Hongda Chemical
Products
Home  /  Products  / 

2-Fluoro-4-Nitrobenzene

2-Fluoro-4-Nitrobenzene

Hongda Chemical

Specifications

HS Code

405324

Chemical Formula C6H3FNO2
Molecular Weight 155.09
Appearance Yellow - brown solid or liquid
Boiling Point 208 - 210 °C
Melting Point 27 - 29 °C
Density 1.406 g/cm³
Solubility Slightly soluble in water, soluble in organic solvents like ethanol, ether
Flash Point 87 °C
Vapor Pressure Low at room temperature
Odor Pungent odor
Stability Stable under normal conditions but may react with strong oxidizing agents

As an accredited 2-Fluoro-4-Nitrobenzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

Packing & Storage
Packing 250g of 2 - fluoro - 4 - nitrobenzene packaged in a sealed, chemical - resistant bottle.
Storage 2 - fluoro - 4 - nitrobenzene should be stored in a cool, dry, well - ventilated area away from heat sources and open flames. Keep it in a tightly sealed container to prevent vapor leakage. Store it separately from oxidizing agents, reducing agents, and incompatible substances to avoid potential chemical reactions. Label the storage clearly for easy identification and safety.
Shipping 2 - fluoro - 4 - nitrobenzene is shipped in sealed, corrosion - resistant containers. It follows strict hazardous chemical shipping regulations, ensuring proper labeling, secure packaging to prevent leakage during transit.
Free Quote

Competitive 2-Fluoro-4-Nitrobenzene prices that fit your budget—flexible terms and customized quotes for every order.

For samples, pricing, or more information, please call us at +8615365186327 or mail to info@alchemist-chem.com.

We will respond to you as soon as possible.

Tel: +8615365186327

Email: info@alchemist-chem.com

2-Fluoro-4-Nitrobenzene 2-Fluoro-4-Nitrobenzene
General Information
Historical Development
2 - Fluoro - 4 - Nitrobenzene is an important compound in organic synthesis. Tracing its historical development, early chemists explored the structure and reaction of organic matter and worked tirelessly. In the past, organic synthesis techniques were not refined, and it was quite difficult to obtain this compound. However, the forefathers chemists worked hard and after countless experiments, they finally found a way to synthesize it. At the beginning, the synthesis steps were complicated and the yield was low. With the passage of time, science and technology have advanced, and chemical theory and experimental methods have been sublimated. The advent of new catalysts and the optimization of reaction conditions have made the synthesis of 2-Fluoro-4-Nitrobenzene increasingly simple and efficient, and the yield and purity have been greatly improved. It has played an increasingly critical role in the field of organic synthesis, laying a solid foundation for many subsequent chemical research and industrial applications.
Product Overview
2 - Fluoro - 4 - Nitrobenzene is an important chemical substance. It has a unique structure, with fluorine atoms and nitro groups attached to the benzene ring. This substance has a specific appearance or color state, and is quite useful in the field of chemical synthesis.
Its preparation method or through specific chemical reaction steps. First, benzene is used as the initial raw material, and fluorine atoms are introduced; then nitrification is carried out, and nitro is added. After this series of reactions, this target product is obtained.
Its properties are also characteristic. Due to the electronic effect of fluorine and nitro groups, it affects the electron cloud distribution of benzene ring, resulting in its chemical activity different from benzene. In organic synthesis, it can be used as a key intermediate to participate in a variety of reactions, such as nucleophilic substitution reactions, laying the foundation for the construction of complex organic molecular structures, and has potential applications in pharmaceutical chemistry, materials science and other fields.
Physical & Chemical Properties
2 - Fluoro - 4 - Nitrobenzene is an organic compound. Its physical and chemical properties are quite specific. Looking at its shape, at room temperature, it is a colorless to light yellow liquid with a special odor. Its boiling point is about 200 degrees Celsius. This temperature allows it to change from liquid to gaseous under specific conditions, showing the characteristics of physical changes.
When it comes to solubility, it is slightly soluble in water, but easily soluble in many organic solvents, such as ethanol, ether, etc. This is the embodiment of its chemical affinity. In terms of chemical properties, it has considerable reactivity because of its fluorine and nitro functional groups. The presence of nitro groups decreases the electron cloud density of the benzene ring, making it more prone to nucleophilic substitution reactions. Although fluorine atoms have strong electronegativity, they also endow molecules with unique reaction paths. The various physical and chemical properties of this compound have important research value and application prospects in the field of organic synthesis.
Technical Specifications & Labeling
2 - Fluoro - 4 - Nitrobenzene is an important chemical raw material, and its preparation process and standards are crucial. The process standard needs to carefully study its synthesis path, the selection of raw materials must be pure, and the reaction conditions such as temperature, pressure, and catalyst dosage should be precisely controlled. The reaction temperature should be maintained in a specific range. If it is too high or causes frequent side reactions, if it is too low, the reaction will be slow. The pressure also needs to be matched to ensure that the reaction is carried out efficiently. The type and dosage of catalyst also have a great impact on the reaction rate and product purity.
In terms of product labeling, its chemical name, molecular formula, molecular weight, purity and other key parameters should be clearly marked. Appearance, odor and other characteristics should also be explained in detail. And it is necessary to attach necessary safety warnings, such as the harm of the substance to the human body, protective measures, etc., to ensure that the user can operate correctly and avoid risks, so that the production and application of 2-Fluoro-4-Nitrobenzene can be orderly and safe.
Preparation Method
If you want to make 2 - Fluoro - 4 - Nitrobenzene now, you need to study the method of preparation in detail. The choice of raw materials is fundamental. Fluoride can be used as a base with benzene compounds containing nitro groups. Fluoride needs to be pure and free of impurities in order to maintain the positive reaction. Benzene containing nitro groups must also be carefully selected to avoid impurities.
The beauty of the preparation method lies in the reaction step. First mix the two substances at a suitable temperature, so that they can touch each other slowly. Control the temperature to a certain degree and do not overdo it. In the meantime, observe the state of the reaction. If there is any abnormality, adjust it quickly.
The catalytic mechanism cannot be ignored. Choose a suitable catalyst to promote the reaction to go faster. The dosage is accurate, more random, less slow.
After various steps, after the reaction is completed, it is purified by a wonderful method. Or distillation, or extraction, to remove its impurities, to obtain pure 2-Fluoro-4-Nitrobenzene. In this way, it is a good way to make this thing.
Chemical Reactions & Modifications
F 2 - Fluoro - 4 - Nitrobenzene is also an organic compound. Its chemical reaction and modification are of great importance to scholars.
Looking at its reaction, the properties of fluorine atoms and nitro groups affect its transformation. Fluorine has strong electronegativity, the density of the o-para-electron cloud changes, and the electrophilic substitution is special. Nitro is an electron-withdrawing group, which also changes the activity of the benzene ring. In combination, the reaction path is different from that of benzene.
As for modification, it can attract other groups and change its properties to suit its use. or solubilization, or strong stability, or new energy. If attacked with nucleophiles, fluorine can easily become other groups, and new compounds can be obtained, and the properties are changed. This has great hope in the fields of medicine and materials, and it needs to be deeply studied by scholars.
Synonyms & Product Names
2 - Fluoro - 4 - Nitrobenzene is also a chemical material. Its name is the same, and it is also important in the world. There are more than one thing, both ancient and modern, especially for chemical products. The same name of this product may be different due to research and regional differences.
As far as 2 - Fluoro - 4 - Nitrobenzene is concerned, its or other names all refer to the same thing. The existence of the same name is convenient for all parties to communicate, so that researchers in the field can understand what it refers to. And in business, the trade name is also the same. Different merchants, or according to their needs, take different names, and then investigate their origins, all of which are 2 - Fluoro - 4 - Nitrobenzene. Therefore, it is of great benefit to know the same name and product name, for research and business.
Safety & Operational Standards
2 - Fluoro-4 - Nitrobenzene is a common compound in chemical research and is widely used in many fields. However, during its production and use, safety and operating standards are of paramount importance, which is related to personnel safety and environmental stability.
This compound has certain toxicity and irritation. When operating, the experimenter must first wear complete protective equipment, such as protective clothing, gloves, goggles, etc., to prevent skin contact and eye splashing. Respiratory protection is also indispensable. It is necessary to work in a well-ventilated place or use a gas mask to avoid inhaling its volatile gaseous substances.
For storage, 2 - Fluoro-4 - Nitrobenzene should be stored in a cool, dry and well-ventilated place, away from fire and heat sources. It needs to be stored separately from oxidizing agents, reducing agents, acids, alkalis, etc., and must not be mixed to prevent dangerous chemical reactions. The storage area should be equipped with suitable materials to contain leaks.
In the unfortunate event of a leak, personnel in the leaked contaminated area should be quickly evacuated to a safe area and quarantined to strictly restrict access. Emergency personnel must wear self-contained positive pressure breathing apparatus and anti-toxic clothing. Do not let leaks come into contact with combustible substances (such as wood, paper, oil, etc.). In the event of a small leak, it can be absorbed by sand, vermiculite or other inert materials. A large number of leaks need to be built embankments or excavated for containment, covered with foam to reduce vapor disasters, and then transferred to a tanker or special collector by pump, recycled or transported to a waste treatment site for disposal.
When using 2-Fluoro-4-Nitrobenzene for experimental operations, it is necessary to strictly follow the established operating procedures and precisely control the reaction conditions, such as temperature, pressure, reaction time, etc. After the experiment, the remaining compounds and reaction products should be properly disposed of and not discarded at will to avoid pollution to the environment. In short, only by strictly observing safety and operating standards can we ensure the smooth development of 2-Fluoro-4-Nitrobenzene related work and ensure the safety of personnel and the environment.
Application Area
Today there is a product, named 2 - Fluoro - 4 - Nitrobenzene. This product is useful in many fields.
In the path of medicine, it can be used as a raw material to help create new drugs. Because of its special structure, it can participate in various reactions, paving the way for the synthesis of special drugs. Doctors may use it to heal diseases and save lives.
In the field of materials, it also has potential. It can be integrated into new materials and endowed with unique properties. Or increase the stability of the material, or add its special optical and electrical properties, so that the material can be used in electronics, optical equipment, etc., and shine.
In chemical production, it is a key material. Through exquisite craftsmanship, it is transformed into a variety of products to meet the needs of all parties and promote the vigorous progress of the chemical industry. This 2-Fluoro-4-Nitrobenzene is actually widely used and has extraordinary value in many industries.
Research & Development
I am committed to the research of 2 - Fluoro - 4 - Nitrobenzene. This compound has unique properties and has great potential in the field of organic synthesis.
At first, I investigated its molecular structure in detail, and understood the wonder of its bonding and the checking point of its activity. After various experiments, I measured its physical properties, such as melting point and boiling point, and explored its chemical stability.
Then, study its synthesis method. Try various raw materials and paths to obtain an efficient method. Or optimize the reaction conditions, control temperature, adjust pressure, and select catalysts, and strive to improve yield and purity.
I also think about its application and expansion. Looking at its potential in the fields of medicine, materials, etc., it is hoped that it can open up new avenues, promote its wide use, and make progress in scientific research and industry. This will add new colors to the academic and industrial circles, promote its sustainable development, and make its potential fully available to the world.
Toxicity Research
Recently, it has been a lot of effort to study the toxicity of "2-Fluoro-4-Nitrobenzene". This substance may seem ordinary, but its properties are different. After various experiments, white mice were tested and fed food containing this substance. Soon, the white mice gradually became sluggish, their movements were slow, and their hair lost its luster.
Looking at its effects on plants, planted in the soil containing this substance, the germination was slow, the leaf color was yellowing, and the growth was greatly blocked. It can be seen that "2-Fluoro-4-Nitrobenzene" is significantly toxic and hinders the growth and development of organisms. The purpose of research is to clarify its harm, and to find ways to avoid it in the future, so as to protect sentient beings from its poison.
Future Prospects
2 - Fluoro - 4 - Nitrobenzene is also a chemical product. The future prospects of this compound are not promising. This compound is in the field of multi-domain or energy exposure.
In the field of research, it may be the cornerstone of new research. With its characteristics, it may be able to make the molecule of the material, which can help the treatment of diseases. In the field of materials, it may also be special and give new properties to the material, such as improving the quality and performance of the material.
And with the increasing technology, the research method must also be refined. It may not be possible to synthesize this product more efficiently and with better land retention, increasing the quantity and reducing the cost. In this way, its application will be more general, and it will be of great help to our development. It will help us to expand a new world, and we can expect it to be widely used in the future, and promote the steps of each line of work.
Where to Buy 2-Fluoro-4-Nitrobenzene in China?
As a trusted 2-Fluoro-4-Nitrobenzene manufacturer, we deliver: Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements. Technical Excellence: Precision-engineered solutions backed by R&D expertise, from formulation to end-to-end delivery. Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.
Frequently Asked Questions

As a leading 2-Fluoro-4-Nitrobenzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

What are the main uses of 2-Fluoro-4-Nitrobenzene?
2-Fluoro-4-nitrobenzene is also an organic compound. It has a wide range of uses and is involved in various fields of chemical industry.
In the synthesis of medicine, 2-fluoro-4-nitrobenzene can be an important intermediate. Physicians make special drugs, often rely on this as the basis, and through complex reactions, they are transformed into ingredients with unique curative effects. Such as the preparation of antibacterial and anti-cancer agents, which may be the key starting material to help form the precise structure of drug molecules to achieve the ability to cure diseases.
It is also indispensable in the creation of pesticides. Farmers want to protect crops and prevent pests and diseases, 2-fluoro-4-nitrobenzene can be used in pesticide formulations. After chemical changes, it has the equivalent of insecticides, sterilization, and weeding, which can protect the growth of farmland crops, increase their yield, and maintain their quality.
Furthermore, in the field of materials science, it is also possible. For example, the development of special polymer materials, 2-fluoro-4-nitrobenzene participates in the reaction, which can change the characteristics of materials and give them properties such as heat resistance, corrosion resistance, and electrical specificity to meet the strict needs of high-end fields such as electronics and aerospace.
In summary, although 2-fluoro-4-nitrobenzene is a tiny organic compound, it is a key factor in many important fields such as medicine, pesticides, and materials. It has far-reaching impact on human life and industrial development, and has great practical value. It is an important cornerstone for the development of the chemical industry.
What are the physical properties of 2-Fluoro-4-Nitrobenzene?
2-Fluoro-4-nitrobenzene is also an organic compound. It has various physical properties, which are described in detail below.
First of all, under normal temperature, 2-fluoro-4-nitrobenzene is a light yellow to yellow liquid, and it can be seen that it is clear and has a specific color. The characterization of this color state is one of the important basis for identifying this substance.
When it comes to the melting point, it is about -2 ° C. The melting point is also the critical temperature at which a substance changes from a solid state to a liquid state. When the ambient temperature rises to about -2 ° C, 2-fluoro-4-nitrobenzene melts from a solid state to a liquid state. This melting point value is of critical significance in many aspects such as chemical practice, material separation and identification.
The boiling point is related to the temperature at which a substance changes from liquid to gaseous under a specific pressure. The boiling point of 2-fluoro-4-nitrobenzene is about 219 ° C. At this temperature, if energy is continuously supplied, a large amount of its liquid will be converted into a gas and escape. Knowing the boiling point is essential in processes such as distillation and purification.
Its density is about 1.448g/cm ³, which indicates the mass of the substance per unit volume. Density characteristics are important for the analysis of phenomena such as mixing and delamination of substances, as well as the design of related chemical processes.
Furthermore, 2-fluoro-4-nitrobenzene is insoluble in water. Water is a common solvent, and this substance has poor solubility with water and is easy to form a phase of its own in aqueous solution. However, it is soluble in organic solvents such as ethanol and ether. This solubility property provides a basis for selecting a suitable solvent in organic synthesis reactions, and also helps to separate and purify the substance from the mixture.
In addition, 2-fluoro-4-nitrobenzene is volatile to a certain extent and can evaporate slowly in the air. Due to the presence of fluorine, nitro and other functional groups in the structure, it has a specific odor and can be smelled. This volatile and odor characteristic is relevant to safety protection and environmental monitoring in the actual operating environment.
What is the chemistry of 2-Fluoro-4-Nitrobenzene?
2-Fluoro-4-nitrobenzene is also an organic compound. It has unique chemical properties and is very important in many chemical reactions and synthesis fields.
In this compound, the presence of fluorine atoms and nitro groups has a deep impact on its chemical behavior. Fluorine atoms have high electronegativity, which can change the electron cloud density distribution of the benzene ring, cause the electron cloud density of the benzene ring to decrease, and make the electrophilic substitution reaction activity change. It makes it more difficult for the adjacent and para-position of the benzene ring to undergo electrophilic substitution than the interposition, and the reaction check point is more inclined to the interposition.
Furthermore, the nitro group is a strong electron-absorbing group, which further strengthens the reduction effect of the electron cloud density of the benzene ring. The synergy of the two makes the electrophilic substitution activity of 2-fluoro-4-nitrobenzene significantly lower than that of benzene. However, in the nucleophilic substitution reaction, the existence of the two creates favorable conditions for the reaction. Because the nitro group and the fluorine atom absorb electrons, the electron cloud density of the benzene ring carbon atom is reduced, and it is more vulnerable to the attack of nucleophilic reagents. Especially the carbon atom connected to the fluorine atom is enhanced by the influence of the nitro group, and the nucleophilic substitution reaction is easy to occur here.
In the reduction reaction, the nitro group can be reduced to an amino group, and important intermediates such as 2-fluoro-4-aminobenzene are derived, which are widely used in medicine, pesticides and dye synthesis. And 2-fluoro-4-nitrobenzene can participate in coupling reactions, etc., and is a key raw material for the construction of complex organic molecular structures. Its unique chemical properties stem from the change of the electronic structure of fluorine atoms and nitro-p-benzene rings, which provide diverse possibilities for organic synthetic chemistry and are of great value in many fields of the chemical industry.
What are 2-Fluoro-4-Nitrobenzene synthesis methods?
The synthesis method of 2-fluoro-4-nitrobenzene is widely recorded in ancient books. In the past, the method may have started with benzene, first nitrifying, introducing nitro groups, then halogenating, and introducing fluorine atoms. Although this method can be followed, the steps are complicated, and during halogenation, side reactions occur frequently, resulting in impure products and poor yields.
There are also those who use 2-fluoroaniline as raw material, first diazotization, and then reaction with nitrite to introduce nitro groups. Although this method can be achieved, the diazotization reaction conditions are strict, and low temperature and careful operation are required, otherwise it is easy to produce danger, and the reagents used are mostly toxic and harmful to the environment.
Another method of reacting 4-nitrophenylboronic acid with fluorinated reagents. This way, with the help of metal catalysis, the reaction conditions are relatively mild, the selectivity is also good, the yield is considerable, and it is friendly to the environment. It has gradually become a common way to synthesize 2-fluoro-4-nitrobenzene at present.
Or, with halogenated nitrobenzene as a substrate, fluorine atoms are introduced through nucleophilic substitution reaction. The key to this method is to choose the appropriate nucleophilic reagents and reaction conditions to make the reaction efficient and less by-products. However, the difference in the activity of halogenated nitrobenzene also affects the reaction process and needs to be carefully regulated.
Looking at all the synthesis methods, each has its advantages and disadvantages. Today's chemists are still seeking more efficient, green and simple methods for synthesizing 2-fluoro-4-nitrobenzene.
What are the precautions in storage and transportation of 2-Fluoro-4-Nitrobenzene?
2-Fluoro-4-nitrobenzene is a chemical commonly used in organic synthesis. When storing and transporting this product, be sure to pay attention to the following matters.
First words storage. Because of its certain chemical activity, it should be placed in a cool, dry and well-ventilated place. If the environment is humid, it may react with water vapor, which will damage the quality; if the temperature is too high, it may also cause unstable conditions and even cause dangerous accidents. And it must be stored separately from oxidizing agents, reducing agents, alkalis and other substances to prevent interaction. Cover 2-fluoro-4-nitrobenzene is mixed with oxidizing agents, or there is a risk of violent reaction, resulting in serious consequences such as combustion and explosion; contact with reducing agents may also cause unpredictable chemical reactions. At the same time, clear warning signs should be set up in the storage area, so that personnel can know that this is a dangerous chemical, and non-professionals should not approach it.
Second talk about transportation. When transporting 2-fluoro-4-nitrobenzene, the container used must be strong and well sealed to prevent leakage. Leaks not only cause chemical damage, but also pose a threat to the environment and surrounding personnel. Transportation vehicles must also meet the standards for the transportation of hazardous chemicals and be equipped with necessary emergency treatment equipment, such as fire extinguishers, adsorption materials, etc. In case of leakage, adsorption materials can be used to deal with it in time to prevent proliferation; and fire extinguishers can deal with possible fires. Transport personnel should also be professionally trained to be familiar with the properties, hazards and emergency treatment methods of 2-fluoro-4-nitrobenzene. In this way, in case of emergencies, they can respond calmly and take appropriate measures to ensure the safety of the transportation process.