent liquid, its texture is pure, and there are no obvious impurities. Looking at its color, it is almost colorless as water, clear and translucent, without the slightest turbidity.
    Smell it, it has a special smell, but it is not pungent and intolerable, and it is still acceptable. Its smell is unique and unique in chemical materials.
    When it comes to solubility, it can be miscible with many organic solvents, such as alcohols and ether solvents, which can be mixed with each other without distinction. This property makes it easy to disperse and apply in various organic systems.
    The boiling point is a specific value. At this temperature, the liquid will change from liquid to gaseous state. This boiling point characteristic is crucial during storage and use, and can be used to control the transformation of its physical state.
    Its chemical properties are active, and the molecular structure contains active groups, which can chemically react with many substances. Especially outstanding, it can react with hydroxyl groups on the surface of inorganic substances to form stable chemical bonds, thereby realizing effective connection between inorganic and organic substances. This property is of great significance in the fields of composite preparation, surface treatment, etc., and can significantly improve the properties of materials.
    Because of its chemical activity, it is necessary to pay attention to environmental conditions during storage and avoid contact with active substances to prevent unnecessary chemical reactions and affect product quality.
    Overall, (triethoxy) silane coupling agents play an important role in many industrial fields due to their unique physical and chemical properties, becoming an indispensable key material in modern materials science.
    What are the synthesis methods of 2- (trifluoromethoxy) benzenesulfonamide?
    To make di- (triethoxy) silylpropyl glycidyl ether, the following ancient methods can be followed.
    First, the hydrogen-containing silicone oil and allyl glycidyl ether are used as materials, and the hydrosilylation reaction is carried out with the help of platinum-based catalysts. Prepare the refined hydrogen-containing silicone oil and allyl glycidyl ether and place them in a clean reactor according to a specific molar ratio. Slowly introduce the platinum-based catalyst and control the temperature in a suitable range, usually 80-120 degrees Celsius. During the reaction, continue to stir to make the material fully contact. Monitor the reaction process by gas chromatography or other methods until the silicon-hydrogen bonds in the hydrogen-containing silicone oil are exhausted and the crude product is obtained. After the method of vacuum distillation, the unreacted raw materials and by-products are removed to obtain a pure target product.
    Second, it is prepared from chloropropyl glycidyl ether and triethoxysilane. First take chloropropyl glycidyl ether and triethoxysilane and dissolve them in an appropriate amount of organic solvent, such as toluene, xylene, etc. Add an alkaline catalyst, such as potassium carbonate, sodium carbonate, etc. Warm up to 60-100 degrees Celsius and let it react. The alkaline catalyst can promote the nucleophilic substitution reaction between the two. After the reaction is completed, the catalyst and the generated salt are washed with water and separated. The organic phase is dried with anhydrous sodium sulfate, and after the solvent is removed, the target product is also obtained.
    Third, glycidyl and (triethoxysilyl) propanol are used as starting materials. Under the catalysis of acidic catalysts, the etherification reaction is carried out. Mix glycidyl and (triethoxysilyl) propanol in an appropriate proportion, add a small amount of acidic catalysts, such as p-toluenesulfonic acid. The temperature is controlled at 50-90 degrees Celsius, and the reaction number. The acidic catalyst can activate the hydroxyl group and the epoxy group to promote the reaction of the two. After the reaction, the catalyst is neutralized and purified by distillation to obtain di- (triethoxy) silylpropyl glycidyl ether.
    What is the price range of 2- (trifluoromethoxy) benzenesulfonamide in the market?
    The price of (triethoxy) silane butyric anhydride in the market often varies due to the quality and the supply and demand of the market. Those with pure and excellent quality may have a slightly higher price; those with inferior quality may have a lower price.
    In today's city, if the (triethoxy) silane butyric anhydride of ordinary quality is priced per 500 grams, or between 200 and 500 gold. However, if the market is in a hurry and the supply is limited, the price may jump up to 600 gold or 700 gold. If the supply exceeds the demand and the market is flooded, the price may fall to the spectrum of 100 gold and 200 gold.
    And its price is also related to the buyer's quantity. If you want to buy in bulk, the merchant may offer a discount to attract customers, and the larger the quantity, the lower the price. If the purchase volume is in tons, the price per 500 grams or tens of gold lower than when the purchase was zero.
    The distance of origin and transportation also affects the price. If the product is close to the city, the price may be slightly lower due to the provincial transportation cost; if the product is remote, it will be transported to the city, and the freight and loss will be added, and the price will be high. Therefore, if you want to know the exact price, you must carefully consider the market conditions and consult and compare with the merchants before you can get the appropriate price.
    What are the manufacturers of 2- (trifluoromethoxy) benzenesulfonamide?
    Di- (tri, ethoxy) silicon, acid, ethyl ester, also known as positive, silicon, acid, ethyl ester, its, production, manufacturers, many. For example, Suzhou, Hongbo, Da Silicon, Materials, Limited, Company, has been immersed in the field of silicon and materials for many years, and has accumulated rich technology. It produces di- (tri, ethoxy) silicon, and ethyl acid esters with stable quality and good purity. It has been well received by many users in the market.
    In addition, such as Jiangsu Fusheng Chemical Co., Ltd., this enterprise has a first-rate, production, equipment, and rigorous quality control system. Its products are all available in terms of quality and production capacity. It can be seen that the production of di- (tri, ethoxy) silicon and ethyl acid is widely sold at home and abroad.
    There are also Shandong Jinyufeng, Petroleum, Chemical, Limited, Company, known for its high quality, raw materials, and exquisite craftsmanship, for the production of di- (tri, ethoxy) silicon, ethyl acid, with in-depth research and rich experience, its products, in the industry, also have a high reputation.
    Manufacturers such as these all have their own strengths in the field of di- (tri, ethoxy) silicon and ethyl acid production, providing quality, quality and sufficient products for the market, which has promoted the wide application and development of this product in many industries.