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2-Methyl-3-(Trifluoromethyl)Nitrobenzene

2-Methyl-3-(Trifluoromethyl)Nitrobenzene

Hongda Chemical

    Specifications

    HS Code

    882662

    Chemical Formula C8H6F3NO2
    Molar Mass 205.134 g/mol
    Appearance Liquid (usually)
    Boiling Point Around 220 - 225 °C
    Solubility In Water Low solubility, organic - soluble
    Vapor Pressure Low at room temperature
    Odor Typical organic aromatic odor

    As an accredited 2-Methyl-3-(Trifluoromethyl)Nitrobenzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing 250g of 2 - methyl - 3 - (trifluoromethyl)nitrobenzene in a tightly - sealed glass bottle.
    Storage 2 - methyl - 3 - (trifluoromethyl)nitrobenzene should be stored in a cool, dry, well - ventilated area. Keep it away from heat sources, open flames, and oxidizing agents. Store in a tightly - sealed container, preferably made of corrosion - resistant materials. Label clearly to prevent misidentification. Avoid storing near food or beverages due to its potential toxicity.
    Shipping 2 - methyl - 3 - (trifluoromethyl)nitrobenzene should be shipped in well - sealed, corrosion - resistant containers. Label packages clearly with relevant hazard warnings. Ship via carriers compliant with chemical transportation regulations to ensure safe transit.
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    2-Methyl-3-(Trifluoromethyl)Nitrobenzene 2-Methyl-3-(Trifluoromethyl)Nitrobenzene
    General Information
    Historical Development
    2-Methyl-3- (trifluoromethyl) nitrobenzene is also an organic compound. It began in the process of chemical research. At the beginning, scholars were exploring the properties and systems of various compounds, and gradually came into contact with it.
    At that time, the chemical technology was not as sophisticated as it is today, and it was quite laborious to analyze this compound. However, many scholars worked tirelessly to test it with various methods to understand its nature and structure.
    Years have passed, science and technology have advanced day by day, and research has deepened. In the synthesis method, there have been many new innovations, and the yield and purity have been improved. Its application in chemical, pharmaceutical and other fields is gradually becoming known. The history of 2-methyl-3 - (trifluoromethyl) nitrobenzene is a bright color in the long volume of chemical development.
    Product Overview
    Today there is a substance called 2-methyl-3- (trifluoromethyl) nitrobenzene. This substance is an important raw material for organic synthesis and has unique properties. Looking at its structure, methyl and trifluoromethyl are combined on the benzene ring, and nitro groups are also attached to it.
    2-methyl-3- (trifluoromethyl) nitrobenzene, which is often a colorless to light yellow liquid with a special odor. It has a wide range of uses in the chemical industry and is often a key intermediate in the synthesis of fine chemicals. With its structural properties, it can participate in many chemical reactions and provide a path for the preparation of other organic compounds.
    In the reaction, because it contains nitro and specific substituents, it can show unique chemical activity, or participate in nucleophilic substitution, or involve reduction reactions, which are all important links in organic synthesis. In the process of chemical industry development, the value of 2-methyl-3- (trifluoromethyl) nitrobenzene has become increasingly prominent, laying the foundation for the birth of many chemical products.
    Physical & Chemical Properties
    Today there is a thing called 2 - Methyl - 3 - (Trifluoromethyl) Nitrobenzene. Its properties are related to the quality of physical and chemical. Look at its shape, or liquid, color or transparent, or slightly colored. Its taste, or has a special smell. Regarding its boiling point, it is in a specific temperature range due to intermolecular forces to maintain the balance of gas and liquid. As for the melting point, it is also determined by its structure. At low temperatures, it condenses into a solid state. Its solubility varies in different solvents, according to the principle of similar compatibility, or soluble in organic solvents, but insoluble in water. Its chemical activity, due to the presence of nitro, methyl and trifluoromethyl groups, is easy to initiate various reactions, such as nucleophilic substitution and redox. This is a summary of its physical and chemical properties.
    Technical Specifications & Labeling
    Today there is 2 - Methyl - 3 - (Trifluoromethyl) Nitrobenzene, which is very important in the process specification and identification (product parameters). Its process specification requires the ratio of materials and reaction conditions to be clear. In the material, the proportion of various ingredients is accurate, which is related to the purity of the product. When reacting, the temperature, pressure and duration are all fixed, and there should be no slight difference.
    As for the identification (product parameters), the properties, purity, impurity content, etc. of the product should be listed in detail. The properties need to be clear about their color, state and taste, so that people can know at a glance. The purity is directly related to the quality and must be determined by an accurate method. The impurity content cannot be ignored, and it needs to be clearly marked to comply with the specifications, ensure the high quality of the product, and be trusted by the user. In this way, the way to meet the process specifications and identification (product parameters) is also.
    Preparation Method
    The method of preparing 2-methyl-3- (trifluoromethyl) nitrobenzene is related to the raw materials and production process, reaction steps and catalytic mechanism.
    Take appropriate raw materials, such as benzene compounds containing methyl groups and trifluoromethyl groups. In the reactor, control its temperature and pressure, and apply a specific catalyst. This catalyst can promote the rate of reaction, change the route of chemical reaction, and reduce its activation energy.
    First, the benzene substrate meets the nitrogenation reagent, and the reaction is carried out in an orderly manner according to a certain reaction step. In the initial stage, the raw material molecules collide with each other, and the active parts are combined with each other through the action of the catalyst. The nitro group gradually replaces the specific hydrogen atom on the benzene ring, and after multiple intermediate reactions, the final product is 2-methyl-3- (trifluoromethyl) nitrobenzene.
    The production process needs to be precisely controlled, and the time, temperature and proportion of reactants of each reaction step are all critical. After the reaction, the pure product is obtained by separation and purification, which can meet the needs of industry or scientific research.
    Chemical Reactions & Modifications
    Yu has dedicated himself to the research of chemical products, and is particularly interested in 2-Methyl-3- (Trifluoromethyl) Nitrobenzene. Its chemical reaction and modification are related to many chemical keys. Yu has been studying for a long time and has a lot of experience.
    The beauty of covering chemical reactions lies in precise regulation, so that substances can be changed according to our intentions. The reaction of 2-Methyl-3- (Trifluoromethyl) Nitrobenzene, or the genus of substitution and addition, requires detailed consideration of reaction conditions, such as temperature, pressure, and the type and dosage of catalysts. If there is a slight difference, the results are very different.
    As for modification, it is the important way to optimize its performance. The transformation of functional groups or the fine-tuning of the structure can be used to meet different needs. Or to increase its stability, or to change its solubility, all depend on fine design and practice.
    I am more than just doing things, thinking about it day and night, hoping to make breakthroughs, and make a small contribution to the refinement of chemical products. Expect to achieve remarkable results in the future and benefit the world.
    Synonyms & Product Names
    2-Methyl-3- (trifluoromethyl) nitrobenzene is an important compound in the field of chemical synthesis. Its nickname and trade name also have various expressions in the industry.
    In the past, Fang family first came into contact with this substance and explored its properties in a unique way. In many ancient books, it may be called "synonymous methylfluoronitrobenzene", which is derived from the characteristics of methyl group, fluoromethyl group and nitro group in its molecular structure, according to the naming rules of that time. There is also a trade name, called "Ruifu Nitrate", because a trade name focuses on the research and development of this product, so it is named by the trade name, hoping to recognize its uniqueness.
    Looking at today's world, chemical refinement, this thing is widely used. However, its alias and trade names still carry the lingering charm of the past, and are well known to researchers. In literature and research, its name can be heard to distinguish its quality, adding a unique color to the road of chemical inquiry.
    Safety & Operational Standards
    2-Methyl-3- (trifluoromethyl) nitrobenzene safety and operation specifications
    Fu 2-methyl-3- (trifluoromethyl) nitrobenzene, chemical products are also. It is widely used in the chemical industry, but it also has certain dangers. Therefore, it is essential to know its safety and operation specifications.
    #1. Storage rules
    This product should be stored in a cool and ventilated warehouse. Keep away from fire and heat sources, and the warehouse temperature should not exceed 30 ° C. It should be stored separately from oxidants, reducing agents, and alkalis, and should not be mixed. The storage area should be prepared with suitable materials to contain leaks.
    #2. The essentials of transportation
    When transporting, make sure that the container does not leak, collapse, fall or damage. During transportation, it is necessary to prevent exposure to the sun, rain and high temperature. The tank (tank) car used during transportation should have a grounding chain, and holes can be set in the tank to reduce shock and generate static electricity. It is strictly forbidden to mix and transport with oxidants, reducing agents, alkalis, edible chemicals, etc. During transportation, it should be driven according to the specified route, and do not stop in residential areas and densely populated areas.
    #3. Operation methods
    Operators must undergo special training and strictly abide by the operating procedures. It is recommended that operators wear self-priming filter gas masks (half masks), chemical safety glasses, anti-poison penetration work clothes, and rubber oil-resistant gloves. When operating, keep away from fires and heat sources, and smoke is strictly prohibited in the workplace. Use explosion-proof ventilation systems and equipment. Prevent steam from leaking into the air of the workplace. Avoid contact with oxidants, reducing agents, and alkalis. When handling, pack and unload lightly to prevent damage to packaging and containers. Equip with corresponding varieties and quantities of fire-fighting equipment and leakage emergency treatment equipment. Empty containers may remain harmful substances.
    The safety and operation specifications for Fu 2-methyl-3- (trifluoromethyl) nitrobenzene are related to personnel safety, environmental integrity and smooth production. All practitioners should follow them carefully and not slack off.
    Application Area
    2-Methyl-3- (trifluoromethyl) nitrobenzene, this chemical substance, the application field is very critical. In the field of pharmaceutical synthesis, it can be used as an important intermediate to help create new specific drugs, which is expected to cure many difficult diseases and bring good news to patients. In the field of materials science, it can participate in the preparation of high-performance materials, so that the materials have unique electrical and optical properties, and are used in advanced electronic devices and optical instruments to improve product performance and quality. In addition, in the fine chemical industry, it is also an indispensable raw material, which can be derived from various high-value-added fine chemicals, such as special dyes and fragrances, to meet the needs of multiple markets and promote the vigorous development of the fine chemical industry. Its application in many fields is like a shining star, illuminating the way forward for chemical research and industrial development.
    Research & Development
    Modern chemistry has been refined, and categories have proliferated. I focus on the research of 2-methyl-3- (trifluoromethyl) nitrobenzene, which has unique properties and is widely used.
    At the beginning, its structure was analyzed, its properties were identified, and the reaction mechanism was studied in detail. During the experiment, there may be difficulties, the yield did not meet expectations, and impurities were also disturbed. However, I have a firm heart, repeated and easier conditions, and finally obtained.
    After long-term research, the synthesis path was optimized, and the yield and purity were improved. Looking at its development, there may be major breakthroughs in the fields of medicine and materials in the future. I should continue to forge ahead, hoping to expand its new territory, enhance its brilliance in the path of chemistry, benefit people's livelihood, and promote the advancement of science and technology.
    Toxicity Research
    2 - Methyl - 3 - (Trifluoromethyl) Nitrobenzene is an organic compound, and its toxicity research is crucial. I have been studying the toxicity of this substance for a long time. Looking at its structure, the existence of fluorine atoms and nitro groups may cause unique toxic effects.
    After experimental investigation, in animal experiments, if the substance enters the organism, it may affect the normal function of the liver and kidneys. The biochemical indicators of the liver of the infected animals are different, and the metabolism is disturbed. And it also has effects on the nervous system, causing abnormal behavior.
    From the molecular level, or in combination with key proteins in the body, it interferes with normal physiological processes. Although the full mechanism of toxicity has not yet been clarified, it has been confirmed that it has certain toxicity. In the future, more rigorous experiments and in-depth investigations should be conducted to clarify the full picture of its toxicity, providing a solid basis for preventing its harm and protecting the environment and human health.
    Future Prospects
    The future prospects are related to 2-methyl-3- (trifluoromethyl) nitrobenzene, which has considerable prospects in the field of chemical industry. Looking at today, science and technology are changing day by day, and research is not limited. In the future, it may be possible to find a simpler, more efficient and environmentally friendly way to reduce energy consumption, reduce pollution, and meet the concept of green chemistry.
    Furthermore, its application scope may be expanded. In materials science, or as a key component in the creation of novel functional materials, give materials unique properties, such as excellent stability and special optical properties. In the field of medicine, through in-depth research, it may be able to reveal its potential medicinal value, provide an opportunity for the development of new drugs, and solve the disease of patients.
    Our generation of chemical researchers, with an enterprising heart, should make unremitting research to inspire the future brilliance of 2-methyl-3- (trifluoromethyl) nitrobenzene, and do their best for the prosperity of chemistry and the progress of society.
    Where to Buy 2-Methyl-3-(Trifluoromethyl)Nitrobenzene in China?
    As a trusted 2-Methyl-3-(Trifluoromethyl)Nitrobenzene manufacturer, we deliver: Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements. Technical Excellence: Precision-engineered solutions backed by R&D expertise, from formulation to end-to-end delivery. Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.
    Frequently Asked Questions

    As a leading 2-Methyl-3-(Trifluoromethyl)Nitrobenzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

    What are the main uses of 2-Methyl-3- (Trifluoromethyl) Nitrobenzene?
    2-Methyl-3- (trifluoromethyl) nitrobenzene is also an organic compound. It has a wide range of uses and is used in various fields of chemical industry.
    First, it is often an important intermediate in the synthesis of medicine. With its special chemical structure, it can be derived from compounds with specific pharmacological activities through many chemical reactions. For example, through carefully designed reaction steps, it can be converted into pharmaceutical ingredients that have curative effects on specific diseases, opening up avenues for pharmaceutical research and development, and helping to create novel drugs to heal patients.
    Second, it is also of key value in the creation of pesticides. With this as the starting material, many high-efficiency, low-toxicity and environmentally friendly pesticide varieties can be prepared by chemical synthesis. Such pesticides can effectively prevent and control crop diseases and pests, ensure the healthy growth of crops, improve the yield and quality of crops, and contribute greatly to the stability and development of agricultural production.
    Third, in the field of materials science, it also shows its unique use. It can participate in the synthesis of special functional materials, such as some materials with special optical and electrical properties. By ingeniously combining with other compounds, the material is endowed with unique properties, meeting the needs of electronics, optics and other industries for special materials, and promoting technological innovation and progress in related fields. In conclusion, although 2-methyl-3- (trifluoromethyl) nitrobenzene is an organic compound, it plays an important role in many important fields such as medicine, pesticides, and materials, providing key support for the development of many industries.
    What are the physical properties of 2-Methyl-3- (Trifluoromethyl) Nitrobenzene?
    2-Methyl-3- (trifluoromethyl) nitrobenzene is an important compound in organic chemistry. Its physical properties are unique and it has key uses in many fields.
    When it comes to appearance, under normal temperature and pressure, 2-methyl-3- (trifluoromethyl) nitrobenzene is often colorless to light yellow liquid, clear and translucent, and has no obvious suspended solids. This appearance feature is easy to identify in actual operation and observation.
    Looking at its melting point, the melting point of this compound is low, about -30 ° C. The low melting point allows it to melt into a liquid state under relatively mild conditions. This property is crucial for some chemical reactions that require low-temperature melting operations, because it can avoid adverse effects of high temperature on the structure and properties of the compound.
    In terms of boiling point, the boiling point of 2-methyl-3- (trifluoromethyl) nitrobenzene is about 220-230 ° C. A higher boiling point indicates that the compound has good thermal stability, and the gasification transition occurs at relatively high temperatures. This is extremely important when it needs to be separated and purified by means of distillation, because it can maintain the liquid state at higher temperatures, which is convenient for separation from other substances with large differences in boiling points.
    The density is about 1.35-1.45 g/cm ³, which is denser than water, so it will sink to the bottom when mixed with water. This property can be used as an important basis when involving liquid-liquid separation operations.
    Solubility is also one of the important physical properties. 2-Methyl-3 - (trifluoromethyl) nitrobenzene is insoluble in water, but soluble in common organic solvents such as ethanol, ethyl ether, dichloromethane, etc. This solubility characteristic allows it to be used as a reactant or product in organic synthesis. When used as a reactant or product, a suitable organic solvent can be selected for dissolution and reaction according to different needs, and it is also easy to separate from the reaction system by extraction and other means.
    In addition, 2-methyl-3- (trifluoromethyl) nitrobenzene also has a certain volatility. Although the volatility is not strong, some of them will still evaporate into the air under open system or heating conditions. Therefore, during storage and use, attention should be paid to sealing operations to prevent losses and environmental pollution caused by volatilization.
    These physical properties of 2-methyl-3- (trifluoromethyl) nitrobenzene are interrelated and jointly determine their application mode and scope in organic synthesis, chemical production and other fields. In practical application, it is of great significance to fully understand and rationally utilize these properties to achieve efficient and safe production and research work.
    Is 2-Methyl-3- (Trifluoromethyl) Nitrobenzene Chemically Stable?
    The chemical stability of 2-methyl-3- (trifluoromethyl) nitrobenzene is related to many aspects. This compound contains nitro and trifluoromethyl groups. The nitro group has strong electron-absorbing properties, which can reduce the electron cloud density of the benzene ring, making the benzene ring more vulnerable to attack by nucleophiles, which may damage its stability. Trifluoromethyl is also a strong electron-absorbing group, which will strengthen the effect of reducing the electron cloud density of the benzene ring, or make the compound more active and less stable.
    However, the stability does not depend only on the electronic effect of the group. The steric resistance of its molecular structure also affects it. 2 - A is based on the specific position of the benzene ring, or due to the steric barrier, the reaction reagent is blocked from approaching the benzene ring, and in some reactions, the stability of the compound may be improved.
    Furthermore, external conditions have a great influence on its stability. In high temperature environments, the thermal motion of molecules intensifies, the energy of chemical bonds increases, or the compound is more prone to chemical reactions, and the stability decreases. In case of a specific solvent, if it interacts with the compound, such as the formation of hydrogen bonds or other intermolecular forces, or changes its stability.
    In common chemical environments, the strong electron-absorbing properties of 2-methyl-3- (trifluoromethyl) nitrobenzene nitro and trifluoromethyl are relatively active, and the stability is inferior to that of compounds without such strong electron-absorbing groups on the benzene ring. However, under specific conditions, such as low temperature, no active reagent environment, and spatial steric resistance, it can also maintain a certain stability. In short, its stability cannot be generalized, and it needs to be judged according to the specific environment and reaction conditions.
    What are the synthesis methods of 2-Methyl-3- (Trifluoromethyl) Nitrobenzene?
    The synthesis method of 2-methyl-3- (trifluoromethyl) nitrobenzene is ancient, and it is detailed for you today.
    First, 2-methyl-3-trifluoromethylaniline is used as the starting material and can be obtained by diazotization and nitrification. Dissolve 2-methyl-3-trifluoromethylaniline in an appropriate amount of acid, such as hydrochloric acid or sulfuric acid, and add sodium nitrite solution dropwise at low temperature to carry out diazotization reaction to generate diazonium salts. This process requires strict temperature control to prevent the decomposition of diazonium salts. Then, the diazonium salt solution is slowly dropped into the nitrifying reagent containing nitrite, such as the mixture of sodium nitrite and sulfuric acid. After the substitution reaction, the nitro group replaces the diazonium group, and then obtains 2-methyl-3- (trifluoromethyl) nitrobenzene.
    Second, with 2-methyl-3-trifluoromethylbenzene as raw material, nitrate first, and then methylate. Put 2-methyl-3-trifluoromethylbenzene in a suitable solvent, such as dichloromethane, add a nitrifying reagent, such as mixed acid (a mixture of nitric acid and sulfuric acid), and react at a suitable temperature to introduce nitro groups on the benzene ring. Then, methylating reagents, such as iodomethane and alkali (such as potassium carbonate), are used to introduce methyl groups at specific positions in the benzene ring under appropriate reaction conditions to synthesize the target product.
    Third, the corresponding halogenated aromatic hydrocarbons are used as raw materials, and the metal-catalyzed coupling reaction is carried out. 2-Halo-3- (trifluoromethyl) nitrobenzene containing halogen atoms (such as chlorine, bromine, iodine) is selected. In the presence of metal catalysts (such as palladium catalysts) and ligands, the coupling reaction occurs with methylating reagents under the action of suitable solvents and bases to achieve the introduction of methyl groups and obtain 2-methyl-3- (trifluoromethyl) nitrobenzene. This method requires fine control of the reaction conditions to achieve good yield and selectivity.
    All synthesis methods have their own advantages and disadvantages, and must be selected according to the availability of raw materials, the difficulty of reaction conditions, and the purity of the product.
    What are the precautions for 2-Methyl-3- (Trifluoromethyl) Nitrobenzene during storage and transportation?
    2-Methyl-3- (trifluoromethyl) nitrobenzene is an organic compound. When storing and transporting, pay attention to the following matters:
    First, when storing, find a cool, dry and well-ventilated place. This substance is easy to decompose when heated. If stored in a high temperature environment, it may be dangerous, so the temperature should be controlled in an appropriate range, away from heat and fire sources. Because it is an organic substance, it is flammable, and it is extremely critical to prevent fire in case of open flame or hot topic, or cause combustion or even explosion.
    Second, it should be stored separately from oxidants, reducing agents, acids, bases, etc., and must not be mixed. This compound is chemically active, comes into contact with the above substances, or causes violent chemical reactions, and even endangers safety. And it is necessary to ensure that the storage container is well sealed to prevent leakage. Because of its fluorine, nitro and other groups, it is also harmful to the human body after leakage or polluting the environment.
    Third, when transporting, it is necessary to strictly follow the relevant regulations and standards. Select suitable means of transportation, and the transportation equipment should have the functions of anti-leakage, fire prevention, explosion protection, etc. During transportation, it is necessary to pay close attention to changes in environmental factors such as temperature and humidity to avoid violent vibration and collision to prevent leakage caused by package damage.
    Fourth, personnel engaged in storage and transportation must undergo professional training and be familiar with the characteristics, hazards and emergency treatment methods of the substance. In the event of a leak or other accident, emergency measures should be taken quickly and correctly, such as evacuating personnel, sealing off the site, plugging and cleaning, etc., to reduce the harm.
    In conclusion, 2-methyl-3- (trifluoromethyl) nitrobenzene has strict requirements during storage and transportation, from environmental conditions, storage of items, to personnel operation, etc., so as to ensure the safety of the entire process.