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2-Fluoro-1-Iodo-4-Nitrobenzene

2-Fluoro-1-Iodo-4-Nitrobenzene

Hongda Chemical

Specifications

HS Code

774268

Chemical Formula C6H3FINO2
Molecular Weight 267.00
Appearance Solid
Color Off - white to light yellow
Melting Point 56 - 58 °C
Solubility In Water Insoluble
Solubility In Organic Solvents Soluble in common organic solvents like dichloromethane, chloroform
Purity Typically high - purity, e.g., 97%+

As an accredited 2-Fluoro-1-Iodo-4-Nitrobenzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

Packing & Storage
Packing 100g of 2 - fluoro - 1 - iodo - 4 - nitrobenzene packaged in a sealed glass bottle.
Storage 2 - fluoro - 1 - iodo - 4 - nitrobenzene should be stored in a cool, dry, well - ventilated area. Keep it away from heat sources, flames, and oxidizing agents. Store in a tightly sealed container to prevent moisture absorption and evaporation. Label the storage container clearly to avoid confusion. It's best stored separately from incompatible substances to prevent potential reactions.
Shipping 2 - fluoro - 1 - iodo - 4 - nitrobenzene is shipped in sealed, corrosion - resistant containers. It adheres to strict hazardous chemical shipping regulations, ensuring proper handling, storage, and transportation to prevent spills and risks.
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2-Fluoro-1-Iodo-4-Nitrobenzene 2-Fluoro-1-Iodo-4-Nitrobenzene
General Information
Historical Development
Fu 2 - Fluoro - 1 - Iodo - 4 - Nitrobenzene is also an organic compound. At the beginning of its inception, it was the result of chemists' painstaking research and repeated trials. At that time, chemical skills were not as exquisite as they are today, and the road to exploration was full of thorns.
With perseverance, chemists analyzed the characteristics of various elements and deduced the reaction mechanism. After countless blending of raw materials and changing conditions, they achieved something. At the beginning, the yield was low and the quality was uneven.
However, the predecessors were not discouraged and continued to improve the process. Or optimize the reaction vessel, or search for a better catalyst. Years pass, technology progresses. From ignorance and temptation to precise control, the preparation of 2-Fluoro-1-Iodo-4-Nitrobenzene is becoming more and more mature, and its application is also becoming more and more extensive. It has emerged in the fields of medicine and materials, laying the foundation for the development of later chemistry. It is a shining pearl in the history of chemistry.
Product Overview
2 - Fluoro - 1 - Iodo - 4 - Nitrobenzene is also a chemical substance. Its color may be light, and it is solid. It has special properties. Its molecular framework, fluorine, iodine, and nitrobenzene are cleverly intertwined, and each atom is intertwined with other atoms. This is a special property.
This substance is of interest in the field of chemical research. In the synthesis, it can be used as an important raw material, and it can be used as a kind of reaction to other useful compounds. The fluorine atom has special activity, and the iodine atom also has anti-reactive activity. The nitro group can affect the entire sub-cloud, causing it to be anti-reactive, such as nuclear substitution, even, etc., all of which can play a role. The synthesis provides many possibilities, and the promotion of chemical research is a step. It has its own value that cannot be ignored in multiple fields such as materials science and material research.
Physical & Chemical Properties
2 - Fluoro - 1 - Iodo - 4 - Nitrobenzene is an organic compound with unique physicochemical properties. Its appearance may be crystalline and its color is nearly yellowish, due to the halogen and nitro groups in the molecular structure.
In terms of physical properties, the melting point is in a specific range, or it is melted in a specific temperature range due to intermolecular forces and structures. The boiling point is also characteristic. It boils at a certain temperature due to the interaction between molecular mass and molecules. In terms of solubility, it may have a certain solubility in organic solvents such as ethanol and ether, because it has a certain hydrophobicity and is compatible with the structure of organic groups.
From the chemical properties, its halogen atoms are active and can undergo nucleophilic substitution reactions. The nitro group strongly absorbs electrons, which decreases the electron cloud density of the benzene ring and changes the activity of the electrophilic substitution reaction of the benzene ring. And this compound may have a certain degree of oxidation, because the nitro group can participate in the redox process.
The above properties have a great impact on its application in the field of organic synthesis and provide a variety of paths for the synthesis of complex organic molecules.
Technical Specifications & Labeling
There is a product today, named 2 - Fluoro - 1 - Iodo - 4 - Nitrobenzene. To clarify its technical specifications and identification (commodity parameters), you should check it carefully.
The technical specifications of this product are related to its chemical composition and characteristics. Its chemical structure is established, and it contains fluorine, iodine, nitro and other groups, which determine its chemical properties. The synthesis method requires precise steps, temperature control, timing control, and selection of suitable reagents to achieve high purity.
Identification (commodity parameters) is also heavy, when it is clear that its purity geometry and impurity geometry. Appearance, color, and state should be detailed. And it is necessary to note its dangerous characteristics, such as reaction in case of heat and fire, in order to properly store and transport.
Only by relying on this technical specification and identification (commodity parameters) can this product be used properly in the chemical industry, safely and without worry.
Preparation Method
To prepare 2 - Fluoro - 1 - Iodo - 4 - Nitrobenzene, the method is as follows: Take the raw material and select the pure one. Based on benzene, first make benzene and fluoride meet, according to the appropriate temperature and pressure, and perform a substitution reaction to obtain fluorobenzene. Then, make fluorobenzene and iodide combine, supplemented by a catalyst to control the degree of reaction to make 1 - Iodo - 2 - Fluorobenzene. After that, add a nitrifying agent, and at a moderate temperature, make the nitro group into the benzene ring to obtain 2 - Fluoro - 1 - Iodo - 4 - Nitrobenzene. After each step of the reaction, it needs to be purified to remove impurities. The reaction device is corrosion-resistant, and the temperature control and pressure control devices are also complete to ensure a stable reaction, increase the yield, and obtain excellent products.
Chemical Reactions & Modifications
In recent years, 2 - Fluoro - 1 - Iodo - 4 - Nitrobenzene has been studied in terms of the reaction and modification of chemical reactions.
It should also be used in the past, and there are many limitations. Or the reaction is difficult, time-consuming and the yield is not good; or the use of various agents is expensive and difficult to be widely used. Today's researchers are exhausted and eager for a good method.
Have tried it with a new catalyst, and it has worked wonders. The reaction speed increases, the yield also increases, and the side effects are less. Looking at its modification, in the past, this material property was insufficient, and in some situations, it was difficult to make the best use of it. Now through ingenious thinking, its structure, stability, and activity can be adjusted, and it can be developed in a wider range.
Although the research path is difficult, many people will persevere. The reaction and modification of 2-Fluoro-1-Iodo-4-Nitrobenzene will be more refined in the future, so as to benefit all industries.
Synonyms & Product Names
2-Fluoro-1-Iodo-4-Nitrobenzene, the synonyms and trade names of this substance are quite crucial. In the field of chemical research, knowing its many terms is helpful for accurate communication and research.
Its synonyms are formed by the academic community through long-term research and cognition. Based on structural characteristics or derived from reaction characteristics, many scholars refer to this compound in different expressions. The trade name is mostly determined by the manufacturer according to marketing activities and product positioning.
In the chemical research analogy recorded in ancient books, although it is difficult to find a direct correspondence, the exploration ideas are similar. In the past, chemists, in order to clarify the characteristics of substances, also studied the references of various names to confirm that they are the same thing. Today, we study the synonyms and trade names of 2-Fluoro-1-Iodo-4-Nitrobenzene, and hope to fully understand this thing, which will pave the way for subsequent research and application, so that both academia and industry can use it accurately and without confusion.
Safety & Operational Standards
2 - Fluoro - 1 - Iodo - 4 - Nitrobenzene Safety and Practice
2 - Fluoro - 1 - Iodo - 4 - Nitrobenzene is an important chemical that is often used in our research work. However, this product has certain potential hazards, so it is essential to know its safety and practice practices.
#1. Safety Hazards
2 - Fluoro - 1 - Iodo - 4 - Nitrobenzene is toxic. If it is accidentally exposed to the skin, inhaled or ingested, it may cause serious harm to the human body. It may irritate the skin and eyes, causing redness, swelling and pain. And inhaling the dust or vapor of the substance, or causing damage to the respiratory system, or even life-threatening.
#2. Operating Specifications
1. ** Operating Environment **: The operation must be carried out in a well-ventilated place, preferably in a laboratory with a fume hood. This can effectively reduce the concentration of the substance in the air and reduce the risk of inhalation.
2. ** Personal Protection **: The operator should be fully armed and wear appropriate protective clothing, gloves and goggles. The protective clothing should be able to resist the penetration of the substance, and the gloves should be made of suitable materials to ensure that there is no leakage. The goggles can fully protect the eyes and avoid splash damage.
3. ** Access Operation **: When taking 2 - Fluoro - 1 - Iodo - 4 - Nitrobenzene, be sure to move gently to avoid violent vibrations or dumping to prevent leakage. Use appropriate utensils, such as spoons or pipettes, to accurately measure the required amount, and must not be in direct contact with hands.
4. ** Emergency Treatment **: In the unfortunate event of a leak, immediate action should be taken. Quickly evacuate unrelated personnel and turn on ventilation equipment at the same time. Cover and collect leaks with appropriate materials, such as sand, etc., place them properly in specific containers, and dispose of them according to regulations. If a person comes into contact with this substance, skin contacts should be rinsed with plenty of water immediately, and eye contacts should be carefully rinsed and seek medical attention; if inhaled or ingested, be sure to seek medical attention immediately.
Our chemical researchers should strictly abide by this safety and operating practice to ensure their own safety and ensure the smooth conduct of research.
Application Area
Today, there is a compound named 2 - Fluoro - 1 - Iodo - 4 - Nitrobenzene. This compound is used in many fields. In the field of medicinal chemistry, it can be used as a key intermediate to help create new drugs to deal with difficult diseases, or as a sharp edge to fight diseases. In materials science, it can participate in the synthesis of special materials, so that the materials have unique optoelectronic properties and are used in high-end electronic devices, such as advanced display screens, sensitive sensors, etc. In the field of organic synthetic chemistry, it is an important building block, which can build complex organic molecular structures, expand the boundaries of organic synthesis, enable chemists to explore novel molecular structures, generate more functional and specific organic materials and products, and contribute to the development of many industries.
Research & Development
The rise of modern chemistry is a great contribution to the investigation of matter. Today there is a thing named 2 - Fluoro - 1 - Iodo - 4 - Nitrobenzene. Our generation of chemical researchers have explored and studied it in order to find a way to develop.
This thing has unique properties and delicate structures. It may have extraordinary potential in the fields of organic synthesis. We have extensively checked the classics, studied the principles in depth, and through various experiments, observed its reaction state and analyzed its change rules.
In the experiment, temperature control, pressure regulation, and agent selection all need to be fine. Observe its response to various things, or generate new substances, or show abnormal states. After months of work, a little gain. However, if we want to make it widely used and promote its development, we still need to study it unremitting. With the efforts of our generation, we will make this product shine in the chemical, pharmaceutical and other industries, and be used by the world to promote the progress of chemistry and create a blessing for all people.
Toxicity Research
The chemical industry is related to people's livelihood, but the study of poisons in the process should not be careless. Today there is 2 - Fluoro - 1 - Iodo - 4 - Nitrobenzene, and our generation should investigate its toxicity in detail.
The properties of this substance are based on chemical principles, or contain halogen fluorine, iodine, and nitro groups. Its structure is strange and may be toxic. Fluoride is very active, and it enters the body or disrupts the biochemical order. Although iodine is beneficial, its effect is unknown in this complex state. Nitro is also toxic and can disturb cells.
In order to clarify its harm, we should set up various experiments by scientific methods. Taking the animal as a model, observe the physiological changes and damage to the organs after ingestion. Also observe its volatilization in the gas and the state of the person who touches it. After careful study and detailed data recording, we can know the depth of its toxicity, which is the evidence for protection and disposal, so that the harm of this thing can be reduced to invisible, ensuring everyone's well-being and protecting the environment.
Future Prospects
The future development concerns 2 - Fluoro - 1 - Iodo - 4 - Nitrobenzene. Although it is only a research object at present, it contains countless possibilities.
I look at this chemical substance, its unique structure and strange properties, or in the field of medicine, it can be a good medicine to cure diseases and cure difficult diseases; or in the field of materials, it can be turned into new materials to improve the performance of devices, strong and durable.
Although the road ahead is unknown, we scientific researchers should move forward with the heart of exploration and determination. With time and careful study, 2 - Fluoro - 1 - Iodo - 4 - Nitrobenzene will be able to shine, benefit the world, open a new chapter in the future, and achieve extraordinary things.
Where to Buy 2-Fluoro-1-Iodo-4-Nitrobenzene in China?
As a trusted 2-Fluoro-1-Iodo-4-Nitrobenzene manufacturer, we deliver: Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements. Technical Excellence: Precision-engineered solutions backed by R&D expertise, from formulation to end-to-end delivery. Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.
Frequently Asked Questions

As a leading 2-Fluoro-1-Iodo-4-Nitrobenzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

What are the main uses of 2-Fluoro-1-Iodo-4-Nitrobenzene?
2-Fluoro-1-iodine-4-nitrobenzene is also an organic compound. Its main use involves the field of organic synthesis.
In the synthesis of medicine, this compound is often a key intermediate. Because of its unique structure, it contains fluorine, iodine and nitro functional groups, which can be introduced into drug molecules through chemical reactions to change the physical, chemical and biological activities of drugs. For example, it can increase the lipophilicity of drugs, promote them to cross biofilms, and improve bioavailability; or because of the characteristics of fluorine and iodine atoms, it affects the interaction between drugs and targets and optimizes pharmacological activity.
In the field of materials science, 2-fluoro-1-iodine-4-nitrobenzene can also be used. It can be incorporated into the polymer material structure by polymerization and other means to endow the material with specific electrical, optical or thermal properties. If conjugated polymers with specific photoelectric properties are prepared for use in organic optoelectronic devices, such as organic Light Emitting Diode (OLED), organic solar cells, etc., it is expected to improve the efficiency and stability of the device.
It is also an important raw material in the creation of pesticides. By chemical modification, pesticide compounds with high insecticidal, bactericidal or herbicidal activities can be synthesized. The functional groups contained in it can participate in the action of targets in pests, pathogens or weeds, achieve the effect of control, and may have the advantages of environmental friendliness and low toxicity due to structural characteristics, which meets the needs of the development of modern pesticides.
In short, 2-fluoro-1-iodine-4-nitrobenzene, with its unique structure, plays an important role in the organic synthesis of medicine, materials, pesticides and other fields, providing a key foundation for the creation of new compounds and materials.
What are the physical properties of 2-Fluoro-1-Iodo-4-Nitrobenzene?
2-Fluoro-1-iodine-4-nitrobenzene is one of the organic compounds. Its physical properties are quite specific, so let me explain it to you in detail.
In terms of its appearance, under normal temperature and pressure, 2-fluoro-1-iodine-4-nitrobenzene often appears in a solid state, mostly light yellow. This color is light and discernible, like the mist at the beginning of the morning, faintly glowing.
As for the melting point, it is about a specific temperature range. This melting point is the critical temperature at which a substance changes from a solid state to a liquid state. The melting point of 2-fluoro-1-iodine-4-nitrobenzene is just like the key node of its physical properties, so that it can maintain the shape of a solid state under a specific environment. When the temperature gradually rises near the melting point, the thermal motion of the molecule intensifies, the solid structure gradually loosens, and then melts into a liquid.
The boiling point is also one of its important physical properties. The boiling point is the temperature at which a substance changes from a liquid state to a gaseous state. The boiling point of 2-fluoro-1-iodine-4-nitrobenzene has a certain value in an atmospheric pressure environment. At this boiling point, a large number of bubbles inside the liquid are formed and escape, and the material state changes from liquid to gas. However, the boiling point is greatly affected by external pressure. If the pressure changes, the boiling point also changes.
Its density cannot be ignored. The density is also the mass of the substance per unit volume. The density of 2-fluoro-1-iodine-4-nitrobenzene determines its floating and sinking state in the liquid system. Due to its specific molecular structure and orderly atomic combination, the density has a certain value, which may be different from that of common solvents. This characteristic has a significant impact in experimental operations such as separation and mixing.
In terms of solubility, 2-fluoro-1-iodine-4-nitrobenzene has a certain solubility in organic solvents such as dichloromethane and chloroform. Due to the principle of "similar miscibility", its organic structure is compatible with the intermolecular forces of organic solvents, so it can be dissolved in it. In water, the solubility is very small, and it is difficult to form an effective interaction with water due to the large difference in molecular polarity between water molecules.
The color, melting point, boiling point, density and solubility of 2-fluoro-1-iodine-4-nitrobenzene are of great significance in the fields of organic synthesis and drug research and development. They are also key considerations for chemical production.
What is the chemistry of 2-Fluoro-1-Iodo-4-Nitrobenzene?
2-Fluorine-1-iodine-4-nitrobenzene has unique chemical properties and is worth studying. In this compound, the fluorine atom has electronegativity, which can cause the density distribution of the electron cloud of the benzene ring to change, which affects its reactivity. The presence of fluorine often reduces the density of the electron cloud in the adjacent and para-position slightly. In the electrophilic substitution reaction, its localization effect is different from that of other atoms.
Although the iodine atom is large, it has strong polarizability. In some reactions, iodine is easy to leave, providing an opportunity for the nucleophilic substitution reaction. And the steric resistance of the iodine atom cannot be ignored, which affects the overall conformation and reaction path of the molecule.
Furthermore, the nitro group is a strong electron-absorbing group, which strongly reduces the electron cloud density of the benzene ring, making the benzene ring more stable, but also making it more difficult for the electrophilic substitution reaction to occur. In the nucleophilic substitution reaction, the nitro group can stabilize the reaction intermediate by means of the conjugation effect, thereby promoting the reaction.
2-fluoro-1-iodine-4-nitrobenzene encounters the nucleophilic reagent, and the iodine atom is often the target of nucleophilic attack, resulting in nucleophilic substitution. If the activity of the nucleophilic reagent is high, the reaction is more likely to occur. In the case of electrophilic reagents, due to the joint action of nitro and fluorine, the reaction check point may be
In redox reactions, nitro groups can be reduced, while fluorine and iodine are relatively stable and do not easily participate in such reactions, unless certain conditions are met. Its physical properties are also affected by these groups, such as melting point, boiling point, etc., which vary due to changes in intermolecular forces. This compound is often used as a key intermediate in the field of organic synthesis, and its group properties can be used to construct complex organic molecular structures.
What are 2-Fluoro-1-Iodo-4-Nitrobenzene synthesis methods?
The synthesis of 2-fluoro-1-iodine-4-nitrobenzene is often carried out by various organic chemical methods. First, nitrobenzene compounds can be started. First, nitrobenzene is halogenated to introduce fluorine atoms. This halogenation reaction requires the selection of suitable halogenating reagents, such as fluorine-containing reagents. Under appropriate reaction conditions, such as specific temperatures, solvents and catalysts, the specific position of the benzene ring of nitrobenzene is fluorinated to obtain fluorine-containing nitrobenzene derivatives.
Then, the obtained fluorine-containing nitrobenzene is iodized. The iodization step also requires careful selection of iodizing reagents, and control of the reaction conditions, so that iodine atoms are precisely introduced into the target position of the benzene ring, forming the required spatial layout with fluorine atoms and nitro groups, and finally obtaining 2-fluoro-1-iodine-4-nitrobenzene.
In addition, there are also those who use the benzene ring as the starting material. First, nitro, fluorine atoms and iodine atoms are introduced into the benzene ring in sequence. Nitro groups are introduced, often in a mixed acid system of nitric acid and sulfuric acid, to nitrate benzene, and nitro groups are introduced into the benzene ring. Subsequently, through fluorination reactions, fluorine atoms are introduced under appropriate conditions with suitable fluorine-containing reagents according to the above Finally, the target product 2-fluoro-1-iodine-4-nitrobenzene is obtained by iodization reaction. During each step of the reaction, the separation and purification of the intermediate need to be properly handled to ensure the smooth progress of the reaction and the purity of the product. Precise control of various reaction conditions, such as temperature, reactant ratio, reaction time, etc., are the keys to synthesizing this compound.
2-Fluoro-1-Iodo-4-Nitrobenzene What are the precautions in storage and transportation?
2-Fluoro-1-iodine-4-nitrobenzene is also an organic compound. During storage and transportation, many matters need to be paid attention to.
First storage, this compound should be placed in a cool, dry and well-ventilated place. Because of its certain chemical activity, heat or moisture can easily cause changes, resulting in damage to its quality. If the temperature is too high, or the reaction is accelerated, it is even dangerous for safety; if the humidity is too high, it may interact with water vapor and cause the composition to change. Therefore, it is essential to choose a suitable storage environment.
Furthermore, it should be stored separately from oxidants, reducing agents and alkalis. The chemical properties of 2-fluoro-1-iodine-4-nitrobenzene make it prone to chemical reactions or dangerous conditions such as fire and explosion when it comes into contact with such substances. Be sure to store it strictly in sections to avoid contact with each other.
Storage containers should also not be ignored. A well-sealed container must be used to prevent volatilization and leakage. Leakage not only causes material loss, but also escapes substances or endangers the environment and personal health. It is also very important to choose a container with suitable materials, such as certain materials or reactions with compounds, which affect its stability.
As for transportation, make sure the packaging is firm. During transportation, vibration and collision are inevitable. If the packaging is not solid, it is easy to cause damage to the container and material leakage. Special packaging materials and methods are selected to ensure safe transportation.
When transporting, relevant regulations and standards must also be followed. This compound may be a dangerous chemical, and the transportation qualifications, labels and documents must be in compliance. Transport personnel should also be professionally trained and familiar with emergency handling methods. In case of leakage, they can be disposed of quickly and properly to minimize harm. In short, when storing and transporting 2-fluoro-1-iodine-4-nitrobenzene, many details are related to safety and quality, and must be handled with caution.