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2-Fluoro-3-Chloronitrobenzene

2-Fluoro-3-Chloronitrobenzene

Hongda Chemical

Specifications

HS Code

430125

Chemical Formula C6H3ClFNO2
Molecular Weight 177.545
Appearance Yellow to brown liquid
Boiling Point 213 - 215 °C
Melting Point 30 - 34 °C
Density 1.479 g/mL at 25 °C
Flash Point 92 °C
Solubility In Water Insoluble
Vapor Pressure Low
Odor Characteristic

As an accredited 2-Fluoro-3-Chloronitrobenzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

Packing & Storage
Packing 250g of 2 - fluoro - 3 - chloronitrobenzene packaged in a sealed glass bottle.
Storage 2 - fluoro - 3 - chloronitrobenzene should be stored in a cool, dry, well - ventilated area, away from heat sources and ignition sources. It should be stored in a tightly - sealed container to prevent leakage. Keep it separate from oxidizing agents, reducing agents, and bases to avoid potential chemical reactions. Store it at a temperature within the recommended range, typically around ambient temperature, to maintain its stability.
Shipping 2 - fluoro - 3 - chloronitrobenzene is shipped in accordance with hazardous chemical regulations. It's carefully packaged in corrosion - resistant containers, labeled clearly, and transported by carriers with proper safety measures to ensure secure delivery.
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2-Fluoro-3-Chloronitrobenzene 2-Fluoro-3-Chloronitrobenzene
General Information
Historical Development
2 - Fluoro - 3 - Chloronitrobenzene, the substance of chemistry. Its initial discovery originated from the study of various sages. At that time, the field of chemistry was gradually emerging, and researchers exhausted their wisdom to explore the mystery of matter.
It was first obtained, and everyone examined its properties, analyzed its structure, and understood its composition. As time went by, researchers made great progress in the synthesis method. At the beginning, the synthesis technique was still simple, but the yield was not abundant, and there were many impurities.
After that, the public struggled to find ways to improve, or to change the conditions of the reaction, or to use the reagent easily. After years of work, the synthesis method has been perfected, the yield has increased, and the purity is also good.
This substance has gradually become useful in the fields of industry and scientific research, contributing to the progress of many fields. Its historical evolution is one of the evidences of the development of chemistry.
Product Overview
2-Fluoro-3-chloronitrobenzene
There is currently a product named 2-fluoro-3-chloronitrobenzene. Its color may be light, and if it is crystalline, it usually depends on the situation. This is the main thing in the synthesis, and it is especially difficult in the field of production and production.
Its method usually starts with a specific aromatic compound, and it is obtained by reaction and nitrification. In turn, the components are controlled, and the degree of resistance and catalysis are all good.
Its properties are special, fluorine, chlorine, and nitro coexist in the molecule. The introduction of fluorine atoms increases its reaction activity; chlorine atoms affect its emptiness; nitro groups give its specialization. Therefore, 2-fluoro-3-chloronitrobenzene can be used for many reasons, and it is a good material for special materials and high-efficiency technologies. And it is also a good way to explore the reverse theory in the process of chemical research.
Physical & Chemical Properties
In 2024, the study of the properties of chemical substances is of great importance in the academic community. This substance is 2 - Fluoro - 3 - Chloronitrobenzene. Its physical properties, at room temperature, are colorless to light yellow liquid, clear in view, smelling has a specific odor. The density is higher than that of water, placed in water, and sinks at the bottom. The boiling point is quite high, about 200 degrees Celsius, which is caused by intermolecular forces.
In terms of its chemical properties, it is extremely active. The presence of fluorine, chlorine atoms and nitro groups causes the density of the electron cloud of the benzene ring to change. Nitro has strong electron-absorbing properties, which reduces the activity of the electrophilic substitution reaction of the benzene ring, but the density of the electron cloud in the adjacent para-position is relatively high, so the nucleophilic substitution reaction is prone to occur in the adjacent para Although fluorine and chlorine atoms are also electron-withdrawing groups, they can leave under specific conditions and lead to many reactions. Therefore, 2-Fluoro-3-Chloronitrobenzene is widely used in the field of organic synthesis and is an important intermediate for the preparation of complex compounds.
Technical Specifications & Labeling
2 - Fluoro - 3 - Chloronitrobenzene is an important chemical raw material. Its technical specifications and identification (product parameters) are extremely critical. The appearance of this product is a colorless to light yellow liquid with a special odor. Its boiling point is about [X] ° C, its melting point is [X] ° C, and its density is [X] g/cm ³. The purity must be above 99%, and the impurity content is extremely low. In terms of identification, the packaging should be clearly marked with the product name, chemical formula, hazard category and other information. When storing, it should be placed in a cool and ventilated warehouse, away from fire and heat sources. In the chemical production process, its technical specifications and identification are strictly controlled to ensure product quality and safety, and play an important role in many fields.
Preparation Method
The method of making 2 - Fluoro - 3 - Chloronitrobenzene is related to the raw materials and production process, reaction steps and catalytic mechanism.
The raw materials are selected as refined and pure products. Fluoride, chloride and nitrobenzene are all important substances. Its accurate ratio is the key to the reaction. For example, the amount of fluoride, more side reactions are produced, and less yield is low.
The production process is preferably a step-by-step reaction. First, the fluoride and nitrobenzene are reacted at a specific temperature and pressure, and the catalyst helps to promote their synthesis. Observe the reaction process, adjust the temperature and pressure in a timely manner to ensure a smooth reaction.
The reaction steps also need to be carefully observed. After the first step of the reaction, the products are finely separated and impurities are removed. Then, the chloride is introduced, the temperature and pressure are controlled again, and the second reaction is carried out. After each step of the reaction, the purity of the product is purified.
Catalytic mechanism, high-efficiency catalyst is selected. It can reduce the activation energy of the reaction and speed up the reaction process. In different reaction stages, according to the reaction characteristics, the amount and type of catalyst are adjusted to achieve the best catalytic effect, so 2-Fluoro-3-Chloronitrobenzene can be obtained with high purity and high yield.
Chemical Reactions & Modifications
Since modern times, chemical refinement, research on substances, new and new. Today there is 2 - Fluoro - 3 - Chloronitrobenzene, which is quite important in chemical synthesis. The wonderful reaction and the strange change are valued by researchers.
Looking at its chemical reaction, it often shows a specific appearance when it encounters various reagents. Or nucleophilic substitution, or electron transfer, all vary according to the surrounding conditions. The substitution position and the speed of the reaction can vary depending on the nature of the reagent, the degree of temperature, and the quality of the solvent. In order to find the best reaction path, it is necessary to carefully observe various factors and precisely regulate them.
As for its modification, it is also specialized by researchers. Or add a group, or adjust the structure to give it new energy. After modification, this substance may have different effects in materials, medicine and other fields. Or increase its stability, or strengthen its activity, in order to meet more needs and solve many difficulties. Researchers should use their concentration, use their rationality, be good at their methods, and do their best for chemical progress to open up new environments.
Synonyms & Product Names
Today there is a product called 2 - Fluoro - 3 - Chloronitrobenzene. This product is widely used in the field of chemical industry. It has different names, or because of its nature, or because of its use.
In the industry, people also call it by other names. These synonyms, although different words mean the same thing, all refer to this product. Merchants are in the market, and they are also sold under different product names, aiming to show their characteristics and attract customers' attention.
This 2 - Fluoro - 3 - Chloronitrobenzene, with its unique properties, is either used in synthesis or in the manufacture of other products. Although its synonyms and trade names are numerous and diverse, they are all familiar to chemists, and they circulate in the industry to promote the development of chemical industry.
Safety & Operational Standards
2 - Fluoro - 3 - Chloronitrobenzene Safety and Practice
2 - Fluoro - 3 - Chloronitrobenzene is a common compound in chemical research. During its experimental operation and research process, safe and standardized operation is essential.
This compound has certain chemical activity and potential danger. For storage, it should be stored in a cool, dry and well-ventilated place, away from fire, heat and oxidants. Due to its impact on the environment, it should also be stored to avoid leakage to the outside environment.
When operating, researchers must take personal protective measures. Appropriate protective clothing should be worn, including laboratory clothes, protective gloves and protective glasses, to prevent the compound from coming into contact with the skin and eyes. If you come into contact with the skin, you should immediately rinse with plenty of water and seek medical treatment according to the situation. If you come into contact with the eyes, you need to rinse with running water quickly and then seek medical attention urgently.
The experimental operation should be carried out in a fume hood to ensure that the operating environment is well ventilated to prevent the accumulation of volatile gases from compounds and endanger the health of researchers. The operation process should strictly follow the experimental operating procedures to avoid violent vibration and collision to prevent accidents.
For waste disposal, it must not be discarded at will. Waste containing 2-Fluoro-3-Chloronitrobenzene should be collected in accordance with relevant environmental protection regulations and handed over to professional institutions for proper disposal to reduce environmental pollution.
Researchers should also be familiar with relevant emergency treatment measures. In the event of a fire, appropriate fire extinguishing equipment should be selected according to its chemical properties; in the event of a leak, prompt measures should be taken to seal and clean up to prevent spread.
Only by strictly following safety and operating practices can we ensure the smooth development of the 2-Fluoro-3-Chloronitrobenzene research work, and at the same time ensure the safety of researchers and the environment.
Application Area
2-Fluoro-3-chloronitrobenzene is also a chemical material. Its application field is quite wide. In the field of pharmaceutical synthesis, it is often a key intermediate, helping doctors to make special drugs and treat various diseases. In the field of pesticide creation, it is also very useful, which can add strength to plant protection and protect the safety of crops.
Looking at its use in medicine, it can be transformed into exquisite pharmaceutical structures through various reactions to achieve the effect of healing. In pesticides, its unique structure endows pesticides with excellent properties, or increases the ability to kill insects, or strong weeding power.
This chemical product is used in the application field of medicine and pesticides, such as the help of boats, the health of mankind, and the prosperity of agriculture.
Research & Development
Nowadays, there is a chemical substance 2 - Fluoro - 3 - Chloronitrobenzene, and my research and development have been very laborious. At the beginning, the method of its synthesis was explored, and after many attempts, an effective path was found. In the optimization of reaction conditions, temperature, pressure, and catalyst dosage were carefully considered, and efforts were made to be accurate.
Then, explore its physicochemical properties, melting point, boiling point, solubility, etc., and determine in detail. Also observe its stability in different environments, and observe its reactivity with other substances.
Research results are gradually enriched, and its application is also considered. This substance may have considerable prospects in the fields of medicine, materials, etc. I will make unremitting efforts to further develop it and contribute to the field of chemistry for the world.
Toxicity Research
Taste the industry of chemical industry, new products emerge one after another, but the nature of poisons cannot be ignored. Today there is a thing called 2-Fluoro-3-Chloronitrobenzene, which has unique characteristics among chemical products.
The toxicity of this thing is really related to the safety of living beings. After various inquiries, it can be known that if it enters the body inadvertently, it may hurt the viscera, or disrupt qi and blood. Touch the skin, or cause sensitive pain; suck in the breath, or damage the lung meridian. Although the amount is different, it should not be ignored.
And observe its use, although it is a chemical material, it must be strictly followed when preparing and using it. The operator is in front of the protective equipment to keep the body intact. The disposal method must also be cautious to prevent it from escaping and contaminating the four borders.
Cover the research on toxicity, in order to ensure public safety, and also for the chemical industry to be constantly prosperous and harmless. Therefore, the poison of 2-Fluoro-3-Chloronitrobenzene must be carefully studied and prepared.
Future Prospects
Fu 2 - Fluoro - 3 - Chloronitrobenzene is also a chemical product. Its future prospects can be deeply considered. In the field of transformation, the pace is rapid, and this compound may have new developments in many aspects.
In the process of development, it may be the cornerstone of new research. With its unique chemical properties, it may help to make more special effects, cure common diseases, and benefit patients.
In the field of materials, it may also have extraordinary performance. Or it can be used to synthesize new materials with special physical properties, and it can be used in high-tech, such as electronics and aerospace, to promote progress.
Of course, 2 - Fluoro - 3 - Chloronitrobenzene has not yet realized its capabilities, but there is no way to do it, full of possibilities, like jade to be carved, it must be used in the world, and the prospect of development is limited.
Where to Buy 2-Fluoro-3-Chloronitrobenzene in China?
As a trusted 2-Fluoro-3-Chloronitrobenzene manufacturer, we deliver: Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements. Technical Excellence: Precision-engineered solutions backed by R&D expertise, from formulation to end-to-end delivery. Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.
Frequently Asked Questions

As a leading 2-Fluoro-3-Chloronitrobenzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

What are the main uses of 2-Fluoro-3-Chloronitrobenzene?
2-Fluoro-3-chloronitrobenzene is a crucial compound in the field of organic synthesis. Its main uses are quite extensive, and it has significant applications in many fields.
First in the field of pharmaceutical synthesis. Due to its unique chemical structure, it can provide a key intermediate for the synthesis of specific drugs. Through a series of fine chemical reactions, molecular structures with specific pharmacological activities can be ingeniously constructed. For example, when synthesizing some antibacterial drugs, 2-fluoro-3-chloronitrobenzene can be used as a starting material, introducing key functional groups through multi-step reactions, and then shaping drug molecules with precise antibacterial targeting, making great contributions to human resistance to disease attacks.
Furthermore, in the field of pesticide synthesis, it also plays a pivotal role. Based on it, high-efficiency and low-toxicity pesticide products can be prepared. By reasonably modifying and modifying its structure, pesticides are endowed with excellent insecticidal and weeding properties, and have little impact on the environment. It meets the needs of the current development of green agriculture, escorts the growth of crops, and ensures the stable supply of food.
In addition, in the field of materials science, 2-fluoro-3-chloronitrobenzene also has outstanding performance. It can participate in the synthesis of high-performance materials, such as some polymer materials with special optical and electrical properties. By introducing it into the polymer chain, the properties of materials can be effectively regulated to meet the strict requirements of high-end fields such as electronic devices and optical instruments, and to promote technological innovation and development in related fields.
In summary, 2-fluoro-3-chloronitrobenzene plays an indispensable role in many fields such as medicine, pesticides and materials science due to its diverse and critical uses. It is a shining treasure in the field of organic synthetic chemistry.
What are the physical properties of 2-Fluoro-3-Chloronitrobenzene?
2-Fluoro-3-chloronitrobenzene is one of the organic compounds. It has unique physical properties, which are related to chemical industry, medicine and other fields, and is quite important.
First of all, under room temperature, 2-fluoro-3-chloronitrobenzene is a light yellow to light brown liquid, which is clear in appearance. The characterization of its color can help to identify this substance. And it has a special smell. Although this smell is not extremely strong, it is also one of its characteristics.
When it comes to density, this substance is more dense than water. If placed in water, it will sink to the bottom of the water. This property is of great significance in chemical operations such as separation and purification, and can provide a basis for the design and implementation of related processes.
Furthermore, the boiling point is also an important physical property. Its boiling point is within a certain range, and this value determines its state change under heating and other conditions. In a suitable temperature environment, it can be converted from liquid to gaseous state. This phase change characteristic is a key consideration in separation processes such as distillation and rectification. It can help chemical practitioners effectively separate mixtures and obtain high-purity target products.
In terms of solubility, 2-fluoro-3-chloronitrobenzene has a certain solubility in organic solvents such as ethanol and ether, but it has little solubility in water. This property makes it possible to select a suitable solvent according to its solubility during chemical synthesis and reaction medium selection to promote the reaction, improve the reaction efficiency and product purity.
In addition, the melting point is also a physical property that cannot be ignored. Although it is liquid at room temperature, when the temperature is reduced to a specific value, that is, the melting point, it will solidify into a solid state. This melting point value is crucial for the setting of its storage and transportation conditions. It is necessary to ensure that the ambient temperature is higher than the melting point to prevent it from solidifying and affecting subsequent use.
In summary, the physical properties of 2-fluoro-3-chloronitrobenzene, such as properties, density, boiling point, solubility, melting point, etc., are interrelated and have important guiding significance in chemical production, scientific research experiments, etc., laying the foundation for in-depth understanding and rational use of this substance.
What is the chemistry of 2-Fluoro-3-Chloronitrobenzene?
2-Fluoro-3-chloronitrobenzene is also an organic compound. Its molecular structure contains groups such as fluorine, chlorine and nitro, which endow it with unique chemical properties.
In terms of reactivity, the nitro group is a strong electron-absorbing group, which reduces the electron cloud density of the benzene ring and its electrophilic substitution reactivity. However, the electron cloud density of the adjacent and para-sites is relatively high, so nucleophiles are prone to attack these two positions. Although fluorine and chlorine are halogen atoms, they have a certain electron-absorbing induction effect, but they also have electron-giving conjugation effect. However, in general, they reduce the electron cloud density of the benzene ring and also affect the reactivity.
In the hydrolysis reaction, under appropriate conditions, the halogen atom can be replaced by the hydroxyl group. Because the fluorine atom is firmly bound to the benzene ring, hydrolysis is relatively difficult; while the chlorine atom is more easily hydrolyzed, the corresponding phenolic derivatives can be obtained.
In the nucleophilic substitution reaction, the benzene ring is more susceptible to attack by nucleophilic reagents due to the electron-withdrawing action of the nitro group. The nucleophilic reagent can attack the carbon atom connected to the halogen atom, and the halogen atom leaves to form a new compound.
During the reduction reaction, the nitro group can be reduced to nitrogen compounds with different valence states such as amino groups. For example, iron and hydrochloric acid are used as reducing agents, and the nitro group can be gradually reduced to
The substitution activity of halogen atoms, chlorine is more active than fluorine, and chlorine atoms are more easily replaced in nucleophilic substitution and other reactions. Due to the high carbon-fluorine bond energy, it is more difficult to break; while the carbon-chlorine bond energy is relatively small, and it is more easy to break the bond.
The chemical properties of 2-fluoro-3-chloronitrobenzene are affected by the interaction of the groups they contain. In the field of organic synthesis and other fields, various transformations can be achieved due to these characteristics, resulting in the preparation of various useful organic compounds.
What is 2-Fluoro-3-Chloronitrobenzene production method?
The preparation of 2-fluoro-3-chloronitrobenzene is an important issue in chemical technology. In the past, specific reaction paths were commonly used to prepare this compound.
One method is to use a specific aromatic compound as the starting material. First, the aromatic compound interacts with the fluorine-containing reagent under appropriate reaction conditions. This reaction requires precise control of many factors such as reaction temperature, pressure and reaction time. The fluorine-containing reagent used must be carefully selected according to the characteristics of the raw material and the reaction requirements, so that the fluorine atom can be effectively introduced into the specific position.
After the fluorine atom is successfully introduced, the product is reacted with the chlorine-containing reagent. This step also requires fine regulation of the reaction environment, such as the choice of solvent and the addition of catalyst. A suitable solvent can promote the reaction, and a suitable catalyst can significantly improve the reaction rate and selectivity, so that the chlorine atom can be precisely connected to the desired position, so as to obtain the precursor of 2-fluoro-3-chloronitrobenzene.
Then, the precursor is subjected to nitrification. During the nitrification process, the ratio of reagents such as nitric acid and sulfuric acid, and the temperature of the reaction have a profound impact on the reaction result. If the temperature is too high, or the side reaction increases, the purity of the product decreases; if the temperature is too low, the reaction rate is delayed and takes a long time.
Throughout the preparation process, each step of the reaction needs to be closely monitored and fine-tuned. From the selection of raw materials, the ratio of reagents, and even the material and performance of the reaction equipment, the quality and yield of the final product are all related. Only by carefully controlling each link can high-purity 2-fluoro-3-chloronitrobenzene be prepared efficiently and stably.
What are the precautions in storage and transportation of 2-Fluoro-3-Chloronitrobenzene?
2-Fluoro-3-chloronitrobenzene is also an organic compound. During storage and transportation, many matters need to be carefully noted.
First of all, storage, this compound is more active, and should be placed in a cool and well-ventilated place. Because of its fear of heat, high temperature can easily cause chemical reactions, or cause danger, so the warehouse temperature should be controlled in a suitable range, not too high. And because of its sensitivity to light, strong light exposure may also affect its stability, so it should be stored in a dark place, can be used in dark containers, or stored in places where light is difficult to reach.
Furthermore, it needs to be separated from oxidizing agents, reducing agents, alkalis and other substances. Due to its chemical properties, if it is mixed with the above substances, it is prone to violent reactions, such as oxidation-reduction reactions, which can lead to serious consequences such as fire and explosion. The storage area should also be equipped with corresponding fire-fighting equipment and leakage emergency treatment equipment for emergencies.
As for transportation, make sure that the packaging is intact before transportation. Packaging materials must be able to effectively resist vibration, collision and friction to prevent leakage of items due to damaged packaging. During transportation, vehicles should run smoothly, avoid violent actions such as sudden braking and sharp turns, and reduce the impact of vibration on the goods.
At the same time, transportation personnel need to be familiar with the characteristics of the compound and emergency treatment methods. If there is an unexpected situation such as leakage on the way, they can take countermeasures quickly and correctly. It is strictly forbidden to transport with contraindicated items in the same vehicle to prevent danger caused by interaction during transportation. And the transportation vehicle should hang the corresponding dangerous chemical label to warn others to pay attention. In this way, the safety of 2-fluoro-3-chloronitrobenzene in storage and transportation must be ensured.