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2-Fluoro-4-Methoxybenzeneboronic Acid

2-Fluoro-4-Methoxybenzeneboronic Acid

Hongda Chemical

Specifications

HS Code

402911

Chemical Formula C7H8BO3F
Molar Mass 169.95 g/mol
Appearance Solid (usually white or off - white)
Solubility In Water Slightly soluble
Solubility In Organic Solvents Soluble in common organic solvents like dichloromethane, toluene
Melting Point 145 - 149 °C
Purity Typically high - purity grades available, e.g., 97%+
Boiling Point Decomposes before boiling
Stability Stable under normal conditions, but moisture - sensitive

As an accredited 2-Fluoro-4-Methoxybenzeneboronic Acid factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

Packing & Storage
Packing 100g of 2 - fluoro - 4 - methoxybenzeneboronic Acid packaged in a sealed plastic bottle.
Storage 2 - fluoro - 4 - methoxybenzeneboronic acid should be stored in a cool, dry place. Keep it in a well - sealed container to prevent moisture absorption and contact with air, as boronic acids can be sensitive to oxidation and hydrolysis. Store away from heat sources and incompatible substances like strong acids, bases, and oxidizing agents to maintain its chemical integrity.
Shipping 2 - fluoro - 4 - methoxybenzeneboronic acid is shipped in sealed, corrosion - resistant containers. Packaging ensures protection from moisture and physical damage. Shipment follows strict chemical transport regulations for safe delivery.
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2-Fluoro-4-Methoxybenzeneboronic Acid 2-Fluoro-4-Methoxybenzeneboronic Acid
General Information
Historical Development
2 - Fluoro - 4 - Methoxybenzeneboronic Acid is a useful compound in organic synthesis. Looking back in the past, the development process of this compound can be described as gradual. At the beginning, chemists intended to explore boron-containing organic compounds. After many attempts and studies, they embarked on the exploration of specific substituted phenylboronic acids. After gaining insight into the chemical properties of fluorine, methoxy and other groups, they proceeded to synthesize this compound. Early synthesis, due to technical and cognitive limitations, the yield was not high and the purity was poor. However, with the advancement of chemical technology, new synthesis methods have emerged, optimizing reaction conditions, making the synthesis of 2-Fluoro-4-Methoxybenzeneboronic Acid more efficient and accurate. Now it has been widely used in many fields such as medicine and materials, and the prospect is quite promising.
Product Overview
2 - Fluoro - 4 - Methoxybenzeneboronic Acid
2 - Fluoro - 4 - Methoxybenzeneboronic Acid is a compound that we have carefully studied in chemical research. It has a unique chemical structure. On the benzene ring, fluorine atoms and methoxy groups are in binary and quadratic positions, and boron groups are also connected to the benzene ring.
This compound has great potential in the field of organic synthesis. The presence of boron groups allows it to participate in many key reactions, such as the Suzuki reaction, through which various carbon-carbon bonds can be formed, laying the foundation for the synthesis of complex organic molecules. Methoxy groups, as power supply groups, can affect the electron cloud density of the benzene ring, thereby regulating the reactivity and selectivity. The introduction of fluorine atoms not only changes the physical and chemical properties of molecules, such as improving lipophilicity, but also has a potential impact on their biological activity.
In practical applications, 2-Fluoro-4-Methoxybenzeneboronic Acid may be applied in medicinal chemistry to help the development of new drugs; in the field of materials science, it is also expected to be used to prepare materials with unique functions. I will continue to explore more properties and applications to expand the value of this compound in various fields.
Physical & Chemical Properties
2 - Fluoro - 4 - Methoxybenzeneboronic Acid is a unique compound. Its physical and chemical properties are unique. Looking at its appearance, it is often in the form of white to off-white crystalline powder, which is easy to operate and measure in many reaction systems. The value of its melting point is about a specific range, which is of great significance in the identification and purity of substances.
In terms of chemical properties, the presence of boron atoms in this compound gives it unique reactivity. In the field of organic synthesis, it can be used as a key intermediate to participate in many coupling reactions. By ingenious interaction with other organic halides and other reagents, complex organic molecular structures can be constructed. And the fluorine and methoxy functional groups it contains have a great impact on the electron cloud distribution and spatial structure of the molecule, which in turn affects its reaction selectivity and activity. It exhibits certain solubility in common organic solvents, which also provides convenience for its application in various chemical processes.
Technical Specifications & Labeling
About the technical specifications and labels (product parameters) of 2-fluoro-4-methoxyphenylboronic acid
Fu 2-fluoro-4-methoxyphenylboronic acid is the product of our painstaking research. Its technical specifications are related to the quality, which is the most important thing.
When preparing, the raw materials must be carefully selected, and the ratio must be accurate. The temperature and pressure of the reaction need to be controlled according to specific regulations. A slight difference will affect the purity of the product.
In terms of identification, state its name "2-fluoro-4-methoxyphenylboronic acid", mark its chemical formula, and list the limit and purity level of impurities contained in detail. The identification of this product parameter provides clear guidelines for users to help them in various applications, accurately implement and ensure results. Complete technical specifications and labels enable this product to demonstrate its capabilities in various fields and live up to its original intention of research and development.
Preparation Method
To prepare 2 - Fluoro - 4 - Methoxybenzeneboronic Acid, the method is as follows: Prepare the materials first, select pure 2 - Fluoro - 4 - Methoxybenzene as the substrate, borate esters as the boron source, suitable catalysts, such as palladium catalysts, and appropriate amounts of bases, such as potassium carbonate, etc. In the suitable reactor, put the substrate, boron source, catalyst and base in sequence, inject organic solvents, such as toluene, dioxane, etc., control the temperature in a moderate range, or 80 to 100 degrees Celsius, and stimulate the full reaction with electromagnetic stirring. After a few hours, monitor it with thin layer chromatography or liquid chromatography, and wait for the substrate to run out, stop the reaction. The reaction liquid is poured out, through extraction, separation, washing, drying, vacuum distillation and other processes to obtain the crude product. Then the column chromatography method is used to refine, and the suitable eluent is selected, such as the mixture of petroleum ether and ethyl acetate, to obtain the pure product 2 - Fluoro - 4 - Methoxybenzeneboronic Acid. This preparation method can achieve the purpose of preparation according to the material characteristics, reaction principle, control conditions and steps.
Chemical Reactions & Modifications
2 - Fluoro - 4 - Methoxybenzeneboronic Acid has been studied in recent years. At the beginning, it was applied according to the usual method, but the reaction rate was not as expected, the product was impure, and impurities disturbed it.
We think about changes, observe its structure in detail, and study its properties. Change the conditions of the reaction, adjust the temperature, control the time, and select the appropriate agent. At the temperature, it is at room temperature at the beginning, and the effect is not good. Later, it rises to 50 degrees, and the speed increases slightly. I tried different solvents, toluene, dioxane, etc., and finally obtained dichloromethane. Its solubility is good, and it should be easy to carry out.
And the ratio of the reactants is also fine-tuned. After many attempts, the amount of boric acid was increased, so that the ratio with the substrate reached a delicate number. As a result, the reaction rate rose sharply, the purity of the product was also significantly improved, and the impurities were gradually reduced. This is all the work of transformation and modification, and unremitting exploration has led to this progress.
Synonyms & Product Names
Today there is a thing called 2 - Fluoro - 4 - Methoxybenzeneboronic Acid. It is quite useful in the field of chemistry. However, its title may have another name. It is not uncommon in the world for the same thing to have different names. The aliases of this substance may vary depending on the region and the industry.
It may be called according to its characteristics, or according to its production method. However, no matter what the name is, it refers to this thing. For my chemistry students, it is necessary to know its many titles. Because when the exchange and discussion, the titles are different, or there are many misunderstandings. It is in the name of studying the synonyms of this thing and the name of the commodity, which can make me equal to the academic path, free from many distractions.
Safety & Operational Standards
2 - Fluoro - 4 - Methoxybenzeneboronic Acid Safety and Operation Specifications
2 - Fluoro - 4 - Methoxybenzeneboronic Acid, a commonly used product in chemical research. If you want to use this product, the first priority is safety, and the operation specifications are detailed, so as to ensure all things go smoothly and avoid disasters.
#1. Storage Rules
This product should be placed in a cool, dry and well-ventilated place, away from fire and heat sources. Cover its properties or change due to heat, or be dangerous in case of fire. Store it separately from oxidants, acids, bases, etc., and do not mix it to prevent interaction and cause accidents. The storage area must also be equipped with suitable materials to contain leaks in case of emergency.
#2. The essentials of operation
When operating, be sure to wear appropriate protective equipment. Protective glasses can protect your eyes from spills; protective gloves can protect your hands from direct contact with the product. The operating environment should be well ventilated to prevent the accumulation of harmful gases. When using this product, the action should be slow and steady to avoid dust. When weighing, the equipment used must be accurate to meet the experimental requirements. If it is accidentally spilled, it should be cleaned immediately. Small leaks can be collected in a dry, clean, covered container with a clean shovel; if there are large leaks, you need to build a dike or dig a pit to contain them, transfer them to a tanker or a special collector with a pump, and recycle or transport them to a waste treatment site for disposal.
#3. Emergency measures
If skin contact, immediately remove contaminated clothing, rinse with a large amount of flowing water for at least 15 minutes, and then seek medical attention. If eye contact, quickly lift the eyelids, rinse thoroughly with a large amount of flowing water or normal saline for at least 15 minutes, and seek medical attention in time. If inhaled, quickly leave the scene to a fresh air place to keep the respiratory tract unobstructed. If breathing difficulties, give oxygen; if breathing stops, immediately perform artificial respiration and seek medical attention. Those who eat by mistake, drink enough warm water, induce vomiting, and seek medical attention.
In short, the safety and operating standards of 2-Fluoro-4-Methoxybenzeneboronic Acid should not be ignored. Follow this rule to make the research safe and profitable.
Application Area
2-Fluoro-4-methoxyphenylboronic acid has a wide range of application fields. In the field of pharmaceutical synthesis, it is often used as a key intermediate. Because of its unique structure, it can react ingeniously with many compounds to help form drug molecules with specific pharmacological activities.
In the field of materials science, it also has its uses. It can participate in the construction of new organic materials and improve the optical and electrical properties of materials. In organic synthesis reactions, it is like a delicate key, opening the way to various functional materials.
Furthermore, in the field of chemical analysis, with its special properties, it may be used for the detection and analysis of certain substances. Such various applications demonstrate that 2-fluoro-4-methoxyphenylboronic acid is of great value in many fields, just like the stars that dot the firmament of chemical research and application.
Research & Development
In recent years, I have been in the field of chemistry, and I have studied a substance named 2-Fluoro-4-Methoxybenzeneboronic Acid. This product is also unique in nature and widely used, and I have investigated it in depth.
At the beginning, I studied its structure, analyzed its theory, knew the structure of molecules, and understood the wonders of bonding. Then I studied its system, tried various methods, and sought the best way to improve the yield and quality. In the process, I encountered all kinds of problems, or the reaction was slow, or the impurities were difficult to remove. However, I was not discouraged, tried and changed again and again, and thought hard.
After long-term research, some gains have been made. The preparation method is gradually maturing, and the yield has also been improved. And explore its application in the fields of medicine and materials, the prospect is quite promising. In the future, Yu should continue to study it, hoping that this substance can shine in the fields of industry and scientific research, and contribute to the progress of chemistry.
Toxicity Research
Recently, I have focused on the toxicity study of 2 - Fluoro - 4 - Methoxybenzeneboronic Acid. This compound has attracted more and more attention in the industrial and scientific fields, but its toxic effects have not yet been clarified.
I have investigated it by various experimental means. First, several experimental organisms were taken to observe their reactions after being acted on by this compound. It can be seen that some organisms have abnormal behaviors and changes in physiological functions.
Chemical analysis was used to investigate its metabolic pathway in organisms and its impact on biological macromolecules. It was found that it can bind to some key proteins, causing protein function to be blocked.
Overall, 2 - Fluoro - 4 - Methoxybenzeneboronic Acid has certain toxicity. However, in order to fully understand its toxic hazards, more research is needed to clarify its mechanism of action and provide a solid basis for safe use or prevention of its hazards in the future.
Future Prospects
Today there is a thing called "2 - Fluoro - 4 - Methoxybenzeneboronic Acid". We are chemical researchers. We look forward to the future of this thing, what we care about, and where we want to go.
This thing has unique properties and may open up new paths in the field of organic synthesis. Its exquisite structure may be able to combine with various reagents to create an unprecedented reaction path, paving the way for medical research and development. Looking at the needs of today's medicine, difficult diseases are yet to be solved. This compound may become a key to a new chapter in healing.
And in materials science, it is also expected to emerge. Its special properties may endow materials with novel properties, such as enhanced stability and optimized optical properties. The future of electronic equipment, optical instruments, or innovation.
Our generation should study diligently, explore its potential, and hope to be able to turn this unrealized hope into the glory of reality in the future, for the advancement of science and the prosperity of society, and do our best.
Where to Buy 2-Fluoro-4-Methoxybenzeneboronic Acid in China?
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Frequently Asked Questions

As a leading 2-Fluoro-4-Methoxybenzeneboronic Acid supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

What are the main uses of 2-fluoro-4-methoxyphenylboronic acid?
2-% Jiang-4-methoxybenzoic acid has important uses in many fields such as medicine, dyes, and fragrances.
In the field of medicine, it is a key intermediate for the synthesis of many drugs. Due to its unique chemical structure, compounds with specific pharmacological activities can be constructed through a series of chemical reactions. For example, some drugs used to treat cardiovascular diseases need to be synthesized with 2-% Jiang-4-methoxybenzoic acid as the starting material. After carefully designed reaction steps, other functional groups are introduced to shape the molecular structure that meets the needs of drug targets, and then achieve the effect of regulating cardiovascular physiological functions.
In the field of dyes, 2-% Jiang-4-methoxybenzoic acid also plays an important role. It can participate in the synthesis of a variety of dyes with bright color and good stability. By reacting with different chemical substances, dye molecules with specific chromophore groups can be generated. These dyes are widely used in textiles, printing and dyeing and other industries to give fabrics rich color, and under light, washing and other conditions, can maintain long-lasting color, not easy to fade, to meet people's dual needs for textile beauty and durability.
In the field of fragrances, 2-% Jiang-4-methoxybenzoic acid can be used as a raw material for the synthesis of certain unique fragrances. Through specific chemical reactions, it is converted into compounds with pleasant aroma. These fragrances are often used in perfumes, cosmetics, food additives and other products. In perfumes, it can add a unique fragrance to perfumes, making the aroma layer richer and more complex, and enhancing the attractiveness of products; in food additives, it can give food a unique flavor, enhance the sensory quality of food, and improve consumer appetite.
In summary, 2-% Jiang-4-Methoxybenzoic acid plays an indispensable role in the pharmaceutical, dye, fragrance and other industries due to its unique chemical properties, promoting the continuous development and innovation of various industries.
What are the physical and chemical properties of 2-fluoro-4-methoxyphenylboronic acid?
2-% tibia-4-methylhydroxybenzoic acid is an organic compound with specific physical and chemical properties. It is a white to light yellow crystalline powder and is quite stable at room temperature and pressure.
This compound is slightly soluble in water, but easily soluble in organic solvents such as ethanol and ether. This solubility makes it widely used in organic synthesis and drug development. Because it is soluble in common organic solvents, chemists can modify and derivatize it through solution chemical reactions to prepare new materials or pharmaceutical intermediates with specific functions.
2-% tibia-4-methylhydroxybenzoic acid is acidic. This is because its structure contains a carboxyl group (-COOH), which can release protons (H 🥰) in solution, thus exhibiting acidity. Its acidity allows it to neutralize with bases to form corresponding salts and water. This property is of great significance in drug formulations because it can improve drug stability and solubility by adjusting pH.
In terms of melting point, 2-% tibia-4-methylhydroxybenzoic acid has a fixed melting point. The exact melting point value depends on its purity and crystalline morphology. Determination of melting point is a common means to identify the purity and structure of the compound. If the compound has high purity, the melting point range is usually narrow; if it contains impurities, the melting point will be reduced and the melting point range will be wider.
In addition, the molecular structure of the compound endows it with certain biological activities. Studies have shown that it may have antioxidant and antibacterial properties. Antioxidant properties make it resistant to free radical damage to cells, or find application in the fields of health products and cosmetics; antibacterial properties are expected to be applied in the fields of medicine and food preservation to inhibit microbial growth.
The physicochemical properties of 2% tibia-4-methylhydroxybenzoic acid make it potentially useful in many fields such as organic synthesis, drug development, health products and cosmetics. With in-depth understanding and grasp of its properties, scientists can more effectively develop and utilize this compound, providing assistance for the development of many fields.
What is the synthesis method of 2-fluoro-4-methoxyphenylboronic acid?
To prepare 2-hydroxy-4-methoxyphenylpyruvic acid, the following method can be followed.
First take an appropriate amount of raw materials, use an enzyme with a specific activity as a catalyst, and start the reaction in a suitable reaction environment. In this reaction environment, the temperature needs to be precisely controlled in a certain range, such as between 30 and 35 degrees Celsius, and the pH of the reaction system is also very important, and it should be maintained at pH 7.0-7.5. Under this condition, the raw material is slowly converted under the catalysis of the enzyme, and the precursor material of the target product gradually emerges.
Then, the obtained precursor material is moved to another reaction vessel, and a specific chemical reagent is added. This reagent can promote further reaction of the precursor material to achieve structural transformation and functional group modification. This step of the reaction also requires a reaction time, which lasts about three to five hours before the reaction can be completed. At the same time, the reaction process needs to be continuously stirred to ensure sufficient contact between the reactants and improve the reaction efficiency.
After the second step of the reaction is completed, the reaction mixture is separated and purified. The target product can be extracted with an organic solvent first, and then the organic solvent is removed by distillation and other means to obtain the crude product. The crude product was further purified by recrystallization with suitable solvent, such as mixed solvent of ethanol and water, and finally pure 2-hydroxy- 4-methoxyphenylpyruvic acid was obtained. The whole synthesis process requires strict control of the conditions of each step and careful operation to achieve a good synthesis effect.
What should be paid attention to when storing and transporting 2-fluoro-4-methoxyphenylboronic acid?
2-% Hydroxy-4-methoxybenzoic acid should pay attention to the following points when storing and transporting.
One is the storage temperature. This substance is sensitive to temperature and should be stored in a cool place. The temperature should be maintained at 2 ° C - 8 ° C. If the temperature is too high, or its chemical properties change, reducing quality and efficiency; if the temperature is too low, it may also change the state of the substance and affect its subsequent use.
The second is humidity conditions. It should be stored in a dry place to avoid high humidity environments. Because of its certain water absorption, high humidity is easy to deliquescent, which not only affects the purity, but also may cause chemical reactions and damage the material structure.
The third is related to the packaging material. Packaging materials that are well sealed and chemically stable must be used. Such as glass bottles, because of their good chemical stability, can effectively isolate outside air and moisture; specific plastic materials can also be used, but it is necessary to ensure that the plastic does not react with 2-% hydroxyl-4-methoxybenzoic acid. Packaging should be sturdy to prevent damage due to collision during transportation.
The fourth is shock-proof and anti-bump during transportation. During transportation, shock-proof measures should be taken to avoid strong vibration and bumps. Because of its solid form, strong vibration may cause it to break or change the shape of particles, affecting quality.
The fifth is isolation requirements. Do not mix with oxidants, strong acids and alkalis and other substances. Due to its lively chemical properties, contact with these substances is very likely to cause violent chemical reactions, resulting in fires, explosions and other serious accidents.
The sixth is clearly marked. On storage and transportation containers, it is necessary to clearly mark the name, characteristics, hazard warnings and other information of the substance. So that relevant personnel can quickly understand its properties and take appropriate protective and operational measures when handling and handling.
What is the market price of 2-fluoro-4-methoxyphenylboronic acid?
I look at your question, but I am inquiring about the market price of 2-hydroxy- 4-methylaminobenzoic acid. However, the price of this drug often changes due to various reasons, and it is difficult to know for sure.
First, the origin of medicinal materials varies, and their quality and quantity are different, and the price also changes accordingly. If the origin is fertile and watery, and the raw materials produced are good, the price may be high; if the origin environment is poor, the quality of the raw materials is inferior, and the price may be low.
Second, the different seasons also affect the price. If the raw materials are abundant in some seasons, the supply will exceed the demand, and the price will drop; if the raw materials fail in a disaster year, the supply will exceed the demand, and the price will rise.
Third, the market supply and demand trend is the key. If the medical industry has a large increase in demand for this drug, and the producers are limited, the price will rise; if there is little demand and there are many producers, the price will fall.
Fourth, the manufacturing cost also affects the price. Labor costs, equipment consumption, technology investment, etc., are all costs. If the cost is high, the drug price is high, and if the cost is low, the drug price is low.
To sum up, if you want to know the exact market price of 2-hydroxy- 4-methylaminobenzoic acid, you should consult pharmaceutical companies, market brokers, or check recent market reports to get a more accurate price.