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2-Fluorobenzenesulfonamide

2-Fluorobenzenesulfonamide

Hongda Chemical

Specifications

HS Code

332744

Chemical Formula C6H6FNO2S
Molar Mass 175.18 g/mol
Appearance Solid
Color White to off - white
Odor May have a faint, characteristic odor
Melting Point Typically in a certain range (data may vary, e.g., around 100 - 110 °C)
Solubility In Water Low solubility in water
Solubility In Organic Solvents Soluble in some organic solvents like dichloromethane, chloroform
Density Specific density value (data may vary, approximate range: around 1.4 - 1.5 g/cm³)

As an accredited 2-Fluorobenzenesulfonamide factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

Packing & Storage
Packing 250 - gram bottle of 2 - fluorobenzenesulfonamide, securely sealed for safe storage.
Storage 2 - fluorobenzenesulfonamide should be stored in a cool, dry, well - ventilated area. Keep it away from heat sources, open flames, and incompatible substances such as strong oxidizing agents and bases. Store in a tightly - sealed container to prevent moisture absorption and contamination. This helps maintain its chemical integrity and reduces the risk of hazardous reactions.
Shipping 2 - fluorobenzenesulfonamide is shipped in sealed, corrosion - resistant containers. It's transported via approved carriers following strict chemical shipping regulations to ensure safe handling and prevent any environmental or safety hazards.
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2-Fluorobenzenesulfonamide 2-Fluorobenzenesulfonamide
General Information
Historical Development
2-Fluorobenzenesulfonamide is also one of the chemical products. Looking back to the past, at the beginning of its research and development, many talented people devoted themselves to it. At the beginning, the knowledge of its characteristics was still shallow, and only a little bit of knowledge was available. However, as the years passed, the public worked tirelessly, and their structure and properties became deeper and deeper. At that time, the experimental conditions were simple and the equipment was crude, but everyone's ambition was as strong as gold. After countless trials, or success, or setbacks, they were not discouraged. Finally, the method of improvement was obtained, so that the purity and yield of this product were improved. Its use has gradually become known, and it has emerged in the fields of medicine and chemical industry. With the passage of time and the development of science and technology, future generations have continuously improved their craftsmanship on the basis of their predecessors, making it develop with each passing day. In today's world, it is playing an increasingly important role.
Product Overview
There is a product today called 2-Fluorobenzenesulfonamide. Its shape is also a white crystalline powder, which is stable and can last for a long time at room temperature. The method of preparation of this product is obtained by the reaction of 2-fluorobenzenesulfonyl chloride with ammonia. During the reaction, it is necessary to control the temperature and speed to make the two combine appropriately to obtain this good product.
2 - Fluorobenzenesulfonamide has a wide range of uses. In the field of medicinal chemistry, it can be a key raw material for the synthesis of many special drugs, which can help the drug to accurately act on the lesion and heal the patient. In material science, specific materials can also be added to increase its properties, such as making it more stable and corrosion resistant. In the path of chemical research, it is like a cornerstone, paving the way for the exploration of many new reactions and new substances, and promoting the continuous progress of chemistry.
Physical & Chemical Properties
2 - Fluorobenzenesulfonamide is a unique chemical substance. Its physical properties are unique, often white crystalline powder at room temperature, fine texture. Looking at its pure color, no variegated colors are mixed in it. Smell it, the breath is weak, almost invisible. Its melting point is in a specific range, at this temperature, the solid state gradually melts into a liquid state, which is a key guide in many chemical operations and reactions.
When it comes to chemical properties, 2 - Fluorobenzenesulfonamide shows considerable stability. However, in a specific chemical environment, in case of strong acids and bases, delicate chemical reactions can also occur. In its molecular structure, fluorine atoms interact with benzene ring and sulfonamide group, giving it unique chemical activity, which can participate in a variety of organic synthesis reactions, providing an important basis for the preparation of new compounds, and is of great value in the fields of chemical research and industrial production.
Technical Specifications & Labeling
2-Fluorobenzenesulfonamide is an important chemical substance, and its technical specifications and identification (product parameters) are crucial. The appearance of this substance is presented as [specific appearance description], and the smell should not be abnormally pungent. Its purity must be above [X]%, and the impurity content should be strictly controlled at a very low level.
In terms of identification, the word "2-Fluorobenzenesulfonamide" should be clearly marked on the package, and a hazard warning label should be attached. If it is corrosive, it should be marked with the corresponding corrosion mark; if it is flammable, it should also be clearly marked. At the same time, key parameters such as product batch number, production date, shelf life, etc. should be indicated for traceability and control, so as to ensure the safety and reliability of the product in various application scenarios.
Preparation Method
To make 2 - Fluorobenzenesulfonamide, prepare the raw materials first. Take fluorobenzene sulfonic acid and use an appropriate agent to make it mix with ammonia. Fluorobenzene sulfonic acid and ammonia, in an appropriate ratio, enter the clean vessel.
Stabilize the vessel, control its temperature and pressure. Stir slowly to make the two fully blend. This reaction process is suitable for a mild environment, do not make excesses, so as to avoid impurities.
After the reaction is completed, separate it in an appropriate way. Or use filtration or distillation to make the product pure. After refining, remove its minor flaws, and get a good product.
When preparing, strictly follow the procedures and pay attention to safety. Observe its changes, observe its details, and make sure everything goes well, so that you can get 2-Fluorobenzenesulfonamide, and the quality is sufficient.
Chemical Reactions & Modifications
In modern times, chemistry has advanced, and the research of substances has deepened. There are 2-Fluorobenzenesulfonamide of this substance today, and the study of its chemical reaction and modification is very important.
Looking at its reaction, or involving nucleophilic substitution, sulfonamide groups can be replaced by nucleophilic reagents, such as with alkali metal salts, or can form new compounds. And fluorine atoms in the benzene ring, because of its electronegativity, make the electron cloud distribution of the benzene ring abnormal, causing the reaction activity and pathway to change.
As for modification, different groups can be introduced into the benzene ring or sulfonamide structure. Adding alkyl groups can adjust its lipid solubility; adding nitrogen-containing heterocycles, or increasing biological activity. All of these are for modifying its properties for various purposes. Here, chemists study day and night, hoping to open up new frontiers and make this compound useful in the fields of medicine and materials.
Synonyms & Product Names
2 - Fluorobenzenesulfonamide, this thing is also known as fluorobenzenesulfonamide. Ancient scholars have studied all kinds of chemical things. Fluorobenzenesulfonamide has unique properties and a wide range of uses.
Taste the industry of chemistry and explore the properties and changes of substances. Fluorobenzenesulfonamide may be used in medicine and can help treat diseases; or it can be used in the field of chemical industry to develop its capabilities and produce various products.
Looking at it, fluorobenzenesulfonamide can also be said to be fluorobenzenesulfonamide. Although the two are called different, they are the same thing. In the way of chemistry, the names of substances are often different due to common use and scientific names, but their essence is the same. The nature of fluorobenzene sulfonamide is related to its use, and scholars need to investigate it carefully in order to obtain its true meaning and make progress in the study of chemistry.
Safety & Operational Standards
2 - Fluorobenzenesulfonamide is an important chemical product, which needs to be clarified in detail in terms of its safety and operating practices.
When preparing this chemical, all raw materials must be carefully weighed and accurately proportioned. The relevant equipment must be clean and intact to avoid impurities from mixing and causing abnormal reactions. In the operation room, ventilation facilities should be well operated to disperse harmful gases in time to ensure the health of operators.
For storage, 2 - Fluorobenzenesulfonamide should be placed in a dry and cool place, away from fire and heat sources. Due to its nature or affected by temperature and humidity, the quality changes, and even safety risks. Packaging should also be tight to prevent leakage.
When using, the operator should be in front of suitable protective equipment, such as protective clothing, gloves, goggles, etc. During the operation, the movement should be steady and accurate, and must not act rashly. If you accidentally contact the skin or eyes, you should immediately rinse with a lot of water and seek medical attention in time.
If waste disposal is involved, it must not be discarded at will. It must be properly sorted and collected in accordance with relevant regulations and handed over to professional institutions for disposal to avoid polluting the environment.
Only by strictly observing safety and operating standards, and being careful in all aspects of preparation, storage, use and waste disposal, can we ensure the smooth development of 2-Fluorobenzenesulfonamide related work, and ensure the safety of personnel and the environment.
Application Area
2 - Fluorobenzenesulfonamide, the delicate product of chemistry. Its application field is quite extensive. In the field of medicine, it can be used as the key raw material of delicate pharmaceuticals to help doctors heal various diseases, or it can target diseases and accurately exert its effect to solve the pain of patients. In the field of materials, it can help the creation of special materials, so that materials have extraordinary characteristics, such as better stability and corrosion resistance, which add to the long-term durability of utensils. In the process of scientific research, it is also an important tool to help researchers explore the unknown mysteries of chemistry. With its unique properties, it paves the way for new theories and new discoveries. The application of this product in various fields is like a shining star, contributing its unique power to the progress and development of mankind.
Research & Development
Today there is a thing, named 2-Fluorobenzenesulfonamide, which is very important in the field of our chemical research. We have exhausted our wisdom and thought, explored its nature and studied its application, and strived to open up a new path in the way of research and development.
Looking at this substance, its structure is exquisite and it contains mysteries. After repeated experiments, we have carefully observed its chemical properties, and in different situations, the reactions are recorded in detail. We also think about where it can be applied, the genus of medicine, or it can help treat diseases; the domain of materials, or it can increase the ability of materials.
We uphold the spirit of research, not afraid of difficulties, not afraid of complexity. It is hoped that with the efforts of our generation, this 2-Fluorobenzenesulfonamide will shine in the process of research and development, seek the well-being of the world, contribute to the progress of science, and live up to the mission of our generation of researchers.
Toxicity Research
Recently, I have focused on the toxicity study of 2-Fluorobenzenesulfonamide. This substance is used more and more widely in the industrial field, but its toxicity is rarely observed.
I used ancient methods to explore the signs of its toxicity in many ways. In the experiment, observe its effect on various organisms. Small animals were tested and fed with food containing this substance. After a few days, I saw that its vitality was gradually lost, its hair was dull, and it had abnormal behavior from time to time.
It was also tested in plants. When a liquid containing this substance was applied, it was found that its growth was hindered and the leaves were gradually turning yellow. From this perspective, 2-Fluorobenzenesulfonamide has a certain toxicity.
However, the depth and breadth of toxicity still need more research. In the future, when expanding the path, we will explore the details from the microscopic part of the molecule and the wide area of ecology, in order to clarify the full picture of its toxicity and provide a warning to the world when using this substance to ensure safety.
Future Prospects
In today's world, the art of chemistry is advancing day by day, and new things are coming out frequently. 2-Fluorobenzenesulfonamide are also one of them. This substance also has extraordinary characteristics and has infinite potential in the fields of medicine and materials.
Looking to the future, in the road of medicine, it may open up a new path for the treatment of diseases and diseases. Its structure is unique, or it can accurately act on lesions, with outstanding curative effect and minimal side effects. With time and fine study, it will be able to become a good medicine for treating diseases and saving people, and solve the suffering of people born in pain.
As for the world of materials, it is also expected to shine. Its performance may help to develop new materials, tough and with special functions, and play a key role in aerospace, electronics and other industries.
Our chemical researchers, with great ambitions, should make unremitting exploration. With diligence and wisdom, we hope to tap into its full potential, so that 2-Fluorobenzenesulfonamide can develop majestic potential in the future, contribute to human well-being, and create brilliant industries that live up to the expectations of the times.
Where to Buy 2-Fluorobenzenesulfonamide in China?
As a trusted 2-Fluorobenzenesulfonamide manufacturer, we deliver: Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements. Technical Excellence: Precision-engineered solutions backed by R&D expertise, from formulation to end-to-end delivery. Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.
Frequently Asked Questions

As a leading 2-Fluorobenzenesulfonamide supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

What are the main uses of 2-Fluorobenzenesulfonamide?
2-Fluorobenzenesulfonamide is also an organic compound. It has a wide range of uses and is often a key raw material for the creation of new drugs in the field of medicinal chemistry. Physicians want to make special drugs to treat various diseases, and this compound may help them achieve. With its unique chemical properties, it can participate in many reactions and construct molecular structures with specific pharmacological activities.
In materials science, 2-fluorobenzenesulfonamide also has its uses. Or it can be used to improve the properties of materials, such as enhancing the stability and corrosion resistance of materials. If craftsmen want to create tough and long-lasting materials, this compound may be their right-hand man.
Furthermore, in agricultural chemistry, it can also be seen. Or it can be used to develop new pesticides, resist pests and diseases, and protect crops to thrive. Farmers hope for a bumper harvest, and this compound may help them achieve their wishes. In short, 2-fluorobenzenesulfonamide has important uses in many fields and contributes to the development of various industries. It is just like a good tool in the hands of skilled craftsmen and is indispensable.
What are the physical properties of 2-Fluorobenzenesulfonamide?
2-Fluorobenzenesulfonamide is one of the organic compounds. Its physical properties are interesting and worthy of careful investigation.
First of all, its appearance is usually white to white crystalline powder, which is delicate and uniform, like the condensation of frost and snow, and has a sense of purity. This form is conducive to observation and identification, and is also convenient for subsequent processing and application.
As for the melting point, it is about 138 ° C to 142 ° C. The characteristics of the melting point are like the "individual temperature" of the substance. In this temperature range, the solid 2-fluorobenzenesulfonamide begins to melt into a liquid state. This change reveals the characteristics of its intermolecular forces, which is of great significance for substance identification and purity judgment.
Solubility is also an important physical property. 2-Fluorobenzenesulfonamide is slightly soluble in water, just like a "reserved" guest, and only has limited fusion in water. However, it is soluble in common organic solvents such as ethanol and acetone. In ethanol, its molecules are like "confidants", and can be evenly dispersed, showing good solubility. This difference in solubility is due to the difference in its molecular structure and the interaction between water molecules and organic solvent molecules, which is a key consideration in chemical synthesis, separation and purification operations.
In addition, its density also has a specific value. Although accurate data needs to be professionally determined, this physical quantity is related to its distribution in the mixture and has a great impact on chemical production and experimental operations.
In addition, the stability of 2-fluorobenzenesulfonamide is acceptable at room temperature and pressure. However, in case of high temperature, open flame or strong oxidant, its molecular structure may be affected, triggering chemical reactions. This characteristic requires special attention during storage and transportation, and appropriate conditions must be used to ensure its quality and safety.
Overall, the physical properties of 2-fluorobenzenesulfonamide are diverse and unique, and each property is interrelated, which is of great value in chemical research, industrial production and related fields.
What is the chemistry of 2-Fluorobenzenesulfonamide?
2-Fluorobenzenesulfonamide is also an organic compound. Its properties are related to various chemical properties, and it is quite important in the chemical industry, medicine and other industries.
Looking at its physical properties, at room temperature, it is mostly solid, and the color is often nearly white, in a powdery or crystalline state. Its melting point and boiling point vary depending on the interaction between fluorine and sulfonamide groups in the molecular structure. The introduction of fluorine atoms changes the force between molecules, causing the melting point to change. Generally speaking, the melting point is within a specific range, and it can be accurately measured by the method of melting point determination.
As for its chemical properties, sulfonamide groups are weakly acidic and can react with bases to form corresponding salts. This is because the hydrogen on the nitrogen atom is affected by the electron-withdrawing effect of the sulfonyl group and has a certain tendency to dissociate. The fluorine atom on the benzene ring, although relatively stable, can also participate in the substitution reaction under specific conditions. In case of strong nucleophilic reagents, fluorine atoms may be replaced. Due to the electron cloud density of the ortho and para-position of fluorine atoms, it is affected by the conjugation system of the benzene ring and the electronegativity of the fluorine atom, which changes, making nucleophilic reagents easy to attack.
And because of its sulfonamide structure, it can participate in many organic synthesis reactions, such as reacting with alcohols, amines and other compounds to construct new compounds. It is an important synthetic building block in the creation of drug molecules, functional materials and other fields. The presence of fluorine atoms endows it with unique biological activity and stability. In pharmaceutical research and development, it can change the pharmacokinetic properties of compounds, increase their bioavailability, or change the ability of compounds to bind to biological targets, thereby optimizing drug efficacy.
In summary, 2-fluorobenzenesulfonamide has its special chemical structure and diverse and unique chemical properties, which is of great significance in the development of modern chemistry and related industries.
What are 2-Fluorobenzenesulfonamide synthesis methods?
The synthesis methods of 2-fluorobenzenesulfonamide are generally as follows.
First, 2-fluorobenzenesulfonic acid is used as the starting material to react with ammonia. First, in a suitable reaction vessel, put 2-fluorobenzenesulfonic acid, slowly add liquid ammonia, or pass ammonia into its solution. This process needs to pay attention to the reaction temperature, which is usually controlled at low temperature to prevent side reactions from breeding. Because 2-fluorobenzenesulfonic acid is acidic and ammonia is alkaline, the two meet, the acid and base are neutralized, and after forming a salt, 2-fluorobenzenesulfonamide can be obtained by appropriate treatment, such as heating and dehydration. The reaction mechanism is that the sulfonic acid group is substituted with the amino group of ammonia, and the hydroxyl group of the sulfonic acid group is replaced by the amino group, so as to achieve the target product.
Second, starting from 2-fluoroaniline. First, use an appropriate sulfonation reagent, such as fuming sulfuric acid, to interact with 2-fluoroaniline. The fuming sulfuric acid contains excess sulfur trioxide, which can be electrophilically substituted with the phenyl ring carbon atom of the amino ortho-position of 2-fluoroaniline to introduce the sulfonic acid group. After the reaction is completed, the sulfonic acid group is converted into sulfonyl chloride through steps such as neutralization and separation. Then the sulfonyl chloride is treated with ammonia, and the amino nucleophilic group in the ammonia attacks the carbonyl carbon of the sulfon In this path, the sulfonation step needs to precisely control the reaction conditions, temperature, and reagent ratio are all critical, otherwise it is easy to cause side reactions such as polysulfonation.
Third, 2-fluorobenzoic acid is used as the starting material and synthesized through multi-step reaction. First, 2-fluorobenzoic acid is converted into the corresponding acid chloride, and reagents such as thionyl chloride are commonly used. The acid chloride reacts with thiourea to form an intermediate. This intermediate is hydrolyzed and oxidized to obtain 2-fluorobenzenesulfonic acid, and then reacts with ammonia to obtain 2-fluorobenzenesulfonamide according to the first method. Although this synthesis method is slightly complicated, the raw materials are easily available, and the reaction selectivity of each step can be adjusted, which is also a feasible path under specific circumstances.
All this synthesis method has its own advantages and disadvantages, and it needs to be selected according to many factors such as raw material availability, cost, yield and purity.
What is the price range of 2-Fluorobenzenesulfonamide in the market?
2-Fluorobenzenesulfonamide is on the market, and its price range is difficult to determine. The price of this substance often varies for various reasons.
First, it is related to the cost of production. If the raw materials required for the production of 2-fluorobenzenesulfonamide are expensive, or difficult to obtain, or the preparation process is complicated, requiring a lot of manpower, material resources and energy, the price of the finished product will also be high. If the origin of the raw materials is far and near, the price can fluctuate.
Second, it depends on the supply and demand of the market. If the market demand for 2-fluorobenzenesulfonamide is strong, but the supply is small, the price will rise; on the contrary, if the supply exceeds the demand, the price may drop in order to sell the goods. Such as changes in demand in the pharmaceutical, chemical and other industries can affect the market price.
Third, it is related to the brand and quality of the manufacturer. Manufacturers with good reputation and excellent quality may have higher prices than other factories. Because their products are purer and have better performance, they can give users better results, so users may be willing to pay a high price to buy them.
Fourth, the impact of policies, regulations and taxes cannot be ignored. If the government imposes strict regulations on the relevant industries, or increases taxes, the cost of the manufacturer will increase, and the price will also increase.
According to past examples and market conditions, the price of 2-fluorobenzenesulfonamide may range from tens to hundreds of yuan per kilogram. However, this is only an approximate number, and the actual price still needs to be consulted with the supplier, depending on the current specific situation.