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2-Fluoro-5-(Trifluoromethyl)Benzenesulphonyl Chloride

2-Fluoro-5-(Trifluoromethyl)Benzenesulphonyl Chloride

Hongda Chemical

    Specifications

    HS Code

    368136

    Chemical Formula C7H3ClF4O2S
    Molecular Weight 262.61
    Appearance Typically a colorless to pale yellow liquid
    Boiling Point Data may vary, but around a certain temperature range depending on purity
    Melting Point Specific melting point value relevant to its physical state transition
    Density Characteristic density value for the compound
    Solubility Solubility characteristics in common solvents like organic solvents
    Purity Typical purity levels achievable or commercially available
    Vapor Pressure Vapor pressure data indicating volatility
    Stability Information on its chemical stability under normal and specific conditions

    As an accredited 2-Fluoro-5-(Trifluoromethyl)Benzenesulphonyl Chloride factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing 100g of 2 - fluoro - 5 - (trifluoromethyl)benzenesulphonyl chloride in a sealed glass bottle.
    Storage 2 - fluoro - 5 - (trifluoromethyl)benzenesulphonyl chloride should be stored in a cool, dry, well - ventilated area. It must be kept away from heat, flames, and moisture as it is reactive. Store it in a tightly sealed container, preferably made of corrosion - resistant materials. Segregate it from incompatible substances like bases, reducing agents, and water - reactive compounds to prevent dangerous reactions.
    Shipping 2 - fluoro - 5 - (trifluoromethyl)benzenesulphonyl chloride is a chemical. It should be shipped in well - sealed, corrosion - resistant containers, following strict hazardous material shipping regulations to ensure safety during transit.
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    2-Fluoro-5-(Trifluoromethyl)Benzenesulphonyl Chloride 2-Fluoro-5-(Trifluoromethyl)Benzenesulphonyl Chloride
    General Information
    Historical Development
    2-Fluoro-5- (trifluoromethyl) benzenesulfonyl chloride is also a genus of chemical substances. Tracing back to its source, at the beginning, people explored in the field of chemistry, and studied various compounds more and more deeply. At that time, science and technology were not as developed as they are today, and although the research progress was slow, many people made unremitting efforts. After years of experiments, observations and analysis, the relevant knowledge of this compound has been obtained. With the passage of time, science and technology have gradually developed, and the experimental methods have become more refined. The properties and preparation methods of 2-fluoro-5- (trifluoromethyl) benzenesulfonyl chloride are understood more and more. The hardships of past exploration have become the cornerstone of today's cognition. The use of this compound in chemical, pharmaceutical and other fields has gradually become apparent, paving the way for subsequent chemical research. This has led countless researchers to continue to explore its mysteries in the chemical hall, making its development prospects increasingly broad.
    Product Overview
    Today there is a substance called 2-fluoro-5- (trifluoromethyl) benzenesulfonyl chloride. It is a key substance in chemical research and has a wide range of uses in the field of scientific research. This substance has unique properties, pure color and uniform quality, and provides a precise basis for scientific research experiments.
    Its delicate structure, fluorine is cleverly connected with trifluoromethyl and benzenesulfonyl chloride, resulting in its active chemical properties and unique reactivity. In the process of organic synthesis, it is often used as a key reagent, which can introduce special groups into organic molecules and help create new compounds.
    To study this substance, it is necessary to study its reaction mechanism carefully and understand the laws of its interaction with other substances in order to exert its maximum effectiveness in scientific research and application, and to contribute to the progress of chemical research, to explore new frontiers, and to open new chapters.
    Physical & Chemical Properties
    Since 2024, the international situation has been complex and changeable, and in the economic field, countries have faced different challenges and opportunities. 2 - Fluoro - 5 - (Trifluoromethyl) Benzenesulphonyl Chloride This compound is particularly important in terms of physical and chemical properties. Looking at its physical properties, at room temperature, it mostly takes a specific form, or is a solid state, with a specific color and appearance. Its melting point and boiling point can be found in relevant ancient books or experimental records, which are related to its state changes under different temperature conditions. As for its chemical properties, the arrangement and combination of atoms in its molecular structure give it unique reactivity. In a specific chemical reaction environment, or with a certain type of reagent substitution reaction, or to participate in the addition of change, the reaction conditions such as temperature, catalyst requirements, are all rules to follow, exploring the physical and chemical properties of this compound can lay a solid foundation for its application in chemical, pharmaceutical and other fields, and also pave the way for further research.
    Technical Specifications & Labeling
    2-Fluoro-5- (trifluoromethyl) benzenesulfonyl chloride is an important chemical product. Its technical specifications and identification (product parameters) are crucial. The quality of this product is related to the purity of the raw materials used, and the process must be accurate. In the technical specifications, the proportion of ingredients should be in accordance with specific regulations, and the impurity content must be strictly controlled at an extremely low level. Above the label, the name, chemical formula 2-Fluoro-5- (Trifluoromethyl) Benzenesulphonyl Chloride should be clear, and warning words should be marked to inform its properties, such as corrosion, toxicity, etc. It should also be indicated. It should be placed in a dry place to avoid heat and fire. In this way, we can ensure the quality of this product and the safety of users, and make every effort in the chemical industry.
    Preparation Method
    To prepare 2-fluoro-5- (trifluoromethyl) benzenesulfonyl chloride, first take fluorobenzene and trifluoromethylation reagent, according to a certain ratio, in a special container, temperature-controlled heating, so that the two combine according to a specific reaction mechanism to form a fluorobenzene derivative containing trifluoromethyl.
    Then, the derivative and the sulfonation reagent are co-placed in a reactor, adjusted to a suitable pH and temperature, and then sulfonated to introduce the benzene ring into the sulfonic acid group.
    Then take thionyl chloride as a chlorination reagent, mix it with the above product, react under specific conditions, transform the sulfonic acid group into a sulfonyl chloride group, and then obtain 2-fluoro-5- (trifluoromethyl) benzenesulfonyl chloride. The whole process requires precise control of raw material dosage, reaction temperature and time to ensure product purity and yield.
    Chemical Reactions & Modifications
    The reaction and modification of 2 - Fluoro - 5 - (Trifluoromethyl) Benzenesulphonyl Chloride is a key task in chemical research. The mechanism of the reaction is related to the structure and bonding of molecules. The interaction between molecules, whether nucleophilic or electrophilic, all cause the transformation of this compound under specific conditions.
    To seek its modification, many factors should be considered. Such as temperature and solvent, can affect the rate and direction of the reaction. Choosing the right temperature can make the reaction smooth and obtain the expected product. The properties of the solvent, whether polar or non-polar, also have special effects on the stability of the intermediate.
    Furthermore, the addition of catalysts can often change the activation energy of the reaction, so that the reaction can be accelerated. In the research of 2-Fluoro-5- (Trifluoromethyl) Benzenesulphonyl Chloride, the insight into the reaction and modification can pave the way for its practical application, so that it can develop its talents in chemical and pharmaceutical fields.
    Synonyms & Product Names
    I have heard that there is a thing named 2 - Fluoro - 5 - (Trifluoromethyl) Benzenesulphonyl Chloride. Although its name is complex, it is very important in my way of chemistry.
    Such substances may have other names, or they may have the same name. In the industry, all kinds of trade names are different according to their own, and they are called differently. Such as merchants trading, they are often remembered by different names, which is the so-called trade name.
    The same name is also covered, or due to differences in regions, or due to differences in practice. However, its essence is this thing. Those of us who study should scrutinize the differences and distinguish the name changes of the same thing, so that we can study chemistry without confusion and travel freely. In all kinds of literature, careful screening can be used to understand the difference between the names of this thing and the truth.
    Safety & Operational Standards
    2-Fluoro-5- (trifluoromethyl) benzenesulfonyl chloride, this chemical substance is related to safety and operating standards, and is extremely important. It should be discussed in detail.
    This product is also strong and sensitive. When operating, it is the first priority to ensure the safety of the environment. It must be placed in a well-ventilated place to prevent the accumulation of turbid gas. The utensils used must be clean and airtight to prevent leakage.
    As far as the operator is concerned, protective gear is indispensable. Wear special protective clothing to prevent its corrosion; wear anti-corrosion gloves on your hands to avoid skin contact; cover your face with goggles to ensure the safety of your eyes. And when operating, the mind must be focused and not slack.
    As for storage, it is advisable to choose a cool and dry place, away from fire and heat sources. Do not store with easily reactive objects to prevent accidents. When taking it, use it with accurate measures, follow the prescribed methods, and do not exceed the norm.
    If there is a leak, quickly cut off the root cause, and it is strictly forbidden for the fire to approach. Small leaks can be adsorbed with sand and other objects, and properly collected and disposed of; when there is a big leak, everyone should quickly leave, set up warning signs, and call professional people to solve the crisis.
    In conclusion, the safety and operating standards of 2-fluoro-5- (trifluoromethyl) benzenesulfonyl chloride are essential to ensure personal and environmental safety. They must not be taken lightly and must be strictly followed in order to remain safe.
    Application Area
    Today there is a product called 2 - Fluoro - 5 - (Trifluoromethyl) Benzenesulphonyl Chloride, which is available in various fields. In the genus of medicine, it can be used as a raw material for the synthesis of pharmaceuticals, helping to create new agents and cure various diseases. In the field of materials, it can be used as a modification aid to make the material specific, such as enhancing corrosion and wear resistance. In chemical synthesis, it is often used as a key reagent to build complex molecular structures and expand the variety of chemical products. Its wide application is like a starry sky, and it is of great significance in the development of many industries. It is also an indispensable chemical product.
    Research & Development
    In recent years, I have been studying chemical substances, especially 2 - Fluoro - 5 - (Trifluoromethyl) Benzenesulphonyl Chloride. Its unique nature often plays a key role in various chemical reactions.
    I began to explore the method of its preparation. After many attempts, I reconciled the materials, controlled their temperature, pressure and timing, and strived for delicacy. At the beginning, the results were not obvious, but I was not discouraged. I carefully observed the changes in each step to study the gains and losses.
    After a long trial, I gradually obtained the best method, and the yield gradually increased. When this product was made, I studied its application and tried it in various fields of medicine and materials, hoping to develop its growth and expand its use. Looking at the harmony between it and other things, it generates new materials and has new energy, which is expected to add new strength to various industries.
    In the future, when following up on this product, refining its preparation, and expanding its application, it is expected to be in the field of chemistry, making pioneering achievements and promoting its industry progress.
    Toxicity Research
    In modern times, the art of studying poison has gradually refined. In 2 - Fluoro - 5 - (Trifluoromethyl) Benzenesulphonyl Chloride, everyone pays attention to its toxicity. I study it carefully and investigate its properties in detail.
    The color state of this thing is first seen, or it is a clear liquid, or it is a fine microcrystalline end, but although its appearance is flat, it is highly toxic. Try all kinds of things that are effective, and insects touch it, and it will freeze in an instant; birds smell it, and it will die soon.
    Investigate its toxicology, and when it enters the body, it will disrupt qi and blood, and damage the internal organs. Those who have internal organs are the foundation of human beings, and those who have qi and blood are the protection of the body. Under this poison, the functions of the internal organs are methodical, and the qi and blood run obediently. The light ones are tired and tired, and the lives of the heavy ones are worried.
    The prevention of poison, the first heavy equipment is strictly sealed, so as not to leak; the second is that those who handle it must wear protective equipment, be cautious, and not slack in the slightest. Although it is a poison research, it is intended to clarify its nature, avoid its harm, and ensure the safety of all living beings.
    Future Prospects
    I have tried to study chemical things, and today I am talking about 2 - Fluoro - 5 - (Trifluoromethyl) Benzenesulphonyl Chloride. It is unique in nature and has great potential in various fields of chemical industry. Although it is not widely used today, looking at its characteristics, it seems to be able to emerge in the creation of medicine. Or it can be used as a medicine for new diseases to heal old diseases; or it can be used for material innovation and new energy. In the future, we can expect it to bridge and pave the way between scientific research and industry, so that our generation can explore nature and benefit the world more smoothly. In time, it will surely be like a star shining in the sky, shining brightly, and will be used by future generations, benefiting all nations.
    Where to Buy 2-Fluoro-5-(Trifluoromethyl)Benzenesulphonyl Chloride in China?
    As a trusted 2-Fluoro-5-(Trifluoromethyl)Benzenesulphonyl Chloride manufacturer, we deliver: Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements. Technical Excellence: Precision-engineered solutions backed by R&D expertise, from formulation to end-to-end delivery. Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.
    Frequently Asked Questions

    As a leading 2-Fluoro-5-(Trifluoromethyl)Benzenesulphonyl Chloride supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

    What are the physical properties of 2-fluoro-5- (trifluoromethyl) benzenesulfonyl chloride?
    In terms of solubility, it has a certain solubility in water, and can form a homogeneous dispersion system. This is because its molecules contain water-based molecules, and water molecules can form specific interactions. In the soluble solution, such as ethanol, acetone, etc., there are also different degrees of dissolution, which depend on the degree of matching of the molecular force.
    Its density is fixed, and under normal conditions, the obtained value can be tested, reflecting the resistance of its position. In addition, 2-% Jiang-5- (trimethyl) indolesulfonic acid has a certain sensitivity to light. Under light, the molecules are modified or altered, resulting in some changes in color, chemical activity, etc.; subject to a certain boundary, it will cause decomposition, rearrangement, etc., so it is necessary to pay attention to avoid light and control when using it. Its acidity in the solution is also exquisite, which can weakly affect the activity of its existence form, which is due to its important physical properties. It is essential for the application of the phase domain.
    What are the chemical properties of 2-fluoro-5- (trifluoromethyl) benzenesulfonyl chloride?
    2-% Jiang-5- (Sanjiang methyl) benzothiazole formaldehyde, this physical property is special, with the general nature of organic aldehyde. Its aldehyde group is active and can participate in many reactions.
    Nucleophilic addition, aldehyde carbons show positive electrical properties, easy to attack by nucleophilic reagents. Such as with alcohols, under the catalysis of acid, into semi-acetal, and then into acetal. This acetal is stable in alkali, acidic hydrolysis and complex into aldehyde, often used as a method of carbonyl protection. Polyfunctional groups such as cyanic acid, cyanogenic alcohol, cyano-transferable carboxyl groups, amine groups, etc., are essential for organic synthesis.
    Oxidation reaction, can be oxidized by weak oxidants such as Torun reagent to form carboxylate, now silver mirror, this reaction can identify aldehyde groups. In case of strong oxidants such as potassium permanganate, aldehyde groups form carboxylic groups, and if benzene rings have easily oxidized substituents, they may also be oxidized.
    Reduction reaction, with lithium aluminum hydride, sodium borohydride, etc., aldehyde groups can form alcohol hydroxyl groups to obtain benzothiazole methanol.
    Condensation reaction, aldehyde groups α-hydrogen have activity, can be condensed with hydroxyaldehyde containing α-hydroaldehyde and ketones under alkali catalysis, and the carbonization chain can produce α, β-unsaturated aldosteroids and ketones, which are widely used in organic synthesis. It can also be condensed with ammonia derivatives such as hydroxylamine, hydrazine, etc., oxime, hydrazone, and more have specific colors and melting points, which can identify and purify the substance.
    It has a benzothiazole ring and is aromatic. It can be referred to electrophilic substitution reactions, such as halogenation, nitrification, sulfonation, etc. The electron cloud density distribution of benzothiazole ring is different from that of benzene, and the substitution check point is different. Generally, electrophilic reagents attack areas with high electron cloud density.
    In summary, 2-% Jiang-5- (Sanjiang methyl) benzothiazole formaldehyde coexists with benzothiazole ring, and the reaction is rich. It has potential applications in organic synthesis, medicinal chemistry, materials science and other fields.
    What are the common uses of 2-fluoro-5- (trifluoromethyl) benzenesulfonyl chloride?
    The common use of 2-% Jiang-5- (triethylmethyl) benzothiazolinone hydrazone is for the detection of aldehyde substances in solution. It plays a great role in the field of analytical chemistry.
    When this reagent meets aldose, it will have a specific chemical reaction and produce products with a specific color. By observing the color change, the existence of aldose can be determined. According to the color depth, the content of aldehyde can be accurately determined by spectrophotometry and other means.
    In terms of water quality monitoring, it can detect aldehyde pollutants in water, such as formaldehyde, which are harmful to the human body. Formaldehyde is common in industrial wastewater and volatiles of interior decoration materials. If the content in water exceeds the standard, it is harmful to the environment and human body. Detection with 2-% Jiang-5- (triethylmethyl) benzothiazolinone hydrazone can help control water quality safety.
    In the field of food testing, it can detect aldose substances in food. Some foods will generate aldose during processing and storage, such as malondialdehyde produced by oil oxidation. Detecting its content can know the freshness and quality of food, and ensure food safety.
    In biochemical research, it also has important uses. Certain metabolic processes in organisms generate aldose, through which the detection of reagents can gain insight into metabolic changes in organisms, and help study the mechanism of disease occurrence and the principle of drug action.
    In summary, 2-% Jiang-5- (triethylmethyl) benzothiazolinone hydrazone plays a key role in the detection of aldehyde in many fields due to its specific reaction with aldehyde, which is of great significance for the development of environmental protection, food and life science research.
    What is the synthesis method of 2-fluoro-5- (trifluoromethyl) benzenesulfonyl chloride?
    To prepare 2-Ming- 5- (trimingmethyl) phenylselenaldehyde, the following ancient method can be used.
    First take an appropriate amount of raw materials, and select those with pure texture. Take the benzene derivative as the starting material, and add an appropriate amount of reagent to a specific reactor. This reagent needs to be prepared in an appropriate proportion. Taking trimingmethyl halide as an example, the molar ratio of it to the benzene derivative should be a certain value. This value needs to be accurately determined by many tests according to the specific situation of the reaction.
    Then, add a specific catalyst, which has a great impact on the reaction rate and product selectivity. Commonly used catalysts, such as certain types of metal salts or organometallic complexes, also need to be strictly controlled in the amount added.
    When reacting, the temperature and pressure need to be precisely regulated. The temperature should be maintained in a certain range, such as between [X1] ° C and [X2] ° C, and the pressure should be stable at about [P] atmospheric pressure. If the temperature is too high, it is feared that side reactions will increase and the product will be impure; if the temperature is too low, the reaction rate will be slow and take a long time.
    During the reaction process, it is necessary to continuously stir to make the reactants fully mixed and contacted to promote the uniform progress of the reaction. When the reaction reaches the expected level, the appropriate separation and purification method can be selected according to the characteristics of the product. If the boiling point of the product and the reaction mixture is significantly different, distillation can be used; if the solubility of the product in a specific solvent is different, extraction can be used.
    After a series of separation and purification operations, a relatively pure 2-Ming- 5 - (triMingmethyl) phenylselenaldehyde can be obtained. However, in this process, each step of the operation needs to be fine, and a slight difference may affect the yield and purity of the product.
    What are the precautions for storing and transporting 2-fluoro-5- (trifluoromethyl) benzenesulfonyl chloride?
    There are three things to pay attention to when storing 2-% Jiang-5- (Sanjiang methyl) naphthalene cyanane oil. First, this oil is volatile, and if it is not stored properly, it is easy to reduce its quality loss. Therefore, it should be placed in a cool and closed place, away from direct sunlight and hot topics, so as to keep its stability and avoid the risk of volatilization. Second, this oil is flammable in the event of an open flame, and the place where it is stored is strictly prohibited from fireworks, and there should be no things that are prone to static electricity. The reservoir must be grounded to conduct static electricity to prevent static electricity from igniting and causing unexpected disasters. Third, when handling, be careful. This oil is mostly glass or special containers, which are brittle and easy to break. If the handling is reckless, causing the oil to break and leak, it will not only damage the goods, but also cause the risk of slipping in the oily land. If the oil flows into the waterway, it will also pollute the environment. In addition, the person handling should wear protective equipment to prevent oil from touching the body and hurting the skin. All of these are the essentials for the storage and delivery of 2-% Jiang-5- (Sanjiang methyl) naphthalene cyanane oil, and should not be ignored. Only by following these items can we ensure the safety of storage and transportation and avoid all kinds of disasters.