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2-(Chloromethyl)-4-Fluoro-1-(Trifluoromethyl)Benzene

2-(Chloromethyl)-4-Fluoro-1-(Trifluoromethyl)Benzene

Hongda Chemical

    Specifications

    HS Code

    608790

    Chemical Formula C8H5ClF4
    Molar Mass 214.57 g/mol
    Appearance likely a colorless to pale - colored liquid
    Boiling Point data may vary, needs experimental determination
    Melting Point data may vary, needs experimental determination
    Density data may vary, needs experimental determination
    Solubility In Water likely low, as it is an organic halide
    Solubility In Organic Solvents soluble in common organic solvents like dichloromethane, toluene
    Vapor Pressure data may vary, needs experimental determination
    Flash Point data may vary, needs experimental determination

    As an accredited 2-(Chloromethyl)-4-Fluoro-1-(Trifluoromethyl)Benzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing 100 - gram bottle packaging for 2-(chloromethyl)-4 - fluoro - 1-(trifluoromethyl)benzene.
    Storage 2-(Chloromethyl)-4-fluoro-1-(trifluoromethyl)benzene should be stored in a cool, well - ventilated area, away from heat sources and open flames. Keep it in a tightly - sealed container to prevent vapor leakage. Store it separately from oxidizing agents and reactive chemicals to avoid potential reactions. Ensure storage conditions are dry to prevent hydrolysis.
    Shipping 2-(Chloromethyl)-4-fluoro-1-(trifluoromethyl)benzene is shipped in accordance with chemical transport regulations. Packed in appropriate containers, it's transported by approved carriers, ensuring safety during transit.
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    2-(Chloromethyl)-4-Fluoro-1-(Trifluoromethyl)Benzene 2-(Chloromethyl)-4-Fluoro-1-(Trifluoromethyl)Benzene
    General Information
    Historical Development
    Fu2- (chloromethyl) -4-fluoro-1- (trifluoromethyl) benzene is also an organic compound. At the outset, chemists studied the laws of physical properties and reactions, and expanded the field of chemistry. At first, the understanding was still shallow, and the synthesis method was also difficult.
    However, Zhu Xian has been unremitting for a long time, exploring the structure of molecules and studying the mechanism of reactions. Gradually, he has obtained the best method to make the synthesis of this substance stable and efficient. From the difficult creation in the past to the wide use in organic synthesis, material preparation and other fields today, it all depends on the efforts of scholars of all dynasties. Its development process is one of the spots in the evolution of chemistry, witnessing the courage of human beings to move forward in science, and unremitting pursuit of innovation to achieve today's grand scene.
    Product Overview
    Today there is a product called 2- (chloromethyl) -4-fluoro-1- (trifluoromethyl) benzene. Its shape is colorless and has a special smell. This is the key raw material for organic synthesis, and it is widely used in medicine, pesticides and other fields.
    The preparation method mostly starts with specific benzene derivatives and is formed by several steps of chloromethylation and fluorination. During the reaction, it is necessary to finely adjust the temperature, reagent dosage and reaction time to obtain high-purity products.
    Looking at its properties, it is chemically active due to the presence of groups such as fluorine and chloromethyl. In organic reactions, it is often used as an electrophilic reagent and reacts with many nucleophiles to generate a variety of compounds.
    Although this substance is widely used, safety should also be paid attention to when preparing and using it. Because it contains halogen atoms, it may be toxic and corrosive to a certain extent. When operating, follow the norms to ensure personal and environmental safety.
    Physical & Chemical Properties
    2 - (chloromethyl) -4 -fluoro-1- (trifluoromethyl) benzene is also an organic compound. Its physical and chemical properties are quite important to scholars. This compound is at room temperature, or in a liquid state, with a special odor. The genera of its boiling point and melting point are related to its physical state changes and affect practical applications.
    From the perspective of chemical properties, its chemical activity is unique because it contains groups such as chloromethyl, fluorine and trifluoromethyl. Chloromethyl is prone to substitution reactions, fluorine atoms change the distribution of molecular electron clouds, and trifluoromethyl enhances the stability and hydrophobicity of compounds. The study of its physical and chemical properties is of great significance in the fields of organic synthesis, materials science, etc., which can help to expand new reaction paths, develop new functional materials, and promote the progress of chemistry.
    Technical Specifications & Labeling
    2 - (chloromethyl) -4 -fluoro-1 - (trifluoromethyl) benzene, the process specification and identification (product parameters) of this compound are related to many important aspects. The process specification needs to strictly follow the specific process, from the selection of raw materials, which must be of the highest quality and meet the purity standards, to the reaction conditions, temperature, pressure and other parameters need to be precisely controlled to ensure the quality of the product.
    In terms of identification, product parameters should be clearly marked, such as chemical structure, which needs to be accurately illustrated to show its atomic connection method; purity index, when the specific value is clear, to prove the quality. In this way, this product can be used in industrial production and scientific research applications to achieve the best effect, and it is convenient for all users to clarify its characteristics and usage specifications, so as to achieve the purpose of safety and efficiency.
    Preparation Method
    To prepare 2 - (chloromethyl) - 4 - fluoro - 1 - (trifluoromethyl) benzene, the raw materials and production process are very critical. Take fluorobenzene and trifluoromethylation reagent, mix them in a specific ratio, and under the action of suitable temperature and catalyst, through nucleophilic substitution reaction, the benzene series containing trifluoromethyl is initially obtained.
    Then, the product is co-placed in a reaction kettle with chloromethylation reagent, and the reaction conditions are adjusted according to a certain process. The Friedel-Crafts reaction mechanism is used to successfully connect the chloromethyl to the corresponding position of the benzene ring. During the reaction, factors such as temperature, pressure and reaction time are strictly controlled, and the process is closely monitored to ensure a smooth reaction. In this way, the target product 2 - (chloromethyl) - 4 - fluoro - 1 - (trifluoromethyl) benzene can be obtained through multi-step fine operation.
    Chemical Reactions & Modifications
    To taste the wonders of chemical industry, it is related to the change of substances, and the reaction and modification are particularly important. Today there is 2- (Chloromethyl) -4-Fluoro-1- (Trifluoromethyl) Benzene. In the field of chemistry, its reaction and modification are worth exploring.
    To understand its reaction, consider its structure. This compound contains chloromethyl, fluorine and trifluoromethyl, and each group interacts to affect its chemical activity. Chloromethyl is active and easy to involve nucleophilic substitution, which is a key check point for the reaction. Fluorine atoms are electronegative, which can affect molecular polarity and reaction selectivity. Trifluoromethyl changes the electron cloud distribution of benzene ring with strong electron absorption.
    As for modification, chemical means can be used to change its structure and adjust its properties. For example, with specific reagents, chloromethyl can be replaced, new groups can be introduced to improve its solubility and stability. Or by the characteristics of fluorine, optimize its affinity with other substances. Through this reaction and modification, it may be able to expand its uses and develop its unique capabilities in the fields of medicine, materials and other fields, adding to the progress of chemistry.
    Synonyms & Product Names
    2 - (chloromethyl) -4 -fluoromethyl-1 - (trifluoromethyl) benzene is very important in the field of chemical research. Its synonyms and trade names are like many titles of the same thing in ancient books. Although the expressions are different, they actually refer to the same thing.
    In the past, when the Fang family explored this chemical substance, different names were born due to different perspectives and uses. The synonyms are determined from the perspectives of their chemical structure and properties to highlight their characteristics. For trade names, more factors such as market and application are considered to facilitate identification and promotion.
    This 2- (chloromethyl) -4-fluoro-1- (trifluoromethyl) benzene may have synonyms such as [list possible synonyms 1], [list possible synonyms 2], or [list possible synonyms 1], [list possible trade names 2], etc. All names revolve around this thing, just like the stars and the moon. Although the names are numerous, the core is this unique chemical substance, which plays an indispensable role in the process of chemical research and development and production.
    Safety & Operational Standards
    Specifications for the safety and operation of 2- (chloromethyl) -4-fluoro-1- (trifluoromethyl) benzene
    Fu2- (chloromethyl) -4-fluoro-1- (trifluoromethyl) benzene is an important substance in chemical research. In its experimental operation and use, safety and norms are the top priority.
    As far as storage is concerned, it should be placed in a cool, dry and well-ventilated place. Avoid open flames and hot topics to prevent accidents. This substance has certain chemical activity. In case of heat or ignition, it may react violently and endanger safety. It should be stored separately from oxidizing agents and bases, and should not be mixed to prevent dangerous interaction.
    When operating, the experimenter must wear appropriate protective equipment. Wear protective clothing, goggles and gloves to protect themselves from harm. Because the substance may be irritating and corrosive to the skin and eyes. The operating environment must be well ventilated. If conditions permit, it is appropriate to work in a fume hood to disperse possible harmful gases and ensure the safety of the experimenter's breathing.
    When taking it, the action should be stable and accurate, and the operation should be carried out according to the method of accurate measurement. Do not take it in excess, resulting in waste and danger. If it is accidentally spilled, emergency response should be initiated immediately. Evacuate irrelevant personnel quickly first, and then clean up according to the corresponding procedures. A small amount of spill can be absorbed by inert materials such as sand and vermiculite; if the amount is large, a professional cleaning team is required to prevent the spread of pollution.
    Furthermore, the experimental records should not be underestimated. The operation steps, dosage, reaction conditions, etc. should be recorded in detail. This not only helps to repeat the experiment and analyze the results, but also provides an important basis for subsequent security evaluation.
    In short, in the research and use of 2- (chloromethyl) -4-fluoro-1- (trifluoromethyl) benzene, strict adherence to safety and operating standards can ensure the smooth operation of the experiment and protect the safety of personnel and the environment.
    Application Area
    Today there is a product called 2- (Chloromethyl) -4-Fluoro-1- (Trifluoromethyl) Benzene. This product has its uses in many fields.
    In medicine, it may be a key raw material for pharmaceuticals. It can help doctors make good medicines to cure diseases and save lives from diseases.
    In the field of chemical industry, it can also play a wonderful role. Or it can be used to synthesize various special materials, making the materials unique and suitable for special places.
    In the process of scientific research, it is often the key to exploration. Scientists use its characteristics to explore unknown principles and expand the boundaries of knowledge. In short, 2- (Chloromethyl) -4-Fluoro-1- (Trifluoromethyl) Benzene is of great value in the application fields of medicine, chemical industry and scientific research.
    Research & Development
    Recently, we have studied this 2- (chloromethyl) -4-fluoro-1- (trifluoromethyl) benzene and deeply felt its significance. This compound has unique properties and may have broad prospects in various fields of chemical industry.
    We have carefully observed its reaction mechanism and investigated the changes under different conditions after many experiments. Factors such as temperature and catalyst dosage have a great impact on the product.
    The initial attempt, the results were not as expected. However, we were not discouraged and repeatedly adjusted the parameters. Finally, the optimization method was obtained, and the purity and yield of the product were significantly improved.
    Looking to the future, we hope to use this as a basis to further expand. Work with all parties to promote the application of this research result, realize its greater value, and contribute to the development of chemical industry, promoting progress in this field.
    Toxicity Research
    Study on Toxicity of 2- (Chloromethyl) -4-Fluoro-1- (Trifluoromethyl) Benzene
    Taste of chemical substances, their unpredictable nature, related to people's livelihood and health, must be observed. Now focusing on 2- (Chloromethyl) -4-fluoro-1- (trifluoromethyl) benzene, this substance may have its uses in the chemical industry, but the study of toxicity is crucial.
    Study from ancient methods, the first to observe its impact on organisms. Or enter the animal body to observe its physiological changes. If applied to mice, observe their diet, movement, and organs. See their eating less and less, slow movement, and abnormal organ color and texture. This is a sign of initial toxicity.
    Also explore its harm to the environment. Between water and soil, or cause imbalance of microbial communities, vegetation growth is blocked. And the stability of this thing or strong, long-term environment, accumulated over the years, the legacy of endless. It is based on toxicity research, in order to ensure the harmony of all things, it is urgent. It is necessary to study its nature in detail, in order to avoid harm and profit, so that the chemical industry can benefit the world without harm.
    Future Prospects
    The vision of the future, in terms of chemical things, is especially heavy on 2- (Chloromethyl) -4-Fluoro-1- (Trifluoromethyl) Benzene. Its characteristics are special, and its use is difficult. In the field of knowledge, it can be the foundation of the system, assist in research and development, and solve the problem of disease; in the field of materials, it can be synthesized into strange materials, and its effectiveness can be increased. We study its principles, make good use of its properties, and hope to use new methods to expand the world of its use. So that this product can be used in the future, the steps of the world, the well-being of people, and the best of its ability, with the expectations of the world, into an extraordinary world, and create a Huang Realm.
    Where to Buy 2-(Chloromethyl)-4-Fluoro-1-(Trifluoromethyl)Benzene in China?
    As a trusted 2-(Chloromethyl)-4-Fluoro-1-(Trifluoromethyl)Benzene manufacturer, we deliver: Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements. Technical Excellence: Precision-engineered solutions backed by R&D expertise, from formulation to end-to-end delivery. Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.
    Frequently Asked Questions

    As a leading 2-(Chloromethyl)-4-Fluoro-1-(Trifluoromethyl)Benzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

    What are the main uses of 2- (Chloromethyl) -4-Fluoro-1- (Trifluoromethyl) Benzene?
    2-%28Chloromethyl%29-4-Fluoro-1-%28Trifluoromethyl%29Benzene, the Chinese name is 2 - (chloromethyl) -4 - fluoro - 1 - (trifluoromethyl) benzene, the main purpose of this compound is.
    First, in the field of synthesis, it can be used as an important medium. Because its molecules contain chloromethyl, fluorine atoms and trifluoromethyl isofunctionals, it has high chemical activity. With its starting materials, such as substitution of antibodies, other functionalities can be used to replace chloromethyl, and a series of complex compounds can be synthesized. For example, containing nitrogen, oxygen and other nuclear antibodies, can build new carbon atoms, and derive many compounds with specific biological activities or material properties.
    Second, in terms of research, this compound also has a high value.
    Molecules often need to introduce specific functionalities to enhance efficiency and improve the ability of substitution. 2 - (chloromethyl) -4 -fluoro-1 - (trifluoromethyl) benzene can be used as a molecular skeleton. For example, fluorine-containing and trifluoromethyl compounds are often well fat-soluble in biology, which is beneficial for transcellular membrane development and increases the effectiveness of the target, so it may become an important precursor for new research.
    Third, it is also useful in the field of materials science. Because of its special functionalities, it can be used as a raw material for the synthesis of functional materials. For example, polymerization can be introduced into polymer materials to give them special properties, such as corrosion resistance and weather resistance. The synthesized materials can be used in materials, plastics, etc., to improve the material compatibility.
    What are the physical properties of 2- (Chloromethyl) -4-Fluoro-1- (Trifluoromethyl) Benzene?
    2 - (chloromethyl) -4 -fluoromethyl-1 - (trifluoromethyl) benzene, also an organic compound. Its physical properties are quite important, and it is widely used in chemical industry.
    Looking at its properties, at room temperature, this substance is mostly a colorless to slightly yellow transparent liquid. If placed under the light, it can be seen that it has a bright light, like a mirror reflection. Its smell is also specific, pungent and pungent, and the smell is frowning. This smell can be identified.
    As for the boiling point, it is about a certain temperature, and it varies slightly due to the influence of surrounding air pressure and other conditions. Under normal air pressure, its boiling point can cause the substance to gradually transform from liquid to gaseous and rise in the air. The melting point is also fixed. At a certain low temperature, the liquid gradually condenses into a solid, and the shape changes from flow to firm.
    Furthermore, its density is also an important physical characteristic. Compared with water, it is lighter or heavier, which is related to its distribution in the mixed system. And because of its molecular structure, its solubility is also characteristic. It is miscible in some organic solvents such as alcohols and ethers, but it is insoluble in water. If the two meet, such as oil floating in water, the boundary is clear.
    Its volatility cannot be ignored either. In the environment of normal temperature exposure, the molecules of this substance gradually escape in the air, causing its amount to gradually decrease. Therefore, when storing, it must be kept in a tight container to prevent its escape. These kinds of physical properties are all carefully observed by chemical workers, and they are used to do good things, or to make things, or to analyze substances.
    What are the synthesis methods of 2- (Chloromethyl) -4-Fluoro-1- (Trifluoromethyl) Benzene
    To prepare 2 - (chloromethyl) -4 -fluoro-1- (trifluoromethyl) benzene, common synthesis methods are as follows:
    First, the benzene derivative containing the corresponding substituent can be started, and chloromethyl can be introduced by halogenation reaction. For example, select a suitable benzene raw material with a protective group, first activate a specific position, so that the check point is easier to occur electrophilic substitution reaction. Then, use chloromethylation reagents, such as chloromethyl methyl ether, etc., in the presence of a suitable catalyst, such as anhydrous zinc chloride, in a suitable solvent, such as dichloromethane, etc., to control the reaction temperature and time to achieve the introduction of chloromethyl. In this process, it is necessary to pay attention to the rational use of protective groups to avoid other unnecessary reactions and ensure the accurate introduction of chloromethyl into the target position.
    Second, the strategy of gradually constructing the benzene ring can be used. First, a suitable small molecule compound is used as the starting material, and through a series of reactions, such as nucleophilic substitution, condensation, etc., the benzene ring skeleton is gradually built, and fluorine atoms, trifluoromethyl and other substituents are introduced at the same time. When building the benzene ring skeleton, classic reactions such as Foucault reaction can be selected to realize the construction of the benzene ring and the connection of the substituent. After the benzene ring skeleton is formed, chloromethyl is introduced at the appropriate position. This step also requires attention to the precise control of the reaction conditions to prevent the
    Third, the reaction path of transition metal catalysis can also be used. Halogenated aromatics containing fluorine and trifluoromethyl are used as substrates, and under the action of transition metal catalysts, such as palladium catalysts, the coupling reaction occurs with chloromethyl-containing reagents. The reaction needs to be carried out in an appropriate ligand, base and solvent system. By optimizing the reaction parameters, such as temperature, catalyst dosage, etc., the selectivity and yield of the reaction can be improved. This method uses the high efficiency and selectivity of transition metal catalysis to synthesize the target product more accurately.
    The above methods have their own advantages and disadvantages. In actual synthesis, many factors such as the availability of raw materials, cost, difficulty in controlling reaction conditions, and the purity requirements of the product should be comprehensively considered to select the most suitable synthesis route.
    2- (Chloromethyl) -4-Fluoro-1- (Trifluoromethyl) Benzene What are the precautions in storage and transportation?
    For 2 - (chloromethyl) -4 - fluoro-1 - (trifluoromethyl) benzene, many matters need to be paid attention to during storage and transportation.
    This substance has certain chemical activity. When stored, the first environment is dry. Moisture can easily lead to its chemical reaction and cause quality deterioration. Therefore, it should be placed in a dry and well-ventilated place, away from water sources and moisture, such as in a high place and away from water pipes and sinks.
    Temperature is also critical. It should be controlled within an appropriate range to avoid high temperature and severe cold. High temperature can cause its volatilization to intensify, or cause reactions such as decomposition; severe cold may cause changes in physical properties, affecting its use. Usually, room temperature and stable conditions are appropriate.
    During transportation, the packaging must be tight. To prevent leakage, it may be harmful to the environment and human body. The packaging materials used must be resistant to chemical corrosion and can withstand certain external impacts, such as special chemical packaging drums, and reinforced protection.
    Furthermore, this substance may have certain toxicity and irritation. Those who store and transport must wear suitable protective equipment, such as gloves, protective clothing and masks, to avoid contact and inhalation. And the workplace should have good ventilation facilities to disperse harmful gases in time.
    Because it is a chemical, storage and transportation must comply with relevant regulations and standards. Complete documentation, including source, quantity, whereabouts, etc., for inspection, to ensure process compliance and safety.
    What is the market price range for 2- (Chloromethyl) -4-Fluoro-1- (Trifluoromethyl) Benzene?
    "Market price range of 2 - (chloromethyl) - 4 - fluoro - 1 - (trifluoromethyl) benzene". However, the price of this product is difficult to determine, and it is affected by many factors.
    First of all, the production process is complicated and simple. If the preparation method is exquisite and complicated, the required raw materials are precious and the process is cumbersome, such as alchemy, which requires many rare medicines and fire control, the cost will be high, and the price will be high.
    Furthermore, the trend of market supply and demand is also the key. If there are many people who want it, it will be used in urgent fields such as medicine and materials, but there are few products, and the supply is in short supply. If it is a rare treasure in the world, the price will rise. On the contrary, if the supply exceeds the demand and the stock of goods is like a mountain, the price will fall.
    Again, the quality is good or bad, and the impact is shallow. Those with high purity and few impurities are like fine gold and jade, with high value; those with poor quality will be inferior in price.
    There are also regional differences, which cannot be ignored. In four places, the products are different, and the transportation is also different. For those produced nearby, the freight is saved, and the price may be slightly lower; for those transported from a distance, the freight is high, and the price may be slightly higher.
    As for the exact price range, it is difficult to say. Or explore the market and consult merchants to get a more accurate number. If you want to buy it, you must inquire from many parties and weigh the quality and price before you can get it.