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2-Fluoro-3-Methoxybenzeneboronic Acid

2-Fluoro-3-Methoxybenzeneboronic Acid

Hongda Chemical

Specifications

HS Code

477913

Chemical Formula C7H8BFO3
Molecular Weight 169.946 g/mol
Appearance Solid (usually white or off - white)
Purity Typically high - purity in commercial products, e.g., 95%+
Solubility In Water Slightly soluble
Solubility In Organic Solvents Soluble in common organic solvents like dichloromethane, ethyl acetate
Melting Point 125 - 130 °C (approximate, may vary)
Boiling Point Decomposes before boiling under normal pressure
Density Approx. 1.34 g/cm³ (estimated)

As an accredited 2-Fluoro-3-Methoxybenzeneboronic Acid factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

Packing & Storage
Packing 100g of 2 - fluoro - 3 - methoxybenzeneboronic acid in sealed, labeled chemical - grade packaging.
Storage 2 - fluoro - 3 - methoxybenzeneboronic acid should be stored in a cool, dry place. Keep it in a well - sealed container to prevent moisture absorption, as boronic acids can react with water. Store away from heat sources and incompatible substances like strong oxidizing agents. This helps maintain its chemical integrity and stability over time.
Shipping 2 - fluoro - 3 - methoxybenzeneboronic acid is shipped in well - sealed containers, compliant with chemical transport regulations. Packaged to prevent breakage and leakage, ensuring safe transit to its destination.
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2-Fluoro-3-Methoxybenzeneboronic Acid 2-Fluoro-3-Methoxybenzeneboronic Acid
General Information
Historical Development
In the past, there were those who studied chemistry, specializing in the study of one thing, named "2-Fluoro-3-Methoxybenzeneboronic Acid". The beginning of this thing first appeared in the research of all the sages. At that time, the masters tried their best to understand its nature and its use.
At the beginning, I only knew a little about it, and I was wrong in the method of synthesis. However, the scholars are unyielding, tired of trial and failure, tired of failure and tired of trial. After a long time, or change the method, or change the material, gradually gain something. The art of synthesis, from clumsy to clever; the clarity of character, from shallow to deep.
As for today, this "2 - Fluoro - 3 - Methoxybenzeneboronic Acid" is very useful in the fields of medicine and chemical industry. Looking at its process, it has started from the beginning, and through the efforts of many sages, it has finally become today's prosperity. It is a great advancement in chemical research.
Product Overview
Today there is a product called 2 - Fluoro - 3 - Methoxybenzeneboronic Acid. This is an important raw material for organic synthesis and has a wide range of uses in medicine, materials and other fields. Its properties are relatively stable, and its appearance is white to light yellow crystalline powder. It has the structure of fluorine atoms, methoxy groups and boric acid groups, which gives it specific chemical properties. Fluorine atoms enhance its lipophilicity and show special activity in organic reactions; methoxy groups affect the distribution of electron clouds and also play a role in reaction check points and activities; boric acid groups are often the key reaction check points in organic synthesis, and can participate in a variety of coupling reactions, laying the foundation for the construction of complex organic molecular structures. Due to its excellent structure and properties, it has attracted much attention in chemical synthesis research. Many chemists are dedicated to exploring its application potential to promote the development of related fields.
Physical & Chemical Properties
2 - Fluoro - 3 - Methoxybenzeneboronic Acid is an important organic compound. Its physical and chemical properties are unique and worthy of our detailed investigation.
Looking at its physical properties, at room temperature, this compound is often in a solid state with a specific melting point and boiling point. The value of the melting point is related to its phase transition. At a certain temperature, the solid state gradually melts into a liquid state. This temperature is the characterization of its melting point. The same is true for the boiling point. At a certain temperature, the liquid state will transform into a gaseous state.
As for the chemical properties, the presence of boron atoms in this compound gives it special reactivity. Boron atoms can participate in a variety of chemical reactions, such as reacting with nucleophiles to form new chemical bonds. Due to its fluorine and methoxy substituents, it also affects the distribution of its electron cloud, which in turn affects the selectivity and rate of its chemical reactions. This compound may be used as a key intermediate in the field of organic synthesis, assisting in the construction of many complex organic molecules.
Technical Specifications & Labeling
Today there is a product called 2 - Fluoro - 3 - Methoxybenzeneboronic Acid. It is my top priority to study the technical specifications and labels (commodity parameters) of this product.
Looking at this compound, its structure is unique. The fluorine atom and methoxy group are divided into specific positions of the benzene ring, and the boric acid group also has characteristics. In the technical specifications, it is necessary to clarify its purity, which is related to its quality. It must be measured by accurate methods, and it must be extremely high purity.
On the label, its name and chemical formula should be accurate, so that the viewer can understand its essence. In the commodity parameters, physical constants such as melting point and boiling point need to be recorded in detail to provide users with exact data. In this way, the essence of the technical specifications and labels of this object can be obtained to meet the needs of scientific research and production.
Preparation Method
This product of 2 - Fluoro - 3 - Methoxybenzeneboronic Acid, its raw materials and production process, reaction steps and catalytic mechanism are the key. The fluorinated anisole is taken as the starting material, and the halogen atom is introduced by halogenation. This is the initial step. Then, it meets the borate ester reagent, and undergoes a coupling reaction in a specific catalytic system, such as palladium catalysis, to connect the boron group to build the desired structure.
The reaction conditions need to be carefully controlled, and the choice of temperature and solvent is very important. If the temperature is too high or side reactions are caused, if it is too low, the reaction will be delayed. The polarity and solubility of the solvent are related to the dispersion of the reactants and the reaction process. In the catalytic mechanism, the palladium catalyst activates the reactant to promote the breaking and formation of bonds.
After separation and purification, impurities are removed to obtain a pure product. In this way, according to these steps, 2-Fluoro-3-Methoxybenzeneboronic Acid can be obtained, which is suitable for the desired quality.
Chemical Reactions & Modifications
Today there are 2 - Fluoro - 3 - Methoxybenzeneboronic Acid, which is the focus of our research in chemical reactions and modifications. Looking at its structure, fluorine and methoxy are attached to the benzene ring, and the boron group is also on the side.
Chemical reactions, or encounters with nucleophiles, on the benzene ring, the charge distribution is different, leading to changes in nucleophilic substitution. Boron group activity is quite good, or in the way of coupling, it forms new carbon-boron bonds with halogenated hydrocarbons, etc., to expand its molecular structure.
As for modification, it can increase its stability or adjust its solubility. In organic solvents, change its substituents to make them more suitable for specific needs. If it is replaced by a long-chain alkyl group or changed to its polarity, it can be used in the fields of drug delivery and material synthesis.
We should study this reaction and modification carefully, explore its laws, and find the best way to make 2-Fluoro-3-Methoxybenzeneboronic Acid used in various applications, develop its ability and create greater value.
Synonyms & Product Names
Today there is a thing called "2 - Fluoro - 3 - Methoxybenzeneboronic Acid". Although its name is different from common knowledge, it is very important in the field of my chemical research.
The synonymous name and trade name of this substance also need to be explored in detail. Synonyms are names named from different perspectives and according to different rules. Although the expressions are different, they actually refer to the same thing. Trade names are related to the market. In order to promote this thing, merchants use easy-to-remember and distinctive names.
For our researchers, understanding its synonyms and trade names can make academic exchanges smoother and market transactions more accurate. Exploring the synonyms and trade names of this "2 - Fluoro - 3 - Methoxybenzeneboronic Acid" is like seeking secrets, adding to the path of chemistry, making our understanding of it more comprehensive and in-depth.
Safety & Operational Standards
2 - Fluoro - 3 - Safe operation of Methoxybenzeneboronic Acid
2 - Fluoro - 3 - Methoxybenzeneboronic Acid is a compound commonly used in research. Safety is the first priority in this operation. Its storage should be placed in a dry, dry and well-ventilated place, and the source of ignition and oxidation. This is because the compound is exposed to open flame, high temperature or oxidation, and there is a risk of explosion.
During the operation process, it is necessary to take preventive measures. Wear appropriate anti-clothing, gloves and eyewear. If you accidentally touch the skin, wash it with a lot of running water immediately, and then treat it immediately; if you touch the eyes, quickly wash it with a lot of water or physiological water, and then immediately.
Furthermore, its use needs to follow the grid operation process. Take it and use dry and combined appliances to avoid mixing in. After finishing, the remaining 2 - Fluoro - 3 - Methoxybenzeneboronic Acid cannot be used. It should be properly handled according to the camera to prevent pollution.
In terms of reverse operation, it is necessary to control the reverse parts, such as degree, force and reaction. Due to the non-reverse parts, it may cause the reverse parts to go out of control and lead to safety accidents. In addition, the use of 2 - Fluoro - 3 - Methoxybenzeneboronic Acid, safe operation is of paramount importance, and must not be negligent.
Application Area
Today, there is a product named 2 - Fluoro - 3 - Methoxybenzeneboronic Acid, which has a wide range of application fields. In the field of pharmaceutical research and development, this substance is often a key raw material. Doctors and drug researchers, with its unique chemical properties, can make a variety of drugs, or cure diseases, or prevent diseases, with remarkable effects.
In the field of material science, it also has its own uses. It can participate in the synthesis of special materials, so that the material has different properties, such as enhancing its stability, improving its electrical and thermal conductivity, etc., to help the material continue to innovate.
Furthermore, in the field of organic synthesis, it is like a delicate key, opening the door to the synthesis of many complex compounds. Chemists have built novel organic molecules with their unique structures, contributing to the development of organic chemistry and driving the field forward.
Research & Development
In recent years, Yu devoted himself to the research of 2 - Fluoro - 3 - Methoxybenzeneboronic Acid. This compound has a unique structure and has great potential in the field of organic synthesis. At the beginning, there were many obstacles in the synthesis method, and the yield was not as satisfactory.
Then read the ancient books, refer to the methods of various families, and try again and again. After adjusting the reaction conditions many times, such as the ratio of temperature, solvent and catalyst, gradually obtained. The yield increased, and the quality became better.
During this period, the reaction mechanism was deeply analyzed, and the influence of various factors was understood. This research is not only to improve the yield, but also to expand its application. It is hoped to develop new synthetic paths and contribute to the development of organic chemistry. In the future, we should still move forward and tap its potential for long-term development.
Toxicity Research
Recently, the toxicity study of 2 - Fluoro - 3 - Methoxybenzeneboronic Acid is quite important. To distinguish the toxicity of various chemical substances, it is related to the safety of the user and the environment.
Taste this 2 - Fluoro - 3 - Methoxybenzeneboronic Acid, its molecular structure, or contains the cause of toxicity. With its chemical characteristics, it comes into contact with other substances, or undergoes aberration, and the toxin appears.
When experimenting, observe its effect on various organisms. Observe its effect on the genus of microinsects, plants and trees, or causes growth obstacles and loss of vitality. And it enters the water and soil, and it is also afraid of migrating to the environment and leaving a disaster to the ecology.
Therefore, in this study of the toxicity of 2-Fluoro-3-Methoxybenzeneboronic Acid, we should be cautious, examine its nature in detail, understand its harm, and think that the protection policy is to avoid disasters in the invisible, to protect the public from Kangtai, and to protect the peace of heaven and earth.
Future Prospects
Guanfu 2 - Fluoro - 3 - Methoxybenzeneboronic Acid This substance has unique properties and a wide range of uses. It has high hopes for future development.
In today's world, science and technology are changing with each passing day, and chemical research is also constantly improving. With its unique structure, this compound may emerge in the field of pharmaceutical synthesis, helping to create special drugs and save the suffering of the common people. In material science, it is also expected to provide key assistance for the research and development of new materials, so that the properties of materials can be better.
Our chemical researchers should uphold the determination and make unremitting exploration. With time, we will be able to explore its potential, make it shine in various fields, and make outstanding achievements for human well-being and social progress, so as to form a grand development vision for the future.
Where to Buy 2-Fluoro-3-Methoxybenzeneboronic Acid in China?
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Frequently Asked Questions

As a leading 2-Fluoro-3-Methoxybenzeneboronic Acid supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

What are the main uses of 2-Fluoro-3-Methoxybenzeneboronic Acid?
2-Fluoro-3-methoxyphenylboronic acid has a wide range of uses. In the field of organic synthesis, it is often used as a key intermediate. In the construction of complex organic molecular structures, through various reaction types such as Suzuki coupling reaction, it can be coupled with halogenated aromatics or olefin compounds, and then many compounds with special structures such as biphenyls or alkenylbenzene are formed. These products are of great significance in the fields of pharmaceutical chemistry and materials science.
In the process of drug development, compounds synthesized by such reactions may have unique physiological activities and can be used as lead compounds to lay the foundation for the creation of new drugs. For example, some biphenyl-structured drugs have shown good pharmacological efficacy in anti-tumor and anti-virus, and 2-fluoro-3-methoxyphenylboronic acid may play an indispensable role in this synthesis process.
In the field of materials science, functional materials prepared by Suzuki coupling reaction may have unique optoelectronic properties. For example, some organic optoelectronic materials containing biphenyl structure have emerged in the application of organic Light Emitting Diode (OLED), organic solar cells and other devices. 2-fluoro-3-methoxyphenylboronic acid is also an important starting material for the synthesis of such materials.
Furthermore, it is also useful in the preparation of fine chemicals. It can provide a key structural unit for the synthesis of fine chemicals such as fragrances and dyes with specific structures, and can be modified by a series of reactions to endow fine chemicals with unique properties and functions.
What are the physical properties of 2-Fluoro-3-Methoxybenzeneboronic Acid?
2-Fluoro-3-methoxyphenylboronic acid is a commonly used reagent in organic synthesis. Its physical properties are quite critical and it is widely used in the field of organic synthesis.
Looking at its properties, it is mostly white to off-white solids under normal conditions. This is due to the interaction between atoms in its molecular structure, resulting in the orderly arrangement of molecules to form a stable solid structure. Its melting point is within a certain range, which is determined by the intermolecular force. When heated, specific energy needs to be absorbed to overcome the attractive force between molecules, causing the lattice structure to disintegrate, resulting in a transition from solid to liquid.
Solubility is also an important physical property. In general, it has a certain solubility in common organic solvents such as dichloromethane and toluene. This is because the molecule of this substance has a certain polarity, and there are interaction forces with organic solvent molecules, such as van der Waals force, dipole-dipole interaction, etc., so that it can be dispersed in the solvent. In water, the solubility is relatively low, and due to the strong polarity of water molecules, the matching degree of force between 2-fluoro-3-methoxyphenylboronic acid molecules is not good.
Furthermore, its stability cannot be ignored. It is relatively stable under normal temperature and pressure and dry environment. In case of extreme conditions such as strong oxidants, strong acids and bases, the molecular structure may be affected, and a chemical reaction occurs. Due to the characteristics of the phenylboronic acid group, the boron atom has a certain electron deficiency, which is easy to react with nucleophiles. And the existence of fluorine atoms and methoxy groups will also affect the overall electron cloud distribution of the molecule, which has an effect on stability.
These physical properties are of great significance in the design of organic synthesis reactions, the selection of reaction conditions, and the separation and purification of products.
What are the synthetic methods of 2-Fluoro-3-Methoxybenzeneboronic Acid?
The synthesis method of 2-fluoro-3-methoxyphenylboronic acid has many paths, as follows.
First, it can be started from the corresponding halogenated aromatic hydrocarbon. Taking 2-fluoro-3-methoxybromobenzene as an example, in an anhydrous environment, tetrahydrofuran is used as a solvent, magnesium chips are added to form Grignard's reagent. This process needs to be carefully controlled temperature, so as not to make the reaction too violent. After passing into trimethyl borate, and then hydrolyzed, the target product 2-fluoro-3-methoxyphenylboronic acid can be obtained.
Second, 2-fluoro-3-methoxy iodobenzene can also be used as a raw material. In the presence of a palladium catalyst, it reacts with the diphenacol borate to form the corresponding borate ester intermediate. The choice of palladium catalyst is very critical, such as tetra (triphenylphosphine) palladium. The reaction conditions need to be precisely regulated, such as temperature and reaction time. Then the borate intermediate is hydrolyzed to obtain 2-fluoro-3-methoxy phenylboronic acid.
Furthermore, the guide group strategy can also be used. The guide group is introduced into the benzene ring to position the guide, so that the boration reaction selectively occurs at the desired position. The guide group is then removed through appropriate steps to obtain pure 2-fluoro-3-methoxyphenylboronic acid. Although this method is a little complicated, it has good selectivity and can effectively improve the purity and yield of the product.
There are many methods for synthesizing 2-fluoro-3-methoxyphenylboronic acid. The advantages and disadvantages of each method are mutually exclusive. The appropriate method should be carefully selected according to the actual situation, such as the availability of raw materials, cost considerations, and product purity requirements.
2-Fluoro-3-Methoxybenzeneboronic Acid need to pay attention to when storing
When storing 2-fluoro-3-methoxyphenylboronic acid, pay attention to various matters. This compound is delicate and prone to hydrolysis in contact with water, causing damage to its structure and properties. Therefore, it must be stored in a dry place, away from water vapor. A desiccant can be placed on the side of the reservoir to keep the environment dry.
Furthermore, it is quite sensitive to temperature. Under high temperature, it may cause decomposition and deterioration, which will damage its quality. It should be stored in a cool place, usually 2-8 ° C. If the conditions are not sufficient, it should also be controlled at room temperature and protected from heat sources.
Light is also key. This product is exposed to light, or photochemical reactions can cause changes in its composition. Be sure to store in a shading device, such as a brown bottle, to prevent light damage.
In addition, it needs to be isolated from oxidizing and reducing substances. Because of its boric acid structure, oxidation, reducing agent, or reaction will damage its chemistry. Materials with different chemical properties should be stored in different places to prevent interaction.
Also, the storage device should also be paid attention to. Improper material, or reaction with compounds, causing pollution. It is advisable to choose chemically stable devices, such as glass, specific plastic materials, and well sealed to avoid contact with air.
Proper storage of 2-fluoro-3-methoxyphenylboronic acid is essential to maintain its quality and chemical activity, and all conditions should be carefully controlled.
2-Fluoro-3-Methoxybenzeneboronic the market price of Acid
I look at the "2 - Fluoro - 3 - Methoxybenzeneboronic Acid" you are inquiring about. This is a chemical substance called 2 - Fluoro - 3 - Methoxyphenylboronic acid. Its market price varies due to many factors, and it is difficult to generalize.
First, purity is the key. If the purity is extremely high, it is almost perfect, and it reaches the level of scientific research, it is suitable for high-end experiments, and its price is high. Because the preparation of this high-purity product requires exquisite craftsmanship, many complicated steps, a lot of manpower, material resources and time, and high cost, the price is not cheap. On the contrary, if the purity is slightly lower, it is relatively easy to use for general industrial purposes.
Second, market supply and demand determine its price. If for a while, many chemical companies and scientific research institutions have a surging demand for this material, and the supply is limited, the supply is in short supply, and the price will rise. On the contrary, if the demand is low, the manufacturer produces too much output, and the supply exceeds the demand, the price will tend to fall.
Third, the manufacturer and brand also have an impact. A well-known large factory is famous for its exquisite craftsmanship, high-quality raw materials and strict quality control, and its product price may be higher than that of ordinary manufacturers. Although the price of a small factory may be low, the quality may be difficult to compare with that of a large factory.
Fourth, the purchase volume is also related to the price. If the one-time purchase volume is large, the manufacturer may give preferential discounts due to the idea of small profits but quick turnover. For small purchases, the price may not be available.
Overall, if you want to know the exact market price, you can consult the chemical raw material supplier, or check it carefully on the chemical product trading platform, in order to get the current price.