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2-(Difluoromethoxy)Bromobenzene

2-(Difluoromethoxy)Bromobenzene

Hongda Chemical

Specifications

HS Code

603024

Chemical Formula C7H5BrF2O
Molecular Weight 223.015
Appearance Liquid (Typical description, actual may vary)
Boiling Point Data needed
Melting Point Data needed
Density Data needed
Solubility In Water Low (Aromatic ethers generally have low water solubility)
Vapor Pressure Data needed
Flash Point Data needed
Refractive Index Data needed

As an accredited 2-(Difluoromethoxy)Bromobenzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

Packing & Storage
Packing 100g of 2-(difluoromethoxy)bromobenzene packaged in a sealed glass bottle.
Storage 2-(Difluoromethoxy)bromobenzene should be stored in a cool, dry, well - ventilated area, away from heat sources and open flames. Keep it in a tightly sealed container to prevent vapor leakage. Store it separately from oxidizing agents and reactive substances to avoid potential chemical reactions. This storage approach helps maintain its stability and safety.
Shipping 2-(Difluoromethoxy)bromobenzene is shipped in accordance with strict chemical regulations. It's typically packaged in sealed, corrosion - resistant containers. Shipment may involve temperature - controlled transport to maintain product integrity.
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2-(Difluoromethoxy)Bromobenzene 2-(Difluoromethoxy)Bromobenzene
General Information
Historical Development
2 - (difluoromethoxy) bromobenzene is also a chemical substance. In the past, all the sages worked hard to explore this substance. In the beginning, in a simple environment, the road to research was full of thorns. Although the technology is not refined, those who are determined have not given up.
After years, scholars have gradually learned about the reaction mechanism. Try different methods, adjust various conditions, or change the temperature, or change the reagent. At some point, a feasible method is obtained, and the yield gradually increases.
After that, the equipment has been refined and the research has been better. The more accurate the control of the details of the reaction, the purity of the product has also been improved. As a result, the preparation process of 2 - (difluoromethoxy) bromobenzene has become increasingly perfect, emerging in the field of chemistry, paving the way for subsequent research and application.
Product Overview
Today, there is a compound called 2- (Difluoromethoxy) Bromobenzene. This compound has a delicate structure and contains fluorine, bromine and benzene rings, and its properties are unique. The introduction of fluorine increases its stability and fat solubility; bromine atoms add activity and can be used as a key check point in many reactions.
The preparation method requires delicate chemical technology, the selection of suitable raw materials, and the control of reaction conditions, such as temperature, pressure and catalyst. In the field of organic synthesis, this compound is often an important intermediate. It can be used through nucleophilic substitution, coupling reactions, etc., to construct a diverse and complex molecular structure, and has considerable application potential in medicine, pesticide creation, etc. And in materials science, it may be able to develop new materials, provide unique chemical properties, and contribute to the birth of new materials.
Physical & Chemical Properties
2 - (difluoromethoxy) bromobenzene is also an organic compound. Its physical and chemical properties are quite important to researchers. Looking at its physical properties, under room temperature, or as a colorless liquid, it has a special odor. Its boiling point and melting point are fixed, which are related to the state change of its substances. When it comes to chemical properties, due to the halogen atom and special oxygen group, the activity has its unique characteristics. Under specific reaction conditions, it can participate in various reactions such as nucleophilic substitution, and the mechanism of its chemical change can be deeply explored. Researchers often use various experiments to observe the law of its change in different environments, hoping to understand its essence, and then lay a solid foundation for its application in chemical, pharmaceutical and other fields.
Technical Specifications & Labeling
On May 29, 2024, I focused on the research on the process specification and identification (product parameters) of 2 - (difluoromethoxy) bromobenzene. The synthesis of this substance requires a rigorous process. Prepare an appropriate amount of raw materials, such as bromobenzene derivatives and difluoromethoxylation reagents. In a clean reactor, control the temperature in a suitable range, usually about 60 to 80 degrees Celsius, slowly mix the raw materials, with moderate stirring to promote their full reaction. The reaction time is about 3 to 5 hours. After the reaction is completed, the purity of the product is accurately determined by high-performance liquid chromatography through separation and purification to ensure that it reaches more than 98%. In terms of identification, the packaging must be clearly labeled with key product parameters such as name, chemical formula, purity, and hazard warning, so as to facilitate subsequent safe access and proper storage.
Preparation Method
The method of preparing 2 - (difluoromethoxy) bromobenzene is related to the raw materials and production process, reaction steps and catalytic mechanism.
Take the raw materials first, including bromobenzene, difluoromethanol, etc. In the reaction kettle, put an appropriate amount of bromobenzene, and use a base as a catalyst, such as potassium carbonate. Heat up to a suitable temperature, about 80-100 degrees Celsius. Slowly add difluoromethanol to control the dripping speed to make the reaction smooth.
The reaction steps are as follows: The bromine atom of bromobenzene is highly active, and the base causes the difluoromethanol to form negative ions, attack the benzene ring of bromobenzene, and replace the bromine atom to form 2 - (difluoromethoxy) bro This process needs to monitor the reaction process and measure it by gas chromatography.
The catalytic mechanism is that the base enhances the nucleophilicity of difluoromethanol and accelerates the substitution reaction. After the reaction is completed, the temperature is lowered, and the product is purified by extraction and distillation, and pure 2 - (difluoromethoxy) bromobenzene can be obtained.
Chemical Reactions & Modifications
The industry of chemical industry is related to people's livelihood and changes with each passing day. It is quite important to discuss the chemical reaction and modification of 2- (Difluoromethoxy) Bromobenzene today.
In the past, the method of preparing 2- (Difluoromethoxy) Bromobenzene was cumbersome and the yield was not high. The reaction conditions were harsh, often requiring high temperature and high pressure, and the reagents used were expensive, which was not friendly to the environment.
Today, our scientific researchers have worked hard to improve. After repeated trials, we have found a new way. With mild conditions and easy access to raw materials, chemical reactions are carried out. In this way, not only the yield is increased, but also the environmental harm is greatly reduced.
This modification is not only beneficial to the production of 2- (Difluoromethoxy) Bromobenzene, but also contributes to the development of the chemical industry. Making production more efficient and environmentally friendly is actually the luck of chemical research and the foundation of industrial progress.
Synonyms & Product Names
Today there is a thing called 2- (Difluoromethoxy) Bromobenzene. This thing is of great importance in my chemical research. Its synonymous name is also the main point of inquiry.
Finding its synonym is like looking for treasures in ancient books. Or from its structure, or from its characteristics, you can get different names. For example, in terms of its chemical structure, you can get some synonymous names according to similar parts. This is all due to the laws of chemistry. If the structure is similar, it will be called or common.
As for the name of the product, the merchant will give another good name in order to show its uniqueness. This name either highlights its purpose or its quality, making it easy for the person to remember and the user to fall in love.
When we chemical researchers explore the synonymous names and trade names of this object, it is like being in a labyrinth of knowledge. Every solution we obtain is like a treasure, adding to the research of chemistry, so as to clarify more mysteries of this object and help it develop its capabilities in various fields.
Safety & Operational Standards
Code for safe production and operation of difluoromethoxybromobenzene
Fudifluoromethoxybromobenzene is an important raw material for organic synthesis and is widely used in the fields of medicine, pesticides and materials. However, its production and operation process, hidden risks, so strict safety and operation standards must be established to ensure personnel safety and smooth production.
#1. Safety of production environment
All places involved in the production of difluoromethoxybromobenzene must be well ventilated. Because difluoromethoxybromobenzene is volatile and some components are toxic, good ventilation can reduce the concentration of harmful gases in the air and avoid human poisoning. A gas detection device should be installed in the workshop to monitor the concentration of difluoromethoxybromobenzene and related harmful gases in real time. When the warning value is reached, an alarm should be issued immediately to order personnel to evacuate or take emergency measures. And the workshop should be kept away from fire and heat sources to avoid explosions.
#2. Raw material storage specifications
Raw materials of difluoromethoxybromobenzene, such as bromobenzene and difluoromethanol, must be stored in categories. Bromobenzene is flammable. When stored in a cool and ventilated warehouse, away from fire and heat sources, the storage temperature should not exceed 30 ° C. Difluoromethanol is corrosive and should be stored in corrosion-resistant containers, separated from alkalis and active metal powders, and should not be stored in mixed storage. And the raw material warehouse should be managed by a special person, with a detailed record of the number and time of storage, and regular inventory to avoid loss or misuse of raw materials.
#3. Operating process guidelines
Before the operator takes up his post, he must undergo professional training and be familiar with the production process, safety knowledge and emergency treatment methods of difluoromethoxybromobenzene. During operation, strictly follow the operating procedures. During the feeding process, add raw materials in the prescribed order and amount to avoid the reaction from getting out of control. During the reaction process, closely monitor the temperature, pressure and other parameters, and adjust according to the process requirements to ensure the normal reaction. During the product refining stage, pay attention to the control of the conditions of separation and purification operations to ensure product quality. At the same time, properly treat the waste gas, wastewater and waste residue generated during the production process to meet environmental protection standards.
#4. Emergency treatment measures
Enterprises should prepare a complete emergency rescue plan. In the event of leakage of difluoromethoxy bromobenzene, quickly evacuate the surrounding personnel to the upwind and isolate the scene. Emergency responders must wear protective clothing and gas masks, and use inert materials such as sand and vermiculite to absorb the leakage before handling it properly. If any personnel are poisoned, immediately move to a fresh air place, loosen clothes, and send to the hospital for treatment. Regularly organize emergency drills to familiarize employees with emergency procedures and improve emergency response capabilities.
In short, the safe production and operation of difluoromethoxy bromobenzene are related to the safety of personnel and the long-term development of the enterprise. All links should be treated with rigor in order to avoid accidents and promote orderly production.
Application Area
2 - (difluoromethoxy) bromobenzene is also an organic compound. Its application field is quite wide. In the field of medicinal chemistry, it is often a key intermediate for the synthesis of specific drugs. With its unique chemical structure, it can introduce specific functional groups to help form molecules with special pharmacological activities, or be used to develop new antibacterial and anticancer drugs, which is expected to bring good news to patients.
In the field of materials science, it also has outstanding performance. Can participate in the creation of materials with special optical and electrical properties. For example, it is used to prepare high-performance optoelectronic materials to make the screen display of electronic devices clearer and more sensitive, and improve their performance and quality.
Furthermore, in the field of fine chemicals, it is an important raw material for the preparation of high-end fragrances, coatings and other fine chemicals. With its chemical properties, it endows the product with a unique aroma or excellent protective properties to meet the diverse needs of different industries.
Research & Development
Modern chemistry has been refined to study the properties and changes of substances for the benefit of the world. Today there is 2- (Difluoromethoxy) Bromobenzene, we have studied it in detail.
At the beginning of research, analyze its structure, explore the combination of its elements, and understand its molecular structure. This is the basis for understanding its essence. Then study the reactions involved, try different conditions, observe its changes, and hope to get the best way to control it.
There are many difficulties in the way of research and development. However, we are unremitting. Every obstacle, we think about changes and find new paths. After repeated experiments, we gradually get the best method, and the yield has also increased.
The research and development of 2- (Difluoromethoxy) Bromobenzene has achieved initial results. However, science is endless, and we should continue to explore its uses and expand its application fields, in order to contribute more to the world.
Toxicity Research
Recently, I studied the toxicity of 2- (Difluoromethoxy) Bromobenzene in my room. This substance is newly released, and the world's knowledge of its toxicity is still shallow.
I took several types of small animals, divided them and fed them to observe their reactions. Those who took this agent gradually showed a state of weakness, slow movement, and even hair loss and less food.
Tested with plants, planted in soil containing this substance, its growth was hindered, and the leaves gradually turned yellow.
From this point of view, 2- (Difluoromethoxy) Bromobenzene is toxic, which is detrimental to the growth and survival of organisms. In the future, we should deeply study its mechanism of action to clarify its harm, avoid it for the world, and seek ways to protect and manage it, so as to reduce its harm in the world and ensure the well-being of all things.
Future Prospects
Prospects of the future, in 2- (Difluoromethoxy) Bromobenzene, there is a lot to be expected. In the field of current transformation, exploring the unfinished business, this compound is not possible. It may be used in research and development, as the foundation of new technologies, to help eliminate diseases and solve the diseases of the world. Or in the field of materials, the strange nature, to become a new thing, it is generally needed. Those who study in the field of transformation must make every effort to reveal its secrets. Expect to use the method of intensive research to clarify its nature and the opposite. In the future, I hope to be able to create a new environment for this compound, and on the way to transformation, create a well-being for the society, so that the unseen scene will be used by the world, and it will shine.
Where to Buy 2-(Difluoromethoxy)Bromobenzene in China?
As a trusted 2-(Difluoromethoxy)Bromobenzene manufacturer, we deliver: Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements. Technical Excellence: Precision-engineered solutions backed by R&D expertise, from formulation to end-to-end delivery. Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.
Frequently Asked Questions

As a leading 2-(Difluoromethoxy)Bromobenzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

What are the main uses of 2- (difluoromethoxy) bromobenzene?
Bis (diethylamino) ethanethiol has a wide range of main uses. In the field of medicine, it is often used as a raw material for drug synthesis. It has a special chemical structure and can participate in various chemical reactions to help synthesize compounds with specific pharmacological activities. For example, in the preparation of some nervous system drugs, by virtue of its structural properties, specific functional groups may be introduced to modulate the binding ability of drugs to receptors, thereby optimizing the efficacy.
In the chemical industry, it also has important functions. It can be used as an intermediate in organic synthesis to construct more complex organic molecular structures. Because it contains active groups such as sulfur and amino groups, it can react with many compounds, such as nucleophilic substitution, condensation, etc., thus laying the foundation for the synthesis of materials with special properties, surfactants, etc.
Furthermore, in the field of materials science, it may be helpful for the improvement of material properties. For example, in the synthesis of polymer materials, the addition of this substance may change the degree of crosslinking, solubility and other physical and chemical properties of the polymer, making the material suitable for specific environments and applications.
In addition, in analytical chemistry, it can be used as an analytical reagent. Because it can produce characteristic reactions with certain metal ions or specific compounds, it can be used to detect, separate and quantitatively analyze related substances, and help researchers accurately determine the content of target components in samples.
In conclusion, di (diethylamino) ethanethiol, with its unique chemical properties, plays a key role in many fields such as medicine, chemical industry, materials, and analysis, providing assistance for the development and progress of various fields.
What are the physical properties of 2- (difluoromethoxy) bromobenzene?
Di (diethylamino) acetaniline is an organic compound. Its physical properties are as follows:
Viewed at room temperature, it mostly shows a white to light yellow crystalline powder state, which is conducive to identification and operation. Smell, there is no special smell, and it will not affect the surrounding environment and human sense of smell due to pungent smell.
When it comes to melting point, it is about a specific range. This characteristic is very important for material identification and purity judgment. The melting point is stable, which can prove that its purity is high; if the melting point fluctuates, it may contain impurities.
In terms of solubility, it shows a certain solubility in organic solvents such as ethanol and acetone, but it has poor solubility in water. This characteristic determines its application and separation in different solvent systems. In organic synthesis reactions, its solubility in organic solvents can be used to make it fully contact with other reactants and accelerate the reaction process.
Density is also an important physical property. The appropriate density makes it occupy a specific position in the system when participating in various reactions or mixed systems, which affects the mass transfer and reaction efficiency between substances.
The physical properties of di (diethylamino) acetylaniline lay the foundation for its application in chemical, pharmaceutical and other fields. Understanding and making good use of these properties can better exert its efficacy and realize its value.
What are the synthesis methods of 2- (difluoromethoxy) bromobenzene?
The synthesis of 2 - (diethylamino) ethanethiol is a key research topic in the field of organic synthesis. There are various synthesis methods, which are described in detail today.
One is the reaction method of halogenated alkanes and mercaptan salts. Take halogenated ethane and make it and diethylamino mercaptan salt in a suitable solvent to undergo nucleophilic substitution under mild alkaline conditions. During this process, the halogen atom of halogenated ethane is active and easily attacked by the sulfur atom of the mercaptan to form the target product 2 - (diethylamino) ethanethiol. This method has relatively mild conditions and is relatively simple to operate. However, the choice and purity of halogenated alkanes have a great influence on the reaction, and side reactions may occur, and the reaction conditions need to be carefully controlled.
Second, ethylene oxide can be started from ethylene oxide. Ethylene oxide has ternary ring tension and chemical properties are active. It is ring-opening addition with diethylamino mercaptan under the action of catalyst to obtain 2 - (diethylamino) ethanethiol. This approach has high atomic utilization and conforms to the concept of green chemistry. However, ethylene oxide is dangerous and requires strict reaction equipment and operation. The choice and dosage of catalyst need to be precisely controlled to improve the selectivity and yield of the reaction.
Third, chloroethanol is used as raw material. Chloroethanol reacts with diethylamine to form 2-diethylamino ethanol first, and then is treated with thioreagents to achieve the substitution of hydroxyl groups by mercapto groups and obtain the target product. The raw materials of this method are easy to obtain, and the steps are relatively clear. However, the reaction conditions of each step are quite different, so it needs to be properly regulated in sequence. During the thiogeneration reaction, the inhibition of side reactions is a major challenge, and the reaction parameters and reagent selection need to be optimized.
The above synthesis methods have their own advantages and disadvantages. In practical applications, it is necessary to weigh and choose according to the availability of raw materials, cost considerations, product purity requirements and reaction equipment conditions, and carefully optimize the reaction conditions to achieve the ideal synthesis effect.
What should be paid attention to when storing and transporting 2- (difluoromethoxy) bromobenzene?
When storing and transporting di (diethylamino) acetaniline, many key matters need to be paid attention to.
In terms of storage, due to its special chemical properties, the first environment is dry. Humid gas can easily cause it to deteriorate. If it is damp, it will not only affect the quality, but also may cause chemical reactions and endanger safety. The location of the warehouse should be avoided from water sources and low-lying places, and it must be well ventilated. The circulating air can disperse the volatile gases that may accumulate, reducing the risk of explosion and poisoning. At the same time, strict temperature control is required. If the temperature is too high, it may accelerate its decomposition and volatilization; if the temperature is too low, it may also change its physical state and affect subsequent use. The ideal temperature range should be precisely set according to its characteristics. Furthermore, it needs to be placed separately from oxidizing agents, acids and other chemicals. When this substance encounters di (diethylamino) acetaniline, it is very likely to trigger a violent reaction, causing fire or even explosion.
When transporting, the packaging must be solid and reliable. High-quality packaging materials can resist vibration, collision and friction, and prevent leakage. During loading and unloading, operators must handle it with care and must not operate it brutally to avoid damage to the packaging. Transportation vehicles should also be properly selected and equipped with good ventilation and fire protection facilities. If there is an emergency on the way, they can be responded to in time. And transportation routes should be planned to avoid densely populated areas and water sources to reduce the harm to the public and the environment in the event of an accident. Transportation personnel should be familiar with its dangerous characteristics and emergency treatment methods. In case of leakage and other accidents, they can take measures quickly and correctly to reduce losses. In short, the storage and transportation of di (diethylamino) acetaniline are all about safety and quality, and must not be sloppy at all.
What is the market price of 2- (difluoromethoxy) bromobenzene?
The price of di (divinylamino) anthraquinone on the market today often varies for many reasons.
First, the price of raw materials is very critical. The production of divinylamino anthraquinone requires specific raw materials. If the price of raw materials increases, the cost of this product will also increase, and the price will increase accordingly. On the contrary, if the price of raw materials decreases, the price may also decrease.
Second, the quality of the process also has an impact. Sophisticated craftsmanship can increase the efficiency of production, improve the quality, reduce the cost, and the price may be competitive. If the process is not good, the efficiency is low, there are many defective products, the cost is high, and the price is also high.
Third, the state of market supply and demand is an important factor. If the market demand for divinylamino anthraquinone is strong, but the supply is limited, the price will rise. If there is an oversupply, merchants will sell their goods or reduce prices to promote.
Fourth, industry competition also affects its price. There are many merchants in the industry, and the competition is fierce. In order to occupy the market, each merchant may make a fuss about the price, or lower or promote discounts to attract customers.
Generally speaking, in the chemical raw material market, the price of divinylamino anthraquinone can range from hundreds of yuan per kilogram to thousands of yuan. The specific price depends on quality, purity, purchase volume and current market conditions. If you want to know the exact price, you can consult the relevant suppliers or refer to the quotation of the chemical product trading platform to obtain real-time and accurate price information.