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2-Fluoro-1-Iodo-4-Methylbenzene

2-Fluoro-1-Iodo-4-Methylbenzene

Hongda Chemical

Specifications

HS Code

307060

Chemical Formula C7H6FI
Molecular Weight 222.024 g/mol
Appearance Liquid (usually)
Boiling Point Around 190 - 192 °C
Density Data may vary, typically in the range of halogenated aromatic compounds
Solubility In Water Insoluble
Solubility In Organic Solvents Soluble in common organic solvents like ethanol, ether, etc.
Vapor Pressure Low at room temperature

As an accredited 2-Fluoro-1-Iodo-4-Methylbenzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

Packing & Storage
Packing 100g of 2 - fluoro - 1 - iodo - 4 - methylbenzene in a sealed, chemical - resistant bottle.
Storage 2 - fluoro - 1 - iodo - 4 - methylbenzene should be stored in a cool, dry, well - ventilated area away from sources of ignition and heat. Keep it in a tightly sealed container, preferably made of corrosion - resistant materials like glass or certain plastics. Store it separately from oxidizing agents and reactive substances to prevent unwanted chemical reactions.
Shipping 2 - fluoro - 1 - iodo - 4 - methylbenzene is shipped in well - sealed, corrosion - resistant containers. It adheres to strict hazardous chemical shipping regulations, ensuring proper handling and transport to prevent leakage and environmental or safety risks.
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2-Fluoro-1-Iodo-4-Methylbenzene 2-Fluoro-1-Iodo-4-Methylbenzene
General Information
Historical Development
The chemical industry is changing with each passing day, and new things are emerging one after another. Today there is 2 - Fluoro - 1 - Iodo - 4 - Methylbenzene, which is gradually emerging in the field of organic synthesis.
Looking back in the past, the road of chemical research has been difficult and long. At the beginning, Zhu Xian explored the properties of matter and analyzed its structure, so he had clues about this thing. In the early days, limited by skills and cognition, it was difficult to obtain this compound. However, scientific researchers, perseverance, through the spring and autumn, through countless trials and errors, in the reaction conditions, raw material ratio and other aspects, repeated research.
Years pass, science and technology advance day by day. New instruments and methods have emerged, and the method of synthesizing this product has gradually been perfected. From the initial complexity, it can be prepared more stably today, during which the blood of countless chemists has been condensed. Today, 2-Fluoro-1-Iodo-4-Methylbenzene has become an indispensable raw material in many fields, and its historical evolution is a vivid portrayal of the development of chemistry.
Product Overview
2 - Fluoro - 1 - Iodo - 4 - Methylbenzene is an organic compound. In this compound, fluorine (Fluoro), iodine (Iodo) and methyl (Methyl) are respectively connected to specific positions in the benzene ring. It has unique chemical properties. Due to the electronegativity of fluorine atoms, it can affect the electron cloud distribution of molecules, change the electron cloud density of the benzene ring, and then affect its reactivity. Although iodine atoms are large in size, they can be used as leaving groups in some reactions to participate in nucleophilic substitution and other reactions. Methyl has an electron supply effect on the benzene ring, which affects the stability and reaction tendency of compounds to a certain extent. The compound may have applications in the field of organic synthesis. It can be used as an intermediate to build more complex organic molecular structures through various chemical reactions. It may play an important role in the fields of medicinal chemistry and materials science, and help to develop new drugs or functional materials.
Physical & Chemical Properties
2024 is the year of Jiachen, and Taisui on duty is General Li Cheng. If you commit Taisui in 2024, you can ask the Taisui symbol to resolve it. Those who commit Taisui have many problems in career, emotion, health, etc. The following briefly describes the physical and chemical properties of 2 - Fluoro - 1 - Iodo - 4 - Methylbenzene.
This substance has a colorless to slightly yellow color and is like a liquid. Looking at its physical properties, it has a special odor, moderate density, and can maintain a liquid state in a certain temperature range. The boiling point and melting point are specific, which is related to its physical state changes.
Discusses chemical properties, its fluorine, iodine and methyl, and its reactivity is unique. The structure of the benzene ring allows it to participate in reactions such as electrophilic substitution. Fluorine atoms are electronegative, which affects molecular polarity; iodine atoms are active and can initiate specific chemical transformations; methyl groups affect their steric resistance and electron cloud distribution. This substance is used in the chemical industry or as an intermediate in organic synthesis to prepare fine chemicals. Its physicochemical properties are the cornerstone of its application.
Technical Specifications & Labeling
Today there is a product called 2 - Fluoro - 1 - Iodo - 4 - Methylbenzene. The preparation technology involves many factors. The purity of the first raw material, choose the best fluoride, iodide and methyl benzene, so that the impurities are almost non-existent.
When operating, according to the precise measurement, control the temperature and time, so that the reaction follows the rules. If the temperature is too high, the product will change easily, and if it is too low, the reaction will be slow. The reaction time also needs to be appropriate. If it is not enough, the raw material will be difficult to melt, and if it is too long or the side branches will change.
As for the identification of the product, its characteristics are recorded in detail, and its color, taste and state are all required. Measure its melting point and boiling point to determine its purity. Looking at its spectrum, the genera of infrared and nuclear magnetism can be used as evidence. This is the principle and standard of technology, so that this product can be used and is correct for people.
Preparation Method
Now I want to make 2 - Fluoro - 1 - Iodo - 4 - Methylbenzene. The method of making this product is related to the raw materials and production process, reaction steps and catalytic mechanism. The selection of raw materials should be selected to make the reaction smooth. The production process must be carefully studied and considered, and each step should be carried out in an orderly manner.
The reaction step is to determine the initial reaction and control its conditions, such as temperature and pressure, so that the reaction occurs as expected. Then, observe the formation of intermediate products and adjust them in time to make the target product. As for the catalytic mechanism, choose the appropriate catalyst to promote the reaction rate, reduce the activation energy, and increase the yield of the product.
Thus, 2 - Fluoro - 1 - Iodo - 4 - Methylbenzene has been prepared in a prudent manner and in accordance with scientific rules, with the expectation of satisfactory results.
Chemical Reactions & Modifications
In the chemical industry, if you want new products, you must study the way of reaction and modification. Today there is 2 - Fluoro - 1 - Iodo - 4 - Methylbenzene, which is very important in chemical research.
The reaction of its preparation requires careful study of the ratio of various reactants, the influence of temperature and catalyst. For example, halogenation reactions, the introduction position and quantity of halogen atoms are related to the purity and yield of the product. Or the reaction solvent can be changed to increase the solubility and reactivity of the reactants; the reaction time can be adjusted to find the best node, so that the reaction is sufficient but not excessive.
As for modification, different functional groups can be introduced to change their physical and chemical properties. Or add nitrogen-containing groups to give them special electronic effects and spatial structures, or graft long-chain alkyl groups to change their solubility and surface activity. Through the investigation of this reaction and modification, products with better properties can be obtained to meet the needs of chemical industry and to develop their functions in materials, medicine and other fields.
Synonyms & Product Names
Today there is a thing named 2 - Fluoro - 1 - Iodo - 4 - Methylbenzene. This thing has attracted much attention in the field of chemistry. Its synonymous name can also be investigated.
The book of chemistry of the watcher, or there are people who call it by other names. The synonymous names among them are either based on their structural characteristics or their properties. As for the names of commodities, merchants may be easy to remember or unique, and there are also different names.
Although the names are special, they all refer to the same thing. It is used in chemical experiments and industrial production. Chemists explore its properties for better applications; merchants manage this thing in the hope that it will profit from the market. Although the name of the synonym and the name of the commodity are different names, they are actually related to the research and distribution of this thing, and cannot be ignored.
Safety & Operational Standards
2 - Fluoro - 1 - Iodo - 4 - Methylbenzene Safety Production and Operation Specifications
Fu 2 - Fluoro - 1 - Iodo - 4 - Methylbenzene, chemical products are also used. To ensure its safe production and standardized operation, the first priority is the right environment. Place it in a dry and well-ventilated place, away from fire and heat sources to prevent accidental explosion.
During operation, make sure that the operator wears suitable protective equipment. Dress in chemical-proof clothing, wear anti-corrosion gloves on hands, and eye goggles for comprehensive protection to avoid damage. When taking it, the action should be slow and stable to avoid spilling and volatilization. If it is accidentally spilled, cover it with inert materials such as sand and vermiculite, collect it carefully, dispose of it according to regulations, and do not discard it at will.
Furthermore, storage is also important. Sealed and stored in a cool, low temperature place, away from oxidants, strong alkalis and other substances, because it may react violently, causing danger. Check its storage status regularly to prevent leakage.
During transportation, according to its dangerous characteristics, choose suitable transportation methods and tools. Make sure the container is stable and prevent it from being damaged due to bumps and collisions. And carry emergency treatment equipment and materials with the car, just in case.
In short, the safe production and operation of 2 - Fluoro - 1 - Iodo - 4 - Methylbenzene is related to the safety of the operator and the peace of the environment.
Application Area
2 - Fluoro - 1 - Iodo - 4 - Methylbenzene is also an organic compound. Its application field is quite wide. In the field of medicinal chemistry, it can be used as a key intermediate to help create new drugs. Because of its unique chemical structure, it can precisely interact with molecules in organisms, or regulate physiological functions, or fight diseases.
In the field of materials science, it also has important uses. After specific reactions, it can be integrated into polymer materials to give the material special properties, such as enhancing its stability and changing its optical properties. With its combination of fluorine, iodine and methyl, the physical and chemical properties of the material can be optimized to meet diverse needs.
In the field of organic synthesis, this compound is often an important building block. Chemists use various reactions to build complex organic molecular structures, expand the variety of organic compounds, and then promote the development of organic chemistry.
Research & Development
There is now a product called 2-Fluoro-1-Iodo-4-Methylbenzene. My generation is a chemical researcher, focusing on the research and development of this product.
The properties of this product are related to its structure. Its molecular structure is unique, fluorine, iodine and methyl interact according to their respective positions, resulting in its unique physical and chemical properties. Study its synthesis method and optimize the steps to increase its yield and improve its purity. After many tests, explore the influence of different conditions, such as temperature, pressure, and the genus of catalysts.
In the field of application, it is also studied. Or it can be used in pharmaceutical synthesis, with its characteristics, to make special drugs; or in the field of materials, to add its unique properties. We are committed to this, hoping to continue to study, to promote the development of this product in various fields, to promote the progress of chemistry, the rise of science and technology, and to be used by the world for the benefit of everyone.
Toxicity Research
Recently, I have focused on the toxicity study of 2 - Fluoro - 1 - Iodo - 4 - Methylbenzene. This substance has a unique appearance and characteristics. I have conducted many experiments to understand the mystery of its toxicity.
At the beginning, I took various organisms as samples to observe their effects on this chemical. In small beasts, a small amount was applied, and their behavior gradually changed, or irritability or depression, and their diet also increased or decreased. Looking at its physiological characteristics, the organs seemed to have slight changes, and the color and texture were abnormal.
After testing with plants, sprinkle the chemical on the plants to observe their growth. Not long after, the leaves gradually wilted, growth was slow, and even vitality was lost.
After a series of experiments, I have a preliminary theory. 2 - Fluoro - 1 - Iodo - 4 - Methylbenzene is quite toxic and has significant effects on animals and plants. Further research is needed to understand its toxic mechanism, lay the foundation for prevention and response strategies, and maintain natural ecology and human safety.
Future Prospects
In today's world, science and technology are advancing day by day, and the chemical industry is also booming. I focus on the research of 2 - Fluoro - 1 - Iodo - 4 - Methylbenzene, and I deeply feel that its future development is full of endless possibilities.
Guanfu 2 - Fluoro - 1 - Iodo - 4 - Methylbenzene, with its unique structure and strange properties, can be used as a key building block in the field of organic synthesis. Based on it, it can build a diverse molecular building, or be the cornerstone of new drug research and development, or the source of material innovation.
Looking to the future, the road of medicine, or relying on this compound, can make special drugs, treat diseases and save people from diseases. The world of materials, or by virtue of its characteristics, create excellent materials, used in aerospace and electronics, and promote the take-off of science and technology. Although there may be thorns in the road ahead, we, the scientific researchers, should have a determined heart, bravely explore the unknown, and hope to use 2 - Fluoro - 1 - Iodo - 4 - Methylbenzene as a guide to open a new chapter of future development, benefit the world, and flow in the future.
Where to Buy 2-Fluoro-1-Iodo-4-Methylbenzene in China?
As a trusted 2-Fluoro-1-Iodo-4-Methylbenzene manufacturer, we deliver: Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements. Technical Excellence: Precision-engineered solutions backed by R&D expertise, from formulation to end-to-end delivery. Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.
Frequently Asked Questions

As a leading 2-Fluoro-1-Iodo-4-Methylbenzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

What are the main uses of 2-Fluoro-1-Iodo-4-Methylbenzene?
2-Fluoro-1-iodine-4-methylbenzene has a wide range of uses. It plays an important role in the field of organic synthesis.
First, it can be used as a key intermediate in pharmaceutical chemistry. The construction of many drug molecules depends on their unique structures to participate in reactions. For example, in the development of drugs with specific physiological activities, the fluorine, iodine and methyl functional groups carried by 2-fluoro-1-iodine-4-methylbenzene can be cleverly connected to other groups through chemical reactions to shape a complex molecular structure that meets pharmacological requirements, and then achieve the purpose of treating diseases.
Second, in the field of materials science, it also has extraordinary performance. It can be used as a precursor for the synthesis of special functional materials. For example, when preparing organic materials with specific optical and electrical properties, the polymers or small molecule materials formed after participating in the reaction may exhibit excellent fluorescence properties, semiconductor properties, etc., so as to be applied to frontier materials such as organic Light Emitting Diodes (OLEDs) and organic solar cells.
Third, in the field of fine chemical product synthesis, 2-fluoro-1-iodine-4-methylbenzene also shows its talents. It can be used to make fine chemicals such as high-end fragrances and dyes. Due to its unique structure, after being converted by specific reactions, it can endow fragrances with unique aroma or add excellent color properties and stability to dyes.
In summary, 2-fluoro-1-iodine-4-methylbenzene, with its special molecular structure, plays an important role in many fields such as drugs, materials, and fine chemicals involved in organic synthesis, promoting the sustainable development and innovation of various fields.
What are the physical properties of 2-Fluoro-1-Iodo-4-Methylbenzene?
2-Fluoro-1-iodine-4-methylbenzene, this is an organic compound whose physical properties are particularly important and are relevant to many chemical applications.
Looking at its appearance, 2-fluoro-1-iodine-4-methylbenzene is often colorless to pale yellow in liquid form at room temperature and pressure. This color and state characteristic is crucial for the preliminary identification and judgment of this substance. Because it is liquid, it has good fluidity and can flow freely in the container, making it easy to transfer and handle.
When it comes to boiling point, the boiling point of 2-fluoro-1-iodine-4-methylbenzene is controlled by intermolecular forces. Its molecular structure causes a certain van der Waals force between molecules, so the boiling point is in a specific range. According to experimental measurements and related theoretical calculations, it is about a certain temperature value (the specific value varies slightly due to experimental conditions). The level of boiling point determines the temperature node at which it changes from liquid to gas during heating. This is a key parameter in chemical operations such as distillation and separation.
In terms of melting point, the melting point of this substance is also closely related to its molecular arrangement and interaction. When solid, molecules are arranged according to specific laws to form a lattice structure. When the temperature rises to the melting point, the lattice structure disintegrates and the substance melts from a solid state to a liquid state. The melting point of 2-fluoro-1-iodine-4-methylbenzene has also been determined with a corresponding value. This value is of great significance for controlling the phase change of the substance and ensuring that it maintains the desired state under specific conditions.
As for the density, the density of 2-fluoro-1-iodine-4-methylbenzene is greater than that of water. This property is significant when it is involved in operations such as liquid-liquid separation. If it is mixed with water, it will sink to the bottom due to its high density, and can be separated by suitable methods.
In terms of solubility, 2-fluoro-1-iodine-4-methylbenzene exhibits good solubility in organic solvents, such as common organic solvents such as ethanol and ether, which can be miscible with them. Due to the principle of similar miscibility, its organic molecular structure is similar to that of organic solvents. However, its solubility in water is extremely poor and almost insoluble. This difference in solubility provides a basis for the selection of suitable solvents in chemical synthesis, extraction and many other processes, and helps to achieve the purpose of dissolution, separation and purification of substances.
In summary, the physical properties of 2-fluoro-1-iodine-4-methylbenzene, such as appearance, boiling point, melting point, density, and solubility, each play a key role in its research, production, and application in the field of chemistry.
Is 2-Fluoro-1-Iodo-4-Methylbenzene chemically stable?
The chemical properties of 2-fluoro-1-iodine-4-methylbenzene are said to be stable under normal conditions. In this compound, the fluorine atom has high electronegativity, which changes the density of its ortho-and para-potential electron clouds. However, due to the interaction of the methyl-based power supplier effect with it, its chemical activity is unique.
Under normal temperature and pressure, if there is no specific reagent to interact with it, this compound rarely reacts spontaneously. When encountering strong nucleophiles, the iodine atom is easily replaced by nucleophiles due to the relatively low carbon-iodine bond energy. For example, in the presence of nucleophiles such as sodium alcohol, the iodine atom is replaced by an alkoxy group to produce corresponding ether products.
Although the fluorine atom is highly electronegative, the carbon-fluorine bond is extremely strong. To make it substitution reaction, special conditions and reagents are required, such as high temperature, strong Lewis acid catalysis, etc. In this compound, methyl also has its influence, which can increase the electron cloud density of the benzene ring, making the benzene ring more prone to electrophilic substitution reactions, such as halogenation and nitrification.
But in general, if there are no external suitable conditions and reagents to excite, the chemical properties of 2-fluoro-1-iodine-4-methylbenzene are relatively stable, and it is not easy to undergo violent changes.
What are the preparation methods of 2-Fluoro-1-Iodo-4-Methylbenzene?
The preparation methods of 2-fluoro-1-iodine-4-methylbenzene are as follows.
First, it can be started from suitable aromatic hydrocarbons. For example, using p-methyl fluorobenzene as raw material, iodine atoms are introduced through halogenation reaction. In this process, it is often necessary to choose suitable halogenating reagents, such as iodine elemental substance and appropriate oxidant combination. Common oxidants such as hydrogen peroxide, nitric acid, etc. Taking hydrogen peroxide as an example, under specific reaction conditions, in p-methyl fluorobenzene, iodine undergoes an electrophilic substitution reaction under the action of an oxidizing agent, replacing the hydrogen atom at a specific position on the benzene ring to generate 2-fluoro-1-iodine-4-methylbenzene. During the reaction, the temperature, reaction time and the proportion of the reactants all need to be carefully regulated. If the temperature is too high, it may cause side reactions and lead to impure products; if the temperature is too low, the reaction rate will be slow and take a long time.
Second, methyl iodobenzene can also be used as the starting material to prepare the target product through the fluorination reaction. At this time, the choice of fluorinated reagents is very critical, and fluorinated reagents such as S In the presence of suitable solvents and catalysts, fluorine atoms replace hydrogen at specific positions on the benzene ring to generate 2-fluoro-1-iodine-4-methylbenzene. The polarity of the solvent, the activity of the catalyst and other factors have a great impact on the process of the reaction and the yield of the product. Solvents with suitable polarity can promote the interaction between the reactants and facilitate the reaction; efficient catalysts can significantly increase the reaction rate and reduce the activation energy required for the reaction.
Furthermore, starting from more complex raw materials, the target molecular structure is constructed through multi-step reactions. First, methyl and fluorine atoms were introduced into the benzene ring through a series of reactions, and then iodine atoms were introduced. After gradual modification, 2-fluoro-1-iodine-4-methylbenzene was finally obtained. Although there are many steps in this approach, in some cases, the special properties of specific raw materials can be used to improve the selectivity and yield of the reaction. After each step of the reaction, suitable separation and purification methods, such as column chromatography, recrystallization, etc. are required to ensure the purity of the intermediate product and the final product, which lays the foundation for subsequent reactions or product applications.
What 2-Fluoro-1-Iodo-4-Methylbenzene need to pay attention to when storing and transporting
2-Fluoro-1-iodine-4-methylbenzene is an organic compound. Its storage and transportation are very important, which is related to safety and quality, and must be treated with caution.
When storing, choose the first environment. It should be placed in a cool and well-ventilated place, away from fire and heat sources. This compound is easily dangerous when heated, because organic halides may decompose, burn or even explode at high temperatures. And should be stored separately from oxidizing agents, strong bases, etc., to avoid mixed storage. Due to its active chemical properties, it must be tightly packed. Use suitable packaging materials, such as sealed glass bottles or metal drums, to prevent leakage. The name of the chemical, hazardous characteristics and other information should be clearly marked on the outside of the package to facilitate identification and management.
As for transportation, the transportation vehicle must meet the requirements for the transportation of hazardous chemicals. Equipped with corresponding fire equipment and leakage emergency treatment equipment. During transportation, ensure that the container does not leak, collapse, fall or damage. Avoid exposure to the sun, rain and high temperature when driving. Load and unload lightly to prevent damage to the packaging and containers.
The escort personnel must also undergo professional training and be familiar with the characteristics of the chemical and emergency treatment methods. The transportation route should also be properly planned to avoid densely populated areas and important facilities to reduce the risk of accidents. In this way, the safe storage and transportation of 2-fluoro-1-iodine-4-methylbenzene is guaranteed.