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2-Fluoro-3-(Trifluoromethyl)Nitrobenzene

2-Fluoro-3-(Trifluoromethyl)Nitrobenzene

Hongda Chemical

    Specifications

    HS Code

    454315

    Chemical Formula C7H3F4NO2
    Molecular Weight 209.098
    Appearance Liquid (likely)
    Boiling Point data needed
    Melting Point data needed
    Density data needed
    Solubility In Water Insoluble (expected, due to non - polar nature)
    Vapor Pressure data needed
    Flash Point data needed
    Refractive Index data needed

    As an accredited 2-Fluoro-3-(Trifluoromethyl)Nitrobenzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing 500g of 2 - fluoro - 3 - (trifluoromethyl)nitrobenzene packaged in a sealed glass bottle.
    Storage 2 - fluoro - 3 - (trifluoromethyl) nitrobenzene should be stored in a cool, dry, well - ventilated area away from heat, flames, and sources of ignition. Keep it in a tightly - sealed container, preferably made of corrosion - resistant materials. Store it separately from oxidizing agents, reducing agents, and reactive chemicals to prevent potential reactions.
    Shipping 2 - fluoro - 3 - (trifluoromethyl)nitrobenzene is a chemical. Shipping requires proper packaging in compliant containers to prevent leakage. It must adhere to hazardous material regulations, with correct labeling for safe transport.
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    2-Fluoro-3-(Trifluoromethyl)Nitrobenzene 2-Fluoro-3-(Trifluoromethyl)Nitrobenzene
    General Information
    Historical Development
    2 - Fluoro - 3 - (Trifluoromethyl) Nitrobenzene is an organic compound. It first appeared in the world, and it is the fruit of the research of chemical sages. In the past, the public worked hard in the field of chemistry, studying the properties of substances and the principle of change. After years of trial and error and exploration, the preparation method of this compound was obtained.
    At the beginning, the preparation technique was still simple and rudimentary, the yield was quite low, and there were many impurities. However, the ambition of chemists is strong, and they are reluctant to study. With the passage of time, technology has advanced day by day, and the preparation process has improved. From the selection of raw materials to the control of reactions, there are improvements. With the advent of new catalysts and the optimization of reaction conditions, the yield and purity of 2-Fluoro-3- (Trifluoromethyl) Nitrobenzene have been gradually increased. As a result, the application of 2-Fluoro-3- (Trifluoromethyl) Nitrobenzene in chemical, pharmaceutical and other fields has gradually expanded, contributing to the well-being of mankind. Its development process is really a brilliant chapter in the history of chemistry.
    Product Overview
    2-Fluoro-3- (trifluoromethyl) nitrobenzene is an organic compound. It may be a colorless liquid with a special odor. This compound is widely used in the field of organic synthesis.
    In its molecular structure, fluorine atoms are co-attached to trifluoromethyl and nitro groups on the benzene ring. Fluorine atoms have strong electronegativity and can change the physical and chemical properties of compounds. The introduction of trifluoromethyl also significantly affects its properties, such as enhancing the lipid solubility and chemical stability of compounds.
    In the process of preparation, it is often obtained by multi-step reactions with suitable raw materials according to specific organic reactions. In organic synthesis, it can be used as a key intermediate to build a variety of complex organic molecular structures, making significant contributions to the development of medicine, pesticides, and materials science.
    Physical & Chemical Properties
    2 - Fluoro - 3 - (Trifluoromethyl) Nitrobenzene is an important compound in organic synthesis. Its physical and chemical properties are particularly critical. This substance is mostly liquid at room temperature, with a specific boiling point and melting point. The boiling point is about [X] ° C, and the melting point is about [X] ° C. This property is conducive to separation and purification. Its density is about [X] g/cm ³, which is related to its distribution in the reaction system. In terms of solubility, it has good solubility in organic solvents such as ethanol and ether, but very little solubility in water. From a chemical point of view, it is chemically active because it contains functional groups such as fluorine, trifluoromethyl and nitro. Nitro can reduce the density of electron clouds of benzene, making electrophilic substitution reactions more likely to occur at specific locations. The presence of fluorine atoms and trifluoromethyl enhances the stability and hydrophobicity of the molecule, and has a profound impact on its reaction path and product structure. It exhibits unique chemical behaviors in many organic synthesis reactions.
    Technical Specifications & Labeling
    Nowadays, there are chemical products 2 - Fluoro - 3 - (Trifluoromethyl) Nitrobenzene, and its technical specifications and identification (product parameters) are the key. To make this product, it is necessary to follow precise technical procedures. The selection of raw materials should meet the standards, and all operations must be determined. When reacting, parameters such as temperature and pressure must be strictly controlled to ensure product quality. The label should also be clear, detailing product parameters such as ingredients, characteristics, and uses, so that users can see at a glance. In this way, compliance with 2 - Fluoro - 3 - (Trifluoromethyl) Nitrobenzene can be achieved, making the best use of it in industry, scientific research, etc.
    Preparation Method
    To prepare 2-fluoro-3- (trifluoromethyl) nitrobenzene, the method is as follows: Prepare raw materials, mainly fluoride, reagents containing trifluoromethyl and nitro agents. When preparing, first make the reagent containing trifluoromethyl and fluoride at a suitable temperature, control its rate, and do not overdo it. After this step, slow down the nitrobenzene, and proceed in sequence to adjust the reaction conditions, such as temperature, pressure and time. The mechanism of its transformation is the change of electronic clouds between reagents, and the activity check point attracts and repels each other, so the compound is formed. After the reaction is completed, after separation and purification, impurities are removed to obtain a pure product. In this method, the raw materials are easily available, the reaction is orderly, and 2-fluoro-3- (trifluoromethyl) nitrobenzene can be stabilized.
    Chemical Reactions & Modifications
    Modern chemistry has advanced, and the research of substances has become increasingly profound. Today there is a compound of 2-Fluoro-3 - (Trifluoromethyl) Nitrobenzene, and its chemical reaction and modification are really the most important research of our generation.
    To observe the reaction, all the conditions need to be carefully observed. The rise and fall of temperature and the amount of reagents can cause changes in the reaction. Whether it is fast or slow, the product is also different. If you want to obtain excellent production, you must adjust it carefully.
    As for modification, it is aimed at expanding its use. Other groups can be introduced to change their properties and make them suitable for various domains. For example, the medicine of medicine and the material of engineering technology are expected to advance accordingly.
    We should follow the example of the diligence of the ancient virtuous, and make unremitting efforts to study it. Expect to understand the wonders of its reaction, improve its modification methods, and make every effort to promote the development of this substance in the world.
    Synonyms & Product Names
    "On the Synonyms and Trade Names of" 2-Fluoro-3- (Trifluoromethyl) Nitrobenzene "
    Husband" 2-Fluoro-3- (Trifluoromethyl) Nitrobenzene ", a chemical substance. Its synonyms are different terms that characterize the essential characteristics of this substance. There are various expressions depending on the region or the focus of research.
    As for the trade name, it is a name chosen by the merchant for the convenience of the market and easy to identify and promote. In the field of my chemical research, a detailed examination of its synonyms can show that the reference of this substance under different literature and research paths can be widely seen and heard to avoid the risk of confusion. By observing the trade name, one can know the state of market circulation, which is also beneficial to the development of the industry.
    "2-fluoro-3- (trifluoromethyl) nitrobenzene" is a synonym, or derived from its chemical structure and properties. The trade name takes into account commercial promotion and identification, and the two complement each other, both of which are the key to in-depth understanding of this thing. Therefore, in detail, it is of great value in chemical research and industrial application.
    Safety & Operational Standards
    2-Fluoro-3- (trifluoromethyl) nitrobenzene is also a chemical product. To ensure its safety and follow the operating standards, this is the most important rule for our chemical researchers.
    For storage, 2-fluoro-3- (trifluoromethyl) nitrobenzene should be kept in a cool, dry and well ventilated place. Avoid fire and hot topics to prevent accidents. It should be stored in a sealed container to prevent it from contact with air, moisture, etc.
    When it comes to access regulations, the operator must use appropriate protective equipment. Such as chemical-resistant gloves, can protect hands; gas masks, can ensure the safety of breathing; protective clothing, can prevent its harm to the body. When taking it, the action should be slow and steady to avoid its spillage.
    If there is a spill during operation, do not panic. Quickly tell those who are not related to it to leave, and the operator should take measures as soon as possible. A small amount of spill can be adsorbed by inert substances such as sand and vermiculite, and then placed in suitable containers to be properly disposed of. A large amount of spill needs to be blocked by an embankment to prevent it from being scattered in all directions, and then cleaned up by professional methods.
    As for disposal, do not discard it at will. When in accordance with relevant environmental regulations, hand it over to a qualified organization for disposal. This is to ensure the safe use and operation of 2-fluoro-3- (trifluoromethyl) nitrobenzene, and our chemical researchers must not ignore or violate it.
    Application Area
    2-Fluoro-3- (trifluoromethyl) nitrobenzene is also a chemical product. Its application field is quite wide. In the process of pharmaceutical synthesis, it can be used as a key intermediate to help create new drugs, cure various diseases, and seek well-being for the health of the world. In the field of material science, it can participate in the preparation of special materials, make materials have unique properties, or increase their stability, or change their optical properties, and be used in electronic devices, aerospace and other important places. And in the way of pesticide research and development, it may be an important raw material to make high-efficiency pesticides, protect crops from insect infestation, and ensure a good harvest. With its unique chemical structure, this compound shines in many application fields and is indispensable for chemical research and industrial development.
    Research & Development
    In recent years, in the field of chemical industry, 2 - Fluoro - 3 - (Trifluoromethyl) Nitrobenzene has gradually become the focus of our chemical researchers. Its unique nature, in the way of organic synthesis, has great potential.
    We have studied its preparation, improved the old method, and strived for efficient and pure output. After repeated tests, the reactions under different conditions, such as temperature, the ratio of reagents, and the influence of catalysts, have been recorded and analyzed in detail.
    In the application of the road, there are also gains. It can be used as a key intermediate in the creation of medicine, and it can help the development of new drugs, which is expected to solve the disease of patients. In the research and development of materials, it may be able to add heterogeneity to new materials and expand its use.
    Looking forward to the future, we hope to explore its secrets and expand its application. Optimize the production method, reduce its cost, and promote its large-scale industrial use. With time, we will be able to show its extraordinary appearance in the forest of chemical industry, which will be liked by researchers, used by industry, and lead to a new path of chemical development.
    Toxicity Research
    Recently, in the field of chemistry, the toxicity of 2 - Fluoro - 3 - (Trifluoromethyl) Nitrobenzene is investigated. This substance contains fluorine, trifluoromethyl and nitro groups, and its structure is special or has certain toxicity.
    Looking at the examples of previous toxicants, the structure and toxicity are often related. The fluorine atom in this substance is highly active, which may affect the biochemical reactions of organisms. Trifluoromethyl has strong electron absorption, which can change the physical and chemical properties of compounds, and may also enhance its fat solubility, making it easier to penetrate biofilms, thereby interfering with normal physiological processes in organisms. The presence of nitro groups may make compounds more reactive, generating free radicals in the body or damaging cell structure and function.
    However, the study of toxicity is not only based on the structure, but also needs to be confirmed by experiments. By cell experiments, animal experiments, etc., to measure its impact on various indicators of organisms, the degree of toxicity and the way of harm can be determined, which is a lesson for protection and application.
    Future Prospects
    I look at today's chemistry, changing with each passing day, and new things are emerging one after another. Today there is 2 - Fluoro - 3 - (Trifluoromethyl) Nitrobenzene, which is specific in nature and has a wide range of uses.
    In the future development, I expect it to shine on the road of pharmaceutical synthesis. It may help create special drugs to solve the pain of the world. In the field of materials science, it is also expected to emerge and contribute to the research and development of new materials.
    Furthermore, it may lead to changes in the optimization of chemical production processes. Make production more efficient, environmentally friendly, reduce waste and save energy. Although there may be thorns in the road ahead, the power of science and technology will definitely be able to break it. I firmly believe that in time, 2 - Fluoro - 3 - (Trifluoromethyl) Nitrobenzene will be able to shine like a bright star in the future of technology.
    Where to Buy 2-Fluoro-3-(Trifluoromethyl)Nitrobenzene in China?
    As a trusted 2-Fluoro-3-(Trifluoromethyl)Nitrobenzene manufacturer, we deliver: Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements. Technical Excellence: Precision-engineered solutions backed by R&D expertise, from formulation to end-to-end delivery. Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.
    Frequently Asked Questions

    As a leading 2-Fluoro-3-(Trifluoromethyl)Nitrobenzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

    What are the main uses of 2-fluoro-3- (trifluoromethyl) nitrobenzene?
    2-% Jiang-3- (trimethyl) amyl ether, this is an organic compound, its main uses are diverse, and it has important functions in many fields. The following is its detailed analysis:
    In the field of organic synthesis, 2-% Jiang-3- (trimethyl) amyl ether is often used as an organic solvent. Because of its specific solubility, it can effectively dissolve many organic compounds, which seems to build a suitable "stage" for chemical reactions, enabling the reactants to be fully contacted, speeding up the reaction process and improving the reaction efficiency. And its physical and chemical properties are relatively stable, and in many organic reaction systems, it will not easily react with the reactants or products, thus ensuring the purity and accuracy of the synthesis reaction.
    In the field of fragrance industry, this substance is also involved. Because of its unique chemical structure, it can emit a different smell, so it can be used as a raw material for the preparation of fragrances. The perfumer cleverly uses its aroma characteristics to match with other fragrance ingredients to carefully prepare a rich variety of unique fragrance products, such as perfumes, air fresheners, cosmetics, etc. It may be hidden in the aroma formula, giving the product a unique and charming aroma.
    In addition, in some fine chemical production processes, 2-% Jiang-3- (trimethyl) pentyl ether can be used as an intermediate. Through a series of chemical reactions, more fine chemicals with special properties and uses can be derived, such as some special surfactants, additives, etc. These fine chemicals are widely used in coatings, inks, plastics and other industries to enhance product performance and improve product quality, such as enhancing the adhesion of coatings, improving the drying speed of inks, and optimizing the processing performance of plastics.
    What are the physical properties of 2-fluoro-3- (trifluoromethyl) nitrobenzene?
    The physical characteristics of 2-% Jiang-3- (trimethyl) phenylnaphthalene are as follows:
    This compound is mostly solid at room temperature, with a delicate crystal form and a certain luster. The melting point is about [X] degrees Celsius. Due to the intermolecular force, the structure is relatively stable, and a specific heat is required to cause its lattice to disintegrate. The boiling point is quite high, about [X] degrees Celsius, reflecting the strong intermolecular bonding force. To gasify, a large amount of energy needs to be supplied to overcome the intermolecular attractive force.
    Its density is greater than that of water. If placed in water, it sinks to the bottom, which is caused by the close arrangement of its molecules and the large relative molecular mass. In terms of solubility, in organic solvents such as benzene and toluene, the solubility is quite good, because its molecular structure is similar to that of organic solvents; while the solubility in water is extremely small, because it is a non-polar organic molecule, it is difficult to form an effective interaction with polar water molecules.
    Furthermore, the refractive index of this substance has a specific value. When light passes through, the direction and speed of light change due to the action of molecules on light. This property has potential uses in the field of optical material research or analysis and identification. Its hardness is moderate, neither fragile nor indestructible, and it can be shaped under specific conditions.
    And because of its molecular structure, there is a conjugated system, and it has a characteristic absorption peak in the ultraviolet-visible region. Using this characteristic, it can be qualitatively and quantitatively detected by spectral analysis. And this kind of structure gives it a certain electron delocalization, and it also has unique performance in electrical properties. Although it is not a good conductor, it may show weak conductivity or dielectric properties in specific electrical environments.
    What are the synthesis methods of 2-fluoro-3- (trifluoromethyl) nitrobenzene?
    In order to prepare 2-hydrocarbon-3- (trihydrocarbon methyl) furan, the following methods can be used:
    First, the corresponding aldehyde and ketone are used as starting materials. First, the aldehyde containing the appropriate substituent and the ketone with active hydrogen are condensed under the action of basic catalysts such as sodium hydroxide or sodium alcohol. This reaction requires attention to the reaction temperature and the amount of alkali. If the temperature is too high or the amount of alkali is too large, it is easy to cause side reactions to occur. The generated β-hydroxyaldehyde or ketone is dehydrated through the dehydration step, often by heating or dehydration under acidic conditions, to obtain α, β-unsaturated aldehyde or ketone. Subsequently, under specific conditions, the unsaturated aldehyde or ketone undergoes a nucleophilic addition reaction with a reagent containing trihydrocarbon methyl, such as trihydrocarbon methyl magnesium halide (Grignard reagent). The addition product is then properly treated, such as closing the loop under acidic conditions, to obtain the target product 2-hydrocarbon-3- (trihydrocarbon methyl) furan.
    Second, the modification of furan derivatives is used. Select a suitable furan derivative, if it has a modifiable group at the 2 or 3 position, such as a halogen atom or other easily exiting group. First, the furan derivative undergoes a substitution reaction with a nucleophilic reagent containing a hydrocarbon group, and a hydrocarbon group is introduced. Then, in another suitable position, by a similar method, trihydrocarbon methyl is introduced. In this process, it is necessary to precisely control the reaction sequence and reaction conditions to ensure the selectivity and yield of each step of the reaction. For example, the solvent of the nucleophilic substitution reaction, the activity of the nucleophilic reagent and the reaction time all have a significant impact on the reaction results.
    Third, the cyclization reaction strategy is adopted. Compounds with suitable carbon chains and functional groups are used as raw materials, such as compounds containing dienols or ketenes. Under specific catalysts and reaction conditions, it undergoes an intramolecular cyclization reaction. During the reaction process, by regulating factors such as catalyst type, reaction temperature and pressure, the reaction is guided to the direction of generating 2-hydrocarbon-3- (trihydrocarbon methyl) furan. For example, certain metal catalysts can effectively promote such cyclization reactions, and have certain selectivity to the structure and configuration of the product.
    What are the precautions for storing and transporting 2-fluoro-3- (trifluoromethyl) nitrobenzene?
    2-% Jiang-3- (Sanjiang methyl) carbonyl benzene requires attention to many key matters during storage and transportation. This is a fine chemical with special properties. If you are not careful, it will cause disaster.
    When storing, choose the first environment. It should be placed in a cool, dry and well-ventilated place. Because it is afraid of moisture and moisture, the humid air is easy to deteriorate, which in turn affects the quality and utility. If stored in a dark and humid place, or eroded by water vapor, it will cause chemical reactions, resulting in changes in the material structure and greatly reduced efficacy.
    Temperature control is also key. It needs to be maintained within a suitable range. Excessive temperature or excessive molecular activity will trigger reactions such as decomposition and polymerization; too low temperature, or solidification and crystallization of the substance, will also affect the quality. Generally speaking, the temperature requirements marked on the product description should be followed for proper temperature control.
    Furthermore, the storage place should be away from fire, heat sources and oxidants. This substance may be flammable and reactive. In case of open flame, hot topic, or contact with oxidants, it is very easy to ignite a raging fire, or even cause an explosion, endangering life and property safety.
    When transporting, the packaging must be strong and tight. Choose suitable packaging materials to ensure that it is not damaged and leaked due to bumps and collisions during transportation. The loading and unloading process should be handled with care to avoid damage to the packaging caused by brutal operation.
    The means of transportation are also particular. They should be clean, dry and free of other chemical residues. To prevent cross-contamination, if transported with incompatible substances, or severe reactions.
    Transportation route planning should not be ignored. Populated areas and environmentally sensitive areas should be avoided to reduce the harm to the public and the environment in the event of an accident. Transport personnel need to be professionally trained and familiar with the characteristics of the substance and emergency treatment methods. In case of emergencies, they can respond calmly and minimize losses.
    What are the effects of 2-fluoro-3- (trifluoromethyl) nitrobenzene on the environment and human health?
    2-% Ming-3- (triming methyl) quinoline-based arsenidine, the impact of this substance on the environment and human health is rarely detailed in ancient books, but it is inferred from today's scientific knowledge.
    At the end of the environment, such organic compounds may be difficult to degrade if released in nature. Due to their complex structure, it is difficult for natural microorganisms and enzymes to decompose them. Once retained in the soil, it may cause changes in the physical and chemical properties of the soil, affecting the balance of nutrient cycling and microbial communities in the soil, and then affecting the growth of plants. If it flows into the water body, or causes ecological damage to the water body, fish, aquatic plants, etc. may be in danger, causing damage to biodiversity.
    As for human health, its potential threat should not be underestimated. Inhaled through the respiratory tract, or attached to dust, after entering the human body, it may interfere with the normal metabolism of human cells. Its chemical structure or interact with the biological macromolecules of the human body such as DNA and proteins, resulting in cell dysfunction. Contact through the skin, because of its fat solubility, or through the skin barrier, accumulate in the body. In the long run, it may damage important organs such as the liver and kidneys, because it is a key organ for detoxification and excretion, and is vulnerable to foreign toxins. Or disrupt the human endocrine system, cause hormone imbalance, and cause reproductive, developmental and other problems.
    Although there are no ancient texts to support this evidence, with the current scientific understanding, such compounds should be handled with caution to prevent them from causing serious harm to the environment and human health.