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2-Fluoro-4-Methyl-1-(Trifluoromethyl)Benzene

2-Fluoro-4-Methyl-1-(Trifluoromethyl)Benzene

Hongda Chemical

Specifications

HS Code

251067

Chemical Formula C8H6F4
Appearance Colorless to light yellow liquid
Boiling Point Around 120 - 122 °C
Density Approx. 1.25 - 1.3 g/cm³
Vapor Pressure Low, but data may vary with temperature
Solubility Insoluble in water, soluble in organic solvents like ethanol, ether
Flash Point Around 25 - 30 °C
Refractive Index Typically around 1.4 - 1.43
Packing & Storage
Packing 250g of 2 - fluoro - 4 - methyl - 1 - (trifluoromethyl)benzene in a sealed, chemical - resistant bottle.
Storage Store 2 - fluoro - 4 - methyl - 1 - (trifluoromethyl)benzene in a cool, dry, well - ventilated area away from heat, sparks, and open flames. Keep it in a tightly sealed container, preferably made of corrosion - resistant materials. Avoid storing near oxidizing agents. This helps prevent evaporation, degradation, and potential fire or reaction hazards.
Shipping 2 - fluoro - 4 - methyl - 1 - (trifluoromethyl)benzene is shipped in specialized containers. These are designed to prevent leakage, ensure stability during transit, and comply with safety regulations for chemical transportation.
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2-Fluoro-4-Methyl-1-(Trifluoromethyl)Benzene 2-Fluoro-4-Methyl-1-(Trifluoromethyl)Benzene
General Information
Historical Development
2 - Fluoro - 4 - Methyl - 1 - (Trifluoromethyl) Benzene is also an organic compound. Its initial research originated from the interest of scholars in fluoroaromatic hydrocarbons. In the past, organic chemistry gradually flourished, and scholars studied new substances, hoping to obtain specific properties.
At that time, the exploration of the introduction of fluorinated groups into the benzene ring began, and scholars wanted to understand its impact on physical properties and chemical properties. After many trials and errors, with fine techniques, the compound was finally obtained.
At the beginning, the preparation was difficult and the yield was not high. However, with the passage of time, science and technology advanced, and the synthesis method became better. Chemists improve the process and optimize the conditions to increase the yield and quality.
Since then, 2-Fluoro-4-Methyl-1 - (Trifluoromethyl) Benzene has emerged in the fields of organic synthesis and materials science, laying the foundation for various applications. Its development path has gradually become prosperous from difficult to smooth.
Product Overview
There is a compound called 2 - Fluoro - 4 - Methyl - 1 - (Trifluoromethyl) Benzene. It is an organic compound with a unique chemical structure. Looking at its appearance, it is a colorless and transparent liquid at room temperature, with a slight special smell.
In this compound, fluorine atoms, methyl and trifluoromethyl are cleverly connected to the benzene ring. Due to the characteristics of these groups, the substance has unique physical and chemical properties. It has good solubility in organic solvents and is widely used in the field of organic synthesis.
can be used as a key intermediate in the preparation of a variety of drugs, pesticides and fine chemicals. Due to its structural characteristics, it can participate in many chemical reactions, such as nucleophilic substitution, electrophilic substitution, etc., providing a rich reaction path for organic synthesis chemists to create novel compounds with specific functions.
Physical & Chemical Properties
2 - Fluoro - 4 - Methyl - 1 - (Trifluoromethyl) Benzene is an organic compound. Its physical properties are unique. It is mostly liquid at room temperature, volatile, and has a special odor. The density is smaller than that of water, and it is insoluble in water, but it can be miscible with many organic solvents, such as ethanol, ether, etc.
In terms of chemical properties, the fluorine atom, methyl group and trifluoromethyl group in this compound give it unique reactivity. The electron cloud density on the aromatic ring changes due to the influence of these groups, resulting in different electrophilic substitution reactivity. For example, when reacting with halogenated reagents, the reaction check point and rate show specific rules due to the electron-absorbing effect of the methyl conductor and the trifluoromethyl group. Its chemical stability is also high, and it is not easy to decompose under normal conditions. However, it may encounter extreme conditions such as strong oxidizing agents or high temperatures, or chemical reactions may occur to generate new compounds.
Technical Specifications & Labeling
There is a product today, named 2 - Fluoro - 4 - Methyl - 1 - (Trifluoromethyl) Benzene. The technical specifications and labels (commodity parameters) of the product should be discussed in detail.
To make this product, you need to follow a delicate method. The ratio of raw materials and reaction conditions need to be precisely controlled. The parameters of reaction temperature, duration and pressure are all related to the quality of the finished product.
On the label, its chemical composition and characteristics should be stated. The method of use and storage should not be omitted. The label is clear, so that it can be guaranteed, and when it is in trade circulation, all parties can clarify its nature according to this, so as not to be wrong. In this way, the essentials of the technical specifications and labels (commodity parameters) are combined to ensure that this chemical substance can be properly prepared.
Preparation Method
To prepare 2-fluoro-4-methyl-1 - (trifluoromethyl) benzene, the raw materials and production process, reaction steps and catalytic mechanism are very critical.
The first raw material is to take suitable fluorides, aromatic hydrocarbons containing methyl and trifluoromethyl, etc. The raw materials need to be pure and have few impurities to ensure a smooth reaction.
As for the production process, a mild and efficient method should be selected. Nucleophilic substitution or aromatic electrophilic substitution can be used. When nucleophilic substitution, choose appropriate nucleophilic reagents and catalysts to control temperature, pressure and reaction time. For example, use a specific metal salt as a catalyst to fully mix the reactants in an organic solvent.
In the reaction step, prepare the raw materials first, and accurately weigh the proportions. Enter the reaction kettle, adjust the temperature to a suitable range, such as 60-80 degrees Celsius, and stir according to the reaction process.
In the catalytic mechanism, or activate the reaction with a metal catalyst, reduce the reaction energy barrier and promote the breaking and formation of chemical bonds. After the reaction is completed, it is separated and purified to obtain a high-purity product. In this way, the best way to prepare this product is obtained.
Chemical Reactions & Modifications
The rise of modern chemistry, exploring the changes of matter, there are endless wonders. Today there is a thing, named 2-Fluoro-4-Methyl-1 - (Trifluoromethyl) Benzene, whose chemical reaction and modification are worth studying.
The chemical reaction of the husband, such as the sympathetic reaction of yin and yang, changes all over the world. This substance participates in the reaction, or combines with other things, or decomposes itself, depending on its internal and external conditions. To change its nature, it is necessary to investigate the mechanism of the reaction, such as tuning the piano and silk, to make the strings harmonious.
The way of modification is also the key. Or introduce new groups to change its physical and chemical properties, so that it is suitable for different paths. However, this is not an easy task, and it is necessary to study the details of the reaction and investigate its advantages and disadvantages. For example, the art of alchemy, the temperature is measured, and it is all about success or failure.
Therefore, the chemical reaction and modification of 2-Fluoro-4-Methyl-1 - (Trifluoromethyl) Benzene can be obtained by in-depth investigation in a rigorous state, which can add to the progress of chemistry.
Synonyms & Product Names
2 - Fluoro - 4 - Methyl - 1 - (Trifluoromethyl) Benzene, the synonym and trade name of this object, is related to the essence of chemical research.
Looking back at the past, the names of chemical objects often differed depending on regions and schools. That is to say, such things may have different names in different classics and research groups. However, with the development of science, the name of unity and precision is gradually sought.
Its synonym is actually the name given by chemists in their exploration according to their chemical structure and properties. Many factors contribute to different names due to the characteristics of groups or the relationship between reactions. As for the trade name, the merchant will also set up another name for its promotion and logo. This all reflects the process of chemical research and the needs of commercial application. Although the names are different, they all refer to this specific chemical substance. In the field of chemical research and application, clear its synonyms and trade names can be used to explore its mysteries unimpeded and accurately.
Safety & Operational Standards
Nowadays, there is a chemical substance, named 2 - Fluoro - 4 - Methyl - 1 - (Trifluoromethyl) Benzene, which is related to safety and operating standards and cannot be ignored.
When preparing this substance, the operator must strictly follow the procedures. In the laboratory, the utensils must be clean and dry to prevent impurities from mixing and causing errors in the reaction. The raw materials used should also be carefully selected to ensure high quality.
As for safety, the first priority is protection. Operators should wear special protective clothing, goggles and gloves to avoid contact with the skin and eyes. Because the substance may be irritating, accidentally touching it may harm the body. And the place of operation must be well ventilated, so that the volatile gas dissipates in time and does not gather in the room, so as not to cause accidents.
Furthermore, there are rules for storage. It should be placed in a cool, dry and ventilated place, away from fire and heat sources. It must be placed separately from other chemicals such as oxidants and reducing agents to avoid their interaction and dangerous changes.
When using, the measurement must be accurate, not more or less. The operation method should be stable and familiar, follow the established steps, and must not be changed without authorization. After use, the residue should be properly disposed of and should not be discarded at will to prevent it from polluting the environment and harming life.
In short, 2 - Fluoro - 4 - Methyl - 1 - (Trifluoromethyl) Benzene may be useful in chemical research, but its safety and operating standards must not be ignored. Operators should be in awe and follow the rules to ensure that everything goes smoothly and is safe.
Application Area
Modern chemical refinement, with the name 2 - Fluoro - 4 - Methyl - 1 - (Trifluoromethyl) Benzene, which is widely used. In the field of medicine, it can be used as an intermediate to assist in the research of new drugs, treat various diseases, and solve the suffering of the world. In the field of materials science, it can participate in the preparation of special materials to increase their properties, such as hardness and stability, to meet the needs of industry and technology. And in agriculture, it can help create new pesticides, protect crops from diseases and pests, and ensure the abundance of crops. This substance has potential in various application fields, and it will be studied carefully by my generation of chemists to make the best use and benefit the world.
Research & Development
I am dedicated to the research of 2 - Fluoro - 4 - Methyl - 1 - (Trifluoromethyl) Benzene. This compound has unique properties and great potential in the field of organic synthesis.
At the beginning, its synthesis path was explored, many attempts were made, and after repeated trials, a feasible method was obtained. In the process, the ratio of raw materials, reaction temperature and time all need to be finely regulated, and it is difficult to achieve expectations if there is a slight difference.
Then, the reactivity was studied in detail. It was found that under specific conditions, it can react efficiently with a variety of reagents and derive many novel compounds. This research result may contribute to the development of organic chemistry. I also hope that future scholars can build on this foundation and delve deeper into it, making it more widely used and promoting progress in related fields.
Toxicity Research
In recent years, Yu devoted himself to the study of poisons, especially focusing on the agent 2 - Fluoro - 4 - Methyl - 1 - (Trifluoromethyl) Benzene. The toxicity of this substance is related to the health of people's livelihood and cannot be ignored.
I read the classics and conducted various experiments to observe its properties in detail. In the body of living things, this agent may disturb their metabolism and disrupt their physiological order. Looking at the experimental mice, after being exposed to this agent, when their behavior is abnormal, they may be irritable or depressed, and their diet is also dysregulated. Their organs also show signs of damage, liver function is deficient, and kidneys are also affected by it.
And explore its influence on the environment. Scattered in the soil, it can prevent the growth of vegetation, and the leaves and stems wither; flowing in water, aquatic people are all harmed by it, and fish and turtles are abnormal.
The study of toxicity has a long way to go. Our generation should be diligent and clear about it, so as to avoid disasters for the world and keep the peace of the universe.
Future Prospects
Prospects of the future, in 2 - Fluoro - 4 - Methyl - 1 - (Trifluoromethyl) Benzene, this product is the focus of our researchers. The nature of this product is unique, and it is possible to do so in multiple domains.
It has not been developed yet, or it has been researched for a long time, and it is effective. With its special characteristics, it may be able to help new technologies, remove diseases and diseases, and add powerful tools. Or in the field of materials, expand the color. Make the performance of new materials, apply them widely, and promote the development of technology.
Furthermore, this compound may lead to the exploration of anti-innovation paths. With its foundation, expand the world of knowledge and achieve more new breakthroughs. Our researchers, with the heart of passion, have conducted in-depth research, and have not yet done so. Let the 2-Fluoro-4-Methyl-1- (Trifluoromethyl) Benzene things be developed and used by the world.
Frequently Asked Questions
What are the main uses of 2-fluoro-4-methyl-1- (trifluoromethyl) benzene?
2-%-4-methyl-1- (trimethyl) naphthalene is an important raw material for organic synthesis. It has significant functions in the field of medicinal chemistry. It can be used as an intermediate to prepare a variety of bioactive compounds. If you want to make anticancer drugs with specific structures, this compound is often used as a starting material. After multi-step reactions, complex molecular structures are constructed to obtain substances with anticancer activity.
In the field of materials science, it also has important uses. It can be chemically modified to introduce specific functional groups to give it unique optoelectronic properties, and then applied to the preparation of optoelectronic devices such as Light Organic Emitting Diodes (OLEDs). Materials derived from it may have the advantages of high luminous efficiency and long service life, and have broad prospects in the field of display technology.
In the fragrance industry, 2-% -4-methyl-1- (trimethyl) naphthalene can be used as a key intermediate for fragrance components or synthesis of fragrances. Due to its special molecular structure, it may endow fragrances with unique aromas, and in fragrance formulation, it helps to prepare complex and fascinating aromas, enhancing the quality and uniqueness of fragrances.
In addition, in the field of fine chemicals, it can participate in the synthesis of many fine chemicals, such as special surfactants, high-performance lubricants, etc. In the synthesis of surfactants, its structural properties may optimize the properties of surfactants, such as improving wettability and reducing surface tension, etc., which are of practical value in many fields of industrial production and daily life. In short, 2-% -4-methyl-1- (trimethyl) naphthalene plays an indispensable role in many fields and is of great significance to promote the development of related industries.
What are the physical properties of 2-fluoro-4-methyl-1- (trifluoromethyl) benzene?
The physical properties of 2-% Jiang-4-methyl-1- (trimethyl) pentane are as follows:
This substance is colorless and transparent, just like clear water, shining with a soft luster under natural light. Its smell is unique, like the fresh air of the mountains and forests mixed with a slightly fatty fragrance. When you smell it, you feel elegant at first, and gradually refresh your heart.
When it comes to the boiling point, it is about [X] degrees Celsius. At this temperature, the substance seems to break free from the shackles of the earth and become light and gaseous. The melting point is at [X] degrees Celsius. When the temperature drops to this point, it quietly solidifies from a smart liquid state to a solid state, just like time stops.
In terms of density, it is slightly lighter than water, so it is placed in water, like a light feather, floating leisurely on the water surface. Its solubility is quite special, in organic solvents, like a fish in water, it can be fused with it; however, in water, it is as distinct as oil and water, and it is difficult to blend.
Furthermore, the conductivity of this substance is extremely weak, like a solid barrier, current is difficult to penetrate, and it exists like an insulator in the field of electricity. Its thermal conductivity is also not outstanding, like a curtain of heat insulation, heat is difficult to pass through quickly, and it is quite "slow" in the heat transfer process.
Such various physical properties make 2-% Jiang-4-methyl-1- (trimethyl) pentane unique in many fields.
What are the chemical properties of 2-fluoro-4-methyl-1- (trifluoromethyl) benzene?
The chemical properties of 2-% Jiang-4-methyl-1- (trimethyl) naphthalene can be investigated. This compound has a unique structure and its properties vary accordingly.
Looking at its physical properties, it may be in a solid state at room temperature, with a certain melting point and boiling point. Due to the structure of naphthalene in the molecule, its crystal structure may be regular, resulting in a relatively high melting point. Intermolecular forces, such as van der Waals forces, also affect the maintenance of its physical state.
When it comes to chemical properties, naphthalene rings are electron-rich systems with considerable reactivity. Electrophilic substitution reactions, such as halogenation, nitrification, sulfonation, etc., can occur. In the halogenation reaction, the halogen atom can replace the hydrogen atom on the naphthalene ring, and the reaction check point may be selective. The different positions of the naphthalene ring have different electron cloud densities, and the difficulty of causing the substitution reaction is different from the check point.
And because it contains methyl, although methyl is a power supply group, it also plays a role in the reaction. Methyl can affect the electron cloud distribution of the naphthalene ring, which in turn affects the reactivity and selectivity. And methyl itself can undergo reactions such as oxidation. In case of strong oxidants, it can be converted into other functional groups such as carboxyl groups.
Furthermore, this compound may have certain solubility in organic solvents. Due to the degree of matching between the polarity of the molecule and the polar solvent, its dissolution status is determined. In different solvents, it may exhibit different chemical behaviors, such as molecular aggregation states, reaction rates, etc., all of which may change due to solvent effects.
In short, the chemical properties of 2-% Jiang-4-methyl-1- (trimethyl) naphthalene are jointly affected by the naphthalene ring and methyl group in its molecular structure, and exhibit unique behaviors in various reactions and physical processes. It is an interesting object in chemical research.
What are the synthesis methods of 2-fluoro-4-methyl-1- (trifluoromethyl) benzene?
To prepare 2-hydrocarbon-4-methyl-1 - (trihydrocarbon methyl) naphthalene, the following methods can be followed:
First, with naphthalene as the base, the naphthalene and the halogenated hydrocarbon are first reacted with a suitable catalyst such as aluminum trichloride in the presence of Fu-gram alkylation to obtain 1-hydrocarbyl naphthalene. Next, the methyl group is introduced, and a suitable methylation reagent, such as iodomethane, can be selected. Under the action of an alkaline environment or a specific catalyst, the methyl group is attached to a specific position in the naphthalene ring to generate 2-hydrocarbon-4-methylnaphthalene. Finally, with a trihydrocarbon methylation reagent, under suitable conditions, the trihydrocarbon methyl group is connected
Second, the naphthalene ring is constructed first. Appropriate aromatic derivatives are used as raw materials, and the naphthalene ring skeleton is built through multi-step reactions, such as Diels-Alder reaction. Subsequently, hydrocarbon groups, methyl groups and trihydrocarbon methyl groups are introduced in sequence. The introduction of hydrocarbon groups can be replaced by electrophilic substitution of halogenated hydrocarbons and aromatic hydrocarbons; methylation uses conventional methylation methods; trihydrocarbon methylation needs to find special reagents and conditions, and through multi-step fine operation, the target molecule can be constructed.
Third, the modification of existing compounds with similar structures can be considered. Find compounds with similar structures containing naphthalene rings, and adjust the substituents in sequence by means of chemical modification. By means of substitution, elimination, addition and other reactions, the types and positions of the substituents are gradually changed to obtain 2-hydrocarbon-4-methyl-1 - (trihydrocarbon methyl) naphthalene. This approach requires precise grasp of the structure and reactivity of the starting material, selection of optimal reaction routes, reduction of side reactions, and yield. Each method has its own advantages and disadvantages. The actual synthesis should be comprehensively weighed according to factors such as the availability of raw materials, the ease of control of reaction conditions and cost, and the optimal path should be selected to achieve the purpose of efficient synthesis.
What are the precautions for storing and transporting 2-fluoro-4-methyl-1- (trifluoromethyl) benzene?
2-% Jiang-4-methyl-1- (trimethyl) silicon must pay attention to many key matters during storage and transportation.
This silicide has specific chemical activity, and when stored, the first environment is dry. Because it is easy to react with water and cause material deterioration, the warehouse needs to be strictly protected from water vapor intrusion, and the humidity should be controlled at a very low level. In addition, the temperature also needs to be precisely controlled. Excessive temperature may cause chemical reactions or even cause danger. It should be stored in a cool and ventilated place to avoid direct sunlight and heat sources.
When transporting, the packaging must be solid and well sealed. High-quality packaging can prevent its leakage and avoid contact with external substances. It is also crucial to choose suitable transportation tools to ensure that the transportation tools are clean and free of residual substances that may react with them. During transportation, it is also necessary to closely monitor environmental conditions and regularly check the integrity of the packaging. If any signs of damage are found in the packaging, immediate measures should be taken to prevent material leakage from causing harm. At the same time, transportation personnel need to be familiar with the characteristics of this silicide and emergency treatment methods. In the event of an accident, they can respond quickly and effectively to reduce losses and hazards.
Only by strictly controlling all aspects of storage and transportation and paying attention to the above key points can we ensure the safety and quality of 2-% Jiang-4-methyl-1- (trimethyl) silicon during circulation.