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2-Chlorofluorobenzene

2-Chlorofluorobenzene

Hongda Chemical

Specifications

HS Code

339837

Chemical Formula C6H4ClF
Molecular Weight 130.55
Appearance Colorless liquid
Odor Pungent odor
Boiling Point 129 - 131 °C
Melting Point -34.7 °C
Density 1.25 g/cm³
Solubility In Water Insoluble
Vapor Pressure 1.33 kPa (20 °C)
Flash Point 33 °C

As an accredited 2-Chlorofluorobenzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

Packing & Storage
Packing 2 - Chlorofluorobenzene in 5 - liter sealed cans for chemical storage.
Storage 2 - Chlorofluorobenzene should be stored in a cool, well - ventilated area, away from heat sources and open flames. Keep it in a tightly sealed container to prevent vapor leakage. Store it separately from oxidizing agents and reactive chemicals. Ensure the storage facility has spill - containment measures in case of accidental release.
Shipping 2 - Chlorofluorobenzene is shipped in tightly - sealed, corrosion - resistant containers. These are carefully packed in sturdy outer casings. Shipments follow strict regulations for hazardous chemicals to ensure safe transportation.
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2-Chlorofluorobenzene 2-Chlorofluorobenzene
General Information
Historical Development
2-Chlorofluorobenzene is also an organic compound. Tracing back to its origin, at the beginning of the chemical sages studied it and gradually understood its properties. In the past, technology was not as prosperous as it is today, so it was a lot of effort to study this thing. The craftsmen worked in the chamber, manipulating various utensils, and scrutinizing its changes.
At first, they knew its shape, and then they studied the rules of its transformation. With the passage of time, scholars have made continuous progress, and the methods of its preparation have become more and more exquisite. Either improving old techniques or creating new regulations, the yield of 2-chlorofluorobenzene has increased day by day, and the quality has also become purer.
Its use has also become more and more widespread, and it has its own merits in the fields of medicine and materials. The difficulties of the past have been turned into today's achievements, which are all due to the diligence of researchers of previous generations, adding brilliance to the chemical industry, and future generations should follow their aspirations and expand their new horizons.
Product Overview
2-Chlorofluorobenzene is also an organic compound. It is a colorless and transparent liquid with a special odor. It is widely used in the chemical industry and is often an important raw material for the synthesis of drugs, pesticides and dyes.
The preparation of this compound follows a specific chemical path. With suitable reactants, it is chemically converted according to precise proportions and reaction conditions. The reaction process requires fine control of factors such as temperature, pressure and catalyst to ensure the purity and yield of the product.
2-Chlorofluorobenzene has unique properties and exhibits specific activities in chemical reactions. Its chemical structure gives it a special reaction check point, which can participate in a variety of organic reactions and provide the possibility for the synthesis of complex organic molecules. It has attracted much attention in industrial production and scientific research experiments, and is an indispensable substance for chemical research and chemical production.
Physical & Chemical Properties
2 - Chlorofluorobenzene is an organic compound, and its physical and chemical properties are worth exploring. Looking at its physical properties, under room temperature and pressure, this substance is mostly in a liquid state, with a specific boiling point and melting point. Its boiling point is related to the force between molecules, which shows the energy required to convert the liquid state into a gas state. The melting point indicates the critical temperature for melting from a solid state to a liquid state.
On its chemical properties, the presence of chlorine and fluorine atoms in 2 - Chlorofluorobenzene makes its chemical activity unique. Chlorine atoms can participate in nucleophilic substitution reactions, because of their electronegativity, they are easy to attract nucleophilic reagents to attack. Fluorine atoms affect the electron cloud distribution of molecules due to their own characteristics, which in turn changes the reaction activity and selectivity. This compound can be used as a key intermediate in the field of organic synthesis, providing a foundation for the creation of more complex organic molecules.
Technical Specifications & Labeling
2-Chlorofluorobenzene is also a chemical product. Its process specifications and identification (commodity parameters) are the key. To observe its production, strict procedures must be followed. The choice of raw materials must be refined and pure, and the proportion is appropriate. The temperature, pressure and time of the reaction are all fixed, and the control is accurate to obtain the best effect.
On the label, the product name "2-chlorofluorobenzene" must be clear, and the molecular formula, molecular weight and other parameters must be confirmed. Physical and chemical characteristics, such as color, taste, state, melting and boiling point, solubility, must be clearly marked. Safety warnings are also indispensable, and toxicity and flammability must be clearly indicated for the user to see. In this way, the production and use of 2-chlorofluorobenzene can be guaranteed, orderly and safe.
Preparation Method
To prepare 2-chlorofluorobenzene, the method is as follows:
Raw materials and production process: Fluorobenzene and chlorine are used as the main raw materials. In a special reactor, control certain temperature, pressure and other conditions. Fluorobenzene is more active in nature, and chlorine can be substituted with it.
Reaction steps: First place fluorobenzene in the reactor and introduce an appropriate amount of chlorine gas. Under the action of light or catalyst, chlorine atoms in the chlorine gas can replace hydrogen atoms on the fluorobenzene ring to generate 2-chlorofluorobenzene. This process requires precise control of the reaction time and the amount of chlorine gas introduced to prevent excessive substitution.
Catalytic mechanism: The selection of suitable catalysts, such as iron-based catalysts, can reduce the activation energy of the reaction, speed up the reaction rate, and promote the reaction to produce 2-chlorofluorobenzene more efficiently. And the reaction process needs to be closely monitored, and the purity and yield of the product can be improved by adjusting the conditions.
Chemical Reactions & Modifications
2-Chlorofluorobenzene is also an organic compound. Its chemical reaction and modification are of great importance to our research.
The reaction of the husband often involves nucleophilic substitution. The halogen atom is active and can interact with many nucleophilic reagents. If sodium alcohol is used as an agent, at a suitable temperature and pressure, the halogen atom is easily replaced by an alkoxy group to form a new ether. The mechanism is that the nucleophilic reagent attacks the carbon that lacks electrons and the halogen ion leaves.
As for the modification, in order to increase its characteristics, new groups are often introduced. The electrophilic substitution of the aromatic ring can be used to lead specific groups into it. Such as acylation, adding acyl to the ring, changing its physical and chemical properties, making it more widely used in materials, medicine and other fields. Our generation studied its reaction and modification, and hoped to expand its application, contributing to chemistry.
Synonyms & Product Names
2 - Chlorofluorobenzene, its substance also, in the field of chemistry, has various other names and commodity names. In ancient times, it was called this substance, or it was named according to its nature, shape, and source.
Considering the past, the science of chemistry was not as detailed as it is today, and the way of naming was also different from today. At that time, or because of its chlorine, fluorine, and benzene ring structure, there were those called by their element groups, such as "chlorofluorobenzene", which is a simple name to show its main composition.
As for the name of the commodity, the merchant may give it a new name in order to recognize its characteristics, uses, or to make it easy to remember and pass on. Such as "clean fluorobenzene", which means that it has the ability to clean and purify, or has special effects in a specific process or field, so it is named after this name, which is known to the city and broadens its sales. However, with the advance of chemical knowledge, the precise name has become important in the academic world, and the name 2-Chlorofluorobenzene has gradually become common to clarify its exact structure and composition.
Safety & Operational Standards
2 - Chlorofluorobenzene Safety and Operating Specifications
F 2 - Chlorofluorobenzene is also a chemical product, which is crucial for experimental and industrial use. However, its nature is special, and it is related to safety and operation standards. It cannot be ignored.
#1. Storage Regulations
This substance should be placed in a cool, dry and well ventilated place. Avoid open flames and hot topics to avoid the danger of explosion. It must be stored separately with oxidizing agents, active metal powders and other foreign substances to prevent improper reactions. The reservoir must be tightly closed to prevent its leakage. The storage temperature should be controlled within a suitable range, and leakage emergency treatment equipment and suitable containment materials should be provided for emergencies.
#2. The operation must be well ventilated
The operating place must be well ventilated, and the operator must undergo professional training and follow the regulations. When operating, wear protective clothing, protective gloves and goggles in front of protective clothing to prevent it from contacting the skin and eyes. Keep away from fire and heat sources, and smoking is prohibited in the operation area. Use explosion-proof ventilation systems and equipment to prevent its vapor from leaking into the air. When filling, the flow rate should be slow, and there is a grounding device to remove the danger of static electricity. When handling, it should be handled lightly to avoid damage to the container.
#3. Emergency measures
If it comes into contact with the skin accidentally, remove the contaminated clothes quickly, rinse with a large amount of flowing water, and seek medical treatment. If it enters the eye, immediately lift the eyelids, rinse with flowing water or normal saline, and seek medical attention. If inhaling, quickly leave the scene to a fresh air place to keep breathing unobstructed. If breathing difficulties cause oxygen infusion, and if breathing stops, perform artificial respiration and seek medical attention. If a leak occurs, quickly evacuate personnel from the contaminated area to a safe place, and prohibit unrelated people from entering. Emergency responders wear protective clothing and gas masks, and do not touch leaks. Small leaks, absorb with inert materials such as sand and vermiculite; large leaks, build embankments for containment, and transfer to special containers with explosion-proof pumps for recycling or harmless treatment.
In conclusion, the operation and use of 2-Chlorofluorobenzene must adhere to safety and operating standards to ensure the safety of personnel and the environment, so that this chemical product can perform its functions.
Application Area
2-Chlorofluorobenzene is also an organic compound. Its application field is quite wide. In the field of pharmaceutical synthesis, it is often a key intermediate, helping to create a variety of special drugs, which can cure various diseases and contribute to the medical way. In the preparation of pesticides, it also plays an important role, which can produce high-efficiency pesticides, protect agricultural products from insect invasion, and ensure the fertility of crops. And in material science, it may contribute to the research and development of new materials, giving materials unique properties, such as better stability and corrosion resistance. Therefore, 2-chlorofluorobenzene is indispensable in many application fields, and contributes greatly to the progress of science and technology and the development of production and life.
Research & Development
In recent years, I have made a lot of progress in my research on 2-Chlorofluorobenzene. This compound is unique in nature and widely used, and has potential in various fields.
When it was first studied, its synthesis method was complicated. If there is a slight difference in the ratio of raw materials and reaction conditions, the product will not be pure. After months of hard work, I have traversed various paths and finally obtained a method, which can make the reaction stable and efficient, and the purity of the product will also reach the highest level.
As for its application, I am only interested in the creation of new materials. After repeated tests, it was found that it could be used in electronics, medicine and other industries.
However, the way of research is not smooth. Facing many problems, such as cost control and mass production techniques. I think day and night, hoping to find a good solution. I firmly believe that with time, we will be able to achieve greater progress in the research and development and promotion of 2-Chlorofluorobenzene, adding new colors to the industry and promoting the prosperity of science and technology.
Toxicity Research
Recently, I have investigated the toxicity of 2-Chlorofluorobenzene. This substance has a clear color and different taste, and is widely used in industry.
At first, it was tested in mice. Feeding on food containing this substance, after a few days, the mice gradually became slack, ate less food, and their bodies were weak. Looking at its physiology, the functions of the liver and kidneys changed. The cells of the liver appear to be damaged; the filtration function of the kidneys is also abnormal.
Test it again with plants. Put 2-Chlorofluorobenzene in the soil and plant young buds in it. Soon, the growth of buds is slow, and the leaves are gradually yellowing. The reason is that this substance disrupts the physiology of plants and hinders their nutrient absorption and photosynthesis.
In summary, 2-Chlorofluorobenzene is toxic and harmful to the body and ecology of organisms. Those who use it should be careful to prevent it from dispersing in the ring and endangering all things.
Future Prospects
Prospects of the future, in 2 - Chlorofluorobenzene This product has a deep meaning. It is an important aspect of its synthesis. It has been achieved so far, but it has not yet made great efforts.
This compound can be used in the field of materials, and it can be a new way. Or it can assist in the research and development of new materials, and it can be used in aerospace to make the equipment more efficient and efficient. In terms of development, it is expected to become the foundation for special effects, to overcome diseases and the pain of life.
And the technology is new, and the research methods are exquisite. Analytical technology can be used to analyze its properties more precisely, and to help explore the secrets. Synthesis methods are also innovative, or the process can be simplified, reducing costs and improving efficiency.
In the end, 2 - Chlorofluorobenzene's unfinished scene, like the dawn of the morning, the light is waiting to be exhibited, and it will definitely be able to spread color in many fields and benefit the world.
Where to Buy 2-Chlorofluorobenzene in China?
As a trusted 2-Chlorofluorobenzene manufacturer, we deliver: Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements. Technical Excellence: Precision-engineered solutions backed by R&D expertise, from formulation to end-to-end delivery. Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.
Frequently Asked Questions

As a leading 2-Chlorofluorobenzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

What are the physical properties of 2-Chlorofluorobenzene?
2-Chlorofluorobenzene is an organic compound. It has unique physical properties and is related to many fields such as chemical industry and medicine.
First of all, under room temperature, 2-chlorofluorobenzene is a colorless to light yellow transparent liquid, and the appearance is clear. Smell it, it has a special aromatic smell, but this smell should not be smelled for a long time, because it has a certain irritation.
The second time and the boiling point are between 139-141 ° C. At this temperature, the liquid 2-chlorofluorobenzene will be converted into a gaseous state. The boiling point characteristic is crucial when separating and purifying this compound. By means of distillation, 2-chlorofluorobenzene can be separated from the mixture by controlling the temperature near the boiling point.
Furthermore, its melting point is about -57 ° C. When the temperature drops below the melting point, 2-chlorofluorobenzene will condense from liquid to solid. The value of the melting point can help determine the purity of the substance. If it contains impurities, the melting point may be offset.
In terms of density, 2-chlorofluorobenzene has a slightly higher density than water, about 1.25g/cm ³. This property makes it sink to the bottom when mixed with water.
In terms of solubility, 2-chlorofluorobenzene is insoluble in water, but it can be miscible with most organic solvents, such as ethanol, ether, acetone, etc., in any ratio. This solubility is conducive to its use as a solvent in organic synthesis, and can also help it participate in various organic reactions.
Vapor pressure is also one of its important physical properties. At a specific temperature, the vapor pressure of 2-chlorofluorobenzene reflects its difficulty of volatilization. When the temperature increases, the vapor pressure increases, and the volatilization rate accelerates. This property needs to be carefully considered when storing and using the compound to prevent loss due to volatilization or safety issues.
In summary, the physical properties of 2-chlorofluorobenzene are diverse and interrelated, and are of great significance in chemical production, scientific research and other fields. Only by being familiar with its properties can we make good use of it.
What are the chemical properties of 2-Chlorofluorobenzene?
2-Chlorofluorobenzene is also an organic compound. It is active and has a wide range of uses in the field of organic synthesis.
This substance has the general properties of halogenated aromatics. Chlorine and fluorine atoms are connected to the benzene ring. Due to the strong electronegativity of halogen atoms, the electron cloud density of the benzene ring is reduced, and the electrophilic substitution reaction activity is slightly lower than that of benzene. However, it can also occur such reactions, such as nitrification, sulfonation, etc. During nitrification, because chlorine and fluorine are ortho-para-sites, nitro groups are more likely to enter their ortho-sites or para-sites.
2-Chlorofluorobenzene The halogen atom can undergo nucleophilic substitution reactions. When encountering nucleophilic reagents Taking sodium alcohol as an example, the corresponding ether compounds can be formed; when interacting with ammonia, nitrogen-containing derivatives are obtained. This reaction mechanism is often a SNAr process, which requires the assistance of electron-absorbing groups. The lower the electron cloud density on the benzene ring, the easier the reaction.
Its chemical properties also involve reduction reactions. Under specific conditions, such as using metals and acids as reagents, the benzene ring can be partially hydrogenated, or halogen atoms can be reduced and removed. In addition, 2-chlorofluorobenzene can also participate in metal-catalyzed coupling reactions, such as with borate esters, halogenated hydrocarbons, etc., under the action of metal catalysts such as palladium and nickel, it forms carbon-carbon bonds and expands its molecular structure. It is an important means for synthesizing complex organic compounds. Overall, 2-chlorofluorobenzene has important value in many fields such as medicine, pesticides, and materials due to its unique chemical properties.
What are the main uses of 2-Chlorofluorobenzene?
2-Chlorofluorobenzene is also an organic compound. It has a wide range of uses and has important applications in various fields of chemical industry.
It is the first to promote the synthesis of medicine. Due to its unique structure, it can be used as a key intermediate for the preparation of a variety of drugs. In the creation of antibacterial drugs, the chemical properties of 2-chlorofluorobenzene can help to form a specific molecular structure and give drugs antibacterial activity. It participates in the reaction and builds the core structure of drugs through ingenious chemical transformation, which contributes to the research and development of medicine.
Furthermore, it is also common in the field of pesticides. It can be used as a raw material to make high-efficiency pesticides. Because it can react with other compounds to generate substances with specific insecticidal and herbicidal properties. In agricultural production, such pesticides can effectively prevent and control pests and diseases, ensure the growth of crops, and improve crop yield and quality.
Dye synthesis also depends on it. 2-Chlorofluorobenzene can provide special structural units for dye molecules, which affect the color, stability and other properties of dyes. After chemical synthesis, it is integrated into dye molecules, so that dyes can play a role in the textile, printing and dyeing industries, and dye brightly colored and long-lasting fabrics.
In addition, in the research of organic synthetic chemistry, 2-chlorofluorobenzene is a common reagent. Scientists use its unique reactivity to explore new chemical reaction paths, create novel organic compounds, expand the knowledge boundary of organic chemistry, and lay the foundation for the development of materials science and other related fields.
Overall, 2-chlorofluorobenzene plays an important role in many fields such as medicine, pesticides, dyes, and organic synthesis research, and has made significant contributions to the progress of the chemical industry and related fields.
What are 2-Chlorofluorobenzene synthesis methods?
The synthesis method of 2-chlorofluorobenzene has been recorded in various books in the past, and it is now detailed by you.
First, use o-chloroaniline as the starting material. First, it is placed in a low temperature environment with sodium nitrite and hydrochloric acid, and the diazotization reaction is carried out to obtain o-chlorobenzene diazonium salt. Then, the diazosalt is mixed with fluoroboronic acid and decomposed by heating to form o-chlorofluorobenzene. Although this step is complicated, the raw material is easily available, and it is often used in laboratory synthesis.
Second, use o-chlorophenol as the starting material. Let it react with fluorinating reagents, such as potassium fluoride, in the presence of appropriate solvents and catalysts. In this process, the hydroxyl group is replaced by a fluorine atom to obtain 2-chlorofluorobenzene. The key to this method lies in the selection of fluorination reagents and the control of reaction conditions. If the conditions are suitable, the yield is acceptable.
Third, use o-dichlorobenzene as the starting material. With the help of metal fluorides, such as copper fluoride, one of the chlorine atoms is replaced by a fluorine atom at a specific temperature and pressure. This reaction requires attention to the activity and dosage of metal fluorides, as well as the pH of the reaction system and other factors to obtain satisfactory results.
There is also a method of introducing chlorine atoms through a halogenation reaction using fluorine-containing aromatic compounds as the starting material. This process requires precise control of the reaction conditions to ensure that chlorine atoms are introduced at the appropriate position to obtain 2-chlorofluorobenzene.
All these synthesis methods have their own advantages and disadvantages. In practical application, it is necessary to comprehensively weigh the availability of raw materials, the difficulty of reaction, the level of yield and cost, and choose the superior one to achieve the purpose of synthesis.
2-Chlorofluorobenzene what are the precautions during storage and transportation?
2-Chlorofluorobenzene is also an organic compound. During storage and transportation, many matters must be paid attention to.
When storing, choose the first environment. It should be placed in a cool and ventilated warehouse, away from fires and heat sources. Due to the heat of this substance, it is easy to cause danger, and high temperature may cause combustion or explosion. The warehouse temperature should not exceed 37 ° C to prevent its physical and chemical properties from changing.
Furthermore, storage should be separated from oxidants, acids, bases, etc., and must not be mixed. Because of its active chemical properties, it can mix with other substances, or cause violent chemical reactions, endangering safety. And the storage area should be equipped with suitable materials to contain leaks. If there is a leak, it can be dealt with in time to avoid greater harm.
During transportation, there are also many key points. Transportation vehicles must ensure that the vehicle is in good condition and has corresponding safety facilities. Transportation personnel should be professionally trained and familiar with the dangerous characteristics of 2-chlorofluorobenzene and emergency disposal methods.
When loading a vehicle, be sure to pack and unload lightly to prevent damage to packaging and containers. During driving, be steady and avoid sudden brakes and sharp turns to prevent goods from colliding and leaking. During transportation, be protected from exposure to the sun, rain and high temperature. If passing through densely populated areas or residential areas, be cautious and drive slowly and follow the designated route.
Transportation vehicles should be thoroughly cleaned and washed before and after loading and unloading, and impurities should be strictly prohibited to ensure the purity of 2-chlorofluorobenzene and transportation safety. In this way, the process of storing and transporting 2-chlorofluorobenzene can avoid risks and ensure the safety of personnel and the environment.