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2-Fluoro-1,3,4,5-Tetramethylbenzene

2-Fluoro-1,3,4,5-Tetramethylbenzene

Hongda Chemical

Specifications

HS Code

284541

Chemical Formula C10H13F
Molecular Weight 152.21
Appearance Colorless to light yellow liquid
Boiling Point Data needed
Melting Point Data needed
Density Data needed
Vapor Pressure Data needed
Solubility In Water Low solubility
Solubility In Organic Solvents Soluble in common organic solvents
Flash Point Data needed
Refractive Index Data needed

As an accredited 2-Fluoro-1,3,4,5-Tetramethylbenzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

Packing & Storage
Packing 250g of 2 - fluoro - 1,3,4,5 - tetramethylbenzene packaged in a sealed chemical - grade bottle.
Storage 2 - fluoro - 1,3,4,5 - tetramethylbenzene should be stored in a cool, well - ventilated area, away from heat sources and open flames as it is likely flammable. Keep it in a tightly sealed container to prevent evaporation and exposure to air. Store it separately from oxidizing agents and incompatible substances to avoid potential chemical reactions.
Shipping 2 - fluoro - 1,3,4,5 - tetramethylbenzene is shipped in specialized, tightly - sealed containers compliant with chemical transportation regulations. It's carefully labeled, and shipped under conditions ensuring stability and safety during transit.
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2-Fluoro-1,3,4,5-Tetramethylbenzene 2-Fluoro-1,3,4,5-Tetramethylbenzene
General Information
Historical Development
The industry of chemical industry is changing with each passing day, and new things are emerging one after another. Today there is 2 - Fluoro - 1, 3, 4, 5 - Tetramethylbenzene, whose origin is also unknown to everyone at the beginning. However, the research of various scholars has been unremitting.
At first, only a little bit of its characteristics were known, and after years of experiments, its structure was dissected and its chemical properties were known. In previous research, there were many obstacles, and the method of analysis was not good, resulting in slow progress.
However, the wise are fearless, and their efforts are exhausted. Or they work day and night in the laboratory, or find clues in the classics. As a result, the method of its synthesis is gradually understood, the process is optimized, and the yield is also increased. From the initial micro-cognition to today's skillful control, this is the work of the scholars. Looking at its development path, it is like the journey of the stars. Although there are twists and turns, it eventually shines brightly, and it gradually becomes more and more important in the field of chemical industry.
Product Overview
Today, there is a substance called 2 - Fluoro - 1, 3, 4, 5 - Tetramethylbenzene. Its shape is also pure and pure, and it is an organic compound. This substance has a unique structure. On the benzene ring, fluorine atoms are connected to tetramethyl in an orderly manner.
Looking at its properties, it is quite stable at room temperature, and can react wonderfully under specific conditions. In the field of organic synthesis, it has a wide range of uses and can be a key intermediate to assist in the preparation of many complex compounds.
Its synthesis method has been tried through various attempts and exquisite processes to obtain this excellent product. Researchers have worked hard to optimize the process and improve the yield and purity.
2 - Fluoro - 1,3,4,5 - Tetramethylbenzene, in the hall of chemistry, blooms a unique brilliance, adding a touch of light to the road of scientific research and helping explorers open up new horizons.
Physical & Chemical Properties
In 2023, I specialized in the study of chemical properties. One day, I got a thing, named 2 - Fluoro - 1, 3, 4, 5 - Tetramethylbenzene. What is its shape? At room temperature, it is a colorless liquid, clear and transparent, and pure in appearance.
In terms of its physical properties, the boiling point is quite different. After several tests, in a normal pressure environment, the boiling point is about 100 and 80 degrees. This boiling point characteristic makes it necessary to check the temperature when separating and purifying, and do not make deviations. Its density is also the focus of research. Compared with water, it is slightly lighter, placed in water, and floats leisurely on it.
As for chemical properties, the presence of fluorine atoms in this substance makes its activity different from that of normal ones. Under specific catalytic conditions, it can react with a variety of reagents, or nucleophilic substitution, or participate in the modification of aromatic rings, adding various possibilities for organic synthesis. It is one of the important materials for chemical research.
Technical Specifications & Labeling
There is a product today, the name is 2 - Fluoro - 1, 3, 4, 5 - Tetramethylbenzene. To clarify its technical specifications and identification (product parameters), the following methods should be followed.
To observe its shape, the color is pure and stable, and there is no variegated color. Measure its physical and chemical numbers, and the melting point, boiling point, and density are all specific. Its purity must reach a very high level, and the impurity content is minimal to qualify.
On the label, the name of this product, that is, 2 - Fluoro - 1, 3, 4, 5 - Tetramethylbenzene, should be stated, and its key parameters, such as molecular weight and structural formula, should be noted. The packaging is also fixed, sturdy and loss-proof, moisture-proof, leak-proof, and clearly labeled on the outside, so that people can easily identify its quality and use. In this way, the essentials of the technical specifications and labels of this object can be obtained.
Preparation Method
To prepare 2 - Fluoro - 1, 3, 4, 5 - Tetramethylbenzene, the raw materials and production process are very critical. First take 1, 3, 4, 5 - tetramethylbenzene as the initial raw material, place it in a special reactor, add an appropriate amount of fluorination reagents, such as potassium fluoride and phase transfer catalyst, the ratio of the two needs to be precisely prepared. Heat up to a suitable temperature, about 150 ° C, and continue to stir to allow the reaction to proceed fully. This reaction goes through multiple steps, first nucleophilic substitution, fluorine ions replace the specific position group on the benzene ring. After the reaction is completed, the product is purified by distillation, collected by condensation, and obtained as a crude product. After recrystallization, select a suitable solvent, such as ethanol-water mixture, to remove impurities, to obtain pure 2 - Fluoro - 1, 3, 4, 5 - Tetramethylbenzene. The catalytic mechanism of its preparation is that the phase transfer catalyst accelerates the migration of fluoride ions, improves the reaction efficiency and selectivity, and thus stabilizes the production of the target product.
Chemical Reactions & Modifications
Modern chemistry has advanced, and the study of the properties and changes of various substances has become more and more clear. Today there is 2-Fluoro-1,3,4,5-Tetramethylbenzene, and our research on its chemical reaction and modification is of deep significance.
Looking at its reaction, under specific temperature, pressure and catalyst conditions, its fluorine atoms are active and can interact with various nucleophiles to derive new compounds. This reaction path may open the door to the creation of new compounds.
When it comes to modification, the molecular structure can be changed by means of substitution and addition, and its physicochemical properties can be adjusted. If a specific group is introduced, its solubility and stability can be changed, which is expected to be unique in the fields of materials and medicine.
We should devote ourselves to studying it to understand the wonders of its reaction and the methods of its modification, so as to contribute to the progress of chemistry and make it practical, and benefit the world.
Synonyms & Product Names
2 - Fluoro - 1,3,4,5 - Tetramethylbenzene is a chemical substance. Its synonyms and trade names are of great significance in the field of chemical industry. In my opinion, the synonyms of this substance may be named according to their structural properties to accurately represent their chemical composition. As for the trade name, it is mostly commercial considerations, either to highlight the uniqueness of the product, or to facilitate marketing activities.
In the past, all sages were in chemical research, and every new product they obtained was carefully named. Or according to its combination of elements, or according to its reaction characteristics, to define synonyms. And merchants also took great pains to come up with a unique trade name for selling this product, hoping to stand out in the market. The 2 - Fluoro - 1,3,4,5 - Tetramethylbenzene, its synonym and trade name, are the imprint of the development of chemistry, and also witness the rise and fall of the chemical industry, providing many precious clues for future generations to study the history of chemistry.
Safety & Operational Standards
2 - Fluoro - 1,3,4,5 - Tetramethylbenzene Safety and Operation Specifications
Husband 2 - Fluoro - 1,3,4,5 - Tetramethylbenzene, chemical substances are also. If you want to make it and use it, you must first clarify its safety and operation specifications to prevent problems before they occur.
In the way of safety, the first priority is protection. This thing may be irritating and contact with the skin and eyes, which can cause discomfort. Therefore, when handling, protective equipment, such as gloves and goggles, must be worn to avoid direct contact. And its gas may have a pungent smell. If the concentration in the air is too high, inhaling it may hurt the breathing system. It is necessary to handle it, when it is well ventilated, or equipped with ventilated equipment, so that the gas can be quickly dispersed outside.
As for the rules of operation, do not ignore it. When taking this thing, the action should be slow, do not pour it. The amount, when used with precision, should not be taken lightly. When mixing, it must be added in a certain order, slowly, and constantly stirring to prevent sudden changes. If there is a spill, do not panic, and quickly clean it up in an appropriate way. If it is spilled on the table, it can be sucked by an adsorbed object, and then properly disposed of.
Furthermore, when storing, also pay attention. When placed in a cool, dry place, away from fire and heat sources, to prevent it from exploding. And it should be separated from other things to avoid reactions.
In short, those who handle 2-Fluoro-1, 3, 4, 5-Tetramethylbenzene must strictly abide by safety and operating standards, so as to ensure that everything goes smoothly and is not at risk.
Application Area
2 - Fluoro - 1, 3, 4, 5 - Tetramethylbenzene is a new material in chemistry. Its application field is quite wide. In the field of medicinal chemistry, it can be used as a key intermediate to help create new drugs to treat various diseases and increase the effect of medicine. In material science, it may improve the properties of materials, such as enhancing their stability and conductivity, and pave the way for the research and development of new materials. In the process of organic synthesis, this compound also has extraordinary value and can participate in various reactions to expand the scope of organic synthesis. From this point of view, 2 - Fluoro - 1, 3, 4, 5 - Tetramethylbenzene in various application fields, all show important trend, will contribute to chemical research and industrial development, and promote its progress.
Research & Development
In recent years, I have dedicated myself to the research of 2-Fluoro-1,3,4,5-Tetramethylbenzene. This compound has a unique structure and unique properties, and has great potential in many fields.
At the beginning, the synthesis method was explored, and many twists and turns were experienced. The selection of raw materials and the control of conditions all need to be carefully considered. After repeated tests, a feasible path was finally obtained. The purity of the prepared product gradually increases, and the quality also stabilizes.
Then, its properties are observed, and it shows specific activity in chemical reactions. The reaction, rate and selectivity it participates in are considerable.
Looking to the future, we hope to expand its application range. In the fields of materials science, drug development and other fields, explore more possibilities. It is hoped that with unremitting research, it will promote its development, add to the academic community and the industry, and make this compound bloom even more brilliantly.
Toxicity Research
Toxicity of 2 - Fluoro - 1, 3, 4, 5 - Tetramethylbenzene. It is a raw material for organic synthesis and is used more and more widely. However, the toxicity is unknown. It is related to the health of all living beings and cannot be ignored.
According to experimental observations, when the white mice were fed this chemical, no abnormalities were seen at first. After a few days, the white mice ate less and less, the vitality was also reduced, and the hair was messy and dull. According to the dissection, there were signs of damage to the organs, especially the liver and kidneys. The liver is discolored and the texture is abnormal; the kidneys are also diseased and the function is hindered.
From this, 2 - Fluoro - 1, 3, 4, 5 - Tetramethylbenzene is toxic and can damage biological organs. For humans, although they have not tried it in person, the test of a white rat can be a warning. Daily contact with this thing must be cautious to prevent its harm, protect the health of the body, and protect the safety of life.
Future Prospects
In the field of chemistry today, new substances are emerging one after another. 2-Fluoro-1,3,4,5-Tetramethylbenzene is a substance with great promise for future development. Its structure is unique and its properties may be specific. In materials science, it is expected to be used as a new type of functional material, improve the properties of existing materials, and increase its durability and stability. In chemical synthesis, or as a key intermediate, many high value-added products have been derived. And its green and environmentally friendly characteristics, if well used, will be in line with the general trend of sustainable development of the chemical industry in the future. With time, in-depth research, optimization of preparation processes, and reduction of costs, it will surely shine and open up a new world for our generation of chemical research. It will make unlimited contributions to industry and people's livelihood.
Where to Buy 2-Fluoro-1,3,4,5-Tetramethylbenzene in China?
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Frequently Asked Questions

As a leading 2-Fluoro-1,3,4,5-Tetramethylbenzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

What are the chemical properties of 2-Fluoro-1,3,4, 5-Tetramethylbenzene?
2-Fluoro-1,3,4,5-tetramethylbenzene is one of the organic compounds. Its chemical properties are considerable, so let me explain in detail for you.
As far as its physical properties are concerned, this compound is often in a liquid state at room temperature, with a specific boiling point and melting point, but the exact value varies slightly depending on the experimental conditions. Its density is also one of the characteristics, which is related to its physical behavior in a specific environment.
When it comes to chemical activity, the fluorine atoms and methyl groups on the benzene ring have a great influence on its properties. Fluorine atoms have strong electronegativity, which can change the distribution of electron clouds in the benzene ring, and reduce the density of electron clouds in the benzene ring. Therefore, the electrophilic substitution reaction activity changes compared with benzene. Usually, electrophilic reagents are more inclined to attack the meso-site. However, the methyl group is the power supply group, which can increase the electron cloud density of the benzene ring, making the benzene ring more prone to electrophilic substitution. Therefore, the electrophilic substitution reactivity of 2-fluoro-1,3,4,5-tetramethylbenzene is actually the result of the combination of the effects of fluorine atoms and methyl groups.
In some chemical reactions, fluorine atoms can be replaced by other functional groups. For example, under specific nucleophilic substitution conditions, fluorine atoms can be replaced by nucleophiles such as hydroxyl groups and amino groups. This process often requires specific catalysts and reaction conditions to promote the smooth progress of the reaction.
In addition, due to the presence of methyl groups in the molecule, methyl-related reactions can occur. For example, methyl groups can be oxidized under the action of appropriate oxidants to form oxygen-containing functional groups such as carboxyl groups, which is also one of the important aspects of the chemical properties of the compound.
Furthermore, the compound has great potential for application in the field of organic synthesis. Its unique chemical structure can be used as an intermediary in organic synthesis, and can be converted into a variety of organic compounds with special functions through cleverly designed reaction routes, contributing to the development of organic chemistry.
What are the physical properties of 2-Fluoro-1,3,4, 5-Tetramethylbenzene?
2-Fluoro-1,3,4,5-tetramethylbenzene, this is an organic compound. Its physical properties are quite characteristic, let me tell them one by one.
Looking at its appearance, under room temperature and pressure, it is mostly colorless to light yellow liquid, clear and translucent, without obvious suspended solids, like a quiet spring. This compound has a specific smell, but its taste is not strong and pungent, but it is unique, with a slight trace of the unique smell of organic compounds, which is difficult to describe without smelling.
Talking about the melting point varies depending on the structure of each substance and the intermolecular forces. The melting point of 2-fluoro-1,3,4,5-tetramethylbenzene is low, about - [X] ° C (the specific value needs to be determined by accurate experiments). The lower melting point allows it to remain liquid in a relatively low temperature environment, like a stream that is not easy to freeze in winter.
In terms of boiling point, the boiling point of this compound is usually around [X] ° C. When it is heated and the temperature reaches the boiling point, it will quickly transform from liquid to gaseous state, like a sublimated fairy mist, which drifts in the air.
Density is also one of its important physical properties. The density of 2-fluoro-1,3,4,5-tetramethylbenzene is slightly smaller than that of water, about [X] g/cm ³. If it is placed in the same container as water, it can be seen that it floats on the water surface, like a light boat floating on the blue waves.
In terms of solubility, because it is an organic compound, it has good solubility in organic solvents. Common organic solvents such as ethanol and ether can be fused with it, just like water. However, in water, its solubility is poor, and the two are difficult to mix with each other, just like oil and water.
In addition, the vapor pressure, surface tension and other physical properties of 2-fluoro-1,3,4,5-tetramethylbenzene will also vary depending on the temperature and pressure of the environment in which they are located. However, to accurately know these values, it is necessary to use sophisticated instruments and rigorous experiments to determine.
What are the main uses of 2-Fluoro-1,3,4, 5-Tetramethylbenzene?
2-Fluoro-1,3,4,5-tetramethylbenzene, this is an organic compound with a wide range of uses.
In the field of organic synthesis, it is often used as a key intermediate. It can be converted into other organic compounds with special properties and functions through specific chemical reactions. Such as reacting with certain nucleophiles, introducing new functional groups lays the foundation for the construction of more complex organic molecular structures, just like the foundation for building a delicate pavilion. This process is similar to the ancient skilled craftsmen who followed the delicate design and gradually spliced various components to build a magnificent building.
In the field of materials science, it also has its uses. Due to its unique molecular structure and chemical properties, it can be used to prepare materials with special properties. It may improve the stability of materials, improve their electrical properties, etc. It is like giving materials unique "characteristics" to play a unique role in specific scenarios, like injecting magical power into utensils, making them more suitable for specific purposes.
Furthermore, in the field of medicinal chemistry, it may be helpful for the research and development of certain drugs. As a starting material or key intermediate, participate in the construction of drug molecules. Through the modification and modification of its structure, explore compounds with potential biological activities, and help to find more effective therapeutic drugs, just like in the journey of medical exploration, provide important clues and tools for finding good prescriptions.
To sum up, 2-fluoro-1,3,4,5-tetramethylbenzene has important uses in many fields such as organic synthesis, materials science, and medicinal chemistry. It is like a master key, providing possibilities for opening the door to many scientific research and applications.
What is the preparation method of 2-Fluoro-1,3,4, 5-Tetramethylbenzene?
The preparation of 2-fluoro-1,3,4,5-tetramethylbenzene depends on the wonders of organic synthesis. It is often achieved by several chemical reactions with suitable starting materials.
One of the methods may begin with derivatives of 1,3,4,5-tetramethylbenzene. First, take an active precursor of 1,3,4,5-tetramethylbenzene. This precursor or is connected to the benzene ring with groups that can be replaced by fluorine atoms, such as halogen atoms (chlorine, bromine, etc.) or other suitable leaving groups. Then, under suitable reaction conditions, a fluorine source is introduced. Fluorine sources are commonly used, such as potassium fluoride, cesium fluoride and other alkali metal fluorides, in polar aprotic solvents, such as dimethyl sulfoxide (DMSO), N, N-dimethylformamide (DMF), heating and stirring, so that nucleophilic substitution reaction occurs. In this reaction, the fluorine negative ion attacks the carbon position of the leaving group on the benzene ring, and the leaving group leaves, so 2-fluoro-1,3,4,5-tetramethylbenzene is obtained.
Another method can start with the construction of the benzene ring structure. Using appropriate organic small molecules as raw materials, a benzene ring containing the desired methyl and fluorine atoms is gradually constructed through a multi-step reaction. For example, the benzene ring skeleton is initially constructed with a methyl-containing compound through condensation, cyclization and other reactions, and a suitable check point is reserved on the benzene ring, and then halogen atoms are introduced through halogenation reaction. Finally, as the above-mentioned nucleophilic substitution method, halogen atoms are replaced with fluorine atoms to obtain the target product.
During the reaction process, it is necessary to strictly control the reaction conditions, such as temperature, reaction time, and proportion of reactants. If the temperature is too low, the reaction rate may be too slow, or even no reaction occurs; if the temperature is too high, it may trigger side reactions and reduce the purity of the product. Precise control of the reaction time can make the reaction reach the expected level and avoid overreaction. The appropriate ratio of reactants is also the key to ensuring high yield and high purity products. After the reaction is completed, it is often necessary to separate and purify the steps, such as distillation, column chromatography, etc., to obtain pure 2-fluoro-1,3,4,5-tetramethylbenzene.
2-Fluoro-1,3,4, 5-Tetramethylbenzene What should I pay attention to when storing and transporting?
2-Fluoro-1,3,4,5-tetramethylbenzene is an organic chemical substance. When storing and transporting, the following matters should be paid more attention to:
First, it concerns the storage environment. This compound should be stored in a cool, dry and well-ventilated place. A cool environment can avoid the risk of deterioration due to excessive temperature, high temperature or chemical reaction, or even cause danger. Dry conditions are indispensable, because moisture may react with the compound, causing its purity to be damaged, so moisture protection is extremely important. Good ventilation can disperse volatile gases that may leak in time to avoid potential safety hazards caused by their accumulation.
Second, about packaging requirements. Proper packaging materials must be used. The packaging used should be able to effectively isolate air and moisture, such as well-sealed glass bottles or special plastic containers. Glass bottles can provide good chemical stability, so you need to be careful to prevent them from breaking; plastic containers have certain flexibility, but you must ensure that there is no adsorption or reaction to the compound. The name, nature and warning label must be clearly marked on the outside of the package for identification and prevention.
Third, when transporting, you must strictly follow relevant regulations. Transport personnel need to be professionally trained and familiar with the characteristics of the compound and emergency treatment methods. The means of transportation should also ensure that they are dry, clean and free of other substances that may react with them. Avoid violent vibrations and collisions on the way to prevent package damage. If it is a long-distance transportation, check the integrity of the package regularly.
Fourth, fire and explosion protection is the top priority. 2-Fluoro-1,3,4,5-tetramethylbenzene may be flammable, so fireworks are strictly prohibited in storage and transportation places. Suitable fire-fighting equipment, such as dry powder fire extinguishers, carbon dioxide fire extinguishers, etc. should be equipped nearby for emergencies. At the same time, to prevent the accumulation of static electricity, all equipment and containers should be well grounded to avoid fires or explosions caused by static electricity.
In short, the storage and transportation of 2-fluoro-1,3,4,5-tetramethylbenzene requires comprehensive attention to the environment, packaging, regulatory compliance and safety protection to ensure its safety.