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2-Iodo-5-Fluoronitrobenzene

2-Iodo-5-Fluoronitrobenzene

Hongda Chemical

    Specifications

    HS Code

    242581

    Chemical Formula C6H3FINO2
    Molar Mass 267.00 g/mol
    Appearance Solid (usually a yellow - colored solid)
    Melting Point Data depends on purity, typically in a certain range, e.g., around 90 - 95°C
    Solubility In Water Insoluble in water
    Solubility In Organic Solvents Soluble in common organic solvents like dichloromethane, chloroform
    Density Specific density value depends on conditions, relatively high density due to heavy atoms
    Stability Stable under normal conditions, but sensitive to light and heat
    Hazard Class Irritant, may cause harm to skin, eyes and respiratory system

    As an accredited 2-Iodo-5-Fluoronitrobenzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing 100g of 2 - iodo - 5 - fluoronitrobenzene packaged in a sealed, labeled container.
    Storage 2 - iodo - 5 - fluoronitrobenzene should be stored in a cool, dry, well - ventilated area. Keep it away from heat sources, flames, and oxidizing agents. Store in a tightly - sealed container to prevent exposure to air and moisture, which could potentially cause degradation. It should be separated from incompatible substances in a dedicated storage space for hazardous chemicals.
    Shipping 2 - iodo - 5 - fluoronitrobenzene, a chemical, is shipped in specialized, leak - proof containers. These are carefully packed to prevent breakage. Shipments follow strict hazardous material regulations to ensure safe transportation.
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    2-Iodo-5-Fluoronitrobenzene 2-Iodo-5-Fluoronitrobenzene
    General Information
    Historical Development
    The industry of chemical industry is changing with each passing day, and new products are emerging one after another. Today there is 2-Iodo-5-Fluoronitrobenzene. Its origin is also the work of scholars.
    At the beginning, everyone explored in the field of chemistry, seeking new qualities to meet the needs of everything. After months of poverty and repeated experiments, this compound was obtained. Its structure is exquisite, its properties are unique, and it is gradually useful in organic synthesis and other aspects.
    At that time, various scholars used it as a basis to expand their research. Or explore its reaction mechanism, or study its derivation method. With the passage of time, the technology has advanced, the preparation method has improved, and the yield has gradually increased. Its contribution to the pharmaceutical, materials and other industries has been growing, and it has become an indispensable material in today's chemical industry. This is the outline of its development.
    Product Overview
    2-Iodine-5-fluoronitrobenzene, an organic compound. Its shape or crystalline, the color is light yellow. This compound has unique chemical properties, iodine, fluorine and nitro coexist on a benzene ring. Iodine has strong nucleophilic substitution activity, and can interact with many nucleophilic reagents under suitable conditions to derive other compounds. The introduction of fluorine atoms, due to the high electronegativity of fluorine, significantly affects the electron cloud distribution of molecules, thereby changing the physical and chemical properties of compounds. The presence of nitro groups makes the substance more reactive, and it is often used as a key intermediate in the field of organic synthesis.
    can be prepared through a specific reaction path during synthesis. For example, the corresponding halogenated benzene is used as the starting material, and the structure of this compound is precisely constructed through a series of reactions such as halogenation and nitrification. It has potential application value in many fields such as medicine and materials. In pharmaceutical research and development, it may be used as a lead compound to help create new drugs; in the field of materials science, it can also be an important cornerstone for the preparation of materials with special properties.
    Physical & Chemical Properties
    2 - Iodo - 5 - Fluoronitrobenzene is also an organic compound. Its physical and chemical properties are related to many aspects. Looking at its properties, under normal temperature, or as a solid state, it has a specific color and state. The melting point is the temperature at which a substance changes from a solid state to a liquid state. The melting point of this compound has its specific value, which is related to the intermolecular force and lattice structure. The boiling point also has a fixed number, which is the temperature limit for liquids to gaseous states.
    In terms of solubility, it varies in different solvents. In polar solvents, such as alcohols, or due to similar miscibility principles, it has a certain solubility; in non-polar solvents, such as alkanes, the solubility may be low. Its chemical properties are active, and iodine atoms, fluorine atoms and nitro groups are all reactive. Nitro groups can be reduced, and fluorine and iodine atoms can participate in substitution reactions. They are widely used in the field of organic synthesis and are important raw materials for the preparation of many fine chemicals.
    Technical Specifications & Labeling
    There is 2 - Iodo - 5 - Fluoronitrobenzene today, which is related to its technical specifications and identification (product parameters), when detailed. Its shape and color, when it is [specific color, not provided here], and the smell needs to be identified. As for purity, above [X]%, the impurity content must be controlled at a very low level. Its melting point, melting at [specific melting point], boiling at [specific boiling point].
    In terms of marking, the name "2 - Iodo - 5 - Fluoronitrobenzene" must be written on the packaging, and it must be marked with a hazard warning, if it belongs to [specific hazard category, such as toxic, flammable, etc.], to prevent accidental touch and misuse. Its technical specifications are detailed, which is a proof of quality. The logo is clear, and the use is guaranteed to be correct. In the research and application of chemical industry, both of these are important.
    Preparation Method
    The method of preparing 2-iodine-5-fluoronitrobenzene is related to the raw materials, production process, reaction steps and catalytic mechanism. First, fluorobenzene is taken as the starting material, and nitrate-sulfur mixed acid nitrate is used. The temperature control is about 50 to 60 degrees to obtain 5-fluoronitrobenzene. This step is electrophilic substitution, the nitro group enters the benzene ring, and the o-para-position is activated by the fluoro group. 5-fluoronitrobenzene is the main product.
    The copper salt activates iodine and promotes its nucleophilic substitution with 5-fluoronitrobenzene to generate 2-iodine-5-fluoronitrobenzene. The reaction needs to be protected by inert gas, in an organic solvent, the temperature is controlled at about 80 to 90 degrees, and the yield and purity can be improved.
    The whole process is to fine screen the raw materials, strictly control the reaction conditions, and ensure that the equipment is in good condition to ensure the smooth process, and obtain the best 2-iodine-5-fluoronitrobenzene products.
    Chemical Reactions & Modifications
    Recently researched 2 - Iodo - 5 - Fluoronitrobenzene, I have experience in the transformation of this product. The beauty of the reverse, such as the intersection, the transformation of thousands. The same as in the past, or gain or lose, are all today's.
    At the beginning of the study, according to the method, the reaction is slow and the rate is not high. Thinking about it, the reason is because the product is not yet in agreement, such as the degree of dissolution. Then the whole strategy is completed, and the result is improved with the new degree and dissolution. This transformation is like a boat going against the current, and it is easy to move forward.
    As for the performance, 2 - Iodo - 5 - Fluoronitrobenzene is contained in the water, and it is different in different environments. Its iodine, fluorine, and nitro groups interact with each other, giving this material its characteristics. We will study it and make good use of it, so as to be the cornerstone of synthesis, hoping to be new and promote the next step of transformation, for the benefit of the world.
    Synonyms & Product Names
    2-Iodine-5-fluoronitrobenzene is also a good product. Its different names and trade names are also the subject of our investigation. The different names are the same thing and different names, which help us to know the various names of this thing in detail. Trade names are related to market trade and circulation, and are valued by merchants.
    2-iodine-5-fluoronitrobenzene, in the chemical environment, has its own specificity. Its different names or stand according to its structure and characteristics to show its characteristics. Trade names are related to the market and are often given unique names to attract customers' attention.
    To understand its synonyms and trade names, we need to study the literature, explore the canon of chemical industry, and study the theory of the industry. After this study, we can get the whole picture, which is beneficial to scientific research and business. We can use it accurately and travel smoothly in the chemical industry.
    Safety & Operational Standards
    2-Iodo-5-Fluoronitrobenzene Safety and Operating Practices
    2-Iodo-5-Fluoronitrobenzene is an important chemical that is widely used in scientific research and related industries. However, it is dangerous, so when operating, it must strictly follow safety and operating specifications to ensure the safety of personnel and the smooth operation of experiments and production.
    #Storage Safety
    This substance should be stored in a cool, dry and well-ventilated place. Keep away from fire and heat sources and prevent direct sunlight. Because of its certain chemical activity, it must be stored separately from oxidants, reducing agents, acids, alkalis, etc., and should not be mixed. The storage area should be equipped with suitable materials to contain leaks to prevent accidental leakage from causing harm.
    #Operating Specifications
    Operators must be specially trained and strictly abide by operating procedures. When operating, appropriate protective equipment should be worn, such as protective glasses, acid and alkali gloves, protective clothing, etc., to avoid skin contact and eye splashing.
    Operate in a fume hood to ensure good ventilation conditions and prevent the accumulation of harmful gases. When taking 2-Iodo-5-Fluoronitrobenzene, be careful to avoid spillage. If it is accidentally spilled, emergency measures should be taken immediately. In the event of a small leak, mix sand, dry lime or soda ash and collect in a dry, clean, covered container. If there is a large amount of leakage, build a dike or dig a pit to contain it, transfer it to a tanker or a special collector with a pump, and recycle or transport it to a waste disposal site for disposal.
    #Emergency Treatment
    If the skin comes into contact with 2-Iodo-5-Fluoronitrobenzene, immediately remove the contaminated clothing, rinse with a large amount of flowing water for at least 15 minutes, and seek medical attention. If eye contact, immediately lift the eyelids, rinse thoroughly with a large amount of flowing water or normal saline for at least 15 minutes, and seek medical attention. If inhaled, quickly leave the scene to a fresh air place to keep the respiratory tract unobstructed, such as breathing difficulties, give oxygen, if breathing stops, immediately perform artificial respiration and seek medical attention.
    In short, when dealing with 2-Iodo-5-Fluoronitrobenzene, whether it is storage, operation or emergency treatment, it should not be taken lightly, and it is necessary to strictly follow the safety and operation specifications to ensure safety.
    Application Area
    2 - Iodo - 5 - Fluoronitrobenzene is an important chemical substance. Its application field is quite wide. In the field of pharmaceutical synthesis, it can be used as a key intermediate to help create a variety of specific drugs, or used to develop innovative therapies for specific diseases to solve the suffering of patients. In the field of materials science, it also has its place. It can be integrated into the construction of new materials through specific reactions, giving materials such as unique optical and electrical properties to meet the special needs of materials in different scenarios. It can also show its skills in the field of fine chemicals, contribute to the preparation of high-end fine chemicals, improve the quality and performance of products, and thus play an indispensable role in industrial production and scientific research and exploration.
    Research & Development
    In recent years, I 2-Iodo-5-Fluoronitrobenzene this compound and devoted myself to it. This compound has a unique structure and different properties, and has great potential in the field of organic synthesis.
    At the beginning, I explored the preparation method, tried many times, and experienced ups and downs. The ratio of raw materials and reaction conditions are all carefully investigated. Or the change of temperature, or the choice of catalyst, a slight difference in the pool, the results are very different. Fortunately, thanks to persistence, I gradually obtained exquisite methods, and the yield also steadily increased.
    Then study its properties, chemical activity, stability, etc., all of which are deeply analyzed. Knowing that it can be a key intermediate in a specific reaction, it can expand many synthesis paths.
    Looking to the future, we hope to open up new fields based on this product. In pharmaceutical research and development, it may become a unique drug; in material creation, it may produce novel materials. Unremitting research, hoping that it will shine, adding a new chapter to the academic world and promoting the progress and prosperity of this field.
    Toxicity Research
    Modern chemistry has flourished, and the study of poisons is very important. Today there is a thing, the name 2-Iodo-5-Fluoronitrobenzene, and the study of its toxicity cannot be ignored.
    This thing is also unique in structure, iodine, fluorine and nitro are combined in the benzene ring. The nature of iodine is very active, and fluorine also has its specificity. Nitro is in the inside, or causes toxic changes.
    After various experiments, its effect on organisms is observed. When it is introduced into microinsects, it can be seen that its action is sluggish and physiological violations. When applied to grass and trees, the color of the leaves may change, and the vitality will be blocked.
    From this perspective, the toxicity of 2-Iodo-5-Fluoronitrobenzene is significant. When it is used in industrial production and use, it must be carefully protected against leakage, so as not to cause harm to life and the environment. The deeper the research, the more we can know its nature, avoid its harm, and use its benefits to promote the progress of chemistry and maintain the harmony of all things.
    Future Prospects
    2-Iodine-5-fluoronitrobenzene, viewed today, is a fine chemical product, but I see it as the foundation for the future. This substance has unique chemical properties and has infinite potential in the field of organic synthesis.
    In today's world, science and technology are changing, and various industries are increasingly seeking fine chemicals. 2-Iodine-5-fluoronitrobenzene, with its special structure, can be used as a key raw material for the synthesis of many types of high-end materials and special drugs. In the future, the development of medicine may seek more accurate and efficient targeted drugs, and this substance may become an indispensable cornerstone to help doctors overcome intractable diseases and save thousands of lives from pain.
    In the field of materials, with the progress of electronics, aerospace and other industries, the demand for special materials has surged. 2-Iodine-5-fluoronitrobenzene may be an important corner for the creation of new photoelectric materials and high-strength composites, promoting science and technology to make great strides forward, opening up unprecedented territory, and making the future bright and promising, with endless development in front of our eyes.
    Where to Buy 2-Iodo-5-Fluoronitrobenzene in China?
    As a trusted 2-Iodo-5-Fluoronitrobenzene manufacturer, we deliver: Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements. Technical Excellence: Precision-engineered solutions backed by R&D expertise, from formulation to end-to-end delivery. Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.
    Frequently Asked Questions

    As a leading 2-Iodo-5-Fluoronitrobenzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

    What are the main uses of 2-Iodo-5-Fluoronitrobenzene?
    2-Iodine-5-fluoronitrobenzene is one of the most important compounds in organic synthesis. It has a wide range of uses and has extraordinary applications in medicine, pesticides, material science and other fields.
    In the field of medicinal chemistry, this compound is often a key intermediate for the synthesis of new drugs. Due to the special combination of iodine, fluorine and nitro in its structure, it is endowed with unique chemical and biological activities. Chemists can chemically modify it in a variety of ways and introduce different functional groups to construct molecular structures with specific pharmacological activities. For example, for a specific disease target, design and synthesize drug molecules that fit it to achieve the purpose of treating diseases.
    In the field of pesticides, 2-iodine-5-fluoronitrobenzene also plays an important role. It can be chemically converted to synthesize pesticides with high insecticidal, bactericidal or herbicidal properties. Its special structure can enhance the interaction between pesticides and specific receptors or enzymes in target organisms, enhance the biological activity and selectivity of pesticides, reduce the impact on non-target organisms, and achieve efficient and environmentally friendly pesticide creation.
    In the field of materials science, this compound can be used to prepare functional materials. For example, by participating in polymerization reactions or other chemical synthesis processes, special functional groups can be introduced into the material structure, endowing the material with unique properties such as photoelectric properties, thermal stability, solubility, etc., providing the possibility for the development of new functional materials, and showing potential application value in electronic devices, optical materials, etc.
    In summary, 2-iodine-5-fluoronitrobenzene, with its unique chemical structure, has opened the door to innovative research for scientists in many fields, promoting the development and progress of technologies in various fields.
    What are the physical properties of 2-Iodo-5-Fluoronitrobenzene?
    2-Iodine-5-fluoronitrobenzene is also an organic compound. Its physical properties are worth studying in detail.
    Looking at its properties, at room temperature, it is mostly white to light yellow crystalline powder. This form is easy to store and use, and also affects its dispersion and reaction characteristics in different environments.
    When it comes to the melting point, it is about [specific melting point value]. The level of the melting point is related to the conditions of its phase transition, and it has a huge impact on its behavior in various thermal processing processes. If the temperature reaches this value, the substance will gradually melt from the solid state to the liquid state, and the change of the intermolecular force is fully apparent.
    Its solubility is also an important physical property. In organic solvents such as dichloromethane, N, N-dimethylformamide, it has good solubility. This property makes it participate in many organic synthesis reactions in solution form, and the solvent can help its molecules disperse uniformly, improving the reaction efficiency and selectivity. However, in water, its solubility is very small, because the molecular structure of the compound is dominated by hydrophobic groups, and it is difficult to form effective interactions with water molecules.
    In addition, the density of the substance is also a key physical parameter. The size of the density reflects the mass of the substance per unit volume, which is of great significance for its phase distribution and separation operations in the mixed system.
    As for its vapor pressure, it is relatively low at room temperature. This shows that the substance has a weak tendency to evaporate from liquid to gaseous at room temperature and pressure, which helps it maintain a stable state under normal storage conditions and reduce losses and potential safety risks caused by volatilization.
    The physical properties of 2-iodine-5-fluoronitrobenzene are of great significance in many fields such as organic synthesis and drug development, providing a solid foundation for related research and production practices.
    What are 2-Iodo-5-Fluoronitrobenzene synthesis methods?
    The synthesis method of 2-iodine-5-fluoronitrobenzene has been explored by many parties throughout the ages, and each method has been applied to achieve the purpose of preparation. The common method is the nucleophilic substitution reaction. In this method, the appropriate halogenated aromatic hydrocarbon is selected as the substrate, and its structure must be suitable for the target product. Then find the nucleophilic reagent, the activity of this reagent needs to be moderate, in order to react smoothly. Under appropriate reaction conditions, such as suitable temperature, pressure and solvent environment, the nucleophilic reagent attacks the halogen atom of the halogenated aromatic hydrocarbon, and then becomes the target product. However, in this process, the activity of the halogen atom, the basicity and steric resistance of the nucleophilic reagent are all key factors affecting the reaction process and yield.
    Another metal-catalyzed coupling reaction is also a common strategy. Specific metal catalysts, such as palladium and copper, are selected to play a key catalytic role in the reaction. With suitable ligands to enhance the activity and selectivity of metal catalysts. Using aromatic hydrocarbon derivatives containing iodine, fluorine and nitro groups as raw materials, under the synergistic action of metal catalysts and ligands, the coupling reaction occurs with other suitable coupling reagents to construct the target molecular structure. During the reaction, the loading amount of the catalyst, the structure of the ligand, and the ratio of the reaction substrate need to be finely regulated to enable the reaction to proceed efficiently and obtain the ideal yield and purity.
    In addition, it can also be synthesized through a multi-step reaction strategy. First, the basic aromatic hydrocarbon compound is used as the starting material, and the nitro group is introduced through the nitrification reaction, and then the halogenation reaction is carried out to introduce iodine and fluorine atoms. This multi-step reaction requires precise control of the reaction conditions of each step to ensure the yield and selectivity of each step, and the separation and purification of intermediate products are also crucial. A little carelessness will affect the quality and yield of the final product.
    All the above synthesis methods have their own advantages and disadvantages, and need to be carefully selected according to actual needs, raw material availability, cost considerations and many other factors in order to achieve the best synthesis effect.
    What 2-Iodo-5-Fluoronitrobenzene need to pay attention to when storing and transporting
    2-Iodine-5-fluoronitrobenzene is a chemical commonly used in organic synthesis. When storing and transporting, care must be taken. The following points must be paid attention to.
    First words storage. This substance is quite sensitive to light, and light can easily cause it to react chemically. Therefore, it should be stored in a container that is shaded from light, and the warehouse should also be kept dark. In addition, its chemical properties are active, easily decomposed when heated, and even dangerous. Therefore, it should be placed in a cool place, and the temperature should not exceed 25 ° C. At the same time, this substance is toxic and corrosive to a certain extent. In order to prevent leakage from causing harm, the storage environment must be dry, the humidity should be controlled below 60%, and it should be stored separately from oxidants, acids, alkalis, etc., and must not be mixed in storage to prevent mutual reaction. In addition, the storage area should be equipped with the corresponding variety and quantity of fire equipment and leakage emergency treatment equipment for emergencies.
    times and transportation. Before transportation, it is necessary to ensure that the packaging is complete and sealed to prevent leakage. During transportation, it is necessary to ensure that the container does not leak, collapse, fall, or damage. This substance is a hazardous chemical, and the relevant dangerous chemical transportation regulations must be strictly followed during transportation. It should be carried by transportation enterprises and personnel with corresponding qualifications. Transportation vehicles should be equipped with corresponding fire equipment and leakage emergency treatment equipment, and the driving route should try to avoid sensitive areas such as densely populated areas and water source protection areas. And during transportation, it is necessary to pay close attention to the status of the goods, regularly check whether the packaging is in good condition, and if there is any abnormality, it should be properly handled immediately.
    What is the market outlook for 2-Iodo-5-Fluoronitrobenzene?
    2-Iodine-5-fluoronitrobenzene is a key intermediate in the field of organic synthesis. Looking at its market prospects, it is quite promising.
    From the perspective of medicinal chemistry, this compound often plays a key role in the creation of new drugs. In the molecular structure of many drugs, specific substituents need to be introduced to fine-tune their activity and selectivity. The iodine, fluorine and nitro groups contained in 2-iodine-5-fluoronitrobenzene can be combined with other functional groups through ingenious chemical reactions to construct molecules with unique pharmacological activities. Therefore, in the process of anti-tumor, anti-viral and other drug research and development, its traces can often be found, paving the way for the birth of new specific drugs.
    In the field of materials science, with the rapid progress of science and technology, the demand for special performance materials is also increasing day by day. 2-Iodine-5-fluoronitrobenzene can be used as an important starting material for the synthesis of optoelectronic materials, liquid crystal materials, etc. Its unique electronic structure and spatial configuration endow the materials derived from it with different optical and electrical properties. For example, in the synthesis of organic Light Emitting Diode (OLED) materials, molecules based on this compound may optimize the luminous efficiency and stability of the material, contributing to the innovation of display technology.
    In the field of pesticide chemistry, 2-iodine-5-fluoronitrobenzene is also indispensable for the creation of new pesticides with high efficiency, low toxicity and environmental friendliness. By structural modification and derivatization reactions, specific pesticides for specific pests and diseases can be developed, which can not only effectively prevent and control agricultural disasters, but also reduce the adverse impact on the environment, which is in line with the current trend of green agriculture development. Therefore, 2-iodine-5-fluoronitrobenzene has shown broad application prospects in many fields. With the continuous progress of technology in various industries, its market demand is expected to rise steadily, and it will play an increasingly important role in promoting the development of related industries.