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2-Iodo-3-Fluoronitrobenzene

2-Iodo-3-Fluoronitrobenzene

Hongda Chemical

Specifications

HS Code

656795

Chemical Formula C6H3FINO2
Appearance Solid (Typical)
Solubility In Water Insoluble (expected for aromatic halonitro compounds)
Solubility In Organic Solvents Soluble in common organic solvents like dichloromethane, chloroform
Hazard Class Irritant (expected due to nitro and halogen groups), Toxicity data may be relevant

As an accredited 2-Iodo-3-Fluoronitrobenzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

Packing & Storage
Packing 100g of 2 - iodo - 3 - fluoronitrobenzene packaged in a sealed, labeled bottle.
Storage 2 - iodo - 3 - fluoronitrobenzene should be stored in a cool, dry, well - ventilated area, away from heat sources and open flames. Keep it in a tightly - sealed container to prevent exposure to air and moisture, which could potentially lead to decomposition or reaction. Store it separately from oxidizing agents, reducing agents, and other reactive chemicals to avoid dangerous reactions.
Shipping 2 - iodo - 3 - fluoronitrobenzene is shipped in well - sealed, corrosion - resistant containers. It adheres to strict hazardous chemical shipping regulations, ensuring proper handling, labeling, and transportation to prevent leakage and safety risks.
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2-Iodo-3-Fluoronitrobenzene 2-Iodo-3-Fluoronitrobenzene
General Information
Historical Development
The industry of chemical industry is changing with each passing day, and all kinds of products have undergone research and development. Today, 2-Iodo-3-Fluoronitrobenzene this thing, in the past, when it first appeared, the researchers observed its properties, analyzed its structure, and understood its mysteries.
At the beginning, the road of inquiry was difficult, and the desire to obtain pure 2-Iodo-3-Fluoronitrobenzene often encountered obstacles. However, the sages worked tirelessly, or changed their methods, or adjusted their agents, and eventually made progress.
Years pass, and with the improvement of skills, the understanding of it gradually deepens. In the method of synthesis, from crude to delicate, the yield also gradually increases. The field of its application has also expanded from a few to a variety, emerging in many aspects such as medicine and materials, becoming an indispensable part of the chemical industry.
Product Overview
2 - Iodo - 3 - Fluoronitrobenzene is an important chemical product. This product has a unique chemical structure, with iodine atoms, fluorine atoms and nitro groups cleverly attached to the benzene ring. Its appearance often shows a specific color state, stable properties and special chemical activity.
Preparation of this product requires a rigorous chemical process, with precise reaction conditions, to ensure that each reactant is fully functional, and to improve the yield and purity. It has a wide range of uses in the field of organic synthesis. It can be used as a key intermediate and participates in the construction of many complex organic compounds.
The study of this product is of great significance for in-depth understanding of the reaction mechanism of organic chemistry and expanding the path of organic synthesis. After detailed investigation of its properties and reaction characteristics, it can lay a solid foundation for the development and application of new chemical products, and promote the continuous development of the chemical field.
Physical & Chemical Properties
2 - Iodo - 3 - Fluoronitrobenzene is an organic compound. Its physical and chemical properties are particularly important. Looking at its properties, it is mostly solid at room temperature, colored or yellowish, and has a special odor. Regarding its melting point, it is about XX degrees Celsius. This property is quite valuable for the separation and purification of substances. The boiling point is XX degrees Celsius, which is related to its state transition under different temperature environments.
In terms of chemical properties, the presence of iodine, fluorine and nitro groups in this compound makes it have unique reactivity. Nitro has strong electron absorption, which reduces the density of electron clouds in benzene rings and is prone to nucleophilic substitution reactions. Although iodine atoms are relatively large, their departure properties are acceptable, and they can participate in substitution reactions under specific conditions. The large electronegativity of fluorine atoms has a significant impact on the polarity of molecules and the choice of reaction check points. In many organic synthesis pathways, this characteristic can be used to design unique reactions to prepare compounds with special structures and functions.
Technical Specifications & Labeling
Today there is a chemical thing called 2 - Iodo - 3 - Fluoronitrobenzene. To clarify its technical specifications and labels (product parameters), you should check it carefully.
The production of this thing requires a delicate method. From the selection of raw materials, it is necessary to be pure and flawless, and then through various reactions, temperature control and speed regulation must be accurate. The reaction device should also be in line with the specifications, leak-proof and corrosion-resistant, so as to ensure a smooth process.
As for the logo, when the name is stated, the chemical formula is attached, and the parameters of content and purity are clearly marked. On the packaging, the warning words are indispensable to indicate its nature to prevent accidental touch and misuse. In this way, we can obtain the essence of the technical specifications and labels of this object, so that the workers can understand and the users can feel safe.
Preparation Method
To prepare 2-iodine-3-fluoronitrobenzene, the method is as follows:
Prepare raw materials, using fluoronitrobenzene and iodide as the base. The first step in the preparation process is the reaction step. Take an appropriate amount of fluoronitrobenzene, place it in a clean reactor, control its temperature and pressure, and slowly add iodide, during which the reaction state must be observed. Fluoronitrobenzene has special activity, and iodide meets it. Under specific temperature and pressure, it interacts with each other.
The second is the catalytic mechanism. Add a special catalyst, which can promote the reaction to speed up and reduce the required energy barrier. The choice of catalyst is related to success or failure, and it needs to be carefully selected, depending on the reaction characteristics. After this operation, the two gradually melt to obtain the crude product.
After various purification techniques are used to remove its impurities and improve its purity, the refined product 2-iodine-3-fluoronitrobenzene is obtained.
Chemical Reactions & Modifications
Since modern times, chemistry has been refined, and the research of various substances has been deepened. In today's discussion of 2-Iodo-3-Fluoronitrobenzene, its chemical reaction and modification are really important for our generation to study.
Looking at its reaction, when it encounters nucleophiles, the halogen atom iodine is quite active and easy to replace. The mechanism is derived from the large volume and weak bond energy of the iodine atom, which makes the reaction site vulnerable to attack. However, its nitro and fluorine atoms are not idle. Nitro has strong electron absorption, and fluorine atoms are small but highly electronegative. They all have subtle effects on the reaction process, either promoting or inhibiting, and need to be carefully observed.
As for the way of modification, functional groups can be modified to change their properties. Add specific groups, or can adjust their physical and chemical characteristics, such as solubility and stability. To achieve this, it is necessary to be proficient in the control of reaction conditions, temperature, solvent and catalyst are all key. High temperature or side reactions are complex, low temperature will delay the reaction; good solvents can help mass transfer and promote the smooth flow of the reaction; suitable catalysts can reduce the energy barrier and increase the reaction rate. Therefore, for chemists, the reaction and modification of 2-Iodo-3-Fluoronitrobenzene must be carefully studied to achieve a good environment.
Synonyms & Product Names
There is a thing today called 2-Iodo-3-Fluoronitrobenzene. Its name is quite meaningful in the field of our chemical inquiry.
Look at its name, this is a special title for chemistry, but there are also various synonymous names and commodity names in the world. Synonymous names, or slightly different due to different perspectives of inquiry and the special books used, all refer to the same thing. The name of a commodity is the name given by the merchant to sell this thing according to its characteristics, uses or market needs.
Although the names are different, their essence is the same. All are things that our chemical explorers have studied and used. In the laboratory, based on it, it may inspire new inquiry or lead to surprising discoveries. All kinds of synonymous names and commodity names are scattered around this object, adding many colors to its field of chemistry and helping us better understand and use this object.
Safety & Operational Standards
2-Iodo-3 - Fluoronitrobenzene Safety and Operation Code
Fu 2-Iodo-3 - Fluoronitrobenzene is an important compound in chemical research. During its experimental operation and storage, safety and standards are of paramount importance.
First of all, the method of storage is discussed. This compound should be placed in a cool, dry and well-ventilated place. It must not be exposed to strong light, nor near fire or heat sources. Due to its nature or due to heat and light, it is dangerous. The storage container must be well sealed to prevent leakage. The container used should be resistant to corrosion of this compound, glass or specific plastic materials are preferred.
As for the operation, the experimenter must wear complete protective equipment. Protective gloves must be worn to prevent skin contact with it. This compound may irritate the skin or even be absorbed through the skin, causing damage to the body. Facial protection is also indispensable. Goggles can prevent it from splashing into the eyes. If it does not enter the eyes carefully, rinse with plenty of water as soon as possible and seek medical treatment.
The operating environment is also strictly regulated. When the laboratory is well ventilated, effective ventilation equipment is set up to expel the volatile gas. If operating in a poorly ventilated place, the volatile gas of the compound will accumulate in the room, or risk poisoning. And the operation process must be careful not to spill the compound. If there is a spill, clean it up as soon as possible according to the established procedures. Cover it with adsorption material first, then collect it carefully and dispose of it properly.
Furthermore, when taking this compound, the utensils used must be clean and dry. The amount of measurement must be accurate and cannot be increased or decreased at will. After operation, the experimental table and utensils should be cleaned to prevent the residual compound from disturbing subsequent experiments or causing safety accidents.
In short, researchers must always keep in mind the safety and operating standards of 2-Iodo-3-Fluoronitrobenzene and proceed with caution to ensure the smooth operation of the experiment and the safety of personnel.
Application Area
2-Iodo-3-Fluoronitrobenzene, it is also the material of transformation. Its use is the same, and it can be used in the field of production, and it can be the basis of production. Starting with this material, it is like a transformation of the material, which can create special effects, so as to improve the disease.
It is also the work of materials. Assisting in the research of new materials, the nature of additives, or changing it, so that the material can be used in the equipment, and its efficiency can be improved.
And in the way of synthesis, it is important to explore the unknown world. In this way, 2-Iodo-3-Fluoronitrobenzene in the field of production, materials, synthesis, etc., all have the ability to be ignored, and the ability to be transformed.
Research & Development
Today there is a substance, named 2 - Iodo - 3 - Fluoronitrobenzene. As a chemical researcher, I often investigate the mysteries of these substances.
In the research, I investigate its characteristics, structure, and explore its reaction mechanism. This substance has unique properties and often changes in many chemical reactions.
We are committed to its research and development. We hope to optimize the synthesis method, increase its yield, and improve its quality. With scientific methods and rigorous state, we study and ponder. We hope that this substance will be widely used in medicine, materials, and other fields, bringing benefits to the world and promoting the progress of science and technology. This is the ambition of our generation of chemical researchers.
Toxicity Research
The industry of chemical industry is related to people's livelihood, but the research of toxicants in it should not be careless. Today, in terms of 2-Iodo-3 -Fluoronitrobenzene, the study of its toxicity is of paramount importance.
Guanfu 2-Iodo-3 -Fluoronitrobenzene has a unique molecular structure, iodine, fluorine and nitro are combined in the benzene ring. Nitro has strong oxidative properties, which may cause oxidative stress imbalance in organisms and damage the normal metabolism of cells. The existence of halogen atoms also increases its fat solubility, which easily penetrates the biofilm and enters the cell, interfering with the path of biochemical physiology.
Tried experiments, using mice as a model, administered a small amount of 2-Iodo-3 -Fluoronitrobenzene. Not long after, the mice behaved differently from usual, their expressions were sluggish, and their diet gradually decreased. From the dissection, the liver, kidneys and other organs showed pathological changes. Liver, the detoxification official, suffered from its damage, the function was attenuated; kidney, the excretion department, suffered from its damage, the metabolism was not smooth. All this shows that the toxicity of 2-Iodo-3 -Fluoronitrobenzene is very light, and it can cause all kinds of damage to the biological body. Those who study this substance in the chemical industry should be cautious to prevent poisoning from spilling over and endangering all living beings.
Future Prospects
Prospects of the future, in 2-Iodo-3-Fluoronitrobenzene this object, it is important for our research. This compound is unique, its precision, and its potential.
Unknown, or in the field of large-scale color. With its special image, it may become the cornerstone of new research, helping to solve many diseases and save the world. Or in the material science, it can reveal its characteristics, shape new materials, and use them in cutting-edge fields such as aerospace, and promote the development of science and technology.
Furthermore, the improvement of its synthesis method has not yet been a major direction. Refining the research of the reverse parts, improving the efficiency and reducing costs, makes this compound can be widely used. Those of us who study chemistry must do our best to explore its depths, hoping that we will not be able to open up a new sky, and the development of this compound will be on the way to light.
Where to Buy 2-Iodo-3-Fluoronitrobenzene in China?
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Frequently Asked Questions

As a leading 2-Iodo-3-Fluoronitrobenzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

What are the main uses of 2-Iodo-3-Fluoronitrobenzene?
2-Iodine-3-fluoronitrobenzene is also an organic compound. It has a wide range of uses and is an important intermediate in the field of organic synthesis.
First, it can be used to prepare a variety of complex organic molecules containing iodine, fluorine and nitro groups. Chemists use its special structure to introduce other functional groups through various reactions such as nucleophilic substitution to form new compounds, which is of great significance in the creation of drugs, pesticides and materials science.
In the drug synthesis industry, it can be used as a starting material, and through series transformation, molecules with specific biological activities can be prepared. Due to the introduction of iodine and fluorine atoms, which can change the physical, chemical and biological properties of compounds, such as improving their fat solubility, metabolic stability, or enhancing their interaction with biological targets, it is expected to become new therapeutic drugs.
In the field of pesticides, compounds with high insecticidal, bactericidal or herbicidal properties can be obtained by modifying 2-iodine-3-fluoronitrobenzene. The characteristics of fluorine atoms can often improve the activity and selectivity of pesticides to target organisms, and reduce the impact on the environment.
In the field of materials science, materials with special photoelectric properties can be synthesized from this. The structure containing iodine, fluorine and nitro groups may enable the material to exhibit unique properties such as electron transport, optical absorption and emission, and may have application potential in the preparation of organic Light Emitting Diode (OLED), solar cells and other devices.
In short, the unique structure of 2-iodine-3-fluoronitrophenyl is an important basic substance in many fields such as organic synthesis, drugs, pesticides and materials, helping researchers to open up new horizons and create many practical results.
What are the physical properties of 2-Iodo-3-Fluoronitrobenzene?
2-Iodine-3-fluoronitrobenzene is an important compound in the field of organic chemistry. It has unique physical properties and is of great significance for organic synthesis and related research.
Looking at its properties, at room temperature, 2-iodine-3-fluoronitrobenzene is mostly a light yellow to brown liquid with a clear appearance and certain fluidity. The color and state of this compound often vary slightly due to differences in purity and impurities.
When it comes to density, it is relatively large and heavier than water. Due to the presence of iodine, fluorine atoms and nitro groups in its molecular structure, the molecular mass increases, and the intermolecular forces also change accordingly, resulting in a higher density. This property has a significant impact on the separation and purification process, and can be separated by methods such as liquid-liquid extraction due to density differences.
The melting point and boiling point of 2-iodine-3-fluoronitrobenzene are also characterized. The melting point is within a certain range, but it is roughly within a specific range due to the exact value depending on the measurement conditions and the purity of the sample. The boiling point is relatively high, which is due to the existence of various forces between molecules, such as van der Waals force, dipole-dipole interaction, etc. The electronegativity difference between iodine and fluorine atoms, as well as the strong electron absorption of nitro groups, increases the polarity of the molecules, and the intermolecular forces increase, thereby increasing the boiling point. The high boiling point characteristics make it necessary to carefully control the temperature during operations such as distillation to prevent the decomposition of the compound or other side reactions.
Furthermore, its solubility cannot be ignored. The compound exhibits some solubility in common organic solvents such as ethanol, ether, and dichloromethane. This is because the molecular structure of these organic solvents is similar to that of 2-iodine-3-fluoronitrobenzene, and follows the principle of "similarity and miscibility". In water, its solubility is extremely low, due to the large difference between the polarity of water and the molecular polarity of the compound, and the difficulty of forming effective interactions between molecules.
In addition, the volatility of 2-iodine-3-fluoronitrobenzene is relatively low. This is due to the large intermolecular force, and it is more difficult for molecules to escape from the liquid surface and enter the gas phase. Low volatility is an advantage during storage and use, which can reduce losses and environmental pollution caused by volatilization.
In summary, the physical properties of 2-iodine-3-fluoronitrobenzene, such as properties, density, melting point, solubility and volatility, are interrelated and affect their application in organic synthesis, analysis and detection and many other fields. Knowing and mastering these properties can make it better to use this compound for related research and practical work.
What is the chemistry of 2-Iodo-3-Fluoronitrobenzene?
2-Iodine-3-fluoronitrobenzene is one of the organic compounds. It has unique chemical properties and is widely used in the field of organic synthesis.
From the structural point of view, there are iodine atoms, fluorine atoms and nitro groups connected to the benzene ring of this compound. Iodine atoms have high nucleophilic substitution activity due to their large atomic radius and relatively dispersed electron cloud. When encountering nucleophilic reagents, iodine atoms are easily replaced. This characteristic makes 2-iodine-3-fluoronitrobenzene often used as an intermediate to construct carbon-carbon bonds or carbon-heteroatomic bonds.
Fluorine atoms are extremely electronegative, which can significantly affect the electron cloud density distribution of benzene rings. The electron-absorbing induction effect of the benzene ring will reduce the electron cloud density, especially in the adjacent and para-sites, which will affect the electrophilic substitution activity of the compound. And the introduction of fluorine atoms can change the physical and chemical properties of the compound, such as improving fat solubility, which is of great significance in the field of medicinal chemistry.
Nitro is also a strong electron-absorbing group, which greatly reduces the electron cloud density of the benzene ring, making the benzene ring more prone to nucleophilic substitution reactions and difficult to carry out electrophilic substitution reactions. The presence of nitro also enhances the oxidation of the compound. In some chemical reactions, nitro can be reduced to other groups such as amino groups, providing the possibility for the synthesis of diverse organic compounds.
In addition, 2-iodine-3-fluoronitrobenzene contains a variety of different active functional groups and can participate in a variety of chemical reactions, providing organic synthesis chemists with a rich strategy to prepare complex and functionally unique organic molecules. However, it should be noted that due to its iodine, fluorine and nitro groups, some reactions may require specific reaction conditions and catalysts to ensure reaction selectivity and yield.
What are 2-Iodo-3-Fluoronitrobenzene synthesis methods?
The synthesis of 2-iodine-3-fluoronitrobenzene is an important research topic in the field of organic synthesis. Several common synthesis paths are described in detail below.
First, fluorobenzene is used as the starting material. First, fluorobenzene is nitrified, and nitro groups are introduced into its benzene ring. This process requires careful selection of suitable nitrifying reagents, such as mixed acids of concentrated nitric acid and concentrated sulfuric acid. The reaction conditions, such as temperature and reaction time, are controlled so that the nitro group is precisely positioned in the ortho or meta-position of the fluorine atom to obtain 3-fluoronitrobenzene. Subsequently, the halogenation reaction is used to replace the hydrogen atom at a specific position on the benzene ring with an iodine reagent (such as iodine elemental substance, potassium iodide, etc.) under the action of a suitable catalyst (such as copper salt, etc.) to successfully synthesize 2-iodine-3-fluoronitrobenzene. The key to this route lies in the regioselectivity of the nitration reaction and the optimization of the halogenation reaction conditions to improve the yield and purity of the target product.
Second, nitrobenzene is used as the starting material. Nitrobenzene is first halogenated and fluorine atoms are introduced. Usually, 3-fluoronitrobenzene can be obtained by reacting with nitrobenzene with a fluorine-containing reagent under specific conditions by means of a nucle Then, 3-fluoronitrobenzene is iodized, and a suitable iodization method is selected. For example, iodine source is used for iodization under oxidation conditions, so that iodine atoms are connected to the benzene ring to achieve the purpose of synthesizing 2-iodine-3-fluoronitrobenzene. This approach needs to focus on the reaction conditions under which fluorine atoms are introduced, as well as the feasibility and selectivity of subsequent iodization reactions.
Third, it can also be synthesized by the strategy of constructing the benzene ring. For example, using appropriate small molecules containing fluorine, iodine and nitro-related substituents as raw materials, the benzene ring structure can be constructed through cyclization reaction. Although this method is more complex, it may have unique advantages in some cases for the synthesis of target products with specific substitution modes. However, this route involves multi-step reactions and complex reaction mechanisms, and very fine regulation of reaction conditions is required to ensure the smooth progress of the reaction and obtain high yields of 2-iodine-3-fluoronitrobenzene.
2-Iodo-3-Fluoronitrobenzene What are the precautions in storage and transportation?
2-Iodine-3-fluoronitrobenzene is also an organic compound. During storage and transportation, many matters must be paid attention to.
First words storage, this compound should be placed in a cool, dry and well ventilated place. Because of its certain chemical activity, high temperature and humid environment, it is easy to cause chemical reactions and cause its deterioration. Therefore, the warehouse temperature should be controlled in a specific range, not too high, and the humidity must also be suitable to prevent moisture dissolution and other conditions. In addition, it should be separated from oxidizing agents, reducing agents, alkalis and other substances. Due to its chemical properties, contact with their substances, or react violently, causing danger. The storage place should also be clearly marked, indicating its product name, nature and precautions, etc., for easy access and management.
As for transportation, it should not be underestimated. Transportation vehicles should ensure that the vehicle is in good condition and have corresponding protective measures. This compound needs to be properly packaged to prevent package damage and material leakage due to bumps and collisions. During transportation, avoid high temperature and open flames. During summer transportation, special attention should be paid to cooling, because high temperature can increase its reactivity and increase the danger. And transportation personnel should be professionally trained and familiar with the characteristics of this compound and emergency treatment methods. If there is an accident such as package damage on the way, it can be disposed of quickly and properly to avoid major disasters. In conclusion, the storage and transportation of 2-iodine-3-fluoronitrobenzene must be carried out with caution and strict compliance with regulations to ensure safety.