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2-Fluoro-5-Bromonitrobenzene

2-Fluoro-5-Bromonitrobenzene

Hongda Chemical

Specifications

HS Code

685667

Chemical Formula C6H3BrFNO2
Molar Mass 236.00 g/mol
Appearance Solid
Color Yellow to light brown
Melting Point 43 - 47 °C
Boiling Point 239 - 240 °C
Density 1.869 g/cm³
Solubility In Water Insoluble
Solubility In Organic Solvents Soluble in common organic solvents like dichloromethane, chloroform
Flash Point 102.5 °C

As an accredited 2-Fluoro-5-Bromonitrobenzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

Packing & Storage
Packing 250g of 2 - fluoro - 5 - bromonitrobenzene packaged in a sealed glass bottle.
Storage 2 - fluoro - 5 - bromonitrobenzene should be stored in a cool, dry, well - ventilated area. Keep it away from heat sources, open flames, and incompatible substances such as strong oxidizing agents. Store in a tightly closed container to prevent leakage and exposure to air or moisture. This helps maintain its stability and reduces the risk of hazardous reactions.
Shipping 2 - fluoro - 5 - bromonitrobenzene is shipped in tightly sealed, corrosion - resistant containers. It follows strict hazardous chemical shipping regulations, ensuring proper labeling and secure handling during transit to prevent spills and ensure safety.
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2-Fluoro-5-Bromonitrobenzene 2-Fluoro-5-Bromonitrobenzene
General Information
Historical Development
Those who have heard of ancient chemistry have explored the properties and changes of matter, and have made unremitting research, so many wonderful achievements have come out. In today's words, 2 - Fluoro - 5 - Brocamerrobenzene is becoming increasingly important in the field of chemistry.
In the past, chemistry was at its dawn, but everyone's exploration in the microscopic world was still shallow. With the passage of time and the advance of science and technology, researchers have a deeper understanding of organic compounds. The discovery of 2 - Fluoro - 5 - Brocamerrobenzene is an important node in the development of chemistry. In the early days, scholars began to understand its structure and properties through countless experiments and analyses. Since then, many chemists have conducted research on it, exploring methods for synthesis, optimizing the process, and making it a treasure in the laboratory. It can be gradually prepared on a large scale and applied to medicine, materials, and many other fields to promote the development of the chemical industry. It is a key substance in the evolution of chemical history, witnessing the progress and brilliance of chemistry.
Product Overview
Today there is a compound called 2 - Fluoro - 5 - Brocamerrobenzene. It is an organic compound with a unique structure. Looking at its molecules, fluorine atoms, bromine atoms and nitro groups are co-attached to the benzene ring. This compound is used in the field of organic synthesis and has a wide range of uses.
can be used as an intermediate to create a variety of drugs, pesticides and fine chemicals. Its characteristics of fluorine, bromine and nitro give it unique chemical activity. The fluorine atom makes the molecule highly stable and fat-soluble; the bromine atom can enhance the reactivity and facilitate derivatization; the nitro group facilitates the introduction of other functional groups. The
preparation method often goes through a multi-step reaction, and the reaction conditions are carefully adjusted according to the mechanism of benzene ring substitution reaction to achieve higher yield and purity. This substance is an important raw material in chemical research and development, laying the foundation for innovation and development in many fields.
Physical & Chemical Properties
2 - Fluoro - 5 - Brocamerrobenzene is an important raw material for organic synthesis, and its physical and chemical properties are of great research value. This compound is in a light yellow crystalline shape, with a melting point of about [X] ° C, and is stable at room temperature and pressure.
Its chemical properties are active, and fluorine atoms, bromine atoms and nitro groups give it unique reactivity. Nitro has strong electron absorption, which reduces the electron cloud density of the benzene ring, which is conducive to nucleophilic substitution reactions. Bromine atoms and fluorine atoms can participate in common reactions of halogenated hydrocarbons, such as nucleophilic substitution, metal catalytic coupling, etc.
It has good solubility in organic solvents, such as dichloromethane, N, N - dimethylformamide, which is easy to operate. Under specific conditions, it can be chemically converted to generate a variety of derivatives for use in medicine, pesticides and other fields. In-depth exploration of their physicochemical properties will provide a solid foundation for applications in related fields.
Technical Specifications & Labeling
Today there is a thing, the name is 2 - Fluoro - 5 - Brocamerrobenzene. The method of its production is related to technical specifications and identification (product parameters), which is of paramount importance.
To make this thing, it is necessary to specify the amount of materials used, and each thing is mixed according to a certain rule. In a suitable device, control its temperature and time, so that the things are changed. If the materials are combined in a kettle, boil them slowly, observe their changes, and observe their degree to obtain good quality.
Its identification (product parameters) also needs to be detailed. The color should be pure, no variegated color; the taste should be correct, no peculiar smell. The number of its quality must be in line with the regulations, such as the purity geometry and the number of impurities, all of which should be confirmed. In this way, the qualified 2-Fluoro-5-Brocamerrobenzene can be used in all required places, and in the field of chemical industry, it can be used to the best of its ability.
Preparation Method
The method of making 2 - Fluoro - 5 - Brocamerrobenzene is the first raw material and production process. The raw material should be selected when it is pure and easy to obtain. If fluorobenzene is used as the base, supplemented by brominating agent and nitrifying agent, this is the common way.
Its production process, the reaction step is the key. First, the fluorobenzene and the brominating agent should be combined at a specific temperature and time to obtain bromofluorobenzene. Next, the nitrifying agent is added, the temperature is controlled and the speed is adjusted, and the nitrification is made to obtain the target product.
Furthermore, the catalytic mechanism cannot be ignored. Selecting the appropriate catalyst can promote the reaction rate and improve the product rate. For example, a certain type of metal salt catalyst can reduce the activation energy between reactions and make the reaction easy to progress. In this way, through careful selection of raw materials, exquisite process operation, and appropriate catalytic regulation, high-quality 2-Fluoro-5-Brocamerrobenzene can be obtained.
Chemical Reactions & Modifications
Today there is a chemical substance, named 2 - Fluoro - 5 - Brocamerrobenzene. In the field of chemistry, its reaction and modification are crucial. This compound, because of its unique structure, exhibits special properties in various reactions.
Looking at its reaction, it can be combined with various reagents, substitution, addition and other changes. To change its properties, you can use chemical means, such as changing its group, adjusting its environment, and making beneficial changes. For example, by using specific methods, the position of fluorine, bromine, or the state of nitro can be changed, which can make the product have different properties and is very useful in medicine and materials.
Chemists study the reaction and modification of this substance, hoping to expand its path, increase its efficiency, benefit people's livelihood, and promote the progress of science and technology. Unremitting exploration, in the field of chemistry, to get more subtle methods, so that 2 - Fluoro - 5 - Brocamerrobenzene and its derivatives can be used by the world and add luster to the chemical industry.
Synonyms & Product Names
2 - Fluoro - 5 - Brocamerrobenzene, the synonym and trade name of this substance, is of great research value. Its synonyms are different expressions of the substance in scientific exploration, each with its origin and application scenarios. The trade name is related to commercial circulation and market identification.
In the course of my chemical research, I well know that the synonyms of this substance reflect the process of academic cognition of its structure and nature. Either due to different research focuses or differences in the order of discovery, the synonyms are rich and diverse. The trade name is determined by the enterprise in its marketing activities, which has the effect of both logo and publicity.
2 - Fluoro - 5 - Brocamerrobenzene, with its unique chemical properties, has attracted much attention in the fields of organic synthesis. The clarity of synonyms and trade names helps researchers communicate accurately and promotes the orderly operation of producers. Our generation should study it carefully, explore the scientific and commercial context behind it, and contribute to the development of chemistry.
Safety & Operational Standards
2-Fluoro-5-bromo-nitrobenzene is an important substance in chemical research. Safety and operating standards are of paramount importance when it is used and studied.
First word safety. This substance is dangerous or harmful to human health and the environment. Therefore, researchers need to be aware of its physical and chemical properties and understand its latent risks. When operating, appropriate protective equipment, such as gas masks, protective gloves, goggles, etc., must be worn to prevent it from coming into contact with the skin and respiratory tract. The laboratory should also be well ventilated and equipped with an exhaust gas treatment device to prevent it from escaping into the atmosphere, causing environmental pollution and personal injury.
The following operating specifications. When taking 2-fluoro-5-bromo nitrobenzene, use a suitable measuring tool according to the accurate measurement method to ensure the accuracy of the experiment. Mixing, reaction and other operations should follow the established procedures to control temperature, time and speed to prevent accidental reactions. The reaction device should be stable, and its tightness and safety should be checked regularly. After the experiment, the remaining substances and waste should be disposed of in accordance with regulations and should not be discarded at will to ensure environmental safety.
Furthermore, in terms of storage, 2-fluoro-5-bromo-nitrobenzene should be placed in a cool, dry and ventilated place, protected from fire, heat and oxidants. Classified storage, clearly marked, easy access and management.
In short, in the research work of 2-fluoro-5-bromo-nitrobenzene, strict adherence to safety and operating standards can ensure the smooth operation of the experiment, protect the safety of personnel and maintain the good environment.
Application Area
2-Fluoro-5-bromo-nitrobenzene is also a wonder of transformation. It is widely used and cannot be underestimated. In the field of medicine, it is often an important material for making special and good medicines, helping doctors treat diseases. In the field of agrochemical, it can be used as the foundation for creating high-efficiency agricultural agents, protecting crops for a bumper harvest. In the field of material science, it helps to develop novel functional materials, making utensils have extraordinary properties. This compound, with its unique structure and lively chemistry, has attracted researchers to explore it. It is expected to develop its extraordinary ability in various application fields, contributing to the progress of the world and adding bricks and tiles to the great power of chemical creation.
Research & Development
Recently, the research on 2 - Fluoro - 5 - Brocamerrobenzene is of great importance to my research. The synthesis of this compound has been painstakingly explored. At the beginning, I still tried it, but the yield was quite low and impurities were abundant. Then I dedicated myself to studying, consulted countless classics, studied various reaction conditions in detail, adjusted the ratio of reagents, and improved the reaction process.
After months of work, I finally got the method of optimization. Under the new approach, the reaction is controllable, the yield is gradually increasing, and the purity of the product is also good. On this basis, explore its properties and applications. After repeated tests, it shows that it has great potential in many fields, such as pharmaceutical synthesis, which can be used as a key intermediate, which is expected to help the research and development of new drugs; in materials science, it may be able to improve material properties.
I will continue to make progress and explore its mysteries in depth, with the aim of promoting the wide application of this object and contributing to the development of research.
Toxicity Research
Today there is a thing called 2 - Fluoro - 5 - Brocamerrobenzene. I am a chemical researcher to explore its toxicity. This substance contains fluorine, bromine and nitro groups, which are chemically active or toxic.
Fluorine is small and has strong electronegativity, which can change the physical properties of molecules, increase its fat solubility, and easily enter organisms. Bromine atoms are large, which affects the spatial conformation and reactivity of molecules. Nitro has strong electron absorption, which increases the polarity of molecules, or participates in chemical reactions in the body, which impairs the normal function of cells.
Looking at past experiments, substances with this structure may disturb cell metabolism and cause cell damage. 2 - Fluoro - 5 - Brocamerrobenzene may also have similar harm, damage to body tissues, and induce biochemical disorders. Although the toxicological picture is not detailed, its structure shows that toxicity studies cannot be ignored.
Future Prospects
Today there is a thing called 2 - Fluoro - 5 - Brocamerrobenzene. Looking at its properties, it can be used in various chemical synthesis, and the prospect is particularly promising.
My generation is engaged in chemical research, and I often think about the future expansion of this thing. Or it can be used to create new medicines, cure all kinds of diseases, and save people from diseases; or it can help the refinement of electronic materials, make devices more ingenious and flexible, and lead the new trend of technology.
Although its application is still limited today, I firmly believe that with time and unremitting research, more potential will be discovered. In the future, 2 - Fluoro - 5 - Brocamerrobenzene will surely shine brightly, leaving a strong imprint in various fields of chemical industry, such as medicine, materials, etc., for the well-being of the world and for the advancement of science and technology.
Where to Buy 2-Fluoro-5-Bromonitrobenzene in China?
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Frequently Asked Questions

As a leading 2-Fluoro-5-Bromonitrobenzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

What are the main uses of 2-fluoro-5-bromonitrobenzene?
The main use of 2-% Jiang-5-hydroxytryptamine indole is to regulate many physiological functions.
It has a significant effect in the nervous system. It can regulate mood and emotion, make mood peaceful and stable. If the content of this substance is unbalanced, it often causes emotional disorders, such as depression, anxiety and other diseases. If people are worried and stressed for a long time, it is easy to cause abnormal secretion of 2-% Jiang-5-hydroxytryptamine indole, and they are depressed, lack of interest, and upset.
It also has important functions in the digestive system. It can regulate gastrointestinal peristalsis and ensure the orderly digestive process. If its function is abnormal or causes gastrointestinal dysfunction, see diarrhea, constipation and other diseases. Therefore, maintaining the normal level of this substance in the digestive system is crucial for digestive health.
Furthermore, it also affects the regulation of sleep cycles. An appropriate amount of 2-% Jiang-5-hydroxytryptamine indole can help sleep, make people sleep peacefully and get a good rest. If it is insufficient, it may cause sleep problems such as insomnia and dreaminess, which affects the mental state and quality of life during the day.
In addition, in the cardiovascular system, 2-% Jiang-5-hydroxytryptamine indole has the function of regulating vascular tension and is related to the stability of blood pressure. Its level is moderate, which can maintain normal blood vessels and ensure smooth blood circulation.
From this perspective, although 2-% Jiang-5-hydroxytryptamine indole is small, it plays an indispensable role in many aspects of human physiological operation. Maintaining its normal level is of great significance to human health.
What are the physical properties of 2-fluoro-5-bromonitrobenzene?
2-%E6%B0%9F-5-%E6%BA%B4%E7%A1%9D%E5%9F%BA%E8%8B%AF%E7%9A%84%E7%89%A9%E7%90%86%E6%80%A7%E8%B4%A8%E5%A6%82%E4%B8%8B%EF%BC%9A
This medicinal stone is cold in nature. Its quality is heavy, and it is held in the hand, and it has a falling feel, like the thickness of mountains and rivers. Looking at its appearance, the color is dark, and there are textures between it, like the marks engraved by the years.
When thrown into the water, it can be seen that it sinks slowly, not floating or impatient, like a calm person. Put it on the fire and roast, the medicinal stone heats slightly, exudes a trace of coolness, and its cold properties can suppress the fire. If hit with a hard object, the medicinal stone can make a crisp sound, and the sound travels far away. Its texture is solid, broken but not broken, broken but not scattered.
Smell it, the breath is slightly fishy, it seems to have the smell of the deep sea, and it also contains the breath of mountains and rivers of soil. This unique breath is the proof of its passage through time and natural creation. Taste it, the entrance is bitter, its taste is strong, the root of the tongue is full of water, and the bitter taste is long-lasting, which is impressive.
Its electrical conductivity is weak, and there is little current passing through the circuit, just like an insulating thing, and it does not blend with other things at will. However, its heat conduction is acceptable. If you caress it with your hands, you will feel cold at first, but it will be suitable for body temperature for a long time. It is not suddenly cold and hot, and has a harmony.
This 2-%E6%B0%9F-5-%E6%BA%B4%E7%A1%9D%E5%9F%BA%E8%8B%AF%E7%9A%84%E7%89%A9%E7%90%86%E6%80%A7%E8%B4%A8, with cold, heavy, solid, bitter taste and other characteristics, in various applications, all rely on its unique material properties to play a role, in medical, utensil and other aspects, each has its own use, is the wonder of heaven and earth creation.
What are the chemical properties of 2-fluoro-5-bromonitrobenzene?
2-% Jiang-5-hydroxyproline is an organic compound with special chemical properties. Its appearance is often white crystalline powder, which is quite stable at room temperature and pressure.
In terms of solubility, 2-% Jiang-5-hydroxyproline is slightly soluble in water, which is closely related to its molecular structure. There are both hydrophilic groups in its molecule, which can form hydrogen bonds with water molecules and contain a certain hydrophobic part, resulting in limited solubility in water.
In terms of chemical activity, the hydroxyl group in 2-% Jiang-5-hydroxyproline has a certain reactivity. Under suitable conditions, the hydroxyl group can participate in the esterification reaction and react with acid compounds to form corresponding esters. At the same time, the imino group in the proline structure can also participate in a variety of reactions, such as condensation reaction with aldehyde compounds to form nitrogen-containing heterocyclic compounds.
In vivo, 2-% Jiang-5-hydroxyproline is an important component of collagen. Its special structure is of great significance to the high-level structural stability of collagen. Due to its existence, collagen forms a unique three-stranded helix structure, which endows collagen with high strength and toughness. In many physiological processes in organisms, such as tissue construction, wound healing, etc., 2-% Jiang-5-hydroxyproline plays a key role.
In chemical reactions, 2% Jiang-5-hydroxyproline can participate in asymmetric catalytic reactions as a chiral ligand due to its own structural characteristics. Using its chiral center, it can induce the reaction to proceed in a specific direction and obtain high optical purity products, which has shown important application value in the field of organic synthesis.
What are the synthesis methods of 2-fluoro-5-bromonitrobenzene?
To prepare di-hydroxy-5-carboxybenzylquinine, there are three methods, which are described as follows:
First, starting with o-hydroxybenzaldehyde and diethyl malonate, in ethanol, catalyzed by adding hexahydropyridine, condensed to obtain ethyl o-hydroxycinnamate. Then the carbonyl group is reduced with sodium borohydride, and then hydrolyzed and acidified to obtain the target precursor. This body is condensed with m-toluidine in sulfuric acid medium, and then oxidized and cyclized to obtain di-hydroxy-5-carboxybenzylquinine. The raw materials for this route are easy to obtain, the reaction conditions are mild, but the steps are slightly complicated, and the total yield is still good.
Second, with 2-hydroxy-5-methylbenzoic acid as the base, first esterified to obtain the corresponding ester. The ester and bromine are brominated under light, and bromine atoms are introduced. Then coupled with quinoline derivatives in an alkaline environment, and then hydrolyzed ester groups to obtain acidified products. This method is simple, but the bromination step needs to strictly control the conditions, otherwise there will be many side reactions, which will affect the yield and purity.
Third, resorcinol and glyoxylic acid are used as the starting materials, condensed under acidic conditions to form key intermediates. The intermediate reacts with o-aminobenzonitrile, through cyclization, hydrolysis and other steps, and finally obtains di-hydroxy- 5-carboxybenzylquine. This approach is novel, and the raw materials are common. However, some reaction conditions are harsh, and the equipment requirements are high, and suitable catalysts need to be explored to improve the reaction efficiency and selectivity.
All these three methods have their own advantages and disadvantages. In actual preparation, when considering the availability of raw materials, cost, equipment conditions and yield purity, the choice is made.
What are the precautions for storing and transporting 2-fluoro-5-bromonitrobenzene?
2-% E6% B0% 9F - 5-%E6%BA%B4%E7%A1%9D%E5%9F%BA%E8%8B%AF%E5%9C%A8%E5%82%A8%E5%AD%98%E4%B8%8E%E8%BF%90%E8%BE%93%E4%B8%AD%E5%BF%85%E9%A1%BB%E6%B3%A8%E6%84%8F%E5%90%84%E7%A7%8D%E4%BA%8B%E9%A1%B9 to prevent its deterioration and damage to ensure its effectiveness.
When storing, the first environment should be selected. Choose a cool, dry and well-ventilated place. Both are afraid of moisture, and moisture can easily cause 2-% E6% B0% 9F to rot and 5-%E6%BA%B4%E7%A1%9D%E5%9F%BA%E8%8B%AF deteriorate. If placed in a humid place, 2-% E6% B0% 9F or mildew, losing its original properties; 5-%E6%BA%B4%E7%A1%9D%E5%9F%BA%E8%8B%AF may also change the structure due to moisture, which greatly reduces its effectiveness. And the temperature also needs to be suitable. If the temperature is too high, it may cause the components to evaporate and decompose, and if it is too low, it may freeze, affecting the quality.
Furthermore, storage containers are essential. Use clean, sealed containers. Clean can prevent impurities from mixing and polluting both; sealed can block the intrusion of external moisture, air, etc. If the container is not sealed, 2-% E6% B0% 9F is volatile, 5-%E6%BA%B4%E7%A1%9D%E5%9F%BA%E8%8B%AF or react with the components in the air, resulting in quality degradation.
During transportation, stability and protection are essential. Handle with care to avoid collisions and bumps. 2-% E6% B0% 9F texture or fragile, violent collision or damage and leakage; although the 5-%E6%BA%B4%E7%A1%9D%E5%9F%BA%E8%8B%AF is relatively stable, it may be too bumpy or affect its internal structure. During transportation, it should also maintain a suitable environment, and the temperature and humidity should meet the storage requirements. If the journey is long, it is necessary to closely monitor environmental changes and adjust them in a timely manner to ensure that the quality of 2-% E6% B0% 9F-5-%E6%BA%B4%E7%A1%9D%E5%9F%BA%E8%8B%AF is not damaged, and to ensure that it can play its due role in subsequent use.