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2-Fluorobenzene-1,4-Dicarbonitrile

2-Fluorobenzene-1,4-Dicarbonitrile

Hongda Chemical

Specifications

HS Code

491351

Chemical Formula C8H3FN2
Molecular Weight 146.12 g/mol
Appearance Solid (predicted)
Solubility In Water Insoluble (predicted)
Solubility In Organic Solvents Soluble in common organic solvents (predicted)
Logp 1.67 (predicted)

As an accredited 2-Fluorobenzene-1,4-Dicarbonitrile factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

Packing & Storage
Packing 250 - gram bottle of 2 - fluorobenzene - 1,4 - dicarbonitrile, well - sealed for protection.
Storage 2 - Fluorobenzene - 1,4 - dicarbonitrile should be stored in a cool, dry, well - ventilated area. Keep it away from sources of heat, ignition, and oxidizing agents. Store in a tightly - sealed container, preferably made of corrosion - resistant materials. This helps prevent decomposition, potential reactions, and ensures the chemical's stability during storage.
Shipping 2 - Fluorobenzene - 1,4 - dicarbonitrile is shipped in well - sealed containers. It must comply with hazardous chemical shipping regulations, ensuring proper labeling, handling, and transportation to prevent spills and ensure safety during transit.
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2-Fluorobenzene-1,4-Dicarbonitrile 2-Fluorobenzene-1,4-Dicarbonitrile
General Information
Historical Development
2-Fluorobenzene-1,4-dinitrile is also an organic compound. At the beginning, the research of all scholars sought the method of its synthesis. At the beginning, the technology was not refined, the synthesis was difficult, and the yield was quite low. However, the heart of a scholar is as firm as a golden stone, and he is unremitting in his pursuit of progress.
As time goes by, science and technology are new, and the technology of chemistry is also greatly advanced. The new reaction mechanism is clear, and new reagents and new methods have emerged one after another. The road to synthesizing 2-fluorobenzene-1,4-dinitrile has gradually become smooth. The yield has gradually risen from the low level in the past to a considerable level.
And its use is also valued by scholars. Today, 2-fluorobenzene-1,4-dinitrile is not a rare thing in the past, and its research and application are expanding day by day, with a bright future, adding a bright color to the development of chemistry.
Product Overview
Today there is a substance called 2 - Fluorobenzene - 1,4 - Dicarbonitrile. This is an important raw material for organic synthesis and is widely used in many fields. Its shape may be crystalline, its color may be pure.
This substance has a delicate structure. On the benzene ring, the fluorine atom is cleverly connected to the dinitrile group, giving it unique properties. Due to the high electronegativity of fluorine atoms, it affects the polarity and reactivity of molecules; the existence of dinitrile groups also lays the foundation for its participation in various reactions.
In synthetic chemistry, it is often used as a key intermediate, and various compounds with unique functions can be derived through many reaction paths. The balance of its stability and reactivity allows chemists to skillfully design and construct complex molecular architectures according to demand, with promising applications in cutting-edge fields such as materials science and drug development.
Physical & Chemical Properties
2 - Fluorobenzene - 1,4 - Dicarbonitrile is an important organic compound. Its physicochemical properties have attracted much attention. The melting point of this compound has been experimentally determined to be within a specific range, reflecting the characteristics of its intermolecular forces. Its boiling point is also a key physical property, which is related to its phase transition at different temperatures.
In terms of chemical properties, the cyanyl group and fluorine atoms it contains give it unique reactivity. Cyanyl groups can participate in a variety of nucleophilic substitution and addition reactions, and the electronegativity of fluorine atoms affects the electron cloud distribution of molecules, causing it to behave differently in electrophilic substitution reactions. The study of these physical and chemical properties will help to understand the potential applications of this compound in the fields of organic synthesis and materials science, and lay the foundation for subsequent research and development.
Technical Specifications & Labeling
Today there are 2 - Fluorobenzene - 1,4 - Dicarbonitrile, which is very important for our chemical research. In terms of its technical specifications and identification (product parameters), it needs to be carefully studied.
Its quality should be pure, and impurities must be slight. This is the first rule. Looking at its shape, it should be [specific appearance description], pure color and no variegation. Measuring its melting point should be in the [specific melting point range], and the boiling point should be in the [specific boiling point range], which is the key to determining its purity and characteristics.
On the label, the name should be "2 - Fluorobenzene - 1,4 - Dicarbonitrile", and a warning should be attached to inform everyone of its characteristics and use it with caution. Mark its molecular weight and formula to make it clear to the viewer its chemical composition. In this way, the combination of technical specifications and labels is beneficial for research and production.
Preparation Method
To prepare 2 - Fluorobenzene - 1, 4 - Dicarbonitrile, first take fluorobenzene as the raw material, with bromine and iron powder as the help, so that the bromine should be brominated to obtain 4 - bromo - 2 - fluorobenzene. Following the co-heating of cuprous cyanide with it, in a high temperature closed device, the bromine is cyanosubstituted to produce 4 - cyano - 2 - fluorobenzene.
Take another 4 - cyano - 2 - fluorobenzene, prepare it in a suitable solvent, add a catalyst, at a specific temperature, pass an appropriate amount of cyanide reagent, and then cyanide, control the reaction process, and monitor it in a timely manner. To be completed, after separation and purification, chromatography and crystallization methods are used to remove heterozygous and keep pure, and finally 2-Fluorobenzene-1,4-Dicarbonitrile is obtained. The method of this system must abide by the procedures, control the temperature, time and amount of agent to ensure the quality and quantity of production.
Chemical Reactions & Modifications
There is now a substance, named 2 - Fluorobenzene - 1,4 - Dicarbonitrile. I am a chemical researcher, often studying chemical reactions and modifications.
The chemical reaction of this substance is related to its structure and characteristics. Its fluorine atom and cyano group are both active and can initiate various reactions. Such as nucleophilic substitution, fluorine atoms can be replaced by other groups. Due to the strong electronegativity of fluorine, it is favorable for nucleophilic reagents to attack. This reaction can introduce new functional groups and expand molecular structures in organic synthesis.
When it comes to modification, its properties can be adjusted by chemical reactions. Or change its solubility to suit different solvent systems; or adjust its stability to meet different environmental requirements. The method of modification is to finely manipulate the reaction conditions to obtain the desired characteristics of the molecule.
Our researchers often explore the theory and increase their understanding in the field of chemistry, in order to create more possibilities with this material and benefit many fields.
Synonyms & Product Names
2-Fluorobenzene-1,4-dinitrile, this substance is very important in chemical research. It has many synonyms and is also called differently in the industry due to its uses and characteristics.
In past literature, or see the name related to its characteristics, such as according to its fluorine-containing and nitrile-based structure, it is called by the name of structural association. As for the product name, the manufacturer names it in recognition of its characteristics, or in combination with the production process and intended use.
Because the chemical industry is constantly evolving, the title also changes with the times. The name used in the past may be easier due to new discoveries and new uses. However, no matter how the name changes, it refers to the substance of 2-fluorobenzene-1,4-dinitrile. Its value in chemical research has never been reduced. Researchers all know that its essence is the same, although the name is different, it is the same.
Safety & Operational Standards
2 - Fluorobenzene - 1,4 - Dicarbonitrile Safety and Practice
Husband 2 - Fluorobenzene - 1,4 - Dicarbonitrile is an important compound in chemical research. During its experimental operation, safety is the first priority, and the operation standard is also indispensable.
In terms of safety, this compound has a certain latent risk. Its physical and chemical properties determine that it needs to be careful to avoid direct contact with the human body. If you accidentally touch the skin, rinse with plenty of water as soon as possible and seek medical treatment as appropriate. As for eye access, you must immediately rinse with flowing water or normal saline, and do not delay, and then you need to seek medical help urgently.
Before the experiment, the physicochemical characteristics must be known in detail. When operating, it should be carried out in a well-ventilated experimental environment to avoid the accumulation of harmful gases. The experimental equipment used must be clean and dry to prevent impurities from affecting the experimental results and damage to the equipment. To weigh the compound, precise equipment is required to ensure that the dosage is correct.
Furthermore, storage also has its own rules. Store 2 - Fluorobenzene - 1,4 - Dicarbonitrile in a cool, dry and ventilated place, away from fire and heat sources, to prevent dangerous changes. At the same time, it should be separated from oxidizing agents, acids and other substances to avoid mutual reaction.
In conclusion, in the research and use of 2-Fluorobenzene-1, 4-Dicarbonitrile, strict adherence to safety and operating standards is required to obtain accurate experimental results and ensure the safety of experimenters.
Application Area
2-Fluorobenzene-1,4-dinitrile has a wide range of application fields. In the field of medicinal chemistry, it can be used as a key intermediate to help synthesize many drugs with special curative effects. Due to its unique chemical structure, it can accurately participate in specific reactions, laying the foundation for the creation of novel drug molecules.
In the field of materials science, it has also made a name for itself. With its characteristics, it can be used to prepare high-performance organic optoelectronic materials. After rational design and synthesis, it can significantly optimize the photoelectric properties of materials, such as improving their luminous efficiency and stability, and has potential application value in cutting-edge technologies such as organic Light Emitting Diode (OLED).
Furthermore, in the production of fine chemicals, it can be used as a core raw material to generate a series of high-value-added fine chemicals to meet the needs of different industries for special chemicals, and to promote the chemical industry towards high-end and refinement.
Research & Development
There is now a thing called 2 - Fluorobenzene - 1,4 - Dicarbonitrile. We are exploring the path of its research and creation with the heart of researchers. The properties of this thing are related to chemistry, and it has profound implications for reaction mechanisms and synthesis paths.
We study the past, looking for traces of its beginnings, and observing the methods used by predecessors, or there are some problems. So we think about improving it, and use modern techniques to achieve better synthesis. Looking at its structure, the position of fluorine and dinitrile groups affects physical properties and reactivity.
The process of research takes into account factors such as temperature, solvent, and catalyst. The temperature is related to the reaction rate and product purity; the choice of solvent affects the dissolution of substances and the reaction environment; the choice of catalyst can change the process of chemical reaction. After repeated attempts to optimize conditions and achieve high yield, this substance can be used in scientific research, industry and other fields to develop its growth, so as to help the industry advance and seek future development.
Toxicity Research
To study the toxicity of 2 - Fluorobenzene - 1,4 - Dicarbonitrile. Looking at its molecular structure, it contains fluorine and cyano groups, both of which are often toxic. From the experimental point of view, it does have adverse effects on organisms. In animal experiments, after exposure to this substance, the tested animals often have abnormal physiological functions. Or behavioral changes, such as reduced activity, abnormal eating; or internal organs are diseased, with signs of impaired liver and kidney function. And at the cellular level, it can cause cell morphological changes and metabolic disorders. All this indicates that 2 - Fluorobenzene - 1,4 - Dicarbonitrile has significant toxicity. In the future, it is necessary to study its toxicological mechanism in order to clarify its role in the biological body, and to find the basis for the protection and detoxification method to protect all living beings from its harm.
Future Prospects
I have dedicated myself to the study of chemical substances, and recently focused on the product 2 - Fluorobenzene - 1,4 - Dicarbonitrile. Looking at its characteristics, observing its performance, I feel that it contains unlimited potential.
The future prospect of the husband, this product may shine in the field of materials. Its unique structure may create novel functional materials for use in electronic devices, which can improve its performance and make operation more efficient and stable. In the field of energy, it may be the cornerstone of new energy storage materials, helping energy storage and conversion, and promoting the development of new energy.
Or emerging in the road of drug research and development. With its special chemical properties, it may become a key synthetic intermediate to develop drugs with better curative effects and fewer side effects for the benefit of the common people.
Although there is a long way to go, I firmly believe that with time and in-depth investigation, 2 - Fluorobenzene - 1,4 - Dicarbonitrile will be able to demonstrate its extraordinary value, contribute to future development, and lead many fields to new heights.
Where to Buy 2-Fluorobenzene-1,4-Dicarbonitrile in China?
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Frequently Asked Questions

As a leading 2-Fluorobenzene-1,4-Dicarbonitrile supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

What is the main use of 2-Fluorobenzene-1,4-Dicarbonitrile?
2-Fluorobenzene-1,4-dinitrile has a wide range of uses. In the field of organic synthesis, it is often used as a key intermediate. Due to its unique structure, the fluorine atom and dinitrile group give it special chemical activity.
When creating new materials, 2-fluorobenzene-1,4-dinitrile is very useful. For example, the preparation of high-performance polymers, which can use their own structure to cleverly react with other monomers to polymerize to form polymer materials with special properties. These materials may have excellent heat resistance and mechanical properties, and can be used in high-end fields such as aerospace and electronic devices.
In the field of medicinal chemistry, it cannot be ignored. Due to its special chemical properties, it can become an important starting material for the design and synthesis of new drugs. Modified by a series of chemical reactions, or compounds with specific biological activities can be obtained, which is expected to develop specific drugs for some diseases.
Furthermore, in materials science, when it comes to the development of optical materials, 2-fluorobenzene-1,4-dinitrile can also play a role. Its structure affects the electron cloud distribution of molecules, which in turn affects the optical properties of materials, or can be used to prepare optically related products such as luminescent materials.
To sum up, 2-fluorobenzene-1,4-dinitrile is an indispensable and important substance in many fields such as organic synthesis, medicinal chemistry, and materials science. It has a wide range of uses and is critical.
What are the physical properties of 2-Fluorobenzene-1,4-Dicarbonitrile?
2-Fluorobenzene-1,4-dinitrile, this is an organic compound. Its physical properties are as follows:
Looking at its shape, under normal conditions, it is mostly white to light yellow crystalline powder, just like fine snow grains, fine in texture, and its slight luster may be seen under light.
When it comes to the melting point, it is about [specific melting point value] ℃. When the temperature gradually rises, the substance slowly melts from a solid state to a liquid state, just like ice and snow melting, and realizes the transformation of the state of matter at a specific temperature node.
In terms of boiling point, under specific pressure conditions, it can reach [specific boiling point value] ℃. At this temperature, it will vaporize violently in the liquid state and turn into a gaseous state.
Solubility is also a key property. In organic solvents, such as common N, N-dimethylformamide (DMF), dichloromethane, etc., it exhibits good solubility and can be mutually soluble with it to form a uniform and stable solution, which is as natural as salt merging into water. However, in water, the solubility is very small. Due to its molecular structure characteristics, it is difficult to form effective interactions with water molecules, so it is difficult to dissolve in water, just like oil floating on the water surface, and it is distinct.
In addition, its density is also an important parameter, about [specific density value] g/cm ³, which determines its floating state and other characteristics in different media. Its vapor pressure is relatively low at room temperature, which means that in a normal environment, it has a small tendency to evaporate into the air, and its chemical stability is relatively high. It is not easy to lose or undergo other chemical changes due to volatilization. It is like a stable person and is not easily disturbed by the outside world.
What are the chemical properties of 2-Fluorobenzene-1,4-Dicarbonitrile?
2-Fluorobenzene-1,4-dinitrile is one of the organic compounds. It has unique chemical properties and is widely used in the field of organic synthesis.
In terms of its chemical properties, the introduction of fluorine atoms changes the electron cloud distribution of the compound. Fluorine has strong electronegativity and can absorb electrons, causing the electron cloud density of the benzene ring to decrease, which affects the electrophilic substitution reaction. The electron cloud density of the adjacent and para-position on the benzene ring is slightly higher than that of the benzene derivatives without fluorine substitution, but the overall electrophilic substitution activity is still lower. When encountering electrophilic reagents, the substitution reaction is mostly in the adjacent and para-position, but it is difficult to occur in the non-fluorine substitution.
The nitrile group (-CN) is another important functional group of this compound. The nitrile group is polar and can participate in a variety of reactions. First, it can hydrolyze to form carboxylic acids or their derivatives, which can occur under acidic or alkaline conditions. In acidic media, hydrolysis of amide intermediates finalizes in carboxylic acids; under alkaline conditions, the hydrolysis rate is faster or faster to form carboxylic salts, and after acidification, carboxylic acids are obtained. Second, the nitrile group can be reduced, and common reducing agents such as lithium aluminum hydride (LiAlH) can reduce the nitrile group to primary amines, which is an important way to prepare amino-containing compounds.
2-fluorobenzene-1,4-dinitrile has a certain balance of chemical stability and reactivity due to its fluorine and nitrile groups. In the field of materials science, it may be used as a monomer for the synthesis of polymer materials with special properties; in pharmaceutical chemistry, it can use its unique chemical properties to modify lead compounds to improve drug activity, selectivity and metabolic stability. In short, 2-fluorobenzene-1,4-dinitrile has unique chemical properties and great potential in organic synthesis and related fields. It can provide a key building block for the development of new materials and new drugs.
What are the synthesis methods of 2-Fluorobenzene-1,4-Dicarbonitrile?
The synthesis method of 2-fluorobenzene-1,4-dinitrile is related to the technology in the field of organic synthesis. One of the common methods is to use fluorobenzene derivatives as starting materials and obtain them by cyanylation. For example, 2-fluoro terephthalic acid can be heated with ammonia and dehydrating agent, ammonia interacts with carboxyl groups, and the carboxyl group is converted into cyanide after dehydration, and then 2-fluorobenzene-1,4-dinitrile is formed through this step. This process requires fine temperature control, and the choice of dehydrating agent is also very critical. The activity and selectivity of different dehydrating agents will affect the yield and purity of the product.
Furthermore, halogenated aromatics can also be used. First, 2-fluoro-1,4-dihalobenzene is used as the substrate to react with cyanide reagents, such as cuprous cyanide or potassium cyanide, under suitable catalysts and reaction conditions. The catalyst can be selected as a palladium or nickel catalyst to activate the carbon-halogen bond in halogenated aromatics to promote the cyanide substitution reaction. In this path, the properties of the solvent, the reaction time and temperature have a significant impact on the reaction process and results. Appropriate solvents can enhance the solubility and mass transfer efficiency of the reactants, and appropriate reaction time and temperature can ensure sufficient reaction and minimal side reactions.
In addition, the reaction involving organometallic reagents is also a way. For example, Grignard's reagent or lithium reagent reacts with the corresponding fluorine-containing aryl halide to form an organometallic intermediate, and then reacts with a cyanyl source to introduce a cyanyl group. This process requires strict anhydrous and anaerobic conditions in the reaction environment, otherwise the organometallic reagent is easily reacted with water or oxygen and deactivated, resulting in reaction failure. And the steps of preparing organometallic reagents also need to be carefully handled to ensure their activity and stability. All kinds of synthesis methods have their own advantages and disadvantages, and they need to be selected according to actual needs and conditions.
2-Fluorobenzene-1,4-Dicarbonitrile What are the precautions during use?
2-Fluorobenzene-1,4-dinitrile is also used in chemical affairs. In the process of its use, several things should be taken into account.
First, this substance is toxic and irritating, and can harm the body by touching it, smelling it or eating it. Therefore, when using it, you must wear protective clothing, gloves, goggles, etc., to avoid direct contact with it. And in a well-ventilated place to prevent its gas from entering the body.
Second, 2-fluorobenzene-1,4-dinitrile is chemically active, and can be explosive and flammable in case of fire, hot topic or strong oxidant. When storing, avoid fire and heat sources, and do not mix with oxidants. When operating, avoid open flames and hot topic sources.
The three, their properties in the reaction, also need to be known in detail. Different reaction conditions, such as temperature, pressure, and catalyst differences, can cause the reaction to change. Therefore, before use, it is necessary to understand the appropriate reaction environment to obtain good results. And in the reaction process, observe the reaction situation, if there is any abnormality, take measures quickly.
Furthermore, the waste of 2-fluorobenzene-1,4-dinitrile should not be ignored. It should not be discarded indiscriminately. It should be handled in accordance with relevant regulations and in accordance with environmental protection laws to avoid polluting the environment.
In short, the use of 2-fluorobenzene-1,4-dinitrile should be safe, clear, careful, and suitable for waste. In this way, the process of use can be guaranteed to be safe and smooth, harmless to the body, and free of pollution.