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2-Methyl-1-Nitro-4-Trifluoromethyl-Benzene

2-Methyl-1-Nitro-4-Trifluoromethyl-Benzene

Hongda Chemical

    Specifications

    HS Code

    296887

    Chemical Formula C8H6F3NO2
    Molecular Weight 205.13
    Appearance Liquid (usually)
    Boiling Point Around 200 - 210 °C
    Melting Point Data may vary, typically low
    Density Approx. 1.3 - 1.4 g/cm³
    Solubility In Water Low solubility
    Solubility In Organic Solvents Soluble in common organic solvents
    Vapor Pressure Low at room temperature
    Flash Point Data varies, but potentially flammable

    As an accredited 2-Methyl-1-Nitro-4-Trifluoromethyl-Benzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing 250g of 2 - methyl - 1 - nitro - 4 - trifluoromethyl - benzene packaged in a sealed glass bottle.
    Storage Store 2 - methyl - 1 - nitro - 4 - trifluoromethyl - benzene in a cool, dry, well - ventilated area. Keep it away from heat sources, open flames, and oxidizing agents. It should be stored in a tightly - sealed container, preferably made of corrosion - resistant materials, to prevent leakage and potential reactions with air or moisture.
    Shipping 2 - methyl - 1 - nitro - 4 - trifluoromethyl - benzene, a potentially hazardous chemical, must be shipped in accordance with strict regulations. Use appropriate, secure containers to prevent leakage. Ensure proper labeling indicating its nature for safe transport.
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    2-Methyl-1-Nitro-4-Trifluoromethyl-Benzene 2-Methyl-1-Nitro-4-Trifluoromethyl-Benzene
    General Information
    Historical Development
    In the field of chemistry, the development of 2 - Methyl - 1 - Nitro - 4 - Trifluoromethyl - Benzene has a rich history. In the past, chemists have explored the way of organic synthesis, and they have tried and repeated studies to reach this compound. At first, due to limited analytical methods, the understanding of its structure is still shallow, and only a little knowledge of its methyl, nitro and trifluoromethyl groups is known. However, with the passage of time, analytical techniques have become more and more refined, and spectroscopy, mass spectrometry and other techniques have been gradually used to clarify its exact structure. At that time, the synthesis method has also evolved, from a complicated and inefficient method at the beginning, to a simpler and more efficient method. Chemists uphold the spirit of research and relentlessly explore the optimization path, making this compound from little known. As for its emergence in many fields today, its historical development is a vivid portrayal of the process of chemical exploration.
    Product Overview
    2-Methyl-1-nitro-4-trifluoromethylbenzene is the chemical substance I studied. This substance is unique. Its shape is [specific state, need to be supplemented according to the actual situation], and its color is [color, need to be supplemented according to the actual situation]. In its structure, methyl, nitro and trifluoromethyl are cleverly connected to the benzene ring, causing it to have a unique chemical activity.
    In the reaction, due to its specific group, it can exhibit unique reactivity. Or under specific conditions, it can react with [list the substances that may react, need to be supplemented according to the actual situation] to achieve a specific transformation. Its physical properties are also worthy of attention. The melting point is about [specific melting point, need to be supplemented according to the actual situation], and the boiling point is between [specific boiling point range, need to be supplemented according to the actual situation].
    This substance may have potential uses in many fields, such as in [list possible application fields, need to be supplemented according to the actual situation], or can be used as a key raw material to help the development of related industries. We should continue to study to understand its more characteristics and applications, and contribute to the development of chemistry.
    Physical & Chemical Properties
    2 - Methyl - 1 - Nitro - 4 - Trifluoromethyl - Benzene is an organic compound whose physicochemical properties are worth exploring. Looking at its physical properties, under normal conditions, this substance may be in a liquid state with a specific color and odor. Its boiling point and melting point are also key characteristics. The boiling point is related to the temperature at which it changes from liquid to gas, and the melting point is related to the temperature at which the solid state changes to liquid state. These properties are affected by intermolecular forces.
    In terms of chemical properties, nitro, methyl and trifluoromethyl in this compound all have unique reactivity. Nitro groups have strong oxidizing properties and can participate in reduction reactions; methyl groups can perform substitution reactions; trifluoromethyl groups, because of their strong electron absorption, will affect the electron cloud density of benzene rings, and then affect the electrophilic substitution reaction activity of compounds. These physicochemical properties have important applications and research values in organic synthesis, materials science and other fields.
    Technical Specifications & Labeling
    There is a product today called 2 - Methyl - 1 - Nitro - 4 - Trifluoromethyl - Benzene. To determine its technical regulations and identification (commodity parameters), it should be discussed as follows.
    The technical regulations of this product need to be clear about the selection of its raw materials, and carefully selected to maintain purity. In the process, temperature, pressure, etc. need to be precisely controlled. If there is a slight difference, the quality will be difficult to guarantee. The reaction time is also the key. Do it in sequence. Don't be impatient.
    As for the identification (commodity parameters), its characteristics need to be detailed, and the color, taste and shape are all available. Measure its purity, the higher the quality, the better. Remember its molecular weight, melting point, boiling point, etc., one by one, it is a qualified mark. In this way, this product can be suitable for the needs and used correctly.
    Preparation Method
    To prepare 2 - Methyl - 1 - Nitro - 4 - Trifluoromethyl - Benzene, take the raw material first. Based on toluene, it has a stable aromatic ring and can be the basis for the reaction. Add a trifluoromethylation reagent, such as trifluoromethyl halide, and under appropriate catalysis, let trifluoromethyl into the toluene ring to obtain 4 - trifluoromethyltoluene.
    Then, 4 - trifluoromethyltoluene is nitrified. Using mixed acid (nitric acid and sulfuric acid) as the reactant, the temperature is controlled in a suitable range, so that the nitro group enters the position of the benzene ring o-methyl to obtain 2-Methyl-1-Nitro-4-Trifluoromethyl-Benzene.
    In this process, the catalytic agent, the temperature of the reaction, and the ratio of raw materials are all required. It is appropriate to set up a temperature control device to measure the reaction process, so that the reaction can be smooth and efficient. And when preparing a method of separation and purification, to obtain a pure product. In this way, the desired product can be prepared.
    Chemical Reactions & Modifications
    2 - Methyl - 1 - Nitro - 4 - Trifluoromethyl - Benzene is an important chemical product. In the field of chemical synthesis, its chemical reaction and modification are crucial.
    To prepare this compound, a delicate reaction path is often required. For example, a specific aromatic compound is used as the starting material, and methyl, nitro and trifluoromethyl are gradually introduced through nitrification, halogenation and other reaction steps. Among them, the nitrification reaction needs to pay attention to the control of the reaction conditions. Temperature and reagent ratio will affect the yield and purity of the product.
    Talk about modification, or the method of functional group transformation can be used to make it have different chemical properties. For example, the reduction of nitro groups can obtain corresponding amino compounds, expanding their application in drug synthesis, materials science and other fields. Or adjust the position and type of substituents to observe their impact on molecular activity and physical properties. After many chemical reactions and modifications, the potential value of 2 - Methyl - 1 - Nitro - 4 - Trifluoromethyl - Benzene may be more fully demonstrated.
    Synonyms & Product Names
    Today there is a thing called 2 - Methyl - 1 - Nitro - 4 - Trifluoromethyl - Benzene. Although its name is complex, it is crucial for my chemical research.
    The alias and trade name of this thing also need to be carefully examined. The alias is derived because of its nature, structure or the habit of previous research. The trade name is related to market circulation and is well known to buyers and sellers.
    Find its synonyms, or because of regional differences, or because of different research focuses, and there are different titles. It is subtle, just like the different versions of ancient books, each with its own origin and its own rationale. The name of the product is like the sign of the store, which is eye-catching and unique, used to distinguish similar things.
    For our researchers, by clarifying its synonyms and trade names, we can accurately locate and understand the mysteries of this thing in the vast sea of literature, paving the way for the progress of chemical research.
    Safety & Operational Standards
    2-Methyl-1-Nitro-4-Trifluoromethyl-Benzene, it is also necessary to dispose of things. Its safe operation is essential.
    The first thing to do with the placement of this thing is to be familiar with its nature. Its nature is active, and it is difficult to encounter things, or there may be things like life. Therefore, when handling it, you must follow the rules carefully.
    If you want to operate it safely, you must first ensure that the environment you work in is clean and good. This is why harmful materials are scattered, so as not to gather and be damaged. Furthermore, the operator must use suitable equipment, such as protective clothing, gloves, and masks, to separate and connect them, so as to protect yourself.
    When you exist in the world, it is appropriate to avoid the source of fire. And separate other things, especially avoid the proximity of anti-sexual objects, in order to prevent accidental transformation.
    If there is an accident that affects the skin or the eyes, it is necessary to use a large amount of water to treat it. In case of leakage, the quick separation is prohibited, and those who are prohibited from entering. A small amount of leakage can be adsorbed and cleared by sand and other materials; a large amount of leakage can be handled according to the method of hard work.
    In this case, the safe operation and safety of the 2-Methyl-1-Nitro-4-Trifluoromethyl-Benzene are all related to the safety of the human environment. The operator must not follow it, so as to avoid danger.
    Application Area
    Today there is a thing called 2 - Methyl - 1 - Nitro - 4 - Trifluoromethyl - Benzene, which is widely used. In the field of medicine, it can be used as a special agent to treat various diseases, or to help doctors find a way to overcome difficult diseases. In agriculture, it can be used as a medicine to eliminate pests, protect crops from insect invasion and disease disturbance, and increase the harvest of fields. And in the creation of materials, it also has its function. It can participate in strengthening materials to make them tough, corrosion-resistant, and heat-insulating. It can be used in the construction of large buildings and car buildings, which can increase its quality and prolong its life. Looking at this material, it is essential for medicine, agriculture, and materials, and can help the prosperity of all things and benefit the prosperity of people's lives.
    Research & Development
    Today, there is a product called 2 - Methyl - 1 - Nitro - 4 - Trifluoromethyl - Benzene, which is very important in our chemical research. We have dedicated ourselves to studying its properties and preparation methods, hoping to make progress and promote its development.
    We have carefully investigated its molecular structure and studied its reaction mechanism. We hope to optimize the synthesis method. After months of experiments, we have tried to prepare various paths, or change the reaction conditions, or change the reaction raw materials, in order to achieve better yield and purity.
    Although the process is difficult, every achievement encourages us to move forward. We firmly believe that with time, we will be able to achieve remarkable results in the research and development of 2 - Methyl - 1 - Nitro - 4 - Trifluoromethyl - Benzene, which will contribute to the field of chemistry and benefit everyone.
    Toxicity Research
    The industry of chemical industry is related to people's livelihood, but the study of poisons in it should not be careless. Today there is a thing called 2-Methyl-1-Nitro-4-Trifluoromethyl-Benzene, and the poison of its nature needs to be investigated in detail.
    The poison of this thing, or the living beings. If it enters the body, the viscera may be damaged, and the qi and blood may be chaotic. Looking at various experiments, when the white rat touches it, it is in a depressed state, the diet is gradually wasted, and the body is getting worse. It is also a serious disaster in the ecology. If it flows in the water, the aquatic things are difficult to survive; scattered in the countryside, the grass or withered.
    We should study it with awe. Explore its toxicology, understand its source of harm, and make sure to prevent it with skills and avoid its scourge. Or make good laws to remove its toxicity; or make regulations and use it carefully. In this way, the chemical industry can thrive, and the poison can be eliminated, so as to live up to the responsibility of the researcher.
    Future Prospects
    I try to research chemical products, and I am particularly concerned about the product 2 - Methyl - 1 - Nitro - 4 - Trifluoromethyl - Benzene. Looking at this substance, its unique nature and wide range of uses. In today's world, industrial fields may already have their uses.
    Looking to the future, the development of this product seems to be possible. In fine chemicals, it may be a key raw material to help the research and development of new products. In the field of medicine, it may be modified and transformed into a special drug. On top of agriculture, it may also become a new type of pesticide to protect the health of crops.
    Although the road ahead may be difficult, science and technology are advancing day by day. Our scientific researchers should make unremitting explorations. It is hoped that with wisdom and sweat, we will expand the new territory of this product, seek well-being for future generations, and make it shine in the future, which will help industrial progress and people's livelihood improvement.
    Where to Buy 2-Methyl-1-Nitro-4-Trifluoromethyl-Benzene in China?
    As a trusted 2-Methyl-1-Nitro-4-Trifluoromethyl-Benzene manufacturer, we deliver: Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements. Technical Excellence: Precision-engineered solutions backed by R&D expertise, from formulation to end-to-end delivery. Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.
    Frequently Asked Questions

    As a leading 2-Methyl-1-Nitro-4-Trifluoromethyl-Benzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

    What are the main uses of 2-methyl-1-nitro-4-trifluoromethylbenzene?
    2-% methyl-1-naphthyl-4-trifluoromethylbenzene sulfone, its main uses are as follows.
    This compound is quite useful in the field of organic synthesis. First, it is often an intermediate for the preparation of drugs with specific structures. Due to the design of drug molecules, precise structures are required to fit specific biological targets, and the unique structure of the compound, containing groups such as methyl, naphthyl and trifluoromethyl, can endow the final product drug with unique physicochemical properties and biological activities. For example, in the research and development process of some anti-tumor drugs, by introducing such structural units, the lipophilicity, metabolic stability and binding affinity with the target of the drug can be adjusted, and the drug can more effectively penetrate the cell membrane and reach the inside of the tumor cell, thereby enhancing the anti-tumor curative effect.
    Second, it also has applications in the field of materials science. Because of its strong electronegativity and hydrophobicity, trifluoromethyl can improve the surface properties of the material. For example, when preparing high-performance polymer materials, introducing them into the polymer main chain or side chain as a structural unit can improve the chemical corrosion resistance, thermal stability and surface hydrophobicity of the polymer. For example, in the special polymer coating materials used in the aerospace field, after adding compounds containing this structure, the coating can better resist harsh environmental erosion and prolong the service life of the material.
    Furthermore, it also contributes to the research and development of pesticides. It can be used as a structural module of new pesticide molecules, endowing pesticides with excellent biological activity and environmental adaptability. The presence of trifluoromethyl can enhance the interaction between molecules and the check point of insects or plant pathogens, and improve the insecticidal and bactericidal effects of pesticides. At the same time, the appropriate combination of substituents can help optimize the degradation performance of pesticides in the environment and reduce the negative impact on the environment, which is in line with the development needs of modern green pesticides.
    What are the physical properties of 2-methyl-1-nitro-4-trifluoromethylbenzene?
    2-% methyl-1-naphthyl-4-trifluoromethylnaphthalene, this is a rare organic compound. Its physical properties are unique and have potential uses in many fields.
    Looking at its properties, under room temperature and pressure, it is mostly white to light yellow crystalline powder, which is conducive to its uniform dispersion in specific reaction systems and participation in various chemical reactions.
    When it comes to melting point, it is about [X] ° C. The characteristics of melting point are of great significance for its application in the fields of material synthesis and other fields. If it is used in the preparation of special polymer materials, precise control of its melting point can ensure the stability and uniformity of the material molding process and improve the material quality.
    In terms of boiling point, it is about [X] ° C. The higher boiling point means that it can still maintain a stable state in a relatively high temperature environment and is not easy to volatilize. This property makes it suitable for high temperature reaction systems. For example, some organic synthesis reactions that need to be carried out under specific high temperature conditions can ensure that the compound will not be lost due to volatilization during the reaction process, ensuring the smooth progress of the reaction.
    In terms of solubility, it exhibits good solubility in organic solvents such as dichloromethane, chloroform, N, N-dimethylformamide (DMF), etc., but it is difficult to dissolve in water. In the organic synthesis experiment operation, according to the solubility characteristics, a suitable reaction solvent can be reasonably selected in order to construct a homogeneous reaction system and promote the efficient progress of the reaction. In the field of drug research and development, if it is used as a lead compound for drug design, it is necessary to consider the effect of its solubility on the pharmacokinetic properties such as drug absorption and distribution, and improve its utilization in vivo through reasonable structural modification or preparation means.
    Density is also an important physical property, about [X] g/cm ³. Density data is crucial in the measurement of materials in chemical production, the design of reaction equipment, etc., which can help to accurately calculate the input of reaction materials, ensure that the reaction is carried out in the expected proportion, and avoid the increase of side reactions or substandard product quality due to the imbalance of material ratio.
    Is the chemical properties of 2-methyl-1-nitro-4-trifluoromethylbenzene stable?
    The chemical properties of 2-% methyl-1-naphthyl-4-trifluoromethylbenzene are quite stable. In this compound, methyl and trifluoromethyl are both common substituents in organic chemistry. As a donator group, methyl can affect the electron cloud density of the benzene ring, but its donator effect is relatively weak. Trifluoromethyl has strong electron-absorbing properties, which can significantly reduce the electron cloud density of the benzene ring.
    From the perspective of spatial structure, the naphthyl structure endows the molecule with a larger conjugated system and increases the stability of the molecule. The fused ring structure of naphthyl makes the molecule planar and has a high degree of electron delocalization.
    In chemical reactions, due to the strong electron absorption of trifluoromethyl, the electron cloud density on the benzene ring decreases, making it relatively difficult to occur electrophilic substitution reactions. For example, electrophilic substitution reactions such as halogenation and nitrification may require more harsh reaction conditions than similar compounds without trifluoromethyl.
    On the other hand, carbon-carbon bonds, carbon-hydrogen bonds and other chemical bonds in the molecule are relatively stable due to the difference in electronegativity of each atom and the existence of conjugation effects. Under normal heating and light isothermal conditions, the molecular structure will not be easily changed.
    In addition, the chemical stability of 2-% methyl-1-naphthyl-4-trifluoromethylbenzene is also reflected in its resistance to common chemical reagents. Under extreme conditions such as non-strong acids, strong bases and strong oxidizing agents, the compound can maintain its own structure and chemical properties relatively stable, and will not rapidly decompose or other chemical reactions. In summary, 2-% methyl-1-naphthyl-4-trifluoromethylbenzene has relatively stable chemical properties in common chemical environments.
    What are the preparation methods of 2-methyl-1-nitro-4-trifluoromethylbenzene?
    To prepare 2-methyl-1-propyl-4-trifluoromethylbenzene, there are various methods, which are listed as follows:
    First, start with an aromatic hydrocarbon containing the corresponding substituent, and introduce halogen atoms at a suitable check point in the benzene ring by halogenation reaction. After that, the metal reagent, such as Grignard's reagent or lithium reagent, generates an active intermediate. Then make it with a reagent containing trifluoromethyl, such as trifluoromethyl magnesium halide, etc., through a nucleophilic substitution reaction, add trifluoromethyl. Then, after appropriate steps, construct 1-propyl and 2-methyl. For example, the corresponding alkylation reagent is first prepared from halogenated propane and metal reagents, and 1-propyl is introduced by reacting with benzene ring intermediates, and then 2-methyl is introduced by similar methods or by specific methylation reagents, such as iodomethane and alkali.
    Second, benzene derivatives with partial substituents can be started. For example, benzene containing 2-methyl and halogen is first metallized and then reacted with reagents containing trifluoromethyl and 1-propyl structures. The key here is to design suitable synthons containing trifluoromethyl and 1-propyl, so that both can be connected to the benzene ring simultaneously or step by step. The synthesizer can be prepared in multiple steps, such as starting with propanol, halogenated to obtain halogenated propane, and then connected with a group containing trifluoromethyl to construct the desired structural fragment, and then reacted with the benzene ring intermediate.
    Third, the coupling reaction catalyzed by transition metals. Select halogenated aromatics or aromatic boric acid derivatives containing different substituents. Such as halogenated benzene containing 2-methyl and borate esters or halogenates containing 1-propyl and trifluoromethyl, in the presence of transition metal catalysts and ligands such as palladium and nickel, the target molecule is constructed by coupling reaction. This requires fine regulation of reaction conditions, including catalyst type and dosage, ligand structure, alkali type and reaction temperature, etc., to achieve good reaction selectivity and yield.
    The above methods have their own advantages and disadvantages. When implemented, it needs to be weighed according to factors such as raw material availability, cost, reaction conditions and purity of target products.
    What are the precautions for storing and transporting 2-methyl-1-nitro-4-trifluoromethylbenzene?
    2-% methyl-1-cyano-4-trifluoromethylbenzene requires attention to many matters during storage and transportation. This is a chemical substance with unique properties. If you are not careful, it will cause disaster.
    In terms of storage, the first environment to choose. It should be placed in a cool and ventilated place, away from fire and heat sources. Because of its flammability, high temperatures and open flames are easily dangerous. The warehouse temperature should be controlled within a reasonable range, not too high, to prevent changes in material properties. And keep it dry and avoid humid environments. Due to moisture or chemical reactions, its quality will be damaged, and even safety accidents will result.
    Furthermore, the storage place should be separated from oxidants, acids, bases, etc. These substances are chemically active, contact with 2% methyl-1-cyano-4-trifluoromethylbenzene, or react violently, endangering safety. At the same time, the storage area needs to have good sealing conditions to prevent the substances from evaporating into the air, which will not only damage the substances themselves, but also pollute the environment, and may also cause poisoning.
    When transporting, do not slack off. The transport vehicle must ensure good safety performance, and be equipped with corresponding fire fighting equipment and leakage emergency treatment equipment. The loading process must be careful to prevent damage to the container. If the container breaks and the material leaks, the consequences will be unimaginable. During transportation, drive at a steady speed and avoid violent actions such as sudden braking and sharp turns to prevent the container from being damaged by collision.
    The escort must have professional knowledge and be familiar with the characteristics of the substance and emergency treatment methods. Once there is an abnormality such as leakage on the way, effective measures can be taken quickly to reduce the harm. In addition, the transportation route should avoid densely populated areas and environmentally sensitive areas to prevent leakage from causing serious impact on the public and ecology.
    In short, the storage and transportation of 2-% methyl-1-cyano-4-trifluoromethylbenzene requires all-round attention. Any negligence in details may lead to serious consequences, endangering life, property and environmental safety.