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2-(Trifluoromethoxy)Benzene-1-Carbonyl Chloride

2-(Trifluoromethoxy)Benzene-1-Carbonyl Chloride

Hongda Chemical

    Specifications

    HS Code

    356275

    Name 2-(Trifluoromethoxy)Benzene-1-Carbonyl Chloride
    Molecular Formula C8H4ClF3O2
    Molecular Weight 224.56
    Appearance Colorless to light yellow liquid
    Boiling Point Approx. 200 - 205 °C
    Density 1.44 g/cm³ (approx.)
    Vapor Pressure Low at room temperature
    Solubility Soluble in organic solvents like dichloromethane, toluene
    Flash Point High (above 100 °C)
    Reactivity Reactive towards nucleophiles, undergoes hydrolysis in presence of water

    As an accredited 2-(Trifluoromethoxy)Benzene-1-Carbonyl Chloride factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing 100 - gram bottle packaging for 2-(trifluoromethoxy)benzene - 1 - carbonyl chloride.
    Storage 2-(Trifluoromethoxy)benzene - 1 - carbonyl chloride should be stored in a cool, dry, well - ventilated area. It must be kept away from heat, flames, and reactive substances like water, alcohols, and amines. Store it in a tightly - sealed container, preferably made of corrosion - resistant materials, to prevent leakage and exposure to air and moisture which can lead to decomposition.
    Shipping 2-(Trifluoromethoxy)benzene - 1 - carbonyl chloride is a hazardous chemical. It should be shipped in accordance with strict regulations, using specialized containers, with proper labeling indicating its dangerous nature, and ensuring temperature - controlled transport if required.
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    2-(Trifluoromethoxy)Benzene-1-Carbonyl Chloride 2-(Trifluoromethoxy)Benzene-1-Carbonyl Chloride
    General Information
    Historical Development
    In the past, in the field of chemistry, I studied a thing named 2- (trifluoromethoxy) benzoyl chloride. At the beginning, I explored its properties and production methods, and there were many hardships. At that time, the chemical method was still simple, and each method required repeated trials and time-consuming.
    Over the years, the chemical technology has gradually refined, and the method of preparing this product has also been improved. From the complicated beginning to the efficient later, countless efforts have been condensed in the process. In the past, colleagues worked together on this path, learned from each other, and found breakthroughs in difficulties.
    Looking at this 2- (trifluoromethoxy) benzoyl chloride now, I recall the road of exploration in the past, and I am filled with emotion. Its historical evolution has witnessed the development of chemistry, and is also a mark of the efforts of our researchers.
    Product Overview
    2 - (trifluoromethoxy) benzoyl chloride is a key intermediate in organic synthesis. It is a colorless to light yellow liquid with a pungent odor. This compound has a wide range of uses in the field of organic chemistry and is often an important raw material for the preparation of various drugs, pesticides and fine chemicals.
    Its chemical properties are active. The acid chloride group of the benzoyl chloride part has high reactivity and is easy to react with nucleophiles such as alcohols and amines to form esters, amides and other derivatives. The introduction of trifluoromethoxy gives it unique physical and chemical properties, such as enhancing the lipophilicity of the molecule and affecting the biological activity and stability of the compound.
    In the synthesis path, it often goes through a specific reaction step, starting with the corresponding phenolic compound and transforming it through a multi-step reaction. Because of its importance, it has attracted much attention in chemical production and scientific research experiments, and is of great significance to promoting the development of organic synthetic chemistry.
    Physical & Chemical Properties
    In 2024, the field of organic chemistry is booming, and various novel compounds continue to emerge. Today, there is a product called 2 - (trifluoromethoxy) benzoyl chloride (2- (Trifluoromethoxy) Benzene - 1 - Carbonyl Chloride). The appearance of this compound is colorless to light yellow liquid, and it is quite active at room temperature and pressure. Its boiling point is about a certain range, due to the force between molecules. And it has a special smell, which is derived from its unique molecular structure. In terms of solubility, it is easily soluble in most organic solvents, such as ether, dichloromethane, etc. This is based on the principle of similar miscibility. Because it contains trifluoromethoxy and benzoyl chloride groups, it is chemically active and can react with many nucleophilic reagents, such as alcohols, amines, etc., to generate a series of derivatives, which are widely used in the field of organic synthesis. It is an important object of organic chemistry research.
    Technical Specifications & Labeling
    Today there is a product called 2- (trifluoromethoxy) benzoyl chloride. Its process specifications and identification (product parameters) are the key. To make this product, you need to follow precise methods. The material ratio must be rigorous, the reaction conditions should be controlled, and the temperature, humidity and duration should be fixed. In terms of identification, the name must be accurate, and the parameters such as composition and purity must also be clear. In this way, a qualified product can be obtained. If there is a poor pool in the process specification or the identification is vague, the product can be disqualified and difficult to use where needed. Therefore, strict adherence to the process specifications and clear identification parameters are the essential principles for the preparation and application of this product.
    Preparation Method
    In order to prepare 2 - (trifluoromethoxy) benzoyl chloride, the preparation method should be investigated in detail. First of all, the raw materials need to be selected from suitable starting materials, such as benzene compounds containing specific substituents, supplemented by reagents related to the formation of trifluoromethoxy groups and acid chlorides.
    In the preparation process, the benzene ring is introduced into the trifluoromethoxy group through the reaction step, which may require specific reaction conditions, such as suitable catalyst, temperature and solvent environment. Then the corresponding group is converted into the acid chloride structure through acylation reaction.
    In this process, it is necessary to fine-tune the reaction steps, such as the length of the reaction time and the proportion of the reactants, which are all related to the purity and yield of the product. And a reasonable catalytic mechanism is constructed to speed up the reaction process and improve efficiency. In this way, it is expected to produce 2 - (trifluoromethoxy) benzoyl chloride efficiently and with high quality.
    Chemical Reactions & Modifications
    Nowadays, research on the chemical 2- (trifluoromethoxy) benzoyl chloride is crucial for chemical reactions and modifications. In the reaction, the characteristics of acyl chloride are often involved, and they interact with various reactants to form a variety of products.
    To improve its performance, it is necessary to observe the reaction conditions in detail. The rise and fall of temperature and the addition and subtraction of catalysts all have a significant impact. If the temperature is increased, the reaction rate may be increased, but it may also cause an increase in side reactions.
    In terms of modification, the physical and chemical properties can be changed by introducing specific groups. Or optimize its solubility, or increase its stability. Through continuous exploration of reaction and modification methods, we hope to obtain products with better performance, which can be used in chemical, pharmaceutical and other fields.
    Synonyms & Product Names
    2 - (trifluoromethoxy) benzene-1 -carbonyl chloride, the synonym and trade name of this thing are quite important. Guanfu chemical substances have different names, and there are many people who refer to the same thing. In this case, synonyms are words that accurately express their chemical composition and characteristics, and trade names are used in market circulation for easy identification.
    Its synonyms or according to chemical structure, in order to show the characteristics of its molecular structure, so that scholars and practitioners can clarify its essence. Trade names are mostly commercial considerations, either easy to remember or to highlight their characteristics, in order to stand out in the market.
    Although synonyms and trade names refer to this 2- (trifluoromethoxy) benzene-1-carbonyl chloride, they are used differently. Academic research, more synonyms are used to show rigor; commercial transactions, commonly used trade names, in order to promote. The two complement each other and have their own uses in the field of chemistry to help people know more about this thing.
    Safety & Operational Standards
    Specifications for the safety and operation of 2- (trifluoromethoxy) benzoyl chloride
    Fu2- (trifluoromethoxy) benzoyl chloride is an important chemical substance that is used in many fields. However, it has special properties, which are related to safety and operation standards, and cannot be ignored.
    Its chemical properties are active and prone to violent reactions in contact with water. Therefore, when storing, it must be placed in a dry, cool and well-ventilated place, away from water sources and moisture. The storage container used should be made of corrosion-resistant material and tightly sealed to prevent leakage.
    When operating, operators must strictly wear protective equipment, such as protective clothing, protective gloves and goggles, to prevent the substance from coming into contact with the skin and eyes. In case of inadvertent contact, rinse with plenty of water quickly and seek medical attention immediately.
    In terms of ventilation, the operating environment needs to have a good ventilation system to prevent the accumulation of harmful gases. If it is an indoor operation, it should be carried out in a fume hood to ensure that the gas is discharged in time.
    Furthermore, this substance is toxic and cannot be inhaled. Therefore, avoid dust or volatile gases during operation. In the event of a leak, irrelevant personnel should be evacuated quickly, and fire should not be allowed to approach. To deal with leaks, appropriate adsorption materials should be collected and then properly disposed of.
    In the disposal of waste, relevant regulations should also be followed. Discarded 2- (trifluoromethoxy) benzoyl chloride should not be discarded at will, but should be handled by professional institutions to ensure environmental safety.
    In summary, the safety and operating standards of 2- (trifluoromethoxy) benzoyl chloride are of great importance, and practitioners must strictly abide by them to ensure the safety of personnel and the environment.
    Application Area
    Today there is a product called 2- (trifluoromethoxy) benzoyl chloride. This product has a wide range of uses. In the field of medicine, it can be used as a key intermediate to help synthesize special drugs, cure various diseases, and solve the suffering of the world. In the material industry, it can participate in the creation of new functional materials, or have excellent stability and unique chemical properties. It is used in high-tech products to promote technological innovation. In the field of fine chemicals, it is an important raw material for the preparation of high-end fine chemicals, giving products unique quality and characteristics. This 2- (trifluoromethoxy) benzoyl chloride, with its unique characteristics, is active in many application fields, is an indispensable substance in today's chemical research and industrial production, and has a far-reaching impact on the development of related industries.
    Research & Development
    In recent years, I have studied 2- (trifluoromethoxy) benzoyl chloride in the field of organic synthesis. Its activity is quite useful in organic synthesis.
    At the beginning, the method of its preparation was studied. After many tests, the influence of different reaction conditions was observed. Temperature, reagent ratio, catalyst selection were all carefully investigated. After repeated exploration, a better method was obtained, which can increase its yield and maintain its purity.
    Times, explore its application in various reactions. React with alcohols, amines, etc., to form esters, amides and other compounds. Examine the reaction mechanism and the structure of the product. It was found that it can introduce a special trifluoromethoxy group to give the product unique physicochemical properties.
    Today, although progress has been made in the research of this product, there is still a long way to go. In the future, it will expand its application field and find more innovative methods. Hope to make greater progress in the organic synthesis industry to promote the development of this field.
    Toxicity Research
    Today there is a substance called 2- (trifluoromethoxy) benzoyl chloride. As a chemical researcher, I am specially investigating its toxicity.
    The toxicity of this substance is related to the safety of all living beings. Examining its properties carefully, we can see that it may have irritating properties, touch the skin, cause discomfort, enter the eyes, and risk damage. If inhaled inadvertently, or disturb the breathing system, it will cause cough and asthma.
    The method of inquiry is based on experiments to observe its effect on living beings. Take various animals as a test to observe its physiological changes. Also consider its transformation in the environment, with other things, and the law of its dissemination.
    We should be very careful. When studying this thing, we should take all measures to ensure the safety of ourselves and our surroundings. Only by understanding the principle of its toxicity can we make good use of it, avoid its harm and promote its benefits, and contribute to the progress of the world.
    Future Prospects
    In the future world, the work of chemical engineering will be great. Today there is a thing called 2- (trifluoromethoxy) benzoyl chloride, which is in the field of chemical engineering, like the stars waiting to shine. This compound is unique in nature and has a wide range of uses.
    We can use it in the process of synthesis, and it is expected to be developed into a multi-disease material, and it will be new. Or we can help people make miraculous prescriptions to solve the world's diseases. In the field of materials, it also exhibits extraordinary strength, which can make materials have special properties and can be used in many high-tech.
    In the future, when scientific researchers explore in depth, they will be able to explore more possibilities. To fully utilize its subtlety for the benefit of the world, this is the heart of our researchers, and it is also the work of the undeveloped.
    Where to Buy 2-(Trifluoromethoxy)Benzene-1-Carbonyl Chloride in China?
    As a trusted 2-(Trifluoromethoxy)Benzene-1-Carbonyl Chloride manufacturer, we deliver: Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements. Technical Excellence: Precision-engineered solutions backed by R&D expertise, from formulation to end-to-end delivery. Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.
    Frequently Asked Questions

    As a leading 2-(Trifluoromethoxy)Benzene-1-Carbonyl Chloride supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

    What are the main uses of 2- (trifluoromethoxy) benzoyl chloride?
    Ethyl (triethoxy) silicoacetate is an important member of the family of organosilicon compounds. It has a wide range of uses and plays a key role in many fields.
    In the field of materials science, ethyl (triethoxy) silicoacetate is often used as a coupling agent. The cap contains both siloxy groups that can chemically react with the hydroxyl groups on the surface of inorganic substances and organic functional groups that can interact with organic substances. Such a unique structure makes it possible to build a bridge between inorganic and organic materials and strengthen the bonding force between the two. For example, in glass fiber reinforced plastics, after adding this substance, the surface of the glass fiber can be modified, the compatibility with the resin matrix is greatly improved, the mechanical properties of the composite material are significantly enhanced, and the indicators such as strength and toughness are optimized, so it is widely used in aerospace, automobile manufacturing and other industries that require strict material properties.
    In the coating industry, (triethoxy) ethyl silicate acetate also plays an important role. It can participate in the coating film formation process, and the organic polymer and inorganic filler are closely connected through chemical reaction, which improves the adhesion of the coating to the substrate, and enhances the hardness and wear resistance of the coating. The modified coating not only has excellent protective performance, but also has good chemical corrosion resistance, can resist acid and alkali and other chemical substances, and is widely used in surface protection in construction, ships and other fields.
    In addition, in the field of organic synthesis, ethyl (triethoxy) silicoacetate, as an important intermediate, participates in many organic synthesis reactions. Due to the special electronic effect and spatial structure of silicon atoms in the molecule, it can guide the selective reaction to synthesize organic compounds with specific structures and functions, providing a powerful tool for the development of organic synthesis chemistry.
    What are the physical properties of 2- (trifluoromethoxy) benzoyl chloride?
    (Trihydroxyethyl) aminomethane buffer is a commonly used reagent for biochemical experiments. Its physical properties are quite characteristic.
    Looking at its morphology, at room temperature, it is mostly white crystalline powder, with a fine and uniform texture, just like the first snow in winter, pure and fine texture.
    When it comes to solubility, this substance has excellent solubility in water, just like ice and snow into a stream, it can quickly melt with water to form a uniform solution. In common organic solvents, such as ethanol and ether, the solubility is weak, just like oil and water are difficult to mix, only slightly soluble or almost insoluble.
    Besides the melting point, the melting point of (trihydroxyethyl) aminomethane buffer is quite considerable, about 171-172 ° C. Such a high melting point allows it to maintain a stable solid state under the general experimental environment temperature.
    Its density is also fixed, about 1.353g/cm ³, indicating that its unit volume mass is moderate and has certain density characteristics.
    As for the smell, the substance is almost odorless, just like a quiet lake water, and there is no odor emission. This characteristic makes it not interfere with the experimenter's operation and judgment due to the smell during the experimental use, nor will it cause odor-related effects on the experimental system.
    In terms of hygroscopicity, (trihydroxyethyl) aminomethane buffer has a certain degree of hygroscopicity. Like a dry sponge placed in humid air, it will absorb moisture in the air, so it is necessary to pay attention to moisture when storing to prevent moisture absorption from affecting its quality and performance.
    What are the chemical properties of 2- (trifluoromethoxy) benzoyl chloride?
    The chemical properties of di- (triethoxy) sodium silicoacetate solution are as follows:
    This solution has good stability. Under normal conditions, its chemical structure can be maintained relatively stable, and it is not easy to spontaneously decompose or other violent chemical reactions. Because of its silicon-oxygen-carbon bond, this structure imparts a certain degree of chemical inertness to the substance, allowing it to exist more stably in a certain environment.
    In an acid-base environment, it exhibits specific reaction characteristics. In an acidic environment, the ethoxy group in it may undergo a gradual hydrolysis reaction. The stronger the acidity, the faster the hydrolysis rate. During hydrolysis, the ethoxy group will be replaced by a hydroxyl group to form hydroxyl-containing silicon compounds and ethanol. This hydrolysis reaction is a reversible reaction. If the reaction conditions, such as pH and temperature, can be controlled, the degree of hydrolysis can be adjusted.
    When in an alkaline environment, the stability of di- (triethoxy) sodium silicate acetate solution is also affected. Alkaline substances may promote reactions such as the breaking of silicon-oxygen bonds, but compared with the hydrolysis of ethoxy groups under acidic conditions, the reaction mechanism in alkaline environments is more complex, involving changes in the electron cloud density around silicon atoms and the interaction between acetate ions and bases.
    In addition, the solution can react with some metal ions. Silicon atoms and oxygen atoms in the solution have lone pairs of electrons, which can form coordination bonds with metal ions, and then form stable complexes. This property has important application value in specific fields, such as material surface treatment, catalyst preparation, etc., and can change the surface properties of materials or affect the activity and selectivity of catalytic reactions through complexation.
    Furthermore, in terms of solubility, sodium di- (triethoxy) silicoacetate has good solubility in water because it contains hydrophilic acetate ions and ethoxy groups with a certain polarity. At the same time, it also has a certain solubility in some polar organic solvents. This solubility provides convenience for its use in many chemical processes and industrial applications. It can be uniformly dispersed in the reaction system or application system to better exert its chemical effect.
    What are the preparation methods of 2- (trifluoromethoxy) benzoyl chloride?
    To prepare di- (triethoxy) silethyl borate, the method is as follows:
    First take an appropriate amount of boric acid and place it in a clean reaction vessel. Then slowly add a certain amount of triethoxy silethyl alcohol. The ratio of the two needs to be precisely prepared to obtain the best effect. At the same time, add an appropriate amount of catalyst, which can promote the rate of reaction and make the reaction more smooth.
    When reacting, the temperature and pressure need to be strictly controlled. Gradually raise the temperature of the reaction system to a suitable range, usually within a certain temperature range, the reaction rate and product purity can be optimized. At this temperature, continue to stir to make the reactants fully mixed and contacted to facilitate the progress of the reaction.
    The control of pressure is also the key. Maintaining a moderate pressure can ensure the stable progress of the reaction and avoid accidents. During the reaction process, it is necessary to pay close attention to the reaction phenomenon, observe the change of its color and state, and judge the process of the reaction.
    After the reaction is completed, the product is separated and purified. Distillation can be used to remove impurities at low boiling point and retain the main product. Later, extraction, crystallization, etc. are used to further purify, except for other impurities, so that the purity of the product can reach the required standard.
    In this way, high purity bis- (triethoxy) silethyl borate can be obtained. The whole preparation process requires fine operation in each step to achieve the desired effect.
    What are the precautions for 2- (trifluoromethoxy) benzoyl chloride in storage and transportation?
    Di- (trihydroxymethyl) aminomethane buffer during storage and transportation, there are a number of important things to pay attention to.
    When storing this liquid, temperature control is very critical. It should be stored in a cool and dry place, away from direct sunlight, to prevent the buffer properties from changing due to excessive temperature. Generally speaking, under room temperature conditions, it can be stored properly in most cases; however, if the temperature is too high, such as during the summer heat season, it may need to be placed in a refrigerated environment to maintain its stability. If the temperature is too low, it may freeze the buffer, causing damage to its composition structure and affecting the effect of future use.
    Furthermore, the storage container should also be carefully selected. When using chemically stable materials that do not react with the buffer, such as glass or containers made of specific plastic materials. Glass containers have good chemical stability and are not easy to interact with buffer components; if some plastic materials are selected improperly, small molecules may dissolve and contaminate the buffer. Therefore, when choosing plastic containers, it is necessary to ensure that they have no adverse effects on the buffer.
    As for transportation, the buffer packaging must be firm. Buffer is mostly liquid. If the packaging is not solid, it will vibrate and collide during transportation, which will easily cause container damage and liquid leakage. Appropriate protective measures should be installed in the packaging, such as filling buffer materials, to reduce external impact during transportation. And the transportation environment temperature also needs to be paid attention to to to avoid too high or too low temperature affecting the quality of the buffer.
    In addition, whether it is storage or transportation, pay attention to clear labels. Labels should clearly indicate key information such as buffer name, concentration, preparation date, valid period, etc., so that users can know the status of the buffer and take it correctly. At the same time, they can be used reasonably according to the valid period to avoid deviations in experiments or production caused by the use of expired buffers.