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2-​Fluoro-​6-​(Trifluoromethyl)​Benzenemethanamine

2-​Fluoro-​6-​(Trifluoromethyl)​Benzenemethanamine

Hongda Chemical

    Specifications

    HS Code

    391368

    Chemical Formula C8H7F4N
    Molar Mass 193.14 g/mol
    Appearance Typically a colorless to pale - yellow liquid or solid (depending on temperature)
    Boiling Point Data may vary, but generally in the range related to its molecular structure and intermolecular forces
    Melting Point Varies, needs experimental determination
    Solubility In Water Poorly soluble in water due to non - polar aromatic and fluorinated groups
    Solubility In Organic Solvents Soluble in common organic solvents like dichloromethane, chloroform, etc.
    Density Density value depends on the state and conditions, related to its molar mass and molecular packing
    Vapor Pressure Relatively low vapor pressure due to its molecular weight and structure
    Flash Point Requires experimental determination for safety handling, related to its flammability

    As an accredited 2-​Fluoro-​6-​(Trifluoromethyl)​Benzenemethanamine factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing 500g of 2 - fluoro - 6 - (trifluoromethyl)benzenemethanamine in sealed chemical - grade containers.
    Storage 2 - Fluoro - 6 - (trifluoromethyl)benzenemethanamine should be stored in a cool, dry, well - ventilated area, away from heat sources and open flames. It should be kept in a tightly sealed container to prevent exposure to air and moisture. Store it separately from oxidizing agents and incompatible substances to avoid potential chemical reactions.
    Shipping 2 - fluoro - 6 - (trifluoromethyl)benzenemethanamine is shipped in accordance with strict chemical regulations. Packed in suitable containers, it's transported with care to ensure safety during transit to the destination.
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    2-​Fluoro-​6-​(Trifluoromethyl)​Benzenemethanamine 2-​Fluoro-​6-​(Trifluoromethyl)​Benzenemethanamine
    General Information
    Historical Development
    At the beginning of the research and development of the past, 2 - Fluoro - 6 - (Trifluoromethyl) Benzenemethanamine was not seen in the world. All researchers worked hard, hoping to create something. At the beginning, the raw materials were rare, the techniques were unripe, and the progress was difficult. However, the crowd worked tirelessly, searching for ancient books, and trying new paths again and again.
    After several years, there was a slight breakthrough. Can make a small amount, observe its properties, test its properties. After repeated improvements, the process is gradually refined, and the output is also increased.
    With the passage of time, its use has gradually become apparent, and it has emerged in the fields of medicine and other fields. The work of the researcher has made this product famous from unknown to brilliant, and it will be used by future generations. It is really beneficial for the progress of science and technology. The difficult research and development path in the past has created today's achievements, which is also a lesson for future generations.
    Product Overview
    Today, there is a substance called 2 - Fluoro - 6 - (Trifluoromethyl) Benzenemethanamine. Its shape is also an organic compound with a unique molecular structure. Looking at its structure, the fluorine atom is connected to the benzalkylamine group containing trifluoromethyl, and this unique structure gives it specific chemical properties.
    In the field of chemical research, such compounds are often the focus of attention. Due to the particularity of its structure, it shows extraordinary potential in many fields such as drug development and materials science. Or it can be used as a lead compound to assist in drug creation and act precisely on targets; or it can contribute unique properties in the preparation of new materials. Its chemical activity and reaction characteristics open up a broad space for researchers to explore, waiting for our generation to delve deeper to understand more of its mysteries, so that it can bloom brightly in the path of science.
    Physical & Chemical Properties
    The physicochemical properties of 2-fluoro-6- (trifluoromethyl) aniline are particularly important. Looking at its properties, it may be a colorless to slightly yellow liquid at room temperature, with a special odor. Its boiling point, melting point, etc. are also fixed parameters related to changes in the state of matter. The boiling point or in a specific temperature range, so that the gas-liquid transformation is orderly. The melting point determines the critical between its solid and liquid states.
    In terms of solubility, it may have good solubility in organic solvents such as ethanol and ether, but its solubility in water may be limited. This is due to the presence of fluorine atoms and trifluoromethyl in the molecular structure, which affects the polarity of the molecule, and then affects its interaction with different solvents. The chemical properties of
    , because of its amine group, have certain alkalinity, can neutralize with acid to form corresponding salts. And the conjugate structure of benzene ring makes it able to participate in electrophilic substitution reaction under certain conditions, and may have unique uses in the field of organic synthesis.
    Technical Specifications & Labeling
    Today there is a product called 2 - Fluoro - 6 - (Trifluoromethyl) Benzenemethanamine. In terms of technical specifications and identification (commodity parameters) of the product, our generation should study the school in detail.
    Looking at its structure, the aniline containing fluorine and trifluoromethyl is also. Technical specifications, the first purity, must make the impurities fine before it can be used. The method of synthesis must strictly follow the procedures, and the temperature control and control should not be used. The reaction raw materials, when carefully selected, have excellent texture.
    In terms of identification, the commodity parameters should be detailed. In addition to its name, its molecular weight, melting point, boiling point and other physical constants should also be marked. On the package, it should also be clearly marked to prevent misuse. In this way, the research and development, production, and application of this product can be carried out in an orderly manner without losing accuracy.
    Preparation Method
    To prepare 2 - Fluoro - 6 - (Trifluoromethyl) Benzenemethanamine, the raw materials and production process, reaction steps and catalytic mechanism are crucial.
    First take an appropriate amount of fluoroaromatic hydrocarbons as the starting material, and mix with the reagent containing trifluoromethyl in a specific ratio. In a closed reactor, add a high-efficiency catalyst and adjust the temperature to a suitable range. This is the first step of the reaction. The activity of the catalyst is crucial, which can effectively reduce the activation energy of the reaction and accelerate the reaction process.
    Then, add the aminating reagent dropwise at a specific rate to control the reaction rate and process. During this period, closely monitor the pH and temperature changes of the reaction system and fine-tune it in a timely manner. This step of reaction needs to be precisely controlled to prevent side reactions from breeding.
    After the reaction is completed, it is separated and purified in multiple steps. First, it is preliminarily separated by extraction method, and then further purified by column chromatography to remove impurities, and finally obtain a pure 2-Fluoro-6- (Trifluoromethyl) Benzenemethanamine product. The whole preparation process is closely interlocked, and any deviation may affect the purity and yield of the product.
    Chemical Reactions & Modifications
    In recent years, fluorine substitutes have been studied, including 2-Fluoro-6- (Trifluoromethyl) Benzenemethanamine. Its chemical reaction and modification are important to my research.
    Looking at the way of the past, the reaction of this substance may be difficult to control, and the modification has not been exquisite. However, today's research focuses on the reaction conditions. Choose the right solvent and catalyst to adjust the reaction path, so that the reaction is smooth and the yield is high.
    And think about the way of modification, hoping to use the method of functional group transformation to increase its characteristics. Such as introducing other groups, changing the shape and properties of its molecules, so that more needs can be met. This research has made progress in the field of chemistry, paving the way for various applications, enabling this compound to develop its advantages and meet the needs of the world.
    Synonyms & Product Names
    The name 2 - Fluoro - 6 - (Trifluoromethyl) Benzenemethanamine is synonymous with the name of the commodity, which is related to the research of chemistry and the field of practicality.
    According to the theory of chemistry, this substance has a unique structure. Fluoro (Fluoro) and trifluoromethyl (Trifluoromethyl) belong to the structure of benzenemethanamine, resulting in their unique properties. The synonymous name is named from the chemical structure, characteristics and other aspects, for the convenience of academic communication.
    As for the name of the commodity, or according to its use and characteristics, it is determined by the merchant. In pharmaceutical research and development, it may be a key raw material to assist in the creation of new drugs; in material science, it may also endow materials with special characteristics and increase their functions.
    The synonymous name and trade name of this substance are like a bridge between chemical research and application, enabling researchers to understand its essence and users to know its effectiveness. It has made great contributions to the progress of chemistry and the rise of industry.
    Safety & Operational Standards
    There is a chemical substance today, named 2 - Fluoro - 6 - (Trifluoromethyl) Benzenemethanamine, which is related to its safety and operating standards, and cannot be ignored.
    All handling of this substance is the first priority for the safety of the environment. The place of handling should be well ventilated, and air should not be allowed to float in the room and accumulate and cause trouble. And the place where the object is placed should be kept away from fire and heat sources to prevent accidental fire.
    As for the person who handles it, he should also obey the law. Wear suitable protective clothing, goggles and gloves, and do not let the skin or eyes touch it. If it is accidentally stained on the body, rinse quickly with plenty of water, and then seek medical attention. If it enters the eyes, it must be rinsed immediately, and when rinsing, the eyelids must be fully opened to ensure that the water is washed to the fullest.
    When using this object, use a precise tool and take it according to the quantity. Don't be greedy for too much and leave behind. After using it, store it properly, and the device will also be placed cleanly. When handling, be careful to prevent it from being spilled or damaged.
    If this object is accidentally leaked out, it should be cleared quickly and no one is allowed to approach it. The operator wears professional protective equipment and takes care of it according to regulations. A small amount of leakage can be covered with sand and other objects and put into a special device; if the amount is large, more detailed measures are required to ensure that the environment is clean and everyone is safe.
    In conclusion, although 2 - Fluoro - 6 - (Trifluoromethyl) Benzenemethanamine is useful in chemical exploration, its safety and operation standards must always be kept in mind, and no slack should be allowed to ensure that everything goes well and people are well.
    Application Area
    Today there is a product named 2 - Fluoro - 6 - (Trifluoromethyl) Benzenemethanamine. This product has its uses in various fields.
    In the field of medicine, it can help doctors make good medicines and treat various diseases in the world. Its unique chemical structure can precisely interact with molecules in the body, or can regulate physiological functions, and help remove diseases.
    In materials science, it is also possible. It can help craftsmen create new materials with specific properties, such as better stability, corrosion resistance, etc. Make the utensils durable and beneficial to life and industry.
    Furthermore, in scientific research and exploration, it is the foundation for scholars to develop new theories and innovative methods. Taking it as a guide, it may open up a new way of chemical research, explore the unknown mysteries, and contribute to the advancement of science. This is what 2-Fluoro-6- (Trifluoromethyl) Benzenemethanamine has done, its use is wide and deep, and its contribution in this world cannot be underestimated.
    Research & Development
    In recent years, I studied a thing in my room, called "2 - Fluoro - 6 - (Trifluoromethyl) Benzenemethanamine". This thing has different properties, is related to chemical medicine, and has extraordinary potential.
    I searched day and night to investigate the wonders of its structure and the rules of its reaction. At the beginning, many difficulties lay in front of me, like clouds covering the sun, and it was difficult to see the truth. However, I did not dare to slack off. I consulted ancient classics and visited wise men from all over the world. After countless attempts, I gradually gained the essentials.
    Now I know a little about it, and I know very well that this is an important task of scientific research. I will do my best to continue to study and expand the field of its application, hoping to contribute to the academic community and industry, and help it thrive.
    Toxicity Research
    Since modern times, chemical refinement has produced all kinds of new products. Today there is a product named "2-Fluoro-6- (Trifluoromethyl) Benzenemethanamine", and our generation focuses on its toxicity.
    Looking at this substance, it has a unique structure and contains groups of fluorine and trifluoromethyl. Such groups have been found to be involved in toxic changes in the past. Fluoride is active, easy to react with other substances, or cause cell biochemistry. Trifluoromethyl has strong electron absorption, or changes the physicochemical properties of molecules, increases its fat solubility, promotes its entry into biofilms, and then disturbs the function of cells.
    To understand its toxicity, it must be applied in combination with multiple methods. Looking at its shadow on cells, we can measure the proliferation and apoptosis of cells; taking animals as models, we can study its entry into the body to observe the damage of organs and physiological changes. And the degradation and fate of this substance in the environment are also related to ecological security. Only by studying it in detail can we know the mystery of its toxicity. For protection and application, it is the right way to avoid harm and seek profit, and ensure the well-being of all beings and the tranquility of the environment.
    Future Prospects
    The future prospects of 2 - Fluoro - 6 - (Trifluoromethyl) Benzenemethanamine are crucial for this chemical. Although its basic characteristics are now known, there are still many things to be explored in the future.
    To achieve a wider application of this chemical, it is necessary to study the synthesis process. Optimize the process, reduce its cost, and increase its purity to make large-scale production possible. In this way, in the field of medicine, it may lay the foundation for the development of new drugs to cure more difficult diseases; in material science, it may give birth to novel materials with unique physical and chemical properties.
    Furthermore, in-depth investigation of its reaction mechanism, to clarify the law of its interaction with other substances, can expand the boundaries of application. Or emerge in the field of catalysis, or add to the fine chemical industry. In the future, with unremitting research, we should unlock the unlimited potential of this chemical and make it contribute extraordinary power to human well-being.
    Where to Buy 2-​Fluoro-​6-​(Trifluoromethyl)​Benzenemethanamine in China?
    As a trusted 2-​Fluoro-​6-​(Trifluoromethyl)​Benzenemethanamine manufacturer, we deliver: Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements. Technical Excellence: Precision-engineered solutions backed by R&D expertise, from formulation to end-to-end delivery. Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.
    Frequently Asked Questions

    As a leading 2-​Fluoro-​6-​(Trifluoromethyl)​Benzenemethanamine supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

    What are the main uses of 2-fluoro-6- (trifluoromethyl) aniline?
    2-% alkene-6- (trienomethyl) benzylpyridine is one of the valuable organic compounds. Its main uses are widely used in many fields such as medicine and materials science.
    In the field of medicine, this compound is often used as a key intermediate. Due to its unique chemical structure, different functional groups can be introduced by organic synthesis to build more complex and diverse drug molecules. For example, for specific disease targets, through rational drug design, 2-% ene-6- (trienomethyl) benzylpyridine can be used as a starting material to synthesize drugs with precise pharmacological activity, or for the development of anti-tumor drugs, through which it interacts with specific proteins or signaling pathways in tumor cells to inhibit the proliferation and spread of tumor cells; or for the creation of drugs for neurological diseases, to help regulate the transmission of neurotransmitters and improve related diseases.
    In the field of materials science, 2-% ene-6- (trienomethyl) benzylpyridine also plays an important role. Due to its special physical and chemical properties endowed by its structure, it can be applied to the preparation of new functional materials. For example, in the field of photoelectric materials, with appropriate modification and processing, the materials based on this can exhibit excellent photoelectric conversion performance, which is expected to be used to manufacture high-efficiency organic solar cells and improve the conversion efficiency of solar energy; or for the preparation of luminescent materials, applied to organic Light Emitting Diode (OLED) technology to improve the luminescence and color performance of display devices.
    In addition, in the field of catalysis, 2-% ene-6- (trienyl methyl) benzylpyridine can be used as a ligand to coordinate with metal ions to form a complex catalyst. With its unique spatial structure and electronic effect, this catalyst exhibits high selectivity and catalytic activity for specific chemical reactions, promoting the efficient progress of chemical reactions, and has potential application value in the industrial production of organic synthetic chemistry.
    What are the physical properties of 2-fluoro-6- (trifluoromethyl) aniline?
    2-% Jiang-6- (triethylmethyl) phenethylpyridine, this is a rather special organic compound with unique physical properties.
    Looking at its appearance, under room temperature and pressure, it is mostly a colorless to light yellow transparent liquid, with a clear texture, like a clear spring. Under the light, it may have a faint luster, just like a little bit of starlight hidden in the liquid.
    When it comes to smell, it exudes a special aromatic smell. This smell is neither rich and pungent, nor elegant and hard-to-find fragrance, but has a unique charm, slightly fragrant, and mixed with a little unique smell of organic compounds, just like a unique fragrance that combines natural and artificial carving.
    The boiling point and melting point are also important physical properties. Its boiling point is within a specific range, and it needs to reach a certain temperature to change from liquid to gaseous due to intermolecular forces. The exact value of this temperature is determined by its molecular structure and intermolecular interactions, reflecting the energy required for molecules to break free from each other. In terms of melting point, when the temperature drops to a certain value, the substance will solidify from liquid to solid, forming a regular lattice structure. This process is accompanied by the release of heat. The melting point value is of great significance in defining the physical state transition conditions of the substance. In terms of solubility, it exhibits good solubility in organic solvents, such as common ethanol, ether and other organic solvents, which can be fused with it, just like fish water, forming a uniform and stable solution. This property is due to the interaction between its molecular structure and organic solvent molecules, such as van der Waals force, hydrogen bonding, etc., which allows the molecules to be uniformly dispersed in the solvent. However, in water, its solubility is quite limited. Due to the large difference between the polarity of water and the molecular polarity of the compound, the two are difficult to dissolve each other, just like oil and water. Density is also a physical property that cannot be ignored. Compared with water, its density may be different. By virtue of this property, it can be separated from other liquids according to the density difference in operations such as liquid-liquid separation, providing convenience for its application in chemical industry, scientific research and other fields.
    Is the chemical properties of 2-fluoro-6- (trifluoromethyl) aniline stable?
    Are the chemical properties of 2-meta-6- (trimeta-methyl) benzylpyridine stable? To understand this, it is necessary to investigate its structure and reactivity in detail.
    Looking at its structure, 2-meta-6- (trimeta-methyl) benzylpyridine contains aromatic rings, pyridine rings and specific substituents. The aromatic ring has a conjugated system, which makes it have certain stability and electron delocalization. The nitrogen atom in the pyridine has lone pair electrons, which affects the distribution of molecular electron clouds and reactivity. The existence of trimeta-methyl alters the molecular spatial resistance and electronic effects.
    In chemical reactions, the stability of this compound is affected by many factors. From the theory of electronic effects, tri-methyl can increase the electron cloud density of aromatic ring and pyridine ring, making electrophilic substitution reaction easy to occur, but it may also affect the stability of oxidation and reduction reactions due to the change of electron cloud density. In terms of spatial location, tri-methyl is large in volume, or prevents the reactants from approaching the active check point, slowing down the reaction rate in some reactions, but protecting specific parts of the molecule to a certain extent and improving stability.
    Considering its environment, 2-tri-6- (tri-methyl) benzylpyridine is relatively stable under normal temperature and pressure and no special reagents. However, under extreme conditions such as strong acid, strong base, strong oxidant or high temperature and high pressure, its chemical bonds may be destroyed, and hydrolysis, oxidation, ring opening and other reactions occur, resulting in a sudden drop in stability.
    In summary, the stability of 2-dip-6- (tridip methyl) benzylpyridine is not absolute, but varies according to specific conditions. It is relatively stable under mild conditions, but its stability may vary significantly in special chemical environments and reaction conditions.
    What are the synthesis methods of 2-fluoro-6- (trifluoromethyl) aniline?
    To prepare 2-alkynyl-6- (triethylmethyl) naphthalene ethane, there are various methods, which are described in detail as follows:
    First, it can be replaced by nucleophilic substitution. First, a halogen-containing naphthalene ethane derivative is prepared. If a suitable naphthalene is used as the starting material, through a halogenation reaction, a halogen atom is introduced into a specific position of the naphthalene ring to form a halogenated naphthalene ethane. Another triethylmethyl reagent, such as the corresponding organometallic reagent, is common such as Grignard reagent or lithium reagent. This reagent has strong nucleophilic properties. When it encounters the halogenated naphthalene ethane, the halogen atom leaves, and the nucleophilic reagent attacks the carbon position where the carbon-halogen bond is In this process, attention should be paid to the control of reaction conditions, such as reaction temperature and solvent selection. At low temperature, the reaction may be slow, but it can reduce side reactions; although high temperature increases, it may cause side reactions to cluster. Aprotic solvents, such as tetrahydrofuran, are often suitable for nucleophilic substitution, because they have good solubility to nucleophilic reagents and do not react with reagents, which can help the reaction proceed smoothly.
    Second, the coupling reaction of alkynes can be used. First, the naphthalene ethane containing alkynyl group is prepared, and the halogenated hydrocarbon containing triethyl methyl group is coupled in the presence of suitable catalysts, ligands and bases. Commonly used catalysts such as palladium catalysts, ligands such as phosphine ligands, and bases such as potassium carbonate. In the reaction mechanism, palladium catalysts are first oxidized and added to halogenated hydrocarbons to form active intermediates. Alkynes are then coordinated with intermediates, migrated and inserted, and finally eliminated by reduction to form carbon-carbon bonds to obtain the target product. This reaction requires quite high requirements for catalysts and ligands. Different combinations of catalysts and ligands have a great impact on reaction activity and selectivity. And the reaction system needs to be anhydrous and oxygen-free to prevent catalyst deactivation.
    Third, it can be prepared by the addition reaction of alkynes and alkenes. Naphthalene ethane containing alkenyl groups and corresponding alkynes derivatives are first synthesized. Under the action of suitable catalysts, such as transition metal catalysts, alkynes and alkenes undergo addition reactions. This process involves complex catalytic cycles. The catalyst is first coordinated with alkynes or olefins, and through a series of migration and insertion, rearrangement and other steps, new carbon-carbon bonds are formed to build the skeleton of the target molecule. Fine regulation of reaction conditions is crucial, and factors such as temperature and pressure all affect the reaction process and product selectivity.
    The above methods have their own advantages and disadvantages. In actual synthesis, it is necessary to weigh and choose according to factors such as the availability of raw materials, the feasibility of reaction conditions, and the purity requirements of the product.
    What is the price range of 2-fluoro-6- (trifluoromethyl) aniline in the market?
    The price range of 2-% Jiang-6- (trimethyl) -naphthoic acid in the market is difficult to determine. This is due to the ever-changing market conditions, and its price often fluctuates with various factors.
    Looking at the supply and demand of raw materials, if the raw materials are abundant, the price may stabilize or even decrease; on the contrary, if the raw materials are scarce, the demand is too high, and the price will rise. And the progress of the process also has an impact. If new technologies are released, the production efficiency will increase and the cost will decrease, and the price may change accordingly. Furthermore, the demand of the market is also the key. If this product is needed by the public industry at a certain time, the price will increase if it is prosperous; if there is no great demand, the price will be difficult to increase.
    In addition, political regulations, tax adjustments, etc. can all affect its price. Therefore, if you want to determine the price range, you must often look at the market conditions and analyze them based on current information. For now, it is difficult to determine an exact price range, but only by closely observing the dynamics of the market can you obtain a near-real price.