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2-Ethoxy-4-Fluorobromobenzene

2-Ethoxy-4-Fluorobromobenzene

Hongda Chemical

Specifications

HS Code

790096

Chemical Formula C8H8BrFO
Molar Mass 219.05 g/mol
Appearance Liquid (usually)
Density Data needed
Boiling Point Data needed
Melting Point Data needed
Solubility In Water Insoluble (estimated, as it's an organic aromatic compound)
Solubility In Organic Solvents Soluble in common organic solvents like ethanol, dichloromethane
Flash Point Data needed
Vapor Pressure Data needed
Refractive Index Data needed

As an accredited 2-Ethoxy-4-Fluorobromobenzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

Packing & Storage
Packing 100g of 2 - ethoxy - 4 - fluorobromobenzene packaged in a sealed glass bottle.
Storage Store 2 - ethoxy - 4 - fluorobromobenzene in a cool, dry, well - ventilated area away from heat sources and ignition sources. Keep it in a tightly closed container made of suitable materials, like glass or certain plastics, to prevent leakage and vapor escape. Avoid storing near oxidizing agents or reactive substances to prevent chemical reactions.
Shipping 2 - ethoxy - 4 - fluorobromobenzene, a chemical, is shipped in specialized, well - sealed containers to prevent leakage. It adheres to strict hazardous materials shipping regulations, ensuring safe transport due to its potentially harmful nature.
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2-Ethoxy-4-Fluorobromobenzene 2-Ethoxy-4-Fluorobromobenzene
General Information
Historical Development
Those who have heard of the goodness of ancient times are chemists, who are exhausted and complete, in order to explore the mysteries of matter. In today's words, 2 - Ethoxy - 4 - Fluorobromobenzene is a thing that scholars have never known in the past.
At the beginning, the chemical technology was not refined, and everyone was still shallow in the way of organic synthesis. However, Zhu Xian worked tirelessly to understand the mechanism of various reactions. As time goes by, the instruments become more refined, the theory is more and more prepared, and the method of organic synthesis is advancing.
Some wise people pay attention to compounds containing fluorine, bromine and ethoxyl groups. After many attempts, they use exquisite methods to make the elements properly combined, and finally get 2 - Ethoxy - 4 - Fluorobromobenzene. Since its birth, it has gradually shown its use in the fields of medicine and materials, opening up a new path for future research and application. Its development process is the cohesion of the efforts of scholars of chemistry, and it is also one of the evidences of chemical progress.
Product Overview
Regarding 2-ethoxy-4-fluorobromobenzene
There is a substance named 2-ethoxy-4-fluorobromobenzene. Its shape may be a colorless liquid with a special gas. The structure of this substance is exquisite, and the ethoxy group is cleverly connected to the benzene ring with fluorine and bromine atoms.
In terms of properties, its chemical activity is unique due to the conjugate system of the benzene ring and the electronic effects of fluorine, bromine and ethoxy groups. It can play an important role in many chemical reactions, such as nucleophilic substitution reactions. Because of its active halogen atoms, it is easy to be attacked by nucleophilic reagents, and a variety of new compounds are derived.
Furthermore, its physical properties are also considerable. The values of boiling point and melting point are related to its phase transition under different conditions. In terms of solubility, it may have a good dissolution state in specific organic solvents, which is of great significance in separation, purification and reaction medium selection.
2-ethoxy-4-fluorobromobenzene has a wide range of uses in the field of organic synthesis. It can be used as a key intermediate to help synthesize fine chemicals such as drugs and materials, opening up new paths for chemical research and industrial production.
Physical & Chemical Properties
Today there is a substance called 2 - Ethoxy - 4 - Fluorobromobenzene. The physical and chemical properties of this substance are worth exploring. Its appearance may be a colorless to light yellow liquid with a special odor. Looking at its solubility, in organic solvents, it may have a certain solubility, but in water, it may be difficult to dissolve.
In terms of its chemical properties, its activity may be different due to the presence of functional groups such as bromine and fluorine. The bromine atom is on the benzene ring, and may participate in the nucleophilic substitution reaction, providing a checking point for the reaction. The fluorine atom has strong electronegativity, which affects the distribution of the electron cloud of the molecule, or causes selective changes in the reaction.
Its physical constants such as boiling point and melting point are also key. The boiling point is in a specific range due to the force between molecules, and the melting point is related to the arrangement of molecules. The study of the physical and chemical properties of this substance may have important guiding significance in the fields of chemistry, medicine and so on.
Technical Specifications & Labeling
Technical specifications and labeling (product parameters) of 2-ethoxy-4-fluorobromobenzene
This 2-ethoxy-4-fluorobromobenzene is an important raw material for organic synthesis. Its technical specifications are related to purity and impurity limits. The purity needs to be above 95, and impurities such as moisture and metal ions are strictly limited.
In terms of labeling, the packaging should clearly state the product name, chemical formula C-H-BrFO, molecular weight 235.05, and warning labels, such as flammable, harmful, etc. The product parameters should also be listed in detail. The melting point, boiling point, and density are all fixed. The melting point is about -10 ° C, the boiling point is about 220 ° C, and the density is about 1.58 g/cm ³. These specifications and labels are the foundation of product quality and use safety, and practitioners must abide by them.
Preparation Method
The method of making 2-ethoxy-4-fluorobromobenzene is the most important raw material and process. Take fluorobenzene as the beginning, after bromination, use a specific agent and temperature to make bromine into the fluorobenzene to get 4-fluorobromobenzene.
Then, when 4-fluorobromobenzene meets sodium ethyl alcohol, in the environment of suitable temperature and pressure, it is replaced by nucleophilic, ethoxyl bromide, into 2-ethoxy-4-fluorobromobenzene.
This process has accurate temperature control, appropriate material ratio, and can increase yield. And the setting of the reaction device and the adjustment of the stirring rate are all related to the purity of the product. In addition, the post-treatment method is also heavy. After extraction and distillation, high-purity 2-ethoxy-4-fluorobromobenzene is obtained to prepare for various uses.
Chemical Reactions & Modifications
F 2 - Ethoxy - 4 - Fluorobromobenzene is also an organic compound. In the matter of chemical reaction and modification, its theory is profound and practical.
Looking at the reaction, it can be changed by nucleophilic substitution. If you encounter a suitable nucleophilic reagent, a new bond can be formed at the bromine atom, causing molecular structure changes. This is due to the activity of bromine, which is easy to be attacked by nucleophiles.
As for modification, different functional groups can be introduced to reduce its properties. For example, the addition of hydroxyl and amino groups can make the compound have different physical and chemical properties, or increase its solubility, or change its reactivity. It all depends on the chemists to study the mechanism in detail and make good use of techniques to achieve the ideal change. Make this compound in the fields of medicine and materials to develop its capabilities and benefit the world.
Synonyms & Product Names
2-Ethoxy-4-fluorobromobenzene, the synonym and trade name of this substance, is an important item in chemical research. In my pursuit of chemistry, I am well aware of its synonyms and trade names, which can help us accurately recognize objects and communicate freely.
Examine its synonyms, although there are not many complex variants, it is also crucial to be accurate and clear. As for the trade name, it is also used for identification when various chemical products are distributed in the city.
When our chemical researchers explore the properties and uses of 2-ethoxy-4-fluorobromobenzene, both synonyms and trade names are elements that cannot be ignored. Only by clarifying its meaning can we move forward freely in academic discussions and industrial applications, so as to reach the depth of chemical research and promote the good use of this chemical in various fields for the benefit of the world.
Safety & Operational Standards
Safety and Operating Specifications for 2-Ethoxy-4-Fluorobromobenzene
Fu 2-ethoxy-4-fluorobromobenzene is an important substance in chemical research. During the whole process of its experimental operation, safety is the first priority, and the operating specifications must be strictly followed.
For storage, it should be placed in a cool, dry and well ventilated place. This substance is quite sensitive to environmental factors. High temperature and humidity can cause changes in its properties, or even cause safety hazards. Therefore, the warehouse temperature should be controlled within a specific range, and the humidity should not be too high. And it must be separated from oxidants, acids, alkalis and other substances to prevent chemical reactions.
During the operation, the experimenter must take protective measures. Wear protective clothing, which must have good corrosion resistance, which can effectively resist the damage of the substance to the body. Wear protective gloves, the material should be able to withstand the erosion of 2-ethoxy-4-fluorobromobenzene, and avoid direct contact with the skin. Goggles are also indispensable to protect the eyes from possible splashing liquids.
When taking 2-ethoxy-4-fluorobrobenzene, the action should be gentle and precise. After use, the container must be properly sealed to prevent the substance from evaporating. If there is a spilling situation, do not panic, and should be dealt with immediately according to the established procedures. First cover with appropriate adsorbent material to prevent its spread, then collect it carefully and dispose of it according to regulations.
Furthermore, the ventilation equipment of the experimental site must be kept in good working condition at all times. If 2-ethoxy-4-fluorobromobenzene volatilizes in the air, it may cause damage to the respiratory system of the experimenter. Efficient ventilation can discharge harmful gases in time and maintain the air quality of the experimental environment.
In short, in the research and use of 2-ethoxy-4-fluorobromobenzene, safety and operating standards are always followed. Only by strictly adhering to various guidelines can ideal research results be obtained and the personal safety of the experimenter and the safety of the environment can be guaranteed.
Application Area
Today there is a thing called 2-Ethoxy-4-Fluorobromobenzene. This chemical thing has its uses in many fields.
In the field of medicine, it can be used as a key raw material for the synthesis of drugs. With its unique chemical structure and ingenious reaction, it can be used to prepare drugs with specific curative effects, or it can be used to treat certain diseases and treat diseases for patients.
In the world of materials, it also has something extraordinary. It can participate in the synthesis of special materials, so that materials can obtain different properties, such as enhancing their stability and changing their optical properties. It may have important applications in electronic and optical materials, etc., to help materials improve their properties and meet different needs.
From this point of view, 2-Ethoxy-4-Fluorobromobenzene in the application fields of medicine and materials, it is of great value and has considerable prospects.
Research & Development
This research 2 - Ethoxy - 4 - Fluorobromobenzene is related to the great cause of our generation's research and development. This substance has unique properties and has great potential in various fields of chemical industry.
We have studied for a long time to analyze its structure and explore the reaction mechanism. At the beginning, the selection of raw materials is very thoughtful, and it is necessary to weigh the purity, cost and difficulty of obtaining. During the experimental process, the control of conditions is the key, and the temperature, pressure and catalyst dosage all affect the product.
Although there are many obstacles, such as the impurity of the product caused by the frequent generation of side reactions, we have been working tirelessly to optimize the process. After repeated debugging, we have obtained a relatively good method, and the purity and yield of the product have been significantly improved.
With time and continuous refinement of technology, it is expected that 2-Ethoxy-4-Fluorobromobenzene will be widely used in industrial production, promoting the development of the industry and benefiting the people's livelihood.
Toxicity Research
Modern chemical refinement is particularly important for the study of the toxicity of various substances. When it comes to 2-Ethoxy-4-Fluorobromobenzene this substance, the investigation of its toxicity should not be underestimated.
To study the toxicity of this substance, it is necessary to observe the structure of its molecules and explore its sympathies with other substances. Looking at its structure, ethoxy, fluorine atoms and bromine atoms are combined in the benzene ring. This unique structure may lead to special chemical activity.
In living organisms, it may interact with key molecules such as proteins and nucleic acids. For example, fluorine atoms have strong electronegativity, or change the surrounding electron cloud cloth, causing them to combine with biomolecules. Bromine atoms are also active, or involve reactions such as nucleophilic substitution, which disturb the normal physiology of cells.
And the path of its entry into the body is also the focus of the study. Oral, percutaneous or inhalation, different paths have different effects on organisms. Oral entry into the body, or react in the digestive system, damaging gastrointestinal mucosa; percutaneous penetration, or affect skin cell metabolism; inhalation directly invades the respiratory organs, involving the lungs and other important places.
To understand the full picture of its toxicity, multiple methods are needed, animal experiments, cell experiments and theoretical calculations can be confirmed, providing a solid foundation for protection and application.
Future Prospects
Today there is a thing called 2 - Ethoxy - 4 - Fluorobromobenzene. Our generation looks to its future as a chemist, full of hope. This thing may emerge in the field of chemical industry. Its structure is unique and its characteristics are unique. It can be used to create new agents, in medicine, or as a cure for diseases; in the world of materials, or to build novelties.
In the future, science and technology are changing day by day, and the power of research and development is unremitting. We hope that it can solve problems, add vitality to industry, and benefit people's livelihood. Although there may be thorns in the road ahead, the heart of scientific research is perseverance, and it must study physics and never stop studying. It is hoped that this material will bloom brilliantly in the unfinished years, become a treasure of chemical industry, help human progress, be praised by future generations, and create a new situation.
Where to Buy 2-Ethoxy-4-Fluorobromobenzene in China?
As a trusted 2-Ethoxy-4-Fluorobromobenzene manufacturer, we deliver: Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements. Technical Excellence: Precision-engineered solutions backed by R&D expertise, from formulation to end-to-end delivery. Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.
Frequently Asked Questions

As a leading 2-Ethoxy-4-Fluorobromobenzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

What are the main uses of 2-Ethoxy-4-Fluorobromobenzene?
2-Ethoxy-4-fluorobromobenzene, this is an organic compound. It has a wide range of uses and is often used as a key intermediate in the field of medicinal chemistry to create many specific drugs. For example, when developing new drugs for the treatment of specific diseases, its unique structure can be used to build a core framework of drug activity through chemical synthesis steps to promote the drug to achieve the desired therapeutic effect.
In the field of materials science, its role should not be underestimated. It can participate in the preparation of materials with special properties, such as in the synthesis of organic optoelectronic materials, as a basic raw material, endowing materials with specific optoelectronic properties, such as excellent fluorescence properties or good electrical conductivity, to help manufacture high-performance Light Emitting Diodes, solar cells and other optoelectronic devices.
In pesticide chemistry, 2-ethoxy-4-fluorobromobenzene also plays an important role. It can be used as a starting material to synthesize high-efficiency and low-toxicity pesticides through a series of reactions, which is of great significance for crop disease and pest control, can effectively protect crops, and improve crop yield and quality.
In addition, it also plays an important role in the preparation of fine chemical products. It can derive a variety of fine chemicals with special functions, such as special fragrances, additives, etc., adding unique properties and application value to chemical products to meet the needs of different industries and fields for special chemicals.
What are the physical properties of 2-Ethoxy-4-Fluorobromobenzene?
2-Ethoxy-4-fluorobromobenzene is also an organic compound. Its physical properties have a number of characteristics, let me tell them one by one.
This compound is either liquid or solid at room temperature, depending on the specific environmental conditions. Looking at its color, it is often colorless to slightly yellow. When it is pure, it may have a certain sense of transparency, like glass crystal.
On its smell, it may have a special aromatic smell, but this smell is not rich and pungent, but has a certain softness. Although it is different from the ordinary fragrance, it also has its own unique characteristics.
Its melting point is a key physical property. The value of the melting point is the critical temperature at which a substance changes from a solid state to a liquid state. The melting point of 2-ethoxy-4-fluorobromobenzene is specific. At this temperature, the substance is a solid state and has a stable structure. Once the temperature rises above the melting point, it gradually melts into a liquid state. The boiling point is the critical temperature at which the liquid turns into a gas state. At this temperature, the liquid vaporizes violently, and the molecules break free from the liquid phase and escape into the gas phase. The boiling point of this compound is determined by its intermolecular forces, molecular weight, and many other factors.
As for the density, compared to water, it may be different. If the density is greater than water, it will be placed in water and will sink to the bottom; if it is less than water, it will float to the surface. The value of density reflects the mass of its unit volume, which is related to its mixing and delamination with other substances in practical applications.
Solubility is also an important property. In organic solvents, such as ethanol, ether, etc., it may have good solubility and can blend with organic solvents to form a uniform mixture. However, in water, due to the hydrophobic groups in its structure, the solubility is poor, mixed with water, or appears to be delaminated.
In addition, the volatility of 2-ethoxy-4-fluorobromobenzene cannot be ignored. Although it is not a highly volatile substance, under suitable conditions such as temperature and ventilation, some molecules will escape from the surface of the liquid phase and enter the gas phase, which affects the requirements of its storage and use environment.
What is the chemistry of 2-Ethoxy-4-Fluorobromobenzene?
2-Ethoxy-4-fluorobromobenzene is also an organic compound. In its molecular structure, the bromine atom, fluorine atom and ethoxy group are in one place above the benzene ring. The chemical properties of this compound are described as follows:
The properties of halogenated aromatics are first described. The bromine atom is attached to the benzene ring, so that this compound has the typical reaction of halogenated aromatics. In case of nucleophiles, the bromine atom on the benzene ring can be replaced. For example, when co-heated with sodium alcohol, the bromine atom can be replaced by an alkoxy group to form a corresponding ether compound. This is because the electron cloud distribution of the benzene ring makes the bromine atom have a certain activity. Although the activity of the halogen atom in the halogenated alkane is slightly inferior, under appropriate conditions, the nucleophil
Re-discussion on the influence of fluorine atoms. Fluorine atoms are extremely electronegative, and they are attached to the benzene ring, which can affect the electron cloud density of the benzene ring through induction and conjugation effects. Due to its strong electron-absorbing ability, the electron cloud density of the benzene ring decreases, especially in the ortho and para-positions. This change in electron cloud density affects the activity and regioselectivity of electrophilic substitution reactions on the benzene ring. Usually, electrophilic reagents tend to attack the intermediate position with relatively high electron cloud density.
As for ethoxy, it is a power supply subgroup, which can increase the electron cloud density of the benzene ring through conjugation effect, which is opposite to that of fluorine atoms. The electron cloud density of the benzene ring can increase, and the reactivity of the benzene ring to electrophilic reagents can be enhanced. When 2-ethoxy-4-fluorobromobenzene is used for electrophilic substitution reaction, the choice of the reaction check point is affected by the combined electronic effect of fluorine atom and ethoxy group.
And because of its ethoxy group, the ethoxy group can undergo hydrolysis reaction under acidic or basic conditions. In acidic medium, the ethoxy group gradually hydrolyzes to form phenolic compounds and alcohols. In conclusion, the chemical properties of 2-ethoxy-4-fluorobromobenzene are formed by the interaction of functional groups in its molecules. In the field of organic synthesis, various chemical reactions can be designed and realized according to their characteristics to prepare various organic compounds.
What are 2-Ethoxy-4-Fluorobromobenzene synthesis methods?
To prepare 2-ethoxy-4-fluorobromobenzene, the method of organic synthesis is often followed.
First, 4-fluorobromobenzene is used as the starting material. This compound contains bromine and fluorine, and ethoxy groups can be introduced into its phenolic hydroxyl group. Generally, 4-fluorobromobenzene is reacted with alkali first. For alkalis, such as sodium hydroxide, the phenolic hydroxyl group meets the base to form phenolic salts, and the activity of phenolic salts increases, which is conducive to nucleophilic substitution.
Then, add halogenated ethane, such as bromoethane. The oxygen of phenolic salts is nucleophilic, and the halogen atom of halogenated ethane is an electrophilic center. The two meet The oxygen of the phenate salt attacks the carbon of bromoethane, and the bromine ions leave, resulting in 2-ethoxy-4-fluorobromobenzene.
When reacting, the choice of solvent is also important. Aprotic polar solvents, such as N, N-dimethylformamide (DMF) or dimethyl sulfoxide (DMSO), can increase the solubility of ions and promote the reaction. Temperature also has an effect. Moderate heating can speed up the reaction, but if it is too high, it may cause side reactions.
In addition, phase transfer catalysts can also be used. Such as quaternary ammonium salts, which can transfer phenols from the aqueous phase to the organic phase, increase the contact of reactants, and improve the reaction efficiency.
Or it can be obtained from other fluorine, bromine, and ethoxy-containing raw materials through multi-step reactions. However, 4-fluorobromobenzene is the starting point, the steps are relatively simple, and the yield can be observed. It is a common way of synthesis.
2-Ethoxy-4-Fluorobromobenzene to pay attention to when storing and transporting
2-Ethoxy-4-fluorobromobenzene is an organic compound. When storing and transporting it, the following aspects should be paid attention to:
** Storage essentials **:
First, choose a cool, dry and well-ventilated place. Cover the compound or be sensitive to heat. If stored in a high temperature environment, it may cause chemical reactions or even cause decomposition. Therefore, it should be kept away from direct sunlight and close to heat sources to prevent high temperature from affecting its stability.
Second, it needs to be stored separately from oxidants, acids, bases, etc. Because of its chemical properties or cause violent reactions with these substances, such as oxidation-reduction reactions, acid-base neutralization reactions, etc., which in turn affect its quality and even cause safety accidents.
Third, the storage container must be tightly sealed. This can prevent the compound from volatilizing into the air, not only to avoid pollution to the environment, but also to prevent it from reacting with oxygen, moisture and other components in the air to ensure that its chemical properties are stable.
** Need for transportation **:
First, ensure that the packaging is intact before transportation. The packaging material should have good sealing and impact resistance, which can effectively resist bumps and collisions during transportation and prevent compound leakage.
Second, the temperature should be strictly controlled during transportation. Excessive temperature fluctuations should be avoided to prevent the compound from deteriorating due to temperature discomfort.
Third, transportation vehicles should be equipped with corresponding emergency treatment equipment and protective equipment. In the event of an accident such as leakage, treatment can be carried out in time to reduce the harm. And transportation personnel must be professionally trained to be familiar with the characteristics of the compound and emergency treatment methods to ensure safe transportation.