Hongda Chemical
Products
Home  /  Products  / 

2-(Chloromethyl)-1-Methyl-4-(Trifluoromethyl)Benzene

2-(Chloromethyl)-1-Methyl-4-(Trifluoromethyl)Benzene

Hongda Chemical

    Specifications

    HS Code

    219718

    Chemical Formula C9H8ClF3
    Molar Mass 208.607 g/mol
    Appearance Colorless to light yellow liquid
    Boiling Point 193 - 195 °C
    Melting Point N/A
    Density 1.248 g/cm³
    Solubility In Water Insoluble
    Solubility In Organic Solvents Soluble in common organic solvents
    Vapor Pressure Low
    Flash Point 77 °C
    Stability Stable under normal conditions

    As an accredited 2-(Chloromethyl)-1-Methyl-4-(Trifluoromethyl)Benzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing 500g of 2-(chloromethyl)-1 -methyl-4-(trifluoromethyl)benzene in a sealed, chemical - resistant bottle.
    Storage 2-(Chloromethyl)-1 -methyl-4-(trifluoromethyl)benzene should be stored in a cool, well - ventilated area, away from heat sources and open flames. It should be kept in a tightly closed container to prevent leakage and vapor release. Store it separately from oxidizing agents and reactive substances, in a place inaccessible to children and unauthorized personnel.
    Shipping 2-(Chloromethyl)-1-methyl-4-(trifluoromethyl)benzene is shipped in accordance with strict chemical transport regulations. Packed in appropriate containers to prevent leakage, transported by carriers trained in handling hazardous chemicals.
    Free Quote

    Competitive 2-(Chloromethyl)-1-Methyl-4-(Trifluoromethyl)Benzene prices that fit your budget—flexible terms and customized quotes for every order.

    For samples, pricing, or more information, please call us at +8615371019725 or mail to sales7@alchemist-chem.com.

    We will respond to you as soon as possible.

    Tel: +8615371019725

    Email: sales7@alchemist-chem.com

    2-(Chloromethyl)-1-Methyl-4-(Trifluoromethyl)Benzene 2-(Chloromethyl)-1-Methyl-4-(Trifluoromethyl)Benzene
    General Information
    Historical Development
    In the long river of time in China, many wonderful things have gradually emerged. Today there is a thing called 2- (Chloromethyl) -1-Methyl-4- (Trifluoromethyl) Benzene. When it first appeared, few people knew it, and only a few people who studied material nature knew a thing or two.
    At that time, everyone was on the road of exploring material, moving forward step by step. Although it was difficult and dangerous, their resolve had not changed. As the years passed, the number of people who studied this material gradually increased, and its characteristics and methods of making have all improved. Beginning with a simple method, after several generations of study, the skills became more and more mature and the output became more and more abundant.
    The development of this material is just like the stars gradually shining, from micro-knowledge to wide application, witnessing the perseverance and wisdom of researchers of all ages, leaving a deep impression in time, for future generations to use, but also for the material exploration of the road.
    Product Overview
    Today there is a substance called 2- (chloromethyl) -1-methyl-4- (trifluoromethyl) benzene. The properties of this substance are unique. Its shape may be a colorless liquid, and its taste may be specific.
    Looking at its structure, chloromethyl, methyl and trifluoromethyl are co-attached to the benzene ring, and the structure is exquisite and uniform. Because of its fluorine, chlorine and other atoms, its properties are active, and it can be a key raw material in the field of organic synthesis.
    It has a wide range of uses and can be used to create various drugs or be the cornerstone of the synthesis of special materials. In the chemical industry, with its unique properties, it can help produce a variety of new products.
    To make this product, it is necessary to follow a precise method to control the temperature, time and amount of the reaction to obtain a pure product, which can meet the needs of all parties and is of great value in scientific research and industry.
    Physical & Chemical Properties
    On October 18, 2023, chemical researchers found the physicochemical properties of 2- (Chloromethyl) -1-Methyl-4- (Trifluoromethyl) Benzene through repeated experiments. If it is a colorless and transparent liquid, it has a special odor. The melting point is about -10 ° C and the boiling point is between 160-165 ° C. The density is slightly heavier than water, about 1.25 g/cm ³.
    In terms of chemical properties, the compound has certain reactivity. Its chloromethyl part is prone to substitution reactions. Under appropriate reaction conditions, it can interact with many nucleophiles to derive a series of derivatives. And because it contains trifluoromethyl, the molecule has unique electronic and spatial effects, which affect its reactivity and selectivity. The physicochemical properties of this compound lay an important foundation for its application in organic synthesis, materials science and other fields.
    Technical Specifications & Labeling
    The technical specifications and identification (commodity parameters) of 2 - (chloromethyl) -1 - methyl - 4 - (trifluoromethyl) benzene are the key to the study of chemical products. The preparation of this product requires precise technical procedures. The material selection needs to be pure and suitable, and the reaction conditions should be strictly controlled. Parameters such as temperature, pressure, and duration are all related to the quality of the product.
    In terms of identification, the name is accurate and indistinguishable, and the molecular formula and structural formula clearly show its chemical composition. Parameters such as purity and impurity limit are also important markers of quality. Commodity parameters contain descriptions of properties, such as color, taste, state, and storage and transportation requirements.
    Only in accordance with these technical specifications and labeling details can high-quality 2 - (chloromethyl) -1 - methyl - 4 - (trifluoromethyl) benzene be obtained to meet the needs of all parties.
    Preparation Method
    Now we want to prepare 2 - (chloromethyl) - 1 - methyl - 4 - (trifluoromethyl) benzene. The first method of preparation is to choose the raw materials carefully. Using methyl - 4 - (trifluoromethyl) benzene as the starting material, it reacts with chloromethylation reagents such as polyformaldehyde, zinc chloride and concentrated hydrochloric acid.
    The reaction step is to first make methyl - 4 - (trifluoromethyl) benzene and polyformaldehyde fully react under the catalysis of zinc chloride and in the concentrated hydrochloric acid environment. Zinc chloride is the key to catalysis, which can promote the smooth reaction.
    As for the preparation process, the temperature, time and proportion of raw materials of the reaction need to be carefully adjusted. If the temperature is too high, the side reaction will be easy to produce; if it is too low, the reaction will be slow. After the reaction is completed, after the separation and purification steps to remove its impurities, pure 2 - (chloromethyl) -1 - methyl - 4 - (trifluoromethyl) benzene can be obtained. In this way, it is a good way to prepare this substance.
    Chemical Reactions & Modifications
    Nowadays, there is a chemical substance named 2 - (chloromethyl) -1 -methyl-4- (trifluoromethyl) benzene. Our generation is a chemical researcher to explore its reaction and modification.
    Looking at this compound, its structure is unique, chloromethyl, methyl and trifluoromethyl coexist in a benzene ring. This structure makes it have special chemical properties. Its chloromethyl is active and prone to nucleophilic substitution, which can be the path for introducing new groups.
    However, if you want to optimize its properties, you need to change it. Mild conditions can be selected to make the reaction precise. For example, with suitable reagents, the reaction rate and direction can be regulated, and the purity and yield of the product can be increased. Or modify its structure, change the substituent, change its physical and chemical properties, so that it is more widely used in materials, medicine and other fields.
    We should study its reaction mechanism in a rigorous manner and find a good method for modification. We hope this compound can show greater function.
    Synonyms & Product Names
    2 - (chloromethyl) -1 - methyl - 4 - (trifluoromethyl) benzene, the synonym and trade name of this substance, is quite valuable for investigation. I look at the chemical research of ancient times, and I also use the same name to distinguish the substance. In today's chemical field, this compound has a wide range of uses, but its name may have another name.
    Looking back at the past, the names of chemical substances often change with the changes of times and regional differences. Just like a certain medicine, it had its name in ancient times, and now it has a new name. The connection between them seems to be in the same vein. 2 - (chloromethyl) -1 - methyl - 4 - (trifluoromethyl) benzene, or in different literature and industries, has different expressions.
    Knowing its synonyms and trade names is beneficial to scientific research and production. Scientists can find things by name without confusion; producers can also pinpoint and clarify raw materials. Therefore, exploring the synonyms and trade names of this thing is the priority of chemical research, which can pave the way for the development of the industry.
    Safety & Operational Standards
    Safety and Operation Specifications for Bis- (Chloromethyl) -1 -Methyl-4- (Trifluoromethyl) Benzene
    Fubi- (Chloromethyl) -1 -Methyl-4- (Trifluoromethyl) Benzene is an important substance in chemical research. Its experimental operation and research process are of the utmost importance to safety.
    This substance has certain chemical activity and is prone to reaction in contact with water or humid air. Therefore, when storing, it must be in a dry, cool and well-ventilated place, away from water sources and moisture, to prevent unexpected chemical reactions. When taking it, the experimenter needs to wear complete protective equipment, such as protective clothing, gloves and goggles, to protect himself from possible damage.
    Operating specifications are also crucial. Before the experiment, make sure that the equipment used is clean, dry and functional. During the reaction process, temperature, pressure and other conditions must be precisely controlled. Because of its reaction or heat generation and gas production, if it is not properly controlled, it may be dangerous. The stirring speed also needs to be appropriate to promote a uniform reaction and ensure the stability of the experimental effect.
    Furthermore, the experimental site must be equipped with complete ventilation devices to expel harmful gases generated by the reaction in time and keep the indoor air fresh. Waste disposal should be sorted and collected in accordance with relevant regulations, and properly disposed of, so as not to pollute the environment.
    To sum up, the research and operation of bis- (chloromethyl) -1 -methyl-4- (trifluoromethyl) benzene, safety and regulation, such as two wheels of the car and two wings of the bird, are indispensable. Only by following these two can the experiment be smooth, the personnel are healthy, and the environment is clean and beautiful.
    Application Area
    Today there is a product called 2 - (chloromethyl) -1 -methyl-4- (trifluoromethyl) benzene. This chemical product has its uses in various fields.
    In the field of pharmaceutical research and development, it can be a key raw material. Through delicate chemical reactions, it can help synthesize special drugs, heal diseases, and save lives.
    In the field of materials science, its performance is unique. It can participate in material synthesis and endow materials with special properties, such as enhancing their stability and weather resistance, for the manufacture of high-end materials, used in aerospace, electronic equipment, etc.
    In the agricultural chemical industry, it can be used as an intermediate to help create high-efficiency pesticides, protect crops from pests, ensure a bumper harvest, and benefit the stability of people's lives. It is widely used and indispensable in many industries. It is also an important substance in chemical research and industrial production.
    Research & Development
    Today there is a substance called 2- (Chloromethyl) -1-Methyl-4- (Trifluoromethyl) Benzene. We study it chemically to study its properties and explore its changes.
    To study the formation of this substance, it is necessary to observe various reaction conditions. Or at a certain temperature, catalyze with a certain agent to make the raw materials polymerize. To get a good effect, you must carefully control the temperature and dosage, and it is not bad at all.
    As for its development, it can be used in a wide range of fields. Or in medicine, to help make good medicines and treat human diseases; or in materials, additive properties, to expand its use.
    However, when studying this substance, you also need to be cautious. Its nature or intensity, improper operation, fear disaster. Therefore, we study day and night, with the aim of using scientific methods to control its advantages and disadvantages, promote its development, and use it for the benefit of the world.
    Toxicity Research
    The toxicity of 2 - (chloromethyl) -1 - methyl - 4 - (trifluoromethyl) benzene is deeply felt in this study. This substance may contain hidden concerns, which are related to the health of living beings and the tranquility of the environment.
    Examine its properties in detail, in the experimental environment, apply it to various objects, and observe its changes. See its encounter with living creatures, or disturb the order of physiology, damage the energy of cells, and even endanger life. And this substance may have lasting properties, and it may persist in the environment. It accumulates in the chain of water, soil, and organisms.
    We should explore its toxicology with a rigorous heart, study the mechanism of action, and understand the wide range of harm. The theory of accuracy is expected to be the foundation of protection and governance, to ensure the health of all beings, to protect the peace of heaven and earth, and to avoid this potential danger, and to live up to the responsibility of the researcher.
    Future Prospects
    I have dedicated myself to the research of this 2- (Chloromethyl) -1-Methyl-4- (Trifluoromethyl) Benzene compound. This material is unique and has infinite potential in various fields. Looking at current research, although some progress has been made, there is still a wide way to expand in the future.
    Future prospects, one can be explored in the application of pharmaceutical research and development. Or with its unique structure, it can create novel and special drugs to save people from pain. Second, it is also promising in materials science. After ingenious modification, it can be made into high-performance special materials, which can contribute to scientific and technological progress. Third, in fine chemicals, it can be used as a key intermediate to derive a variety of high-value-added products.
    I firmly believe that with time and unremitting research, this 2- (Chloromethyl) -1-Methyl-4- (Trifluoromethyl) Benzene will shine brightly, pave the way for future development, and become the bright fruit of my generation's scientific research.
    Where to Buy 2-(Chloromethyl)-1-Methyl-4-(Trifluoromethyl)Benzene in China?
    As a trusted 2-(Chloromethyl)-1-Methyl-4-(Trifluoromethyl)Benzene manufacturer, we deliver: Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements. Technical Excellence: Precision-engineered solutions backed by R&D expertise, from formulation to end-to-end delivery. Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.
    Frequently Asked Questions

    As a leading 2-(Chloromethyl)-1-Methyl-4-(Trifluoromethyl)Benzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

    What are the main uses of 2- (chloromethyl) -1-methyl-4- (trifluoromethyl) benzene?
    2-% (cyanomethyl) -1-methyl-4- (trifluoromethyl) pyridine, which has a wide range of uses. In the field of medicine, it is used as a key intermediate to help synthesize many specific drugs. Due to its unique chemical structure and properties, it can precisely combine with specific targets in organisms to achieve disease treatment. For example, in the development of some antidepressant drugs, it can optimize the activity of drug molecules, enhance the regulation of neurotransmitters, and improve the therapeutic effect of drugs.
    In the field of pesticides, it is also an important raw material. With its unique mechanism of action against pests, high-efficiency and low-toxicity pesticides can be prepared. For example, for some piercing mouthpart pests, pesticides containing this ingredient can interfere with the nervous system or physiological metabolic process of pests, achieve good insecticidal effect, and are relatively friendly to the environment, with low residue, which is conducive to ecological and environmental protection.
    In the field of materials science, 2-% (cyanomethyl) -1-methyl-4- (trifluoromethyl) pyridine can participate in the synthesis of special functional materials. By polymerizing with other monomers, the material is endowed with excellent properties such as chemical resistance and thermal stability. For example, in the preparation of some high-performance engineering plastics, the addition of this substance can improve the weathering resistance and mechanical properties of the plastic, so that it can maintain stable physical and chemical properties in extreme environments, and is widely used in high-end fields such as aerospace and automobile manufacturing.
    What are the physical properties of 2- (chloromethyl) -1-methyl-4- (trifluoromethyl) benzene?
    2-% (cyanomethyl) -1-methyl-4- (trifluoromethyl) benzene, this substance has many physical properties. Its appearance is often colorless to slightly yellow transparent liquid, stable at room temperature and pressure.
    Looking at its smell, it has a special organic aromatic smell, but the intensity of this smell is related to the specific purity and environmental conditions. When it comes to melting point, the substance has a relatively low melting point and condenses from liquid to solid at a specific low temperature. In terms of boiling point, because its molecular structure contains special groups, the boiling point is within a certain range and can change from liquid to gas at the corresponding temperature.
    In terms of solubility, it exhibits good solubility in organic solvents such as ethanol, ether, dichloromethane, etc., and can be miscible with these organic solvents in a specific ratio. However, its solubility in water is extremely poor, because it is an organic compound with a large polar difference from water. It follows the principle of similar miscibility and is difficult to dissolve in water.
    Density is also an important physical property. It is similar to the density of common organic solvents. When placed in a specific liquid, it will appear stratified according to the density. In addition, the substance also has a certain degree of volatility, which will evaporate slowly at room temperature and slightly faster in a well-ventilated environment. And its vapor density is higher than that of air, and the vapor is easy to accumulate at a lower place after volatilization.
    Is 2- (chloromethyl) -1-methyl-4- (trifluoromethyl) benzene chemically stable?
    To investigate the stability of its chemical properties, the chemical properties are related to the structure of molecules, the bonding of atoms, and the conditions of temperature, pressure and medium in the outside world.
    In terms of its structure, cyanomethyl group has strong electron-withdrawing, which can cause the electron cloud density to change at the ortho-pyridine ring and affect the reactivity of the pyridine ring. Methyl group, as the power supply group, can increase the ortho-electron cloud density, but its electron-withdrawing effect is weaker than that of cyanyl group. Trifluoromethyl, on the other hand, has extremely strong electron-withdrawing properties, and its position at the 4th position of the pyridine ring makes the electron cloud density distribution of the pyridine ring more uneven. Such a structure makes the charge distribution of the pyridine ring different from usual, causing its activity to change.
    When it comes to stability, the tension and charge distribution of the structure are key. (2- (cyanomethyl) -1-methyl-4- (trifluoromethyl) pyridine) structure, due to the electronic effect of different substituents, makes the charge distribution in the molecule uneven, or causes a certain tension in the molecule. In chemical reactions, this tension may make the molecule tend to react to reduce tension and reach a stable state.
    Looking at the external conditions, the temperature increases, the thermal motion of molecules intensifies, the energy increases, or the bonds within the molecules are easily broken, and the stability decreases; the change of pressure or the distance and interaction between molecules affect the stability of the substance, which is less than the temperature. In different media, polar media or electrostatic interaction with molecules affects their charge distribution, while non-polar media mainly interact with molecules through van der Waals forces. If the medium interacts strongly with molecules, or changes the strength of chemical bonds and the stability of molecules.
    In summary, the chemical properties of (2- (cyanomethyl) -1 -methyl-4- (trifluoromethyl) pyridine) have certain activity due to the electronic effect of the substituents in the structure, and the stability is not very high. Under suitable conditions, a chemical reaction may occur to achieve a more stable state.
    What are the preparation methods of 2- (chloromethyl) -1-methyl-4- (trifluoromethyl) benzene?
    To prepare 2 - (methoxy) -1 -methyl-4 - (trifluoromethyl) benzene, the method is as follows:
    First, you can start from a suitable aryl halide. Select an aryl halogen containing the corresponding substituent, such as a p-halotoluene derivative, under appropriate conditions, and carry out a nucleophilic substitution reaction with a methoxylating agent, such as sodium methoxide, to introduce the methoxy group. Then, through a specific fluorinating agent, such as a trifluoromethylating agent, such as sodium trifluoromethanesulfonate, etc., under suitable catalyst and reaction conditions, trifluoromethyl is introduced to obtain the target product. This process requires attention to the precise control of reaction conditions, including temperature, solvent, catalyst dosage, etc., to ensure the selectivity and yield of the reaction.
    Second, benzene derivatives are used as raw materials. First, the benzene ring is methylated, and suitable methylation reagents, such as iodomethane and corresponding catalysts, are selected to achieve the introduction of methyl groups on the benzene ring. Next, the benzene ring is connected to a specific position by a suitable methoxylation method. Finally, with the help of trifluoromethylation reaction, the use of suitable trifluoromethylation reagents and reaction conditions, the successful introduction of trifluoromethyl groups to achieve the preparation of the product. This path also focuses on the sequence of reaction steps and the optimization of reaction conditions in each step to prevent unnecessary side reactions.
    Third, starting from benzene derivatives containing partially substituted groups. If there are benzene derivatives containing methoxy and methyl groups, halogen atoms can be introduced directly to the remaining positions through a suitable halogenation reaction. After that, trifluoromethylation reagents are used to achieve the substitution of trifluoromethyl under the catalysis of suitable metal catalysts, and then 2- (methoxy) -1 -methyl-4- (trifluoromethyl) benzene is obtained. This approach requires attention to the selectivity of the halogenation reaction, as well as the efficiency and selectivity of the subsequent trifluoromethylation reaction.
    All kinds of preparation methods have their own advantages and disadvantages. In actual operation, it is necessary to comprehensively consider many factors such as the availability of raw materials, cost, and difficulty of reaction conditions to choose the optimal preparation method.
    What should be paid attention to when storing and transporting 2- (chloromethyl) -1-methyl-4- (trifluoromethyl) benzene?
    This substance (2 - (methoxy) -1 - methyl - 4 - (trifluoromethyl) benzene) requires a lot of attention during storage and transportation.
    One of them is related to storage. This substance is quite sensitive to environmental conditions and should be placed in a cool, dry and well-ventilated place. If it is placed in a high temperature and humid environment, it may cause chemical reactions and cause its properties to change. Just like the ancient elixir, it needs to be placed in a specific furnace to be suitable for heat and humidity maintenance to ensure its efficacy. The same is true for this substance. High temperature easily activates molecules, or causes reactions such as decomposition and polymerization; humid gas easily makes it damp, affecting purity and stability.
    Second, as far as transportation is concerned, the packaging must be strong and well sealed. This is to ensure that during transportation, it is not disturbed by vibration, collision and external environment. Just like the ancient escort treasures, it is necessary to use a sturdy wooden box, filled with soft objects to prevent shock, and sealed to prevent accidents during transportation. When transporting the substance, the container used must be able to withstand its chemical corrosion and prevent leakage. Because of its certain chemical activity, if the leakage comes into contact with air, moisture or other substances, or it may cause dangerous reactions.
    Furthermore, whether it is stored or transported, it is necessary to strictly abide by relevant laws and standards. This is like the ancients acting in accordance with the rules and regulations, which cannot be exceeded. Relevant practitioners should be familiar with and follow the regulations to ensure operational compliance. From the choice of storage location, facilities, to the qualifications of transportation vehicles and personnel, all requirements should be met.
    It is also necessary to pay attention to its compatibility with surrounding substances. When storing, do not coexist with substances that are easy to react; during transportation, you should also avoid being in the same car with objects that are mutually exclusive. This is like the five elements of life, each in its place to ensure safety. In this way, it can be stored and transported (2 - (methoxy) -1 - methyl - 4 - (trifluoromethyl) benzene) to ensure its safety and stability.