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2-Nitro-4-Trifluoromethylbromobenzene

2-Nitro-4-Trifluoromethylbromobenzene

Hongda Chemical

Specifications

HS Code

232904

Chemical Formula C7H3BrF3NO2
Molar Mass 270.003 g/mol
Appearance Colorless to light yellow liquid
Boiling Point 206 - 208 °C
Melting Point N/A
Density 1.832 g/cm³
Solubility In Water Insoluble
Solubility In Organic Solvents Soluble in common organic solvents like ethanol, ether
Flash Point 91 °C
Vapor Pressure Low at room temperature
Odor Characteristic, pungent

As an accredited 2-Nitro-4-Trifluoromethylbromobenzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

Packing & Storage
Packing 100g of 2 - nitro - 4 - trifluoromethylbromobenzene packaged in a sealed glass bottle.
Storage 2 - nitro - 4 - trifluoromethylbromobenzene should be stored in a cool, dry, well - ventilated area. Keep it away from heat sources, open flames, and oxidizing agents. Store it in a tightly sealed container, preferably made of corrosion - resistant materials. Label the storage container clearly to prevent misidentification and ensure proper handling and safety.
Shipping 2 - nitro - 4 - trifluoromethylbromobenzene is shipped in well - sealed, corrosion - resistant containers. It follows strict hazardous chemical shipping regulations, with proper labeling indicating its properties to ensure safe transportation.
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2-Nitro-4-Trifluoromethylbromobenzene 2-Nitro-4-Trifluoromethylbromobenzene
General Information
Historical Development
The industry of chemical industry is changing with each passing day. All kinds of compounds have their own origins and rheological changes. Today's words 2 - Nitro - 4 - Trifluoromethylbromobenzene this thing, at the beginning of its birth, it was really due to the efforts of the wise men. In the past, the engineers worked in the laboratory day and night to explore the method of synthesis. At the beginning, there were many setbacks, and the road to synthesis was full of thorns. However, everyone was unyielding, tried again and again, and improved their skills.
From the original simple method, the yield was low, and there were many impurities. After several years of grinding, the technique was finally refined, and the yield gradually increased and the purity was also high. This compound is gradually used in medicine, materials and other fields. It is either the cornerstone of new drug research and development, or the improvement of material properties. Its historical evolution has witnessed the path of chemical industry, from ignorance to Qingming, the work of all craftsmen, indelible, adding a touch of bright color to the long river of chemical industry, guiding latecomers, forging ahead, and opening up more unknown realms.
Product Overview
2 - Nitro - 4 - Trifluoromethylbromobenzene is an essential chemical in organic synthesis. Its properties are solid with specific melting and boiling points, and its appearance may be white to light yellow crystalline. This compound has unique chemical properties due to its containing nitro, trifluoromethyl and bromine atoms.
Nitro has strong electron absorption, which reduces the electron cloud density of the benzene ring, making it more prone to nucleophilic substitution. The introduction of trifluoromethyl significantly changes the physical and chemical properties of the molecule, enhancing the stability and lipid solubility of the compound. Bromine atoms provide an active check point for subsequent derivatization reactions, which can be converted into other functional groups through various reactions.
In the field of organic synthesis, 2-Nitro-4-Trifluoromethylbromobenzene is often used as a key intermediate for the preparation of functional compounds in the fields of drugs, pesticides and materials science, which is of great significance to promote the development of related fields.
Physical & Chemical Properties
2 - Nitro - 4 - Trifluoromethylbromobenzene, the chemical material is also. Its physical properties are low, the color is low, and it is often solid under the pressure, and has a special taste. In the melting process, if it encounters high melting, the melting liquid will be high. Its boiling time is also fixed, and it is affected by the phase degree, so it will be easily dispersed.
In terms of chemical properties, the nitro group, trifluoromethyl group and bromine atoms in this compound interact, resulting in high activity. Nitro is oxidizing and can be reactive with multiple substitutions. The presence of trifluoromethyl group alters the solubility of the molecule and affects its solubility in different solubilities. Bromine atom activity, which can be used for the construction of new technologies from specific reactions, is an important raw material for synthesis, and plays an important role in the field of chemical research and engineering.
Technical Specifications & Labeling
There is a product today called 2 - Nitro - 4 - Trifluoromethylbromobenzene. To clarify its technical specifications and identification (product parameters), it is necessary to investigate in detail.
The technical specifications of this product are related to its quality, content, etc. In terms of quality, it should have specific physical and chemical characterizations. The amount of its content also needs to be accurately determined to meet the requirements used.
On the label, the product parameters should be clear and clear. The name must be accurate, so that the person who sees it is known as 2 - Nitro - 4 - Trifluoromethylbromobenzene. It is also necessary to indicate the origin, batch and other key information for traceability and control. On the packaging, the logo is also indispensable, the handwriting is clear, and it will not fade away for a long time. In this way, only on the technical specifications and labels (product parameters) can this product be complete and usable without error.
Preparation Method
This 2 - Nitro - 4 - Trifluoromethylbromobenzene, the raw materials used and the preparation method, reaction steps and catalytic mechanism are described in detail as follows.
For raw materials, choose trifluoromethyl bromobenzene as the starting material, which is the key thing. Preparation and reaction steps: First put p-trifluoromethyl bromobenzene in a suitable reactor, add an appropriate amount of mixed acid, nitric acid and sulfuric acid in a certain proportion, this mixed acid is the important agent for nitrification. Warm up to the appropriate temperature, about 50 to 60 degrees Celsius, keep it stable, and allow it to fully react. This process requires strict control of temperature and time, about two hours, before the reaction can be completed. In terms of catalytic mechanism, sulfuric acid plays a catalytic role in this reaction, which can enhance the nitrification ability of nitric acid and make the reaction easier to proceed. After this operation, 2-Nitro-4-Trifluoromethylbromobenzene can be obtained. However, the product may contain impurities, and subsequent purification steps are required to meet the requirements of high purity products.
Chemical Reactions & Modifications
Fu 2 - Nitro - 4 - Trifluoromethylbromobenzene, in the field of chemistry, its reaction and modification are of great importance to researchers. Looking at past experiments, the reaction path often varies according to the accompanying reagents and conditions.
When encountering nucleophiles, the nitro and bromine atoms often change. However, this reaction is also restricted by spatial hindrance and electronic effects. If the temperature, pressure, and solvent properties of the reaction can be adjusted well, the reaction can be directed to the desired path.
As for modification, in order to increase its activity or change its physical and chemical properties, he is often added to the benzene ring with other groups. This can reduce its polarity and solubility, which is of great benefit to the production of drugs and materials. Our researchers should study various factors in detail to clarify the law of its reaction and seek a good method of modification.
Synonyms & Product Names
Today there is a product, the name 2 - Nitro - 4 - Trifluoromethylbromobenzene. This chemical product has various other names in the industry. Due to its chemical structure and characteristics, there are many synonymous names to express it.
Or because of its combination of nitro, trifluoromethyl and bromine atoms, chemists have given it different names for research and communication. Some call it directly because of its structural characteristics, and some name it according to its use and source. As for trade names, merchants also have different names for their characteristics, uses or distinctions.
These synonymous names and trade names, although different, refer to this 2 - Nitro - 4 - Trifluoromethylbromobenzene. In the field of chemical research, production and trade, it is necessary to clarify its many names, which can facilitate smooth communication and correct operation, and also help the inheritance of academic and industry knowledge and the advancement of technology.
Safety & Operational Standards
2 - Nitro - 4 - Trifluoromethylbromobenzene Safety and Operating Specifications
2 - Nitro - 4 - Trifluoromethylbromobenzene, the things that are destroyed are also. In the environment of, follow the safety
#Second, the operation of the
operation of the
, must be anti-damage equipment. Operators wear the right clothes for use, wearing anti-wear gloves, which must be able to resist the corrosion of this compound. And wear the right eyes, so as to avoid the loss of droplets.
The operation should be carried out in the pass, so that the speed of the operation is arranged, not in the room. Take it, use it as a tool, and avoid it from coming out. If you take it with a measuring device, use a fine tool, and take it according to the required amount, not more or less.
#3. If you accidentally place
on the surface of the skin, quickly wash it with a large amount of water and soap. If there is any problem, you should be in a hurry. If it enters the eyes, immediately use physiological water or water to wash it, and then wash the eyeballs thoroughly, and ask for help as soon as possible.
If it is accidentally placed on the surface or the ground, first cover it with dangerous sources such as fire sources, and cover it with suitable adsorbents, such as vermiculite and sand, carefully collect it, and place it in a container of used materials. Do not pour it out.
Therefore, in the research and application of 2-Nitro-4-Trifluoromethylbromobenzene, safety is essential and operation is followed, so as to ensure the safety and safety of the person.
Application Area
Nowadays, there are chemical substances called 2-Nitro-4-Trifluoromethylbromobenzene. The application field of this substance is very wide. In the field of medicinal chemistry, it is the key raw material for the synthesis of special drugs. With its unique chemical structure, it can participate in many reactions to obtain ingredients that are effective against diseases.
In materials science, it has also emerged. It can integrate new materials through specific processes to improve the properties of materials, such as stability and corrosion resistance. Its unique chemical properties enable materials to maintain good condition in special environments.
In the field of agricultural chemistry, it can be used to develop high-efficiency pesticides. With its chemical activity, it can effectively kill pests and has a relatively small impact on the environment, contributing to the sustainable development of agriculture. This is the outline of the 2-Nitro-4-Trifluoromethylbromobenzene application field.
Research & Development
In recent years, I Trifluoromethylbromobenzene this object in 2 - Nitro - 4 -, and devoted myself to studying it, hoping to make some progress. At the beginning, I explored its synthesis method, painstakingly searched for various paths, or tried the old method, or created a new way, and repeated experiments to test the advantages and disadvantages of each method. Although I have been frustrated many times, I have never given up.
Then, observe its physical properties, under different temperatures and humidity, record its changes in detail, study the law of its reaction with other things, hoping to expand its application. During this time, I also communicated with my colleagues to discuss problems and gain a lot.
At present, there has been a slight success. The synthesis method has gradually improved, and the purity of the product has also improved. However, knowing that the road ahead is still far away, we should continue to study in the future, and strive to make greater breakthroughs in the research and development of this product, so as to contribute to the industry and achieve a higher level.
Toxicity Research
The toxicity of 2 - Nitro - 4 - Trifluoromethylbromobenzene this chemical is related to many aspects. Looking at its chemical structure, the presence of nitro and trifluoromethyl may cause it to have a specific chemical activity, which may react with molecules in vivo, thus showing toxicity.
Experiments have shown that in vitro cell experiments, at a certain concentration, the substance can cause changes in cell activity, affect the normal metabolism of cells, or damage the structure and function of cells. In vivo experiments, small animals were used as subjects. After ingesting a certain amount, some physiological indicators were abnormal, and there were signs of damage to the organs.
However, there are still unfinished toxicity studies. Its stability in different environmental media and toxicity of degradation products still need to be studied in detail. And the chronic effects of long-term low-dose exposure on organisms need to be further studied, so as to better understand the full picture of its toxicity and provide a solid basis for its safe use and prevention and control.
Future Prospects
Fu 2 - Nitro - 4 - Trifluoromethylbromobenzene, it is also a matter of transformation. I have studied it now, and it is possible to improve it in the future.
The properties of this compound are unique, and it can be used in multiple domains. In the field of development, it may be able to be skillfully repaired, and it can be used to treat diseases and save people. In the field of materials, it may be possible to study new materials, improve the properties of materials, and apply it to high-end technology.
And if its synthesis method can be improved in one step, improve the efficiency and reduce the cost, it will definitely be more widely used. Our scientific researchers, with their efforts, explore its possibilities. In the future, 2 - Nitro - 4 - Trifluoromethylbromobenzene can expand the color, promote the transformation and related fields, and create a better world.
Where to Buy 2-Nitro-4-Trifluoromethylbromobenzene in China?
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Frequently Asked Questions

As a leading 2-Nitro-4-Trifluoromethylbromobenzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

What are the main uses of 2-nitro-4-trifluoromethylbromobenzene?
2-% heptyl-4-triethylamino phenyl ether is a commonly used chemical raw material in organic synthesis. It is mainly used in various fields and has outstanding functions.
In the field of medicinal chemistry, it is an important intermediate for the synthesis of various drugs. Due to its special chemical structure, it can participate in a series of reactions to build the skeleton of drug-active molecules. For example, in the preparation of some cardiovascular disease treatment drugs, 2-% heptyl-4-triethylamino phenyl ether can introduce key functional groups through specific reaction steps to endow the drug with specific pharmacological activity and help it achieve the effect of regulating cardiovascular physiology.
In the field of materials science, it also has extraordinary performance. It can be used as a synthetic raw material for functional materials, such as materials with special optical or electrical properties. With it as a starting material, through polymerization or other chemical modifications, optical materials that can respond to specific wavelengths of light can be prepared, or organic conductors with unique electrical conductivity. It has potential applications in optoelectronic devices, sensors and other fields.
In the dye industry, 2-% heptyl-4-triethylamino phenyl ether plays an important role. It can be used as a key component in the synthesis of specific color dyes. Because its structure can absorb and emit light of specific frequencies, through appropriate chemical modification and preparation, dyes with bright colors and good stability can be prepared. It is widely used in textile, printing and dyeing and other industries to give fabrics a colorful color.
Furthermore, in the research and practice of organic synthetic chemistry, it is often used as a reaction substrate or reagent to explore novel chemical reaction paths and methods. Through in-depth research on its reactivity, chemists have developed many efficient and selective organic synthesis strategies, which promote the sustainable development of organic synthetic chemistry.
In short, 2-% heptyl-4-triethylamino phenyl ether, with its unique chemical structure and properties, has shown indispensable value in many fields such as medicine, materials, dyes and organic synthesis, providing important support for technological progress and innovative development in various fields.
What are the synthesis methods of 2-nitro-4-trifluoromethylbromobenzene?
To make 2-cyano-4-trifluoromethylbenzonitrile, the following ancient methods can be used:
The method of nucleophilic substitution is first introduced. Start with halogenated aromatics, such as 2-halo-4-trifluoromethylhalobenzene, and dance with cyanide nucleophiles. Cyanides can be selected from potassium cyanide, sodium cyanide, or zinc cyanide, in suitable solvents, such as dimethylformamide (DMF), dimethyl sulfoxide (DMSO), accompanied by catalysts, such as cuprous iodide and palladium catalysts, heated at controlled temperature, and the halogen atom is replaced by a cyano group, so 2-cyano-4-trifluoromethylbenzonitrile is obtained The reaction is exquisite, because the activity of the nucleophilic reagent corresponds to the structure of the substrate, and the solvent and catalyst are also key to synergistically promote the substitution effect.
There are also those who use aryl boric acid or borate esters as raw materials. Let 2-borate-4-trifluoromethylbenzene derivatives meet the cyanogen source, the cyanide source may be trimethylsilyl cyanide (TMSCN), under the catalysis of transition metals, such as palladium, rhodium and other metal complexes, with the help of bases, cyanylation is achieved. In this process, the preparation of aryl boronic acid needs to be exquisite, and the preparation of the catalytic system is crucial to success or failure. The type and dosage of bases also affect the reaction process. After many twists and turns, the final product is 2-cyano-4-trifluoromethylbenzonitrile.
Furthermore, it can be converted from cyanide-containing precursors. For example, starting with 2-nitro-4-trifluoromethylbenzaldehyde, it is first reacted with hydroxylamine to obtain oximide, and then dehydrated to 2-cyano-4-trifluoromethylbenzonitrile by the action of dehydrating agents, such as phosphorus pentoxide and acetic anhydride. This path makes use of the wonders of functional group transformation. The oximization and dehydration steps each have their own requirements. The choice of dehydrating agent and the control of reaction conditions affect the purity and yield of the product.
The above methods have their own advantages, or the raw materials are easy to obtain, or the conditions are mild, or the yield is considerable. It is necessary to weigh the factors of raw material cost, reaction difficulty, and product separation according to the actual situation, and choose carefully to achieve the purpose of preparing 2-cyano-4-trifluoromethylbenzonitrile.
What are the physical properties of 2-nitro-4-trifluoromethylbromobenzene?
2-% cyano-4-trifluoromethylbenzonitrile, which is a commonly used raw material in organic synthesis. Its physical properties are as follows:
Under normal temperature and pressure, it is mostly white to light yellow crystalline powder, uniform and delicate. This form is conducive to storage and access, and is also easy to disperse and participate in various chemical reactions.
When talking about the melting point, it is about 70 ° C to 75 ° C. The melting point is relatively low, and under moderate heating conditions, it is easy to change the state of matter. This property is particularly critical in some synthetic reactions that require precise temperature control.
In terms of boiling point, it is roughly in the range of 270 ° C to 280 ° C. The higher boiling point indicates that it has good thermal stability. In a relatively high temperature environment, it can also maintain the stability of its own chemical structure, and it is not easy to volatilize and lose, which helps the reaction to proceed smoothly at higher temperatures.
Solubility is quite important. 2-% cyano-4-trifluoromethylbenzonitrile is soluble in common organic solvents, such as dichloromethane, chloroform, N, N-dimethylformamide (DMF). Good solubility in organic solvents provides convenience for its dispersion and reaction in organic synthesis reaction systems, enabling full contact of reactants, speeding up the reaction process and improving the reaction efficiency.
In addition, its density is about 1.4g/cm ³, which is of important reference value in terms of material ratio and volume calculation of reaction system.
It can be seen from the above that the many physical properties of 2-% cyano-4-trifluoromethylbenzonitrile play a crucial role in its application in the field of organic synthesis. The cooperation of different properties together determines its performance and use in various chemical reactions.
What are the precautions for storing and transporting 2-nitro-4-trifluoromethylbromobenzene?
2-% hydroxyl-4-trifluoromethylbenzonitrile is an important raw material for organic synthesis. Many precautions must be taken during storage and transportation.
It is active and sensitive to heat and vibration. Therefore, when storing, the first thing to control is temperature and humidity. It is advisable to choose a cool, dry and well-ventilated place, away from direct sunlight, to avoid decomposition or other chemical reactions caused by excessive temperature. The temperature should be maintained at 2-8 ° C, and the humidity should be controlled between 40% and 60%.
Furthermore, this substance is toxic and corrosive to a certain extent, and contact with the human body can cause harm. Store away from food, beverages and daily necessities, and have clear warning signs so that people know the danger. When handling, operators must wear appropriate protective equipment, such as protective clothing, gloves and goggles, to prevent contact with skin and eyes.
When transporting, there are also many precautions. Appropriate transportation methods and packaging materials should be selected according to their hazard characteristics. Pack in special chemical containers to ensure tight sealing and prevent leakage. During transportation, avoid severe vibration, collisions and high temperature environments. Transportation vehicles need to be equipped with corresponding emergency treatment equipment and protective equipment. In case of emergencies, they can respond in time.
In addition, whether it is storage or transportation, it is necessary to strictly abide by relevant regulations and standards, and keep detailed records, covering information such as warehousing time, quantity, storage conditions and transportation route. Once any abnormalities are found, such as damaged packaging, odor escape, etc., appropriate measures should be taken immediately to prevent the harm from expanding. In this way, the safety of 2-hydroxy-4-trifluoromethylbenzonitrile during storage and transportation is guaranteed.
What are the market prospects for 2-nitro-4-trifluoromethylbromobenzene?
2-% cyano-4-trifluoromethylbenzonitrile, which is used in the chemical industry, has a considerable prospect.
In today's chemical industry, fine chemicals are developing rapidly, and there is a growing demand for high-value-added fine chemicals in many fields. As a key organic synthesis intermediate, 2-% cyano-4-trifluoromethylbenzonitrile has important uses in many fields such as medicine, pesticides, and materials, so the market prospect is bright.
In the field of medicine, with the advancement of innovative drug research and development, the demand for special structure intermediates has increased greatly. 2-% cyano-4-trifluoromethylbenzonitrile has a unique chemical structure, which can introduce specific properties to drug molecules and improve drug activity, stability and selectivity. Many new anti-cancer and antiviral drugs can be seen in the research and development process, helping to create more efficient and low-toxicity drugs, so the demand in the field of pharmaceutical synthesis is expected to continue to grow.
The same is true in the field of pesticides. At present, high-efficiency, low-toxicity, and environmentally friendly pesticides are the mainstream of development. 2-% cyano-4-trifluoromethylbenzonitrile can be used to synthesize pesticides with novel mechanisms of action, enhancing the pesticide's killing power against pests and bacteria, and reducing the impact on the environment and non-target organisms. With the increasing emphasis on food safety and environmental protection, the market demand for such new pesticides will continue to rise, thus driving the expansion of the 2-% cyano-4-trifluoromethylbenzonitrile market.
The field of materials should also not be With the development of high-end industries such as electronic information and aerospace, the demand for high-performance materials has surged. 2% cyano-4-trifluoromethylbenzonitrile can participate in the synthesis of special engineering plastics, high-performance fibers and other materials, endowing the materials with excellent heat resistance, chemical stability and mechanical properties, and meeting the strict requirements of high-end industries for materials. Therefore, its market potential in the field of materials is huge.
However, although the market prospect is good, it also faces challenges. Production process complexity and cost control are the key. Optimizing the synthesis process, improving production efficiency and reducing production costs can enhance the market competitiveness of products. And under the pressure of environmental protection, it is necessary to ensure that the production process is green and sustainable, and meets environmental protection requirements.
Overall, 2-% cyano-4-trifluoromethylbenzonitrile has broad market prospects due to its wide use in many fields. With the development of various application fields, its market demand is expected to grow steadily. To occupy a favorable position in the market, companies need to continuously overcome technical problems and strengthen cost and environmental protection control.