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2-Fluoro-4-Bromoiodobenzene

2-Fluoro-4-Bromoiodobenzene

Hongda Chemical

Specifications

HS Code

556531

Chemical Formula C6H3BrFI
Molecular Weight 300.89
Appearance Typically a liquid or solid, appearance may vary
Physical State At Room Temperature Likely liquid (dependent on purity and specific conditions)
Solubility Soluble in common organic solvents like dichloromethane, likely insoluble in water

As an accredited 2-Fluoro-4-Bromoiodobenzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

Packing & Storage
Packing 100g of 2 - fluoro - 4 - bromoiodobenzene packaged in a sealed glass bottle.
Storage 2 - fluoro - 4 - bromoiodobenzene should be stored in a cool, dry, well - ventilated area. Keep it away from heat sources, open flames, and oxidizing agents. Store in a tightly sealed container, preferably made of glass or a suitable chemical - resistant material, to prevent leakage and exposure to air or moisture, which could potentially lead to degradation or reaction.
Shipping 2 - fluoro - 4 - bromoiodobenzene is shipped in sealed, corrosion - resistant containers. It's carefully packed to prevent leakage during transit, following strict hazardous chemical shipping regulations to ensure safety.
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2-Fluoro-4-Bromoiodobenzene 2-Fluoro-4-Bromoiodobenzene
General Information
Historical Development
2-Fluoro-4-bromoiodobenzene is also a chemical substance. Its historical evolution can be described. In the past, chemists worked tirelessly in the field of organic synthesis to explore the properties and production methods of various compounds. When 2-fluoro-4-bromoiodobenzene first appeared, the synthesis method was still simple and the yield was not high. However, the public continued to work hard, and with the passage of time, the technology gradually refined. With the advancement of analytical methods, the deeper the understanding of its structure and characteristics. The preparation process has also been improved, and new reagents and new catalysis methods have emerged, resulting in improved yield and better purity. Therefore, 2-fluoro-4-bromoiodobenzene has been widely used in various fields such as medicine and materials, adding luster to the development of chemistry and laying the foundation for many scientific and technological breakthroughs. Its process is a microcosm of chemical progress.
Product Overview
Today, there is a substance called 2-Fluoro-4-Bromoiodobenzene. It is an organic compound and is of great value in the field of chemical research.
Looking at its structure, fluorine (Fluoro), bromine (Bromo) and iodo atoms are connected to the benzene ring. This unique structure gives this substance unique properties. The stability of the benzene ring, combined with the activity of the halogen atom, allows 2-Fluoro-4-Bromoiodobenzene to exhibit special behavior in many chemical reactions.
Because of the presence of halogen atoms, it can participate in nucleophilic substitution and other reactions, and is a key intermediate for the synthesis of complex organic molecules. Scientists often use it as a starting material, and through ingenious design and operation, they can build novel organic structures, which may open up new paths and bring different possibilities in drug development, materials science, and other aspects.
Physical & Chemical Properties
2 - Fluoro - 4 - Bromoiodobenzene is an organic compound. Its physical and chemical properties are very important. From the perspective of physical properties, at room temperature, this substance may be in a solid state, with a specific melting point and boiling point. The melting point is determined by the intermolecular force. The molecular structure is tight and the force is strong, and the melting point tends to be higher. The boiling point is also related to the attractive force between molecules. If the attractive force is large, higher energy is required to vaporize it, and the boiling point is also high.
Regarding the chemical properties, the activities of bromine, iodine and fluorine atoms in this compound are different. Halogen atoms have uneven electron cloud density distribution due to electronegativity differences. The iodine atom has a large radius, and the C-I bond energy is relatively small, so it is easy to replace, and can interact with nucleophiles, and the iodine atom is replaced. The fluorine atom has a large electronegativity, which reduces the electron cloud density of the benzene ring and decreases the activity of the electrophilic substitution of the benzene ring. These physicochemical properties are of great significance in the field of organic synthesis and provide the basis for related reactions and applications.
Technical Specifications & Labeling
2-Fluoro-4-bromoiodobenzene is also an organic compound. Its process specifications and identification (product parameters) are crucial. In terms of process specifications, the synthesis method needs to precisely control the temperature, duration and proportion of each reactant of the reaction. If a suitable halogenation reaction is used to make the fluorine, bromine and iodine atoms properly attached to the benzene ring, the reaction conditions are slightly poor, and the product is easy to be impure.
In terms of identification, it should have a clear name, that is, "2-Fluoro-4-Bromoiodobenzene", and its molecular formula, molecular weight and other parameters should be clearly stated. It should also be accompanied by accurate physical and chemical properties, such as melting point, boiling point, solubility, etc., so that users can properly apply it according to its characteristics and accurately grasp its performance in various chemical reactions.
Preparation Method
To prepare 2 - Fluoro - 4 - Bromoiodobenzene, the method is as follows:
In terms of raw materials, pure fluoride, bromide and iodine-containing raw materials are selected to ensure excellent texture. The preparation process involves mixing fluoride with a specific organic substrate in a certain ratio, and catalyzing with a specific catalyst at a suitable temperature and pressure to initiate the initial reaction to generate a fluorine-containing intermediate product.
Then, this intermediate product is fused with bromide in another reaction environment, the reaction conditions are controlled, the pH and reaction time are adjusted, and the bromine atom is precisely integrated to obtain a secondary intermediate product.
Finally, the iodine-containing raw materials are introduced, and the iodine atoms are connected in the optimized reaction system through clever reaction steps to complete the preparation of 2-Fluoro-4-Bromoiodobenzene. The whole process requires strict control of each reaction step and fine-tuning the conditions according to real-time monitoring data to ensure the purity and yield of the product, which is the key to preparing this product.
Chemical Reactions & Modifications
Today there is a substance called 2-Fluoro-4-Bromoiodobenzene. In the field of chemistry, its reaction and modification are extremely important.
To explore the reaction of this substance, it is necessary to observe its structure and properties. In its molecular structure, fluorine, bromine and iodine atoms are located in their respective positions and interact with each other. This structure makes it unique in many reactions.
When it comes to modification, different methods can be used. Or introduce new groups to change its chemical activity; or change the reaction conditions to adjust its reaction direction and rate.
In the process of organic synthesis, this substance can be used as a key intermediate. Many valuable products can be obtained by suitable reaction. In order to achieve the ideal modification effect, the reaction mechanism must be studied in detail and the reaction parameters must be carefully adjusted. In this way, 2-Fluoro-4-Bromoiodobenzene can be used well and fruitful results can be obtained in chemical research and production.
Synonyms & Product Names
2 - Fluoro - 4 - Bromoiodobenzene, this substance has various names in the field of my chemical research. Its scientific name is established, and common name aliases also exist. In the industry, or because of its structural characteristics, it has a similar name.
The name of a chemical substance is often based on its composition and structure, but the habits of all parties are different, resulting in synonyms. 2 - Fluoro - 4 - Bromoiodobenzene is named for its fluorine (fluoro), bromo (bromo), iodine (iodo) elements and the order is determined. However, between actual research and use, many researchers either because of convenience or follow the old practice, also have different names.
Although the names are different, they all refer to this thing. The subtlety of chemistry can also be seen in the name. The same thing has different names, which are all for the convenience of research and communication. It really refers to the unity. This is the interest of naming chemical substances.
Safety & Operational Standards
Safety and operation of 2-fluoro-4-bromoiodobenzene
2-fluoro-4-bromoiodobenzene is also an important substance in chemical research. To use it properly, it is essential to understand its safety and operation standards.
In terms of safety, this substance has certain potential hazards. It may have irritating effects on the skin, eyes and respiratory tract. Therefore, when operating, be fully armed, wear protective clothing, protective gloves and goggles to prevent skin and eyes from touching it. Work in a well-ventilated place, or use a fume hood, so as to avoid inhaling its volatile gas and keep the respiratory tract safe.
Discuss the operating specifications. When taking it, the action should be slow and careful, and clean and precise utensils should be used to prevent leakage. When weighing, follow the precise process to ensure that the dosage is correct. When storing, it should be placed in a cool, dry and ventilated place, away from fire and heat sources, and stored separately from oxidants and acids. Do not mix storage to avoid chemical reactions and cause danger.
If it is unfortunate to touch the skin, rinse with plenty of water as soon as possible, and then seek medical treatment. If it enters the eye, also rinse with plenty of water, and seek medical assistance if necessary. If you inhale accidentally, leave the scene to a fresh air place as soon as possible. If you feel unwell, seek medical attention urgently.
In short, the operation of 2-fluoro-4-bromoiodobenzene must always keep in mind safety first and strictly follow the operating specifications, so as to ensure the safety of the experiment and personnel.
Application Area
Today there is a product called 2 - Fluoro - 4 - Bromoiodobenzene. The application field of this product is quite wide. In the field of medicinal chemistry, it can be used as a key intermediate to help create new drugs to cure various diseases. In the field of materials science, it can participate in the preparation of special materials, so that the material has unique properties, such as excellent photoelectric properties. In the field of organic synthesis, with its special chemical structure, it can open up novel synthesis paths and provide the possibility for the synthesis of complex organic compounds. From this perspective, 2-Fluoro-4-Bromoiodobenzene is of great value in many fields and is an indispensable substance. Its application prospects are also very broad, and it will surely contribute to the development of various fields.
Research & Development
In recent years, I have been involved in chemical substances, especially 2 - Fluoro - 4 - Bromoiodobenzene. This material is very different and has great potential for organic synthesis.
I began to study this substance, studying its structure in detail and exploring the root of its nature. After repeated trials, I knew the rules of its reaction. Combine it with various reagents, observe its changes, record its numbers, and analyze its results.
At the beginning, the method of synthesis was not good, and the yield was quite low. However, I was not discouraged, so I studied the classics, consulted the experience of others, and changed the method. In the end, I obtained a good method, the yield gradually increased, and the quality was also excellent.
Now looking at this thing, the application is becoming more and more widespread. In the manufacture of medicine, it can become a special agent; in the manufacture of materials, it can innovate strange qualities. I hope that in the future, its development will be more prosperous, contributing to the progress of chemistry and benefiting the world.
Toxicity Research
Study on the toxicity of 2-fluoro-4-bromoiodobenzene
Fu 2-fluoro-4-bromoiodobenzene is a chemical substance. In today's chemical industry, its use is becoming more and more extensive. However, the study of its toxicity should not be ignored.
Looking at past studies, the toxicity of 2-fluoro-4-bromoiodobenzene is related to contact, inhalation, or percutaneous, or accidental ingestion. Inhalation can damage the respiratory system, cause inflammation of the airway, and even lung diseases. Touch it through the skin, or cause skin allergies, redness, swelling, itching, and pain. If eaten by mistake, it will hurt the stomach and intestines, causing vomiting and diarrhea.
And the test of its toxicity also involves the biological body. In animal tests, it can affect the function of organs, damage liver and kidney functions, disturb the nervous system, and cause behavioral differences. Although this is the case, it is still necessary to study its toxicology in depth, to understand its exact harm to the human body, in order to establish a complete prevention, protect the well-being of the public, and avoid the injury of poisons.
Future Prospects
Husband 2 - Fluoro - 4 - Bromoiodobenzene, it is also a matter of transformation. Today, it is unique, and it has the power to create. In the future, I expect it will be extraordinary.
Or it can be used in the field of refinement and synthesis to synthesize delicate molecular pathways. Its special atomic arrangement can lead to novel reactions and create unprecedented compounds.
It is also expected to show its skills in research and development. Or it can be used in the middle of the process, to help new manufacturing, and to cure the dawn of the disease.
And in the field of materials, it may be able to give materials special properties, such as the transformation of optical properties, to make materials new appearance.
In the future, 2 - Fluoro - 4 - Bromoiodobenzene is full of hope and will surely be able to expand new worlds and achieve extraordinary achievements in many fields.
Where to Buy 2-Fluoro-4-Bromoiodobenzene in China?
As a trusted 2-Fluoro-4-Bromoiodobenzene manufacturer, we deliver: Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements. Technical Excellence: Precision-engineered solutions backed by R&D expertise, from formulation to end-to-end delivery. Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.
Frequently Asked Questions

As a leading 2-Fluoro-4-Bromoiodobenzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

What are the main uses of 2-Fluoro-4-Bromoiodobenzene?
2-Fluoro-4-bromoiodobenzene, an important compound in organic chemistry, has key uses in many fields.
First, in the field of drug synthesis, this compound is often used as a key intermediate. In the process of drug development, the structure of organic molecules needs to be precisely designed and constructed to achieve the expected pharmacological activity. The halogen atom of 2-fluoro-4-bromoiodobenzene can be connected with other organic fragments through various chemical reactions, such as nucleophilic substitution reactions, metal-catalyzed cross-coupling reactions, etc., to construct drug molecules with complex structures and specific activities. For example, in the development of anti-tumor drugs, scientists can modify their structures and introduce specific pharmacoactive groups to develop new anti-cancer drugs with high efficiency and low toxicity.
Second, in the field of materials science, 2-fluoro-4-bromoiodobenzene also plays an important role. In the synthesis of organic optoelectronic materials, the compound can be chemically modified to prepare materials with unique optoelectronic properties. Due to its halogen atom properties, the electron cloud distribution and energy level structure of the material can be adjusted, thereby improving the conductivity and fluorescence emission of the material. Such materials may be applied in the fields of Light Organic Emitting Diode (OLED), solar cells, etc., to improve the performance and efficiency of related devices.
Furthermore, in the study of organic synthetic chemistry, 2-fluoro-4-bromoiodobenzene is a commonly used synthetic block, providing a convenient way to construct complex organic molecular structures. Chemists can use ingenious design of reaction routes to take advantage of the reactivity differences of halogen atoms to carry out various reactions in an orderly manner and achieve precise synthesis of complex molecules. This not only helps to explore and develop new organic synthesis methods, but also lays a solid foundation for the development of new functional materials and drugs.
What are the physical properties of 2-Fluoro-4-Bromoiodobenzene?
2-Fluoro-4-bromoiodobenzene is also an organic compound. It has unique physical properties and can be described in detail.
First of all, under normal temperature and pressure, 2-fluoro-4-bromoiodobenzene is often in a liquid state, and it can be seen that the clear and transparent state, such as crystal clear liquid, flows and shines. This state is convenient for participating in reactions in many chemical reaction systems. Because of its liquid shape, intermolecular contact is more convenient, and the reaction is easy to carry out.
Second, its melting point and boiling point. The melting point is also the critical temperature for the substance to change from solid to liquid. The melting point of 2-fluoro-4-bromoiodobenzene is very low, causing it to be liquid at room temperature. With this characteristic, in practical applications, it can be in a liquid state without excessive temperature, participating in various liquid-phase reactions, saving energy and increasing efficiency. As for the boiling point, it is the temperature at which the substance changes from the liquid state to the gaseous state under a specific pressure. Its boiling point is relatively moderate. This characteristic makes it possible to separate and purify this compound by distillation in a suitable temperature range to achieve the purpose of separation and ensure its purity.
Furthermore, when it comes to density. The density of 2-fluoro-4-bromoiodobenzene is greater than that of water. When it is co-placed with water, it can be seen that it sinks underwater and the stratification is clear. This density characteristic is very important in separation operations such as extraction. According to its density difference with water, a suitable organic solvent can be selected for effective separation.
Solubility is also an important property. 2-Fluoro-4-bromoiodobenzene has good solubility in organic solvents such as ethanol, ether, and dichloromethane, and can be miscible with various organic solvents. This property facilitates organic synthesis because it often needs to be reacted in a specific organic solvent system. Good solubility ensures that it is uniformly dispersed in the reaction system, fully participates in the reaction, and improves the yield and efficiency of the reaction. However, its solubility in water is extremely poor and almost insoluble, and this property also helps to purify it by aqueous-organic phase separation means.
In addition, 2-fluoro-4-bromoiodobenzene is volatile to a certain extent and will evaporate slowly in the air. Although the volatility is not strong, it is still necessary to pay attention during operation. It is advisable to operate in a well-ventilated place to prevent its vapor accumulation and affect the experimental environment and the health of the experimenter.
In summary, the physical properties of 2-fluoro-4-bromoiodobenzene, such as liquid properties, specific melting and boiling points, density, solubility and volatility, are of great significance in many fields such as organic synthesis, separation and purification, laying the foundation for its wide application.
What are 2-Fluoro-4-Bromoiodobenzene synthesis methods?
The synthesis method of 2-fluoro-4-bromoiodobenzene has always been ancient. To make this substance, you can start from several ways.
First, the benzene derivative containing fluorine and bromine is used as the starting material. First, bromine atoms are introduced at specific positions on the benzene ring. Commonly used brominating reagents, such as liquid bromine, can undergo electrophilic substitution reactions at specific check points of the benzene ring under the action of appropriate catalysts, such as iron or iron tribromide, and bromine atoms are precisely introduced. When the bromine atoms are in place, iodine atoms are introduced. The method of introducing iodine atoms can be used to react with iodide and benzene ring derivatives. For example, under the catalysis of copper salts, iodine ions undergo nucleophilic substitution reaction with appropriate leaving groups on the benzene ring, thereby introducing iodine atoms. In this process, the reaction conditions need to be carefully regulated, such as temperature, reaction time, and reagent dosage, etc., to ensure that the reaction proceeds in the desired direction and a higher yield product is obtained.
Second, benzene derivatives containing iodine and fluorine can also be started. First, fluorine atoms are introduced into the benzene ring, and special reagents and conditions are usually required for fluorination reactions. Suitable fluorinated reagents, such as Selectfluor, can be selected. In the presence of appropriate solvents and catalysts, fluoride reactions occur at specific positions in the benzene ring. Then The introduction of bromine atoms also relies on the electrophilic substitution reaction to control the reaction conditions, so that the bromine atoms fall exactly at the desired position, and finally obtain 2-fluoro-4-bromoiodobenzene.
Furthermore, based on halobenzene, fluorine, bromine and iodine atoms are gradually introduced. First select the appropriate halobenzene, and plan the introduction sequence reasonably according to the difference in reactivity. Generally speaking, the more reactive groups are introduced first, and then other groups are introduced in sequence. During the reaction process, attention should be paid to the selectivity and yield of each step. By optimizing the reaction conditions, such as selecting suitable solvents, temperature regulation, catalyst screening, etc., the purity and yield of the product can be improved to achieve the synthesis of 2-fluoro-4-bromoiodobenzene.
What is the market price of 2-Fluoro-4-Bromoiodobenzene?
Today, I have a question about the market price of 2-fluoro-4-bromoiodobenzene. This is a fine chemical, and its price changes frequently and is influenced by many factors.
The first to bear the brunt is the difficulty of preparation. Synthesis of 2-fluoro-4-bromoiodobenzene requires a fine organic synthesis method, and the raw materials and steps used are quite complicated. If the raw materials are rare and difficult to find, or the synthesis process conditions are harsh, if precise temperature and pressure control are required, and the help of special catalysts is required, the cost will rise, resulting in a high market price.
Furthermore, the market supply and demand situation is also critical. If many industries, such as pharmaceutical research and development, materials science, etc., have strong demand for 2-fluoro-4-bromoiodobenzene, but limited supply, if there are few production enterprises and insufficient production capacity, according to the reason of supply and demand, the price will rise. On the contrary, if the demand is low and the supply exceeds the demand, the price will drop.
Product purity also affects the price. High-purity 2-fluoro-4-bromoiodobenzene, due to the need for finer purification processes, consumes more resources and energy, and the price is often higher than that of low-purity products. In the fields of medicine, electronics, etc., the purity requirements are extremely high, and high-purity products have a market even if they are expensive.
In addition, market competition, international situation, and fluctuations in raw material prices will all affect its prices. Therefore, to know the exact market price of 2-fluoro-4-bromoiodobenzene, it is necessary to carefully check the real-time quotation of the chemical product trading platform, or consult the relevant manufacturers and distributors to obtain a more accurate figure.
What are the precautions in storage and transportation of 2-Fluoro-4-Bromoiodobenzene?
2-Fluoro-4-bromoiodobenzene is an organic compound. When storing and transporting, many matters need to be paid careful attention.
Its chemical properties are the first. This compound contains fluorine, bromine, iodine and other halogen atoms, which are highly chemically active and prone to chemical reactions when encountering specific reagents. Therefore, when storing, be sure to keep it away from active substances such as strong oxidants, strong bases, and strong acids. If it comes into contact with it, it may cause violent reactions and even the risk of explosion.
Secondary and stability and environmental factors. 2-Fluoro-4-bromoiodobenzene is sensitive to light and heat. Light or high temperature can easily cause it to decompose, thus affecting the quality and purity. Therefore, it should be stored in a cool, dry and dark place. The best storage temperature should be maintained in the low temperature range, usually 2-8 ° C. And it is necessary to ensure that the storage environment is well ventilated to prevent danger due to volatile accumulation.
The other is packaging. When storing and transporting, the packaging must be tight. Appropriate packaging materials should be used, such as glass bottles or plastic containers with good chemical resistance. Glass bottles should be guaranteed to be free of cracks, and plastic containers should also be able to resist corrosion of this compound. Key information such as their name, nature, and hazard warnings should also be clearly marked on the outside of the package for identification and prevention.
Transportation should not be ignored. Vibration, collision and friction should be avoided during transportation to prevent package damage. If it is transported by road, it is necessary to choose vehicles that meet the transportation standards of hazardous chemicals, and to be equipped with necessary emergency treatment equipment and protective equipment. When transporting by rail or air, it is even more necessary to strictly follow relevant regulations and procedures and go through complete transportation procedures.
In short, the storage and transportation of 2-fluoro-4-bromoiodobenzene requires careful operation, and the chemical properties, environmental factors, packaging and transportation process should be carefully considered, so as to ensure its safety and stability and avoid accidents.