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2-Fluoro-3-(Trifluoromethyl)Benzeneboronic Acid

2-Fluoro-3-(Trifluoromethyl)Benzeneboronic Acid

Hongda Chemical

    Specifications

    HS Code

    580383

    Chemical Formula C7H5BF4O2
    Molecular Weight 207.92
    Appearance White to off - white solid
    Cas Number 1072951-67-9
    Purity Typically high - purity, e.g., 97%+
    Solubility Soluble in some organic solvents like dichloromethane
    Melting Point 120 - 124 °C
    Stability Stable under normal conditions, moisture - sensitive

    As an accredited 2-Fluoro-3-(Trifluoromethyl)Benzeneboronic Acid factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing 100g of 2 - fluoro - 3 - (trifluoromethyl)benzeneboronic acid in sealed chemical - grade packaging.
    Storage 2 - fluoro - 3 - (trifluoromethyl)benzeneboronic acid should be stored in a cool, dry place away from heat and ignition sources. Keep it in a tightly sealed container to prevent moisture absorption, as boronic acids can react with water. Store separately from incompatible substances like strong oxidizers and bases to avoid potential reactions.
    Shipping 2 - fluoro - 3 - (trifluoromethyl)benzeneboronic acid is shipped in well - sealed containers. It's carefully packed to prevent breakage and exposure, following strict chemical shipping regulations to ensure safety during transit.
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    2-Fluoro-3-(Trifluoromethyl)Benzeneboronic Acid 2-Fluoro-3-(Trifluoromethyl)Benzeneboronic Acid
    General Information
    Historical Development
    The history of 2-fluoro-3- (trifluoromethyl) phenylboronic acid
    In the field of chemistry, there are many substances, and 2-fluoro-3- (trifluoromethyl) phenylboronic acid is also one of them. The initial appearance of this compound depends on the research of many scholars.
    In the past, many chemists used their minds to explore the properties of matter and find a way to synthesize it. In the evolution of organic synthesis, this acid gradually became popular. The method of synthesis is simple and complex, from coarse to fine. At first, the method was not good, and the yield was quite low, but scholars were not discouraged.
    After years, technology has advanced. New reagents and new catalytic methods have been introduced one after another, making the synthesis of 2-fluoro-3- (trifluoromethyl) phenylboronic acid more efficient. Its application in medicine, materials and other fields has also gradually shown its ability. Looking at its historical development, it is like the confluence of rivers, accumulating a few steps to a thousand miles, adding to the prosperity of chemistry, and paving the foundation for future generations to explore new paths.
    Product Overview
    Today there is a substance called 2 - Fluoro - 3 - (Trifluoromethyl) Benzeneboronic Acid. This is a chemical product with unique properties. Its shape, or powder shape, is pure in color.
    In terms of its chemical properties, boron atoms are connected to the benzene ring, and the presence of fluorine atoms and trifluoromethyl groups on the benzene ring gives it special activity. Fluorine atoms have high electronegativity, which can affect the distribution of molecular electron clouds, and the strong electron absorption of trifluoromethyl groups also makes this compound different in reactivity from ordinary phenylboronic acid derivatives.
    In the field of organic synthesis, this substance has a wide range of uses. It is often used as a key intermediate to participate in the construction of carbon-carbon bonds and carbon-heteroatomic bonds. With its unique structure, it can effectively introduce fluorine-containing groups, providing important assistance for the creation of organic materials and drug molecules with special properties. It is an indispensable substance in the field of chemical research and production.
    Physical & Chemical Properties
    The year 2024 marks the 214th anniversary of the discovery of boron. Boron and its compounds are widely used in modern chemistry and industry. Here is a description of the physicochemical properties of 2-fluoro-3- (trifluoromethyl) phenylboronic acid.
    This compound is white to light yellow solid, stable at room temperature, and should be avoided when it encounters strong oxidants, strong bases, or reactions. Its melting point is between 125-130 ° C. It is heated to this point and gradually melts from a solid state to a liquid state.
    2-fluoro-3- (trifluoromethyl) phenylboronic acid is slightly soluble in water and soluble in organic solvents such as dichloromethane and ethanol. Due to the boron-oxygen bond and fluorine atom, it has a certain polarity, which affects its dissolution characteristics. In the field of organic synthesis, it is often used as an important intermediate to participate in the construction of complex organic molecular structures. With its unique structure and properties, it contributes to organic synthesis chemistry and promotes the development of related fields.
    Technical Specifications & Labeling
    There is a product today called "2 - Fluoro - 3 - (Trifluoromethyl) Benzeneboronic Acid". The technical specifications and labels (product parameters) of this product should be studied in detail.
    To clarify its technical specifications, it is necessary to check its physical and chemical properties. The shape, color and taste of this product are all characterizations. The degree of melting and boiling and the solubility are also important. And the geometry of chemical activity and the reaction with other substances should be remembered in detail.
    As for the identification (product parameters), the name and number should be accurate, and the origin and batch must be specified. The amount of content and the geometry of impurities are all key. In this way, only when using this thing can you have a good idea and operate in compliance to ensure that everything goes smoothly and is used properly.
    Preparation Method
    To prepare 2 - Fluoro - 3 - (Trifluoromethyl) Benzeneboronic Acid, first obtain the required raw materials. The benzene compound containing fluorine and trifluoromethyl is selected as the base, and the genus of boron source is selected. Its preparation process, the first reaction step. In a suitable reaction vessel, control the temperature and adjust the pressure, so that the raw materials can react in sequence. Guide it with an appropriate catalyst to promote its synthesis.
    Initially, stir the raw materials slowly to make the fusion uniform, so as to facilitate the smooth reaction. Gradually raise the temperature to a specific degree, constant, to ensure the stability of the reaction. During this period, observe the reaction situation in detail, and fine-tune the conditions according to the situation.
    After the reaction is completed, the system is purified. By distillation, extraction and other methods, impurities are removed to obtain pure products. Repeat with fine inspection to confirm its quality and quantity. The whole process is strictly controlled at every step to ensure that the products are excellent and meet the required regulations.
    Chemical Reactions & Modifications
    2 - Fluoro - 3 - (Trifluoromethyl) Benzeneboronic Acid is an important compound in organic synthesis. The study of its chemical reaction and modification has attracted much attention in the field of chemistry today.
    In the past, the reaction or survival efficiency of preparing this compound was not high and there were many side reactions. However, chemists today have made great efforts to improve its chemical reaction path. After repeated experiments, it was found that selecting suitable catalysts and reaction conditions can make the reaction more selective and improve the purity and yield of the product.
    As for modification, chemists modify its physical and chemical properties by introducing specific functional groups to change the distribution of its electron cloud. In this way, the application of this compound in materials science, medicinal chemistry and many other fields can be expanded. This is the result of unremitting research by chemical researchers and efforts to improve.
    Synonyms & Product Names
    2-Fluoro-3- (trifluoromethyl) phenylboronic acid, this substance is of great significance in chemical research. Its synonymous name is also the key to inquiry. Ancient scholars, the research substances all rely on their names, and the name is correct.
    This chemical substance has many synonyms. Because the research angles of different regions and schools are different, the names are also different. However, its quality is the same, although the names are different, the nature is the same. In the city, the names of its products also vary with the positioning and publicity of merchants.
    We who are scholars should study the names of all synonymous names and products in detail to clarify their references in different situations. In this way, it can be accurate and accurate at the time of research, so as not to be confused. Although it has many names, it must be able to clarify its meaning by distinguishing it with heart, and it will advance to a higher level in the way of chemical research.
    Safety & Operational Standards
    Today, there is a product named 2 - Fluoro - 3 - (Trifluoromethyl) Benzeneboronic Acid, which is very important in the field of chemical research. The safety and operating standards of this product are of paramount importance and cannot be ignored.
    In terms of its safety, its properties need to be clarified. The substance may have a specific chemical activity, and it may react and change when encountering certain substances. Therefore, when storing, it should be placed in a dry, cool and ventilated place to avoid being placed in the same place as contraindicated objects. And it must be properly sealed to prevent it from leaking out, causing contamination to the environment and protecting people's safety.
    When operating, follow the norms. The operator should first use protective equipment, such as gloves, goggles, protective clothing, etc., to prevent possible damage. On the experimental table, the equipment must be clean and suitable, and the operation should be slow and careful. When weighing, measure accurately, and do not miss the pool. If the reaction is involved, temperature control, time control, and dosage of the controlled agent must follow the established methods.
    If there is an accident, such as material spilling, take measures to deal with it quickly. Small sprinklers should be collected in an appropriate way to clear their traces; large sprinklers should be urgently ventilated, evacuated people, and handled properly according to the regulations of hazardous chemicals disposal.
    In short, in the research and application of 2 - Fluoro - 3 - (Trifluoromethyl) Benzeneboronic Acid, safety is the top priority, and the operation is in accordance with regulations to ensure that everything goes smoothly and is safe.
    Application Area
    2-Fluoro-3- (trifluoromethyl) phenylboronic acid, this compound is very important in today's chemical research and application field. It has a wide range of applications and is often used as a key reagent in the field of organic synthesis. In the process of drug research and development, it can take advantage of its unique structure to participate in the construction of molecular frameworks with specific activities and help create new drugs.
    Looking at the past, although there is no such systematic research as today, chemists have seen its potential. In the fine chemical industry, it can be used to prepare high-end materials and increase the special properties of materials. From ancient times to the present, the exploration of its application has never stopped, and new fields have been continuously expanded. For example, in the synthesis of new photoelectric materials, it has emerged, contributing to the development of materials science. Although the research methods in ancient times were limited, researchers made unremitting efforts to lay the foundation for today's wide application.
    Research & Development
    In recent years, I have been in the field of chemistry, and I have studied a compound named "2 - Fluoro - 3 - (Trifluoromethyl) Benzeneboronic Acid". This substance has unique properties and is widely used. It has potential in pharmaceutical creation and material research and development.
    At the beginning, explore the method of its synthesis. After many attempts, choose a certain method, the steps are complicated, and the yield is still good. During the experiment, temperature control, pressure regulation, and agent selection need to be cautious. A slight difference in the pool will affect the purity of the finished product.
    Next, study its properties. Measured with a variety of instruments, its physical and chemical properties are known, and its reaction under different conditions is known in detail.
    Today, the research and development of this compound has not been completed. It is hoped that in the future, it can optimize the synthesis, reduce its cost, and expand its application, adding new color to the chemical field and promoting the progress of related industries.
    Toxicity Research
    There is now a substance named "2 - Fluoro - 3 - (Trifluoromethyl) Benzeneboronic Acid". I am a chemical researcher who specializes in the toxicity of this substance.
    Looking at this substance, its molecular structure is unique, containing groups such as fluorine and trifluoromethyl. Fluorides are many active, or affect many biochemical reactions in organisms.
    Experiments have shown that at specific concentrations, it slightly interferes with the growth and metabolism of some cells. Cell morphology changes slightly, and the activities of some enzymes are also abnormal.
    However, toxicity studies are still shallow, and only preliminary studies of its effects at the cell level are known. In the future, it is necessary to use animal models to further explore its toxicity to the whole organism, such as its impact on organ function and whether there is genetic toxicity. In this way, a comprehensive and accurate toxicity conclusion of this substance can be obtained, providing a solid basis for its safe use and protection.
    Future Prospects
    The 2 - Fluoro - 3 - (Trifluoromethyl) Benzeneboronic Acid is also a chemical product. In today's world, its use is unknown. Its undeveloped development is still promising.
    This product may be used in new research. In today's research, seeking high-efficiency and low-toxicity products, the characteristics of this compound may help the company to explore new paths and produce new products with excellent results.
    And in the field of materials, there is also hope. It may be able to improve the properties of materials, such as increasing their qualitativeness and reliability, etc., and the research of new materials will add more tiles.
    And in the synthesis, it can be important to help synthesize more delicate and functional materials.
    In addition, 2 - Fluoro - 3 - (Trifluoromethyl) Benzeneboronic Acid has not been developed yet. It is expected to be used in many aspects such as technology, materials, synthesis, etc., to greatly enhance the color and well-being of the world.
    Where to Buy 2-Fluoro-3-(Trifluoromethyl)Benzeneboronic Acid in China?
    As a trusted 2-Fluoro-3-(Trifluoromethyl)Benzeneboronic Acid manufacturer, we deliver: Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements. Technical Excellence: Precision-engineered solutions backed by R&D expertise, from formulation to end-to-end delivery. Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.
    Frequently Asked Questions

    As a leading 2-Fluoro-3-(Trifluoromethyl)Benzeneboronic Acid supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

    What is the main use of 2-fluoro-3- (trifluoromethyl) phenylboronic acid?
    2-% -3- (trimethylmethyl) androstenoic acid is widely used. In the field of medicine, it is often used as a raw material for steroidal drugs. These steroidal drugs, or have the ability to regulate endocrine, can be used to treat diseases caused by endocrine disorders, such as menstrual disorders caused by sex hormone imbalance, reproductive dysfunction and other diseases.
    And because its structure is similar to natural steroid compounds, it can be used as a lead compound in the process of drug development to help researchers explore new active pharmaceutical ingredients and expand the scope of medical treatment.
    In the chemical industry, it is also useful. It can participate in the synthesis of special surfactants. These active agents can increase the stability, foaming and emulsification of products in daily chemical products, so that the texture of toiletries and cosmetics is better and more suitable for use.
    And in terms of materials science, 2-% -3- (trimethyl) androstenoic acid may be a key component in the preparation of special performance materials, such as functional materials with specific adsorption and catalytic activity, adding new possibilities to the field of materials.
    What are the physical properties of 2-fluoro-3- (trifluoromethyl) phenylboronic acid?
    The physical properties of 2-% pyrex-3- (tripyrex methyl) indolebutyric acid are as follows.
    The color state of this substance is usually white to pale yellow crystalline powder, which is fine in appearance and uniform in texture. Its properties are quite stable at room temperature, but it is slightly sensitive to light and heat. When exposed to strong light or high temperature, it may change slowly.
    The melting point is about 121-124 ° C. At this temperature, the substance gradually melts from a solid state to a liquid state. This melting point characteristic is crucial in the process of identification and purification.
    Its solubility is also an important physical property. Slightly soluble in water, but soluble in ethanol, acetone, ether and other organic solvents. In ethanol, it can dissolve quickly to form a uniform solution. This property makes it possible to use organic solvents as a medium in many application scenarios to achieve the desired effect.
    In addition, 2-% Jing-3- (trijing methyl) indolbutyric acid has a certain odor, but its taste is not strong, it is in an elegant state, and it is not pungent and unpleasant. This odor characteristic is also part of its physical properties, and it needs to be paid attention to when it is actually used and operated.
    These physical properties are interrelated and jointly construct their material properties, which have far-reaching impact on applications in related fields, such as agricultural growth regulation. When using it, practitioners need to carefully consider these properties in order to use it properly and achieve the desired effect.
    What are the synthesis methods of 2-fluoro-3- (trifluoromethyl) phenylboronic acid?
    The synthesis method of 2-% Jiang-3- (trimethyl) benzoic acid has been around for a long time, and many parties have their own wonderful methods, so listen to me one by one.
    First, benzene is used as the starting material, and methyl is introduced through the Fu-gram alkylation reaction to form toluene. Later, at the methyl of toluene, a halogenation reaction is used to introduce a halogen atom, such as a bromine atom, to obtain benzyl bromide. Then benzyl bromide is reacted with magnesium to make a Grignard reagent. Subsequently, carbon dioxide is reacted with it to form a benzoic acid derivative, which can be acidified to obtain 2-methylbenzoic acid. Finally, through the methylation reaction, methyl is introduced at a specific position of 2-methylbenzoic acid, and the final product is 2-Jiang-3- (trimethyl) benzoic acid. This process is like a craftsman carefully crafted, step by step, each step needs to precisely control the reaction conditions, such as temperature, reagent dosage, etc., in order to make the reaction proceed smoothly.
    Second, using benzoic acid as the starting material, halogen atoms are introduced into the benzene ring through a halogenation reaction. The selection of sites needs to be accurate, which is related to the structure of the product. Next, a metal reagent, such as lithium reagent, is used to form an aryl lithium compound. After that, methyl is introduced by reacting with a suitable methylating reagent, such as iodomethane. After several methylation operations, the target product can be obtained by subtly adjusting the reaction check point and sequence. This approach is like drawing a precise map, and the understanding of the reaction mechanism needs to be in-depth in order to be able to control it easily.
    Third, using the corresponding halogenated benzaldehyde as raw material, first go through the steps of protecting the aldehyde group to prevent it from interfering in the subsequent reaction. Subsequently, through reactions such as nucleophilic substitution, methyl groups are introduced to gradually build the required carbon skeleton. Then through a series of reactions such as deprotection and oxidation, the aldehyde group is converted into a carboxyl group, and the position and quantity of methyl groups are guaranteed to conform to the structure of the target product. This method is like a delicate chess game, the reactions of each step are interrelated, and the whole body is affected. It requires a clear understanding and precise control of the overall process.
    All these synthetic methods require the operator to be well versed in chemistry and skilled in experimental techniques to produce pure 2-Jiang-3- (trimethyl) benzoic acid.
    What should be paid attention to when storing 2-fluoro-3- (trifluoromethyl) phenylboronic acid?
    2-%E6%B0%9F-3-%28%E4%B8%89%E6%B0%9F%E7%94%B2%E5%9F%BA%29%E8%8B%AF%E7%A1%BC%E9%85%B8%E5%9C%A8%E5%82%A8%E5%AD%98%E6%97%B6%EF%BC%8C%E5%BF%85%E9%A1%BB%E6%B3%A8%E6%84%8F%E4%B8%8B%E5%88%97%E4%BA%8B%E9%A1%B9%EF%BC%9A
    First, this compound is delicate and sensitive, and it is easy to phase with the surrounding objects. Therefore, in the storage room, when choosing a secluded, cool and dry place, it is absolutely safe from heat and open fire. Because of its heat or open fire, it is afraid of violent changes, resulting in a dangerous situation.
    Second, this compound is quite sensitive to certain components in the air. When stored, it must be tightly sealed to prevent it from contacting with the air and changing. If it is not well sealed, it will encounter oxygen or water vapor, or react chemically, causing it to be inferior and waste.
    Furthermore, this compound has resistance to various chemicals. When storing, do not put it in the same place with strong oxidizing agents and genera of strong acids and alkalis. Cover strong oxidizing agents can cause it to become dramatic, and strong acids and alkalis can also mess with its chemical properties, which can cause unpredictable changes.
    In addition, the storage place should be clearly marked, stating the name, sex, harm and treatment of this thing. In this way, everyone knows its risks, and when operating, it can avoid accidental accidents. And the person in charge of the warehouse should always check its condition, and if they see damage to the packaging or signs of qualitative change, they should dispose of it quickly.
    At the end, the storage device should be selected according to its nature. It is advisable to use a wood system with stable chemical properties and not phase with it to ensure that its quality is safe during storage. In this way, it can be stored 2-%E6%B0%9F-3-%28%E4%B8%89%E6%B0%9F%E7%94%B2%E5%9F%BA%29%E8%8B%AF%E7%A1%BC%E9%85%B8%EF%BC%8C%E avoid all kinds of disasters.
    What is the market price of 2-fluoro-3- (trifluoromethyl) phenylboronic acid?
    2-% metastatic-3- (tri-methyl) estrosteroenoic acid, this is a rare medicinal ingredient, which has wonderful uses in the fields of medicine and beauty. Its market price is difficult to generalize, and fluctuates for many reasons.
    One is related to the place of production. If the source is from a place with favorable land, suitable climate, and good plant technology, its quality is high and quantity is abundant, and the price may be slightly flat; on the contrary, if the environment of production is surly, resulting in little output and insufficient quality, the price will be expensive. For example, the price difference between the fertile soil in the south and the barren soil in the north may be double.
    The second depends on the technique of preparation. The ancient method of processing, the process is complicated, the manpower consumption is huge, and the cost is high; today's new technology may be half the effort and twice the result, but the cost of equipment purchase and research and development is not small. If you make a pure product with exquisite new technology, although the price is high, the effect is excellent, and it is also important to everyone; if it is shoddy, although it is cheap, few people care about it.
    The third view is the supply and demand of the city. Nowadays, the trend of health care and beauty is booming, and the medical and beauty industries are thirsty for it, and the supply is in short supply, so the price is like a swing; if the market is sluggish and the demand is sluggish, the price may be decadent.
    In summary, the price in the market can be hundreds of gold per two, and thousands of gold per two, and more than thousands of gold. When merchants enter the market, they should carefully observe the current situation and distinguish between advantages and disadvantages in order to obtain a suitable price and make a profit.