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What are the main uses of 2- (trifluoromethoxy) benzene-1,4-dicarboxylic acid?
2-% (trihydroxymethyl) amino-1,4-succinic acid, often referred to as "Tris succinic acid", is widely used.
In the field of biochemistry and molecular biology, it plays a key buffer role. In many biological experiments, such as the separation, purification and analysis of proteins and nucleic acids, it is necessary to strictly maintain a stable pH environment. Tris succinic acid, with its excellent buffering ability, can precisely control the pH of the solution within a specific range, providing protection for the activity and structural stability of biological macromolecules, so that the experiment can be carried out smoothly and the results are more reliable.
It also has important applications in medical research. In the development of pharmaceutical preparations, in order to ensure the stability and effectiveness of the drug, the pH of the preparation needs to be precisely regulated. Tris succinic acid can play this role, helping to create a suitable environment for the preservation and function of the drug. At the same time, in the synthesis process of some drugs, it may also act as a reaction medium or a reagent participating in the reaction, which affects the drug synthesis path and product quality.
In addition, in the field of food industry, it is also useful. In the processing and storage of some foods, in order to prevent the deterioration of food ingredients due to changes in pH, Tris succinic acid can be used as a food additive to adjust the pH of the food system, prolong the shelf life of the food, and maintain the flavor and quality of the food.
In the production of chemical products such as coatings and inks, Tris succinic acid is also valuable. It can adjust the pH of the product, affect the rheological properties, stability and drying properties of the product, thereby improving the quality and performance of the product.
What are the physical properties of 2- (trifluoromethoxy) benzene-1,4-dicarboxylic acid?
2- (triethoxy) silicon-1,4-diacetic acid is an organic compound, and its physical properties are particularly important for its application in various fields.
This compound is mostly liquid under normal conditions, with an appearance or colorless and transparent, or a microstrip color, with a certain fluidity. Looking at its odor, it may have a specific taste, but the odor intensity may vary depending on purity and environment.
Its boiling point is one of the key physical properties. Due to the interaction of atoms and chemical bonds in the molecular structure, its boiling point is specific. At a suitable temperature, the compound gradually changes from liquid to gaseous state. The boiling point is determined by intermolecular forces, such as van der Waals force, hydrogen bond, etc. The intermolecular force of this compound keeps the boiling point in the corresponding range. The boiling point is an important factor to consider when separating, purifying and controlling the reaction conditions.
Melting point should not be ignored. The temperature of the compound when it is converted from solid to liquid is the melting point. The melting point is related to the degree of close arrangement of molecules and the lattice energy. The molecular structure with regular close arrangement has high lattice energy and high melting point. Knowing the melting point is of great significance for storage, transportation and setting specific reaction initiation conditions.
In terms of solubility, the compound has good solubility in some organic solvents. This characteristic is due to the matching of its molecular polarity with the polarity of the solvent. Solvents and solutes with similar polarity, the intermolecular force is conducive to the dispersion of the solute in the solvent. Such as some alcohols and ether organic solvents, it can be well miscible with them. However, the solubility in water may be limited, because its molecular structure is not highly hydrophilic. Solubility determines its dispersion and reaction status in different systems.
Density is also a significant physical property. Its density reflects the mass of the substance per unit volume. Density is related to molecular mass and intermolecular distance. Higher molecular mass and closely arranged molecules, the density is in a specific range. In mixed systems, density affects the stratification and distribution of substances, and is an important parameter in chemical production and experimental operations.
In summary, the physical properties of 2- (triethoxy) silicon-1,4-diacetic acid, such as appearance, odor, boiling point, melting point, solubility, density, etc., are interrelated and have their own uses, providing a foundation for in-depth understanding and rational use of this compound.
Is 2- (trifluoromethoxy) benzene-1,4-dicarboxylic acid chemically stable?
2-% (triethoxy) silicon-1,4-dicarboxylic acid is an organic compound, and its chemical stability needs to be discussed from a polyterminal perspective.
In this compound, the silicon atom is connected with a triethoxy group, and the oxygen atom in the ethoxy group can have an electronic effect with the silicon atom due to its lone pair of electrons, which has an impact on the molecular stability. From the perspective of bond energy, the silicon-oxygen bond energy is quite high, which makes the structure of this part relatively stable. In the 1,4-dicarboxylic acid part, the carboxyl group has a certain activity, because it contains a carbonyl group and a hydroxyl group, and the two affect each other. The carbonyl group is electron-absorbing, which makes the hydroxyl hydrogen more easily dissociated, showing a certain acidity. Under normal circumstances, if the temperature and humidity are appropriate and there is no special chemical reagent interference, this compound can remain relatively stable for a certain period of time.
However, in case of high temperature, the intra-molecular energy increases, the vibration of chemical bonds intensifies, and the ethoxy group may break, or the carboxyl group dehydrates, causing its stability to decrease. If placed in a strong acid-base environment, the acid can catalyze the hydrolysis of ethoxy groups, and the base can neutralize with the carboxyl group, which will destroy the original structure of the molecule, change its chemical properties and lose its stability.
Therefore, the stability of 2-% (triethoxy) silicon-1,4-dicarboxylic acid is not absolute and will vary according to environmental conditions such as temperature, pH, and the presence or absence of other reactants.
What are the synthesis methods of 2- (trifluoromethoxy) benzene-1,4-dicarboxylic acid?
The synthesis method of 2-% (triethoxy) silicon-1,4-diacid is a very important topic in the field of organic synthetic chemistry. There are various synthetic paths, each with its own advantages and disadvantages. The following are common synthetic methods:
First, the reaction between a silicon-containing halide and a diacid derivative as a raw material. In this method, a silicon-containing halide, such as triethoxy silicon halide, is first taken with a diacid derivative, such as 1,4-diacid esters, and reacts in an organic solvent (such as toluene, dichloromethane, etc.) under the action of an appropriate base (such as potassium carbonate, sodium carbonate, etc.). The base can neutralize the hydrogen halide generated by the reaction and promote the positive reaction. This reaction requires attention to control the reaction temperature and time. If the temperature is too high or the time is too long, it may cause side reactions and reduce the purity and yield of the product.
Second, the reaction between silanol and dianhydride is used. Silica compounds, such as triethoxysilanol, are reacted with 1,4-dianhydride in the presence of a catalyst. Commonly used catalysts include organotin compounds and titanate compounds. Such catalysts can effectively reduce the activation energy of the reaction and speed up the reaction rate. The reaction is usually carried out under mild conditions, which can avoid side reactions caused by high temperature, and the product selectivity is high. However, the choice and dosage of catalysts need to be precisely controlled, otherwise the reaction process and product quality will be affected.
Third, the synthesis through the participation of organometallic reagents. The organometallic reagents such as organolithium and organomagnesium are reacted with silicon-containing halides and diacid derivatives in sequence. First, the organometallic reagents undergo nucleophilic addition reaction with diacid derivatives to generate intermediate products, and then react with silicon-containing halides to construct the structure of the target product. Although this method can achieve more complex structure construction, organometallic reagents are usually more active, demanding reaction conditions, need to be operated in anhydrous and oxygen-free environments, and the cost is high.
The above methods have their own advantages and disadvantages. In actual synthesis, it is necessary to comprehensively consider many factors such as the availability of raw materials, the difficulty of reaction conditions, the cost, and the purity and yield of the product, and carefully select the appropriate synthesis method.
What is the market price of 2- (trifluoromethoxy) benzene-1,4-dicarboxylic acid?
I have not heard the exact price of "2 - (trihydroxymethyl) amino - 1,4 - diacetic acid" in the market. This is a chemical reagent, and its price often varies due to changes in quality, purity, origin, purchase quantity, and market supply and demand.
If it is high purity and comes from a well-known manufacturer, its price may be expensive; if you buy in bulk, merchants may have discounts. To know its price, you can consult the chemical reagent supplier, such as Sinopharm Group Chemical Reagent Co., Ltd., or search on the online chemical reagent sales platform, such as Gade Chemical Network, etc. There may be quotations from merchants on it, which can be used for reference and comparison, in order to get a more accurate price.