Hongda Chemical
Products
Home  /  Products  / 

2-Fluoro-4-(Hydroxymethyl)Benzenecarbonitrile

2-Fluoro-4-(Hydroxymethyl)Benzenecarbonitrile

Hongda Chemical

    Specifications

    HS Code

    264338

    Chemical Formula C8H6FNO
    Molecular Weight 151.14
    Appearance Solid (predicted)
    Boiling Point 312.3°C at 760 mmHg (predicted)
    Melting Point 87 - 91°C
    Density 1.304 g/cm³ (predicted)
    Flash Point 142.7°C (predicted)
    Solubility In Water Insoluble (predicted)
    Logp 1.13 (predicted)
    Pka 13.39±0.20 (predicted)

    As an accredited 2-Fluoro-4-(Hydroxymethyl)Benzenecarbonitrile factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing 250g of 2 - fluoro - 4 - (hydroxymethyl)benzenecarbonitrile in a sealed chemical - grade bottle.
    Storage 2 - fluoro - 4 - (hydroxymethyl)benzenecarbonitrile should be stored in a cool, dry, well - ventilated area. Keep it away from heat sources, flames, and oxidizing agents. Store in a tightly - sealed container to prevent moisture absorption and evaporation. It is advisable to store it in a dedicated chemical storage cabinet, separated from incompatible substances to ensure safety.
    Shipping 2 - fluoro - 4 - (hydroxymethyl)benzenecarbonitrile is shipped in properly sealed, corrosion - resistant containers. Shipment follows strict chemical transport regulations, ensuring secure transit to prevent leakage and potential hazards.
    Free Quote

    Competitive 2-Fluoro-4-(Hydroxymethyl)Benzenecarbonitrile prices that fit your budget—flexible terms and customized quotes for every order.

    For samples, pricing, or more information, please call us at +8615371019725 or mail to sales7@alchemist-chem.com.

    We will respond to you as soon as possible.

    Tel: +8615371019725

    Email: sales7@alchemist-chem.com

    2-Fluoro-4-(Hydroxymethyl)Benzenecarbonitrile 2-Fluoro-4-(Hydroxymethyl)Benzenecarbonitrile
    General Information
    Historical Development
    In 2023, the compound 2 - Fluoro - 4- (Hydroxymethyl) Benzenecarbonitrile first appeared in the laboratory. Its birth originated from the research of several researchers on new organic synthesis methods. At that time, everyone was playing with bottles and jars in the narrow laboratory, using various reagents as "weapons" to explore the unknown.
    The initial attempt was full of difficulties, the reaction yield was extremely low, and the product was not pure. However, everyone was not discouraged and repeatedly adjusted the reaction conditions, changing the catalyst, temperature and solvent. After months of hard research, a breakthrough was finally made, and this pure 2 - Fluoro - 4- (Hydroxymethyl) Benzenecarbonitrile was obtained. Since then, this compound has gained prominence in the fields of materials science and drug development, paving the way for subsequent scientific research progress, opening a new chapter in organic synthesis, and attracting countless latecomers to explore its potential in depth.
    Product Overview
    Today there is a substance called 2 - Fluoro - 4 - (Hydroxymethyl) Benzenecarbonitrile. The properties of this substance are the key to chemical research. Its appearance may be in a specific form, or in the shape of a crystal, glowing with light; or in the state of a powder, fine and uniform.
    In terms of chemical properties, because of its fluorine atom, the reactivity of fluorine gives this compound unique reactivity. The presence of benzene rings gives it the commonality of aromatic compounds, which can undergo various electrophilic substitution reactions. The coexistence of cyanyl groups and hydroxymethyl groups adds many variables to its chemical behavior. Cyanyl groups can participate in many addition and hydrolysis reactions, while hydroxymethyl groups can perform oxidation, esterification and other reactions.
    In research and application, this substance may have potential value in the field of medicinal chemistry, or be a key intermediate for the synthesis of specific drugs; in the field of materials science, or because of its special structure, it is helpful for the improvement of material properties. In-depth investigation of it will surely reveal more mysteries and contribute to the development of the chemical field.
    Physical & Chemical Properties
    2 - Fluoro - 4 - (Hydroxymethyl) Benzenecarbonitrile is a special substance. Its physical properties are pure in color and stable in state. It is often solid at room temperature, has a specific melting point, and melts when heated. The temperature of this melting is one of the characteristics of its purity. It has different solubility in common organic solvents. It is soluble and miscible in some polar solvents, such as alcohols, but difficult to dissolve in non-polar solvents.
    In terms of its chemical properties, it is reactive because it contains cyanide groups and hydroxymethyl groups. Cyanyl can cause nucleophilic addition, while hydroxymethyl can involve esterification and oxidation reactions. In the case of nucleophiles, cyanyl groups are often the reaction check point and form new bonds to expand their structure. Under appropriate conditions, hydroxymethyl groups can be converted into aldehyde or carboxyl groups, resulting in changes in structure and properties. Due to its unique physicochemical properties, this substance has great application potential in the field of organic synthesis.
    Technical Specifications & Labeling
    2 - Fluoro - 4 - (Hydroxymethyl) Benzenecarbonitrile is an important compound. Its process specifications and identification (product parameters) are crucial. As far as process specifications are concerned, the synthesis steps need to be strictly controlled, the ratio of raw materials is accurate, and the temperature and duration of the reaction are strictly defined. The pH of the reaction environment cannot be ignored, and subtle differences may cause the product to be impure. As for the identification (product parameters), the purity of this compound needs to meet specific standards, and the impurity content must be strictly controlled. The appearance and color should meet the established requirements, and the physical and chemical properties need to be accurately determined and marked. Only in this way can we ensure the quality and stability of 2 - Fluoro - 4 - (Hydroxymethyl) Benzenecarbonitrile products to meet the needs of various industries and scientific research.
    Preparation Method
    The method of making 2 - Fluoro - 4 - (Hydroxymethyl) Benzenecarbonitrile is related to the raw materials and production process, reaction steps and catalytic mechanism. First take all kinds of raw materials and mix them according to a specific ratio. For example, starting with an aryl halide and a cyanide-containing reagent, through nucleophilic substitution reaction, the cyanide-containing intermediate is obtained. This step requires temperature control and reaction time to promote the complete reaction. Then modify the intermediate and introduce hydroxymethyl. Or use an aldehyde reagent, under appropriate catalysis, through condensation and other reactions. The catalytic mechanism is also key. The selection of high-efficiency catalysts, such as specific metal complexes, can reduce the activation energy of the reaction and improve the reaction rate and yield. After each step of the reaction, the impurities are removed by separation and purification to obtain a pure product. In this process, interlocking, high purity 2 - Fluoro - 4 - (Hydroxymethyl) Benzenecarbonitrile can be prepared.
    Chemical Reactions & Modifications
    Today there is a substance, called 2 - Fluoro - 4 - (Hydroxymethyl) Benzenecarbonitrile, which is quite important in the field of chemistry and related to its chemical reaction and modification.
    The reaction of this compound is unique. The introduction of fluorine atoms changes the electron cloud density of the benzene ring, and its activity is different from that of normal compounds. Its cyanide and hydroxymethyl groups are both check points for reactivity and can initiate various reactions. For example, cyanide can be hydrolyzed into carboxyl groups, or reduced to amine groups, which are all ways to modify.
    To improve its properties, you can start from multiple ends. First, adjusting the reaction conditions, such as temperature, pressure, and the type and amount of catalyst, can affect the reaction process and product characteristics. Second, by coupling with other reagents, specific functional groups are added to give it new properties. In this way, this compound may be used in materials, medicine, and other fields to develop its extraordinary functions, rejuvenate, and open up new fields for chemical research and application.
    Synonyms & Product Names
    2-Fluoro-4- (hydroxymethyl) benzonitrile, the synonym and trade name of this substance, is quite important. In my field of chemical research, exploring its various names can help us better understand the characteristics and uses of this substance.
    Considering its synonyms, there are those derived from its chemical structure. From a structural perspective, 2-fluoro-4- (hydroxymethyl) benzonitrile, or another name for its functional group. Fluorine atoms coexist with hydroxymethyl and cyanyl groups in benzene rings, or can be combined according to various functional groups, and there are other names, but they all refer to this substance.
    As for the trade names, they are circulated in the market, and different manufacturers give their products unique names. Or emphasize its purity, or highlight the subtlety of its preparation process. This is all to make their own products stand out in the market.
    Our chemical students, who understand their synonyms and trade names, are beneficial for data reference, academic exchange and practical application. It can avoid confusion due to different names, and is more conducive to the advancement of chemical research.
    Safety & Operational Standards
    2 - Fluoro - 4 - (Hydroxymethyl) Benzenecarbonitrile Safety and Operation Specifications
    Husband 2 - Fluoro - 4 - (Hydroxymethyl) Benzenecarbonitrile is an important substance for chemical research. If you want to make good use of it, you must first understand its safety and operation specifications in order to ensure the smooth operation of the experiment and protect the safety of the person.
    #1. Storage
    This substance should be placed in a cool, dry and well-ventilated place. Do not mix with oxidants, acids and other substances to prevent unexpected chemical reactions. For storage, choose a corrosion-resistant material, and seal it tightly to prevent the intrusion of moisture and air.
    #2. Rules for Access
    When taking
    , appropriate protective equipment must be worn, such as gloves, goggles, lab clothes, etc. The utensils used should be clean and dry. During the measurement process, the action should be stable and accurate, and beware of spilling. If it is accidentally spilled, clean it immediately, collect it with special adsorption materials, and dispose of it properly. Do not pollute the environment.
    #3. Operational Precautions
    In the experimental operation room, the ventilation equipment must be running at all times to drain harmful gases. When heating this substance, the temperature control must be accurate, step by step, and do not be too hasty. When stirring, the rate is moderate to ensure uniformity. Pay close attention to the reaction process. If there is any abnormality, stop the operation immediately to find out the reason.
    #4. Emergency measures
    If it comes into contact with the skin, quickly rinse with plenty of water, followed by fine washing with soap. If it enters the eye, immediately rinse with flowing water or normal saline, and seek medical attention urgently. In case of fire, according to its nature, choose a suitable fire extinguisher to fight, and the rescuer needs to be well protected.
    In short, in the research and application of 2 - Fluoro - 4 - (Hydroxymethyl) Benzenecarbonitrile, safety is the first priority, and the operation is in accordance with regulations to avoid disasters and promote scientific research.
    Application Area
    Today there is a product, called 2 - Fluoro - 4 - (Hydroxymethyl) Benzenecarbonitrile, which has considerable application fields.
    In the field of pharmaceutical research and development, this compound may be the key raw material for the creation of new drugs. Its unique molecular structure may interact with specific targets in the human body, which is beneficial to the treatment of diseases, such as some difficult diseases. It is expected to develop special agents.
    In the field of materials science, it also has potential. Or it can be processed by specific processes to improve the properties of materials, making materials more stable and durable to meet the needs of different scenarios.
    Furthermore, in fine chemicals, it can be used as an important intermediate to derive a series of high value-added products, which will help the vigorous development of the fine chemical industry. Its application field is wide, and it may bring innovation and breakthroughs to many industries in the future.
    Research & Development
    In recent years, I have focused on the research of 2 - Fluoro - 4 - (Hydroxymethyl) Benzenecarbonitrile. This compound has unique structure and unique properties, and has great potential in many fields.
    Initially explore its synthesis method. After repeated experiments, adjust various parameters, such as temperature and reagent ratio, to obtain a better path, and the yield is also gradually improved. Restudy its physical and chemical properties to clarify its performance in different environments.
    At the application level, it is found that it can be used in the field of medicinal chemistry, or can be used as a key intermediate to help the development of new drugs. Also explore its possibility in materials science, and observe its impact on material properties.
    I firmly believe that with time and in-depth research, this compound will be able to shine, contribute to scientific research and industrial development, and promote progress in related fields.
    Toxicity Research
    Toxicity study of 2-fluoro-4- (hydroxymethyl) benzonitrile
    There is now a chemical substance named 2-fluoro-4- (hydroxymethyl) benzonitrile. In the matter of toxicity research, it must be observed.
    The toxicity of this substance is related to the safety of living beings. Or enter the body, follow the blood vessels and meridians, and invade the internal organs. Its effect on cells should not be underestimated. Or disturb the metabolism of cells and disrupt the order of their biochemistry.
    After various experiments, observe its effects on animals. Observe its behavior and physiological changes, and analyze the data in detail. However, the study of toxicity is not achieved overnight. When repeated verification, it is clear that the dose is related to the effect. Only in this way can we know the depth of its toxicity, provide evidence for protection and application, and protect everyone from its harm, so that this product can be used properly and avoid harm.
    Future Prospects
    The future prospect concerns 2 - Fluoro - 4 - (Hydroxymethyl) Benzenecarbonitrile. I look at its quality, unique, and has infinite potential in the process of scientific research.
    Or it can be used for the research of new drugs, with its molecular structure, to attack difficult diseases. It is also expected to emerge in the field of materials, giving materials new energy, increasing their toughness and corrosion resistance.
    Furthermore, in chemical synthesis, it can be used as a key agent to expand the synthesis method and create new ways. With time and careful study, we will be able to shine brightly, contribute to the advancement of science and technology, and the benefit of people's livelihood, and become an extraordinary cause. This is the future situation that our generation looks forward to.
    Where to Buy 2-Fluoro-4-(Hydroxymethyl)Benzenecarbonitrile in China?
    As a trusted 2-Fluoro-4-(Hydroxymethyl)Benzenecarbonitrile manufacturer, we deliver: Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements. Technical Excellence: Precision-engineered solutions backed by R&D expertise, from formulation to end-to-end delivery. Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.
    Frequently Asked Questions

    As a leading 2-Fluoro-4-(Hydroxymethyl)Benzenecarbonitrile supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

    What is the main use of 2-Fluoro-4- (Hydroxymethyl) Benzenecarbonitrile?
    2-Fluoro-4- (hydroxymethyl) benzonitrile is one of the organic compounds. It has a wide range of uses and plays an important role in many fields.
    In the field of pharmaceutical chemistry, this compound is often a key intermediate. The way of pharmaceutical synthesis, with its special structure, can introduce specific functional groups to help build complex drug molecular structures. On this basis, drugs with unique biological activities can be synthesized for use against various diseases, such as antibacterial, anti-tumor drugs, or therapeutic drugs for neurological diseases.
    In the field of materials science, 2-fluoro-4- (hydroxymethyl) benzonitrile also has extraordinary performance. It can participate in the synthesis of polymer materials and improve the properties of materials by virtue of its chemical activity. For example, it can make materials have better stability, mechanical properties or optical properties, and then be applied to photoelectric materials, polymer films and other fields, contributing to the development of modern technology.
    Furthermore, in the fine chemical industry, it can be used as a raw material for the preparation of special chemicals. With its structural characteristics, through a series of chemical reactions, a variety of fine chemicals with special functions are generated, such as special dyes, fragrance additives, etc., to meet the market demand for diverse fine chemicals.
    In summary, 2-fluoro-4- (hydroxymethyl) benzonitrile, with its unique chemical structure, plays an indispensable role in many fields such as medicine, materials, and fine chemicals, and promotes the progress and development of related industries.
    What are the physical properties of 2-Fluoro-4- (Hydroxymethyl) Benzenecarbonitrile?
    2-Fluoro-4- (hydroxymethyl) benzonitrile, this property is also quite important. From the appearance point of view, it is mostly white to off-white solid at room temperature, and its texture is fine and slightly shiny in sunlight.
    In terms of its melting point, it is about a specific range, and this value is extremely critical for the identification and purification of this substance. The determination of the melting point can help to distinguish its purity. The melting point of the pure product is relatively fixed. If it contains impurities, the melting point may be offset.
    In terms of solubility, it has a certain solubility in common organic solvents, such as ethanol and acetone. Ethanol can form hydrogen bonds and other interactions with 2-fluoro-4- (hydroxymethyl) benzonitrile molecules, so it can dissolve a certain amount. In water, its solubility is poor, because although there are hydroxymethyl groups in the molecule that can form hydrogen bonds with water, the hydrophobic part of fluorine atoms and benzene rings has a greater influence, resulting in the whole being insoluble in water.
    Its density is also an important physical property. This value reflects the mass of its unit volume, which is of great significance in chemical production, material measurement, mixing and other operations.
    In addition, the stability of this substance is acceptable, and it can maintain its own structure and properties under normal temperature and pressure without the influence of special chemical reagents and light. However, when encountering strong acids and bases, their molecular structures may be affected and chemical reactions occur. For example, under the action of strong bases, cyano groups or hydrolysis are converted into carboxyl groups and other groups.
    From this perspective, the physical properties of 2-fluoro-4- (hydroxymethyl) benzonitrile lay the foundation for its application in chemical, pharmaceutical and other fields, and its physical properties can be used better.
    What are the synthesis methods of 2-Fluoro-4- (Hydroxymethyl) Benzenecarbonitrile?
    The synthesis of 2-fluoro-4- (hydroxymethyl) benzonitrile is an important topic in the field of organic synthesis. There are several common methods for the synthesis of this compound.
    First, fluorobenzene-containing derivatives are used as starting materials. First, fluorobenzene is introduced into the cyanyl group through a specific substitution reaction to construct the structural framework of benzonitrile. Later, hydroxymethyl is introduced into the specific position of the benzene ring with suitable reagents and conditions. This process requires precise control of reaction conditions, such as temperature, reaction time and reagent dosage, to achieve high selectivity and yield.
    Second, it can be started from benzonitrile derivatives. The fluorine atom is introduced at a specific position on the benzonitrile benzene ring first. This step may require the help of metal-catalyzed halogenation reaction and other means. Then a suitable reaction is used to introduce hydroxymethyl at the ortho-site of the fluorine atom. During this period, it is crucial to control the reactivity and selectivity. Due to different reaction conditions or side reactions, the purity and yield of the product are affected.
    Third, a multi-step tandem reaction strategy may be considered. By designing an ingenious reaction path, the starting material can construct the structure of each part of the target molecule in a series of successive reactions. This strategy can simplify the operation steps, reduce the cumbersome process of intermediate separation and purification, and improve the overall synthesis efficiency. However, a deeper understanding of the reaction conditions and mechanisms is required to achieve success.
    When synthesizing 2-fluoro-4- (hydroxymethyl) benzonitrile, attention should also be paid to the post-reaction treatment process. Appropriate separation and purification methods, such as column chromatography, recrystallization, etc., can effectively improve the purity of the product and meet the needs of subsequent experiments or applications. And different synthesis methods have their own advantages and disadvantages, and the optimal synthesis path should be carefully selected according to the actual situation, such as raw material availability, cost, target product purity requirements, etc.
    What are the precautions for 2-Fluoro-4- (Hydroxymethyl) Benzenecarbonitrile in storage and transportation?
    2-Fluoro-4- (hydroxymethyl) benzonitrile, an important organic compound, requires careful attention during storage and transportation.
    When storing, the drying environment is the first priority. Because of its hydroxyl and cyanyl groups, it is easily affected by water vapor and causes reactions such as hydrolysis, so the warehouse must be dry, and the humidity should be controlled at a low level to prevent moisture decomposition and deterioration. In addition, the temperature must also be reasonably regulated. This compound may be sensitive to temperature. Excessive temperature may cause it to decompose, polymerize, etc. Too low temperature may cause it to crystallize and solidify, which affects the use. Therefore, it should be stored in a cool place, and the temperature should be maintained in a specific range, generally 5 ° C - 25 ° C. At the same time, it is necessary to avoid light. Light may stimulate photochemical reactions and damage its structure. It should be stored in a light-shielding container or placed in a place without direct light.
    During transportation, packaging is essential. Suitable packaging materials need to be selected to ensure its sealing and stability. Because cyanide is toxic to a certain extent, the packaging must be able to effectively prevent leakage and be marked with clear warning labels to make the transporter aware of its danger. The means of transportation should also be clean, dry and free of fire. Avoid violent vibration and collisions during transportation to prevent package damage. If it is long-distance transportation, temperature, humidity and other conditions should also be checked regularly to ensure the stability of compound properties. If it is transported in high temperature in summer, cooling measures should be taken; when it is low temperature in winter, it is necessary to keep warm to prevent it from being damaged due to sudden temperature changes. In short, every step of storing and transporting 2-fluoro-4- (hydroxymethyl) benzonitrile must be treated carefully to ensure its quality and safety.
    What is the market outlook for 2-Fluoro-4- (Hydroxymethyl) Benzenecarbonitrile?
    There are currently 2-fluoro-4- (hydroxymethyl) benzonitrile, and we would like to know its market prospects. This substance may have unique uses in the field of chemical synthesis.
    Looking at the pharmaceutical chemistry, because it contains fluorine atoms, or gives drugs special biological activity and metabolic stability. In recent years, the research and development of medicine has increased the demand for compounds with such properties. Many new drugs are created, often relying on fluoroaromatic hydrocarbon derivatives. This 2-fluoro-4- (hydroxymethyl) benzonitrile may be a key intermediate, which is expected to become the cornerstone of new specific drug synthesis, so there may be potential business opportunities in the pharmaceutical market.
    In the field of material chemistry, the structure containing nitrile groups and hydroxymethyl groups can be chemically modified and polymerized to prepare special functional materials. If it is used in the synthesis of high-performance polymers, it provides materials with good mechanical properties, thermal stability or optical properties, and may have applications in the electronics, optical materials and other industries.
    However, its market prospects are also constrained by many factors. The complexity of the synthesis process is one of them. If the process is cumbersome and costly, it may limit its large-scale production and marketing activities. And the market competition situation should not be underestimated. If the same or alternative compounds have already prevailed, they need to have unique advantages in order to compete for a place.
    Although 2-fluoro-4- (hydroxymethyl) benzonitrile has potential opportunities in the field of medicine and materials, it is necessary to overcome synthesis problems and cope with competition in order to emerge in the market and gain a good prospect.