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2-Methyl-4-Fluoro Nitrobenzene

2-Methyl-4-Fluoro Nitrobenzene

Hongda Chemical

Specifications

HS Code

224232

Chemical Formula C7H6FNO2
Molecular Weight 155.13
Appearance Liquid (usually)
Color Colorless to light yellow
Boiling Point Around 207 - 209 °C
Density Approx. 1.29 g/cm³
Solubility In Water Insoluble
Solubility In Organic Solvents Soluble in common organic solvents like ethanol, ether
Flash Point Around 84 °C
Vapor Pressure Low vapor pressure at room temperature
Odor Characteristic aromatic odor

As an accredited 2-Methyl-4-Fluoro Nitrobenzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

Packing & Storage
Packing 250 - gram bottle packaging for 2 - methyl - 4 - fluoro nitrobenzene chemical.
Storage 2 - methyl - 4 - fluoro nitrobenzene should be stored in a cool, dry, well - ventilated area away from heat sources and ignition sources. It should be kept in a tightly closed container, preferably made of corrosion - resistant materials. Store it separately from oxidizing agents, reducing agents, and other incompatible substances to prevent dangerous reactions.
Shipping 2 - methyl - 4 - fluoro nitrobenzene is shipped in tightly - sealed containers, typically drums. Due to its chemical nature, it's transported under hazardous goods regulations, ensuring proper handling and safety during transit.
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2-Methyl-4-Fluoro Nitrobenzene 2-Methyl-4-Fluoro Nitrobenzene
General Information
Historical Development
2 - Methyl - 4 - Fluoro Nitrobenzene is also a chemical substance. Its origin is the wonder of those who are new to research and develop, and they want new things to explore the unknown. People are exhausted of thinking, and in many times, there is no clue of this substance.
In the past, chemists used to be determined, and they did not use different methods of combining. Or because of the combination of raw materials, or because of the lack of parts, many setbacks have been made to obtain this 2 - Methyl - 4 - Fluoro Nitrobenzene. Its properties are clear, and its function is first revealed in the field of chemical synthesis.
In research, it is known that it can be used for general transformation, or in the synthesis of other things, or because of its special properties, it can be used as the basis for special materials. This is the unremitting exploration of predecessors, and gradually promoted, so that the exhibition of 2-Methyl-4-Fluoro Nitrobenzene can be used in the stage of transformation from micro to micro, and it can be used in world research.
Product Overview
Description of 2-methyl-4-fluoronitrobenzene
There is a substance called 2-methyl-4-fluoronitrobenzene. Its shape is also, at room temperature or liquid, color or light yellow, clear and has a special smell.
This substance is widely used in the chemical industry. It can be used as a key raw material for organic synthesis, and a variety of fine chemicals can be derived through clever reaction paths.
In terms of its physicochemical properties, it has a certain chemical activity. In the molecular structure, the synergy of methyl, fluorine atoms and nitro groups gives it a unique tendency to react. The strong electron-absorbing properties of nitro groups change the electron cloud density of the benzene ring, affecting the electrophilic substitution reaction activity; the introduction of fluorine atoms enhances its stability and special chemical properties.
However, this substance also needs to be treated with caution. Because of its toxicity and irritation, if it comes into contact with the human body, it may hurt the skin and mucous membranes, and damage health. When storing and using, when operating according to specifications, strictly observe safety principles to avoid hazards.
Physical & Chemical Properties
2-Methyl-4-Fluoro Nitrobenzene is an organic compound, which is quite unique in terms of its physical and chemical properties. Its color is light yellow, and it is a liquid at room temperature, with a special odor. The boiling point is about [X] ° C, and the melting point is about [X] ° C. This characteristic makes it stable in a specific temperature environment.
In terms of solubility, it is slightly soluble in water, but it can be miscible with many organic solvents, such as ethanol, ether, etc., due to the characteristics of the groups in the molecular structure. Its chemical properties are active, and the methyl, fluorine atoms and nitro groups on the benzene ring give it unique reactivity. Nitro has strong electron absorption, which reduces the electron cloud density of the benzene ring, and is prone to electrophilic substitution reactions, and is mostly in the nitro interposition. Methyl can make the electron cloud density of the ortho-para-position relatively increase, causing the reaction to have a selective check point. Fluorine atoms also affect the reactivity and selectivity because of their electronegativity. All these constitute the unique physicochemical properties of this compound.
Technical Specifications & Labeling
2-Methyl-4-fluoronitrobenzene is a chemical product developed by us. Its process specifications and identification (product parameters) are crucial.
In terms of process specifications, the synthesis method needs to be precisely controlled. With all kinds of raw materials, according to a specific ratio, temperature and duration, follow a rigorous process. During this time, the acid and alkali of the reaction environment and pressure should not be ignored. If there is a slight difference, the product will be impure.
In terms of identification (product parameters), the appearance needs to be a specific color state, and the impurity content must be limited to a very low level. The standard of purity is related to the wide range of uses and the quality. And its physical and chemical properties, such as melting point, solubility, etc., should be clearly marked so that users can use it as needed, and it can be used in various fields of industry and scientific research without error.
Preparation Method
To prepare 2-methyl-4-fluoronitrobenzene, the raw materials, production process, reaction steps and catalytic mechanism are as follows.
First take an appropriate amount of toluene, add a fluorine-containing catalyst in a specific reactor, and heat it at a controlled temperature to make it fluoride. 4-fluorotoluene can be obtained. This step requires precise temperature control to ensure that the reaction proceeds in the desired direction.
Then transfer 4-fluorotoluene to another reaction vessel, add a nitrifying agent, such as mixed acid (concentrated sulfuric acid and concentrated nitric acid are mixed in a certain proportion), and at a suitable temperature and time, a nitrification reaction occurs. During the reaction, closely monitor the temperature and reaction process to prevent side reactions from occurring.
In the whole process, catalyst activity, temperature and raw material ratio are all key. By optimizing each reaction condition and strictly controlling the process, the yield and purity of 2-methyl-4-fluoronitrobenzene can be improved to ensure stable and efficient production.
Chemical Reactions & Modifications
Recently, the chemical and reverse modification of 2-methyl-4-fluoronitrobenzene has been studied, and some results have been obtained.
The chemical and reverse modification of this compound is of great importance to our research. The method of the past may not be good. The method of reversing parts requires a lot of harsh strength and force, and the catalysis is not easy to obtain, resulting in an increase in the efficiency.
I thought deeply about the reason, and applied it to the catalysis. The new type of catalysis is used instead. This catalysis has the characteristics of high activity and high performance. It is also a good method to integrate and reverse the strength of the reaction.
With the newly obtained method, the required strength and force are reduced, and the catalysis is easy to obtain and durable. In terms of modification, the new method improves the efficiency and efficiency of the material. This is a major step in the research and development process, and it is expected to provide useful loans for the improvement of the current technology.
Synonyms & Product Names
Today there is a product called 2 - Methyl - 4 - Fluoro Nitrobenzene. This product is widely used in the field of chemical industry. Its synonymous names are also numerous. Or 2 - methyl - 4 - fluoronitrobenzene, which is named according to its chemical structure to explain its composition elements.
Or in the market, there are those who call it a chemical with a specific number, which is convenient for the industry. When merchants sell it, they often call it by this number, and everyone knows that it refers to this thing.
This 2 - Methyl - 4 - Fluoro Nitrobenzene has different synonyms, but it refers to the same substance. In chemical research and production, no matter what the name is, it is the same substance, and it is actually an indispensable species in the chemical industry.
Safety & Operational Standards
2-Methyl-4-fluoronitrobenzene is also one of the chemical substances. In its experimental preparation and application, safety and operating standards are of the essence.
Where the operation of this substance is involved, the experimenter must first check its physical and chemical properties. 2-Methyl-4-fluoronitrobenzene has a specific melting point, solubility, etc., which are the basis for operation. Only by knowing its properties can it be feasible and safe.
In the operating place, the ventilation equipment must be good. Because it may evaporate harmful gases, good ventilation can quickly discharge the turbid gas, so as not to cause harm to the experimenter by inhalation. And the operating table should be clean and tidy, and all kinds of appliances should be placed in an orderly manner to facilitate access and prevent confusion from causing errors.
When taking 2-methyl-4-fluoronitrobenzene, it is necessary to take the specification according to the precise quantity. The gauge must be clean and accurately calibrated to ensure that the dosage is correct. If the dosage is inaccurate, it will not only affect the experimental results, but also cause safety hazards due to overreaction.
During the reaction process, the temperature, pressure and other conditions are strictly set. The reaction of 2-methyl-4-fluoronitrobenzene may be sensitive to conditions. There is a slight error, or the reaction may be out of control, such as explosion and fire.
There are also rules for storing this thing. It should be placed in a cool, dry and well-ventilated place, away from fire and heat sources. Different chemicals are stored separately according to their characteristics to avoid danger caused by interaction.
After the experiment, the remaining 2-methyl-4-fluoronitrobenzene and related waste shall be disposed of according to the principles of environmental protection and safety. It should not be disposed of at will to prevent pollution of the environment and harm to all living beings.
In short, the safety and operation specifications of 2-methyl-4-fluoronitrobenzene are interlinked, which is related to the success or failure of the experiment and the safety of personnel. We must be cautious and not slack at all.
Application Area
2-Methyl-4-fluoronitrobenzene is also an organic compound. Its application field is quite wide. In the field of pharmaceutical synthesis, it can be used as a key intermediate to help many special drugs. With its special structure, it can introduce specific groups to make drugs have better curative effect and targeting.
In the field of pesticide creation, it also has its own shadow. It can be used to build a unique molecular structure to produce efficient and low-toxic pesticides, and agricultural protection products are free from pests and diseases.
And in the field of material science, or can participate in the preparation of special materials. With its reaction characteristics, the material is endowed with different properties, such as photoelectric properties, thermal stability, etc. Therefore, 2-methyl-4-fluoronitrobenzene has important application value in many fields and is indispensable for chemical research and production.
Research & Development
In recent years, Yu has devoted himself to the research of organic compounds, especially 2-Methyl-4-Fluoro Nitrobenzene. This substance has unique properties and has great potential in many fields.
At the beginning, its structure was analyzed, its characteristics were studied in detail, and the direction of synthesis was clarified. After repeated experiments, the existing method was improved, the reaction conditions were optimized, and the yield and purity were improved.
During this period, many problems were encountered, such as the complex by-products of the reaction, and the separation and purification were difficult. However, he was not discouraged. He searched the classics and asked Fang's family for advice, and finally found a way to solve the problem.
Today, significant progress has been made, the yield has steadily increased, and the quality is also good. However, the road of research and exploration is endless, and the future should continue to improve and expand its application field, hoping to contribute to the chemical, pharmaceutical and other industries and promote their development.
Toxicity Research
2-Methyl-4-fluoronitrobenzene is a chemical substance, and the study of its toxicity is quite important. Looking at the properties of this substance, its molecular structure is unique, or it contains the cause of toxicity. In the experiment, a white rat was used as a test, and this substance was administered to observe its reaction. See that the white rat gradually has abnormalities, slow movement, and less food, which shows that it is toxic. And analyze its impact on the environment. If it flows into the water source, it will be dangerous to pollute, and aquatic organisms will also suffer from it. Therefore, the study of its toxicity cannot be ignored. It is necessary to study its toxicology in detail, to understand the depth of its harm, and to make plans for protection and treatment, to ensure the safety of all living beings, and to protect the peace of the environment. This is the important task of our generation of chemical researchers.
Future Prospects
The future of this product, 2 - Methyl - 4 - Fluoro Nitrobenzene, is of great concern to our researchers. This compound, with its unique properties, has many possible applications.
Today's research has been studied, but there are still unfinished fields. We are still in the future, we can better understand the theory of its synthesis, making its synthesis method more precise, efficient and reliable. Or we can use new technologies, such as rice technology and colorization methods, to make it less energy consumption and less pollution.
Furthermore, this compound has great potential for application in materials science and engineering fields. Hope that we can uncover its secrets, use it to create new functional materials, or assist in the research of special effects, for the benefit of the world. In the future, the prospect of 2-Methyl-4-Fluoro Nitrobenzene is full of hope and challenge. We must aspire to research and explore it to uncover a new chapter.
Where to Buy 2-Methyl-4-Fluoro Nitrobenzene in China?
As a trusted 2-Methyl-4-Fluoro Nitrobenzene manufacturer, we deliver: Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements. Technical Excellence: Precision-engineered solutions backed by R&D expertise, from formulation to end-to-end delivery. Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.
Frequently Asked Questions

As a leading 2-Methyl-4-Fluoro Nitrobenzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

What are the main uses of 2-Methyl-4-Fluoro Nitrobenzene?
2-Methyl-4-fluoronitrobenzene is an important compound in organic chemistry. It has a wide range of main uses and is often a key intermediate in the synthesis of medicine. The methyl, fluorine atoms and nitro groups attached to the benzene ring give it unique chemical properties and can participate in various reactions to build complex drug molecular structures. For example, it may be used to prepare intermediates of specific antibiotics, through which it reacts with other reagents to gradually build the skeleton required for drugs.
In the field of pesticide creation, it also plays an important role. It can be prepared through a series of chemical transformations to produce high-efficiency, low-toxicity and environmentally friendly pesticides. Due to its specific structure, it may endow pesticides with unique biological activities, such as strong contact or stomach toxicity to some pests, but little toxicity to non-target organisms.
In the field of materials science, 2-methyl-4-fluoronitrobenzene is also useful. Can be used as a precursor for the synthesis of special functional materials. After chemical modification and polymerization, it is expected to prepare materials with unique electrical, optical or thermal properties. For example, it is used in the synthesis of organic Light Emitting Diode (OLED) materials, which contribute to the improvement of their luminous efficiency and stability.
In addition, in the fine chemical industry, it is often used as a raw material for the synthesis of various fine chemicals. Such as the preparation of special fragrances, dyes and additives. Due to its structural characteristics, it can give products a unique color, smell, or other functional characteristics, thus meeting the specific needs of fine chemicals in different fields.
What are the physical properties of 2-Methyl-4-Fluoro Nitrobenzene?
2-Methyl-4-fluoronitrobenzene is one of the organic compounds. Its physical properties are particularly important and related to various chemical applications.
Looking at its properties, under normal temperature and pressure, it is mostly colorless to light yellow liquid, which can be used for preliminary identification. Its odor is also characteristic, often irritating, and its chemical activity can be known by smelling.
The boiling point is about a specific temperature range. The one that covers the boiling point is related to its phase transition under different temperature conditions. According to many experimental measurements, its boiling point can cause the substance to change from liquid to gaseous state. This temperature is crucial in separation and purification processes.
Melting point is also an important physical property. The melting point of 2-methyl-4-fluoronitrobenzene determines its form in a low temperature environment. When the temperature drops below the melting point, the substance gradually solidifies from a liquid state to a solid state.
The value of density characterizes the mass of the substance per unit volume. 2-methyl-4-fluoronitrobenzene has a fixed density. In the process of mixing and blending, it can be accurately measured according to it to ensure that the proportion of the reaction material is appropriate.
In terms of solubility, its solubility in organic solvents is acceptable, but it is not good in water. This characteristic can be used in extraction and separation operations to select a suitable solvent to effectively separate the target substance from the impurities.
The refractive index is also one of its physical properties. When light passes through the substance, the degree of refraction has a specific value, which can assist in the identification of the purity of the substance and is also an important parameter for the study of its optical properties.
The above physical properties are all necessary knowledge for the study and application of 2-methyl-4-fluoronitrobenzene. In many fields such as chemical synthesis, drug research and development, material preparation, etc., these physical properties are relied on for the regulation of construction technology and quality control.
What are the chemical properties of 2-Methyl-4-Fluoro Nitrobenzene?
2-Methyl-4-fluoronitrobenzene is also an organic compound. Its properties have many characteristics, which are related to chemical properties and are quite important.
In this compound, the nitro group is a strong electron-absorbing group, the fluorine atom has a certain electronegativity, and the methyl group is the electron-donating radical. The presence of nitro groups decreases the electron cloud density of the benzene ring, decreases the electrophilic substitution activity of the benzene ring, and decreases the density of the adjacent and para-potential electron clouds, especially. Although fluorine atoms are highly electronegative, they can conjugate with the benzene ring to a certain extent due to their lone pair of electrons, which also affects the electron cloud distribution of the benzene ring. The action of methyl donators slightly increases the electron cloud density of the benzene ring to a certain extent, but its effect is weaker than that
In terms of reactivity, 2-methyl-4-fluoronitrobenzene can be involved in many reactions. In the nucleophilic substitution reaction, the nitro activates the benzene ring, so that the halogen atom or other leaving groups are easily replaced by nucleophilic reagents. In case of nucleophilic reagents, the halogen atom can be replaced. This is because the electron-absorbing nitro causes the electron cloud density of the benzene ring to decrease, which is conducive to the attack of nucleophilic reagents.
In the reduction reaction, the nitro group can be reduced to an amino group. Common reducing agents such as iron and hydrochloric acid, tin and hydrochloric acid can achieve this change. After a series of reactions, the nitro group finally forms an amino group, and a new
In addition, the spatial structure and reaction selectivity of the compound are also affected due to the steric resistance and electronic effect of methyl and fluorine atoms. Under different reaction conditions, it can exhibit unique reaction paths and product distributions. In conclusion, the chemical properties of 2-methyl-4-fluoronitrobenzene are determined by their functional groups and interactions, and have various applications and reaction characteristics in the field of organic synthesis.
What are the synthesis methods of 2-Methyl-4-Fluoro Nitrobenzene?
The common methods for synthesizing 2-methyl-4-fluoronitrobenzene are as follows.
One is to use 2-methyl-4-fluoronitrobenzene as the starting material. The diazonium salt is formed by diazotization reaction with sodium nitrite and dilute sulfuric acid at low temperature. This process requires careful temperature control to prevent the decomposition of the diazonium salt. Then, the diazonium salt and the nitrite are reacted under specific conditions, so that the amino group can be replaced by the nitro group to obtain 2-methyl-4-fluoronitrobenzene. The key to this method is to control the conditions of the diazotization reaction. The temperature and the proportion of reactants have a great influence on the reaction.
The second is to use 2-methyl-4-fluorobenzene as the raw material. It is first nitrified. Generally, mixed acid (a mixture of concentrated sulfuric acid and concentrated nitric acid) is used as the nitrifying reagent. At a suitable temperature and reaction time, nitro groups will be introduced into the benzene ring. However, this reaction requires attention to regioselectivity, because the original methyl and fluorine atoms on the benzene ring will guide the introduction position of nitro groups. In order to increase the yield of the target product, the reaction can be optimized by adjusting the ratio of mixed acid, reaction temperature and time.
The third can be started from 2-methyl-4-halogenated nitrobenzene. If the halogen atom is chlorine or bromine, the halogen exchange reaction can be carried out with fluoride. For example, using fluorine sources such as potassium fluoride, in the presence of appropriate solvents and catalysts, halogen atoms can be replaced by fluorine atoms to obtain 2-methyl-4-fluoronitrobenzene. In this reaction, the choice of solvent is very important, which needs to be able to dissolve the reactants and have a certain solubility to fluoride, and the catalyst can speed up the reaction rate and improve the reaction efficiency.
All synthetic methods have their own advantages and disadvantages. In practical application, the most suitable method should be selected according to the comprehensive consideration of factors such as the availability of raw materials, cost, and difficulty of reaction conditions.
What to pay attention to when storing and transporting 2-Methyl-4-Fluoro Nitrobenzene
2-Methyl-4-fluoronitrobenzene is an organic compound. When storing and transporting it, the following numbers should be paid attention to:
First, the storage place should be cool and well ventilated. This compound is easy to decompose when heated, or even cause the risk of combustion and explosion. Therefore, it should be kept away from fire and heat sources, and the warehouse temperature should be controlled within an appropriate range, not too high.
Second, it must be stored in isolation from oxidizing agents, reducing agents, alkalis, etc. 2-methyl-4-fluoronitrobenzene is prone to chemical reactions with the above substances, which may cause dangerous conditions. Therefore, it is necessary to ensure that it is stored separately to avoid the possibility of cross-contamination.
Third, the storage container must be tightly sealed. This compound is volatile, and poor sealing can easily cause it to evaporate into the air, which is not only wasted, but also pollutes the environment and is harmful to human health. At the same time, sealed containers can also prevent the intrusion of impurities such as moisture, so as not to affect its quality.
Fourth, when transporting, ensure that the container is stable and free of leakage. Transportation vehicles should be equipped with corresponding fire equipment and leakage emergency treatment equipment to prevent accidents. The loading and unloading process must be handled with care to avoid collisions and heavy pressure to prevent damage to the container.
Fifth, operators should take protective measures. When storing and transporting operations, operators should wear suitable protective clothing, gloves and protective glasses to avoid direct contact with the compound. If they accidentally come into contact, they should immediately deal with it in the correct way. In conclusion, the storage and transportation of 2-methyl-4-fluoronitrobenzene must be carried out in strict accordance with relevant regulations and safety guidelines to ensure the safety of personnel and the environment.