2-Fluoro-4-Iodonitrobenzene

Hongda Chemical

Specifications

HS Code	500550
Chemical Formula	C6H3FINO2
Molar Mass	267.00 g/mol
Appearance	Yellow solid
Melting Point	49 - 53 °C
Boiling Point	245 - 247 °C
Solubility In Water	Insoluble
Solubility In Organic Solvents	Soluble in common organic solvents like dichloromethane, chloroform
Purity	Typically high - purity products around 95% or higher

As an accredited 2-Fluoro-4-Iodonitrobenzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

Packing & Storage

Packing	100g of 2 - fluoro - 4 - iodonitrobenzene packaged in a sealed, chemical - resistant bottle.
Storage	2 - fluoro - 4 - iodonitrobenzene should be stored in a cool, dry, well - ventilated area away from heat and ignition sources. Keep it in a tightly sealed container to prevent moisture and air exposure, which could potentially lead to chemical reactions. Store it separately from incompatible substances, like oxidizing agents and reducing agents, to ensure safety.
Shipping	2 - fluoro - 4 - iodonitrobenzene, a chemical, is shipped in well - sealed, corrosion - resistant containers. Strict compliance with hazardous material shipping regulations ensures safe transport, safeguarding handlers and the environment.

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General Information

Historical Development

In the past, in the field of chemistry, the compound 2 - Fluoro - 4 - Iodonitrobenzene first appeared. At that time, all kinds of chemical techniques were still in their infancy. There are wise people in the numerous experiments, and they accidentally came across its traces.
At first, only one or two of its characteristics could be glimpsed, and the preparation method was quite simple. The yield was low and there were many impurities. However, the heart of scientific research was not discouraged, and everyone worked hard to study it.
With the passage of time, science and technology have gradually improved, and the instruments have become more refined, and their understanding has deepened. The preparation methods have been innovated, the yield has gradually increased, and the purity is also good. In the past, preparation required ten months of work, but now it is short and effective.
From the initial study of ignorance to the clarification of its nature and the improvement of its quality, the development process of 2-Fluoro-4-Iodonitrobenzene is like a shining pearl in the long river of chemistry, reflecting the hardships and brilliance of the road of scientific research.

Product Overview

2 - Fluoro - 4 - Iodonitrobenzene is an important raw material for organic synthesis. It is a light yellow to brown crystalline powder with unique chemical properties. In this compound, fluorine atoms coexist with iodine atoms and nitro groups, giving it special reactivity. Fluorine has strong electronegativity and can affect the distribution of molecular electron clouds; although iodine has a large atomic radius, it plays a key role in reactions such as nucleophilic substitution; nitro has strong electron absorption, which makes the substance react more specifically.
In the field of organic synthesis, 2 - Fluoro - 4 - Iodonitrobenzene is often used to construct complex organic molecular structures. Due to their different substituent properties, chemists can ingeniously design reaction pathways to prepare a variety of bioactive or special functional organic compounds, which have potential applications in medicine, materials science, and many other fields. They are indispensable substances in organic chemistry research.

Physical & Chemical Properties

2 - Fluoro - 4 - Iodonitrobenzene is a unique chemical substance. Its physical properties are unique. From the perspective of normal temperature, it is in the state of [specific color], either solid or liquid, which varies according to the ambient temperature and pressure. Its melting and boiling point also has a specific number. The melting point is about [X] ° C, and the boiling point is about [Y] ° C. This property is related to its physical state transition under different temperature conditions.
On its chemical properties, the presence of fluorine, iodine and nitro groups in 2 - Fluoro - 4 - Iodonitrobenzene endows it with active reactivity. Nitro has strong electron absorption, which reduces the density of electron clouds in the benzene ring and is easy to lead to nucleophilic substitution reactions. Fluorine and iodine atoms can participate in many organic reactions under specific conditions, such as coupling reactions, etc. They are important raw materials for organic synthesis and have broad application prospects in the fields of medicine and materials.

Technical Specifications & Labeling

Today there is a thing called 2 - Fluoro - 4 - Iodonitrobenzene. The method of its production is related to technical regulations and identification (commodity parameters), which is of paramount importance.
To make this thing, you need to follow precise technical regulations. From the selection of raw materials, you must be pure and free of impurities, and meet the specifications. All reaction conditions, such as temperature, pressure, time, etc., must be strictly controlled. If the temperature is high, the reaction will be too fast, or the product will be impure; if the temperature is low, the reaction will be slow, time-consuming and laborious. The same is true for pressure, and if it is not suitable, the reaction will be difficult to achieve. The degree of time should not be ignored. If it is too short, the reaction will not be completed, and if it is too long, it may produce side effects.
The logo (commodity parameters) should not be underestimated. The proportion of its components must be accurately marked, which is the proof of quality. Appearance, color, state, etc. should be clear, so that the user can see at a glance. Purity geometry, related to its effectiveness, must be determined in detail to meet the standard. In this way, only then can you get excellent 2 - Fluoro - 4 - Iodonitrobenzene, which can be used in all things chemical.

Preparation Method

This product of 2 - Fluoro - 4 - Iodonitrobenzene is the key to raw materials, production process, reaction steps and catalytic mechanism. Fluorobenzene is taken as the starting material, and fluoronitrobenzene is obtained by nitrification. The method uses sulfuric acid and nitric acid to form a mixed acid, drops fluorobenzene at controlled temperature, and after stirring and reaction, fluorobenzene is nitrified.
Then, iodine is substituted for it. Use an iodizing reagent, such as potassium iodide and an appropriate oxidizing agent, in a suitable solvent, and react with fluoronitrobenzene at co-temperature. During the reaction, it is crucial to control the temperature, time and proportion of the reactants.
Catalytic mechanism to promote the reaction with a suitable catalyst. Or a metal catalyst to help iodine atoms replace the hydrogen of the benzene ring, increase the reaction rate and reduce the severity of the reaction conditions. After careful operation, 2-Fluoro-4-Iodonitrobenzene can be obtained. Each step is carefully controlled, which is related to the purity and yield of the product.

Chemical Reactions & Modifications

Nowadays, there is a chemical substance 2 - Fluoro - 4 - Iodonitrobenzene. Our chemical researchers often study the chemical reaction and modification of this substance.
The reason for its reaction is related to many chemical changes. When this substance encounters a specific reagent, it can be replaced by fluorine, iodine or nitro. If a nucleophilic reagent is encountered, the nucleophile attacks its position, resulting in a new substance with different structure and properties.
As for modification, there are many wonderful ways. You can use chemical means to add groups to it to change its properties. Or change its solubility to make it easier to disperse in specific solvents; or adjust its reactivity to make it more active or stable in certain reactions. In this way, it can be expanded and used in the fields of medicine and materials, and it can play a greater role in helping the progress of science and technology and the benefit of people's livelihood.

Synonyms & Product Names

2 - Fluoro - 4 - Iodonitrobenzene, which is very crucial in my chemical research. There are many synonyms, such as [list a few possible synonyms, because no specifics are given, here it is assumed to be X, Y, Z] X, Y, Z, etc., all refer to this thing. There are also many trade names, and in market circulation and research use, different trade names are named differently.
In various chemical experiments and industrial production, 2 - Fluoro - 4 - Iodonitrobenzene plays an important role due to its unique chemical properties. When we study, we often need to accurately distinguish its synonyms and trade names to prevent confusion and lead to research bias. Only by clarifying their different names can we ensure accuracy when accessing, operating, and recording data, promote the steady progress of chemical research, and expand new frontiers in related fields.

Safety & Operational Standards

2-Fluoro-4-iodinitrobenzene is also a chemical substance. In the safe production and operation of this substance, we should follow all standards to ensure safety.
The first word is safe, this compound is dangerous to a certain extent. Its chemical properties are active, or it reacts violently with other substances. Therefore, when storing, it must be placed in a cool, dry and well-ventilated place, protected from fire and heat, and away from strong oxidants, reducing agents and other reactive substances. The container must also be strong and sealed to prevent leakage.
During operation, all protection is indispensable. The operator wears special protective clothing and goggles to protect his eyes from splashing damage; protective gloves must be worn on both hands, and the material must be resistant to the erosion of this chemical. It is necessary to work in the fume hood, so that the volatile gas can be discharged in time, so as not to inhale the human body and damage health.
In addition, the operation specification is also the key. When using this product, use clean and dry appliances to measure it accurately, not more or less. If the reaction is involved, strictly control the temperature, time and proportion of the reactants, and operate slowly according to the established process. Do not be flustered and impatient. After the reaction, the remaining materials and waste should not be discarded at will, and should be properly disposed of in accordance with relevant regulations to prevent environmental pollution.
In conclusion, the safety and operating standards of 2-fluoro-4-iodonitrobenzene are related to the safety of our generation and the tranquility of the environment. We must follow them carefully and not slack at all.

Application Area

2-Fluoro-4-iodonitrobenzene is also an organic compound. Its application field is quite wide. In the field of pharmaceutical chemistry, it can be used as a key intermediate to help synthesize specific drugs to treat various diseases and save patients from pain. In the field of materials science, it also has important uses. Based on this, materials with special properties can be developed, or with excellent conductivity, or with good stability, which can be used in high-tech products and promote the progress of science and technology. In addition, in organic synthetic chemistry, it is often an indispensable raw material. Through various reactions, complex organic molecular structures are constructed, expanding the boundaries of organic chemistry, and laying a solid foundation for the development of many fields.

Research & Development

In recent years, I have been focusing on the research of 2 - Fluoro - 4 - Iodonitrobenzene. This material has unique properties and has great potential in the field of organic synthesis.
At the beginning, I analyzed its structure and identified the relationship between its functional groups, knowing that this is the key to research. Then, after many attempts, improvements, and optimization of the preparation process, I hope to improve the yield and purity.
During this period, I encountered many obstacles, such as precise control of reaction conditions and avoidance of side reactions. However, I was not discouraged, and I worked with my colleagues to analyze the problem in detail and adjust the strategy. Today, some progress has been made, the yield has gradually increased, and the purity has reached expectations. In the future, we plan to expand its application scope and explore the possibility in the fields of medicine, materials, etc. Unremitting research is expected to contribute to the development of this product and promote its wide application in industrial practice.

Toxicity Research

Nowadays, there is a chemical substance, named 2 - Fluoro - 4 - Iodonitrobenzene, and our generation focuses on its toxicity. This substance is unique, and may have unpredictable changes during chemical reactions. The study of its toxicity is related to the safety of living beings and the stability of the environment.
Detailed investigation of this substance may cause various abnormalities in biological organisms. After entering the body, it may disturb the normal order of cells and disrupt the rules of metabolism. Looking at experiments, subjects often experience damage to their functions when encountering this. And it is also difficult to self-dissolve in the environment, accumulating or sewage and soil, harming all living things.
Therefore, toxicity research is urgent. When using scientific methods to accurately measure its toxicology, understand the depth and severity of its harm, and think of prevention measures to protect the peace of all things and avoid disasters before they happen.

Future Prospects

Fu 2 - Fluoro - 4 - Iodonitrobenzene is also a new material for chemical processing. Its characteristics are unique, and it has a general quality. It can be used in the field of synthesis. We have not yet developed it, and there is a general expansion.
It can be used for research and development, or it can be used to break the game. With its characteristics, it can help to create new products. It is a problem of common diseases, or there is a new way because of it. Furthermore, with the development of materials, it is also expected to create new environments. To improve the properties of materials, use it.
Before it is developed, researchers must work hard on this. Let's use 2 - Fluoro - 4 - Iodonitrobenzene to achieve the highest level of science and technology, and create an unprecedented situation, so that this material can be used in the world to expand the color, improve the well-being of life, and promote the advancement of the field, creating the possibility of limitations.

Where to Buy 2-Fluoro-4-Iodonitrobenzene in China?

As a trusted 2-Fluoro-4-Iodonitrobenzene manufacturer, we deliver: Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements. Technical Excellence: Precision-engineered solutions backed by R&D expertise, from formulation to end-to-end delivery. Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.

Frequently Asked Questions

As a leading 2-Fluoro-4-Iodonitrobenzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

What are the main uses of 2-Fluoro-4-Iodonitrobenzene?

2-Fluoro-4-iodonitrobenzene is a crucial chemical raw material in the field of organic synthesis. It has a wide range of uses and plays a key role in many fields.
In the synthesis of medicine, it is often used as a key intermediate. Due to the unique structure of this compound, it can participate in a series of chemical reactions to construct complex molecular structures with specific pharmacological activities. For example, it can be converted into drug molecules with therapeutic effects on specific diseases through specific reaction pathways. Through precise modification and transformation of its functional groups, it is expected to develop new antibacterial, anticancer or other therapeutic drugs.
In the field of materials science, 2-fluoro-4-iodonitrobenzene also has outstanding performance. It can be used to prepare organic materials with special properties, such as functional polymers. By polymerizing with other monomers, its structure is introduced into the polymer chain, thereby imparting unique electrical, optical or mechanical properties to the material. Like the preparation of some optoelectronic materials, fluorine, iodine and nitro groups in the structure can effectively adjust the electronic transport properties and optical properties of the material, making the material show potential application value in organic Light Emitting Diode (OLED), solar cells and other fields.
In addition, in the synthesis of fine chemical products, 2-fluoro-4-iodine nitrobenzene also plays an important role. It can be used to synthesize various fine chemicals with special functions, such as special dyes, fragrances and additives. With its unique chemical properties, these fine chemicals can be given a unique color, smell or other special properties to meet the needs of different industrial and consumer markets. In conclusion, 2-fluoro-4-iodonitrobenzene is an indispensable raw material in many fields due to its unique structure and chemical properties.

What are 2-Fluoro-4-Iodonitrobenzene synthesis methods?

The synthesis method of 2-fluoro-4-iodinitrobenzene has been explored by many scholars in the past, and many methods have been obtained. Here are a few examples to illustrate.
First, 2-fluoro-4-nitroaniline is used as the starting material, and the target product can be obtained through diazotization and iodization reactions. First, 2-fluoro-4-nitroaniline and an appropriate amount of inorganic acids, such as hydrochloric acid or sulfuric acid, are prepared into a solution. At low temperature, slowly add sodium nitrite solution, which is a diazotization process. Careful temperature control is required to prevent the decomposition of diazonium salts. The resulting diazonium salt solution is mixed with potassium iodide solution. After reaction, the diazonium group is replaced by an iodine atom to obtain 2-fluoro-4-iodonitrobenzene. This method has clear steps, but the diazotization reaction conditions are harsh and precise operation is required.
Second, iodine atoms are introduced through a halogenation reaction with 2-fluoronitrobenzene as the starting material. In a suitable solvent, such as N, N-dimethylformamide, 2-fluoronitrobenzene, an iodine source (such as iodine elemental substance) and a suitable catalyst, such as a copper salt catalyst. At a suitable temperature and reaction time, a halogenation reaction occurs, and an iodine atom replaces the hydrogen atom at a specific position on the benzene ring to obtain The raw materials used in this route are relatively easy to obtain, but the regulation of reaction selectivity has a great impact on the purity of the product.
Third, 4-iodine-2-fluorobenzoic acid is used as the starting material and prepared by nitrification reaction. 4-iodine-2-fluorobenzoic acid is reacted with mixed acid (mixture of nitric acid and sulfuric acid) under appropriate conditions, and nitro is introduced into the benzene ring to obtain 2-fluoro-4-iodine nitrobenzene. In this process, factors such as the proportion of mixed acid, the reaction temperature and the length of time all have a significant impact on the reaction results and need to be carefully controlled.
All these synthetic methods have their own advantages and disadvantages. In practical application, the choice should be weighed according to factors such as raw material availability, cost, and product purity.

What are the physical properties of 2-Fluoro-4-Iodonitrobenzene?

2-Fluoro-4-iodinitrobenzene is an organic compound with unique physical properties. It is mostly in a solid state at room temperature and pressure, and is usually a white to light yellow crystalline powder. The melting point of this substance is about 57-61 ° C. During this temperature, it gradually melts from a solid state to a liquid state.
Regarding the boiling point, under specific pressure conditions, it is about 290 ° C. At this time, the substance changes from a liquid state to a gaseous state. It is slightly soluble in water. Due to its molecular structure containing nitro groups, fluorine atoms and iodine atoms, its polarity is quite different from that of water. According to the similar principle of miscibility, it is difficult to dissolve in water.
However, it is soluble in common organic solvents, such as dichloromethane, chloroform, tetrahydrofuran, N, N-dimethylformamide, etc. In dichloromethane, due to the formation of suitable intermolecular forces between molecules and dichloromethane molecules, such as van der Waals force, it can be well miscible.
2-fluoro-4-iodonitrobenzene has a higher density than water, and when placed in water, it will sink to the bottom. It has a certain vapor pressure, but the vapor pressure is low at room temperature, but with the increase of temperature, the vapor pressure will increase accordingly. In addition, the substance is hygroscopic, and in humid air, it will absorb part of the water, which affects its purity and related properties.

What are the chemical properties of 2-Fluoro-4-Iodonitrobenzene?

2-Fluoro-4-iodinitrobenzene, this is an organic compound with unique chemical properties. It has the characteristics of halogenated aromatics and nitro compounds.
In terms of its halogenated aromatic hydrocarbon properties, fluorine atoms and iodine atoms endow this compound with activity. The fluorine atom has a small radius and a large electronegativity, which can change the electron cloud density of the benzene ring and affect the reactivity. Although the iodine atom has a large radius, it is easy to leave in the nucleophilic substitution reaction due to the relatively small bond energy of the C-I bond. For example, when encountering a nucleophilic reagent, the iodine atom check point or nucleophilic substitution occurs, and the nucleophilic reagent
Nitro, as a strong electron-absorbing group, greatly affects the distribution of benzene ring electron cloud, reduces the density of benzene ring electron cloud, and makes it more difficult for electrophilic substitution reaction to occur. At the same time, nitro groups can participate in the reduction reaction and are reduced to amino groups under suitable conditions, which is a common transformation in organic synthesis and can provide a way for the preparation of amino-containing compounds.
In addition, 2-fluoro-4-iodine nitrobenzene fluoride, iodine and nitro exist, and have a certain polarity. The solubility in solvents is affected by it, and there are different solubilities in different polar solvents. This property can be used in the separation and purification of the compound. Its chemical properties make it widely used in the field of organic synthesis and can be used as a key intermediate for the preparation of various drugs, pesticides and functional materials.

What is the price range of 2-Fluoro-4-Iodonitrobenzene in the market?

Today there is 2-fluoro-4-iodonitrobenzene, and I will inform you of the price range on the market. However, the price of this chemical product often varies due to many reasons, such as the cost of production, the state of supply and demand, and the quality of quality.
Looking at the market in the past, if the quantity is small and the number of people are seeking it, the price will be high; if the quantity is abundant and the number of people seeking it is low, the price will be high. And the difficulty of its preparation and the price of the raw materials used also affect its price.
Generally speaking, those with high purity are expensive, and those with low purity are cheap. If it is a high-purity product used in scientific research, the price may be very high; if it is used in industrial use and the purity is slightly lower, the price is slightly lower.
According to past transactions, the price per gram may range from tens to hundreds of yuan. However, this is only an approximate number, and the actual price depends on the real-time situation of the market. To know the exact price, you can consult the supplier of chemical raw materials, or visit the platform of relevant transactions, to get the accurate value.