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2-Fluoro-3-(Trifluoromethyl)Bromobenzene

2-Fluoro-3-(Trifluoromethyl)Bromobenzene

Hongda Chemical

    Specifications

    HS Code

    166358

    Chemical Formula C7H3BrF4
    Molecular Weight 257.00
    Appearance Liquid (usually)
    Boiling Point Around 155 - 157 °C
    Solubility In Water Low (hydrophobic due to fluorine and bromine groups)
    Solubility In Organic Solvents Soluble in common organic solvents like dichloromethane, toluene
    Vapor Pressure Low, due to relatively high molecular weight and halogenation

    As an accredited 2-Fluoro-3-(Trifluoromethyl)Bromobenzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing 100g of 2 - fluoro - 3 - (trifluoromethyl)bromobenzene packaged in a sealed glass bottle.
    Storage 2 - fluoro - 3 - (trifluoromethyl)bromobenzene should be stored in a cool, dry, well - ventilated area away from heat sources and open flames. Keep it in a tightly - sealed container to prevent vapor leakage. Store it separately from oxidizing agents and reactive chemicals. This helps maintain its chemical stability and reduces the risk of hazardous reactions.
    Shipping 2 - fluoro - 3 - (trifluoromethyl)bromobenzene is shipped in well - sealed, corrosion - resistant containers. Transport follows strict chemical safety regulations, ensuring proper handling to prevent spills and exposure during transit.
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    2-Fluoro-3-(Trifluoromethyl)Bromobenzene 2-Fluoro-3-(Trifluoromethyl)Bromobenzene
    General Information
    Historical Development
    History and Development of 2 - Fluoro - 3 - (Trifluoromethyl) Bromobenzene
    I have tried to study the technology of chemical industry. In the case of 2 - Fluoro - 3 - (Trifluoromethyl) Bromobenzene, I know that its development has not been achieved overnight. In the past, the method of organic synthesis was not refined, and such fluorohalogenated aromatics were difficult to produce. However, scholars have continued to study, and the basic halogenation reaction was initially used, and it was difficult to obtain it. The yield was quite low and there were many impurities.
    After the organic chemistry gradually emerged, the new catalytic system appeared, which slowed down the reaction conditions and improved the yield. Chemists have explored the reaction mechanism in depth and improved the path, making the synthesis of this compound gradually mature. From the initial exploration to the refinement of the method, 2-Fluoro-3- (Trifluoromethyl) Bromobenzene has gradually expanded its use in the fields of organic synthesis and materials science, contributing to the development of the chemical industry and becoming an indispensable raw material.
    Product Overview
    2-Fluoro-3- (trifluoromethyl) bromobenzene is an important product of our chemical research. Its color is clear and transparent, liquid-like, and has unique rationalization. Looking at its structure, fluorine, trifluoromethyl and bromine atoms are cleverly connected to the benzene ring, giving it extraordinary properties.
    This product is used in the field of organic synthesis and has a wide range of uses. It can be used as a key intermediate to create other complex organic compounds. With its active groups, it can undergo various reactions, such as nucleophilic substitution, coupling reactions, etc., to build novel molecular structures.
    When preparing, it is necessary to strictly control the reaction conditions, such as temperature, pressure, catalyst dosage, etc. There is a slight difference in the pool, or the decrease in yield and the increase in impurities. And when storing and transporting, we should also be cautious, because of its lively nature, in case of uncomfortable environment, or dangerous. In the process of research and development, I have always thought about the method of refinement, hoping to improve its preparation efficiency, expand its application scope, and contribute to the progress of chemical research.
    Physical & Chemical Properties
    2 - Fluoro - 3 - (Trifluoromethyl) Bromobenzene is an important chemical substance. Its physical properties are unique. Looking at its morphology, it often appears as a colorless to light yellow liquid at room temperature, with specific volatility and a special odor. Its boiling point and melting point have certain values, which are related to its state changes under different temperature conditions.
    In terms of chemical properties, the presence of fluorine, bromine and trifluoromethyl in this substance makes its chemical activity significant. The high electronegativity of fluorine atoms gives the molecule a special electron cloud distribution, which affects its chemical reactivity. The strong electron-absorbing properties of trifluoromethyl also make the substance exhibit unique chemical behaviors in many reactions such as nucleophilic substitution and electrophilic addition. Bromine atoms provide active checking points for many reactions, and can participate in various chemical transformations such as substitution reactions, which are widely used in the field of organic synthesis.
    Technical Specifications & Labeling
    There is now a product named 2 - Fluoro - 3 - (Trifluoromethyl) Bromobenzene. The investigation of process specifications and identification (product parameters) is related to the preparation, properties and quality of this substance.
    The preparation method requires precise steps. The ratio of raw materials and reaction conditions must be strictly controlled to obtain this pure product. Its properties have specific colors, flavors and states, and the stability varies under different environments.
    In terms of quality identification, its purity, impurity content and other parameters should be listed in detail. The purity needs to reach a specific standard, and the impurity cannot exceed the limit. In this way, we can obtain the essence of this product process specification and identification (product parameters) to ensure that it can be used smoothly and without error in various applications.
    Preparation Method
    To make 2 - Fluoro - 3 - (Trifluoromethyl) Bromobenzene, the raw materials and production process are the key. First, take an appropriate amount of fluorine-containing, bromine-containing and trifluoromethyl-containing compounds as raw materials, and put them into the reactor according to a certain ratio. At the beginning of the reaction, the temperature needs to be controlled in a specific range, and the temperature should be slowly raised according to the reaction process. This is the essence of the reaction step. At the same time, a reasonable catalytic mechanism is set up, and a high-efficiency catalyst is added to accelerate the reaction rate and improve the yield. After the reaction is completed, the impurities are removed through multiple purification processes to obtain pure 2 - Fluoro - 3 - (Trifluoromethyl) Bromobenzene. In this way, the desired product is prepared, and its quality and purity are guaranteed.
    Chemical Reactions & Modifications
    In recent years, 2 - Fluoro - 3 - (Trifluoromethyl) Bromobenzene has a lot of thinking about the reaction and properties of the chemical.
    At the beginning, the reaction was sought according to the usual method, but the yield was not good, and the side reaction was not common. The reason is that the activity of the cover reagent is not appropriate, and the conditions are not well controlled.
    Then think about the change, adjust the ratio of the reagent, and adjust the temperature and pressure. With a catalytic agent to accompany it, hope to improve its properties. After many tests, the fruit has improved. The yield gradually increases, and the side reaction also decreases.
    It can be seen that the reaction of the chemical is not static, and the conditions must be adjusted skillfully according to the nature of the substance. In the research of 2 - Fluoro - 3 - (Trifluoromethyl) Bromobenzene, we should also follow this path, constantly thinking about change, seeking its transformation to be the best, and the best of nature.
    Synonyms & Product Names
    Today there is a thing called 2 - Fluoro - 3 - (Trifluoromethyl) Bromobenzene. Although its name is complex, it is crucial for those who study chemistry in my country.
    This substance is unique. It is also known by its synonymous name. Or because of its specific structure, or because of its use, it is called differently to express it. The names of commodities are also slightly different due to different production and sales.
    Observing the things of the past, they are all called by their characteristics. This 2 - Fluoro - 3 - (Trifluoromethyl) Bromobenzene, in the field of chemistry, has also been given synonymous names and commodity names due to its own characteristics. Although the names are different, they refer to the same thing. When we study them, we must scrutinize the similarities and differences of their names in order to clarify their nature, use them in reality, and promote the progress of chemistry.
    Safety & Operational Standards
    2-Fluoro-3- (trifluoromethyl) bromobenzene, this chemical substance, is related to safety and operating standards, and is essential.
    In preparation and use, procedures must be followed. First, the preparation site should be well ventilated to ensure that the toxic gas does not polymerize. All kinds of instruments must be clean and intact to prevent impurities from mixing in, causing bad reactions, and avoiding the risk of damage to the instrument and leakage.
    During preparation, the control of the dose of the drug is the key. According to the precise ratio, the reactants should not be slightly different. The reaction temperature and time must also be strictly monitored. If the temperature is too high, or the reaction is too fast, it will cause the risk of flushing; if the time is short, the product will be impure.
    When taking it, it must be well protected. Wear special gloves, the material must be resistant to corrosion of this chemical; wear protective clothing to prevent it from contaminating the skin. Goggles are also indispensable to prevent it from splashing into the eyes and causing serious damage to the eyes.
    When storing, choose an airtight container to avoid contact with air and water vapor. Keep it in a cool and dry place away from fire and heat sources to prevent decomposition or explosion.
    During handling, handle it with care to avoid collision and damage to the container. If there is a leak, immediately initiate emergency measures. Small leaks should be covered with inert materials such as sand, collected carefully, and disposed of properly; if there are large leaks, evacuate personnel immediately, report them to the relevant, and clean up according to professional guidance.
    The operation of this chemical is slightly careless, which may endanger people or pollute the environment. Therefore, every step should follow safety and operating standards to ensure safety.
    Application Area
    2 - Fluoro - 3 - (Trifluoromethyl) Bromobenzene is an important chemical substance. Its application field is quite wide. In the field of pharmaceutical synthesis, it can be used as a key intermediate to help create new specific drugs. With its unique chemical structure, it may improve the affinity and selectivity of drugs to specific targets, bringing hope to overcome difficult diseases. In the field of materials science, this substance can be used to prepare functional materials with special properties. For example, materials with excellent optoelectronic properties are expected to be applied to advanced display technology, optoelectronic devices, and improve product performance and stability. In addition, in the fine chemical industry, it can be used as a raw material for the synthesis of high-end fine chemicals, giving products unique chemical properties, meeting the stringent needs of high-end manufacturing for special chemicals, and promoting the innovative development of related industries.
    Research & Development
    In recent years, I have focused on the research of 2 - Fluoro - 3 - (Trifluoromethyl) Bromobenzene. This compound has unique properties and great potential in the field of organic synthesis.
    At the beginning, I explored the method of its preparation, but it has been subject to many twists and turns. If the ratio of raw materials and reaction conditions are slightly poor, it is difficult to meet expectations. However, I adhere to the heart of research and make unremitting attempts to optimize the method and improve the yield and purity.
    Then, consider its application and expansion. After repeated experiments, it was found that it has unique advantages in the synthesis of pharmaceutical intermediates and can provide key assistance for the development of new drugs. I also discussed with colleagues and exchanged experiences, hoping to widely apply this achievement and promote the development of the industry. The research and development of this compound still has a long way to go. I should persevere and make every effort to advance the field of chemistry.
    Toxicity Research
    Today there is a substance named 2 - Fluoro - 3 - (Trifluoromethyl) Bromobenzene. We investigate this substance in detail for the purpose of toxicity research.
    To observe its structure, it contains atoms such as fluorine and bromine, or it has special chemical properties. The activity of fluorine is strong, or it affects the stability and reactivity of this substance; bromine also has its own characteristics, both coexist, or cause unique toxicity.
    From an experimental point of view, under a specific environment, this substance interacts with certain substances or releases toxic components. In biological testing, the tested organism has abnormal reactions or damages its physiological functions, such as interfering with metabolism and injuring its cells and tissues.
    However, the investigation of toxicity is not achieved overnight. It is still necessary to apply multiple methods, considering the dose, exposure time and method, etc. It is hoped to know its toxicity in detail, provide evidence for protection and application, avoid its harm and use it for its benefit, and ensure the safety of people and the environment.
    Future Prospects
    The author of 2 - Fluoro - 3 - (Trifluoromethyl) Bromobenzene is a new material for chemical processing. I am currently researching it, but it has not yet been developed, so I can look forward to it.
    This physical property may be of great use in multiple domains. For example, in research, or it can be used to make special effects, saving patients and settling diseases. In the field of materials, or helping to develop new materials, to meet the needs of all walks of life.
    And the method of its synthesis is refined every day. It will certainly be able to reduce its cost and increase its quantity. In this way, it can be widely used and promoted. We are diligent in our research, and we will be able to develop its capabilities in the future, making it beneficial to the world.
    Where to Buy 2-Fluoro-3-(Trifluoromethyl)Bromobenzene in China?
    As a trusted 2-Fluoro-3-(Trifluoromethyl)Bromobenzene manufacturer, we deliver: Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements. Technical Excellence: Precision-engineered solutions backed by R&D expertise, from formulation to end-to-end delivery. Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.
    Frequently Asked Questions

    As a leading 2-Fluoro-3-(Trifluoromethyl)Bromobenzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

    What are the main uses of 2-Fluoro-3- (Trifluoromethyl) Bromobenzene?
    2-Fluoro-3- (trifluoromethyl) bromobenzene is also an organic compound. It has a wide range of uses and is often a key intermediate in the field of organic synthesis.
    First, it can be used as a starting material in the creation of new medicines. Because of its unique structure, it can introduce specific functional groups to build a molecular structure with biological activity. Through a series of reactions, it can prepare drugs for specific diseases, such as anti-tumor and antiviral agents. By its precise action with biological targets, it can achieve the purpose of treating diseases.
    Second, it also plays an important role in the research and development of pesticides. It can be chemically modified to derive compounds with high insecticidal, bactericidal or herbicidal properties. Such pesticides can precisely act on the physiological processes of pests, and are relatively friendly to the environment, contributing to the sustainable development of agriculture.
    Third, in the field of materials science, it can be used to synthesize polymer materials with special functions. Its fluorine-containing structure endows the material with unique physical and chemical properties, such as improving the weather resistance, corrosion resistance and low surface energy of the material. Or applied to coatings, plastics and other materials to improve the quality and performance of materials and meet the needs of different industrial scenarios.
    Fourth, as a building block for organic synthesis, chemists can use it to perform various reactions, such as palladium-catalyzed coupling reactions, combined with different organic reagents, to construct complex and diverse organic molecular structures, expand the boundaries of organic synthesis, and provide possibilities for the creation of new compounds.
    What are the physical properties of 2-Fluoro-3- (Trifluoromethyl) Bromobenzene?
    2-Fluoro-3- (trifluoromethyl) bromobenzene is one of the organic compounds. Its physical properties are unique and related to many aspects.
    First appearance, under normal temperature and pressure, it is often colorless to light yellow transparent liquid, clear and with a certain fluidity. It looks like smart water, but not pure water.
    The second and boiling point are about a specific temperature range. This temperature makes the substance change from liquid to gaseous. Generally speaking, the value of its boiling point varies slightly due to external pressure, but it is roughly within a certain range. The energy required to gasify the substance is specific, which is the embodiment of the intermolecular force.
    In addition to the melting point, when a certain low temperature is reached, the substance gradually solidifies from liquid to solid. This melting point is also its inherent physical property, which is the key to defining its physical state at different temperatures.
    In terms of density, it is slightly heavier than water. It is placed in water and often sinks at the bottom. Due to its molecular weight and structure arrangement, the mass of the substance contained in the unit volume is relatively large.
    Solubility is also an important property. In organic solvents, such as common ethanol, ether, etc., it often has good solubility and can be miscible with it, just like water emulsion. However, in water, the solubility is not good. Due to the large difference between the polarity of the substance and the polarity of the water molecule, the two are difficult to dissolve, just like the relationship between oil and water.
    In addition, its volatility is moderate, and it can evaporate slowly in the air, emitting a specific odor. Although it is not strong and pungent, it has its own unique smell, and it is also caused by the thermal movement and vapor pressure of its molecules. All these physical properties are key factors in organic synthesis, chemical production and other fields, which determine its application and processing methods.
    What are the synthesis methods of 2-Fluoro-3- (Trifluoromethyl) Bromobenzene?
    There are many different methods for preparing 2-fluoro-3- (trifluoromethyl) bromobenzene. One method is to use fluorine-containing and trifluoromethyl-containing benzene as the starting material, and introduce bromine atoms by halogenation. In this method, suitable fluorine-containing and trifluoromethylbenzene derivatives are selected first, and their structure and functional group activity have a great influence on the reaction process. Then, a halogenating agent, such as bromine or other suitable brominating agents, is selected, and the reaction temperature, time and solvent need to be adjusted depending on the reaction conditions and substrate characteristics. Usually, the reaction is mild and effective in specific solvents, such as halogenated hydrocarbons, or in the presence of catalysts.
    Another method can start from benzene with different substituents and gradually introduce fluorine, trifluoromethyl and bromo groups. For example, trifluoromethyl is first introduced as a benzene derivative, and trifluoromethyl is connected to the benzene ring through a suitable reaction, such as nucleophilic substitution or free radical substitution reaction. Then, by fluorination reaction, fluorine atoms are introduced. This step requires highly selective fluorination reagents and suitable reaction conditions to achieve the introduction of fluorine atoms at specific positions. Finally, a bromination reaction is carried out to obtain the target product 2-fluoro-3- (trifluoromethyl) bromobenzene.
    Preparation methods have their own advantages and disadvantages. The former is directly halogenated with a specific starting material, and the steps are simple, but the acquisition of the starting material may require trouble. Although the latter has complex steps, the selectivity and controllability of each step of the reaction are good, and the target molecular structure can be accurately constructed according to demand. When preparing, it is necessary to study the reaction conditions in detail, consider the cost of raw materials, yield and product purity, and obtain an effective synthesis path.
    What to pay attention to when storing 2-Fluoro-3- (Trifluoromethyl) Bromobenzene
    2-Fluoro-3- (trifluoromethyl) bromobenzene is an organic compound, and many things should be paid attention to when storing.
    The first choice of environment. When placed in a cool place, the compound can easily change its stability due to heat, or cause danger. If it is overheated, or causes a chemical reaction to get out of control, and even generates heat and gas, causing the pressure of the container to rise sharply, there is a risk of explosion. And it should be stored dry, away from a humid place. Due to moisture or reaction with the compound, it will deteriorate, affecting the quality and performance.
    The second is the choice of the container. When using a container with good sealing performance to prevent leakage. Because of its volatility, if it is not well sealed and escapes in the air, it will damage the environment on the one hand, and change the concentration due to volatilization on the other, which will affect subsequent use. In addition, the material of the container is also important, and it is necessary not to chemically react with the compound, such as some metal materials or react with fluorine-containing compounds. Therefore, suitable glass or specific plastic containers should be selected.
    Furthermore, it is necessary to keep away from fire sources and oxidants. This compound is flammable and difficult to control when exposed to an open flame or hot topic. Contact with oxidants can easily cause severe oxidation reactions, or serious consequences such as combustion and explosion.
    In addition, the storage area should be well ventilated. If it evaporates in a closed space and accumulates to a certain concentration, it is at risk of ignition or explosion in case of open flame or static electricity. Ventilation can disperse the volatile gas in time, reduce its concentration in the air, and ensure environmental safety.
    In addition, obvious warning signs should be set up at the storage place to make contacts aware of its danger and pay more attention during operation. Managers should also check regularly to see if the packaging is damaged or leaked. If there is any abnormality, they should dispose of it quickly and properly. In this way, the storage of 2-fluoro-3- (trifluoromethyl) bromobenzene is guaranteed to be safe.
    What is the market price of 2-Fluoro-3- (Trifluoromethyl) Bromobenzene?
    What you are inquiring about is the approximate market price of 2-fluoro-3- (trifluoromethyl) bromobenzene. However, the price of this chemical is difficult to sum up in a single word, due to many factors.
    The first person to bear the brunt is the state of market supply and demand. If the demand for this product is strong and the supply is limited, the price will rise; conversely, if the supply exceeds the demand, the price may decline. If there is a certain type of scarce chemical raw material in the market, the price will be high if there is a lot of demand.
    Furthermore, the cost of production is also the key. The price of raw materials, the simplicity of the production process, and the amount of energy consumption all affect the cost. If the raw materials are rare and expensive, the process is complicated and requires a lot of manpower and material resources. The cost is high and the price is not cheap.
    There are other brand and quality factors. Produced by well-known large factories, the quality is high, the inspection is strict, and the price may be higher than that of ordinary manufacturers. For example, the appliances made by Seiko are more expensive than ordinary ones, because the quality is better.
    In addition, the unique regions also have price differences. Different places have different transportation costs and tax policies. Coastal and inland, prosperous cities and remote places, prices may vary.
    As for the exact price, it is difficult to give. For more information, please consult chemical product distributors, trading platforms, or relevant manufacturers, who can provide you with more accurate prices based on current market conditions.